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Wyniki wyszukiwania dla: BIOGENIC AMINES
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublikacjaIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...
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Numerical analysis of vacuum drying of a porous body in the integrated domain
Publikacjan the present study, the vacuum drying process of an apple slice is numerically modeled based on a control volume method. Transient two-dimensional Navier– Stokes, energy, moisture, and Luikov equations are solved by numerical coding (Fortran) to simulate the simultaneous heat and mass transfer in the ambient and apple slice, respectively. The privilege of using Luikov's model is that the capillary forces are considered, and a...
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Biochemical, Structural Analysis, and Docking Studies of Spiropyrazoline Derivatives
PublikacjaIn this study, we evaluated the antiproliferative potential, DNA damage, crystal struc‐ tures, and docking calculation of two spiropyrazoline derivatives. The main focus of the research was to evaluate the antiproliferative potential of synthesized compounds towards eight cancer cell lines. Compound I demonstrated promising antiproliferative properties, especially toward the HL60 cell line, for which IC50 was equal to 9.4 μM/L....
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New Screening Protocol for Effective Green Solvents Selection of Benzamide, Salicylamide and Ethenzamide
PublikacjaNew protocol for screening efficient and environmentally friendly solvents was proposed and experimentally verified. The guidance for solvent selection comes from computed solubility via COSMO-RS approach. Furthermore, solute-solvent affinities computed using advanced quantum chemistry level were used as a rationale for observed solvents ranking. The screening protocol pointed out that 4-formylomorpholine (4FM) is an attractive...
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MODELOWA GOSPODARKA OSADOWA W OCZYSZCZALNI ŚCIEKÓW ZORIENTOWANA NA ZWIĘKSZENIE PRODUKCJI ENERGII ODNAWIALNEJ I ODZYSK ZWIĄZKÓW BIOGENNYCH
PublikacjaOczyszczalnie ścieków poddawane są stopniowej zmianie paradygmatów. Początkowo kładziono nacisk na cel podstawowy – oczyszczanie ścieków i zwiększenie wymagań w stosunku do jakości ścieków oczyszczonych odprowadzanych do odbiorników. Poprawa efektywności energetycznej aż po uzyskanie samowystarczalności energetycznej stanowiła kolejny trend budzący zainteresowanie ze względu na korzyści ekonomiczne wynikające z oszczędności w zakupie...
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Applying Web 2.0 Concepts to Creating Energy Planning Portal
PublikacjaCommunity authorities in Europe are tasked to create Advanced Local Energy Plans (ALEP), which encompasses collecting local data on current energy use and generation, as well as generating future development scenarios. Both the data and the development scenarios must be publicly accessible as a basis for energy-related decisions taken by residents, local companies and other local institutions. The data must partially be collected...
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Applying agiile practices to the development of safety-critical software
PublikacjaDevelopment of safety critical software is subjected to numerous restrictions and recommendations. To meet these requirements classical software development models (e.g. V-model) are usually applied. Agile methodologies, although rapidly increasing their popularity, were generally regarded as unsuitable for such projects. However, they offer potential benefits which provide a strong incentive to incorporate them into safety-critical...
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Valuation of architectural heritage by multicultural student groups
PublikacjaIn this article, the author addresses the education of architecture students in the field of architectural history and the determination of the value of architectural objects. Important changes at present are underway concerning this. Both the role of architectural history in architectural education and content in architectural history curricula is changing. The need for re-evaluation...
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Examining Ownership Equity as a Psychological Factor on Tourism Business Failure Forecasting
PublikacjaThis paper examines ownership equity as a predictor of future business failure within the tourism and hospitality sectors. The main goals of this study were to examine which ratios are the most important for a tourism business failure forecasting model and how significant is the “total percentage of equity ownership by company directors” ratio compared with other ratios associated with the probability of bankruptcy. A stepwise...
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Alternative cogeneration thermodynamic cycles for domestic ORC
PublikacjaThe Organic Flash Cycle (OFC) is suggested as a vapor power cycle that could potentially improve the efficiency of utilization of the heat source. Low and medium temperature finite thermal sources are considered in the cycle. Additionally the OFC’s aim is to reduce temperature difference during heat addition. The study examines 2 different fluids. Comparisons are drawn between the OFC and an optimized basic Organic Rankine Cycle...
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Georg Simmel’s The Philosophy of Money and the Modernization Paradigm
PublikacjaThis article examines Georg Simmel’s contribution to the understanding of how money functions in modern society, mainly scrutinizing his most important work on that topic, The Philosophy of Money, in the context of modernization theories. Modernization theories, as developed (most notably) by Marx, Weber, Durkheim, and Elias, attempted to explain the transition from feudalism and a closed agrarian economy to capitalism and industrial...
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Possible effects of the 1984 St. Clair River ice jam on bed changes
PublikacjaThis study examines the possible effect of the record ice jam of 1984 in the St. Clair River on river bed changes and conveyance. Numerical simulations were made to examine the flow and bed shear stresses during the jam formation and release periods. Simulation results indicate that the ice jam in the river did not cause a significant increase in bed shear stress compared to pre- and post-jam open water conditions. The insignificant...
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Hedging Strategies of Derivatives Instruments for Commodity Trading Entities
PublikacjaHedging as an outcome of risk management arises to account several questions. Mentioned aspect of size of the hedging is one of them. Latter questioning refers to whether producer of manufacturer are willing to secure entire exposure, when the hedging should start, now or later in the future, what is the vision on market like direction of market, time of interest, magnitude of exposure, what would be the preferred instruments of...
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Semi-definite programming and quantum information
PublikacjaThis paper presents a comprehensive exploration of semi-definite programming (SDP) techniques within the context of quantum information. It examines the mathematical foundations of convex optimization, duality, and SDP formulations, providing a solid theoretical framework for addressing optimization challenges in quantum systems. By leveraging these tools, researchers and practitioners can characterize classical and quantum correlations,...
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Landscape, EIA and decision-making. A case study of the Vistula Spit Canal, Poland
PublikacjaAlthough landscapes are often considered public goods, they frequently receive inadequate attention in Environmental Impact Assessments (EIAs), particularly in Poland. This neglect often leads to visible degradation during investment processes. This article examines the case of the Vistula Spit Canal, currently the largest engineering project under construction in Poland. We analysed whether the conclusions drawn in the EIA report,...
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Digitalization and digital skills development patterns. Evidence for European countries
PublikacjaThis chapter contextualizes the digitalization process and the digital skills concept. It discusses the very process of technology diffusion, emphasizing several unique features of digital technologies that make them globally available. Next, it turns to the digital skills concept, clarifying how and why they reshape the societal and economic landscape. It also briefly addresses the digital divide and skill-biased technological...
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Novel Diazocrowns with Pyrrole Residue as Lead(II) Colorimetric Probes
PublikacjaNovel 18- and 23-membered diazomacrocycles were obtained with satisfactory yields by diazocoupling of aromatic diamines with pyrrole in reactions carried under high dilution conditions. X-ray structure of macrocycle bearing five carbon atoms linkage was determined and described. Compounds were characterized as chromogenic heavy metal ions receptors. Selective color and spectral response for lead(II) was found in acetonitrile and...
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A Measurement-Based Approach for Speed Control of Induction Machines
PublikacjaThis paper presents an approach to design a measurement-based controller for induction machines. The proposed control approach is motivated by the fact that developing an appropriate mechanical model of such induction machines is a challenging task. Since our proposed control methodology is only on the basis of measured data, the controller design does not require any information about the model of the mechanical part. The control...
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Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase
PublikacjaCentra aktywne izomerazy fosfoglukozowej (PGI) oraz domeny izomerazowej (HPI) syntazy glukozamino-6-fosforanu (GlcN-6-P), wykazują podobieństwo ułożenia przestrzennego kluczowych reszt aminokwasowych, z wyjątkiem reszty Arg272 PGI i reszt Lys603 i Lys485 HPI. Dziesięć pochodnych D-heksitolo-6-P, kwasu 5-fosfoarabonowego i kwasu 6-fosfoglukonowego, strukturalnych analogów cis-enolaminy lub cis-enolanu, przypuszczalnych stanów przejściowych...
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Selected organophosphorus compounds with biological activity. Applications in medicine
PublikacjaThe purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...
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The Finite Elements Method application to assesment the impact of turbulence generated by wind turbines on their lacation inclose proximity of overhead high voltage power transmissionlines
PublikacjaThe paper presents selected aspects of construction of wind turbines location concerning aerodynamic impact on power lines. Reaserch is based on the source data concerning the aerodynamic impact of a wind farm consisting of 8 turbines and 400 kV power line, an analysis of the possibility of wind farm locating in the immediate vicinity of the line was carried out. There are serious problems with locating higher capacity wind farms...
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Convenient Synthesis of Functionalized Unsymmetrical Vinyl Disulfides and Their Inverse Electron-Demand Hetero-Diels-Alder Reaction
PublikacjaThe simple, convenient, and efficient methods for the preparation of unsymmetrical vinyl disulfides with additional functional groups under mild conditions with moderate to high yields were designed. The developed methods include the reaction of S-vinyl phosphorodithioate with thiotosylates or S-vinyl thiotosylate with thiols. The designed methods allow for the synthesis of unsymmetrical vinyl disulfides with additional functionalities...
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Discussing daylight simulations in a proposal for online daylighting education.
PublikacjaThere is increasing interest concerning daylighting in the building sector. However, such knowledge is difficult to penetrate the curricula of architects and designers as existing educational programmes often do not provide sufficient training on BPS. This also leads to superficial use of daylight simulations. This paper presents a proposal for a needs-based education package on daylighting design, that mixes modular eLearning...
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Flame retardant epoxy/halloysite nanotubes nanocomposite coatings: Exploring low-concentration threshold for flammability compared to expandable graphite as superior fire retardant
PublikacjaEpoxy nanocomposites containing halloysite nanotubes (HNTs) were developed and their low-concentration thresholds for thermal stability and flame retardancy were compared with that of epoxy system containing expandable graphite (EG), as a reference with superior flame retardancy. The effects of HNTs and EG on the peak of Heat Release Rate (pHRR), Total Heat Release (THR), and Time-To-Ignition (TTI) of the prepared samples were...
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The influence of different glycerine purities on chemical recycling process of polyurethane waste and resulting semi‐products
PublikacjaChemical recycling is the most favourable recycling method due to the possibility of polyol recovery. This work is dedicatedto the utilisation of crude glycerine and polyurethane waste. It aims at determining the impact of the use of glycerine fromthe production of biodiesel with various degrees of purity as a cleavage agent on the decomposition process of polyurethanefoam. The influence of glycerine purit y on the chemical structure...
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Application of safirinium N-hydroxysuccinimide esters to derivatization of peptides for high-resolution mass spectrometry, tandem mass spectrometry, and fluorescent labeling of bacterial cells
PublikacjaMass spectrometry methods are commonly used in the identification of peptides and biomarkers. Due to a relatively low abundance of proteins in biological samples, there is a need for the development of novel derivatization methods that would improve MS detection limits. Hence, novel fluorescent N-hydroxysuccinimide esters of dihydro-[1,2,4]triazolo[4,3-a]pyridin-2-ium carboxylates (Safirinium P dyes) have been synthesized. The...
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Przejazdy kolejowe na modernizowanych i rewitalizowanych liniach kolejowych - przepisy a rzeczywistość
PublikacjaPrzy modernizacji i rewitalizacji dróg szynowych jednym z elementów infrastruktury, wymagającym szczególnej uwagi już na etapie planowania inwestycji, są przejazdy i przejścia w poziomie szyn. Obowiązujące przepisy krajowe pochodzą z lat 90. ubiegłego wieku i w wielu aspektach nie uwzględniają specyfiki najczęściej obecnie występujących na liniach kolejowych inwestycji modernizacyjnych i rewitalizacyjnych. W przypadku linii należących...
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Humanizacja traktu porodowego
PublikacjaPowszechny w latach 80-tych XX wieku zmedykalizowany model porodu podlega stopniowej humanizacji. Artykuł omawia współczesne tendencje w podejściu do porodu i ich wpływ na układ funkcjonalno-przestrzenny traktu porodowego. Przedstawia najważniejsze wymagania stawiane obecnie traktom porodowym. Na podstawie przykładów rozwiązań realizacyjnych i projektowych analizuje problematykę modernizacji zespołów porodowych w Polsce.
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Designing drainage systems – possible application of advanced calculations and hydrodynamical modeling
PublikacjaNowadays we can observe a faster development of drainage systems than ever. This gives us an opportunity to de- sign more efficient systems that can cope with the rapid growth of cities and, what comes with it, impervious surfaces. Here the question arises, whether traditional methods used in drainage system design are potent enough to cope with the emerging prob- lems and difficulties. In this paper we will make...
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Measurements of ASON/GMPLS connection control layer performance according to the ETSI methodology
PublikacjaMeasurements of performance have always been crucial for evaluation of telecommunication systems, especially for implementation of network control elements responsible for connection handling which regards to bandwidth reservation, modification and release. That problem also arises in Automatically Switched Optical Network/Generalized Multiprotocol Label Switching (ASON/GMLPS) architecture, which is considered as one of the components...
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Dynamics of productivity in higher education: cross-european evidence based on bootstrapped Malmquist indices
PublikacjaAbstract This study examines patterns of productivitychange in a large set of 266 public higher educationinstitutions (HEIs) in 7 European countries across the timeperiod 2001-2005. We adopt consistent bootstrap estimationprocedures to obtain confidence intervals for Malmquistindices of HEI productivity and their components.Consequently, we are able to assess the statistical significanceof changes in HEI productivity, efficiency...
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Do new EU members have any chance of earning as much as Westerns do?
PublikacjaThis article examines the wage dispersion in the European Union in the last ten years (1996-2006). The research is motivated by the fact that New Members States (NMS) expected that wage convergence would occurred after their accession to the EU. At the same time Old Member States (OMS) have been increasingly concerned with the possibility that the EU enlargement could influence their local labor markets and wages through new channels...
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Tuning matrix-vector multiplication on GPU
PublikacjaA matrix times vector multiplication (matvec) is a cornerstone operation in iterative methods of solving large sparse systems of equations such as the conjugate gradients method (cg), the minimal residual method (minres), the generalized residual method (gmres) and exerts an influence on overall performance of those methods. An implementation of matvec is particularly demanding when one executes computations on a GPU (Graphics...
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Influence of external climate on natural ventilation performance in buildings
PublikacjaNatural ventilation is driven by either buoyancy forces or wind pressure forces or their combinations that inherit stochastic variation into ventilation rates [ CITATION Hun99 \l 1045 ]. We now that these factors have influence on air flow speed and thermal comfort inside building. This work examines the relationship between external climate and natural ventilation including thermal comfort. The work tries in the first instance...
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Dirac fermions and possible weak antilocalization in LaCuSb2
PublikacjaLayered heavy-metal square-lattice compounds have recently emerged as potential Dirac fermion materials due to bonding within those sublattices. We report quantum transport and spectroscopic data on the layered Sb square-lattice material LaCuSb2. Linearly dispersing band crossings, necessary to generate Dirac fermions, are experimentally observed in the electronic band structure observed using angle-resolved photoemission spectroscopy,...
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English, French, and Polish Aliases of Criminals: Diversity of Inspirations in their Creation and Typical Nicknaming Schemes
PublikacjaThe present paper examines the topic of aliases of criminals, which seems to be understudied in linguistic research. Therefore, this article’s primary goal is to describe how criminals’ aliases are created and what are the differences and similarities in that process in English, French, and Polish. Firstly, the theoretical background concerning the topic of pseudonyms is presented. Then, the corpus gathered for this paper (available...
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Continuum wave functions for estimating the electric dipole moment: Calculation based on a multiconfiguration Dirac-Hartree-Fock approximation
PublikacjaThe multiconfiguration Dirac-Hartree-Fock method is employed to calculate the continuum electron wave functions, which are then used to estimate their contribution to the atomic electric dipole moment (EDM) of 129Xe. The EDM arises from (P,T)-odd electron-nucleon tensor-pseudotensor and pseudoscalar-scalar interactions, the nuclear Schiff moment, the interaction of the electron electric dipole moment with nuclear magnetic moments,...
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Theological Intersections: Newman’s ‘Primacy of God’ in Modern Church Discourse
PublikacjaThis article critically examines the Catholic–Anglican theological dialogue, centering on John Henry Newman’s ‘Primacy of God’, Catholic synodality, and Anglican comprehensiveness. It illuminates the interconnectedness of these elements, revealing their potential to enhance ecumenical conversations. Newman’s concept of communal faith and divine primacy resonates across both traditions, advocating a transformative,...
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Impact of Geometrical Imperfections on Estimation of Buckling and Limit Loads in a Silo Segment Using the Vibration Correlation Technique
PublikacjaThe paper examines effectiveness of the vibration correlation technique which allows determining the buckling or limit loads by means of measured natural frequencies of structures. A steel silo segment with a corrugated wall, stiffened with cold-formed channel section columns was analysed. The investigations included numerical analyses of: linear buckling, dynamic eigenvalue and geometrically static non-linear problems. Both perfect...
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Bridging the Gap Between Legitimacy and Neutralisation Strategies in Sustainability Reporting
PublikacjaAmid global sustainability challenges, such as climate change, companies operating in different industries face increasing demands for accountability and transparency. To meet these demands, sustainability reporting (SR) has become a mainstream business practice in communicating companies’ positive and negative sustainability impacts. This short paper aims to increase our understanding of how companies may release negative information...
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Market Regeneration in Line with Sustainable Urban Development
PublikacjaThis article presents the study of the optimal design solutions for regeneration of marketplaces. It examines the design variants for the revitalisation of the marketplace, in particular, investment in their modernisation in order to find the most optimal model for transforming these public spaces to have a significant impact on the city’s development. The research is a comparative analysis of the implementation of regeneration...
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Finite Element Approaches to Model Electromechanical, Periodic Beams
PublikacjaPeriodic structures have some interesting properties, of which the most evident is the presence of band gaps in their frequency spectra. Nowadays, modern technology allows to design dedicated structures of specific features. From the literature arises that it is possible to construct active periodic structures of desired dynamic properties. It can be considered that this may extend the scope of application of such structures. Therefore,...
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Trade differentiation and the characteristics of new imported and exported products - international panel data analysis
PublikacjaDrawing on o large panel of international economies we have shown how the set of imported and exported products evolves in economic growth process. Strong activity at the extensive margin, manifested through the rise in the number of active export and import lines, is typical for early stages of development. Trade diversification tendency, typical for a predominant mass of observations in our panel, is associated with changes in...
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Design of Microwave Lossy Filter Based on Substrate Integrated Waveguide (SIW)
PublikacjaIn this letter, we propose a lossy three-pole Chebyshev filter centered at 5.15 GHz, based on the substrate integrated waveguide (SIW) with scattering characteristics shifted down by 5.68 dB. The filter is composed of three directly coupled SIW cavities with three lossy couplings between nonadjacent resonators. These additional couplings are realized using mixed coupled slot and microstrip lines connected with metal electrode leadless...
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Time-frequency analysis of acoustic signals using concentrated spectrogram
PublikacjaThe paper presents improved method of time-frequency (TF) analysis of discrete-time signals. The method involves signal's local group delay (LGD) and channelized instantaneous frequency (CIF) to purposely redistribute all Short-time Fourier transform (STFT) lines. Additionally, the energy concentration index (ECI) and some histogram-like statistics are used to evaluate readability of estimated TF distributions of the energy. Recorded...
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Chinese Law Research Guide
PublikacjaA journey of a thousand miles begins with a single step. This Research Guide will be the first step in your journey with Chinese law. China grows more important every day from a global perspective. However, studying and conducting research on Chinese law can be extremely challenging, especially if you do not know Mandarin well. This book is intended as a compact but comprehensive research guide that would provide students (especially...
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Testing A Novel Gesture-Based Mixing Interface
PublikacjaWith a digital audio workstation, in contrast to the traditional mouse-keyboard computer interface, hand gestures can be used to mix audio with eyes closed. Mixing with a visual representation of audio parameters during experiments led to broadening the panorama and a more intensive use of shelving equalizers. Listening tests proved that the use of hand gestures produces mixes that are aesthetically as good as those obtained using...
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Remote current measurement with FPGA digital processing
PublikacjaThe work presents an implementation of a modular measurement and control systemthat controls variants of mains supply of 230V electrical equipment. The system allowsto supervise power consumption in the office electronic equipment. The system detectsthe instant of the reduced power consumption by a device and makes possible itsswitch-off in order to reduce energy cost. The current is measured with integratedcurrent/voltage converters....
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Excited-state proton transfer and geminate recombination in the molecular cage of β-cyclodextrin
PublikacjaExcited-state proton transfer and geminate recombination in aqueous heptakis(2,6-di-O-methyl)-β-cyclodextrin have been compared with those in water by monitoring the photoinduced prototropic tautomerization of 6-hydroxyquinoline, which occurs via forming anionic intermediate. Enol deprotonation decelerates by 18 times whereas its reverse process accelerates slightly with encapsulation. The imine protonation of the intermediate...
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Niebiałkowe związki azotowe. Rozdział 8
PublikacjaAzot związków niebiałkowych stanowi od kilku do kilkudziesięciu procent ogólnej ilości azotu w różnych surowcach żywnościowych. Wskutek enzymatycznych i chemicznych przemian w czasie przechowywania i przetwarzania zmienia się udział i skład tych związków. Niebiałkowe związki azotowe uczestniczą w tworzeniu zapachu i smaku produktów żywnościowych, niektóre z nich, np. histamina są szkodliwe dla zdrowia, inne np N-nitrozoaminy lub...