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Search results for: Roman rural sites
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Targeting DNA Topoisomerase II in Antifungal Chemotherapy.
PublicationTopoisomerase inhibitors have been in use clinically for the treatment of several diseases for decades. Although those enzymes are significant molecular targets in antibacterial and anticancer chemotherapy very little is known about the possibilities to target fungal topoisomerase II (topo II). Raising concern for the fungal infections, lack of effective drugs and a phenomenon of multidrug resistance underlie a strong need to expand...
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Recombinant !ermostable AP Exonuclease from Thermoanaerobacter tengcongensis: Cloning, Expression, Purification, Properties and PCR Application
PublicationApurinic/apyrimidinic (AP) sites in DNA are considered to be highly mutagenic and must be corrected to preserve genetic integrity, especially at high temperatures. !e gene encoding a homologue of AP exonuclease was cloned from the thermophilic anaerobic bacterium Thermoanaerobacter tengcongensis and transformed into Escherichia coli. The protein product showed high identity (80%) to human Ape1 nuclease, whereas to E. coli exonuclease...
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Investigation of environmental influences to the precise GNNS solutions
PublicationThe results presented in this paper concern investigation of environmental influences to GNNS coordinates on the example of ASG-EUPOS network. The problem of the impact of environmental effects is crucial for observing gravity. Satellite systems are not as susceptible to changes in local hydrology or atmospheric effects, although significant influences are clearly visible in the change of coordinates. The authors analyzed daily...
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Assessment of River Water Quality and Pollution Status Using Physicochemical and Biometrics, Awetu River, Ethiopia
PublicationThe surface water is contaminated by a variety of synthetic organic and inorganic compounds, chemicals, and nutrients; due to this reason, the quality of the water resources of Ethiopia is declining at an alarming rate, resulting in severe environmental degradation. The main objective of the study was to recognize the pollution status river for the study area by physicochemical parameters and the extent of microbial environmental...
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Resonances and Dissociative Electron Attachment in HNCO
PublicationIn a combined experimental and theoretical study, we probe the dissociative electron attachment in isocyanic acid HNCO. The experimental absolute cross section for the NCO− fragment shows a sharp onset and fine structures near the threshold. The autoionizing state responsible for the dissociative attachment is found in both the R-matrix calculation and using analytic continuation in the coupling constant. The involved A' resonance...
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The role of interleukin 16 in the pathogenesis of selected skin diseases
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Effect of Water Content in Ethylene Glycol Solvent on the Size of ZnO Nanoparticles Prepared Using Microwave Solvothermal Synthesis
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Phase Transitions in Pores: Experimental and Simulation Studies of Melting and Freezing
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Effect of preparation conditions on superconducting properties of (Bi,Pb)-Sr-Ca-Cu-O glass-ceramics
PublicationPraca przedstawia wpływ warunków krystalizacji na właściwości nadprzewodzące nadprzewodników wysokotemperaturowych (Bi,Pb)-Sr-Ca-Cu-O otrzymanyh metodą krystalizacji w fazie stałej. Nadprzewodniki otrzymano poprzez wygrzewanie amorficznego materiału o składzie (Bi0.8Pb0.2)4Sr3Ca3Cu4Ox w temperaturze pomiędzy 750°C i 865°C przez czas od 1 minuty do 43 godzin. Najlepsze właściwości, w w tym dużą gęstość prądu krytycznego otrzymano...
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Advanced Assessment of the Endogenous Hormone Level as a Potential Biomarker of the Urogenital Tract Cancer
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The incidences of other primary cancers in patients with mycosis fungoides and Sézary syndrome
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Different molecular organization of two carotenoids, lutein and zeaxanthin, in human colon epithelial cells and colon adenocarcinoma cells
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Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms. Does the Form X Exist?
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Structure – chiroptical properties relationship of cisoid enones with an α-methylenecyclopentanone unit
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Prime-Boost Vaccination with Toxoplasma Lysate Antigen, but Not with a Mixture of Recombinant Protein Antigens, Leads to Reduction of Brain Cyst Formation in BALB/c Mice
PublicationIntroduction Infection with the ubiquitous parasite Toxoplasma gondii is a threat for immunocompro- mised patients and pregnant women and effective immune-prophylaxis is still lacking. Methods Here we tested a mixture of recombinant T . gondii antigens expressed in different develop- mental stages, i.e., SAG1, MAG1 and GRA7 (SMG), and a lysate derived from T . gondii tachyzoites (TLA) for prophylactic vaccination against cyst formation....
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The Effects of Roadside Hazards on Road Accident Severity
PublicationThe risk of becoming involved in an accident emerges when elements of the transport system do not operate properly (man – vehicle – road – roadside). The road, its traffic layout andsafety equipment have a critical impact on road user safety. This gives infrastructural work a priority in road safety strategies and programmes. Run-off-road accidents continue to be one of the biggest problems of road safety with consequences including...
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SEWAGE SYSTEM CONCEPT FOR KAMIEŃ VILLAGE IN THE COMMUNE OF SZEMUD
PublicationThe aim of this thesis is to solve a disturbing problem, which is illegal sewage discharge, without any previous treatment in a village Kamień, Szemud commune, Poland, by developing a multivariate sewerage system concept. The introduction submits the theory concerning the division of sewer systems as well as the wastewater treatment’s level. Moreover, there is also the problem of rural sanitation presented and main locality –...
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Assessment of Alterations in Settlement Patterns of Agricultural Landscape in the Example of Kashubia in Poland
PublicationTraditional agricultural landscapes are heavily exposed to change due to their relatively low agricultural productivity. However, they represent cultural values of great importance in maintaining the resilience of the environment and society. Although their cultural potential is important for sustainable development, it is still insufficiently recognized. The article fills this gap by examining old farmstead buildings as a distinguishing...
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Safety Assessment of the Regional Warmia and Mazury Road Network Using Time-Series Analysis
PublicationWarmia and Mazury still belongs to the areas with the smallest transport accessibility in Europe. Unsatisfactory state of road infrastructure is a major barrier to the development of the regional economy, impacting negatively on the life conditions of the population. Also in terms of road safety Warmia and Mazury is one of the most endangered regions in Poland. The Police statistics show that beside a high pedestrian risk observed...
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Possibilities of Phoslock® application to remove phosphorus compounds from wastewater treated in hybrid wetlands
PublicationTreatment wetland technologies for wastewater treatment can be easily applied for removal of all pollutants except phosphorous. They are applicable in a small towns and rural areas, places where conventional wastewater treatment plant cannot properly operate because of common economic constraints. In Poland only the 8% of rural areas are equipped with sewer system, thus treatment wetlands might be an alternative, effective and...
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Measures of Functional Reliability of Two-Lane Highways
PublicationRural two-lane highways are the most common road type both in Poland and globally. In terms of kilometres, their length is by far greater than that of motorways and expressways. They are roads of one carriageway for each direction, which makes the overtaking of slower vehicles possible only when there is a gap in the stream of traffic moving from the opposite direction. Motorways and express roads are dual carriageways that are...
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Wybrane problemy geotechniczne na terenach zurbanizowanych na przykładzie Trójmiasta
PublicationWybrane, współczesne problemy geotechniczne na terenach zurbanizowanych, miejskich i poprzemysłowych na przykładzie Trójmiasta. Dwie grupy problemów związane z podłożem oraz z otoczeniem inwestycji. Problemy związane z wodą gruntową i jej przepływem, z zanieczyszczeniami oraz pozostałościami budowlanymi z przeszłości. Sąsiedztwo zabudowy i brak miejsca. Przykłady z zrealizowanych obiektów budowlanych. Europejskie Centrum Solidarności,...
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Digitalization of Building Site Management in the Construction Industry
PublicationWith Industry 4.0, a digital transformation has started in the construction industry. However, 4.0 technologies have difficulties in the integration of digital systems due to the diversity and complexity of the processes in the construction industry. Multidisciplinary work in architectural projects and the need for high productivity require digital renovation planning in the construction industry. The application of the technologies...
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The efficiency of pollutants removal and concepts on improvement for single-family TWs
PublicationIn the rural areas building of sewerage systems and central wastewater treatment plants (WWTPs) often brings too high costs, due to high distances from one farm to another and terrain configuration. Individual treatment systems for each farm are a good solution. Theteratment wetlands for nine individual farms were constructed in Kaszubian Lake District in summer and autumn 2009. Three configurations of hydrophyte beds were chosen....
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Voltage profiles improvement in a power network with PV energy sources – results of a voltage regulator implementation
PublicationThe constant increase in the number of photovoltaic (PV) energy sources in distribution networks is the cause of serious voltage problems. The networks built at least a dozen years ago are not provided for the installation of a large number of micro-sources. It happens that the previously properly functioning power networks are not able to provide to consumers power with the required parameters, after installing many PV sources....
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Trace Metal Contamination of Bottom Sediments: A Review of Assessment Measures and Geochemical Background Determination Methods
PublicationThis paper provides an overview of different methods of assessing the trace metal (TM) contamination status of sediments affected by anthropogenic interference. The geochemical background determination methods are also described. A total of 25 papers covering rivers, lakes, and retention tanks sediments in areas subjected to anthropogenic pressure from the last three years (2019, 2020, and 2021) were analysed to support our examination...
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Monitorowanie oddziaływania ruchu kolejowego na środowisko - koncepcje i metody realizacji.
PublicationW artykule przedstawiono podstawowe założenia projektu badawczego, realizowanego w ramach Wspólnego Przedsięwzięcia NCBR i PKP PLK pn. „Badania i Rozwój w Infrastrukturze Kolejowej – BRIK 2”, dotyczącego opracowania systemu monitorującego, integrującego i przetwarzającego gromadzone dane związane z hałasem i drganiami na potrzeby zarządzania procesami utrzymaniowymi i inwestycyjnymi zarządcy infrastruktury kolejowej. W efekcie...
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Bystander Effects Induced by Medium From Irradiated Cells: Similar Transcriptome Responses in Irradiated and Bystander K562 Cells
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Digital image transmission simulation using the PL-log-MAP turbo decoding algorithm
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High pressure impact on changes in potato starch granules
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Pro-Health and Anti-Cancer Activity of Fungal Fractions Isolated from Milk-Supplemented Cultures of Lentinus (Pleurotus) Sajor-caju
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Stellate cells in livers of dogs with portal vein hypoperfusion
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Requirements and Effects of Surface Drip Irrigation of Mid-Early Potato Cultivar Courage on a Very Light Soil in Central Poland
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Changes in Water Quality for Sprinkler Irrigation in Selected Lakes of the Poznan Lake District
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Identification of lipid fraction constituents from grasshopper (Chorthippus spp.) abdominal secretion with potential activity in wound healing with the use of GC–MS/MS technique
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Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine
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Olfactory and tissue markers of fear in mammals including humans
PublicationW pracy przedstawiono informacje na temat:-klasyfikacji i budowy chemicznej związków chemicznych zaliczanych do grupy feromonów,-ich rola w funkcjonowaniu organizmów żywych w tym także organizmu ludzkiego,wyników badań prowadzonych z wykorzystaniem komory ekspozycyjnej własnej konstrukcji,metodyk analitycznych wykorzystywanych do oznaczania śladowych zawartości feromonów w próbkach wydychanego powietrza.
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
PublicationA wide spectrum of brain rhythms are engaged throughout the human cortex in cognitive functions. How the rhythms of various low and high frequencies are spatiotemporally coordinated across the human brain during memory processing is inconclusive. They can either be coordinated together across a wide range of the frequency spectrum or induced in specific bands. We used a large dataset of human intracranial electroencephalography...
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Discriminatory expressions, the young and social networks: The effect of gender
PublicationIn the framework of the «Project I: CUD» (Internet: Creatively Unveiling Discrimination), carried out in the United Kingdom, Italy, Belgium, Romania and Spain, we conducted a study into the expressions of discrimination used by young people on social network sites. To do so we designed a methodological strategy for detecting discriminatory content in 493 Facebook profiles and used this strategy to collect 363 examples for further...
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Effects of Na+, K+ and B3+ Substitutions on the Electrical Properties of La10Si6O27 Ceramics
PublicationDoping of Na and K at La sites and of B at Si site in La10Si6O27 with oxyapatite structure and fabrication of their ceramics were made by the solid-state reaction method. It was found that partial substitution of Na+ and K+ on La sites decreased the sinterability of the La10Si6O27 based ceramics, whereas partial substitution of B3+ on the Si site improved the sinterability. Na+ and K+ substitutions in La10−xNaxSi6O27−x and La10−xKxSi6O27−x...
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Time-Gating method with automatic calibration for accurate measurements of electrically small antenna radiation patterns in Non-Anechoic environments
PublicationNon-anechoic sites represent a cheap alternative to measurements of antennas in dedicated facilities. However, due to a high noise—from the external EM signal sources and multipath interferences—the quality of radiation patterns obtained in non-anechoic conditions is poor. The characteristics can be corrected using a time-gating method (TGM), which involves filtering of the noise based on temporal analysis of the measured signals....
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The role of isolated farmsteads in the open landscape protection on the example of Kashubia
PublicationAs a result of the social and economic transformation of rural areas, open landscapes are disappearing. Former farmsteads are being devastated or beginning to lose their landscape context due to the spread of residential building development. At the same time, in many places, the farmstead form is clearly legible and remains an element with which the view is structured and enriched. The article was aimed at drawing attention to...
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Restrained differential of a graph
PublicationGiven a graph $G=(V(G), E(G))$ and a vertex $v\in V(G)$, the {open neighbourhood} of $v$ is defined to be $N(v)=\{u\in V(G) :\, uv\in E(G)\}$. The {external neighbourhood} of a set $S\subseteq V(G)$ is defined as $S_e=\left(\cup_{v\in S}N(v)\right)\setminus S$, while the \emph{restrained external neighbourhood} of $S$ is defined as $S_r=\{v\in S_e : N(v)\cap S_e\neq \varnothing\}$. The restrained differential of a graph $G$ is...
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Automatic evaluation of information credibility in Semantic Web and Knowledge Grid
PublicationThis article presents a novel algorithm for automatic estimation of information credibility. It concerns information collected in Knowledge Grid and Semantic Web. Possibilities to evaluate the credibility of information in such structures are much greater than those available for WWW sites which use natural language. The rating system presented in this paper estimates credibility automatically on the basis of the following metrics:...
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CMMI - an Assurance of Transferability of Knowledge andProjects in a Distributed Enterprise
PublicationCMMI (Capability Maturity Model Integrated)is a reference model fordefining and performing processes in software and systems engineeringorganizations.An organization implementing CMMI,among other things,assures thatacit knowledge is properly externalized into formal knowledge.This externalization gives an organization opportunity to assure that knowledge and development projects are easily transferable across adistributed enterprise...
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The Fate of BTEX Compounds in Ambient Air
PublicationAs a result of the industrialization and urbanization in the world, human pressure on the environment is intensifying, leading to detrimental changes in both biotic and abiotic compartments. One of the many consequences of this state of affairs is the increasing rate of emission into the atmosphere of volatile organic compounds, including the so-called BTEX (benzene, ethylbenzene, toluene, xylenes) compounds. The authors review...
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Environmental fate of BTEX compounds in ambient air
PublicationAs a result of the industrialization and urbanization in the world, human pressure on the environment is intensifying, leading to detrimental changes in both biotic and abiotic compartments. One of the many consequences of this state of affairs is the increasing rate of emission into the atmosphere of volatile organic compounds, including the so-called BTEX (benzene, ethylbenzene, toluene, xylenes) compounds. The article reviews...
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Design and implementation of an illumination system to mimic skyglow at ecosystem level in a large‐scale lake enclosure facility
PublicationLight pollution is an environmental stressor of global extent that is growing exponentially in area and intensity. Artificial skyglow, a form of light pollution with large range, is hypothesized to have environmental impact at ecosystem level. However, testing the impact of skyglow at large scales and in a controlled fashion under in situ conditions has remained elusive so far. Here we present the first experimental setup to mimic...
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Physical crosslinking of hyaluronic acid in the presence of phospholipids in an aqueous nano-environment
PublicationHyaluronic acid and phospholipids are two components in the synovial joint cavity that contribute to joint lubrication synergistically. Molecular dynamics simulations were performed and hydrogen bonds in hyaluronic acid were analyzed to identify specific sites that are responsible for its physical cross-linking. Two molecular masses of hyaluronic acid, 10 kDa and 160 kDa, were considered. We use molecular dynamics simulations and...
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C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex
PublicationImidazoacridinone C-1311 (Symadex®) is an antitumor agent which has been recommended for Phase II clinical trials a few years ago. Previously, it was shown experimentally that during the initial stage of its action C-1311 forms stable intercalation complexes with DNA duplexes. Herein, a NMR-derived stereostructure of d(GAGGCCTC)2:C-1311 complex was reported. The ligand was found locating itself between A and G moieties, forming...