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Reliability of Structures
e-Learning CoursesReliability of Structures, 2nd grade studies, Civil Engineering
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Effects of preheating on laser beam–welded NSSC 2120 lean duplex steel
PublicationDuplex stainless steels show sustainable alternative for the conventional austenitic grades, with higher strength, higher resistance against stress corrosion cracking, and lower purchase cost. Thus, duplex stainless steel gains more attention in construction, oil and gas, and chemical industries. Among duplex stainless steels, low nickel and low molybdenum alloyed lean duplex stainless steel are a cost-efective substitution of...
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Green Inorganic Technologies - 2022
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Nuclear Energy [2021/22]
e-Learning CoursesThe course is dedicated to students of the Green Technologies and Monitoring - Faculty of Chemistry
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Geographic Information Systems 2021/2022
e-Learning CoursesWydział Chemii, studia magisterskie, kierunek Green Technologies and Monitoring
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Geographic Information Systems
e-Learning CoursesWydział Chemii, studia magisterskie, kierunek Green Technologies and Monitoring
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In silico study on the effects of carbonyl groups on chemical equilibrium of reactions with a polar product occurring under confinement in pores of activated carbons
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Emotional distress, burnout and sense of safety during the COVID-19 pandemic in teachers after the reopening of schools
PublicationThe COVID-19 pandemic is having a significant impact on people's psychological well-being and mental health. This study aimed to identify factors linked to emotional distress, burnout and sense of safety in teachers related to the reopening of Polish schools after lockdown, remote work, and the holiday period between March and August 2020. A total of 1,286 teachers from different educational institutions participated in the...
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Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
PublicationEnterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred...
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Pesticide analysis of bee and bee product samples
PublicationBee products possess therapeutic properties and are the source of many essential trace elements,which is why they are regarded as valuable food products. Honey bees may bring to thehive numerous contaminants deposited on the plants they visit, including pesticide withoutxenobiotics. The large-scale application of pesticides in agriculture and horticulture can lead tomass mortality among bees, and the chemicals find their way into...
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Pesticide Analysis of Bee and Bee Product Samples
PublicationBee products possess therapeutic properties and are the source of many essential trace elements,which is why they are regarded as valuable food products. Honey bees may bring to thehive numerous contaminants deposited on the plants they visit, including pesticide withoutxenobiotics. The large-scale application of pesticides in agriculture and horticulture can lead tomass mortality among bees, and the chemicals find their way into...
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Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations
PublicationIncreasing evidence indicates a role of hyperpolarization activated cation (HCN) channels in controlling the resting membrane potential, pacemaker activity, memory formation, sleep, and arousal. Their disfunction may be associated with the development of epilepsy and age-related memory decline. Neuronal hyperexcitability involved in epileptogenesis and EEG desynchronization occur in the course of dementia in human Alzheimer’s Disease...
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Targeting DNA Topoisomerase II in Antifungal Chemotherapy.
PublicationTopoisomerase inhibitors have been in use clinically for the treatment of several diseases for decades. Although those enzymes are significant molecular targets in antibacterial and anticancer chemotherapy very little is known about the possibilities to target fungal topoisomerase II (topo II). Raising concern for the fungal infections, lack of effective drugs and a phenomenon of multidrug resistance underlie a strong need to expand...
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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublicationColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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Automatics and control of technical processes 2023
e-Learning CoursesAutomatics and control of technical processes for Green Technologies 2023
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Green Small Craft Green Cruising for High-speed Small Craft in The Baltic Sea
ProjectsProject realized in Faculty of Ocean Engineering and Ship Technology according to #S057 agreement from 2020-06-23
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Dual inhibition of PI3K/Akt signaling and the DNA damage checkpoint in p53-deficient cells with strong survival signaling: implications for cancer therapy
PublicationOporność komórek nowotworowych na leki uszkadzjące DNA związana jest ściśle ze zdolnością do utrzymywania blok z fazie G2 cyklu komórkowego. Blok ten regulowany jest przez mechanizmy punktu kontrolnego G2/M oraz szlaki przeżycia komórkowego. W pracy badaliśmy rolę szlaku kinazy PI3K/Akt w funkcjonowaniu punktu kontrolnego cyklu komórkowego i wpływ na przeżycie komórek traktowanych lekiem przeciwnowotworowym - cisplatyną. Nasze...
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Cross-talk between DNA damage and cell survival checkpoints during G2 and mitosis: pharmacological implications
PublicationW pracy wyjaśnialiśmy rolę surwiwiny w ochronie komórek w czasie przejścia między G2 i mitozą, traktowanych związkiem uszkadzającym DNA. Jako model komórkowy wybraliśmy komórki ludzkiej białaczki MOLT-4, które wykazują zwiększoną ekspresję białka surwiwiny i niefunkcjonalnym p53. Ekspozycja tych komórek na melfalan, klasyczny związek uszkadzający DNA, prowadzi do uruchomienia punktu kontrolnego w G2 i zablokowania progresji cyklu...
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Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitorstoward human carcinoma cells with different p53 status
PublicationRola bloku G2 w efekcie cytotoksycznym inhibitorów DNA topoizomeraz w stosunku do ludzkich komórek rakowych różniących się funkcjonalnością białka p53.
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From creative writing, virtual environments to nature-based solutions: linking research and education to facilitate transition from sustainable to regenerative cities
PublicationChallenges related to the climate crisis and its consequences, such as rising sea levels, urban heat islands or floods, engender pressure on architectural education. Sustainable design often inclines to regenerative one - an emerging trend focused on the restorative power of architecture. The question appears upon the tools and methods that would facilitate both students and academics to address new challenges. This article offers...
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Resilience and Security in Software Defined Networking
PublicationThis paper gives an overview of the most important issues on resilience and security in Software Defined Networking
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Fabrication and Crystal Structure of Sol-Gel Deposited BST Thin Films with Compositional Gradient
PublicationIn the present research technology of compositionally graded barium strontium titanate Ba1-xSrxTiO3 thin films deposited on stainless steel substrates by sol-gel spin coating followed with thermal annealing at T = 650°C is reported. Results of thermal behavior of the sol-gel derived powders with compositions used for fabrication of graded structure (i.e. with Sr mole fraction x = 0.5, 0.4 and 0.3) are described. X-ray diffraction...
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Thermo-Chemical Decomposition Study of Polyurethane Elastomer Through Glycerolysis Route with Using Crude and Refined Glycerine as a Transesterification Agent
PublicationDue to the increasing amount of polyurethane waste, chemical recycling of these materials is a topic of growing interest for many researchers. The primary pur- pose of polyurethane feedstock recycling is to recover the starting polyol. In this study glycerolysis using glycerine from two sources and two purity grades is proposed as a method of chemical recycling. The main effort of this paper focuses on the employment of commercial...
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The Finite Pore Volume GAB Adsorption Isotherm Model as a Simple Tool to Estimate a Diameter of Cylindrical Nanopores
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Modyfikacja połączenia dźwigara ze słupem w konstrukcji stalowej Terminalu T2 Portu Lotniczego w Gdańsku
PublicationW2015 r. ukończono rozbudowę Terminalu T2 Portu Lotniczego im. Lecha Wałęsy wGdańsku. Politechnika Gdańska pełniła nadzór naukowy nad rozbudową obiektu. Wykonano wiele analiz, których celem była weryfikacja pracy konstrukcji w fazach montażu oraz w stanie docelowym. Wnioski z przeprowadzonych badań doprowadziły do modyfikacji oparcia dźwigarów dachowych na stalowych słupach nośnych, z uwagi na stwierdzone lokalne przekroczenia...
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New methods for assessment and stimulation of non-communicative patients employing advanced multimodal HCI . Nowe metody oceny i stymulacji pacjentów niekomunikatywnych z wykorzystaniem zaawansowanych interfejsów multimodalnych człowiek-komputer
PublicationIn most cases of patients with locomotor system damage it is possible to find a solution to the medical problems originating from the injury. However, it is much more difficult to prevent cognitive and emotional impairments. Therefore, we believe that the technological support of therapists working with such patients on an everyday basis may be essential. We have acquired experience in designing and providing diagnostic and therapeutic...
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SYNTHESIZING MEDICAL TERMS – QUALITY AND NATURALNESS OF THE DEEP TEXT-TO-SPEECH ALGORITHM
PublicationThe main purpose of this study is to develop a deep text-to-speech (TTS) algorithm designated for an embedded system device. First, a critical literature review of state-of-the-art speech synthesis deep models is provided. The algorithm implementation covers both hardware and algorithmic solutions. The algorithm is designed for use with the Raspberry Pi 4 board. 80 synthesized sentences were prepared based on medical and everyday...
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Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor
PublicationGranulocyte macrophage colony stimulating factor (GMCSF) is an immunomodulatory cytokine that is harnessed as a therapeutic. GMCSF is known to interact with other clinically important molecules, such as heparin, suggesting that endogenous and administered GMCSF has the potential to modulate orthogonal treatment outcomes. Thus, molecular level characterization of GMCSF and its interactions with biologically active compounds is critical...
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Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis
PublicationPsoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It occurs more often in patients with a more severe course of the disease. Obesity is specially an independent risk factor and it is associated with a worse treatment outcome because of the high inflammatory activity of visceral fatty tissue and...
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Cytocompatibility of stabilized black phosphorus nanosheets tailored by directly conjugated polymeric micelles for human breast cancer therapy
PublicationThe novel procedure of few-layer black phosphorus (FLBP) stabilization and functionalisation was here proposed. The cationic polymer PLL and non-ionic PEG have been involved into encapsulation of FLBP to allow sufficient time for further nanofabrication process and overcome environmental degradation. Two different spacer chemistry was designed to bind polymers to tumor-homing peptides. The efficiency of functionalisation was examined...
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Use of Escherichia coli Nissle 1917 producing recombinant colicins for treatment of IBD patients
PublicationPatients with Crohn’s Disease and ulcerative colitis infected with Adherent-Invasive Escherichia coli strains constitute the largest group among Inflammatory Bowel Disease subjects, when taking into account all known etiological agents of the disease. A possible link between these pathogenic bacteria and inflammation process has gained the confidence in recently published papers. Observed enteric neuroglial cells apoptosis and...
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Supramolecular deep eutectic solvents and their applications
PublicationIn recent years, the growing awareness of the harmfulness of chemicals to the environment has resulted in the development of green and sustainable technologies. The compromise between economy and environmental requirements is based on the development of new efficient and green solutions. Supramolecular deep eutectic solvents (SUPRADESs), a new deep eutectic solvent (DES) subclass characterized by inclusion properties, are a fresh...
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The use of HPLC-Q-TOF-MS for comprehensive screening of drugs and psychoactive substances in hair samples and several “legal highs” products
PublicationNon-targeted screening of drugs present in herbal products, known as “legal high” drugs and in hair as a biological matrix commonly used in toxicological investigations was accomplished with the use of high pressure liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS). In total, 25 and 14 therapeutical drugs and psychoactive substances/metabolites were detected in investigated hair samples...
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Analytical eco-scale for assessing the greenness of analytical procedures
PublicationWe propose the analytical eco-scale as a novel comprehensive approach to evaluating the greenness of analytical methodology. It is based on assigning penalty points to parameters of an analytical process that are not in agreement with the ideal green analysis. This approach compares different parameters and different steps of the analytical process. Traditional green chemistry metrics 9e.g. Atom Economy, E-factor and Reaction Mass...
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Modyfikacja cementu kostnego w celu uzyskania długotrwałej ochrony antybakteryjnej
PublicationNiniejsza rozprawa doktorska stanowi przewodnik po jednotematycznym cyklu publikacji, dotyczącym modyfikacji akrylowego cementu kostnego celem uzyskania długotrwałej i efektywnej ochrony antybakteryjnej. W ramach niego przeprowadzono badania eksperymentalne polegające na opracowaniu technologii wytwarzania modyfikowanego cementu kostnego oraz procedury medycznej jego stosowania. Cement kostny był modyfikowany przez zastosowanie...
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The influence of selected strain-based failure criteria on ship structure damage resulting from a collision with an offshore wind turbine monopile
PublicationOffshore wind farms are developing well all over the world, providing green energy from renewable sources. The evaluation of possible consequences of a collision involves Finite Element computer simulations. The goal of this paper was to analyse the influence of selected strain-based failure criteria on ship damage resulting from a collision with an offshore wind turbine monopile. The case of a collision between an offshore supply...
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Green Organic Technologies 2022/23
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Green Inorganic Technologies - 2022/23
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Green Inorganic Technologies 23/24
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Monika Arczyńska dr inż. arch.
PeopleArchitect and researcher with over 10 years of international experience in cultural projects. She has been working on the designs of Grand Egyptian Museum in Cairo, Palestinian Museum in East Bank, Giant’s Causeway Visitor Centre and National Centre for Contemporary Art in Moscow (with Heneghan Peng Architects). As a founder of A2P2 architecture & planning she runs architecture department of the company. In 2018 together with...
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Cezary Wąs Profesor
PeopleDr. habil. Cezary Was Assistant Professor at the Institute of Art History, University of Wrocław. Curator of the Museum of Architecture (1986-2021). Author of the books: Antynomie współczesnej architektury sakralnej (Antinomies of the Contemporary Sacred Architecture, 2008), Architektura a dekonstrukcja. Przypadek Petera Eisenmana i Bernarda Tschumiego (Architecture and Deconstruction. The Case of Peter Eisenman and Bernard Tschumi,...
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Antitumor 1-nitroacridine derivative C-1748 induces significant apoptosis in pancreatic cancer cells.
PublicationPancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer in the industrial countries. The poor prognosis of pancreatic cancer results from its tendency for late presentation, aggressive invasion, early metastasis, and resistance to chemotherapy. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine...
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Simple smartphone-based methods for the determination of bioactive compounds in wine
PublicationA set of simple smartphone-based methods of bioactive compounds determination were developed for wine analysis. Procedures for smartphone-based determination of the total content of phenolic compounds, flavonoids, anthocyanins and biogenic amines, as well as measurement of antioxidant activity were developed and fully validated. The experimental setup is based on smartphone and 3D-printed device, though it is very simple and can...
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Assessment of Connectivity-based Resilience to Attacks Against Multiple Nodes in SDNs
PublicationIn Software Defined Networks (SDNs), the control plane of a network is decoupled from its data plane. For scalability and robustness, the logically centralized control plane is implemented by physically placing different controllers throughout the network. The determination of the number and placement of controllers is known as the Controller Placement Problem (CPP). In the regular (i.e., failure-free) state, the control plane...
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The process generation of WWTP models for optimization of activated sludge systems
PublicationThe objective of water and wastewater utilities, which are responsible for optimization of wastewater treatment plant operation, is threefold: environmental protection, saving money, and mitigation of pollutant emissions, both to water and air. The performed study aimed to assess the process generation of WWTP models that improve activated sludge systems operation, by means of new developed Mantis2 model. This model accounts for...
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Ireneusz Kreja dr hab. inż.
PeopleGraduated from the mathematical class at the Nicolaus Copernicus High School in Gdańsk (1974). Master of Sciences in Civil Engineering after studies at Gdansk University of Technology (GUT), Poland (1974-1979). Since 1979 became an employee of the GUT. In 1989 earned a Ph.D. degree in Civil Engineering (with grade "Summa cum Laude") from the GUT. In 2008 obtained a D. Sc. (Habilitation) degree in Civil Engineering (with grade...
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Topical delivery of pharmaceutical and cosmetic macromolecules using microemulsion systems
PublicationMicroemulsions are transparent, thermodynamically stable colloidal systems. Over the recent years, they have been increasingly investigated due to their potential as skin delivery vehicles for a wide range of drug molecules. The nanoscale particle size and the specificity of microemulsion components are the main features determining the skin permeation process. However, in order to effectively cross the skin barrier, the active...
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‘Acridines’ as New Horizons in Antifungal Treatment
PublicationFrequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide. The repertoire of antifungal chemotherapeutic agents is very limited. Although new antifungal drugs such as lanosterol 14α-demethylase and β-glucan synthase inhibitors have been introduced into clinical...
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Receptor for advanced glycation end‐products: Biological significance and imaging applications
PublicationThe receptor for advanced glycation end-products (RAGE or AGER) is a transmembrane, immunoglobulin-like receptor that, due to its multiple isoform structures, binds to a diverse range of endo- and exogenous ligands. RAGE activation caused by the ligand binding initiates a cascade of complex pathways associated with producing free radicals, such as reactive nitric oxide and oxygen species, cell proliferation, and immunoinflammatory...
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Biopolymer based nanomaterials in drug delivery systems: A review
PublicationDrug delivery systems (DDS) are used to achieve a higher therapeutic effects of a pharmaceutical drug or natural compound in a specific diseased site with minimal toxicological effect and these systems consists of liposomes, microspheres, gels, prodrugs and many. Nanotechnology is a rapidly developing multi-disciplinary science that ensures the fabrication of the polymers to nanometer scale for various medical applications. Uses...