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Wyniki wyszukiwania dla: AEROBIC BIOLOGICAL
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Monitoring and efficiency assessment of biofilter air deodorization using electronic nose prototype
PublikacjaBiofiltration is one of the techniques used to reduce odorants in the air. It is based on the aerobic degradation of pollutants by microorganisms located in the filter bed. The research presents the possibility of using the electronic nose prototype for monitoring and efficiency assessment of air biofiltration. The study was conducted using model gas mixtures containing representatives of three groups of chemical compounds: n-hexane...
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Use of Escherichia coli Nissle 1917 producing recombinant colicins for treatment of IBD patients
PublikacjaPatients with Crohn’s Disease and ulcerative colitis infected with Adherent-Invasive Escherichia coli strains constitute the largest group among Inflammatory Bowel Disease subjects, when taking into account all known etiological agents of the disease. A possible link between these pathogenic bacteria and inflammation process has gained the confidence in recently published papers. Observed enteric neuroglial cells apoptosis and...
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Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
PublikacjaElectrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...
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Evidence for attenuated cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine removal in cancer patients
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Linking the diversity of native flora to land cover heterogeneity and plant invasions in a river valley
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Power-line corridors as source habitat for butterflies in forest landscapes
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Numerical and behavioral responses of waterfowl to the invasive American mink: A conservation paradox
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The role of churches in maintaining bird diversity: A case study from southern Poland
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Evaluating conservation tools in Polish grasslands: The occurrence of birds in relation to agri-environment schemes and Natura 2000 areas
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Expansion and population dynamics of a non-native invasive species: the 40-year history of American mink colonisation of Poland
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Effect of silver nanoparticles on human primary keratinocytes
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Callus of American ginseng (Panax quinquefolius) as a source of ginsenosides – medicinal secondary metabolites
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Cognitive costs of reproduction: life‐history trade‐offs explain cognitive decline during pregnancy in women
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Higher luteal progesterone is associated with low levels of premenstrual aggressive behavior and fatigue
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Mild poikilocapnic hypoxia increases very low frequency haemoglobin oxygenation oscillations in prefrontal cortex
PublikacjaBackground: The aim of the study was to investigate the effect of mild cerebral hypoxia on haemoglobin oxygenation(HbO2), cerebrospinal fluid dynamics and cardiovascular physiology. To achieve this goal, four signals were recorded simultaneously: blood pressure, heart rate / electrocardiogram, HbO2 from right hemisphere and changes of subarachnoid space (SAS) width from left hemisphere. Signals were registered from 30 healthy,...
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Peptydy penetrujące – rodzaje i mechanizmy przenikania przez błony komórkowe
PublikacjaPeptydy penetrujące z pewnością są wyjątkową i ciekawą grupą związków peptydowych. Zostały odkryte ponad dwadzieścia lat temu, ale wiedza na ich temat wciąż jest rozbudowywana. Liczne badania nad mechanizmami ich przenikania do wnętrza komórek pozwalają zrozumieć jakie cechy strukturalne warunkują ich zdolność do penetracji komórek. Wiedza ta pozwala na projektowanie nowych, bardziej efektywnych peptydów penetrujących., które mogą...
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Badanie i porównanie zdolności wybranych leków i związków przeciwnowotworowych do międzyłańcuchowego sieciowania DNA mitochondrialnego i jądrowego w komórkach nowotworowych
PublikacjaCelem pracy było zbadanie zdolności przeciwnowotworowych związków do indukowania międzyłańcuchowych wiązań sieciujących DNA mitochondrialne w ludzkich komórkach nowotworowych oraz porównanie ze zdolnością do sieciowania DNA jądrowego. Pochodna 4-metylo-1-nitroakrydyny C-1748, Ledakrin i mitomycyna C wykazują zdolność do sieciowania mtDNA i jDNA w komórkach raka okrężnicy HCT-8 w sposób zależny od dawki; C-1748 w komórkach raka...
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A new approach to designing control of dissolved oxygen and aeration system in sequencing batch reactor by applied backstepping control algorithm
PublikacjaThe Wastewater Treatment Plant (WWTP) is a very complex system, due to its nonlinearity, time-variance, and multiple time scales in its dynamics among others. The most important control parameter in a WWTP is the Dissolved Oxygen (DO) concentration. The tracking problem of the DO concentration is one of the most fundamental issues in biological wastewater treatment. Proper DO concentration control is necessary to achieve adequate...
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Tuftsin-Properties and Analogs
PublikacjaImmunomodulation is one of the significant therapeutic strategies. It includes both stimulation or suppression of the immune system by a variety of substances called immunomodulators, designed to regulate the immune response of the organism to infections of varying etiology. An example of such a substance is tuftsin (TKPA) 3 (Fig. (1)). Tuftsin is an endogenous immunomodulator of a wide spectrum of biological activity. Tetrapeptide...
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Environmental Tobacco Smoke: Exposure, Health Effects, and Analysis
PublikacjaTobacco smoke contains more than 4,000 chemicals, and 44 compoundshave been classified as human carcinogens. Toxicity can beboth mainstream smoke as well as the constituents of environmentaltobacco smoke. In the light of this evidence, work is intensifyingon assessing exposure on the basis of the results of tests performedto quantify the amounts of suitable environmental tobacco smokeconstituent biomarkers in samples of biological...
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Tuning of food wastes bioavailability as feedstock for bio-conversion processes by acoustic cavitation and SPC, SPS, or H2O2 as external oxidants
PublikacjaThe growing amount of food wastes makes them a suitable source for the generation of bioproducts through anaerobic digestion. Appropriate hydrolysis of the feedstock can enhance the efficiency of production of desired products. In this work, acoustic cavitation (AC) was employed as a pretreatment method to enhance hydrolysis stage by the modification of model (potato-based) food waste for increase in soluble chemical oxygen demand...
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Synthesis of the inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors
PublikacjaIn this review are summrized newly described IMPDH inhibitors. The article concerns both synthetic pathways and biological activities of the most promising compounds.
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Types of Treatment Wetlands
PublikacjaThe removal of pollutants in treatment wetland systems is the result of the sorption of biochemical pollutants, redox reactions, and a biological activity of microorganisms as well as hydrophytes plants.
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Methods of ZnO nanoparticles synthesis
PublikacjaZinc oxide nanostructures are interesting nanomaterials with a wide range of applications. Since the physical and chemical properties of ZnO nanoparticles are influenced both by their shape and size, a control of morphology of ZnO structures is needed for their commercial usage. Different chemical, physical, and biological methods used to produce ZnO nanostructures can be found in the literature. The production of ZnO nanoparticles...
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Denitrifcation rate in the mainstream deammonification
PublikacjaThe conventional processes of biological nitrogen removal based on nitrification and denitrification does not fit properly into the concept of the circular economy. As the alternative one should consider the deammonification process, which is a combination of partial nitrification (nitritation) and Anammox processes. It consists of removing ammonium nitrogen from wastewater under anaerobic conditions by a group of autotrophic microorganisms....
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Oxylipin profiling for clinical research: Current status and future perspectives
PublikacjaOxylipins are potent lipid mediators with increasing interest in clinical research. They are usually measured in systemic circulation and can provide a wealth of information regarding key biological processes such as inflammation, vascular tone, or blood coagulation. Although procedures still require harmonization to generate comparable oxylipin datasets, performing comprehensive profiling of circulating oxylipins in large studies...
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The characterization of collagen‑based scaffolds modified with phenolic acids for tissue engineering application
PublikacjaThe aim of the experiment was to study the morphology of collagen-based scaffolds modified by caffeic acid, ferulic acid, and gallic acid, their swelling, and degradation rate, as well as the biological properties of scaffolds, such as antioxidant activity, hemo- and cytocompatibility, histological observation, and antibacterial properties. Scaffolds based on collagen with phenolic acid showed higher swelling rate and enzymatic...
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Cavitation-based technologies for pretreatment and processing of food wastes: Major applications and mechanisms – A review
PublikacjaConversion of food wastes to valuable products is an important topic for sustainable development. Feedstock hydrolysis is a stage strongly affecting the anaerobic digestion process, and resistance of food waste towards hydrolysis causes a decrease in product yield. Such as biomethane, biohydrogen, biohythane, VFAs, and lactic acids. Moreover, mass transfer is a serious limitation of transesterification for the production of biodiesel....
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Diamond-based protective layer for optical biosensors
PublikacjaOptical biosensors have become a powerful alternative to the conventional ways of measurement owing to their great properties, such as high sensitivity, high dynamic range, cost effectiveness and small size. Choice of an optical biosensor's materials is an important factor and impacts the quality of the obtained spectra. Examined biological objects are placed on a cover layer which may react with samples in a chemical, biological...
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Biomechanical properties of 3D-printed bone models
PublikacjaBone lesions resulting from large traumas or cancer resections can be successfully treated by directly using synthetic materials or in combination with tissue engineering methods (hybrid). Synthetic or hybrid materials combined with bone tissue’s natural ability for regeneration and biological adaptation to the directions of loading, allow for full recovery of its biological functions. Increasing interest in new production methods...
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Biotrickling filtration of n-butanol vapors: process monitoring using electronic nose and artificial neural network
PublikacjaBiotrickling filtration is one of the techniques used to reduce odorants in the air. It is based on the aerobic degradation of pollutants by microorganisms located in the filter bed. The research presents the possibility of using the electronic nose prototype combined with artificial neural network for biofiltration process monitoring in terms of reduction in n-butanol concentration and odour intensity of treated air. The study...
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Therapeutic Potential of Multifunctional Tacrine Analogues
PublikacjaTacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease. The interest in these compounds is mainly related to a high variety of their structure and biological properties. In the present review, we...
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Seaweed utilization issues in biogas production
PublikacjaMacroalgae can be seen as a renewable feedstock for the production of biofuels in many coastal areas around the World and especially in Baltic Sea region where the eutrophication is particularly troublesome. The investigation of anaerobic digestion technologies for extracting inexhaustible bioenergy from seaweed was conducted in many research institutions mainly in laboratory scale. Although seaweeds seem to have a great potential...
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Pre-analytical aspects in metabolomics of human biofluids – sample collection, handling, transport, and storage
PublikacjaMetabolomics is the field of omics research that offers valuable insights into the complex composition of biological samples. It has found wide application in clinical diagnostics, disease investigation, therapy prediction, monitoring of treatment efficiency, drug discovery, or in-depth analysis of sample composition. A suitable study design constitutes the fundamental requirements to ensure robust and reliable results from the...
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A new finite element with variable Young's modulus
PublikacjaThe Finite Element Method (FEM) is a numerical technique that is well-established in the field of engineering. However, in biological sciences, it is justtaking its first steps. Bone tissue is an example of biological material which isexposed to high loads in its natural environment. Practically every movementof the body results in changing stress levels in the bone. Nature copes with thisvery well but when human intervention is...
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Intelligence Augmentation and Amplification: Approaches, Tools, and Case Studies
PublikacjaMost experts agree that truly intelligent artificial system is yet to be developed. The main issue that still remains a challenge is imposing trust and explainability into such systems. However, is full replication of human intelligence really desirable key aim in intelligence related technology and research? This is where the concept of augmented intelligence comes into play. It is an alternative conceptualization of artificial...
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Green aspects, developments and perspectives of liquid phase microextraction techniques
PublikacjaDetermination of analytes at trace levels in complex samples (e.g. biological or contaminated water or soils) are often required for the environmental assessment and monitoring as well as for scientific research in the field of environmental pollution. A limited number of analytical techniques are sensitive enough for the direct determination of trace components in samples and, because of that, a preliminary step of the analyte...
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A selection of the optimal eluent components for separation of carnivorous plants metabolites by planar chromatography chromatography
PublikacjaAbstract: The development of the new procedures of the separation components with the complicated chemical structure from natural complex matrix by column chromatography is very difficult and in many cases expensive. Therefore to pre-select the conditions of the separation process the use of thin layer chromatography (TLC) is proffered. The possibility of proceeding the chromatographic process for several mixtures on single plate,...
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Particle size analysis of suspensions in removing of organic matter and phosphorus from waste water and surface water
PublikacjaIn this paper the particle size of suspended solids in the removing of organic matter and phosphorus compounds from lake- and waste- water treated in the Ecological Treatment Systems (ETS) was analyzed.The invesigated materials were taken from two ETS located in Pomerania Region/Poland. Object in Swarzewo is 3rd stage of biological treatment of municipal waste water, while object in Kartuzy has task to remove a phosphorus from...
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Preliminary Testing of the Influence of Modified Polycaprolactones on Anabaena Variabilis Growth in Seawater
PublikacjaSeveral new biodegradable polymer materials have recently come onto the global market. Mostly the results on degradation kinetic studies are presented. This paper suggests using one of the tests to estimate the impact of polymer packaging material on sea life. The microorganism chosen was Anabaena variabilis (identified in many waters, including those of the Baltic Sea, especially in the Gulf of Gdansk and Puck Bay; this cyanobacterium...
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PARTICLE SIZE ANALYSIS OF SUSPENSIONS IN REMOVING OF ORGANIC MATTER AND PHOSPHORUS FROM WASTEWATER AND SURFACE WATER
PublikacjaIn this paper the particle size of suspended solids in the removing of organic matter and phosphorus compounds from lake water and wastewater treated in the Ecological Treatment Systems (ETS) was analyzed. The invesigated materials were taken from two ETS located in Pomerania Region/Poland. Object in Swarzewo is 3rd stage of biological treatment of municipal wastewater, while object in Kartuzy has task to remove a phosphorus from...
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Study of the anticancer potential of Cd complexes of selenazoyl-hydrazones and their sulfur isosters
PublikacjaThe biological activity of Cd compounds has been investigated scarce since Cd has been recognized as a human carcinogen. However, the toxicity of cadmium is comparable to the toxicity of noble metals such as Pt and Pd. The paradigm of metal toxicity has been challenged suggesting that metal toxicity is not a constant property, yet it depends on many factors like the presence of appropriate ligands. Studies on anticancer activity...
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Wpływ ciągłego i naprzemiennego napowietrzania na efektywność usuwania amoniaku z wód osadowych w procesie nitrytacja-ANAMMOX
PublikacjaOkreślenie wpływu ciągłego i naprzemiennego napowietrzania, a także stężenie rozpuszczonego tlenu na tempo procesu beztlenowego utleniania amoniaku. Badania oparte zostały o dwa systemy napowietrzania „niemiecki” stosowany przez Jardina i Hennerkesa (2012), który polegał na wprowadzeniu krótkich naprzemiennych faz napowietrzania i mieszania oraz system „szwajcarski” opisany przez Jossa i wsp. (2009, 2011) w którym reaktor...
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Distinct cellular uptake patterns of two anticancer unsymmetrical bisacridines and their metabolic transformation in tumor cells.
PublikacjaUnsymmetrical bisacridines (UAs) represent a novel class of anticancer agents. Their high cytotoxicity towards multiple human cancer cell lines and inhibition of human tumor xenograft growth in nude mice signal their potential for cancer treatment. Therefore, the mechanism of their strong biological activity is broadly investigated. Here, we explore the efflux and metabolism of UAs, as both strongly contribute to the development...
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Bioactive quaternary ammonium ionic liquids.
PublikacjaAn ionic liquid (IL) is an organic compound that contains at least one ionic bond. It consists of an organic cation and an organic or inorganic anion. It is an organic salt having a melting point below 100C. A very interesting group of IL are those with a long chain quaternary ammonium cation. They are formed by direct synthesis or by an anion-exchange reaction in quaternary ammonium halides. Popular and cheap precursors for the...
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Optoelectronic investigation of nanodiamond interactions with human blood
PublikacjaWe present optoelectronic investigation of in vitro interactions of whole human blood with different nanodiamond biomarkers. Plasmo-chemical modifications of detonation nanodiamond particles gives the possibility for controlling their surface for biological applications. Optical investigations reveal the biological activity of nanodiamonds in blood dependent on its surface termination. We compare different types of nanodiamonds:...
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Impact of temperature on optical sensing in biology based on investigation of SARS‐CoV ‐2
PublikacjaIn this paper, we present an investigation of the influence of the temperature on the sensing of biological samples. We used biofunctionalized microsphere-based fiber-optic sensor to detect immunoglobulin G attached to the sensor head at temperatures relevant in biological research: 5°C, 25°C, and 55°C. The construction of the sensor allowed us to perform measurements in the small amount of solution. The results of our experiment...
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The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
PublikacjaThe term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical,...
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Effects of the Origin and Deacetylation Degree of Chitosan on Properties of Its Coatings on Titanium
PublikacjaThe properties of chitosan coatings on titanium surfaces may be influenced by a variety of factors, including their chemical characteristics and the deposition method. The aim of this research was to determine the influence of a chitosan’s origin (a type of shrimp) and deacetylation degree (DD), when deposited on a very smooth titanium surface, on adhesion and biological behavior. The tests were performed using chitosan of a degree...
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Requirements, modifications and methods of mechanical testing of bone cement – literature review
PublikacjaThe Aim of the paper is to show the basic requirements for the bone cement, its modifications in terms of physical, mechanical and biological properties and testing methods. This publication is intended to be a source of systematized basic knowledge regarding the modified bone cement.