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Wyniki wyszukiwania dla: INFLATION FORECAST TARGETING
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Starogard Gdański 2019, Aleja Niepodległości, Pomorska and Mikołaja Kopernika street - video data - pedestrian, bicycles, vehicles.
Dane BadawczeThe data contain video traffic data (pedestrian, cyclists, vehicles) registered at Aleja Niepodległości street. Date 13.06.2019, 6:00-18:00. The video camera was installed around intersections at Aleja Niepodległości – Galeria Neptun street and Pomorska – Mikołaja Kopernika street. Camera was mounted on 7-meter-high mast.
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Net electricity production by fuel (2006-2030)
Dane BadawczeThis dataset presents the current structure of electricity sources and a forecast of the share of individual fuels in electricity production in Poland until 2030. First of all, it should be noted the constantly growing supply of electricity. It is related to the continuous economic development, increasing consumption both by enterprises and households.
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
Publikacjanthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones. BS-154, the most potent derivative, had IC50 values close to 1 nM, however, it was toxic in animal studies. Here, we characterize another...
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The multivariate multilevel analisis of different regional factors impact on road saferty in european country regions = Wielopoziomowa analiza wieloczynnikowa wpływu różnych charakterystyk regionalnych na poziom bezpieczeństwo ruchu w regionach krajów europejskich
PublikacjaIn this research, the effect of the European regional differences on the risk of been killed in road accident in these regions is investigated. Factors which differentiate regions can be described as automotive, economic, infrastructural, demographic, geographic. Analyzed risk, counted as regional fatality rate was modeled by the Poisson model. Because of regional diversity of Poisson distribution parameters, the Poisson distribution...
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Application of Multivariate Analysis Methods in Welding Engineering
PublikacjaPhenomena and processes taking place during welding are usually very complex and, for this reason, should be described using multivariate methods. The article discusses the methodological basis and selected application areas as regards the solving of welding problems using statistical multivariate methods. In addition, the article presents exemplary applications of the design of experiment, multiple regression analysis, cluster...
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Fuel price, income and road safety as determinants of the level of the population’s economic well-being in Poland
PublikacjaThe opportunity to travel is one of the most favorite human activities, given that on a trip a person gets new knowledge, impressions and positive emotions. Recreational trips occupy a prominent place in the concept of the economics of happiness, and the study of factors that influence decision-making regarding travel is important for forecasting the number of tourists, infrastructure development, income and expenses of businesses...
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ANALIZA PRZEPUSTOWOŚCI WYBRANEGO UKŁADU TOROWEGO W PRZESTRZENI CZĘŚCIOWO – UPORZĄDKOWANEJ
PublikacjaNa sieci kolejowej istotny wpływ na płynność ruchu mają odpowiednio usytuowane odcinki odstępowe. Z podobną sytuacją mamy do czynienia przy modernizacji stacji kolejowych i tworzeniu nowych rozwiązań, w których należy uwzględnić prognozy rozwoju ruchu na danym elemencie sieci kolejowej. Jednak w przypadku stacji sytuacja staje się dużo bardziej skomplikowana i kosztowna, gdyż poprawa przepustowości wymaga istotnych zmian organizacyjnych...
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Analysis and bioanalysis: an effective tool for data collection of environmental conditions and processes
PublikacjaReliable information that allows us to estimate the state of the environment and to forecast changes in the ecosystem are constantly required. Increasing environmental consciousness and dynamic development of analytical techniques are the main reasons for determining the wide range of pollutants occurring at very low concentrations in complex matrix samples. The presence and concentration of many of those pollutants in the environment...
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Framework for extracting rails and setting-out railway line axis based on UAV photogrammetric measurements
Dane BadawczeTechnical diagnostics enables assessing the current technical condition of a railway line and adjacent infrastructure, and to forecast its changes over a specific time horizon. One of its elements is the periodic monitoring of rail position and their geometry. The data set presents a new framework for the setting-out of a railway track axis. The process...
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Energy Security of Polish Consumers in 2004-2021
Dane BadawczeEnergy security is one of the most important components of economic security. It is influenced not only by access to energy sources and the economic situation of the state and the individual consumer. In the years 2004–2021, energy security of the individual consumer in the economic dimension significantly improved. This was due to several factors:1....
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CUTTING POWER FORECASTING WHILE WOOD SAWING: FRACTURE MECHANICS APPROACH AND AXELSSON’S MODEL COMPARISON
PublikacjaIn the classical approach, energetic effects (cutting forces and cutting power) of wood sawing process are generally calculated on the basis of the specific cutting resistance, which is in the case of wood cutting the function of more or less important factors. On the other hand, cutting forces (power) could be considered from a point of view of modern fracture mechanics. Another way is to forecast cutting power consumption on...
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A multi-agent method for periodicity detection in distributed events
PublikacjaMulti-agent systems working in constantly changing environments may be challenged by instantaneous unavailability of their autonomous agents caused e.g. by limited computing resources. A new method of self-organization of distributed service components is proposed, suitable for multi-agent systems. This method relies on particular agents carrying out separate analyzes of their individual processing loads or other specific events....
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Road safety information system in Poland - supporting tools and their development
PublikacjaAs a signatory to the UN Declaration on road safety and member of the EU, Poland has an obligation to comply with relevant EU policies and in particular to halve the overall number of road deaths by 2020. To monitor the progress in reaching the targets, the road safety situation must be evaluated and its processes understood. For this purpose regional and national road safety observatories were launched in Poland, which triggered...
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X-ray and UV Radiation Damage of dsDNA/Protein Complexes
PublikacjaRadiation and photodynamic therapies are used for cancer treatment by targeting DNA. However, efficiency is limited due to physico-chemical processes and the insensitivity of native nucleobases to damage. Thus, incorporation of radio- and photosensitizers into these therapies should increase both efficacy and the yield of DNA damage. To date, studies of sensitization processes have been performed on simple model systems, e.g.,...
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A METHOD OF TRUST MANAGEMENT IN WIRELESS SENSOR NETWORKS
PublikacjaThe research problem considered in this paper is how to protect wireless sensor networks (WSN) against cyber-threats by applying trust management and how to strengthen network resilience to attacks targeting the trust management mechanism itself. A new method, called WSN Cooperative Trust Management Method (WCT2M), of distributed trust management in multi-layer wireless sensor networks is proposed and its performance is evaluated....
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Numerical Analysis of Mice Carotid Arteries’ Response Emphasizing the Importance of Material Law Constants’ Validation
PublikacjaIn this paper, a detailed validation of the passive material properties of mice carotid arteries and constants of the Fung and Holzapfel hyperelastic material laws is conducted by means of static nonlinear FEM analyses. The response of the carotid arteries in an inflation test is studied here for the following mouse models: wild-type, mdx, sgcd−/−, Eln+/+, Eln+/−, Fbln5+/+, and Fbln5−/−. All FEM computations are conducted on models...
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Metodologia budowy modelu sieci połączonych systemów UCTE i obliczania wskaźników służączych do oceny zagrożeń współpracy systemu europejskiego.
PublikacjaLiberalizacja rynku energii doprowadziła do znacznego zwiększenia obrotów energią elektryczną pomiędzy systemami elektroenergetycznymi. Operatorzy Systemów Przesyłowych są zobligowania do prognozowania rozpływow mocy w połączonych systemach i identyfikowania zagrożeń systemowych nawet w cyklach dobowych - na dzień nastepny. w referacie zostana omówione elementy występujące w procesie tworzenia modelu sieci przesyłowej systemów...
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Predicting the impact of traffic–induced vibrations on buildings using artificial neural networks
PublikacjaTraffic–induced vibrations may constitute a considerable load to a building, cause cracking of plaster, cracks in load–bearing elements or even a global structural collapse of the whole structure [1-4]. Vibrations measurements of real structures are costly and laborious, not justified in all cases. The aim of the paper is to create an original algorithm, to predict the negative dynamic impact on the examined residential building...
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublikacjaHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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Pursuing the Deep-Learning-Based Classification of Exposed and Imagined Colors from EEG
PublikacjaEEG-based brain-computer interfaces are systems aiming to integrate disabled people into their environments. Nevertheless, their control could not be intuitive or depend on an active external stimulator to generate the responses for interacting with it. Targeting the second issue, a novel paradigm is explored in this paper, which depends on a passive stimulus by measuring the EEG responses of a subject to the primary colors (red,...
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Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2
PublikacjaIn view of recent global pandemic the 3-alkynyl substituted 2-chloroquinoxaline framework has been explored as a potential template for the design of molecules targeting COVID-19. Initial in silico studies of representative compounds to assess their binding affinities via docking into the N-terminal RNA-binding domain (NTD) of N-protein of SARS-CoV-2 prompted further study of these molecules. Thus building of a small library of...
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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublikacjaColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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Comparison of the Efficiency of Hetero- and Homogeneous Catalysts in Cellulose Liquefaction
PublikacjaBiomass liquefaction is a well-known and extensively described process. Hydrothermal processes are well understood and can be used in the fuel industry. The use of organic solvents can result in full-fledged products for use in the synthesis of polyurethanes. The plastics industry, including polyurethanes, is targeting new, more environmentally friendly solutions. One of these is the replacement of petrochemical polyols with compounds...
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Communication and Documentation Practices in Agile Requirements Engineering: A Survey in Polish Software Industry
PublikacjaRequirements engineering, system analysis and other analytical activities form the basis of every IT project. Such activities are not clearly defined in Agile development methods, but it does not mean that they are absent in an agile project. The aim of our work was to determine which practices related to requirements-related communication and which requirements documenting techniques are used in agile software projects. For this...
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Grand Challenges on the Theory of Modeling and Simulation
PublikacjaModeling & Simulation (M&S) is used in many different fields and has made many significant contributions. As a field in its own right, there have been many advances in methodologies and technologies. In 2002 a workshop was held in Dagstuhl, Germany, to reflect on the grand challenges facing M&S. Ten years on, a series of M& S Grand Challenge activities are marking a decade of progress and are providing an opportunity to reflect...
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Tyre/road noise measurements on ISO tracks according to the UNECE Regulation 117
PublikacjaWithin the Polish-Norwegian research project ELANORE, a limited Round Robin Test has been performed on 3 ISO tracks in Northern Europe. The basic objective of the project is to improve the EU directive on labelling of tyres for noise and rolling resistance, and this directive is based on the measurement procedures defined in the UN ECE Reg.117. The same test car, test tyres and measurement equipment as well as personnel were used...
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Economic crisis in Croatia
PublikacjaCroatia is becoming the 28th member of the European Union on July 1st, 2013. Croatia has gone a long way from a socialistic republic to an independent country recognized as one of the economic tigers of the Western Balkans in the first decade of the 21st century. Croatia has been hit by a global crisis which turned out to be a huge external shock for the region of the Western Balkans. Although it does not enter the economy through...
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Comparison of Traffic Flow Models with Real Traffic Data Based on a Quantitative Assessment
PublikacjaThe fundamental relationship of traffic flow and bivariate relations between speed and flow, speed and density, and flow and density are of great importance in transportation engineering. Fundamental relationship models may be applied to assess and forecast traffic conditions at uninterrupted traffic flow facilities. The objective of the article was to analyze and compare existing models of the fundamental relationship. To that...
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Impact of digital technologies on reliability of risk forecasting models - case study of enterprises in three global financial market regions
PublikacjaThis chapter focuses on the evaluation of impact of ICT on reliability of financial risk forecasting models. Presented study shows how the development of ICT can improve the effectiveness of such models. Determining a firm’s financial risk is one of the most interesting topics for investors and decision-makers. The multifaceted goal of the presented research is to separately estimate five traditional statistical and five soft computing...
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The Dynamics of Trade Relations between Ukraine and Romania: Modelling and Forecasting
PublikacjaThe article examines the monthly dynamics of exports, imports and balance of trade between Ukraine and Romania in the period from 2005 to 2021. Time series from 2015 to 2021 were used for modelling and forecasting (since the date the European Union–Ukraine Association Agreement took effect). Adequate models of the dynamics series of the Box-Jenkins methodology were built: additive models with seasonal component ARIMA (Autoregressive...
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Simulations of the Derecho Event in Poland of 11th August 2017 Using WRF Model
PublikacjaThis series contains datasets related to the forecasting of a severe weather event, a derecho, in Poland on 11 August 2017. The simulations were conducted using the Weather Research and Forecasting (WRF) model version 4.2.1 with different initial and boundary conditions of the pressure and model levels derived from 5 global models: Global Forecast System (GFS), Global Data Assimilation System (GDAS), European Centre for Medium-Range...
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Methods of liquid biofuels production - the bioethanol example.
PublikacjaEthanol is used in chemical and food industry, mainly either in the synthesis or as a solvent. The newest application of ethanol is as a fuel. This alcohol, produced on an industrial scale from crop waste, is widely known under the name bioethanol. It could be used as a fuel by itself or in a mixture with gasoline. Today, there are several technologies for bioethanol production known. The relatively simple method of obtaining bioethanol...
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METHODS OF LIQUID BIOFUEL PRODUCTION – THE BIOETHANOL EXAMPLE
PublikacjaEthanol is used in chemical and food industry, mainly either in the synthesis or as a solvent. The newest application of ethanol is as a fuel. This alcohol, produced on an industrial scale from crop waste, is widely known under the name bioethanol. It could be used as a fuel by itself or in a mixture with gasoline. Today, there are several technologies for bioethanol production known. The relatively simple method of obtaining bioethanol...
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Noise and Rolling Resistance Properties of Various Types of Winter Tyres Compared to Normal Car Tyres
PublikacjaTo cope with winter weather conditions, potentially including snow and ice, it is common to use winter tyres, or ”all-seasons” tyres assumed to be safe both in summer and winter. In some northern countries, winter tyres are mandatory. Traditionally, it has been assumed that winter tyres are noisier than normal tyres (here called summer tyres) and winter tyres equipped with studs are assumed to be very noisy.This paper presents...
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Nonlinear material identification of heterogeneous isogeometric Kirchhoff–Love shells
PublikacjaThis work presents a Finite Element Model Updating inverse methodology for reconstructing heterogeneous materialdistributions based on an efficient isogeometric shell formulation. It uses nonlinear hyperelastic material models suitable fordescribing incompressible material behavior as well as initially curved shells. The material distribution is discretized by bilinearelements such that the nodal values...
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Quantifying the effective mobilized RAP content during hot in-place recycling techniques
PublikacjaThe utilization of in-place recycling techniques is capable of consuming 100% reclaimed asphalt pavement (RAP). Hot in-place recycling (HIR) is one of the promising techniques to rehabilitate the pavements suffering from minor cracking issues through heat scarification, additive injecting, mechanical mixing, and compacting. However, the main concern of using 100% RAP in HIR remains as how much RAP can be activated and mobilized...
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INNOVATIVE RUN FLAT SYSTEMS
PublikacjaOne of the most essential threats to the mobility of wheeled vehicles is their relatively high sensitivity to tire damage. Tires can be damaged as a result at vehicle-targeting fire, after running on a mine or an improvised charge. The purpose of the article is to analyze the current technical solutions in wheeled vehicle tires, allowing for the unobstructed use of the vehicle despite the damage of one or several tires (RUN FLAT...
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LONG-TERM RISK CLASS MIGRATIONS OF NON-BANKRUPT AND BANKRUPT ENTERPRISES
PublikacjaThis paper investigates how the process of going bankrupt can be recognized much earlier by enterprises than by traditional forecasting models. The presented studies focus on the assessment of credit risk classes and on determination of the differences in risk class migrations between non-bankrupt enterprises and future insolvent firms. For this purpose, the author has developed a model of a Kohonen artificial neural network to...
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The Possibility of Phase Change Materials (PCM) Usage to Increase Efficiency of the Photovoltaic Modules
PublikacjaSolar energy is widely available, free and inexhaustible. Furthermore this source of energy is the most friendly to the environment. For direct conversion of solar energy into useful forms like of electricity and thermal energy, respectively photovoltaic cells and solar collectors are being used. Forecast indicate that the first one solution will soon have a significant part in meeting the global energy demand. Therefore it is...
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Machine-Learning Methods for Estimating Performance of Structural Concrete Members Reinforced with Fiber-Reinforced Polymers
PublikacjaIn recent years, fiber-reinforced polymers (FRP) in reinforced concrete (RC) members have gained significant attention due to their exceptional properties, including lightweight construction, high specific strength, and stiffness. These attributes have found application in structures, infrastructures, wind power equipment, and various advanced civil products. However, the production process and the extensive testing required for...
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A survey on network resiliency methodologies against weather-based disruptions
PublikacjaDue to the increasing dependence on network services of our society, research has recently been concentrating on enhancing traditional protection strategies to withstand large-scale failures, as in case of disaster events. The recently-formed EU-funded RECODIS project aims at coordinating and fostering research collaboration in Europe on disaster resiliency in communication networks. In particular, the Working Group (WG) 2 of the...
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Simulation of the derecho event in Poland of 11th August 2017 using the WRF model and GFS data as initial conditions
Dane BadawczeThis series contains datasets related to the forecasting of a severe weather event, a derecho, in Poland on 11 August 2017. The simulations were conducted using the Weather Research and Forecasting (WRF) model version 4.2.1 with initial and boundary conditions from Global Forecast System (GFS). Simulation was performed for two starting hours: at 00:00...
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Ruchotwórczość wielkopowierzchniowych obiektów handlowych trzeciej generacji na przykładzie Trójmiasta
PublikacjaWielkopowierzchniowe obiekty (handlowe, usługowe itp.) generują ruch o dużych natężeniach, które często przekraczają możliwości przepustowe przyległego układu ulicznego. Wpływają w ten sposób na znaczne pogorszenie się warunków ruchu w najbliższym otoczeniu obiektu i zakłócenia w prawidłowym funkcjonowaniu systemu transportowego miasta. Wobec braku polskich doświadczeń konieczne jest badanie wpływu wybranych czynników demograficznych,...
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DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
PublikacjaThe human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylated region (DMR) encompassing HLA-DRB1 exon 2 is particularly affected and displays methylation-sensitive regulatory properties in vitro. Causal inference and Mendelian randomization...
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From tryptophan to novel mitochondria-disruptive agent, synthesis and biological evaluation of 1,2,3,6-tetrasubstituted carbazoles
PublikacjaMitochondrial targeting plays an important role in anticancer therapy. The Mn(III)-promoted cyclization of 5- (1H-indol-3-yl)-3-oxopentanoic acid allow to obtain novel substituted carbazole derivatives that can act as mitochondria-disruptive agents. The starting materials used for the synthesis of these new aminocarbazoles are oxopentanoate derivatives of tryptophan. The scope and limitation of this method of synthesis are determined...
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EASY ACCESS TOOL FOR SMALL INTERFERING RNA (siRNA) DATA
PublikacjaFor many decades it was an accepted dogma of molecular genetics that the expression of genes is a “one-way-road” leading only in one direction from DNA to RNA to proteins. Recent discoveries in modern molecular genetics have challenged this dogma showing that specific RNA molecules play a central role in controlling the activity of genes by changing the structure of DNA sequences, targeting other RNAs for degradation or blocking...
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Novel Complementary Multiple Concentric Split Ring Resonator for Reliable Characterization of Dielectric Substrates with High Sensitivity
PublikacjaAccurate characterization of dielectric substrates with high sensitivity remains an important challenge in a variety of industrial applications. This paper proposes an innovative strategy to address this challenge by developing and optimizing a unique Complementary Multiple Concentric Split Ring Resonator (CMC-SRR). The major goal is to propose a sensor design with increased sensitivity and reliability for dielectric characterization....
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Optimization issues in distributed computing systems design
PublikacjaIn recent years, we observe a growing interest focused on distributed computing systems. Both industry and academia require increasing computational power to process and analyze large amount of data, including significant areas like analysis of medical data, earthquake, or weather forecast. Since distributed computing systems – similar to computer networks – are vulnerable to failures, survivability mechanisms are indispensable...
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Analiza możliwości wzrostu udziału transportu zbiorowego w wojewódzkich przewozach pasażerskich na przykładzie województwa pomorskiego
PublikacjaPodział zadań przewozowych pomiędzy dostępne środki transportu jest jednym z kluczowych wyzwań przy opracowaniu Planów Transportowych w regionach. Stan aktualny i prognozy prowadzone na obszarze Unii Europejskiej wskazują, że w najbliższych latach dominującym środkiem transportu pasażerskiego będzie samochód osobowy z zarysowującą się tendencją wzrostową. Dlatego bardzo istotnym działaniem przy budowie zintegrowanego systemu transportu...
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Extracting functional groups of ALLINI to design derivatives of FDA‐approved drugs: Inhibition of HIV‐1 integrase
PublikacjaHIV‐1 integrase (IN) is crucial for integration of viral DNA into the host genome and a promising target in development of antiretroviral inhibitors. In this work, six new compounds were designed by linking the structures of two different class of HIV‐1 IN inhibitors (active site binders and allosteric IN inhibitors (ALLINIs)). Among newly designed compounds, INRAT10b was found most potent HIV‐1 IN inhibitor considering different...