Filters
total: 6230
filtered: 4209
-
Catalog
- Publications 4209 available results
- Journals 77 available results
- Conferences 2 available results
- People 70 available results
- Inventions 5 available results
- Projects 6 available results
- Laboratories 3 available results
- Research Equipment 1 available results
- e-Learning Courses 386 available results
- Events 5 available results
- Open Research Data 1466 available results
Chosen catalog filters
displaying 1000 best results Help
Search results for: INTERNAL C SOURCE
-
Core–shell excitation of isoxazole at the C, N, and O K-edges – an experimental NEXAFS and theoretical TD-DFT study
PublicationThe near-edge X-ray absorption fine structure (NEXAFS) spectra of the gas-phase isoxazole molecule have been measured by collecting total ion yields at the C, N, and O K-edges. The spectral structures have been interpreted using time-dependent density functional theory (TD-DFT) with the short-range corrected SRC2-BLYP exchange–correlation functional. Experimental and calculated energies of core excitations are generally in good...
-
Sea spray as a secondary source of chlorinated persistent organic pollutants? - Conclusions from a comparison of seven fresh snowfall events in 2019 and 2021
PublicationSecondary sources of persistent organic pollutants (POPs) gain in importance worldwide as primary sources decline. In this work, we aim to determine whether sea spray may be a secondary source of chlorinated POPs to the terrestrial Arctic, since a similar mechanism was proposed there only for the more water-soluble POPs. To this end, we have determined polychlorinated biphenyls and organochlorine pesticides concentrations in fresh...
-
Molecular Structures of the Phospha-Wittig Reaction Intermediate: Initial Step in the Synthesis of Compounds with a C═P–P Bond as Products in the Phospha-Wittig Reaction
PublicationThe phospha-Wittig reactivity ofβ-diketiminate titanium(III) complexes with phosphanylphosphido ligands was investigated. The reactions of [MeNacNacTi(Cl){η2-P(SiMe3)-PtBu2}] and [MeNacNacTi(Cl){η2-P(SiMe3)-P(Ph)tBu}] with acetone conducted in toluene solution under mild conditions led to the phospha-Wittig intermediates [{(ArN=C(Me)CHC(Me)=NAr)(C(Me)2O}Ti(Cl){PtBu2-P(SiMe3)C(Me)2O}] (1) and [{(ArN=C(Me)CHC(Me)=NAr) (C-(Me)2O}Ti(Cl){P(Ph)tBu-P(SiMe3)C(Me)2O}]...
-
Replication of hepatitis C virus in peripheral blood mononuclear cells in patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin
Publication -
Hydroxyl and sulfate radical-based degradation of ciprofloxacin using UV-C and/or Fe2+-catalyzed peroxymonosulfate: Effects of process parameters and toxicity evaluation
PublicationCiprofloxacin (CIP) is a valuable antibiotic and discharged in huge quantities in aquatic environment. Different •OH and SO4•−-based advanced oxidation technologies (AOTs), e.g., Fe2+/PMS, UV-C/PMS, and UV-C/Fe2+/PMS are developed for treatment of CIP. The removal of CIP by Fe2+/PMS, UV-C/PMS and UV-C/Fe2+/PMS was 63, 77, and 87 %, respectively, under identical conditions which showed better performance of UV-C/Fe2+/PMS. The UV-C/Fe2+/PMS...
-
Efektywna warstwa pośrednicząca dla obliczeń typu master-slave w środowisku C++/MPI
PublicationPokazano, jak dla wysokowydajnościowego algorytmu pisanego w modelu master-slave w języku C++ i spełniającego pewne ograniczenia można napisać i wykorzystać warstwę komunikacyjną zupełnie oddzielającą kod odpowiedzialny za komunikację od kodu odpowiedzialnego za dzie-dzinę problemową. Przedstawiona zostaje specyfkacja wymagań, jakie powinien spełniać hipotetyczny system rozproszony oraz warstwa komunikacyjna, a także wymagania...
-
Antitumor 1-nitroacridine derivative C-1748, induces apoptosis, necrosis or senescence in human colon carcinoma HCT8 and HT29 cells.
PublicationC-1748 jest związkiem oddziaływującym z DNA i potencjalnym związkiem przeciwnowotworowym szczególnie wobec nowotworów prostaty i jelita grubego przeszczepialnych na myszach.W pracy badano odpowiedź komórek nowotworowych HCT8 i HT29 na działanie pochodnej C-1748, w stężeniach biologicznie istotnych (EC90). Analiza cyklu komórkowego linii HCT8 pokazała, że związek powoduje wzrost frakcji sub-G1, świadczący o apoptozie tych komórek...
-
Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells
PublicationW przedstawionych badaniach określano mechanizm śmierci komórkowej indukowanej przez imidazoakrydon C-1311 (Symadex) w komórkach HT-29 ludzkiego raka jelita grubego, które wykazywały szczególną wrażliwość na ten związek w eksperymentalnych modelach in vitro i in vivo. Przy stężeniu odpowiadającemu dawce IC99, związek powodował zahamowanie progresji cyklu komórkowej w fazie S po czym następował blok w fazie G2. Po czasach 48-96...
-
Therapeutic targeting of cathepsin C: from pathophysiology to treatment
Publication -
Decymator do przetwornika A/C typu ä(delta)
PublicationArtykuł opisuje projekt decymatora wykorzystywanego w przetworniku analogowo-cyfrowym typu ä(trójkt). Zaprojektowana struktura została zasymulowana zza pomocą programu MATLAB. Rozwijając architekturę decymatora szczególny nacisk został położony na minimalizację pobieranej mocy.
-
Blue-berried honeysuckle a promising cancer preventing fruit; Polish genotypes as a source of bioactive phytochemicals
PublicationFrom the ancient times, plants containing health-oriented compounds in their matrices are used in the treatment of different complaints and diseases. One of these groups are plant secondary metabolites (PSM), especially phenolic compounds, terpenes and terpenoids. A large number of PSM exhibit cytotoxicity against a variety of tumor cells, as well as cancer preventive and anticancer efficacy in preclinical animal models. For this...
-
Induction of unique structural changes in guanine-rich DNA regions by the triazoloacridone C-1305, a topoisomerase II inhibitor with antitumor activities.
PublicationCelem pracy było scharakteryzowanie odziaływania związku C-1305 z DNA w porównaniu do innych inhibitorów topoizomerazy II. Badania pokazują, że C-1305 odziaływuje preferencyjnie z parami CG, interkaluje do DNA i zaburza sąsiednie otoczenie w bardzo charakterystyczny sposób, który nie został zaobserwowany u pozostałych 22 badanych związków.
-
Molecular docking studies towards development of novel Gly-Phe analogs for potential inhibition of Cathepsin C (dipeptidyl peptidase I).
PublicationCathepsin C is a cysteine protease required for activation of various pro-inflammatory serine proteases and, essentially, is of interest as a therapeutic target. Cathepsin C coordinate system was employed as a model to study the interaction of some already available inhibitors of Cathepsin C. Compounds containing Gly-Phe fragment with functional groups at its ends were designed by knowledge based approach. Using AutoDock and...
-
2-Ethylphenyl acridine-9-carboxylate and 2,5-dimethylphenyl acridine-9-carboxylate
PublicationMetodą rentgenowskiej analizy strukturalnej oznaczono struktury estrów: trójskośnego 2-etylofenylowego oraz jednoskośnego 2,5-dimetylofenylowego kwasu akrydyno-9-karboksylowego. Oba związki w kryształach tworzą układy oddziaływań typu C-H...π oraz oddziaływań dyspersyjnych.
-
Field Cultivation and in vitro Cultures, Root-Forming Callus Cultures and Adventitious Root Cultures, of Panax quinquefolium as a Source of Ginsenosides
Publication -
Przemiany metaboliczne in vitro przeciwnowotworowej pochodnej imidazoakrydonu, C-1311, i jej wpływ na aktywność wybranych izoenzymów cytochromu P450
PublicationPrzedmiotem badań przedstawionych w niniejszej pracy jest aktywna przeciwnowotworowo pochodna należąca do grupy imidazoakrydonów, tj. C-1311, i jej analog 8-metoksylowy, związek C-1330, zsyntetyzowane w Katedrze Technologii Leków i Biochemii Politechniki Gdańskiej. Wstępne badania wykazały brak wyraźnej reaktywności C-1311 i C-1330 wobec wybranych rekombinantowych ludzkich izoenzymów cytochromu P450,...
-
Antitumor triazoloacridinone C-1305 as a potent FLT3 tyrosine kinase inhibitor in human acute myeloid leukemia (AML) cells.
PublicationJednym z defektów molekularnych u pacjentów z ostrą białaczką szpikową (AML) jest konstytutywna aktywacja receptoroweej kinazy tyrozynowj FLT3.Najczęstszą mutacją genu kodującego FLT3 jest wewnętrzna tandemowa duplikacja ITD we fragmencie okołobłonowym receptora. W pracy zbadano, czy przeciwnowotworowy triazoloakrydon C-1305 może być inhibitorem kinazy tyrozynowej FLT3. Badania przeprowadzono na dwóch liniach komórkowych białaczek...
-
Control Strategy of a Five-Phase Induction Machine Supplied by the Current Source Inverter With the Third Harmonic Injection
PublicationIn the five-phase induction machine (IM), it is possible to better use the electromagnetic circuit than in the three-phase IM. This requires the use of an adequate converter system which will be supplied by an induction machine. The electric drive system described, in this article, includes the five-phase induction machine supplied by the current source inverter (CSI). The proposed novelty—not presented previously—is the control...
-
<title>Fiber-optic low-coherence tomography system for visualization of internal structure of ceramic materials</title>
Publication -
Problems of modelling toxic compounds emitted by a marine internal combustion engine for the evaluation of its structure parameters
PublicationThe paper presents the possibility of using an analytical study of the engine exhaust ignition to evaluate the technical condition of the selected components. Software tools available for the analysis of experimental data commonly use multiple regression model that allows the study of the effects and iterations between model input quantities and one output variable. The use of multi-equation models gives a lot of freedom in the...
-
The Impact of Internal Compensatory Mechanisms on Musculoskeletal Pain in Elite Polish Sitting Volleyball Players – A Preliminary Study
Publication -
Phosphorus pools and internal loading in a eutrophic lake with gradients in sediment geochemistry created by land use in the watershed
Publication -
Influence of different types of the internal system of the ballistic helmet shell on the thermal insulation measured by a manikin headform
Publication -
Increasing Energy Efficiency and Productivity of the Comminution Process in Tumbling Mills by Indirect Measurements of Internal Dynamics—An Overview
Publication -
Topological model of aptitude of the measurement circuits of main subassemblies of an internal combustion engine crankshaft-piston assembly
PublicationThe paper presents a topological model allowing to determine the probability of aptitude of the diagnosing system (SDG) individual measuring circuits and also to determine to what degree they influence the assessment of the technical condition of an arbitrary main subassembly of crankshaft-piston assemblies as a diagnosed system (SDN).
-
Diagnostic testing of marine propulsion systems with internal combustion engines by means of vibration measurement and results analysis
PublicationIn this paper selected issues concerning vibration diagnosis of the mechanical system within marine propulsion units have been presented, carried out on the basis of experimental examinations of a real object in which an exceedance of the allowable vibration’s level had been observed. Used diagnosing system has been characterised. A procedure of longitudinal and transverse vibrations shaft lines of the mechanical system within...
-
Analysis of the internal shell stability of the cylindrical vertical double-shell tank under the condition of the hydrostatic test
PublicationUtrata stateczności płaszcza wewnętrznego w pionowym stalowym zbiorniku może wystąpić jeżeli podczas próby wodnej słup wody w przestrzeni międzypłaszczowej będzie miał większą wysokość niż w zbiorniku wewnętrznym. W artykule przeprowadzono analizę jaka różnica poziomów wody podczas próby wodnej może zagrażać stateczności płaszcza wewnętrznego w zbiorniku o pojemności od 10000 m3 do 100000 m3.
-
Stability analysis of the internal cylindrical shell wall of a vertical double shell tank under a water test.
PublicationPrzedstawiono analizę zagrożenia stateczności lokalnej płaszcza wewnętrznego przy różnicy poziomów wody w zbiorniku wewnętrznym i przestrzeni międzypłaszczowej podczas próby wodnej zbiornika. Podano krytyczne różnice poziomów wody dla typowych zbiorników o pojemności od 10 000 do 100 000 m3.
-
Fabrication of the cross-linked PVA/TiO2/C nanocomposite membrane for alkaline direct methanol fuel cells
PublicationA crosslinked Poly(vinyl alcohol) based composite membrane was developed through a phase inversion process for use in alkaline direct methanol fuel cells (ADMFCs). The titanium dioxide (TiO2) and carbon nanoparticles (NPs) have been incorporated into the PVA polymer matrix to improve the mechanical and thermal properties. The membrane samples were further modified with maleic acid, a carboxylic acid acting as the cross-linker,...
-
Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7
PublicationBackground The compound 9-(2′-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), the promising antitumor agent developed in our laboratory was determined to undergo phase I metabolic pathways. The present studies aimed to know its biotransformation with phase II enzymes – UDP-glucuronosyltransferases (UGTs) and its potential to be engaged in drug-drug interactions arising from the modulation of UGT activity. Methods UGT-mediated...
-
Electrochemistry meets enzymes: Investigation of the biotransformation pathway of C-1311 based on electrochemical simulation in comparison to in vitro methods.
PublicationThe knowledge of the metabolic pathways and the biotransformation of new drugs is one of the major challenges in pharmaceutical research. It is crucial for elucidation of degradation routes of the new biologically active compounds, especially in the area of possible toxicity. Conventional in vitro drug metabolism studies are based on incubating drug candidate with e.g. hepatocytes or, most importantly, liver cell microsomes and...
-
Changes on the Surface of the SiO2/C Composite, Leading to the Formation of Conductive Carbon Structures with Complex Nature of DC Conductivity
PublicationSol–gel layers have been the subject of many studies in recent decades. However, very little information exists about layers in which carbon structures are developed in situ. Using the spin-coating method, we obtained thin iron-doped SiO2/C composite films. The results of Raman spectroscopy showed that our samples consisted of graphitic forms and polymers. The latter’s contribution decreases with rising temperature. FTIR and EDS...
-
The effect of microemulsion composition on the morphology of Pd nanoparticles deposited at the surface of TiO2 and photoactivity of Pd-TiO2
PublicationA series of microemulsion (ME) system, constituted by different water to surfactant molar ratios (Wo) and oil to surfactant mass ratios (S), have been applied for Pd-TiO2 preparation. The effect of ME properties on the morphology of Pd nanoparticles formed at TiO2 surface and an effect of Pd size and distribution on the surface and photocatalytic properties of Pd-TiO2 were investigated. Microemulsion systems were characterized...
-
Nuclear Power Plant Steam Turbine - Modeling for Model Based Control Purposes
PublicationThe nature of the processes taking place in a nuclear power plant (NPP) steam turbine is the reason why their modeling is very difficult, especially when the model is intended to be used for on-line optimal model based process control over a wide range of operating conditions, caused by changing electrical power demand e.g. when combined heat and power mode of work is utilized. The paper presents three nonlinear models of NPP steam...
-
Morphometric evaluation of the delayed cerebral arteries response to acetazolamide test in patients with chronic carotid artery stenosis using computed tomography angiography
PublicationBackground: The evidence accumulates that the response to acetazolamide test is delayed on the ipsilateral side to stenosis. However, the effect of acetazolamide beyond 30 minutes after acetazolamide administration remains unknown. The aim of this study was to assess the diameters of: anterior cerebral arteries (ACAs), middle cerebral arteries (MCAs) and posterior cerebral arteries (PCAs) before and 60 minutes after the acetazolamide...
-
Exploring the factor structure and the validity of the abbreviated Basic and Earning Self-Esteem Scales
PublicationThe original longer versions (Forsman & Johnson, 1996) and abbreviated versions of the Basic and Earning Self-Esteem Scales have been used in clinical and non-clinical settings, but little is known about the factor structure and the validity of these scales in their abbreviated forms. The original longer versions of the scales comprise several dimensions, but both abbreviated versions of the scales have been interpreted as if they...
-
Evaluation of polycaprolactone as a new sorbent coating for determination of polar organic compounds in water samples using membrane–SPME
PublicationCommercially available solid-phase microextraction fibers used for isolation of polar analytes are based on the adsorption phenomenon. In consequence, typical limitations bonded with analytes displacement and matrix effects are very frequent. In the present study, alternative solution is described. Polycaprolactone (PCL) was used for the first time as sorbent to isolate polar organic compounds from water samples using the membrane–solid-phase...
-
Comparison of classical and modern approach of determination of highly polar compounds by High Performance Liquid Chromatography coupled with Tandem Mass Spectrometry
PublicationAbstract: Sugars and sugar alcohols are known as highly polar compounds. Four analytes were taken into consideration for comparison of classical and modern approach of separation of highly polar substances. Mannitol was chosen as an example of simple sugar alcohol, sucrose and lactulose as examples of disaccharides and structural isomers, raffinose as an example of complex trisaccharide. Raffinose was also used as internal standard...
-
Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals
PublicationBackground: Recently, we described a model system which included corrections of high-resolution computedtomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM).Objective: To verify the clinical application of ASM by comparing bronchial measurements obtained bymeans of the traditional eye-driven method, subpixel method alone and ASM in a group comprised ofbronchial asthma patients and healthy individuals.Methods:...
-
Innovative activity of SMEs In Poland
PublicationInnovative activity of enterprises is determined by many factors. On one hand, these are external factors creating a sort of innovative climate in the economy, on the other hand - there are many internal factors stimulating or reducing the intensity of innovative activities. What influences the innovativeness of enterprises is the effectiveness of the system supporting innovations, which was stated by for example Pyciński and Żołnierski...
-
Multiprocessor Implementation of Parallel Multiobjective Genetic Algorithm for Optimized Allocation of Chlorination Stations in Drinking Water Distribution System a New Water Quality Model Approach
PublicationThe Critical Infrastructure Systems (CISs) have received in recent years a considerable attention due to their heavy impact on sustainable development of modern societies. Most CISs may be classied as large scale complex systems of network structure, in uenced by strong interactions form the surrounding environment, internal and external interconnections. The later is a result of inter-CIS dependencies. The control, monitoring...
-
Low-Loss 3D-Printed Waveguide Filters Based on Deformed Dual-Mode Cavity Resonators
PublicationThis paper introduces a new type of waveguide filter with smooth profile, based on specially designed dual-mode (DM) cavity resonators. The DM cavity design is achieved by applying a shape deformation scheme. The coupling between the two orthogonal cavity modes is implemented by breaking the symmetry of the structure, thus eliminating the need for additional coupling elements. The modes operating in the cavity are carefully analyzed...
-
MSP for port areas – To what extent should we interfere with governance of ports’ waters? Case study of Polish seaports
PublicationThe EU MSP Directive imposed the requirement to develop plans for all water areas under the jurisdiction of an EU country by the end of March 2021. Poland is the only country in the Baltic Sea Region whose maritime administration has decided to elaborate detailed maritime spatial plans for port waters. The aim of the paper is to draw conclusions from the work carried out so far on the MSP for Polish port water areas. For this purpose,...
-
Assessment of Sewage Molecular Markers: Linear Alkylbenzenes in Sediments of an Industrialized Region in Peninsular Malaysia
PublicationIn this study, the use of linear alkylbenzenes (LABs) was employed to pinpoint the sources of human activity that cause detrimental impacts on the coastal environment and river ecosystems. LABs were detected using GC–MS in sediment samples assembled from Kim Kim River (KKR) and the Port Dickson coast (PDC). To assess the significance of variations in the distribution and concentrations of LABs across the sampling sites, this study...
-
Application of Text Analytics in Public Service Co-Creation: Literature Review and Research Framework
PublicationThe public sector faces several challenges, such as a number of external and internal demands for change, citizens' dissatisfaction and frustration with public sector organizations, that need to be addressed. An alternative to the traditional top-down development of public services is co-creation of public services. Co-creation promotes collaboration between stakeholders with the aim to create better public services and achieve...
-
Potentiometric Solid-Contact Ion-Selective Electrode for Determination of Thiocyanate in Human Saliva
PublicationA new solid-contact potentiometric ion-selective electrode for the determination of SCN− (SCN-ISE) has been described. Synthesized phosphonium derivative of calix[4]arene was used as a charged ionophore. The research included selection of the ion-selective membrane composition, determination of the ISEs metrological parameters and SCN-ISE application for thiocyanate determination in human saliva. Preparation of the ISEs included...
-
Investigating the Effects of Geometrical Parameters of Re-Entrant Cells of Aluminum 7075-T651 Auxetic Structures on Fatigue Life
PublicationIn this study, the effects of two geometrical parameters of the re-entrant auxetic cells, namely, internal cell angle (θ) and H/L ratio in which H is the cell height, and L is the cell length, have been studied on the variations of Poisson’s ratio and fatigue life of Aluminum 7075-T6 auxetic structures. Five different values of both the H/L ratio and angle θ were selected. Numerical simulations and fatigue life predictions have...
-
Characterization of Arctic Driftwood as Naturally Modified Material. Part 1: Machinability
PublicationArctic driftwood has reached the coast of Iceland for centuries. This material was used by the inhabitants of the island as a building material for houses, boats, churches and pasture fences. Nowadays, the driftwood is used in the furniture industry, for the finishing of internal and external walls of buildings and also by artists. The properties of driftwood differ to that of original resource due the long-term effects of exposure...
-
Mechanical Properties and Residual Stress Measurements of Grade IV Titanium and Ti-6Al-4V and Ti-13Nb-13Zr Titanium Alloys after Laser Treatment
PublicationNowadays, surface engineering focuses on research into materials for medical applications. Titanium and its alloys are prominent, especially Ti-6Al-4V and Ti-13Nb-13Zr. Samples made of pure grade IV titanium and the titanium alloys Ti-6Al-4V and Ti-13Nb-13Zr were modified via laser treatment with laser beam frequency f = 25 Hz and laser beam power P = 1000 W during a laser pulse with duration t = 1 ms. Subsequently, to analyze...
-
Anionic states of C6Cl6 probed in electron transfer experiments
PublicationThis is the first comprehensive investigation on the anionic species formed in collisions of fast neutral potassium (K) atoms with neutral hexachlorobenzene (C6Cl6) molecules in the laboratory frame range from 10 up to 100 eV. In such ion-pair formation experiments, we also report a novel K+ energy loss spectrum obtained in the forward scattering giving evidence of the most accessible electronic states. The vertical electron affinity...