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Wyniki wyszukiwania dla: DRUG DELIVERY SYSTEM
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Radio system for monitoring and acquisition of data from traffic enforcement cameras - features and assumptions of the system
PublikacjaThe study presents the architecture and selected functional assumptions of Radio System for Monitoring and Acquisition of Data from Traffic Enforcement Cameras (RSMAD). Ultimately, the system will be used for transmission and archiving image data of traffic offenses, but can also perform other duties related to traffic safety. Implementation of the RSMAD system will facilitate, inter alia, issuing the fine process and supervision...
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Asynchronous phase-location system
PublikacjaThis paper presents concept and implementation of digital phase-location system, designed as a navigational aid for marine applications. The main feature of the proposed system is the ability to work in both synchronous mode, with one master station and set of slave stations synchronised with master, and in asynchronous mode with independent clocking of all stations.
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Intercalation complex of imidazoacridinone C-1311, a potential anticancer drug, with DNA helix d(CGATCG)2: stereostructural studies by 2D NMR spectroscopy.
PublikacjaImidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial stage of its action C-1311 forms a relatively stable intercalation complex with DNA, yet it has shown no base-sequence specificity while binding to DNA. In this paper, the d(CGATCG)2:C-1311...
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Energy Management of Microgrid System
PublikacjaW artykule przedstawiono system sterowania rozproszonych źródeł energii (DER) w oparciu o protokół Ethernet POWERLINK. Autorzy opracowali metody komunikowania się z systemu Zarządzania Energią z przekształtnikami energoelektronicznymi w system zwany mikrosiecią (Microgrid). W artykule przedstawiono optymalny podział mocy pomiędzy źródłami wytwórczymi a obciążeniem. System ten składa się z: kogeneratora z silnikiem na gaz ziemny...
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Maciej Szczodrak dr inż.
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The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
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Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublikacjaThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
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Acinetobacter baumannii isolated from hospital‐acquired infection: biofilm production and drug susceptibility
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Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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Cisplatin filled multiwalled carbon nanotubes – a novel molecular hybrid of anticancer drug container
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Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method
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New Life of an Old Drug: Caffeine as a Modulator of Antibacterial Activity of Commonly Used Antibiotics
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The Current Use of Mass Spectrometry in Combination with Other Separation Techniques in Drug Discovery Arena
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Glucosamine-6-phosphate synthase,a novel target for antifungalagents.Molecular modelling studies in drug design
PublikacjaPraca dotyczy modelowania zarówno samych inhibitorów syntazy glukozamino-6-fosforanu jak i ich oddziaływania z obydwiema domenami tego enzymu. Enzym syntaza glukozamino-6-fosforanu został zaproponowany jako nowy cel molekularny w chemoterapii infekcji grzybowych. Zaprojektowano i zsyntezowano szereg inhibitorów tego enzymu - potencjalnych nowych leków przeciwgrzybowych. Dzięki modelowaniu molekularnemu udało się wyjaśnić mechanizm...
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System przetwarzania testów egzaminacyjnych.
PublikacjaW pracy zaprezentowano wykonany przez autorów system AATE, służący do automatycznej analizy testów egzaminacyjnych. System daje możliwość przetwarzania trzech rodzajów ankiet i składa się z trzech modułów: edycji arkuszy, analizy dokumentów i prezentacji wyników. W pracy zamieszczono przykładowe formularze egzaminacyjne, schemat blokowy edytora testów oraz wyniki przeprowadzonych eksperymentów.
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Two-Level Multivariable Control System of Dissolved Oxygen Tracking and Aeration System for Activated Sludge Processes
PublikacjaThe problem of tracking dissolved oxygen is one of the most complex and fundamental issues related to biological processes. The dissolved oxygen level in aerobic tanks has significant influence on behaviour and activity of microorganism inhabiting the plant. Aerated tanks are supplied with air from an aeration system (blowers, pipes, throttling valves, diffusers). It is a complex dynamic system governed by nonlinear hybrid dynamics....
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Music Recommendation System
PublikacjaThe paper focuses on optimization vector content feature for the music recommendation system. For the purpose of experiments a database is created consisting of excerpts of music les. They are assigned to 22 classes corresponding to dierent music genres. Various feature vectors based on low-level signal descriptors are tested and then optimized using correlation analysis and Principal Component Analysis (PCA). Results of the experiments...
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Numerical investigations of the engine cooling system in a small power vesel pod propulsion system
PublikacjaThe development of electronics and electrotechnology enabled to put electric motors of the alternating current in the pod and to use them for the main drive of ships. A lot of heat which must be picked up from the system is a problem which is turning up at applying the system of this type. Many big ships lately contended with these problems. Building the small propeller for the boat powered with solar power we decided to check...
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A decision-making system supporting selection of commanded outputs for a ship's propulsion system with a controllable pitch propeller
PublikacjaThe ship's operators have to make decisions regarding the values of commanded outputs (commanded engine speed and pitch ratio) which ensure maximum vessel speed and minimum fuel consumption. Obviously, the presented decision problems are opposed. Therefore, there is a need for a compromise solution that enables more flexible vessel voyage planning. This paper deals with development of a computer-aided system supporting selection...
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A System for Heart Sounds Classification
PublikacjaThe future of quick and efficient disease diagnosis lays in the development of reliable non-invasive methods. As for the cardiac diseases – one of the major causes of death around the globe – a concept of an electronic stethoscope equipped with an automatic heart tone identification system appears to be the best solution. Thanks to the advancement in technology, the quality of phonocardiography signals is no longer an issue. However,...
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Concept of an Innovative Autonomous Unmanned System for Bathymetric Monitoring of Shallow Waterbodies (INNOBAT System)
PublikacjaBathymetry is a subset of hydrography, aimed at measuring the depth of waterbodies and waterways. Measurements are taken inter alia to detect natural obstacles or other navigational obstacles that endanger the safety of navigation, to examine the navigability conditions, anchorages, waterways and other commercial waterbodies, and to determine the parameters of the safe depth of waterbodies in the vicinity of ports, etc. Therefore,...
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The project of pull system for storehouse and production line in a company provides electronics
PublikacjaThe chapter below presents how to reduced delivery of the material to production by using a "Kanban schedule board" and related tools from 48 hours and 59 minutes to 41 minutes in a company provides electronics. The solution was found through analysis of the current way of supplying stands and using Just In Time idea, the reduction of ''muda''. To solve the problem was used Kanban card", which has the shape of two triangles joined...
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Mobilny system do detekcji obiektów ferromagnetycznych z magnetometrami pompowanymi optycznie
PublikacjaW pracy przedstawiono mobilny system do detekcji obiektów ferromagnetycznych. Każdy obiekt ferromagnetyczny zaburza w swoim otoczeniu równomierność pola magnetycznego Ziemi. Zaburzenie to może być zmierzone za pomocą precyzyjnych magnetometrów. W prezentowanym mobilnym systemie zastosowano magnetometry pompowane optycznie pracujące w układzie różnicowym. W pracy opisano magnetometryczny system do detekcji obiektów ferromagnetycznych,...
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Correction to “Emerging Anticancer Activity of Candidal Glucosamine-6-Phosphate Synthase Inhibitors upon Nanoparticle-Mediated Delivery”
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Twenty‐four‐hour and conventional blood pressure components and risk of preterm delivery or neonatal complications in gestational hypertension
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The Prison System Review
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Agricultural products' storage control system
PublikacjaThe paper discusses the idea and the design of a remote control system for storage management of agricultural products which temperature may rise as the result of biological processes during the storage. An actual potatoes storehouse is discussed as an application for the proposed automation system. Because of existing buildings and infrastructure at the farm, wireless data transfer system has been proposed for communication between...
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INVESTIGATION INTO INTERFEROMETRIC SONAR SYSTEM ACCURACY
PublikacjaThe results of the accuracy measurements of phase differencing bathymetric sonar (PDBS) system in shallow waters are presented in the article. The measurement results were compared with the theoretical calculations for sonar system accuracy and international standards for hydrographic surveys. The proposed formulas enable to assess a priori sonar system performance using system quality factor (SQF), which takes into account influence...
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Asynchroniczny system fazolokacyjny
PublikacjaArtykuł zawiera opis zasady działania oraz budowy prototypu cyfrowego systemu fazolokacyjnego. System ten został zaprojektowany do obsługi nawigacji morskiej, przy czym jego cechą charakterystyczną jest możliwość pracy zarówno w trybie synchronicznym, z wyróżnioną stacją główną i zestawem stacji podległych, jak i w trybie asynchronicznym, w którym wszystkie stacje bazowe są taktowane niezależnie z własnych generatorów wzorcowych....
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Gesture-based computer control system
PublikacjaIn the paper a system for controlling computer applications by hand gestures is presented. First, selected methods used for gesture recognition are described. The system hardware and a way of controlling a computer by gestures are described. The architecture of the software along with hand gesture recognition methods and algorithms used are presented. Examples of basic and complex gestures recognized by the system are given.
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Neurocontrolled Car Speed System
PublikacjaThe features of the synthesis of neural controllers for the car speed control system are considered in this article. The task of synthesis is to determine the weight coefficients of neural networks that provide the implementation of proportional and proportional-integralderivative control laws. The synthesis of controllers is based on an approach that uses a reversed model of the standard. A model of the car speed control system with...
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Asynchronous Wide Area Multilateration System
PublikacjaA new method for a location service in the wide area multilateration (WAM) system is outlined. This method, which is called asynchronous WAM (AWAM), enables calculation of the geographical position of an aircraft without knowledge of relative time differences (RTDs) between measuring ground stations (sensors). The AWAM method is based on the measurement of round trip times (RTTs) between the aircraft and the serving ground station,...
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DRUG AND CHEMICAL TOXICOLOGY
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DRUG METABOLISM AND DISPOSITION
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DRUG DEVELOPMENT RESEARCH
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DRUG METABOLISM REVIEWS
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Microgrid Energy Management System
PublikacjaIn the era of rapid development of "green energy” and storage devices, microgrids implemented in line with the concept of distributed generation can be an effective form of power management. There is a need for an efficient, optimal and reliable control of the combined infrastructure. The article presents a flexible, configurable microgrid's resources control system, which executes the task of meeting the electricity demand of...
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Asynchronous Networked Estimation System for Continuous Time Stochastic Processes
PublikacjaIn this paper we examine an asynchronous networked estimation system for state estimation of continuous time stochastic processes. Such a system is comprised of several estimation nodes connected using a possibly incomplete communication graph. Each of the nodes uses a Kalman filter algorithm and data from a local sensor to compute local state estimates of the process under observation. It also performs data fusion of local estimates...
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Voice Multilateration System
PublikacjaThis paper presents an innovative method of locating airplanes, which uses only voice communication between an air traffic controller and the pilot of an aircraft. The proposed method is described in detail along with its practical implementation in the form of a technology demonstrator (proof of concept), included in the voice communication system (VCS). A complete analysis of the performance of the developed method is presented,...
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Modelling of Geared Multi-Rotor System
PublikacjaIn the paper the method of modelling a speed-varying geared rotor system is presented. The proposed approach enables us to obtain an accurate low-order lumped parameter representation of the investigated system. The final model consists of reduced modal models of an undamped beam/torsional shaft system as well as a spatially lumped model of other linear and nonlinear phenomena including gear mesh interaction.
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Dlaczego system zarządzania przestrzenią?
PublikacjaArtykuł zawiera rozważania dotyczące konieczności i możliwości integracji wielu instrumentów gospodarowania przestrzenią w jeden system, budowany dla potrzeby zarządzania zrównoważonym rozwojem miasta.
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System transportu pasażerskiego, P, STW, sem. 05, zimowy 22/23
Kursy OnlinePrzedmiot związany jest z obsługą rynku przewozów pasażerskich w rejonie Europy oraz świata, szczególnie w rejonie Morza Bałtyckiego, Śródziemnego, Północnego oraz świata w zakresie przewozów promowych oraz ruchu wycieczkowego.
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System transportu pasażerskiego, P, ZLwT, sem. 05, zimowy 22/23
Kursy OnlinePrzedmiot związany jest z obsługą rynku przewozów pasażerskich w rejonie Europy oraz świata, szczególnie w rejonie Morza Bałtyckiego, Śródziemnego, Północnego oraz świata w zakresie przewozów promowych oraz ruchu wycieczkowego.
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System bezpieczeństwa narodowego RP.
PublikacjaSystem bezpieczeństwa narodowego RP1. struktura systemu2.strategia bezpieczeństwa narodowego RP3. zarządzanie kryzysowe- podstawa prawna działania- struktura organizacyjna i kompetencje- realizowana strategia działania4. podsumowanie
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Emotion monitoring system for drivers
PublikacjaThis article describes a new approach to the issue of building a driver monitoring system. Actual systems focus, for example, on tracking eyelid and eyebrow movements that result from fatigue. We propose a different approach based on monitoring the state of emotions. Such a system assumes that by using the emotion model based on our own concept, referred to as the reverse Plutchik’s paraboloid of emotions, the recognition of emotions...
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Radar data fusion in the STRADAR system
PublikacjaThe main task of the Polish Border Guard is protection of the country’s border which requires utilization of multimedia surveillance systems automatically gathering, processing and sharing various data. The paper presents such a system developed for the Maritime Division of the Polish Border Guard within the STRADAR project and the problem of fusion of radar data in this system. The system, apart from providing communication means,...
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The Impact of Wind Generation on the Transmission System
PublikacjaThis article has been published to investigate the im-pact of the wind power on the power system- this is a system dependent issue that requires to perform sys-tem specific impact study. This paper discusses the impact of power flow, short circuit current, power quali-ty, voltage stability and the power system during the connection of a wind farm into transmission system. W referacie omówiono wpływ farm wiatrowych na pracę systemu...
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Monitoring system of the road embankment
PublikacjaThe paper presents the monitoring system of the embankment supported on concrete columns and overlaid by a load transfer platform (LTP) with the embedded steel grid. This field investigation was to study the complex inter-action between the columns, the LTP layer, and steel reinforcement via full-scale in situ measurements during erection of the embankment. The study was focused on the behaviour of steel reinforcement and the behaviour...
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Wireless paging system
PublikacjaAssistance to patients at hospitals and nursing homesoften encounters problems related to obtaining information onthe current needs of the patient. Traditionally, patient informshospital stuff by wire and wireless paging systems. WirelessPaging Systems allow one to overcome the limitations of theirwire counterparts, which include high installation costs (cabling)and lack of patient mobility. The main difference betweenpresented...