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Wyniki wyszukiwania dla: SURFACE ACTIVE AGENTS
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Big Data Processing by Volunteer Computing Supported by Intelligent Agents
PublikacjaIn this paper, volunteer computing systems have been proposed for big data processing. Moreover, intelligent agents have been developed to efficiency improvement of a grid middleware layer. In consequence, an intelligent volunteer grid has been equipped with agents that belong to five sets. The first one consists of some user tasks. Furthermore, two kinds of semi-intelligent tasks have been introduced to implement a middleware...
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Selection of derivatisation agents for chlorophenols determination with multicriteria decision analysis
PublikacjaThe paper shows very systematic method of selection of derivatisation agents for a given group of analytes. In this study 8 derivatisation agents are assessed for their capability to derivatise 8 chlorophenols. Multicriteria decision analysis is used to combine many objectives of derivatisation agents selection into single, easy to be interpreted numerical value. Three basic analyses were performed to obtain rankings with the aims...
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Release of Encapsulated Bioactive Compounds from Active Packaging/Coating Materials and Its Modeling: A Systematic Review
PublikacjaThe issue of achieving controlled or targeted release of bioactive compounds with specific functional properties is a complex task that requires addressing several factors, including the type of bioactive, the nature of the delivery system, and the environmental conditions during transportation and storage. This paper deals with extensive reporting for the identification of original articles using Scopus and Google Scholar based...
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Deterministic rendezvous of asynchronous bounded-memory agents in polygonal terrains
PublikacjaTwo mobile agents, modeled as points starting at differentlocations of an unknown terrain, have to meet. The terrain is a polygon with polygonal holes. We consider two versions of this rendezvous problem: exact RV, when the points representing the agents have to coincide at some time, and epsilon-RV, when these points have to get at distance less than epsilon in the terrain. In any terrain, each agent chooses its trajectory, but...
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Neural network agents trained by declarative programming tutors
PublikacjaThis paper presents an experimental study on the development of a neural network-based agent, trained using data generated using declarative programming. The focus of the study is the application of various agents to solve the classic logic task – The Wumpus World. The paper evaluates the effectiveness of neural-based agents across different map configurations, offering a comparative analysis to underline the strengths and limitations...
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Decontaminating Arbitrary Graphs by Mobile Agents: a Survey
PublikacjaA team of mobile agents starting from homebases need to visit and clean all nodes of the network. The goal is to find a strategy, which would be optimal in the sense of the number of needed entities, the number of moves performed by them or the completion time of the strategy. Currently, the field of distributed graph searching by a team of mobile agents is rapidly expanding and many new approaches and models are being presented...
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Entangled rendezvous: a possible application of Bell non-locality for mobile agents on networks
PublikacjaRendezvous is an old problem of assuring that two or more parties, initially separated, not knowing the position of each other, and not allowed to communicate, are striving to meet without pre-agreement on the meeting point. This problem has been extensively studied in classical computer science and has vivid importance to modern and future applications. Quantum non-locality, like Bell inequality violation, has shown that in many...
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Mobile chromatographs and spectrometers for the analysis of chemical warfare agents
PublikacjaThis article describes the technological state of readiness regarding mobile chromatographs and spectrometers and their appiicability for the analysis of chemical warfare agents (CWAs), degradation products, simulants, and precursors.
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Clearing directed subgraphs by mobile agents
PublikacjaWe study several problems of clearing subgraphs by mobile agents in digraphs. The agents can move only along directed walks of a digraph and, depending on the variant, their initial positions may be pre-specified. In general, for a given subset S of vertices of a digraph D and a positive integer k, the objective is to determine whether there is a subgraph H=(V,A) of D such that (a) S is a subset of V, (b) H is the union of k directed...
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Quantum dots conjugates with unsymmetrical bisacridines enhance cytotoxicity of these antitumor compounds in lung cancer cells and have protecting effects on normal cells
PublikacjaBackground: In recent years, with the rapid development of nanotechnology and its extensive applications in the medicine, nanocarriers for anticancer drug delivery have gained a great importance. Spherical semiconductor nanocrystals, frequently called quantum dots (QDs) are very attractive nanomaterials for bioimaging applications and they possess properties as potential candidates for drug carrier. Unsymmetrical bisacridines (UAs),...
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The influence of combination of binding agents on fatigue properties of deep cold in-place recycled mixtures in Indirect Tensile Fatigue Test (ITFT)
PublikacjaThe publication presents fatigue properties of cold recycled mixtures for eight combinations of binding agents (cement and bituminous emulsion). Cold recycled mixtures were evaluated in Indirect Tensile Fatigue Test (ITFT) at the temperature of 20 C in controlled stress mode. As a function of horizontal stress, fatigue life is strongly influenced by combination of the binding agents. When fatigue life is analyzed as a function...
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Quantum strategies for rendezvous and domination tasks on graphs with mobile agents
PublikacjaThis paper explores the application of quantum nonlocality, a renowned and unique phenomenon acknowledged as a valuable resource. Focusing on an alternative application, we demonstrate its quantum advantage for mobile agents engaged in specific distributed tasks without communication. The research addresses the significant challenge of rendezvous on graphs and introduces a distributed task for mobile agents grounded in the graph...
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Antimicrobial molecular nanocarrier–drug conjugates
PublikacjaMany antimicrobial drugs are poorly active against pathogenic microbes causing intracellular infections, such as Mycobacterium tuberculosis or Plasmodium falciparum. On the other hand, several known antimicrobial agents are not effective enough because of their limited cellular penetration. A common feature of both challenges is the inability of an active agent to cross the biological membrane(s). One of the possible approaches...
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Paweł Burdziakowski dr inż.
Osobydr inż. Paweł Burdziakowski jest specjalista w zakresie fotogrametrii i teledetekcji lotniczej niskiego pułapu, nawigacji morskiej i lotniczej. Jest również licencjonowanym instruktorem lotniczym oraz programistą. Głównymi obszarami zainteresowania jest fotogrametria cyfrowa, nawigacja platform bezzałogowych oraz systemy bezzałogowe, w tym lotnicze, nawodne, podwodne. Prowadzi badania w zakresie algorytmów i metod poprawiających...
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Inspired by Nature: The Use of Plant-derived Substrate/Enzyme Combinations to Generate Antimicrobial Activity in situ
PublikacjaThe last decade has witnessed a renewed interest in antimicrobial agents. Plants have received particular attention and frequently rely on the spontaneous enzymatic conversion of an inactive precursor to an active agent. Such two-component substrate/enzyme defence systems can be reconstituted ex vivo. Here, the alliin/alliinase system from garlic seems to be rather effective against Saccharomyces cerevisiae, whilst the glucosinolate/myrosinase...
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Transport of paracetamol in swellable and relaxing polyurethane nanocomposite hydrogels
PublikacjaPolyurethane hydrogels are potentially attractive materials for biomedical applications. They are able to absorb large amount of water, biological fluids or active substances, and thus, they have potential to be used as absorbents or wound-healing dressings. They are also used for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. The presence of...
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Synthetic strategies in construction of organic low molecular-weight carrier-drug conjugates
PublikacjaInefficient transportation of polar metabolic inhibitors through cell membranes of eukaryotic and prokaryotic cells precludes their direct use as drug candidates in chemotherapy. One of the possible solutions to this problem is application of the ‘Trojan horse’ strategy, i.e. conjugation of an active substance with a molecular carrier of organic or inorganic nature, facilitating membrane penetration. In this work, the synthetic...
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Selective Cytostatic and Cytotoxic Anticancer Effects of Bisfunctional Agents: A Strategy for the Design of DNA Binding Agents
PublikacjaVarious agents have been synthesized and proved useful for the National Cancer Institute's anticancer testing as potential new drugs, but most agents suffer side effects from their limited selectivity against cancer cells over healthy ones. Therefore, this paper attempts to describe drugs in terms of the level of tumor cell selectivity which they possess to define the features of mols. that are essential for useful cytotoxicity....
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublikacjaBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Document Agents with the Intelligent Negotiations Capability
PublikacjaThe paper focus is on augmenting proactive document-agents with built -in intelligence to enable them to recognize execution context provided by devices visited durning the business process, and to reach collaboration agreement despite of their conflicting requirements. We propose a solution based on neural networks to improve simple multi-issue negotiation between the document and the device, practically with no excessive cost...
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A Review of Traffic Analysis Attacks and Countermeasures in Mobile Agents' Networks
PublikacjaFor traditional, message-based communication, traffic analysis has been already studied for over three decades and during that time various attacks have been recognised. As far as mobile agents’ networks are concerned only a few, specific-scope studies have been conducted. This leaves a gap that needs to be addressed as nowadays, in the era of Big Data, the Internet of Things, Smart Infrastructures and growing concerns for privacy,...
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Travel agents and destination management organizations: eLearning as a strategy to train tourism trade partners.
PublikacjaThis article offers an overview of the existing online courses run by national destination management organizations (DMOs) in order to better equip travel agents and tour operators in the sales activities of the tourism destinations. These online courses represent one of the B2B offers by DMOs and an interesting opportunity for travel agents, who are trying to find their identity and competitive advantage within the context of...
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Glutathione conjugation of the antitumor-active 1-nitroacridine derivatives compounds C-857 and C-1748 – the major role of glutathione S-transferase M1-1
Dane BadawczeObjectives: C-857 and C-1748 are antitumor-active agents, monomers of unsymmetrical bisacridine derivatives. The aim of this study was to analyze their glutathione (GSH) conjugation in vitro in the presence of glutathione S-transferase (GST) M1-1.
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Nickel phase deposition on V2CTx/V2AlC as catalyst precursors for a dry methane reforming: The effect of the deposition method on the morphology and catalytic activity
PublikacjaDry reforming of methane (DRM) is a promising alternative technology for the production of syngas with simultaneous utilization of two main greenhouse gases (CH4, CO2). However, DRM technology is still an industrially immature process due to the lack of stable and active catalyst. Therefore, the search for new catalytic materials is of great research interest. Recently, MAX and MXenes materials are increasingly being tested as...
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Tomasz Krolikowski dr hab. inż.
OsobyIn 1996, I have graduated from the Faculty of Marine Science of Szczecin University and obtained a master's degree - ocean engineering engineer " - Control and Ocean Engineering Measurements". In 1994 I was hired as an assistant trainee at the Institute of Computer Science Technical University of Szczecin, and after graduating in 1996, I was employed as academic and teaching at the Institute of Computer Science in the Department...
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9,10-Dioxoanthracenyldithiocarbamates effectively inhibit the proliferation of non-small cell lung cancer by targeting multiple protein tyrosine kinases
PublikacjaAnthraquinones have attracted considerable interest in the realm of cancer treatment owing to their potent anticancer properties. This study evaluates the potential of a series of new anthraquinone derivatives as anticancer agents for non-small-cell lung cancer (NSCLC). The compounds were subjected to a range of tests to assess their cytotoxic and apoptotic properties, ability to inhibit colony formation, pro-DNA damage functions,...
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Deterministic rendezvous of asynchronous bounded-memory agents in polygonal terrains
PublikacjaWe consider two versions of the rendezvous problem: exact RV, when the points representing agents have to coincide at some time, and e-RV, when these points have to get at distance less than e in the terrain. In any terrain, each agent chooses its trajectory, but the movements of the agent on this trajectory are controlled by an adversary that may, e.g. speed up or slow down the agent.
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Recent progress in the development of steroid sulfatase inhibitors – examples of the novel and most promising compounds from the last decade
PublikacjaThe purpose of this review article is to provide an overview of recent achievements in the synthesis of novel steroid sulfatase (STS) inhibitors. STS is a crucial enzyme in the biosynthesis of active hormones (including estrogens and androgens) and, therefore, represents an extremely attractive molecular target for the development of hormone-dependent cancer therapies. The inhibition of STS may effectively reduce the availability...
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Arsenic-Based Warfare Agents: Production, Use, and Destruction
PublikacjaSince the beginning of time, civilizations have looked for more creative ways to dominate and defeat their enemies. The rapid development of the chemical industry just before the Second World War started the era of modern chemical weapon production based on poisons, including toxic arsenic compounds. This paper provides a detailed overview of the production, usage and destruction of this dangerous chemical weapon. Milestones include:...
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Novel Functionalization of Boron-Doped Diamond by Microwave Pulsed-Plasma Polymerized Allylamine Film
PublikacjaWe report the novel modification of a hydrogen-terminated polycrystalline boron-doped electrode with a microwave pulsed-plasma polymerized allylamine. Boron-doped diamond (BDD) was coated with a very thin layer of adherent cross-linked, pinhole- and additive-free allylamine plasma polymer (PPAAm) resistant to hydrolysis and delamination and characterized by a high density of positively charged amino groups. The pulsed microwave...
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Other specified bacterial agents as the cause of diseases classified to other chapters - Female, 55 - Tissue image [5050730010502011]
Dane BadawczeThis is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Bilateral Multi-Issue Negotiation Between Active Documents and Execution Devices
PublikacjaMobile document-agents are often in conflict with execution devices when attempting to perform activities of the business process they implement, since preferences of device owners may change depending on their current location and the actual class of the device in use. The paper proposes a bilateral negotiation mechanism based on a simple bargaining game that can effectively resolve such conflicts without any third party support.
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Distributed Evacuation in Graphs with Multiple Exits
PublikacjaWe consider the problem of efficient evacuation using multiple exits. We formulate this problem as a discrete problem on graphs where mobile agents located in distinct nodes of a given graph must quickly reach one of multiple possible exit nodes, while avoiding congestion and bottlenecks. Each node of the graph has the capacity of holding at most one agent at each time step. Thus, the agents must choose their movements strategy...
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Biobójcze wykończenie tkanin
PublikacjaThe problem of nosocomial infections is nothing new. In places, where people, whose immune system is weakened, are gathered and subjected to various kinds of treatments, the risk of infection increases considerably. The use of textiles with biocidal finishing, which contains nanoAg and nanoCu, may give an additional protection against nosocominal infections. This article presents the latest information regarding various methods...
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Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use.
PublikacjaThe acridinone derivates C-1305 and C-1311 are promising antitumor agents with high activity against several experimental cellular and tumor models and which are under evaluation in pre-clinical and early phase clinical trials. Recent evidence from our laboratories has indicated that both compounds were conjugated by several UGT isoforms with the most active being extrahepatic UGT1A10. The present studies were designed to test...
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Oznaczanie tlenu – od metody Winklera do czujników enzymatycznych (Determination of oxygen – from Winkler Method to enzymatic sensor)
PublikacjaMonitoring of dioxygen levels is of utmost importance from the view-point of life processes, medical diagnostics, nutrition and chemical industries. In all these measurements both low and high levels of this element are important. The common methods for the determination of dioxygen are the Winkler method, Clark electrode and pulsoxymeters. A new, already strong field of research can be now recognized – the development of miniaturized...
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Amino Acid Based Antimicrobial Agents – Synthesis and Properties
PublikacjaStructures of several dozen of known antibacterial, antifungal or antiprotozoal agents are based on the amino acid scaffold. In most of them, the amino acid skeleton is of a crucial importance for their antimicrobial activity, since very often they are structural analogs of amino acid intermediates of different microbial biosynthetic pathways. Particularly, some aminophosphonate or aminoboronate analogs of protein amino acids are...
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Time versus space trade-offs for randezvous in trees
PublikacjaTwo identical (anonymous) mobile agents start from arbitrary nodes of an unknown tree and have to meet at some node. Agents move in synchronous rounds: in each round an agent can either stay at the current node or move to one of its neighbors. We consider deterministic algorithms for this rendezvous task. The main result of this paper is a tight trade-off between the optimal time of completing rendezvous and the size of memory...
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Agents in Simulation of Cyberattacks to Evaluate Security of Critical Infrastructures
PublikacjaIn the last years critical infrastructures have become highly dependent on the information technologies and exposed to cyberattacks. Because the effects of the attacks can be detrimental, it is crucial to comprehensively asses the security of the infrastructures' information systems. This chapter describes MAlSim - the simulator of malicious software based on software agents, developed for the needs of a testbed for critical infrastructures...
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APPLIED SURFACE SCIENCE
Czasopisma -
Trimethyl Lock Based Tools for Drug Delivery and Cell Imaging – Synthesis and Properties
PublikacjaTrimethyl lock (TML) systems have become increasingly important in medicinal and bioorganic chemistry, particularly for their roles in the targeted delivery of therapeutic agents and as integral components in fluorogenic probes for cellular imaging. The simplicity and efficiency of their synthesis have established TML systems as versatile platforms for the controlled release of active molecules under particular physiological conditions....
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Phylogenetic relationship and antimicrobial resistance in Escherichia coli isolated from the Reda River and the Oliwski Stream, Northern Poland = Lekooporność i przynależność filogenetyczna szczepów Escherichia Coli izolowanych z rzeki Redy i Potoku Oliwskiego
PublikacjaThe high abundance of fecal bacteria in surface water is usually related to poor agricultural practice, pollution caused by domesticated and wild animals as well as with septic tank failures. Identification of fecal contamination sources seems to be crucial in order to effectively estimate the inherent risk. In this study, the phylogenetic relationship of 30 isolates of E. coli, originated from surface water, was estimated by employing...
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Identification and antimicrobial susceptibility of fecal coliforms isolated from surface water
Publikacjaof 274 fecal coliforms isolated from two watercourses influencing the costal water quality of the gdańsk and the puck bay, 265 were identified as escherichia coli. the remained strains belonged to: acinetobacter spp. (n=1), enterobacter spp. (n=3), klebsiella spp. (n=4) and shigella spp. (n=1). the susceptibility of 222 e. coli was tested against 19 antimicrobial agents: aminoglycosides, carbapenems, cephalosporines, folate antagonists,...
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A multi-agent method for periodicity detection in distributed events
PublikacjaMulti-agent systems working in constantly changing environments may be challenged by instantaneous unavailability of their autonomous agents caused e.g. by limited computing resources. A new method of self-organization of distributed service components is proposed, suitable for multi-agent systems. This method relies on particular agents carrying out separate analyzes of their individual processing loads or other specific events....
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GROUP COMPOSER - System for Modeling Agents’ Team Building for Tasks
PublikacjaMulti-agent systems consist of many autonomous units, called agents, that can interact when trying to achieve their goals. The selection of interaction partners is called team formation. Three basic approaches can be considered to match multi-agent system resources to the problem at hand. To research the properties of different approaches, a software for modeling team formation in multi-agent systems has been created and is presented...
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Pharmacomicrobiomics of cell-cycle specific anti-cancer drugs – is it a new perspective for personalized treatment of cancer patients?
PublikacjaIntestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotrans-formation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobiotics. However, there is another side to the coin. Pharmacotherapeutic agents can significantly modify the microbiota, which consequently affects their efficacy. In this review, we comprehensively...
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BeesyBees: A mobile agent-based middleware for a reliable and secure execution of service-based workflow applications in BeesyCluster
PublikacjaIntegrating distributed services into workflows comes with its own set of challenges, including security, coordination, fault tolerance and optimisation of execution time. This paper presents an architecture and implementation - nicknamed BeesyBees - that allows distributed execution of workflow applications in BeesyCluster using agents. BeesyCluster is a middleware that allows users to access distributed resources as well as publish...
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Treatment innovation using solar/UV In book: The Treatment of Pharmaceutical Wastewater: Innovative Technologies and the Adaptation of Treatment Systems
PublikacjaSince ancient times, sunlight irradiation has been widely used for water purification. Apart from solar water disinfection techniques, UV irradiation is of particular interest when considering the photodegradation of various classes of emerging pollutants. Pharmaceutically active compounds are one of the largest classes of micropollutants. The main sources of these contaminants in wastewater and aqueous environments are households,...
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Natural carbon-based quantum dots and their applications in drug delivery: A review
PublikacjaNatural carbon based quantum dots (NCDs) are an emerging class of nanomaterials in the carbon family. NCDs have gained immense acclamation among researchers because of their abundance, eco-friendly nature, aqueous solubility, the diverse functionality and biocompatibility when compared to other conventional carbon quantum dots (CDs).The presence of different functional groups on the surface of NCDs such as thiol, carboxyl, hydroxyl,...
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Cold-adapted bacterial lipolytic enzymes and their applications
PublikacjaLipolytic enzymes, esterases and lipases catalyze the hydrolysis and transesterification of fatty acid esters. This class of enzymes is the most important group of biocatalysts for biotechnological applications. From this perspective, coldactive lipolytic enzymes from cold adapted bacteria display attractive properties for some industrial purposes, including high catalytic activity at low temperatures and low thermostability. To...