Search results for: mtDNA genome - Bridge of Knowledge

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Search results for: mtDNA genome

Search results for: mtDNA genome

  • MEDIA ARCHITECTURE AND INTERACTIVE ART INSTALLATIONS STIMULATING HUMAN INVOLVEMENT AND ACTIVITIES IN PUBLIC SPACES

    This paper examines the potential for media architecture and interactive art installations to stimulate human involvement and activities in public spaces. On the basis of theoretical approaches, case studies and interdisciplinary surveys, the paper provides insight into how screens projecting media and interactive installations in city spaces can inspire people to become active on many levels. The research is focused, both on temporary...

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  • Genetyka molekularna - wykład, WCh 2022/23, Biotechnologia II stopień - new

    e-Learning Courses
    • B. Zalewska-Piątek

    Celem kursu jest zapoznanie się z podstawowymi mechanizmami funkcjonowania genomów, regulacji ich aktywności i dziedziczenia, edycją genomu w oparciu o programowane nukleazy (system CRISPR-Cas i prime-editing), metodami wykorzystywanymi do analizy struktury, funkcji genów,  skutków zmian mutacyjnych oraz wyłączania ich aktywności (np. TargeTron gene nockout system) oraz  technikami in vitro wykorzystywanymi do wprowadzania biomolekuł...

  • Genetyka molekularna - wykład, WCh 2023/24, Biotechnologia II stopień

    e-Learning Courses
    • B. Zalewska-Piątek

    Celem kursu jest zapoznanie się z podstawowymi mechanizmami funkcjonowania genomów, regulacji ich aktywności i dziedziczenia, edycją genomu w oparciu o programowane nukleazy (system CRISPR-Cas i prime-editing), metodami wykorzystywanymi do analizy struktury, funkcji genów,  skutków zmian mutacyjnych oraz wyłączania ich aktywności (np. TargeTron gene nockout system) oraz  technikami in vitro wykorzystywanymi do wprowadzania biomolekuł...

  • Genetyka molekularna - wykład, WCh 2024/25, Biotechnologia II stopień

    e-Learning Courses
    • B. Zalewska-Piątek

    Celem kursu jest zapoznanie się z podstawowymi mechanizmami funkcjonowania genomów, regulacji ich aktywności i dziedziczenia, edycją genomu w oparciu o programowane nukleazy (system CRISPR-Cas i prime-editing), metodami wykorzystywanymi do analizy struktury, funkcji genów,  skutków zmian mutacyjnych oraz wyłączania ich aktywności (np. TargeTron gene nockout system) oraz  technikami in vitro wykorzystywanymi do wprowadzania biomolekuł...

  • Synovial sarcoma, NOS - Male, 33 - Tissue image [6300730028256791]

    Open Research Data

    This is the histopathological image of OTHER AND UNSPECIFIED PARTS OF MOUTH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Data on solutions of Hes1 system

    Open Research Data
    open access

    Hes1 protein (hairy and enhancer of split 1) belongs to the helix-loop-helix (bHLH) family of transcription proteins, i.e. DNA-binding proteins in the promoter region or in another region where regulation of transcription processes occurs.    The database collects data on solutions of the Hes1 systems with multiple binding sites and the dimer formation...

  • Decentralized energy systems. Social aspects of energy production and use (10h, 2 ECTS credits)

    e-Learning Courses
    • M. Galik
    • A. Klej
    • A. Augusiak

    The main aim of the course is to introduce students to the socio-political aspects of the decentralization of energy systems. The motivation behind these changes is not only due to technological developments or economic issues. The main driving force are wider social and political trends. Many energy supply projects that are being developed and implemented today assume an active role for consumers in energy production, who become...

  • Interactive Decision Making, Environmental Engineering, 2022/2023 (summer semester)

    e-Learning Courses
    • A. Jakubczyk-Gałczyńska
    • A. Siemaszko

    The course is designed for students of MSc Studies in Environmental Engineering Person responsible for the subject, carrying out lectures and tutorials: mgr inż. Agata.Siemaszko; agata.siemaszko@pg.edu.pl The person conducting the lectures and tutorials: dr inż. Anna Jakubczyk-Gałczyńska; anna.jakubczyk@pg.edu.pl The course provides students with knowledge on development and application of statisticalstrategic approach to decision...

  • Molecular and structural basis of inner core lipopolysaccharide alterations in Escherichia coli: incorporation of glucuronic acid and phosphoethanolamine in the heptose region.

    Publication

    - JOURNAL OF BIOLOGICAL CHEMISTRY - Year 2013

    It is well established that lipopolysaccharide (LPS) often carries nonstoichiometric substitutions in lipid A and in the inner core. In this work, the molecular basis of inner core alterations and their physiological significance are addressed. A new inner core modification of LPS is described, which arises due to the addition of glucuronic acid on the third heptose with a concomitant loss of phosphate on the second heptose. This...

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  • Virulence analysis and antibiotic resistance of Klebsiella pneumoniae isolates from hospitalised patients in Poland

    Publication
    • B. Kot
    • M. Piechota
    • P. Szweda
    • J. Mitrus
    • J. Wicha
    • A. Grużewska
    • M. Witeska

    - Scientific Reports - Year 2023

    Klebsiella pneumoniae (KP) is a nosocomial pathogen causing difficult-to-treat infections. The presence of virulence genes and antibiotic resistance of 109 KP isolates from hospitalized patients were investigated. Among them, 68.8% were multi-drug resistant (MDR) and 59.6% produced extended-spectrum beta-lactamases (ESBLs). Metallo-β-lactamases (MBLs) were produced by 22% of isolates (mainly from anus), including 16.5% of isolates...

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  • Active Dynamic Thermography imaging of wound healing processes in cardio surgery

    Publication

    - Year 2014

    The surgery is a branch of medicine, that is integrally connected to wounds. Despite using sterile tools and compliance with aseptic rolls, some of the surgery wounds become infected. In clinical practice there is a lack of cheap, objective methods and tools for quantitative definition and estimation of the surgery wound healing progress. This paper presents preliminary results of Active Dynamic Thermography (ADT) parametric imaging...

  • Determination of antibiotic residues in honey

    Honey produced by honeybees is a valuable food product. The presence of xenobiotics in honey may harm its quality and constitute a danger to human health. Antibiotics are commonly applied by beekeepers to eliminate disease among honeybees. Moreover, ubiquitous administration of antibiotics may cause bacteria to become resistant to many drugs and spread antibioticresistant strains of bacteria. Appropriate sample preparation and...

  • Selected organophosphorus compounds with biological activity. Applications in medicine

    The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...

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  • Peer assessment as a method for measuring harmful internet use

    Publication
    • W. W. Koczkodaj
    • A. Kowalczyk
    • M. Mazurek
    • W. Pedrycz
    • G. Redlarski
    • E. Rogalska
    • D. Strzałka
    • A. Szymańska
    • A. Wilinski
    • S. Xue

    - MethodsX - Year 2023

    Harmful Internet use (HIU) describes unintended use of the Internet. It could be both self-harm and harming others. Our research goal is to develop a more accurate method for measuring HIU by this novel peer assessment. As such, it may become, with our call for more research, a paradigm shift supplementing every rating scale or other type of Internet use assessment. In addition to classic statistical analysis, structural equations...

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  • The (over)touristification of European historic cities: a relation between urban heritage and short-term rental market demand

    Publication

    - Year 2023

    In this chapter, I wish to highlight the critical relationship between heritage management issues and building environment transformation. I argue that such a relationship is directly expressed through the tourism phenomenon, and it should be measured through the economic dimension of the short-term rental market, which introduces this rule of thumb: if there is a lack of demand, the brand of the city is weak; if there is too much...

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  • L’indistricabile intreccio. Imprese, imprenditori e regime fascista. (An Inextricable Intertwining. Companies, Entrepreneurs, and the Fascist Regime)

    Publication

    - Studi Storici - Year 2020

    The papers of this section analyse the relationships between the economic and business community and the fascist regime. Their aim is to refresh the interpretations that were established in the 1960s-1970s and remained undisputed in the decades thereafter, becoming a sort of mantra among Italian contemporary historians. The article presents the most relevant contributions of that historiographical season, explaining the reasons...

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  • Modified DNA polymerases for PCR troubleshooting

    PCR has become an essential tool in biological science. However, researchers often encounter problems with difficult targets, inhibitors accompanying the samples, or PCR trouble related to DNA polymerase. Therefore, PCR optimization is necessary to obtain better results. One solution is using modified DNA polymerases with desirable properties for the experiments. In this article, PCR troubleshooting, depending on the DNA polymerase...

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  • On the Origin of Protein Superfamilies and Superfolds

    Publication

    - Scientific Reports - Year 2015

    Distributions of protein families and folds in genomes are highly skewed, having a small number of prevalent superfamiles/superfolds and a large number of families/folds of a small size. Why are the distributions of protein families and folds skewed? Why are there only a limited number of protein families? Here, we employ an information theoretic approach to investigate the protein sequence-structure relationship that leads to...

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  • Ammonia amendment promotes high rate lactate production and recovery from semi-continuous food waste fermentation

    Publication
    • A. l. o. o. p. Zhang
    • X. Li
    • Y. He
    • X. Xu
    • H. Chen
    • A. Zhang
    • Y. Liu
    • G. Xue
    • J. Mąkinia

    - BIORESOURCE TECHNOLOGY - Year 2020

    In this study, a reliable approach using ammonia nitrogen was proposed to increase lactate production during semi-continuous food waste (FW) fermentation under mesophilic conditions. Both free ammonia nitrogen (FAN) and ammonium ion (NH4+-N) were present in mesophilic reactors, with a wide FAN/NH4+-N ratio variation due to the intermittent pH control. The investigation of responsible mechanisms revealed that the increased production...

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  • Evaluation of a Novel Approach to Virtual Bass Synthesis Strategy

    Publication

    - Year 2015

    The aim of this paper is to present a novel approach to the Virtual Bass Synthesis (VBS) strategy applied to portable computers. The developed algorithms involve intelligent, rule-based settings of bass synthesis parameters with regard to music genre of an audio excerpt and the type of a portable device in use. The Smart VBS algorithm performs the synthesis based on a nonlinear device (NLD) with artificial controlling synthesis...

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  • Charakterystyka oporności Klebsiella pneumoniae New Delhi na karbapenemy

    Publication

    Bakterie Klebsiella pneumoniae New Delhi, posiadające gen oporności na karbapenemy (blaNDM) zostały po raz pierwszy wyizolowane w 2008 roku w Szwecji od pacjenta wcześniej hospitalizowanego w Indiach. Bakterie te szybko rozprzestrzeniają się po całym świecie, a od 2011 roku występują również w Polsce. Stanowią one wysokie ryzyko epidemiologiczne, ponieważ gen oporności na karbapenemy przekazywany jest pomiędzy bakteriami poprzez...

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  • Pilot- scale plant for material recycling of whole waste tires

    Publication

    Continously growing demad for all kinds of vehicles and general tendency to regular exchange of tires are causing growth of scrap tires which need management. A risings of large quantities of used rubber products, especially used tires has been increasing every year in Poland, in 2006 it was 160 thousand. The waste management and recycling of used tires become a major environmental problem. It is worth noticing that tires which...

  • GPR simulations for diagnostics of a reinforced concrete beam

    Publication

    - Year 2016

    The most popular technique for modelling of an electromagnetic field, the finite difference time domain (FDTD) method, has recently become a popular technique as an interpretation tool for ground penetrating radar (GPR) measurements. The aim of this study is to detect the size and the position of damage in a reinforced concrete beam using GPR maps. Numerical simulations were carried out using the finite differ-ence time domain...

  • Green Chromatography: State-of-the-art, Opportunities and Future Perspectives

    It is well known that chromatographic procedures could have a significant impact on the environment if laboratory practice is not in line with the principles of green analytical chemistry (GAC). However, chromatographic techniques have the potential to be greener in all steps of the analysis. The approaches used to make chromatographic separations greener differ depending on the type of chromatographic method. This chapter considers...

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  • Knowledge risks inherent in business sustainability

    Publication

    - JOURNAL OF CLEANER PRODUCTION - Year 2020

    Since the connection between business sustainability and knowledge risks has not been established in the literature so far, this paper provides a conceptual framework to demonstrate the possible impact of various knowledge risks on business sustainability and offers potential ways to manage and overcome these risks. The aim of this conceptual paper is to address two main questions: What are the potential effects of knowledge risks...

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  • Some variants of perfect graphs related to the matching number, the vertex cover and the weakly connected domination number

    Publication

    Given two types of graph theoretical parameters ρ and σ, we say that a graph G is (σ, ρ)- perfect if σ(H) = ρ(H) for every non-trivial connected induced subgraph H of G. In this work we characterize (γw, τ )-perfect graphs, (γw, α′)-perfect graphs, and (α′, τ )-perfect graphs, where γw(G), τ (G) and α′(G) denote the weakly connected domination number, the vertex cover number and the matching number of G, respectively. Moreover,...

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  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017327761]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017329541]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [7040247104932191]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017321751]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017329151]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017328431]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017326821]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Synovial sarcoma, NOS - Male, 71 - Tissue image [6190730017328631]

    Open Research Data

    This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

  • Transcriptomic Effects of Estrogen Starvation and Induction in the MCF7 Cells. The Meta-analysis of Microarray Results

    Publication

    - CURRENT PHARMACEUTICAL BIOTECHNOLOGY - Year 2015

    Estrogen is one of the most important signaling molecules which targets a number of genes. Estrogen levels regulate cell proliferation and a plethora of metabolic processes, which may interfere with a range of medical conditions and drug metabolism. The MCF7 breast cancer cell line, expressing the estrogen receptor α, is a well-studied model of cellular answer to estrogen. The aim of this study was to characterize transcriptomic...

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  • Production of trehalose in a single step enzymatic reaction

    The aim of this study was isolation and cloning of trehalose synthase gene derived from extremophilic microorganisms Deinoccoci to the expressive E. coli vectors and its biosythesis in different hosts.

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  • Smart metering - social risk perception and risk governance (10h, 2 ECTS credits)

    e-Learning Courses
    • M. Galik
    • A. Klej

    The goal of the course is to broaden the understanding of technology-related risks and to present the concepts of social risk perception and risk governance in the context of smart metering technology. In current phase of technological development – known as the fourth industrial revolution – rapid and profound changes are setting up new and particularly destabilizing risks. In more and more complex technological systems that constitute...

  • The New LM-PCR/Shifter Method for the Genotyping of Microorganism

    Techniques relies on the ligation of appropriates adapters (LM-PCR) as AFLP, PCR MP and ADSRRS are successfully used for epidemiological studies for prokaryotic and eukaryotic microorganisms. In this study we propose a new method, called the LM-PCR/Shifter, based on the use of a Class IIS restriction enzyme giving restriction fragments with different 4 base 5' overhangs (Shifter) and the ligation of appropriate oligonucleotide...

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  • From polymer waste to potential main industrial products: Actual state of recycling and recovering

    lastics have become widely used materials in everyday life due to their special properties such as durability, easy processing, light-weight and low-cost of production. However, because of their stable and non-biodegradable nature, postconsumer plastics become an issue to the environment. The growing amounts of waste are generated, as plastic products are commonly used only once before disposal. The alternatives of practical techniques...

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  • Global Design Optimization of Microwave Circuits Using Response Feature Inverse Surrogates

    Publication

    - Year 2022

    Modern microwave design has become heavily reliant on full-wave electromagnetic (EM) simulation tools, which are necessary for accurate evaluation of microwave components. Consequently, it is also indispensable for their development, especially the adjustment of geometry parameters, oriented towards performance improvement. However, EM-driven optimization procedures incur considerable computational expenses, which may become impractical...

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  • Customer Assessment of Brand Valuation and Social Media

    Publication

    - Year 2016

    The research problem engaged in this article is to determine whether contemporary consumers are able to assess brand equity in the overabundance of brands and products with similar features and qualities. The author argues that in the existing circumstances when differences between brands become insignificant the consumer is not capable of assessing their equity adequately. In order to verify the thesis the author has accepted...

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  • Introducing concurrent engineering to space and satellite technology undergraduate course

    Publication

    - Year 2018

    In recent decade concurrent engineering has become a de facto leading methodology of work in space, aeronautics and sometimes even automotive industry. It has been used in designing ESA space missions for 20 years now, with rst Concurrent Design Facility (CDF) built in ESTEC in 1998. Still, it has not become a universal standard in engineering, and universities are specically reluctant to adopt it into their curricula. As a result,...

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  • Molecular Dynamics to Predict Cryo-EM: Capturing Transitions and Short-Lived Conformational States of Biomolecules

    Publication

    Single-particle cryogenic electron microscopy (cryo-EM) has revolutionized the field of the structural biology, providing an access to the atomic resolution structures of large biomolecular complexes in their near-native environment. Today’s cryo-EM maps can frequently reach the atomic-level resolution, while often containing a range of resolutions, with conformationally variable regions obtained at 6 Å or worse. Low resolution...

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  • Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound

    Publication
    • K. Łuczkowska
    • K. E. Sokołowska
    • O. Taryma-Leśniak
    • K. Pastuszak
    • A. Supernat
    • J. Bybjerg-Grauholm
    • L. L. Hansen
    • E. Paczkowska
    • T. K. Wojdacz
    • B. Machaliński

    - Scientific Reports - Year 2021

    The anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have been shown in neuroblastoma. As BTZ treatment is usually administered in cycles, the development of resistance and side effects in patients undergoing therapy with BTZ remains a major challenge for the clinical usage of this compound. Common resistance development also means...

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  • Architektura latarni morskich wczoraj i dziś

    Publication

    - Logistyka - Year 2015

    Latarnie morskie jako znaki nawigacyjne są niezwykle interesującymi obiektami architektonicznymi. Smukłe formy wynikające z ich funkcji oraz specyficzna lokalizacja sprawiają, że są one charakterystycznymi punktami w krajobrazie nadmorskim. Identyfikują go wizualnie i stają się magnesem przyciągającym turystów. Latarnie morskie, jak wszystkie obiekty korzystające z rozwoju budownictwa i techniki zmieniały swoją formę, nie zmieniając...

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  • Wspólnota mieszkańców - passé?

    Publication

    Local community - a term associated with the notion of neighbourhood and the quality of living environment - do not seem attractive to architects in Poland nowadays. Following years of collectivism enforced by top-down political decisions, one can currently observe bottom-up movements - attempts of building local communities. This paper presents research of chosen case studies (both Polish and foreign) illustrating the above approach....

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  • Services Marketing Influence On Marketing Theory Evolution,

    Publication

    - Handel Wewnętrzny - Year 2017

    The discovery of differences between tangible goods and services in the 1970s was one of the most landmark moments in the history of marketing with an emphasis being shifted to the need for using different/diversified marketing activities while dealing with various industries and types of products. The objective of this article is to briefly characterise the evolution of the marketing thought and to present the crucial influence...

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  • Sensors in River Information Services of the Odra River in Poland: Current State and Planned Extension

    Publication

    - Year 2017

    According to adopted in 2016 by the polish Council of Ministers assumptions for the plans for the progress of inland waterways in Poland for the years 2016-2020, with the perspective of 2030, assume that by 2030 Odra along its entire length and the Vistula from Warsaw to Gdansk, they will have become international shipping routes, which will be implemented system of River Information Services (RIS). Aspects of RIS sensor application...

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  • Basics on Commodities Risk Management for Grains Trading

    Publication

    Celem artykułu jest określenie rodzajów grup ryzyka występujących na rynku zbóż oraz przedstawienie możliwości ograniczania wystąpienia zjawisk niepożądanych. Pojawia się kwestia: w jakim stopniu podmioty rynku zbóż, a w szczególności producenci, powinni sami neutralizować występujące ryzyko, a kiedy powinni oczekiwać wsparcia ze strony instytucji państwowych. Coraz powszechniej zastosowanie znajdują instrumenty finansowe w postaci...

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  • Gendered entrepreneurship and its impact on firm innovativeness - a literature review.

    Entrepreneurs gain a lot of attention in recent decades. Even if a precise definition of entrepreneur and entrepreneurship remains problematic, it is clear that there is a strong link between entrepreneurship and innovativeness, as well as between entrepreneur and innovation. In the current era of globalisation, the importance of innovations is as great as never before. And so is the importance of innovativeness determinants. Investigating...

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