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Sources and composition of chemical pollution in Maritime Antarctica (King George Island), part 1: Sediment and water analysis for PAH sources evaluation in the vicinity of Arctowski station
PublikacjaThe paper presents a study regarding the identification of polycyclic aromatic hydrocarbons (PAHs) in fresh waters and surface sediments on the western shore of Admiralty Bay over four sampling seasons from 2017 to 2018. The results were compared to literature data from 2016 to provide a more comprehensive image of the environmental fate of PAHs over the years. The highest value of Σ PAHs was 82.9 ng/L and 445 ng/g dw in water...
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Transcriptomic Effects of Estrogen Starvation and Induction in the MCF7 Cells. The Meta-analysis of Microarray Results
PublikacjaEstrogen is one of the most important signaling molecules which targets a number of genes. Estrogen levels regulate cell proliferation and a plethora of metabolic processes, which may interfere with a range of medical conditions and drug metabolism. The MCF7 breast cancer cell line, expressing the estrogen receptor α, is a well-studied model of cellular answer to estrogen. The aim of this study was to characterize transcriptomic...
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Functional safety and reliability analysis methodoloogy for hazardous industrial plants
PublikacjaThis monograph is devoted to current problems and methods of the functional safety and reliability analyses of the programmable control and protection systems for industrial hazardous plants. The results of these analyses are useful in the process of safety management in life cycle, for effective reducing relevant risks at the design stage, and then controlling these risks during the operation of given installation. The methodology...
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Tools for road infrastructure safety management – Polish experiences
PublikacjaThe objective of road safety infrastructure management is to ensure that when roads are planned, designed, built and used road risks can be systematically identified, assessed, removed and mitigated. There are a number of approaches to road safety management. European Union Directive 2008/96/EC requires EU member states to use four basic tools of road safety infrastructure management. An overview of the methods in these countries...
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CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
PublikacjaWe examine whether CYP3A4 overexpression influences the rate and pattern of antitumor imidazoacridinone C-1311 metabolism, in relation to the impact of this overexpression on cell cycle progression and final cellular response of CHO cells following C-1311 treatment. Methods: Three CHO cell lines: CHO-WT, wild type, CHO-HR, overexpressing cytochrome P450 reductase (CPR) and CHO-HR-3A4, coexpressing CPR and CYP3A4 were applied....
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Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.
PublikacjaThe acridinone derivates C-1305 and C-1311 are promising antitumor agents with high activity against several experimental cellular and tumor models and which are under evaluation in pre-clinical and early phase clinical trials. Recent evidence from our laboratories has indicated that both compounds were conjugated by several UGT isoforms with the most active being extrahepatic UGT1A10. The present studies were designed to test...
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Investigating the Effects of Geometrical Parameters of Re-Entrant Cells of Aluminum 7075-T651 Auxetic Structures on Fatigue Life
PublikacjaIn this study, the effects of two geometrical parameters of the re-entrant auxetic cells, namely, internal cell angle (θ) and H/L ratio in which H is the cell height, and L is the cell length, have been studied on the variations of Poisson’s ratio and fatigue life of Aluminum 7075-T6 auxetic structures. Five different values of both the H/L ratio and angle θ were selected. Numerical simulations and fatigue life predictions have...
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DIAGNOSTIC INFORMATION ANALYSIS OF QUICKLY CHANGING TEMPERATURE OF EXHAUST GAS FROM MARINE DIESEL ENGINE PART I SINGLE FACTOR ANALYSIS
PublikacjaIn this paper, attention was paid to the problem of low controllability of marine medium- and high-speed engines during operation, which significantly limits the parametric diagnosis. The measurement of quickly changing temperature of engine exhaust gas was proposed, the courses of which can be a source of diagnostic information. The F statistic of the Fisher-Snedecor distribution was chosen as a statistical tool. Laboratory tests...
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Migration of container terminals as their natural process of evolution: Case study of Gdańsk and Gdynia ports
PublikacjaThe paper proposes a theoretical model of container terminals and container port development, based on the life cycle theory, threshold theory and catastrophe theory, and in references to Kuznets' swings (interpreted as waves of infrastructural investments), and Kondratiev long economic waves. The aim of this model is to explain the development process of a container terminal and a port within one technological generation, as...
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Sources of contamination in sediments of retention tanks and the influence of precipitation type on the size of pollution load
PublikacjaDensification of cities and urban population contributes to increased runoff and suspended solids and alteration of the urban water cycle. Nowadays, Blue-Green Infrastructure is promoted to increase a city’s resilience to floods; however, stormwater drainage systems, supported with retention tanks are still important in protecting urban areas against floods. Sediment accumulation in stormwater infrastructure relates to an issue...
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Effect of Arc Strikes on High Strength Low Alloy Steels Welded by SMAW
PublikacjaWet welding with covered electrodes (Shielded Metal Arc Welding – SMAW) is the most commonly used method of carrying out welding repair works in a water environment. Limited visibility and the inability to move freely under water result in an increased risk of formation of welding imperfections such as lack of fusion, lack of penetration and arc strikes. The work focused on changes in the properties and structure of steel subjected...
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MXene-based materials as adsorbents, photocatalysts, membranes and sensors for detection and removal of emerging and gaseous pollutants: A comprehensive review
Publikacja2D materials have garnered significant attention as potential solutions to various environmental challenges. Graphene, molybdenum disulfide, MXenes, and boron nitride have emerged as the most popular candidates among these materials. This article presents a comprehensive review and discussion on the emerging applications of MXenes in environmental engineering. MXenes have demonstrated immense potential as future materials for adsorption...
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Design and Evaluation of the Compact and Autonomous Energy Subsystem of a Wave Energy Converter
PublikacjaThis paper presents the results of the design process focused on the development of the energy subsystem (ES) of a wave energy converter (WEC). The ES is an important electrical part that significantly affects the energy reliability and energy efficiency of the entire WEC device. The designed ES was intended for compact WECs powering IoT network devices working in the distributed grid. The developed ES is an electronic circuit...
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Expermental investigation on adsorption of methylene blue dye from waste water using corncob cellulose-based hydrogel
PublikacjaHydrogel from corncob cellulose was synthesized in this investigation. The synthesized Hydrogel was characterized by SEM, XRD, and FTIR instruments. As the results indicate the synthesized hydrogel has required and important features, these suggest the suitability of hydrogel for the adsorption of methylene blue dye (MBD). Three important process variables (dosage, contact time, and initial concentration) with three levels were...
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15th Conference on Calorimetry and Thermal Analysis
WydarzeniaRegistration for the workshops with Sponsors, which will take place during the free time on Tuesday, September 10, 2024, from 2:30 PM, will be conducted by signing up on a list at the registration desk. We kindly inform you that posters should be prepared in size B1 (707 x 1000 mm). Templates:pptx, pdf Please submit your presentations...
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BIOSTATYSTYKA
Kursy OnlineCelem przedmiotu biostatystyka jest przedstawienie narzędzi praktycznych z zakresu analizy zmiennych biologicznych i biomedycznych przy wykorzystaniu programów Excel oraz SAS (North Carolina, USA). Program SAS jest najczęściej używanym narzędziem do analiz statystycznych w przemyśle i badaniach naukowych. Student uzyskuje umiejętności niezbędne podczas projektowania i prowadzenia eksperymentów naukowych oraz prowadzenia prac badawczych...
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PG-00060238 Standardy integralności mechanicznej dla inżynierii cyfrowej opartej na danych
Kursy OnlineKurs w zrozumiały sposób wyjaśnia praktyki inżynierskie dotyczące oceny mechanizmów awarii elementów mechanicznych, metody Stress-Life i Strain-Life, techniki liczenia cykli. Wyjaśnione modele oparte na wiedzy analitycznej są odniesione do potrzeb monitorowania silnika, które generuje dane pracy urządzeń u klientów. Dane te są wykorzystywane w rozwiązaniach inżynierii cyfrowej, takich jak digital twin (dla części) lub digital thread...
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Preconditioners with Low Memory Requirements for Higher-Order Finite-Element Method Applied to Solving Maxwell’s Equations on Multicore CPUs and GPUs
PublikacjaThis paper discusses two fast implementations of the conjugate gradient iterative method using a hierarchical multilevel preconditioner to solve the complex-valued, sparse systems obtained using the higher order finite-element method applied to the solution of the time-harmonic Maxwell equations. In the first implementation, denoted PCG-V, a classical V-cycle is applied and the system of equations on the lowest level is solved...
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The influence of the Cu2O deposition method on the structure, morphology and photoresponse of the ordered TiO2NTs/Cu2O heterojunction
PublikacjaThe increased interest in highly ordered titania structures exhibiting tubular shape that could be directly formed onto the stable substrate is related with the intensive research on their modification enabling absorption of light within the wide solar spectrum and its further conversion into electric or chemical energy. Among others, formation of uniform 3D heterojunctions based on the TiO2 nanotubes attracts attention since porous...
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LED Light Sources and Their Complex Set-Up for Visually and Biologically Effective Illumination for Ornamental Indoor Plants
PublikacjaOrnamental plants are often used in indoor environments as part of biophilic design to improve the health and wellbeing of occupants, and to support sustainable, green architecture. Unfortunately, many plants do not thrive and need to be continuously replaced, which is economically unsustainable. The wavelengths and spectrum ratio of commonly used light sources such as light emitting diode (LED), and the lack of an appropriate...
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
PublikacjaAn important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...
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Storm petrels as indicators of pelagic seabird exposure to chemical elements in the Antarctic marine ecosystem
PublikacjaData on trace element bioavailability in the south-polar marine ecosystem is still scarce, compared to that relating to temperate zones. Seabirds can be used as indicators of ecosystem health and sentinels of environmental pollution, constituting a link between marine and terrestrial environments. Here, we analysed the concentration of 17 elements (with special emphasis on mercury, Hg) in feathers of adults and chicks of two pelagic...
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Challenges of overcoming ageism towards elderly people in healthcare context
PublikacjaRESEARCH OBJECTIVE: The purpose of the paper is to analyse the impact ageism may have on providing healthcare to elderly people. THE RESEARCH PROBLEM AND METHODS: The article investigates the consequences of ageism in medical settings, where the elderly are particularly vulnerable to discrimination, distinguishing ageism from appropriate practice variation as well as giving suggestions to improve the situation. The paper analyses...
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Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints
PublikacjaOur previous studies have shown that murine fibroblast cells, in which PARP-1 gene was inactivated by gene disruption, are extremely sensitive to triazoloacridone compound C-1305, an inhibitor of DNA topoisomerase II with unusual properties. Here, we show that pharmacological inhibition of PARP-1 activity by its inhibitor compound NU1025, sensitizes human cervical carcinoma HeLa cells to compound C-1305 compared to treatment with...
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Porous carbon derived from rice husks as sustainable bioresources: insights into the role of micro-/mesoporous hierarchy in hosting active species for lithium–sulphur batteries
PublikacjaThe exploration of natural resources as sustainable precursors affords a family of green materials. Exploring highly abundant and available biowaste precursors remaining from food processing throughout a scalable and cost-effective material synthesis path is highly important especially for new materials discovery in emerging energy storage technologies such as lithium–sulphur (Li–S) batteries. Herein, we have produced a series...
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The Environmental Benefits of Photovoltaic Systems: The Impact on the Environment in the Production of Photovoltaic Systems: With a Focus on Metal Recovery
PublikacjaGreenhouse gases (GHGs) such as carbon dioxide, nitrous oxide and methane, trap heat and energy, thus preventing solar radiation from escaping back into space. As the quantity of greenhouse gases in the atmosphere increases so does the trapped heat and corresponding global temperature. As a result, storms become more violent, droughts more prevalent, glaciers melt, and sea levels rise, to name but a few effects of a rapidly changing...
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Management of Urban Waters with Nature-Based Solutions in Circular Cities—Exemplified through Seven Urban Circularity Challenges
PublikacjaNature-Based Solutions (NBS) have been proven to effectively mitigate and solve resource depletion and climate-related challenges in urban areas. The COST (Cooperation in Science and Technology) Action CA17133 entitled “Implementing nature-based solutions (NBS) for building a resourceful circular city” has established seven urban circularity challenges (UCC) that can be addressed effectively with NBS. This paper presents the outcomes...
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In situ spectroelectrochemical and theoretical study on the oxidation of a 4H-imidazole-ruthenium dye adsorbed on nanocrystalline TiO2thin film electrodes
PublikacjaTerpyridine 4H-imidazole-ruthenium(ii) complexes are considered promising candidates for use as sensitizers in dye sensitized solar cells (DSSCs) by displaying broad absorption in the visible range, where the dominant absorption features are due to metal-to-ligand charge transfer (MLCT) transitions. The ruthenium(iii) intermediates resulting from photoinduced MLCT transitions are essential intermediates in the photoredox-cycle...
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Multi-Temporal Analysis of Changes of the Southern Part of the Baltic Sea Coast Using Aerial Remote Sensing Data
PublikacjaUnderstanding processes that affect changes in the coastal zone and the ability to predict these processes in the future depends on the period for which detailed monitoring is carried out and on the type of coast. This paper analyzes a southern fragment of the Baltic coast (30 km), where there has been no anthropogenic impact (Slowinski National Park). The study was carried out covering a time interval of 65 years. Historic and...
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Diagnostic Analysis of Exhaust Gas with A Quick-Changing Temperature from a Marine Diesel Engine Part II / Two Factor Analysis
PublikacjaThe article presents a continuation of research carried out to determine the effect of input parameters (changes in engine structure parameters) on selected output parameters (diagnostic measures), based on quickly changing exhaust gas temperature. A method of determining the simultaneous influence of two input factors (the structure parameter and the engine load) on one output factor was presented, as well as an evaluation...
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ENVIRONMENTAL ASSESSMENT OF SOLAR CELL MATERIALS
PublikacjaIn today’s world, fossil fuels, including coal, oil, and gas, are the primary energy sources from which electricity is obtained. As they are exhaustible and their exploitation has a negative impact on the natural environment, they should be, at least partially, replaced by renewable energy sources. One of these sources is solar energy. The use of solar energy releases no CO2, SO2, or NO2 gases, and does not contribute to global...
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c-Myc inhibition and p21 modulation contribute to unsymmetrical bisacridines-induced apoptosis and senescence in pancreatic cancer cells
PublikacjaBackground Pancreatic cancer (PC) is one of the most aggressive cancers and is the seventh leading cause of cancer-related death worldwide. PC is characterized by rapid progression and resistance to conventional treatments. Mutations in KRAS, CDKN2A, TP53, SMAD4/DPC4, and MYC are major genetic alterations associated with poor treatment outcomes in patients with PC. Therefore, optimizing PC therapy is a tremendous challenge. Unsymmetrical...
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PROBLEMY ZWIĄZANE Z ZASTOSOWANIEM NANOTECHNOLOGII W TERMOIZOLACJI BUDYNKÓW
PublikacjaBudownictwo i architektura były zawsze ściśle związane z rozwojem technologicznym a ciągły postęp w badaniach nad inżynierią materiałową pozwalał na uzyskiwanie bardziej wydajnych i wytrzymałych materiałów. Dotyczy to nie tylko elementów konstrukcyjnych budynku ale także technologii związanych z jego wykończeniem. Obecnie coraz większą rolę w budownictwie i architekturze odgrywa pojęcie nanotechnologii. Dziedzina nauki, zdawałoby...
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Schronienie – poszukiwanie formuły dla domu wpisanego w relacje środowiskowe
PublikacjaKonieczność schronienia i potrzeba zamieszkiwania wymagają przestrzeni, które współcześnie zazwyczaj zabezpieczają obiekty architektoniczne. Jednak często zauważamy niedobory wartości w przestrzeni zamieszkiwania. Pomysłem zaradczym w tej sytuacji jest powrót do punktu wyjścia. Do zapewnienia schronienia. Jeśli będzie ono wpisane w relacje środowiskowe i ukształtowane w zgodzie z potrzebą zachowania ciągłości kulturowej, ma szansę...
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Architectural project I 2024/25
Kursy OnlineOur course aims to teach you the basics how to design architecture. The process of architectural design is not only about function and construction. It is about creating an original form with individual features and beauty that will become a meaningful part of our environment. Our course in architectural design is based on the connection with ART. We follow the tradition of the famous Bauhaus school, where architects and artists...
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Aluminium in glacial meltwater demonstrates an association with nutrient export (Werenskiöldbreen, Svalbard)
PublikacjaThe aluminium (Al) cycle in glacierised basins has not received a great deal of attention in studies of biogeochemical cycles. As Almay be toxic for biota, it is important to investigate the processes leading to its release into the environment. It has not yet been ascertained whether filterable Al (passing through a pore size of 0.45 m) is incorporated into biogeochemical cycles in glacierised basins. Our study aims to determine...
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Modelling of Different Aeration Modes Influencing Processes in SBR Bioreactor
PublikacjaCurrently, computer modelling together with the simulation tools tailored for that purpose constitute a very important element in planning technological changes within wastewater treatment plant. From the point of view of the WWTP operator every modification should be introduced in order to improve the quality of treated sewage with the lowest financial outlays. These requirements can be met by using computer programmes to effectuate...
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Toward the next generation of air quality monitoring: Mercury
PublikacjaMercury is a global pollutant that is ubiquitous in the environment. Enrichment of mercury in the biosphere as the result of human activities and subsequent production of methylmercury (MeHg) has resulted in elevated concentrations in fish, wildlife and marine mammals globally. Elemental mercury (Hg0) is the most common form of mercury in the atmosphere, and the form that is most readily transported long distances from its emission...
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Rotation Triggers Nucleotide-Independent Conformational Transition of the Empty β Subunit of F1-ATPase
PublikacjaF1-ATPase (F1) is the catalytic portion of ATP synthase, a rotary motor protein that couples proton gradients to ATP synthesis. Driven by a proton flux, the F1 asymmetric γ subunit undergoes a stepwise rotation inside the α3β3 headpiece and causes the β subunits’ binding sites to cycle between states of different affinity for nucleotides. These concerted transitions drive the synthesis of ATP from ADP and phosphate. Here, we study...
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Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublikacjaPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
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Fire Protection and Materials Flammability Control by Artificial Intelligence
PublikacjaFire safety has become a major challenge of materials developers because of the massive production of organic materials, often combustibles, and their use for different purposes. In this sense, fire safety is critically considered in the development of engineering materials [1, 2]. The multiplicity of parameters contributing to the development of formulation of flame-retardant materials from one side and the sustainability concerns...
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Structure-Property Relationship and Multiple Processing Studies of Novel Bio-Based Thermoplastic Polyurethane Elastomers
PublikacjaCurrently, the growing demand for polymeric materials has led to an increased need to develop effective recycling methods. This study focuses on the multiple processing of bio-based thermoplastic polyurethane elastomers (bio-TPUs) as a sustainable approach for polymeric waste management through mechanical recycling. The main objective is to investigate the influence of two reprocessing cycles on selected properties of bio-TPUs....
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Analysis of cyclone separator solutions depending on SEC outlet conditions in nCO2PP
PublikacjaUtilization of spray ejector condenser in order to carry out direct-contact condensation of vapour with inert gas (CO2) on a spray of subcooled liquid integrated with separator (to make pure CO2) has been proposed for the task of condensation and CO2 separation in the negative CO2 emission gas power plant. Condensation and separation has a significant impact on the thermodynamic efficiency of the entire negative CO2 emission gas...
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A novel approach in wood waste utilization for manufacturing of catalyst-free polyurethane-wood composites (PU-WC)
PublikacjaIn recent decades, due to the increase in environmental awareness and noticeable environmental degradation, the area of wood waste management has attracted increasing attention. The purpose of this study is to develop a new type of highly filled polyurethane wood-composite (PU-WC) by the utilization of large amount of wood wastes without addition of a catalyst. Although wood-plastic composites (WPCs) are widely known, there is...
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Marine and Cosmic Inspirations for AI Algorithms
PublikacjaArtificial Intelligence (AI) is a scientific area that currently sees an enormous growth. Various new algorithms and methods are developed and many of them meets practical, successful applications. Authors of new algorithms draw different inspirations. Probably the most common one is the nature. For example, Artificial Neural Networks were inspired by the structure of human brain and nervous system while the classic Genetic Algorithm...
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Thermodynamic, ecological, and economic analysis of negative CO2 emission power plant using gasified sewage sludge
PublikacjaCurrently, sewage sludge is considered as a biomass, according to the Polish act on renewable energy sources from 20th of February 2015 and its novel version from 19th of July 2019. Possibility to utilize sewage sludge in gasification process is an additional advantage of the negative CO2 emissions power plant (nCO2PP). The work presents results of thermodynamic, ecological, and economical analysis using a zero-dimensional mathematical...
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Pozytywne doświadczenia zakupowe w kreowaniu lojalności nabywczej
PublikacjaDoświadczenie zakupowe to rodzaj mentalnej podróży, pozostawiającej niematerialne wrażenia, w postaci wiedzy i śladu emocjonalnego [69], będące kluczowym elementem w zrozumieniu zachowań konsumentów, jak również istotnych zmian zachodzących we współczesnym marketingu [10]. Cel: Celem głównym badań było ukazanie wpływu pozytywnych doświadczeń zakupowych na kształtowanie satysfakcji i lojalności nabywczej oraz sposobów budowania...
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Ocena wpływu dawki DME na wybrane wskaźniki procesu spalania w dwupaliwowym silniku o zapłonie samoczynnym
PublikacjaPrzedmiotem rozprawy jest analiza wpływu różnej ilości odparowanego DME wprowadzonego do kolektora dolotowego na wybrane wskaźniki spalania DME/ON dla wielu punktów pracy, turbodoładowanego silnika o zapłonie samoczynnym. Jako punkty pracy silnika, wybrano punkty najbardziej reprezentujące cykl jazdy WLTP dla samochodu Volkswagen Golf IV. Analizę procesu współspalania przeprowadzono z wykorzystaniem danych pomiarowych, uzyskanych...
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Effects of biotransport and hydro-meteorological conditions on transport of trace elements in the Scott River (Bellsund, Spitsbergen)
PublikacjaThe shaping of surface water chemistry in the Svalbard Archipelago is strongly dependent on the geology of the catchment and the process of long-range transport of atmospheric pollutants (LRATP). It was found that the dissolved trace elements in the Scott River, which catchment is characterized by a decreasing degree of glaciation, were of the natural origin (i.a. weathering and dissolution of local geological substratum). The...
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Biomechanics of the medial meniscus in the osteoarthritic knee joint
PublikacjaBackground. Increased mechanical loading and pathological response of joint tissue to the abnormal mechanical stress can cause degradation of cartilage characteristic of knee osteoarthritis (OA). Despite osteoarthritis is risk factor for the development of meniscal lesions the mechanism of degenerative meniscal lesions is still unclear. Therefore, the aim of the study is to investigate the influence of medial compartment knee OA...