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Wyniki wyszukiwania dla: candida krusei
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On the influence of shell element properties on the response of car model in crash test
PublikacjaIt goes without saying that numerical simulations play important role in the modern engineering practice. Contemporary CAD environments combined with FEM solvers, along with computer power of modern processors, give the engineer fast and efficient tool. Ultimately, however it is the user alone who is responsible for the correctness of the results. As long as the FEM calculations remain in the sphere of academic exercise, the inevitable...
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TB11 test for short w-beam road barrier
PublikacjaFEM (Finite Element Method) is well-suited and widely used tool for simulating a range of phenomena: from these with simple and static behaviour, up to those complicated, highly nonlinear and involving many contacts. In present paper we use one of the advantages of FEM: parametric study could be easily performed and is more economical than series of in-situ tests. If recommended practices is carefully followed, results obtained...
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Influence of a Lighting Column in the Working Width of a W-Beam Barrier on TB51 Crash Test
PublikacjaRoad equipment, such as, e.g., road safety barriers and lighting columns, are subject to certification according to the EN1317 standard to be allowed for use on European roads. In engineering practice, due to the terrain conditions, there are cases where other road equipment is installed within the working width of road safety barriers. Such situations are not considered during the certification process. Hence, the aim of this...
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Numerical crash analysis of the cable barrier
PublikacjaSafety barriers are used to increase road safety. Their basic task is to prevent the errant vehicle from getting off the road in places which are potentially dangerous for vehicle passengers. Barriers, which are used on European roads, must fulfill the requirements of EN 1317 standards by passing appropriate crash tests. Because of their high cost, numerical simulations are increasingly used to evaluate the properties of safety...
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Tubular adenocarcinoma - Male, 73 - Tissue image [7100730013396711]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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Dopiero doświadczenie pokazuje, że nie jestem aż tak dobry – o malejącym poczuciu samoskuteczności wśród początkujących przedsiębiorców
PublikacjaW artykule prezentowane są wyniki badań ankietowych przeprowadzonych w grupie 76 przedsiębiorców, założycieli mikrofirm. Osoby badane były ankietowane po raz pierwszy na początku prowadzenia działalności – w czasie nie późniejszym niż 6 miesięcy od momentu założenia firmy oraz ponownie po upływie roku od pierwszej ankiety. Analiza statystyczna uzyskanych wyników wykazała, że w badanej grupie przedsiębiorców w sposób istotny obniżył...
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Docking simulations, Molecular properties and ADMET studies of novel Chromane6,7diol analogues as potential inhibitors of Mushroom tyrosinase
PublikacjaResearch on inhibition of tyrosinase enzyme has attained significant value, because tyrosinase inhibitors have potential applications in medicine, cosmetics (as whitening agents) and in agriculture (as bioinsecticides). Determination and elucidation of new tyrosinase inhibitors are not only beneficial for medical purposes, but their promising applications in improving food quality and nutritional...
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Mohamed Abouzid
OsobyPassionate about clinical sciences and epigenetics
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Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors
PublikacjaNumerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...
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Ergonomia i ochrona pracy
Kursy Online -
Komputerowe wspomaganie projektowania (ZI, niestacjonarne - online - 2022/2023)
Kursy OnlineLaboratorium (dla kierunku Zarządzanie inżynierskie 2 semestr) ma na celu naukę projektowania z wykorzystaniem specjalistycznego oprogramowania klasy CAD.
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Zarządzanie Eksploatacją Systemów Technicznych NSTAC, sem. letni 18/19
Kursy OnlineZarządzanie Eksploatacją Systemów Technicznych, kierunek Zarządzanie Inżynierskie, studia niestacjonarne, sem. 6
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Komputerowe wspomaganie projektowania (ZI, niestacjonarne 2022/2023)
Kursy OnlineLaboratorium (dla kierunku Zarządzanie inżynierskie 2 semestr) ma na celu naukę projektowania z wykorzystaniem specjalistycznego oprogramowania klasy CAD.
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Komputerowe wspomaganie projektowania - st. stacjonarne, 2022/2023
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Ergonomia i ochrona pracy STAC, sem. zimowy 19/20
Kursy OnlineErgonomia i ochrona pracy, kierunek Zarządzanie inżynierskie, studia stacjonarne, sem. 5
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Ergonomia i ochrona pracy NIEST., sem. letni 2018/2019
Kursy OnlineErgonomia i ochrona pracy, kierunek Zarządzanie inżynierskie, studia niestacjonarne, sem. 6
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Ergonomia techniczna 2023/2024
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Ergonomia techniczna NIEST. 2023/2024
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Zdolni z Pomorza 2019/20 - Kropki i kreski, czyli grafy i ich zastosowania
Kursy OnlineCel kursu: Celem kursu jest wprowadzanie uczniów w świat grafów i zapoznanie ich z praktycznymi zastosowaniami teorii grafów. Opis kursu: Dawno temu Leonard Euler, jadąc do Petersburga, zatrzymał się po drodze w Królewcu. Tam zainteresował go problem, nad którym, jak wieść niesie, głowili się mieszkańcy tego miasta: czy da się przespacerować po Królewcu tak, aby każdy z jego siedmiu mostów przejść dokładnie raz? Euler podszedł...
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Complex Root Finding Algorithm Based on Delaunay Triangulation
PublikacjaA simple and flexible algorithm for finding zeros of a complex function is presented. An arbitrary-shaped search region can be considered and a very wide class of functions can be analyzed, including those containing singular points or even branch cuts. The proposed technique is based on sampling the function at nodes of a regular or a self-adaptive mesh and on the analysis of the function sign changes. As a result, a set of candidate points...
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Electrochemicalsynthesis of 3D nano-/micro-structured porous polypyrrole
PublikacjaIn this work, electrosynthesis of electroactive, 3D nano-/micro-structured porous polypyrrole film is presented. The PPy film was synthesized potentiostatically in a one-step process from aqueous solution of pyrrole and lithium perchlorate. The growth mechanism of such structure included: the formation of typical globular PPy film, followed by the formation of the PPy fibers, which then took part in the formation of 3D highly porous...
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Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity
PublikacjaIn the last few years,increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory. There are several antifungal compounds whichare highly effective in some cases, however, they have limitations in usage: Nephrotoxicity and other adverse effects. In addition, the frequent use of available fungistatic drugs promotes drug resistance....
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Elicitation strategies for the improvement of essential oil content in Rhododendron tomentosum (Ledum palustre) bioreactor-grown microshoots
PublikacjaRhododendron tomentosum Harmaja, previously Ledum palustre L., is a fragrant plant growing in swampy areas, which is characterized by well-known repellent properties and the anti-arthritic potential. In the present study, R. tomentosum microshoots cultivated in RITA® bioreactor, providing the alternative, environment-independent source of the valuable essential oil, were treated for 7 days with copper and nickel salts, methyl jasmonate,...
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The Substantial Improvement of Amphotericin B Selective Toxicity Upon Modification of Mycosamine with Bulky Substituents
PublikacjaAbstract: Background: It is assumed that the unfavorable selective toxicity of an antifungal drug Amphotericin B (AmB) can be improved upon chemical modification of the antibiotic molecule. Objective: The aim of this study was verification of the hypothesis that introduction of bulky substituents at the amino sugar moiety of the antibiotic may result in diminishment of mammalian vitro toxicity of thus prepared AmB derivatives. Methods:...
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The effect of nanoparticles size on photocatalytic and antimicrobial properties of Ag-Pt/TiO2 photocatalysts
PublikacjaAg-Pt-modified TiO2 nanocomposites were synthesized using the sol–gel method. Bimetallic modified TiO2 nanoparticles exhibited improved photocatalytic activity under visible-light irradiation, better than monometallic Ag/TiO2 and Pt/TiO2 nanoparticles (NPs). All modified powders showed localized surface plasmon resonance (LSPR) in visible region. The photocatalysts’ characteristics by X-ray diffractometry (XRD), scanning transmission...
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Seasonal Patterns and Trends in Dermatoses in Poland
PublikacjaThe amount of data available online is constantly increasing, including search behavior and tracking trends in domains such as Google. Analyzing the data helps to predict patient needs and epidemiological events more accurately. Our study aimed to identify dermatology-related terms that occur seasonally and any search anomalies during the SARS-CoV-2 pandemic. Methods: The data were gathered using Google Trends, with 69 entries...
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Long range molecular dynamics study of interactions of the eukaryotic glucosamine-6-phosphate synthase with fructose-6-phosphate and UDP-GlcNAc
PublikacjaGlucosamine-6-phosphate synthase (EC 2.6.1.16) is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. The final product of this pathway, uridine 5 diphospho Nacetyl- d-glucosamine (UDP-GlcNAc), is an essential substrate for assembly of bacterial and fungal cell walls. Moreover, the enzyme is involved in phenomenon of hexosamine induced insulin resistance in type II diabetes, which...
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Kazi Mohiuddin PhD Candidate
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Moizuddin S. Khaja Doctoral Candidate
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Paweł Dereszewski PhD Candidate
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Frank Llovera phd candidate
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Salome Khinikadze PhD candidate
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Etienne Gatera ph.D Candidate
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On the rising extra storage capacity of ultra-small Fe3O4particles functionalized with HCS and their potential as high-performance anode material for electrochemical energy storage
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Global Complex Roots and Poles Finding Algorithm Based on Phase Analysis for Propagation and Radiation Problems
PublikacjaA flexible and effective algorithm for complex roots and poles finding is presented. A wide class of analytic functions can be analyzed, and any arbitrarily shaped search region can be considered. The method is very simple and intuitive. It is based on sampling a function at the nodes of a regular mesh, and on the analysis of the function phase. As a result, a set of candidate regions is created and then the roots/poles are verified...
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Data from the Survey on Entrepreneurs’ Opinions on Factors Determining the Employment of the Gdańsk University of Technology Graduates
PublikacjaThe dataset includes data from a survey on factors determining the employment of the Gdańsk University of Technology (Gdańsk Tech) graduates’ in the opinion of entrepreneurs. The survey was conducted in 2017. The research sample included 102 respondents representing various firms from the Pomeranian Voivodeship, Poland. The study concerned i.a. factors determining the decision to hire a candidate, methods of recruiting employees,...
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Optimization of a Fabry-Perot Sensing Interferometer design for an optical fiber sensor of hematocrit level
PublikacjaContinuous measurement of the hemato crit level in blo o d can p otentially b e p erformed using optical bre sensors. The FabryPerot interferometric sensors are a promising candidate in this application. The most imp ortant step in the design of the sensor is design of the sensing interferometer. Adequate cavity length and high interference contrast are two most imp ortant requirements in this application. The design metho d of...
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Sensitivity of entanglement decay of quantum-dot spin qubits to the external magnetic field
PublikacjaWe study the decay of entanglement of quantum-dot electron-spin qubits under hyperfine-interaction-mediated decoherence.We show that two-qubit entanglement of a single entangled initial state may exhibit decay characteristic of two disentanglement regimes in a single sample, when the externalmagnetic field is changed. The transition is manifested by the suppression of time-dependent entanglement oscillations which are superimposed...
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Postulates for measures of genuine multipartite correlations
PublikacjaA lot of research has been done on multipartite correlations. However, it seems strange thatthere is no denition of so called genuine multipartite correlations. In this paper we propose threereasonable postulates which each measure or indicator of genuine multipartite correlations (or gen-uine multipartite entanglement) should satisfy. We also introduce degree of correlations which givespartial characterization of multipartite...
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Identification and cloning of C. albicans SC5314 genes encoding L-methionine biosynthetic pathway enzymes.
Dane BadawczeEnzymes of fungal L-methionine biosynthetic pathway: homoserine O-acetyltransferase (Met2p), O-acetylhomoserine sulfhydrylase (Met15p) and cystathionine-γ-synthase (Str2p) could be exploited as molecular targets for antifungal chemotherapy. The goal of the study was to identify and clone genes encoding mentioned above enzymes. MET2, MET15 and STR2 genes...
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Impact of Microphytobenthos Photosynthesis on the Characteristics of the Echo Signal from Baltic Sandy Sediments
PublikacjaThe understanding the influence of biological processes on the characteristics of the signals backscattered by the sea floor is crucial in the development of the hydroacoustical benthic habitat classification techniques. The impact of the microphytobenthos photosynthesis on the acoustical backscattering properties of the Atlantic sandy sediments was previously demonstrated by Holliday et al. (2004) and Wildman and Huettel (2012). To...
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Elucidating photoluminescent properties of Eu‐doped Ca–Al–Si–O(–N) glasses and the local structures of Eu ions
PublikacjaEuropium (Eu) ion–doped luminescent materials have attracted considerable attention for their numerous optical applications. Eu-doped Ca–Al–Si–O(–N) glasses were synthesized from a mixture of oxynitride glasses and Eu2O3 powder using a standard melt-quenching technique in a radiofrequency furnace. The source Eu trivalent ions primarily changed to Eu2+ during melting, and the ratio of Eu2+ ions increased with an increase in Eu content...
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Multimodal Genetic Algorithm with Phase Analysis to Solve Complex Equations of Electromagnetic Analysis
PublikacjaIn this contribution, a new genetic-algorithm-based method of finding roots and poles of a complex function of a complex variable is presented. The algorithm employs the phase analysis of the function to explore the complex plane with the use of the genetic algorithm. Hence, the candidate regions of root and pole occurrences are selected and verified with the use of discrete Cauchy's argument principle. The algorithm is evaluated...
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Functional properties of Cornelian cherry (Cornus mas L.): a comprehensive review
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Witold Parteka Dr
OsobyWykształcenie: Uniwersytet Gdański - Wydział Filologiczno-Historyczny – kierunek historia specjalność nauczycielska – dyplom (20 czerwiec 1997) – mgr historii Akademia Pomorska w Słupsku Wydział Filologiczno-Historyczny, Instytut Historii –– 21 październik 2009 - dr nauk humanistycznych w zakresie historii. Temat doktoratu: Szkolnictwo oficerskie Polskiej Marynarki Handlowej w latach 1945-1968 Zainteresowania badawcze: historia...
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Dziedzictwo kulturowe Gdańska. Zespół śródmiejski a miejska polityka historyczna
PublikacjaAktualna miejska polityka historyczna Gdańska skupia się wokół realizacji dwóch najważniejszych przedsięwzięć muzealnych, mających stać się swoistą materializacją jego dziedzictwa kulturowego. U jej podstaw leży zarysowana z europejskiej perspektywy narracja oparta na dwóch wielkich wydarzeniach xx wieku, która wydaje się jednak nie uwzględniać dziedzictwa kulturowego zapisanego w strukturze urbanistycznej zespołu śródmiejskiego...
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Enzymes of the lysine biosynthetic pathway as targets for antifungals ?
PublikacjaSystemic infections caused by human pathogenic fungi in immunocompromized patients continue to be one of the important clinical problems. Limited availability of safe and efficacious antifungal chemotherapeutics and emerging resistance to existing drugs stimulates search for novel molecular targets for antifungals. The α-aminoadipate pathway (AAP) of L-lysine biosynthesis is unique in fungi and thus has been so far considered...
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Nowe estrowe i amidowe pochodne inhibitorów syntazy glukozamino-6-fosforanu - synteza i aktywność biologiczna
PublikacjaPrzedmiotem rozprawy doktorskiej są modyfikacje chemiczne analogów glutaminy – kwasu N3-(4-metoksyfumaroilo)-S-2,3-diaminopropanowego (FMDP) oraz kwasu N3-[(E)-4-fenylo-4-okso-2-butenoilo]-S-2,3-diaminoaminopropanowego (BADP). Związki te są inhibitorami syntazy glukozamino-6-fosforanu i mimo ich silnych właściwości inhibicyjnych, nie wykazują zdolności do hamowania wzrostu drobnoustrojów. Brak aktywności przeciwdrobnoustrojowej...
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Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O-Acetyltransferase
PublikacjaDue to the apparent similarity of fungal and mammalian metabolic pathways, the number of established antifungal targets is low, and the identification of novel ones is highly desirable. The results of our studies, presented in this work, indicate that the fungal biosynthetic pathway of L-methionine, an amino acid essential for humans, seems to be an attractive perspective. The MET2 gene from Candida albicans encoding L-homoserine...
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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
PublikacjaSeven conjugates composed of well-known fluoroquinolone antibacterial agents, ciprofloxacin (CIP) or levofloxacin (LVX), and a cell-penetrating peptide transportan 10 (TP10-NH2) were synthesised. The drugs were covalently bound to the peptide via an amide bond, methylenecarbonyl moiety, or a disulfide bridge. Conjugation of fluoroquinolones to TP10-NH2 resulted in congeners demonstrating antifungal in vitro activity against human...