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Wyniki wyszukiwania dla: GENOME EDITING

  • Study on population dynamics for triple-linked food chain using a simulation-based approach

    Publikacja

    - Evolving Systems - Rok 2019

    The procedures based on simulation have become a feasible testing method that does not require investing valuable resources to create a concrete prototype, especially with the increasing computational power of computers. Thus, design changes can be adopted and design errors can be fixed before it is too late. Simulation turns to be a cheap, safe and often more acceptable from an ethical perspective. In our work we summarize the...

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  • Knowledge management in SMEs – selected issues.

    Publikacja

    - Rok 2014

    The success of a small or medium-size enterprise might be dependent on the way in which this company manages its knowledge. With limited access to other resources like land, capital or labor force, the access to knowledge and its effective application might become a source of competitive advantage for an SME. It is confirmed that organizations, which successfully implement the concept of knowledge management might achieve better...

  • Physical and Thermophysical Properties of 1-Hexyl-1,4-diaza[2.2.2]bicyclooctanium Bis(trifluoromethylsulfonyl)imide Ionic Liquid

    Owing to their unique properties, ionic liquids (ILs) have become a real alternative to organic compounds. Nowadays, ILs are commonly used in a number of areas such as chemical synthesis and separation techniques. However, ionic liquids continue to have a limited applicability in industry because the information on their physical and chemical properties is not readily available. This paper presents, for the first time, the results...

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  • High temperature corrosion of evaporator tubes with thermal sprayed coatings

    Degradation examinations of outer surface of low-emission steam boiler evaporator tubes are presented in the paper. Metallographic evaluation of scale morphology, its micro sites chemical composition analysis and distribution of elements on cross sections have been performed. Water-wall tubes were exposed in steam boiler for up to two years period. Common tubes made of 16Mo3 steel suffered sulphide and molten salts corrosions....

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  • Bridging the Gap Between Legitimacy and Neutralisation Strategies in Sustainability Reporting

    Publikacja

    - Rok 2024

    Amid global sustainability challenges, such as climate change, companies operating in different industries face increasing demands for accountability and transparency. To meet these demands, sustainability reporting (SR) has become a mainstream business practice in communicating companies’ positive and negative sustainability impacts. This short paper aims to increase our understanding of how companies may release negative information...

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  • Targeting shelterin proteins for cancer therapy.

    Publikacja

    - DRUG DISCOVERY TODAY - Rok 2024

    As a global health challenge, cancer prompts continuous exploration for innovative therapies that are also based on new targets. One promising avenue is targeting the shelterin protein complex, a safeguard for telomeres crucial in preventing DNA damage. The role of shelterin in modulating ataxia- telangiectasia mutated (ATM) and ataxia-telangiectasia and Rad3-related (ATR) kinases, key players in the DNA damage response (DDR),...

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  • The Lost Kinetic Architecture and How to Reintroduce it in the Landscape – The Case Study of the Drainage Windmills in the Vistula Delta

    Recreating the lost kinetic landscape of the Vistula Delta is a considerable challenge. The study aims to propose a method for reproducing windmills and their effect on the landscape. The paper suggests a method based on the transposition of the forms of movement from windmills historically present in the region to modern forms. The method is based on a series of analyses starting with the study of the region and its history followed...

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  • AC-DC-DC Converter for Small Power Energy Storage Systems

    Publikacja

    - ENERGIES - Rok 2023

    The energy transformation driven by the development of renewable energy sources has become a reality for all power grid users. Prosumer energy, primarily utilizing photovoltaic installations, is one of the fastest-growing market segments. The advancement of technology, a decrease in electrochemical energy storage prices, and changes in the legal framework governing energy billing for grid-fed power have led to a growing interest...

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  • Preload monitoring in a bolted joint using Lamb wave energy

    The knowledge of the load in prestressed bolted connections is essential for the proper operation and safety of engineering structures. Recently, bolted joints have become an area of intensive research associated with non-destructive diagnostics, in particular in the context of wave propagation techniques. In this paper, a novel procedure of bolt load estimation based on the energy of Lamb wave signals was proposed. Experimental...

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  • HYDRODYNAMIC THRUST BEARINGS WITH POLYMER LINING

    Publikacja

    - TRIBOLOGIA - Rok 2016

    Polymeric linings of sliding surfaces of the hydrodynamic bearings have been used successfully for over 50 years. Despite of their long history of operation and research, they have not become wide spread in industrial applications. This fact may be surprising, considering th e conclusions that have been published concerning bearing operation and design. This paper summarizes the current...

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  • Balancing Energy Inputs/Outputs and GHG Emissions for Sustainable Wastewater Treatment – a Case Study

    Publikacja

    - Rok 2017

    The aim of the study is a model-based evaluation of the selected operating modes and technological upgrades on the energy balance and greenhouse gas (GHG) emissions in a large wastewater treatment plant in the city of Slupsk (northern Poland). The considered scenarios focus on energy savings for aeration, increasing energy recovery via biogas cogeneration and reduction of the CO2 equivalent emission from both direct processes (related...

  • comparison of circular and rectangular narrow esps with longitudinal wire electrode

    Publikacja

    - Rok 2012

    Diesel engines emit fine particles, which are harmful to human and animal health. There are several methods for decrease particulate emission from a diesel engines, but up to now, these methods are not enough effective or very expensive. An electrostatic precipitation was proposed as an alternative method for control of a diesel particulate emission. Therefore, narrow electrostatic precipitators (ESPs) have become a subject of...

  • Recurrent potential pulse technique for improvement of glucose sensing ability of 3D polypyrrole

    In this work, a new approach for using a 3D polypyrrole (PPy) conducting polymer as a sensing material for glucose detection is proposed. Polypyrrole is electrochemically polymerized on a platinum screen-printed electrode in an aqueous solution of lithium perchlorate and pyrrole. PPy exhibits a high electroactive surface area and high electrochemical stability, which results in it having excellent electrocatalytic properties. The...

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  • Disciplines and measures of information resilience

    Publikacja
    • J. Rak
    • M. Jonsson
    • D. Hutchison
    • J. Sterbenz

    - Rok 2017

    Communication networks have become a fundamental part of many critical infrastructures, playing an important role in information delivery in various failure scenarios triggered e.g., by forces of nature (including earthquakes, tornados, fires, etc.), technology-related disasters (for instance due to power blackout), or malicious human activities. A number of recovery schemes have been defined in the context of network resilience...

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  • Quality of bottled waters

    Publikacja

    Bottled water is a product that is purchased by annually increasing numbers of people of all age groups. The quality control of mineral waters tends to concentrate on the determination of anion and cation levels, since it is these that govern the taste, smell and possible medicinal properties of the water. The constantly rising sales of mineral waters bring with them the ever increasing exploitation of their sources. The consequences...

  • CHALK & TALK OR SWIPE & SKYPE?

    Technology in classroom is a matter of heated discussions in the field of education development, especially when multidisciplinary education goes along with language skills. Engineers’ education requires theoretical and practical knowledge. Moreover, dedicated computer skills become crucial for both young graduates and experienced educators on the labor market. Teaching online with or without using different Learning Management...

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  • Biological processes modelling for MBR systems: A review of the state-of-the-art focusing on SMP and EPS

    Publikacja
    • G. Mannina
    • B. Ni
    • J. Mąkinia
    • J. Hermand
    • M. Alliet
    • C. Brepols
    • M. V. Ruano
    • A. Robles
    • M. Heran
    • H. Gulhan... i 2 innych

    - WATER RESEARCH - Rok 2023

    A mathematical correlation between biomass kinetic and membrane fouling can improve the understanding and spread of Membrane Bioreactor (MBR) technology, especially in solving the membrane fouling issues. On this behalf, this paper, produced by the International Water Association (IWA) Task Group on Membrane modelling and control, reviews the current state-of-the-art regarding the modelling of kinetic processes of biomass, focusing on...

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  • Wdrożenie nowych regulacji prawnych w ochronie powietrza atmosferycznego w Polsce

    Publikacja

    - Rok 2013

    W artykule przedstawiono zmiany prawne wynikające z przystosowania dyrektyw 2008/50/WE i 2004/107/WE do prawodawstwa polskiego. Nowe regulacje odnoszące się do ochrony powietrza stanowią jedynie rozbudowanie i modyfikację istniejacych dotychczas przepisów. W ratykule podano istotne informacje wynikajace z decyzji Komisji Europejslkiej 2011/850/UE

  • Three-dimensional modeling and automatic analysis of the human nasal cavity and paranasal sinuses using the computational fluid dynamics method

    Publikacja

    - EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY - Rok 2021

    Purpose The goal of this study was to develop a complete workflow allowing for conducting computational fluid dynam- ics (CFD) simulation of airflow through the upper airways based on computed tomography (CT) and cone-beam computed tomography (CBCT) studies of individual adult patients. Methods This study is based on CT images of 16 patients. Image processing and model generation of the human nasal cavity and paranasal sinuses...

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  • Mitigation of Fake Data Content Poisoning Attacks in NDN via Blockchain

    Publikacja

    Abstract—Information-centric networks struggle with content poisoning attacks (CPAs), especially their stronger form called Fake Data CPA, in which an intruder publisher uploads content signed with stolen credentials. Following an existing graphinfection based approach leveraging the constrained time when stolen credentials are useful, we design a blockchain-based mitigation scheme for Named Data Networking architectures. We postulate...

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  • Computer-Aided Automated Greenery Design—Towards a Green BIM

    Contemporary climate challenges are changing the architect’s awareness, which results in a broader spectrum of interest. The available software enables the design of vegetation, but it is often very limited and requires specialist knowledge. The available software allows the creation of individual solutions based on visual algorithms or writing scripts; however, they are still not common methods used in architecture and urban planning....

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  • SEWAGE SYSTEM CONCEPT FOR KAMIEŃ VILLAGE IN THE COMMUNE OF SZEMUD

    Publikacja

    - Rok 2020

    The aim of this thesis is to solve a disturbing problem, which is illegal sewage discharge, without any previous treatment in a village Kamień, Szemud commune, Poland, by developing a multivariate sewerage system concept. The introduction submits the theory concerning the division of sewer systems as well as the wastewater treatment’s level. Moreover, there is also the problem of rural sanitation presented and main locality –...

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  • Implementation of daylight design strategies in urban planning - barriers to application in Poland

    Publikacja

    - Rok 2015

    This paper reflects on studies done in the area of daylight design methods with regard to principles that can be applied in architecture and urban planning strategies. The paper addresses barriers to the application of new daylight design methods in urban planning, and in particular discusses current Polish building regulations in the context of daylight design. The results of the pilot study carried out among 82 participants show...

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  • Inter-governmental Collaborative Networks for Digital Government Innovation Transfer -Structure, Membership, Operation

    Publikacja

    Digital government refers to the transformation of government organizations and their relationships with citizens, business and each other through digital technology. It entails digital innovation in processes, services, organizations, policies, etc. which are increasingly developed and tested in one country and transferred, after adaptation, to other countries. The process of innovation transfer and the underlying information...

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  • Degradation of the Concrete Railway Track Bed Located in the Vicinity of the Loading Wharf

    The following article describes the damages of the concrete railway track bed at the place of unloading petroleum products located in the immediate vicinity of the cargo berth. The concrete of the track bed has been a subject to degradation as a result of many years of exploitation resulting, inter alia, in its cyclical flooding of petroleum products during the unloading and loading of rail tankers. Repairs carried out in the previous...

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  • An Evaluation Engine for Dynamic Ranking of Cloud Providers

    Publikacja

    - Informatica - Rok 2013

    The paper focuses on creation of an effective dynamic ranking service for IaaS, PaaS and SaaS cloud providers. It considers building a quality model for this purpose along with definition of quality measure- ment procedures. The paper discusses several techniques known from already existing price comparison engines that could be modified and adopted for comparison of cloud providers. A technique for filtering measured data is proposed,...

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  • DETERMINANTS OF INLAND NAVIGATION ON THE VISTULA FROM WARSAW TO GDAŃSK

    Publikacja

    Waterborne transport is the cheapest, the safest and the least harmful to the natural environment. Restoring regular waterway cargo transport will require revitalisation of the existing trans-shipment and logistics infrastructure for commercial inland ports and building new. Transport policy makers must remember that waterborne transport is the most ecological type of transport. It produces only 10% of the gases emitted to the...

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  • Power equalization of AES FPGA implementation

    This paper briefly introduces side channel attacks on cryptographic hardware with special emphasis on differential power analysis(DPA). Based on existing countermeasures against DPA, design method combining power equalization for synchronous and combinatorialcircuits has been proposed. AES algorithm has been implemented in Xilinx Spartan II-E field programmable gate array (FPGA) deviceusing the standard and power-equalized methods....

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  • Inteligentny modeler graficzny w komputerowych systemach wspomagania projektowania budowlanego

    Publikacja

    - Rok 2005

    W pracy przedstawiono Inteligentny Modeler Graficzny (IMG), integrujący proces projektowania w systemach CAD. IMG integruje dwie podstawowe fazy projektowania : fazę konstruowania z fazą analziy konstrukcji. Podstawą integracji stałą się metoda Graphic Data Edition (GDE) rozpoznawania rysunku, oprata na koncepcji Logiki Rozmytej. Metoda GDE pozwoliła na zbudowanie modelera rozmytego, mającego za zadanie rozpoznanie rysunku i wygenerowanie...

  • Automatic Correction of Non-Anechoic Antenna Measurements using Low-Pass Filters

    Publikacja

    Prototype measurements belong to key steps in the development of antenna structures. They are normally performed in expensive facilities, such as anechoic chambers (ACs). Alternatively, antenna performance can be extracted (at a low cost) in non-anechoic conditions upon appropriate post-processing. Unfortunately, existing correction algorithms are difficult to set up and prone to failure, which limits their practical usefulness....

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  • Adaptive Wavelet-Based Correction of Non-Anechoic Antenna Measurements

    Publikacja

    Non-anechoic measurements represent an affordable alternative to evaluation of antenna performance in expensive, dedicated facilities. Due to interferences and noise from external sources of EM radiation, far-field results obtained in non-ideal conditions require additional post-processing. Conventional correction algorithms rely on manual tuning of parameters, which make them unsuitable for reliable testing of prototypes. In this...

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  • Rebuilding Bailey Bridge to Bridge With Bascule Span – A Case Study

    The structural analysis of a road foldable prefabricated steel Bailey- type bridge located over the Tuga River in Żelichowo, Poland is performed in this paper. Interesting and untypical bridge redevelopment performed made it possible to lift the middle foldable bridge span by approximately 4.0 m concerning the existing state. The paper begins with a survey of literature carried out on the investigations of foldable Bailey-type...

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  • A ROLE PLAYING GAME NAME GENERATOR LEARNING ITS CREATIVITY FROM ARKADIA MUD PLAYERS

    Publikacja

    - Rok 2013

    The paper proposes an approach to creative generation of new names for the purposes of Role Playing Games in fantasy realms. The generator based on an existing database of na mes is able to propose a set of new names with regard to demanded attributes, such as: length of the name, sex and race of the character, a given p hrase as the origin for the generated name as well as subjective evaluations from former users. The software...

  • Property revenues (PRs) and expenditures of local government units (LGUs) in Poland

    PRs are new category of local government revenues, which was introduced by changing the law on public finances at the end of 2006 and which took effect in 2007. By principle, these revenues should be converted into property expenditures. Their formalisation did not only allow assessing their absolute size but also a comparison with the longer existing property expenditures. Both categories were subject of analysis in this article....

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  • Valuation of architectural heritage by multicultural student groups

    In this article, the author addresses the education of architecture students in the field of architectural history and the determination of the value of architectural objects. Important changes at present are underway concerning this. Both the role of architectural history in architectural education and content in architectural history curricula is changing. The need for re-evaluation...

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  • The impact of the temperament model on the behavior of an autonomous driver

    Because it is generally believed that the personality and temperament of a human driver influence his/her behavior on the road, the article presents a computational model of the temperament of an autonomous agent - a driver. First, a short review of the four ideas of Galen’s temperament in psychology is presented. Temperament traits are grouped into four other sets, one of which is chosen for implementation in the project of integration...

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  • Design and optimization of a novel compact broadband linearly/circularly polarized wide-slot antenna for WLAN and Wi-MAX applications

    Publikacja

    - RADIOENGINEERING - Rok 2019

    A novel topologically modified structure of a compact low profile wide-slot antenna for broadband applications is presented. The antenna comprises a modified E-shaped slot with unequal arm lengths in the ground plane, and a parasitic quasi-rectangular loop placed coplanar with the feedline. For exciting orthogonal modes with equal amplitude, a single-point feeding technique with an asymmetrical geometry of the coplanar waveguide...

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  • Evolution of the HVDC Link Connecting Offshore Wind Farms to Onshore Power Systems

    Publikacja

    This paper presents an overview of the DC link development and evolution dedicated to HVDC structure for connecting offshore wind power plants to onshore power systems. The growing demand for the green energy has forced investors in power industry to look for resources further out at sea. Hence, the development of power electronics and industrial engineering has enabled offshore wind farms to be situated further from the shore...

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  • Flexural behaviour of concrete slabs reinforced with FRP bars in experiments and according to aci ACI 440.1R guide

    The paper presents research conducted on two concrete slabs reinforced with the carbon composite bars and two other concrete slabs reinforced with basalt composite bars. The carbon bars were plain, while the basalt ones were ribbed. The slabs were experimentally investigated in the flexural state of effort with the concentrated forces applied. The results are compared with the analytical solution proposed in the guide ACI 440.1R-06...

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  • What defines excellent lighting design for humans and animals?

    Publikacja
    • K. M. Zielińska

    - Rok 2009

    What defines excellent lighting design for humans and animals? The answer to the above question is more than com­plex. It is not enough nowadays to design a project to make it aesthetically pleasing. Nor is it sufficient to create nicely lit environments, or simply to achieve the light levels required by the lighting norms or stan­dards. With the new scientific research of the last few de­cades that relates directly or indirectly...

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  • Mechanisms of azole resistance among clinical isolates of Candida glabrata in Poland

    Publikacja

    Candida glabrata is currently ranked as the second most frequently isolated aetiological agent of human fungal infections, next only to Candida albicans. In comparison with C. albicans, C. glabrata shows lower susceptibility to azoles, the most common agents used in treatment of fungal infections. Interestingly, the mechanisms of resistance to azole agents in C. albicans have been much better investigated than those in C. glabrata....

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  • Analiza zmiennych objaśniających i rozbudowa modelu wyboru środka transportu

    Publikacja

    - Rok 2015

    W artykule poddano analizie potrzebę uwzględnienia dodatkowych czynników wpływających na wybór środka transportu w prognozowaniu podróży. Przedstawiono dotychczasowe badania wpływu wybranych czynników na podział zadań przewozowych. W oparciu o wyniki krajowych Kompleksowych Badań Ruchu zostały wykonane analizy zależności udziału podróży transportem zbiorowym w obszarach zurbanizowanych od wybranych czynników zewnętrznych.

  • Book Review

    Acting over the last three decades as an Editor and Associate Editor for a number of international journals in the general area of cybernetics and AI, as well as a Chair and Co-Chair of numerous conferences in this field, I have had the exciting opportunity to closely witness and to be actively engaged in the stimulating research area of machine learning and its important augmentation with deep learning techniques and technologies. From...

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  • Preliminary safety assessment of Polish interchanges

    Publikacja

    - Archives of Transport - Rok 2021

    Interchanges are a key and the most complex element of a road infrastructure. The safety and functionality of interchanges determine the traffic conditions and safety of the entire road network. This applies particularly to motorways and express-ways, for which they are the only way to access and exchange traffic. A big problem in Poland is the lack of comprehensive tools for designers at individual stages of the design process....

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  • Window frame integrable air recuperation minichannel/minigap heat exchanger

    This article describes an evaluation of mini heat exchangers operation as a decentralized mechanical ventilation system with recuperative heat recovery that can be integrated into the window frame. The relatively small yet efficient air recuperation system allows for retrofitting existing buildings by reducing the overall energy consumption and thus the CO2 emissions. The proposed design, unlike existing systems, is easy to scale...

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  • Tackling microplastics pollution in global environment through integration of applied technology, policy instruments, and legislation

    Publikacja
    • T. A. Kurniawan
    • A. Haider
    • A. Mohyuddin
    • R. Fatima
    • M. Salman
    • A. Shaheen
    • H. M. Ahmad
    • H. Al-Hazmi
    • M. H. D. Othman
    • F. Aziz... i 2 innych

    - JOURNAL OF ENVIRONMENTAL MANAGEMENT - Rok 2023

    Microplastic pollution is a serious environmental problem that affects both aquatic and terrestrial ecosystems. Small particles with size of less than 5 mm, known as microplastics (MPs), persist in the environment and pose serious threats to various species from micro-organisms to humans. However, terrestrial environment has received less attention than the aquatic environment, despite being a major source of MPs that eventually...

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  • Street Art and Urban Regeneration. Case Study Gdansk and Rome.

    Publikacja

    - Rok 2016

    Street art plays an important role in urban planning as a transforming engine to regenerate the public spaces and in the processes of participation. The article analyzes two main topics. The first one focuses on the urban serving as a support for spatial and cultural strategies in urban redevelopment projects. The second one is related to the potential of micro urban interventions as a strategy for a wider involvement of inhabitants...

  • Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse

    Publikacja
    • P. Sachadyn
    • X. Zhang
    • L. D. Clark
    • R. K. Naviaux
    • E. Heber-Katz

    - MITOCHONDRION - Rok 2008

    The MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TpsiCloop of the tRNA methionine gene...

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  • Zabytkowa infrastruktura kolejowa jako potencjał krajobrazu kulturowego

    Publikacja

    - Rok 2020

    W dobie obecnych działań rewitalizacyjnych oraz przemian kolejnictwa, prowadzonych lub przewidywanych w licznych miastach Polski, konieczne jest wskazanie wartości, jakie często niesie z sobą infrastruktura kolejowa. Może się ona stać istotnym elementem przekształcanych przestrzeni miejskich – nie tylko pod względem transportowym. Odpowiednio zaplanowane działania pozwalają uchronić przed destrukcją historyczne obiekty, m.in. wprowadzając...

  • Analiza sterowania ułamkowego PIλDμ mocą reaktora jądrowego

    W artykule przedstawiono syntezę regulatora PIλDμ niecałkowitego rzędu dla potrzeb sterowania mocą reaktora jądrowego lekko wodnego określanego, jako typu PWR (Pressurized Water Reactor). W tym celu wykorzystano nieliniowy model matematyczny reaktora PWR o parametrach skupionych obejmujący procesy generacji i wymiany ciepła oraz termicznych efektów reaktywnościowych. Nastawy regulatora PIλDμ niecałkowitego rzędu dobrano w sposób...

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