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Search results for: growth inhibition potential
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Novel and effective synthesis protocol of AgNPs functionalized using L-cysteine as a potential drug carrier
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Zeta potential and effective diameter of n-tetradecane emulsions in n-propanol solutions and in the presence of lysozyme
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Apolipoprotein E ( ApoE ) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?
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Investigating the potential of CuSCN as hole transport layer for perovskite solar cells for applications in indoor photovoltaics
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A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
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Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment
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A Holistic Approach to Determining Stereochemistry of Potential Pharmaceuticals by Circular Dichroism with β-Lactams as Test Cases
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ICTP concentration in cervical-vaginal fluid as a potential marker of membrane collagen degradation before labor
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Changes in the Mechanical Properties of Alginate-Gelatin Hydrogels with the Addition of Pygeum africanum with Potential Application in Urology
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Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis [Corrigendum]
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Harmonic analysis of the current of an electric system simulating the electrode process in conditions of linearly changing potential
PublicationAnalizowany był prąd elektrycznego modelu symulującego pierwszorzędową reakcję elektrodową zachodzącą w warunkach liniowo zmieniającego się potencjału z nałożonym sygnałem sinusoidalnym. Pokazano, że transformacja Fouriera nie odzwierciedla zmian amplitudy składowych komponentów w funkcji potencjału. Także matematycznie wykazano, że zastosowanie transformacji Gabora do analizy spektralnej pozwala uzyskać poprawną dekompozycję częstotliwościową....
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Chemometric Assessment and Best-Fit Function Modelling of the Toxic Potential of Selected Food Packaging Extracts
PublicationFood packaging materials constitute an ever more threatening environmental pollutant. This study examined options to specifically assess the ecotoxicity of packaged wastes, such as cans, subjected to various experimental treatments (in terms of extraction media, time of exposure, and temperature) that imitate several basic conditions of the process of food production. The extracts were studied for their ecotoxicity with bioluminescent...
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Muramyl dipeptide-based analogs as potential anticancer compounds: Strategies to improve selectivity, biocompatibility, and efficiency
PublicationAccording to the WHO, cancer is the second leading cause of death in the world. This is an important global problem and a major challenge for researchers who have been trying to find an effective anticancer therapy. A large number of newly discovered compounds do not exert selective cytotoxic activity against tumorigenic cells and have too many side effects. Therefore, research on muramyl dipeptide (MDP) analogs has attracted interest...
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Renoprotective and Cardioprotective Potential of Moricandia sinaica (Boiss.) against Carbon Tetrachloride-Induced Toxicity in Rats
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Comparison of Cu1.3Mn1.7O4 spinels doped with Ni or Fe and synthesized via wet chemistry and solid-state reaction methods, designed as potential coating materials for metallic interconnects
PublicationThe influence of the method applied to synthesize Cu-Mn-O spinel was evaluated. The methods selected for the investigation were EDTA gel processes and solid-state reaction synthesis. From the obtained powders, sinters were prepared and assessed in terms of their properties as potential coating materials. Additionally, the influence of Ni and Fe dopants was evaluated. The results show that the EDTA gel processes method seems to...
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Estimation of autotrophic maximum specific growth rate constant-experience from the long-term operation of a laboratory-scale Sequencing Batch Reactor System
PublicationW pracy wykorzystano wyniki badań z długookresowej eksploatacji laboratoryjnego reaktora typu SBR do estymacji stałej szybkości przyrostu bakterii nitryfikacyjnych. Badania obejmowały zarówno pomiary empiryczne (doświadczenia przy niskim stosunku substratu do biomasy) oraz symulacje komputerowe. Do symulacji dynamicznych wykorzystano jedną wartość współczynnika = 1,2 1/d, pomimo różnych wartości mierzonych jednostkowych szybkości...
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Prenatal stress affects insulin-like growth factor-1 (IGF-1) level and IGF-1 receptor phosphorylation in the brain of adult rats
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Adaptation of phenol-degrading Pseudomonas putida KB3 to suboptimal growth condition: A focus on degradative rate, membrane properties and expression of xylE and cfaB genes
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Conformational latitude – activity relationship of KPPR tetrapeptide analogues toward their ability to inhibit binding of vascular endothelial growth factor 165 to neuropilin‐1
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Applicability of phenolic acids as effective enhancers of cocrystals solubility of methylxanthines
PublicationApplicability of phenolic acids as potential cocrystal formers for methylxanthine derivatives was analyzed both in terms of cocrystallization probabilities and solubility advantage. The cocrystal formation abilities were evaluated using mixing enthalpy estimated within the conductor like screening model for real solvents (COSMO-RS) framework. The solubility improvement of potential cocrystals was estimated by formulation of the...
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Mirosław Andrusiewicz prof. dr hab. n. med. i n. o zdr.
PeopleDiplomas, degrees conferred in specific areas ̶ Post-doctoral degree in medical sciences (doctor habilitated) (discipline: medical biology) December 4, 2017; Title of academic achievement: "Analysis of selected genes involved in the control of pathological changes in cells derived from internal female reproductive organs"; Poznan University of Medical Sciences, Faculty of Medicine II; re-viewers: Prof. Katarzyna Ziemnicka,...
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Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublicationNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
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[18F]Amylovis as a Potential PET Probe for β-Amyloid Plaque: Synthesis, In Silico, In vitro and In vivo Evaluations
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Potential clinical application of serum proteome mass spectrometry analyses in breast cancer patients diagnosis and management
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Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
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Fiber optic microsphere with a ZnO thin film for potential application in a refractive index sensor – theoretical study
PublicationOptical fiber sensors of refractive index play an important role in analysis of biological and chemical samples. This work presents a theoretical investigation of spectral response of a fiber optic microsphere with a zinc oxide (ZnO) thin film deposited on the surface and evaluates the prospect of using such a structure for refractive index sensing. A microsphere is fabricated by an optical fiber tapering method on the base of...
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Sporothrix schenckii: purification and partial biochemical characterisation of glucosamine-6-phosphate synthase, a potential antifungal target
PublicationW artykule opisano izolację i charakterystykę właściwości natywnego enzymu, syntazy GlcN-6-P z komórek dimorficznego grzyba patogennego Sporothrix schenckii. Masę cząsteczkową enzymu natywnego określono na 350 kDa, a enzymu zdenaturowanego na około 79 kDa, co sugeruje homotetrameryczną strukturę białka. Wartość punktu izoelektrycznego wyniosła 6,26; wyznaczono także parametry kinetyczne katalizowanej reakcji. Aktywność enzymu była...
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Variations in the near-surface atmospheric electric field at high latitudes and ionospheric potential during geomagnetic perturbations
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Sonochemical synthesis of rosuvastatin based novel 3-methyleneisoindolin-1-one derivatives as potential anticancer agents
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Effect of the Yerba mate (Ilex paraguariensis) brewing method on the content of selected elements and antioxidant potential of infusions
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Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge
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Antioxidant potential of various solvent extract from Morus alba fruits and its major polyphenols composition
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Identification of organic acids as potential biomarkers in the urine of autistic children using gas chromatography/mass spectrometry
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Immunoscore, circulating tumor cells and human-derived organoids as potential predictive tools in personalized cancer medicine
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Potential of bacteriocins from lab to improve microbial quality of dry-cured and fermented meat products [pdf]
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Applications of Cannabis Sativa L. in Food and Its Therapeutic Potential: From a Prohibited Drug to a Nutritional Supplement
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Phthalocyanine Derivatives Possessing 2-(Morpholin-4-yl)ethoxy Groups As Potential Agents for Photodynamic Therapy
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A Potential Relationship Between Estrogen Receptors Polymorphisms, Sperm Function and in vitro Fertilization Success: A Preliminary Study*
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Dendrimeric Sulfanyl Porphyrazines: Synthesis, Physico-Chemical Characterization, and Biological Activity for Potential Applications in Photodynamic Therapy
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Meat products Brassica exploiting anticarcinogenic potential of cabbage phytochemicals: Polish path to bio-inspired foods
PublicationBadania populacyjne ostatnich dwóch dziesięcioleci wskazują na sposób odżywiania jako jeden z głównych czynników zagrożenia chorobami cywilizacyjnymi, z nowotworami włącznie. W przypadku chorób nowotworowych głównym elementem diety sprzyjającej kancerogenezie jest czerwone mięso. Ze względu na wartość odżywczą i powszechność spożycia produktów mięsnych, poprawienie ich wartości żywieniowej staje się problemem o istotnym znaczeniu...
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Analysis of mixing rules for the Stillinger-Weber potential: a case study of Ge-Si interactions in the liquid phase
PublicationCiekły stop Ge_{0.25}Si_{0.75} symulowano metodą dynamiki molekularnej, przy użyciu potencjału Stillingera-Webera. Badano wpływ parametryzacji członu potencjału odpowiedzialnego za oddziaływania trójciałowe w trójkach nieidentycznych atomów na strukturę symulowanego stopu. Wpływ ten okazał się być znaczący.Zmiany w parametrach rzędu kilku procent skutkowały istotnymi różnicami w parowych funkcjach rozkładu, kątowych funkcjach rozkładu...
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Facile synthesis of porous iron oxide/graphene hybrid nanocomposites and potential application in electrochemical energy storage
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Novel electrogravimetric biosensors for the ultrasensitive detection of plasma matrix metalloproteinase-2 considered a potential tumor biomarker
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Investigating the potential influence of biochar and traditional organic amendments on the bioavailability and transfer of Cd in the soil–plant system
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Investigation of DPPC effect on SiO2 particles and in the presence of phospho(lipases) by zeta potential and effective diameter measurements
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Investigations of DPPC effect on Al2O3 particles in the presence of (phospho)lipases by the zeta potential and effective diameter measurements
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Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase
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Abdominoplasty Skin-Based Dressing for Deep Wound Treatment—Evaluation of Different Methods of Preparation on Therapeutic Potential
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Potential Saving of Antibiotics for Respiratory Infections in Several European Countries: Insights from Market Research Data
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