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Wyniki wyszukiwania dla: VIBROACOUSTIC DIAGNOSTICS
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Synthesis, spectroscopy and computational studies of some biologically important hydroxyhaloquinolines and their novel derivatives
PublikacjaA series crystalline compounds of methyl and phosphinyl derivatives of 2-methylquinolin-8-ol (1a) and related 5,7-dichloro-2-methylquinolin-8-ol (1b) were quantitatively prepared and characterized by microanalysis, IR, UV-vis and multinuclear NMR spectroscopy. Five of them have been characterized by single crystal X-ray diffraction method. The known compounds, 8-methoxy-2-methylquinoline (2a) and 8-methoxyquinoline (2d), were synthesised...
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Forewarned Is Forearmed: Machine Learning Algorithms for the Prediction of Catheter-Induced Coronary and Aortic Injuries
PublikacjaCatheter-induced dissections (CID) of coronary arteries and/or the aorta are among the most dangerous complications of percutaneous coronary procedures, yet the data on their risk factors are anecdotal. Logistic regression and five more advanced machine learning techniques were applied to determine the most significant predictors of dissection. Model performance comparison and feature importance ranking were evaluated. We identified...
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Detection of Toxoplasma gondii Infection in Small Ruminants: Old Problems, and Current Solutions
PublikacjaToxoplasmosis is a parasitic zoonosis of veterinary importance, with implications for public health. Toxoplasma gondii infection causes abortion or congenital disease in small ruminants. Moreover, the consumption of infected meat, cured meat products, or unpasteurized milk and dairy products can facilitate zoonotic transmission. Serological studies conducted in various European countries have shown the high seroprevalence of specific...
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Machine-aided detection of SARS-CoV-2 from complete blood count
PublikacjaThe current gold standard for SARS-CoV-2 detection methods lacks the functionality to perform population screening. Complete blood count (CBC) tests are a cost-effective way to reach a wide range of people – e.g. according to the data of the Central Statistical Office of Poland from 2016, there are 3,000 blood diagnostic laboratories in Poland, and 46% of Polish people have at least one CBC test per year. In our work, we show...
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Assessment of particular abdominal aorta section extraction from contrast-enhanced computed tomography angiography
PublikacjaThe aim of this work is to improve the accuracy of extraction of a particular abdominal aorta section and to reduce the distortion in three-dimensional Computed Tomography Angiography (CTA) images. Imaging modality and quality plays crucial role in the medical diagnostic process, thus ensuring high quality of images is essential at every stage of acquisition and processing.Noise is defined as a disturbance of the image quality...
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Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
PublikacjaThe early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to investigate the association...
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Adaptacyjny algorytm filtracji sygnału fonokardiograficznego wykorzystujący sztuczną sieć neuronową
PublikacjaPodstawowym problemem podczas projektowania systemu autodiagnostyki chorób serca, bazującego na analizie sygnału fonokardiograficznego (PCG), jest konieczność zapewnienia, niezależnie od warunków zewnętrznych, sygnału o wysokiej jakości. W artykule, bazując na zdolności Sztucznej Sieci Neuronowej (SSN) do predykcji sygnałów periodycznych oraz quasi-periodycznych, został opracowany adaptacyjny algorytm filtracji dźwięków serca....
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Detekcja i lokalizacja nieprzewodzenia tranzystorów falownika napięcia na podstawie analizy prądu obciążenia
PublikacjaPrzedstawiono nową metodę detekcji i lokalizacji nieprzewodzenia tranzystorów w falownikach napięcia zasilających silniki indukcyjne małej mocy. Metoda bazuje na monitorowaniu wartości dwóch sygnałów dia-gnostycznych. Pierwszy z nich, wskaźnik braku przepływu prądu, wykorzystano w celu detekcji uszkodzeń. Drugi, stosunek wartości średniej prądu do wartości średniej bezwzględnej, zawiera informacje umożliwiające lokalizację uszkodzonych...
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The semi-Markov model of the process of appearance of sea-going ship propupsion system ability and inability states in application to determining the reliablity of these systems
PublikacjaThe article presents possible application of the theory of semi-Markov processes in creating the eight-state model of the process of appearance of the propulsion systems ability and inability states on sea-going vessels performing transportation tasks in a relatively long operating time t (t → ∞). The model has been proved to be able to be successfully used for determining the reliability of the abovementioned systems. The probability...
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In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
PublikacjaBACKGROUND. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans...
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Deformation Analysis of a Composite Bridge during Proof Loading Using Point Cloud Processing
PublikacjaRemote sensing in structural diagnostics has recently been gaining attention. These techniques allow the creation of three-dimensional projections of the measured objects, and are relatively easy to use. One of the most popular branches of remote sensing is terrestrial laser scanning. Laser scanners are fast and efficient, gathering up to one million points per second. However, the weakness of terrestrial laser scanning is the...
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Nondestructive global corrosion measurement using guided wavefield data
PublikacjaMetallic structures often face degradation, and corrosion ranks among the most prevalent forms of deterioration. Accurate quantification of corrosion is crucial, especially for structures exposed to harsh environmental conditions, such as marine vessels and offshore installations. Because the traditional measurement methods based on scanning by ultrasonic gauge are time-consuming and provide only rough information on the thickness...
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Exploring the landscape of automatic cerebral microbleed detection: A comprehensive review of algorithms, current trends, and future challenges
PublikacjaThis paper provides the first review to date which gathers, describes, and assesses, to the best of our knowledge, all available publications on automating cerebral microbleed (CMB) detection. It provides insights into the current state of the art and highlights the challenges and opportunities in this topic. By incorporating the best practices identified in this review, we established guidelines for the development of CMB detection...
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Testing the Positioning Accuracy of GNSS Solutions during the Tramway Track Mobile Satellite Measurements in Diverse Urban Signal Reception Conditions
PublikacjaMobile Global Navigation Satellite System (GNSS) measurements carried out on the railway consist of using satellite navigation systems to determine the track geometry of a moving railway vehicle on a given route. Their purposes include diagnostics, stocktaking, and design work in railways. The greatest advantage of this method is the ability to perform measurements in a unified and coherent spatial reference system, which...
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THE MODELLING OF ACCUMULATION AND DISSIPATION OF ENERGY IN MECHANICAL DRIVE SYSTEM
PublikacjaThis paper presents a modelling of accumulation and dissipation energy in simple drive system. The simple drive system is presented by laboratory stand designed for calculate fatigue life of material for bending and rotation tests pieces. The laboratory stand was prepared to diagnosis of fatigue life of material by use energetic methods. This idea was submitted as utility model to Polish Patent Office. This laboratory stand gives...
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Anatomy of noise in quantitative biological Raman spectroscopy
PublikacjaRaman spectroscopy is a fundamental form of molecular spectroscopy that is widely used to investigate structures and properties of molecules using their vibrational transitions. It relies on inelastic scattering of monochromatic laser light irradiating the specimen. After appropriate filtering the scattered light is dispersed onto a detector to determine the shift from the excitation wavelength, which appears in the form of...
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Cancer immune escape: the role of antigen presentation machinery
PublikacjaThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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THE ROLE OF INFERENCE IN MOBILE MEDICAL APPLICATION DESIGN
PublikacjaIn the early 21st century, artificial intelligence began to be used to process medical information. However, before this happened, predictive models used in healthcare could only consider a limited number of variables, and only in properly structured and organised medical data. Today, advanced tools based on machine learning techniques - which, using artificial neural networks, can explore extremely complex relationships - and...
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublikacjaHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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Optoelectronic device for hematocrit measurements
PublikacjaAn optoelectronic system for measurements of hematocrit level (HCT) in the whole human blood is presented. Proposed system integrates a dedicated optoelectronic sensor, a microcontroller and a small LCD display in a low cost, battery-powered, handheld device. Chosen method for determining blood hematocrit level is based on optical properties of whole blood in visible and NIR wavelength range. Measurements with the use of proposed...
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Experimental bases for the rail track surface damage detection system
PublikacjaA diagnosis of rail surface is generally based on the classical method of direct assessment and track geometry measurements. Identification and qualification of inequality and damage on the surface rails is depend on the skills and experience person who conducting inspection. In times of increasing exploitation of railways, infrastructure managers decide to use systems supporting the assessment of technical condition of the railways....
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Nowe substancje psychoaktywne CZ. II. SYNTETYCZNE KANNABINOIDY - CHARAKTERYSTYKA, METODY OZNACZANIA I WYZWANIA ANALITYCZNE
PublikacjaDo nielegalnego obrotu co roku trafiają nowe związki o działaniu psychoaktywnym. Dostęp do takich substancji nie jest trudny, gdyż są one łatwo dostępne w wielu krajach, głównie w sklepach internetowych. Ponadto, organy ścigania i wymiar sprawiedliwości nie nadążają z wprowadzaniem tych substancji na listy substancji zakazanych przez co ich kontrola jest bardzo utrudniona. Syntetyczne kannabinoidy to grupa związków chemicznych,...
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Transiluminacyjne monitorowanie stanu przestrzeni podpajęczynówkowej
PublikacjaTransiluminacja tkanek ludzkiego ciała w celach diagnostycznych jest stosowana od ponad stu lat. Metoda transiluminacji w bliskiej podczerwieni z rozpraszaniem zwrotnym (NIRT-BSS) umożliwia ciągłe, bezinwazyjne monitorowanie zmian szerokości przestrzeni podpajęczynówkowej, które może być cennym narzędziem w ocenie zagrożenia obrzękiem mózgu. W rozprawie przedstawiono optyczny model rozchodzenia się promieniowania podczerwonego...
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Caring for Children with Dravet Syndrome: Exploring the Daily Challenges of Family Caregivers
PublikacjaWhile Polish studies focus on the symptoms, causes and treatment of people suffering from Dravet syndrome (DS), much less is known about the situation of the family caregivers of DS children. This study was designed to explore the experiences, daily challenges and needs related to caring for DS children. An anonymous self-administered online questionnaire was developed. Thesurvey was completed by 75 family caregivers affiliated...
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Two-photon perimetry utilizing picosecond laser
PublikacjaAge-related impairments are becoming more and more severe for aging societies. The sensory organ diseases are particularly troublesome as they exclude seniors from their everyday activity. Therefore, maintaining good quality eyesight is essential for normal functioning. New medical therapies help restrain age-related changes, but still, monitoring is essential to the treatment process. Humans do not have the natural ability to...
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Clinical studies of detecting COVID-19 from exhaled breath with electronic nose
PublikacjaThe COVID‑19 pandemic has attracted numerous research studies because of its impact on society and the economy. The pandemic has led to progress in the development of diagnostic methods, utilizing the polymerase chain reaction (PCR) as the gold standard for coronavirus SARS‑CoV‑2 detection. Numerous tests can be used at home within 15 min or so but of with lower accuracy than PCR. There is still a need for point‑of‑care tests available...
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An additional ultrasonographic sign of Hashimoto’s lymphocytic thyroiditis in children
PublikacjaWe present an additional sonographic sign of Hashimoto’s thyroiditis (HLT), increasing the specifi city of this method in pediatric populations. Methods: A total of 98 children (mean age 12.7 years, range 7–17 years) were selected from the registry of the endocrinology outpatient department. All subjects met the diagnostic criteria for HLT. All children underwent a prospective thyroid ultrasound examination with special attention...
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The Emission and Combustion Characteristics of Marine Diesel Engine with Extreme Throttled of Air or Exhaust Ducts
PublikacjaPresented paper shows the results of the laboratory tests on the relationship between the extreme throttling of both air intake duct and exhaust gas duct and gaseous emission from the marine engine. The object of research is a laboratory, 4-stroke, DI diesel engine, operated at loads from 50 kW to 250 kW at a constant speed equal to 750 rpm. During the laboratory tests the thermodynamic and exhaust gas emission characteristics...
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Diagnostyka ultradźwiękowa mostowej belki prefabrykowanej typu T metodą młoteczkową
PublikacjaZastosowanie prefabrykacji w budowie obiektów mostowych pozwala optymalizować zużycie energii i materiałów i tym samym redukować koszty budowanego obiektu. Prefabrykowane belki sprężone mogą występować jako elementy kablobetonowe wykonywane bezpośrednio na placu budowy lub powstawać w zakładzie prefabrykacji jako elementy strunobetonowe. Elementy prefabrykowane wytwarzane w warunkach przemysłowych muszą spełniać wymagania wysokiej trwałości,...
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Tests on lateral resistance in railway track during operation of tamping machine
PublikacjaArtykuł prezentuje koncepcję prowadzenia badań oporów poprzecznych w trakcie procesu regulacji geometrycznej toru kolejowego za pomocą podbijarki. Jest to zatem kontynuacja badań nad zastosowaniem podbijarki torowej w diagnostyce toru bezstykowego; wcześniej zajmowano się kwestią określania sił podłużnych w szynach. Przedstawiono sposób wyznaczania oporów poprzecznych polegający na ciągłej rejestracji przemieszczenia oraz siły...
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ZASTOSOWANIE STATYSTYKI F ROZKŁADU FISHERA-SNEDECORA DO OCENY ISTOTNOŚCI WPŁYWU ZMIAN STOPNIA KOMPRESJI SILNIKA O ZS NA ŚREDNIĄ WARTOŚĆ MIĘDZYSZCZYTOWĄ TEMPERATURY SPALIN WYLOTOWYCH
PublikacjaW artykule omówiono wpływ zmian stopnia kompresji na parametry pracy silnika o ZS, m.in. na temperaturę spalin wylotowych. Przedstawiono budowę stanowiska laboratoryjnego, na którym przeprowadzono badania eksperymentalne. Scharakteryzowano, w jaki sposób w istniejącym silniku wprowadzano faktyczne zmiany stopnia kompresji. Zaprezentowano program badań eksperymentalnych uwzględniający dostępne stanowisko badawcze i jego możliwości...
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Możliwości integracji projektów sztuki nowych mediów w procesy odnowy przestrzeni miejskiej
PublikacjaZadaniem badawczym podjętym w rozprawie było wykazanie możliwość integracji projektów sztuki nowych mediów w procesy odnowy przestrzeni miejskiej. Wyodrębniono cztery etapy procesów odnowy miast: diagnozę, planowanie, realizację oraz ewaluację. Wskazano, że na etapie diagnozy sztuka nowych mediów może między innymi wspierać proces zbierania i wizualizacji danych, informować mieszkańców o stanie środowiska miejskiego. Na etapie...
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Gold nanoparticles evaluation using functional optical coherence tomography
PublikacjaThe main object of this research was to assess the ability to characterize the gold nanoparticles using optical modalities like optical coherence tomography. Since the nanoparticles, especially gold one, have been very attractive for medical diagnosis and treatment the amount of research activities have been growing rapidly. The nanoparticles designed for different applications like contrast agents or drugs delivery change the...
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Viability of decisional DNA in robotics
PublikacjaThe Decisional DNA is an artificial intelligence system that uses prior experiences to shape future decisions. Decisional DNA is written in the Set Of Experience Knowledge Structure (SOEKS) and is capable of capturing and reusing a broad range of data. Decisional DNA has been implemented in several fields including Alzheimer’s diagnosis, geothermal energy and smart TV. Decisional DNA is well suited to use in robotics due to the...
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Optimized 5-hour multiplex PCR test for the detection of tinea unguium: performance in a routine PCR laboratory
PublikacjaWe recently reported the development of a 5-hour multiplex PCR test for the detection of tinea unguium and the optimization of this test by the inclusion of an inhibition control. Here we report the performance of this procedure as used in a routine clinical laboratory as compared to conventional microscopy and culture-based techniques performed in a mycology reference laboratory. We found in processing 109 samples that 22 (20.2%)...
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From hobbies, straightforward analysis to serious research – the road to phd degree
PublikacjaThe illustration of the main articles goal is an example of author's academic career course, the aim of which is to obtain a doctoral degree in the field of geodesy and cartography. Today, the most important thing for the young scientist is the devotion to research in certain field of science, which is interested for the large community of scientists. From a psychological point of view, a unity of interest and experiments must...
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Virulence analysis and antibiotic resistance of Klebsiella pneumoniae isolates from hospitalised patients in Poland
PublikacjaKlebsiella pneumoniae (KP) is a nosocomial pathogen causing difficult-to-treat infections. The presence of virulence genes and antibiotic resistance of 109 KP isolates from hospitalized patients were investigated. Among them, 68.8% were multi-drug resistant (MDR) and 59.6% produced extended-spectrum beta-lactamases (ESBLs). Metallo-β-lactamases (MBLs) were produced by 22% of isolates (mainly from anus), including 16.5% of isolates...
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Managing Unemployment under COVID-19 Conditions (States of Emergency or Crisis)
PublikacjaRising unemployment is one of the consequences of the COVID-19 pandemic in many countries. This, in turn, has forcedpolicymakers to respond immediately with policy tools to minimize unemployment. The purpose of our study is to contribute toempirical knowledge by looking at activities of 40 local government units to counteract unemployment in the cross-border regionon the Polish side. In doing this, our study contributes to the...
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Increased concentration of Taq DNA polymerase as a solution for GC-rich templates from clinical and environmental samples
PublikacjaDNA polymerase is an enzyme which plays crucial role in replication and DNA repair. It found application in PCR (polymerase chain reaction) where catalyses process of in vitro DNA synthesis. To meet the demands posed by mod- ern diagnostic, molecular biology or genetic engineering it is necessary to improve DNA polymerases to obtain new or better features useful in these fields. So far implemented modifications in majority are...
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Damage Detection in the Wind Turbine Blade Using Root Mean Square and Experimental Modal Parameters
PublikacjaThe paper presents results of an experimental study related to a non-destructive diagnostic technique used for preliminary determination the location and size of delamination in composite coatings of wind turbine blades. The proposed method of damage detection is based on the analysis of the ten first mode shapes of bending vibrations, which correspond to displacements of rotor blades perpendicular to the rotor plane. Modal parameters...
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The Idea of Using Bayesian Networks in Forecasting Impact of Traffic-Induced Vibrations Transmitted through the Ground on Residential Buildings
PublikacjaTraffic–induced vibrations may constitute a considerable load to buildings. In this paper, vibrations transmitted through the ground caused by wheeled vehicles are considered. This phenomenon may cause cracking of plaster, cracks in load-bearing elements or even, in extreme cases, collapse of the whole structure. Measurements of vibrations of real structures are costly and laborious. Therefore, the aim of the present paper is to...
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Thermal efficiency investigations on the self-ignition test engine fed with marine low sulfur diesel fuels
PublikacjaWithin the article an issues of implementing the new kinds of marine diesel fuels into ships’ operation was described taking into ac-count restrictions on the permissible sulphur content introduced by the International Maritime Organization. This is a new situation for ship owners and fuel producers, which forces the necessity to carry out laboratory research tests on especially adapted engine stands. How to elaborate the method...
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Nanoparticles: Taking a Unique Position in Medicine
PublikacjaThe human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In parallel with our history of civilization, interest in scientific approaches to unravel mechanisms underlying natural phenomena has been developing. Recent years have witnessed unprecedented growth in research in the area of pharmaceuticals and medicine. The optimism that nanotechnology (NT) applied to medicine and drugs is taking serious...
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Leakage Current Measurements of Surge Arresters
PublikacjaThe paper presents the methods of assessing the technical condition of varistor surge arresters used in laboratory tests and in operation—performed without disconnecting the arresters from the network. The analysis of the diagnostic methods was supplemented with the results of the measurements of the leakage current of arresters coming directly from their production and used in the power industry. Among the available methods of...
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Sieć sensorowa do rejestracji drgań górnej sieci trakcyjnej w celach diagnostyki eksploatacyjnej
PublikacjaWraz ze wzrostem prędkości kolejowych pojazdów elektrycznych zwiększają się wymagania utrzymania sieci trakcyjnej w odpowiednim stanie technicznym. Ciągły monitoring i diagnostyka pozwalają wykrywać pogarszającą się jakość odbioru prądu z sieci jezdnej. Jedną z metod jest umieszczenie czujników przyspieszenia na przewodzie jezdnym. Analiza przebiegu przyspieszenia pozwala określić jakość współpracy sieci jezdnej z pantografem....
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Towards Designing an Innovative Industrial Fan: Developing Regression and Neural Models Based on Remote Mass Measurements
PublikacjaThis article presents the process of the construction and testing a remote, fully autonomous system for measuring the operational parameters of fans. The measurement results obtained made it possible to create and verify mathematical models using linear regression and neural networks. The process was implemented as part of the first stage of an innovative project. The article presents detailed steps of constructing a system to...
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Modelowanie dynamiki odbieraka prądu pojazdu kolejowego do celów diagnostycznych
PublikacjaNiewłaściwa współpraca odbieraka prądu i sieci trakcyjnej, w trudnych warunkach lokalnych, może prowadzić do uszkodzenia sieci trakcyjnej i pantografu. W ramach rozwoju metod monitoringu i diagnostyki dla tych podsystemów, tworzone są nowe i dokładniejsze narzędzia symulacyjne, których zakres obejmuje modelowanie zarówno napowietrznej sieci trakcyjnej i pantografu, a także ich dynamicznego oddziaływania. Głównym celem jest dokładniejsza...
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Określanie oporu poprzecznego podsypki podczas pracy podbijarki torowej
PublikacjaW Politechnice Gdańskiej od wielu lat są prowadzone prace badawcze nad wykorzystaniem podbijarki torowej w diagnostyce toru kolejowego. Chodzi o to, żeby podczas jej bieżącej pracy można było określać stan naprężeń w szynach oraz wartości oporów poprzecznych. W pracy przedstawiono opis przeprowadzonych badań eksperymentalnych dotyczących oporów rusztu torowego, zastosowany system pomiarowy oraz analizę uzyskanych wyników. Wartości...
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Wytyczne dotyczące diagnostyki inwazyjnych zakażeń grzybiczych u pacjentów hematologicznych i onkologicznych
PublikacjaInwazyjne zakażenia grzybicze (ang. invasive fungal diseases - IFD) są główną przyczyną zachorowań i śmiertelności, szczególnie u pacjentów z nowotworami hematologicznymi. Grzyby, które są najczęstszymi przyczynami schorzeń u tego typu pacjentów to Aspergillus spp. oraz Candida albicans. Gatunki Candida nie-albicans oraz rosnąca liczba innych grzybów (np. Zygomycetes, Trichosporon, Fusarium spp.) są także coraz częściej wykrywane....
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Advanced Modeling of Management Processes in Information Technology
PublikacjaThis book deals with the issues of modeling management processes of information technology and IT projects while its core is the model of information technology management and its component models (contextual, local) describing initial processing and the maturity capsule as well as a decision-making system represented by a multi-level sequential model of IT technology selection, which acquires a fuzzy rule-based implementation...