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Search results for: dna sequence recognition
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Krzysztof Goczyła prof. dr hab. inż.
PeopleKrzysztof Goczyła, full professor of Gdańsk University of Technology, computer scientist, a specialist in software engineering, knowledge engineering and databases. He graduated from the Faculty of Electronics Technical University of Gdansk in 1976 with a degree in electronic engineering, specializing in automation. Since then he has been working at Gdańsk University of Technology. In 1982 he obtained a doctorate in computer science...
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Jan Daciuk dr hab. inż.
PeopleJan Daciuk received his M.Sc. from the Faculty of Electronics of Gdansk University of Technology in 1986, and his Ph.D. from the Faculty of Electronics, Telecommunications and Informatics of Gdańsk University of Technology in 1999. He has been working at the Faculty from 1988. His research interests include finite state methods in natural language processing and computational linguistics including speech processing. Dr. Daciuk...
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SiMiSnoRNA: Collection of siRNA, miRNA, and snoRNA database for RNA Interference
PublicationObjective:The discovery of sequence specific gene silencing which occurs due to the presence of double-stranded RNAs has considerable impact on biology, revealing an unknown level of regulation of gene expression. This process is known as RNA interference (RNAi) or RNA silencing in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecule. Two types of small RNA molecules - small...
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Endoscopic Videos Deinterlacing and On-Screen Text and Light Flashes Removal and Its Influence on Image Analysis Algorithms' Efficiency
PublicationIn this article, deinterlacing and removing on- screen text and light flashes methods on endoscopic video images are discussed. The research is intended to improve disease recognition algorithms' performance. In the article, four configurations of deinterlacing methods and another four configurations of text and flashes removal methods are described and examined. The efficiency of endoscopic video analysis algorithms is measured...
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Projektowanie Konstrukcji Okrętu, P, BOiJ, sem7 DS - studia niestacjonarne, zimowy 21/22, (PG_00046546)
e-Learning CoursesWykonanie metodą MES w oprogramowaniu MSC Patran/Nastran 2021.1 Student Edition analizy obciążenia fragmentu sekcji dna podwójnego i pokładu promu pasażersko-samochodowego.
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Możliwości zastosowań, potencjalne źródła oraz ewolucja technologiczna sposobu otrzymywania trehalozy ze szczególnym uwzględnieniem enzymu syntazy trehalozy [EC 5.4.99.16]
PublicationJedna z wiodących gałęzi współczesnej biotechnologii opiera się na produkcji białek – przede wszystkim enzymów. Są one powszechnie wykorzystywane: od przemysłu chemicznego poprzez przemysł spożywczy aż po medycynę i życie codzienne (czy ktoś wyobraża sobie w dzisiejszych czasach proszek do prania „bez enzymu”). Przed rozwojem nowoczesnych metod biologii molekularnej i inżynierii genetycznej pozyskiwano interesujące substancje z...
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Konstrukcja Okrętu II , W, BOiJ, sem 5 - studia niestacjonarne , zimowy 21/22 (PG_00046526)
e-Learning CoursesOgólne zasady konstrukcji kadłubów statkówCz. I Ruszty, odstęp elementów zładu, krzyżowanie się usztywnień, otwory, luzy i naddatki, węzłówkiCz. II Nazwy płatów poszycia, usztywnień i wiązarów elementów kadłubaDna pojedynczegoDna podwójnegoPokładów Burty pojedynczejBurty podwójnejGrodzi i przegródRufyDziobuFundamenty SG, SP oraz innych urządzeńZbiornikówNadbudówki, pokładówki
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Virtual Engineering Objects: Effective Way of Knowledge Representation and Decision Making
PublicationThis paper presents a knowledge representation case study by constructing Decisional DNA of engineering objects. Decisional DNA, as a knowledge representation structure not only offers great possibilities on gathering explicit knowledge of formal decision events but also it is a powerful tool for decision-making process. The concept of Virtual engineering Object (VEO), which is a knowledge and experience representation of engineering...
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An electronic nose for quantitative determination of gas concentrations
PublicationThe practical application of human nose for fragrance recognition is severely limited by the fact that our sense of smell is subjective and gets tired easily. Consequen tly, there is considerable need for an instrument that can be a substitution of the human sense of smell. Electronic nose devices from the mid 1980s are used in growing number of applications. They comprise an array of several electrochemical gas sensors...
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Towards Emotion Acquisition in IT Usability Evaluation Context
PublicationThe paper concerns extension of IT usability studies with automatic analysis of the emotional state of a user. Affect recognition methods and emotion representation models are reviewed and evaluated for applicability in usability testing procedures. Accuracy of emotion recognition, susceptibility to disturbances, independence on human will and interference with usability testing procedures are...
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Data on solutions of Hes1 system
Open Research DataHes1 protein (hairy and enhancer of split 1) belongs to the helix-loop-helix (bHLH) family of transcription proteins, i.e. DNA-binding proteins in the promoter region or in another region where regulation of transcription processes occurs. The database collects data on solutions of the Hes1 systems with multiple binding sites and the dimer formation...
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VOLTAMMETRIC DETERMINATION OF DEOXYRIBONUCLEIC ACID PRESENCE ON A CARBON ELECTRODE
PublicationThis paper presents a voltammetry as a useful method to analyse DNA from different species. This electrochemical method is well know and used in different analyses. The influence of an area of working electrode and the capacity component, is shown at equals and the measurement. In voltammetry DNA measurement the capacity component is very important and must be taken into consideration. All mathematical analyses were verify at laboratory.
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Computing dynamical curlicues
Open Research DataA curlicue is a piece-wise linear curve in the complex plane which can be generated by an arbitrary sequence of real numbers u_n. It can be interpreted as a trajectory of a particle in the plane which starts in the origin at time t=0 and moves with a constant velocity, changing its direction at instances t=0,1,2,3,..., where the new direction is given...
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Novel primosomal protein B from Clostridium pasteurianum
PublicationPriB is a primosomal protein that catalyzes DNA replication in Procaryota. The replication pathway starts with PriA protein - the initiator protein that binds to a DNA replication fork, unwinds double-stranded DNA and role of PriB is to stabilize PriA on the DNA. However there are many biochemical differences in replication mechanism in bacteria and only some of them use PriB proteins. A few of PriB proteins were published and...
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Novel primosomal protein B from Clostridium pastuerianum
PublicationPriB is a primosomal protein that catalyzes DNA replication in Procaryota. The replication pathway starts with PriA protein - the initiator protein that binds to a DNA replication fork, unwinds double-stranded DNA and role of PriB is to stabilize PriA on the DNA. However there are many biochemical differences in replication mechanism in bacteria and only some of them use PriB proteins. A few of PriB proteins were published and...
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Wiązanie się do DNA pochodnych 4-metylo-1-nitroakrydyny wykazujących właś-ciwości przeciwnowotworowe.**2003, 116 s. 23 rys. 12 tab. bibliogr. 163 poz. maszyn. Rozprawa doktorska /09.05.2003/ P. Gdań. Wydz. Chem. Promotor: prof. dr hab. inż. J. Konopa.
Publication.
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Enhanced voice user interface employing spatial filtration of signals from acoustic vector sensor
PublicationSpatial filtration of sound is introduced to enhance speech recognition accuracy in noisy conditions. An acoustic vector sensor (AVS) is employed. The signals from the AVS probe are processed in order to attenuate the surrounding noise. As a result the signal to noise ratio is increased. An experiment is featured in which speech signals are disturbed by babble noise. The signals before and after spatial filtration are processed...
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Real-Time PCR: molecular technique of many applications
PublicationReal-Time PCR is a sensitive DNA amplification technique initially applied in genetics and molecular biology. It enables in vivo copying of the selected DNA fragment (flanked by two primers) by the thermostable polymerase (in the presence of magnesium ions and deoxynucleotide triphosphates) and simultaneous measurement of the fluorescence. For one or more specific sequences in a DNA sample, real-time PCR enables both detection...
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Video Semantic Analysis Framework based on Run-time Production Rules - Towards Cognitive Vision
PublicationThis paper proposes a service-oriented architecture for video analysis which separates object detection from event recognition. Our aim is to introduce new tools to be considered in the pathway towards Cognitive Vision as a support for classical Computer Vision techniques that have been broadly used by the scientific community. In the article, we particularly focus in solving some of the reported scalability issues found in current...
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KORPUS MOWY ANGIELSKIEJ DO CELÓW MULTIMODALNEGO AUTOMATYCZNEGO ROZPOZNAWANIA MOWY
PublicationW referacie zaprezentowano audiowizualny korpus mowy zawierający 31 godzin nagrań mowy w języku angielskim. Korpus dedykowany jest do celów automatycznego audiowizualnego rozpoznawania mowy. Korpus zawiera nagrania wideo pochodzące z szybkoklatkowej kamery stereowizyjnej oraz dźwięk zarejestrowany przez matrycę mikrofonową i mikrofon komputera przenośnego. Dzięki uwzględnieniu nagrań zarejestrowanych w warunkach szumowych korpus...
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On the existence of homoclinic type solutions of inhomogenous Lagrangian systems
PublicationWe study the existence of homoclinic type solutions for a class of inhomogenous Lagrangian systems with a potential satisfying the Ambrosetti-Rabinowitz superquadratic growth condition and a square integrable forcing term. A homoclinic type solution is obtained as a limit of periodic solutions of an approximative sequence of second order differential equations.
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Diagnostyka molekularna w medycynie 2023
e-Learning CoursesCelem przedmiotu jest zapoznanie studenta z nowoczesnymi, molekularnymi metodami stosowanymi w diagnostyce medycznej oraz nabycie umiejętności posługiwania się programami do obróbki danych z poziomu DNA.
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Spectroelectroanalytical properties of antitumor agent C1311
PublicationZastosowano kilka metod woltamperometrycznych dla charakterystyki właściwości elektrochemicznych przeciwnowotworowej pochodnej imidazoakrydonu o symbolu C-1311. Wyniki wskazały, że możliwym będzie zastosowanie metod elektrochemicznych do badania oddziaływań badanego związku z DNA. Badania spektroelektrochemiczne ujawniły, że oscylacyjne zmiany absorbcji związku obserwowane po cyklicznej polaryzacji elektrody. Oscylacje te znikały...
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In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections
PublicationWe presented in vitro studies of antimicrobial activity of Gly-His-Lys conjugates that are important point in preliminary biological evaluation of their potential application in skin and tissue therapy. The novel compounds include the conjugation of fatty acids with a modification of the amino acid sequence in the primary structure of Gly-His-Lys.
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Geometric Algebra Model of Distributed Representations
PublicationFormalism based on GA is an alternative to distributed representation models developed so far-Smolensky's tensor product, Holographic Reduced Representations (HRR) and Binary Spatter Code (BSC). Convolutions are replaced by geometric products, interpretable in terms of geometry which seems to be the most natural language for visualization of higher concepts. This paper recalls the main ideas behind the GA model and investigates...
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The project IDENT: Multimodal biometric system for bank client identity verification
PublicationBiometric identity verification methods are implemented inside a real banking environment comprising: dynamic handwritten signature verification, face recognition, bank cli-ent voice recognition and hand vein distribution verification. A secure communication system based on an intra-bank client-server architecture was designed for this purpose. Hitherto achieved progress within the project is reported in this paper with a focus...
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Instalacja i wstępna analiza danych batymetrycznych pochodzących z echosondy wielowiązkowej
PublicationW akustycznym telemonitoringu środowiska morskiego stosowane są dwa rodzaje sonarów, a mianowicie: sonary boczne i echosondy wielowiązkowe. Oba systemy dostarczają danych zarówno dla batymetrii, jak i dla akustycznego obrazowania dna morskiego. Echosondy wielowiązkowe są zaawansowanymi technologicznie urządzeniami, które dzięki wielokierunkowej obserwacji szerokokątnej dna, przy jednoczesnym utrzymaniu wysokiej rozdzielczości kątowej,...
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MutL protein as a constituent of vsp, ner and mmr repair systems
PublicationMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mis- match repair system (MMR). However, there is growing evidence that MMR system is not the only field of action for these pro- teins. Moreover, the participation in MMR does not even have to be their primary function. There are some reports indicat- ing involvement of MutL in BER, NER and VSP (very short patch repair)....
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MUTL PROTEIN AS A COMMON CONSTITUENT OF VSP, BER, NER AND MMR REPAIR SYSTEMS
PublicationMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mismatch repair system (MMR). However, there is growing evidence that MMR system is not the only field of action of these proteins. Moreover, involvement in MMR does not even have to be their primary function. There are some reports indicating involvement of MutL in BER, NER and VSP (very short patch repair). MutL protein...
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The role of epigenetics in regeneration
PublicationComplex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...
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Discrimination of hospital isolates of Acinetobacter baumannii using repeated sequences and whole genome alignment differential analysis
PublicationAn optimized method for bacterial strain differentiation, based on combination of Repeated Sequences and Whole Genome Alignment Differential Analysis (RS&WGADA), is presented in this report. In this analysis, 51 Acinetobacter baumannii multidrug-resistance strains from one hospital environment and patients from 14 hospital wards were classified on the basis of polymorphisms of repeated sequences located in CRISPR region, variation...
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Adaptive neuro fuzzy and fuzzy decision tree classifiers as applied to sea floor characterization.
PublicationPrzedstawiono wyniki badań wpływu różnych parametrów echa odbitego od dna morskiego na dokładność klasyfikacji typu dna przy pomocy sieci neuronowej z logiką rozmytą i przy pomocy drzew decyzyjnych. W szczególności uwzględniono takie parametry echa jak: energia, amplituda i nachylenie opadającego zbocza, wzbogacone o współczynniki falkowe otrzymane z dyskretnej transformacji falkowej (DWT).
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DevEmo—Software Developers’ Facial Expression Dataset
PublicationThe COVID-19 pandemic has increased the relevance of remote activities and digital tools for education, work, and other aspects of daily life. This reality has highlighted the need for emotion recognition technology to better understand the emotions of computer users and provide support in remote environments. Emotion recognition can play a critical role in improving the remote experience and ensuring that individuals are able...
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Methodology for Text Classification using Manually Created Corpora-based Sentiment Dictionary
PublicationThis paper presents the methodology of Textual Content Classification, which is based on a combination of algorithms: preliminary formation of a contextual framework for the texts in particular problem area; manual creation of the Hierarchical Sentiment Dictionary (HSD) on the basis of a topically-oriented Corpus; tonality texts recognition via using HSD for analysing the documents as a collection of topically completed fragments...
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Magdalena Szuflita-Żurawska
PeopleHead of the Scientific and Technical Information Services at the Gdansk University of Technology Library and the Leader of the Open Science Competence Center. She is also a Plenipotentiary of the Rector of the Gdańsk University of Technology for open science. She is a PhD Candidate. Her main areas of research and interests include research productivity, motivation, management of HEs, Open Access, Open Research Data, information...
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Two-state dynamics for replicating two-strand systems
PublicationDynamika dwustanowa została zastosowana do opisów układów dwuniciowych, analogicznych do DNA.
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Homocitrate synthase gene as a new molecular target in diagnostics of Candida spp. infections
PublicationNew potential molecular target which will be investigated during this research (homocitrate synthase gen) is the innovative target other than ribosomal DNA. This gene encodes enzyme present only in fungi and some Archaea what significantly increases specificity. It also reduces risk of contamination or influence of other factors (reaction with other DNA present in sample derived from bacteria or host cells) what excludes false...
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System do diagnostyki dermatofitowych zakażeń powierzchniowych oparty na technice Real-Time PCR
PublicationDermatofity należą do blisko spokrewnionej grupy grzybów, które wykazują wysokie powinowactwo do skeratynizowanych tkanek. Cecha ta czyni je odpowiedzialnymi za powierzchniowe grzybice skóry, paznokci oraz włosów. Szacuje się, iż nawet do 20% ludzi na całym świecie dotkniętych jest infekcjami powodowanymi przez dermatofity. Ich leczenie wymaga długotrwałego zastosowania leków przeciwgrzybiczych. W celu dobrania odpowiedniego leczenia...
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Structural changes of a simple peptide—Trpzip-1—in aqueous solutions and the corresponding hydration phenomena under the influence of temperature
PublicationTrpzip-1, a simple β-hairpin, is a rare example of peptide with stable secondary structure and can be a convenient model to study temperature-related processes that potential prion or amyloid proteins undergo. Although its sequence is simple, the exact processes which the peptide undergoes in aqueous solutions are quite complex and not well understood. The selection of well-established experimental (DSC, FTIR) and theoretical methods...
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Artificial intelligence support for disease detection in wireless capsule endoscopy images of human large bowel
PublicationIn the work the chosen algorithms of disease recognition in endoscopy images were described and compared for theirs efficiency. The algorithms were estimated with regard to utility for application in computer system's support for digestive system's diagnostics. Estimations were achieved in an advanced testing environment, which was built with use of the large collection of endoscopy movies received from Medical University in Gdańsk....
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Sensors integration in the smart home environment - a proposal to solve the problem with user identification
PublicationIn this preliminary study we, investigate the possibility of user recognition techniques suitable on smart home devices like chairs, beds, aiming for low–power, high accuracy and quick response time. We propose the two well know technique: voice speaker recognition and accelerometer signal from device mounted on the chair, and the third one optical system basing on IR LED transmitter/receiver circuit. The preliminary results proved...
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Evaluation and cellular responses of modulators of TRF1/TRF2 protein’s function as potential anticancer drugs interfering with telomeric shelterin’s function
PublicationA number of proteins that interact with telomeres have been identified in human cells, indicating the high plasticity of human nucleoprotein complex organization. The most important complex is the "shelterin" complex, which consists of six proteins: TRF1, TRF2, TIN2, POT1, TPP1. The TRF1 and TRF2 directly bind to telomeric double-stranded DNA and the TIN2 protein. The TIN2 protein also binds to the TPP1 protein, stabilizing the...
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Selected results of the parametric sounding of the Gdansk Bay
PublicationW pracy przedstawiono metodykę i wyniki sondowania dna Zatoki Gdańskiej echosondą parametryczną.
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NASBA – IZOTERMICZNA AMPLIFIKACJA RNA
PublicationNASBA (ang. Nucleic Acid Sequence-Based Amplification) jest skuteczną i czułą techniką izotermicznej amplifikacji opartej na transkrypcji, służąca głównie do detekcji cząsteczek RNA. Znalazła ona zastosowanie do wykrywania RNA wirusowego, bakteryjnego i grzybiczego w próbkach klinicznych oraz żywości.
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Experience Based Clinical Decision Support Systems: An Overview and Case Studies
PublicationThis chapter briefly overviews the evolution of the application of the Decisional DNA and the Set of Experience Knowledge Structure (SOEKS) in the medical domain and in particular in the specific case of the experience-based decision support systems. Decisional DNA, as a knowledge representation structure, offers great possibilities on gathering explicit knowledge of formal decision events as well as a tool for decision making...
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Phenotypic and genotypic identification of atypical L. monocytogenes
Open Research DataThe data represent the results of research within the Miniatura 5 scientific activity entitled "Characterization of atypical Listeria monocytogenes strains isolated from the food production environment financed by the National Science Center (no. DEC 2021/05/X/NZ9/00143). The aim of this part of the project was (i) to learn about the differences between...
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Dagmara Lisman PhD
PeopleScientist, biologist, forensic geneticist. She completed her master's studies at the West Pomeranian University of Technology in Szczecin, at the Faculty of Biology, and obtained a doctoral degree in forensic genetics at the Pomeranian Medical University in Szczecin. Currently, he works as an assistant at the Department of Forensic Medicine of the same university. Her research, conducted at the Department of Forensic Genetics at...
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Remote Sensing in Vessel Detection and Navigation
PublicationThe Special Issue (SI) “Remote Sensing in Vessel Detection and Navigation” highlighted a variety of topics related to remote sensing with navigational sensors. The sequence of articles included in this Special Issue is in line with the latest scientific trends. The latest developments in science, including artificial intelligence, were used. The 15 papers (from 23 submitted) were published.
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Immunological response of sheep to injections of plasmids encoding Toxoplasma gondii SAG1 and ROP1 genes
PublicationInfection with the intracellular protozoan parasite Toxo¬plasma gondii (T. gondii) causes health problems to both humans and livestock and has a large economic impact worldwide. The immune response in sheep following infection with T. gondii was evaluated using six different combinations of plasmid DNA, recombinant antigen and adjuvant. Sheep were generally vaccinated twice by intramuscular injection with plasmid DNA containing...
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The Toolbox of Methods for Multidirectional Characterization of Dietary Nucleic Acids; Verification for Raw and Processed Food Products
PublicationCurrently, the nutritional value of food is associated mainly with components such as proteins, carbohydrates, and lipids. However, another important macromolecules present in many foods are dietary nucleic acids (dietNA), i.e., DNA as well as both coding and non-coding RNAs. In the context of food chemistry and nutrition, dietNA are nowadays vastly neglected. In consequence, there are no dedicated methodologies to characterize...