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DESIGN THINKING ORIENTED METHODOLOGY IN GROUP PROJECT AS A STEP IN THE CDIO APPROACH
PublicationRecently much scientific research and industrial work is conducted in multidisciplinary teams, where cooperation between specialists from different areas of expertise is required in order to successfully address the challenging goals. Moreover, in start-up small companies the lack of supporting departments calls for additional multidisciplinary, economic and networking skills known as T-shaped personality. Recognizing these shortcomings...
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Dynamic Headspace Sampling as an Initial Step for Sample Preparation in Chromatographic Analysis
PublicationThis work represents a brief summary of the use of dynamic headspace (DHS) as a technique for sample preparation in chromatographic analysis. Despite numerous developments in the area of analyte isolation and enrichment, DHS remains one of the fundamental methods used with GC. In our opinion, interest in this technique will not diminish significantly because it conforms to stipulations of green analytical chemistry. Moreover, DHS...
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Synchronized six-step voltage generation in high-speed PMSM drive
PublicationSynchronized voltage generation has already been considered in the context of pulse width modulation (PWM). References prove that synchronized PWM substantially decreases subharmonics in inverter output voltage when operating with low switching-to-fundamental frequency ratio. This paper identifies problems of unsynchronized voltage generation in electric drives under six-step inverter operation. Guidelines for the synchronization...
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Fermentative Conversion of Two-Step Pre-Treated Lignocellulosic Biomass to Hydrogen
PublicationFermentative hydrogen production via dark fermentation with the application of lignocellulosic biomass requires a multistep pre-treatment procedure, due to the complexed structure of the raw material. Hence, the comparison of the hydrogen productivity potential of different lignocellulosic materials (LCMs) in relation to the lignocellulosic biomass composition is often considered as an interesting field of research. In this study,...
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Two-step mechanism of J-domain action in driving Hsp70 function
PublicationJ-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a recent crystal structure revealed the physical mode of interaction between a J-domain and an Hsp70, the structural and dynamic consequences of J-domain action once bound and how Hsp70s...
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Eco-Friendly Ether and Ester-Urethane Prepolymer: Structure, Processing and Properties
PublicationThis study concerns bio-based urethane prepolymers. The relationship between the chemical structure and the thermal and processing parameters of bio-based isocyanate-terminated ether and ester-urethane prepolymers was investigated. Bio-based prepolymers were obtained with the use of bio-monomers such as bio-based diisocyanate, bio-based polyether polyol or polyester polyols. In addition to their composition, the bio-based prepolymers...
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Hierarchical 2-step neural-based LEGO bricks detection and labeling
PublicationLEGO bricks are extremely popular and allow the creation of almost any type of construction due to multiple shapes available. LEGO building requires however proper brick arrangement, usually done by shape. With over 3700 different LEGO parts this can be troublesome. In this paper, we propose a solution for object detection and annotation on images. The solution is designed as a part of an automated LEGO bricks arrangement. The...
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Step-Up DC/DC Converters With Cascaded Quasi-Z-Source Network
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The Use of Stem Cells as a Potential Treatment Method for Selected Neurodegenerative Diseases: Review
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Nucleotides metabolizing ectoenzymes as possible markers of mesenchymal stem cell osteogenic differentiation
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Human amniotic-fluid-derived stem cells: a unique source for regenerative medicine
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Syntheses, structures and chemical properties of unsaturated oligo(alkylene-ester-ether)diols
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Derivation of continuous explicit two-step Runge-Kutta methods oforder three
PublicationW pracy podana jest konstrukcja ciągłych rozszerzeń dla nowych reprezentacji dwukrokowych metod Rungego-Kutty rzędu trzeciego. Podane zostały metody oceny błędu lokalnego metody oraz opisany został sposób implementacji tych metod dla zmiennego kroku. Przeprowadzono szereg eksperymentów numerycznych pokazujących ich efektywność i konkurencyjność dla programu dde23 z Matlabu.
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Molecularly Imprinted Polymers for Stir Bar Sorptive Extraction: Synthesis, Characterization, and Application
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Femtosecond studies of the excited-state dynamics of ester-alkyloxy substituted zinc phthalocyanines
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Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization
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Assessment of the physical fitness of road cyclists in the step and ramp protocols of the incremental test
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Stability analysis of two-step Runge-Kutta methods for delay differential equations
PublicationW pracy badana jest własność stabilności dwukrokowej metody Rungego-Kutty względem liniowego równania testowego o zespolonych współczynnikach. Udowodniono, że jeśli pewne warunki są spełnione to każda A-stabilna dwukrokowa metoda Rungego-Kutty zastosowana do równania różniczkowego z opóźnieniem jest P-stabilna.
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From chemoresistance to cancer stem cells: the case of BRCP/ABCG2 half transporter
PublicationLudzkie białko ABCG2 jest pompą typu ABC tworzącą homodimery i aktywnie transportującą leki i inne substraty naturalne i syntetyczne. Nadekspresja tego białko prowadzi do oporności na leki przeciwnowotworowe. Białko ABCG2 występuje w wielu formach zmutowanych, różniących się własnościami substratowymi, stąd istotne dla oporności na leki jest jaka forma genu i białka ABCG2 ulega nadekspresji w komórce. Ostatnie badania wskazują,...
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Caffeine Inhibits Differentiation Of Lung Cancer Stem Cells By Modulating Their Respiratory Metabolism
PublicationIt is ell established that many tumor types contain a fraction of cells, with stem cell-like properties, called cancer stem cells (CSCs), that are resistant to apoptosis induced by therapeutic agents. The presence of CSCs may explain why a standard anticancer treatment, that eliminates only differentiated cancer cells, does not lead to cancer cure.We previously showed the existence of caffeine-sensitive mechanism that controls...
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A note on fast approximate backbone coloring of split graphs with star--like backbones
PublicationDla grafu G = (V, E) z wyróżnionym podgrafem H, kolorowanie szkieletowe jest zdefiniowane jako odwzorowanie c spełniające |c(u) - c(v)| > 1 dla każdej krawędzi z E(H) oraz |c(u) - c(v)| > 0 dla każdej krawędzi z E(G). W pracy przedstawiono 1-przybliżony algorytm kolorowania szkieletowego split grafów ze skojarzeniem w szkielecie o złożoności O(|V|) oraz 1-przybliżony algorytm dla split grafów z rozłącznymi gwiazdami w szkielecie.
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Step-Up DC/DC Converters With Cascaded Quasi-Z-Source Network
PublicationW artykule zaprezentowano nowe rozwiązania dotyczące przekształtników energoelektronicznych DC-DC podwyższających napięcie z ogniw paliwowych. Istota rozwiązania zawiera się w zastosowaniu kaskadowo połączonych wejściowych obwodów pasywnych typu Quasi-Z, umozliwiających znaczne podwyższanie napięcia z wykorzystaniem stanu parcy zwarć gałęzi tranzystorowych przekształtnika.
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On the Structure of Time in Computational Semantics of a Variable-Step Solver for Hybrid Behavior Analysis
PublicationHybrid dynamic systems combine continuous and discrete behavior. Often, computational approaches are employed to derive behaviors that approximate the analytic solution. An important part of this is the approximation of differential equation behavior by numerical integration. The accuracy and computational efficiency of the integration usually depend on the complexity of the method and its implicated approximation errors, especially...
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Influence of Osmolytes on Protein and Water Structure: A Step To Understanding the Mechanism of Protein Stabilization
PublicationResults concerning the thermostability of hen egg white lysozyme in aqueous solutions with stabilizing osmolytes, trimethylamine-N-oxide (TMAO), glycine (Gly), and its N-methyl derivatives, N-methylglycine (NMG), N,N-dimethylglycine (DMG), and N,N,N-trimethylglycine (betaine, TMG), have been presented. The combination of spectroscopic (IR) and calorimetric (DSC) data allowed us to establish a link between osmolytes’ influence on...
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Protection of Earthing Reactor Connected to the Star Point of a High Voltage Shunt Reactor
PublicationThe article presents the problem of protection of earthing reactors connected to the star point of shunt reactors in high voltage lines, with particular regard to the detection of internal faults. Model analyses for an actual system commissioned in 2015, which is intended to be provided with earthing reactors, are included.
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The synthesis and structure of a potential immunosuppressant: N-mycophenoyl malonic acid dimethyl ester
PublicationThe synthesis of a potential immunosuppressant, i.e. dimethyl ester of N-mycophenoyl malonic acid was optimized in the reaction of mycophenolic acid (MPA) with amino malonic dimethyl ester in the presence of propanephosphonic anhydride (T3P) as a coupling reagent. The structural properties of the obtained MPA derivative were investigated by NMR, MS and single crystal X-ray diffraction methods. Theoretical considerations of conformational...
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Step on It Bringing Fullwave Finite-Element Microwave Filter Design up to Speed
PublicationThere are many steps in the design of a microwave filter: mathematically describing the filter characteristics, representing the circuit as a network of lumped elements or as a coupling matrix, implementing the distributed elements, finding the initial dimensions of the physical structure, and carrying out numerical tuning using electromagnetic (EM) simulators. The whole process is painstaking and time-consuming, and it requires...
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One-step recovery of REE oxalates in electro-leaching of spent NdFeB magnets
PublicationRecovery of rare-earth elements (REEs) from spent NdFeB magnets is receiving great attention because of high amount of neodymium and potential risk of environmental pollution. In this study, a novel environment-friendly hydrometallurgical route is proposed for efficient recovery of REEs during electrochemical leaching with sulfuric and oxalic acids. With proper adjustment of the electrolyte composition and operating conditions,...
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Water-lubricated stern tube bearing - experimental and theoretical investigations of thermal effects
PublicationThe paper presents research results of thermal phenomena accompanying operation of a water-lubricated stern tube bearing with axial grooves. Experimental tests revealed, that intensity of forced axial flow has strong influence on bush temperature. Numerical simulations focused on investigation of the thermal phenomena under operation of water-lubricated journal bearing showed, that restricted axial flow promotes backflow of the...
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Numerical Analysis of Turbulent Flow over a Backward-facing Step in an Open Channel
PublicationComputational examinations of the flow field in an open channel having a single Backward--Facing Step (BFS) with a constant water depth of 1.5 m were performed. The effects of the expansion ratio, and the flow velocity along the reattachment length, were investigated by employing two different expansion ratios of 1.5 and 2, and eight various flow velocities of 0.5, 1, 2, 3, 4, 5, 7.5 and 10 m/sec in the Computational Fluid Dynamic...
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Selenium enrichment in broccoli sprouts as an initial step in the preparation of Certified Reference Material
PublicationSelenium is considered one of the essential elements in animals and humans. The main source of selenium intake for humans is the diet. Selenium deficiency has one of the most concerning issues worldwide. Broccoli sprouts are five-to-six-day old broccoli plants,...
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Effect of Processing Parameters on Strength and Corrosion Resistance of Friction Stir-Welded AA6082
PublicationThe friction stir welding method is increasingly attracting interest in the railway sector due to its environmental friendliness, low cost, and ease of producing high-quality joints. Using aluminum alloys reduces the weight of structures, increasing their payload and reducing fuel consumption and running costs. The following paper presents studies on the microstructure, strength, and corrosion resistance of AA6082 aluminum alloy...
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Thermo-Mechanical Simulation of Underwater Friction Stir Welding of Low Carbon Steel
PublicationThis article investigates the flow of materials and weld formation during underwater friction stir welding (UFSW) of low carbon steel. A thermo-mechanical model is used to understand the relation between frictional heat phenomena during the welding and weld properties. To better understand the effects of the water environment, the simulation and experimental results were compared with the sample prepared by the traditional friction...
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An experimental and theoretical study of the hetero Diels–Alder reactions between (E)-2-aryl-1-cyano-1-nitroethenes and ethyl vinyl ether: one-step or zwitterionic, two-step mechanism?
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New high-gain step-up DC/DC converter with high-frequency isolation
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How to influence the mesenchymal stem cells fate? Emerging role of ectoenzymes metabolizing nucleotides
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On the interpretation of high-resolution x-ray spectra from JET with an ITER-like wall
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The effect of hard/soft segment composition on radiation stability of poly(ester-urethane)s
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Evaluation of Influence of the Addition Nanofillers on the Mechanical and Thermal Properties Terpolymers Ester-Ether-Amide
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Artificial intelligence-based imaging analysis of stem cells: a systematic scoping review protocol
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approximation of photonic crystal fibres with large air holes by the step index fibre model
PublicationAn equivalent step index fibre with a silica core and air cladding is used to model photonic crystal fibres with large air holes. We model this fibre for linear polarisation (we focus on the lowest few transverse modes of the electromagnetic field). The equivalent step index radius is obtained by equating the lowest two eigenvalues of the model to those calculated numerically for the photonic crystal fibres. The step index parameters...
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a novel modified star-triangular fractal (MSTF) monopole antenna for super-wideband applications
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a novel modified star-triangular fractal (MSTF) monopole antenna for super-wideband applications
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The influence of hard segment crosslinking on the morphology and mechanical properties of segmented poly(ester-urethanes)
PublicationPrównano właściwości i morfologie usieciowanych trójmetylolopropanem (TMP) i nieusieciowanych poliestrouretanów formowanych reaktywnie. W nieusieciowanych poliestrouretanach stwierdzono za pomocą AFM obecność agregacji domen segmentów sztywnych o wymiarze 70-380 nm. W usieciowanych poliuretanach zaobserwowano jedynie jednolicie rozmieszczone domeny segmentów sztywnych wielkości 20 nm. Właściwości mechaniczne wyraźnie różniły się,...
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Surface-Step-Induced Magnetic Anisotropy in Epitaxial LSMO Deposited on Engineered STO Surfaces
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
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Two novel nucleoside ester derivatives of chlorambucil as potential antileukemic prodrugs: a preliminary study
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Effects of Noncontact Shoulder Tool Velocities on Friction Stir Joining of Polyamide 6 (PA6)
PublicationIn this study, the effects of the traverse and rotational velocities of the noncontact shoulder tool on the heat generation and heated flux during the friction stir joining of high-density polyamide 6 (PA6) polymer were investigated. The computational fluid dynamics (CFD) method was employed to simulate the thermomechanical phenomena during the friction stir joining (FSJ) process of PA6. A developed model was used to consider the...
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Influence of friction stir welding technological parameters on the properties of the joints of selected aluminum alloys
PublicationThe purpose of this dissertation was to determine the effect of friction stir welding technological parameters on the properties of selected aluminum alloy joints, with consideration of the residual stresses and dislocation density in the joints. The goal of the present work was also to produce defect-free joints with high mechanical and electrochemical properties. In the dissertation, similar welds of AA6082 alloy and dissimilar...
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TR-Based Antenna Design with Forward FD: The Effects of Step Size on the Optimization Performance
PublicationNumerical methods are important tools for design of modern antennas. Trust-region (TR) methods coupled with data-efficient surrogates based on finite differentiation (FD) represent a popular class of antenna design algorithms. However, TR performance is subject to FD setup, which is normally determined a priori based on rules-of-thumb. In this work, the effect of FD perturbations on the performance of TR-based design is evaluated...