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Dissociative Electron Attachment to 5-Iodo-4-thio-2′-deoxyuridine: A Potential Radiosensitizer of Hypoxic Cells
PublicationIn the search for effective radiosensitizers for tumor cells, halogenated uracils have attracted more attention due to their large cross section for dissociation upon the attachment of low-energy electrons. In this study, we investigated dissociative electron attachment (DEA) to 5-iodo-4-thio-2'-deoxyuridine, a potential radiosensitizer using a crossed electron-molecule beam experiment coupled with quadrupole mass spectrometry....
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Review of Cybersecurity Assessment Methods: Applicability Perspective
PublicationCybersecurity assessments are crucial in building the assurance that vital cyberassets are effectively protected from threats. Multiple assessment methods have been proposed during the decades of the cybersecurity field. However, a systematic literature search described in this paper reveals that their reviews are practically missing. Thus, the primary objective of this research was to fulfil this gap by comprehensively identifying...
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Improving css-KNN Classification Performance by Shifts in Training Data
PublicationThis paper presents a new approach to improve the performance of a css-k-NN classifier for categorization of text documents. The css-k-NN classifier (i.e., a threshold-based variation of a standard k-NN classifier we proposed in [1]) is a lazy-learning instance-based classifier. It does not have parameters associated with features and/or classes of objects, that would be optimized during off-line learning. In this paper we propose...
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Kombucha from alternative raw materials – The review
PublicationNowadays, people's awareness about the role of diet in maintaining well-being and good health has increased. Consumers expect that the products not only provide them with essential nutrients but will also be a source of biologically active substances, which are beneficial to their health. One of the "healthy trends," which has appeared among the consumers worldwide is kombucha, a tea drink with high antioxidant potential, obtained...
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Proposed method for estimating the costs of safety barrier life cycle
PublicationToday barrier types are frequently selected for their price with little regard for the total costs the structure will incur over its lifetime. One of the basic tools designed to manage road infrastructure is the life cycle cost method (LCC, Life cycle cost). It sums up the costs to plan, design, build, operate (use and maintain) and decommission a road structure. Having developed dynamically at the turn of the century the method...
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The Ellenbogen’s “Matter as Software” Concept for Quantum Computer Implementation: IV. The X@C60 Molecular Building Blocks (MBBs) and Computing System Lifetime Estimation
PublicationThe problem of approximate lifetimes of individual X@C60 MBBs and tip-based nanofabricated quantum computing device systems is discussed under the conservative assumption of single-point failure. A single chemical transformation of the C60 cage into high-energy opened o-C60 isomer which forms the communication canal for the low energy transfer of an X atom from X@C60 MBB to the outside environment was studied. According to the...
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Swarm-Assisted Investment Planning of a Bioethanol Plant
PublicationBioethanol is a liquid fuel for which a significant increase in the share of energy sources has been observed in the economies of many countries. The most significant factor in popularizing bioethanol is the profitability of investments in construction of facilities producing this energy source, as well as the profitability of its supply chain. With the market filled with a large amount of equipment used in the bioethanol production...
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Issues related to noise and protection against noise against the background of hazards present in the working environment
PublicationNoise is one of the physical factors that poses the greatest threat in the working environment. In order to reduce the noise exposure, noise reduction at the source should be considered. Next, the engineering and administrative controls are being developed. Finally, hearing protectors are used. Issues related to protection against noise are part of the topics in the field of occupational...
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Determinants of export diversification: an empirical investigation
PublicationEmpirical findings confirm that relatively high specialisation of economic structures tends to be associated with low levels of income per capita, but countries diversify their export structures along their path of growth. However, usually only per capita income, and eventually, country-specific fixed effects are the sole explanatory variables taken into consideration in the estimation of specialisation curves. We extend the analysis...
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E-Technologies in Teaching Research Methodology for Engineers – a Case Study of the Course for International Postgraduate Students
PublicationThe Research Methodology course for postgraduate students is challenging, even for an experienced academic teacher. The primary objective of this course is to prepare participants to conduct scientific research and publish the results. This case study presents an original teaching method applied to Research Methodology with Emphasis on Engineering Science, for international engineering students at...
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An Application Supporting Gastroesophageal Multichannel Intraluminal Impedance-pH Analysis
PublicationDue to a significant rise in the number of patients diagnosed with diseases of the upper gastrointestinal tract and the high cost of treatment, there is a need to further research on one of the most popular diagnostic tests used in this case – esophageal Multichannel Intraluminal Impedance and pH measurement. This may lead to finding new diagnostically relevant information, used to quicken and improve the diagnostic procedure....
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Cost-Efficient Design Methodology for Compact Rat-Race Couplers
PublicationIn this article, a reliable and low-cost design methodology for simulation-driven optimization of miniaturized rat-race couplers (RRCs) is presented. We exploit a two-stage design approach, where a composite structure (a basic building block of the RRC structure) is first optimized using a pattern search algorithm, and, subsequently, the entire coupler is tuned by means of surrogate-based optimization (SBO) procedure. SBO is executed...
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Controlled Random Search Applied to Parameters Estimation of the Longitudinal Solutes Transport Model for Rivers
PublicationNumerical computations are presented for the longitudinal transport of passive, conservative solutes in an actual river with the inclusion of geometrical complexities of river channels. A special emphasis is put on the method of the identification of model parameters which is based on a specially designed optimisation procedure using random control search algorithm. Two different situations are considered namely a linear version...
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Expedited Gradient-Based Design Closure of Antennas Using Variable-Resolution Simulations and Sparse Sensitivity Updates
PublicationNumerical optimization has been playing an increasingly important role in the design of contemporary antenna systems. Due to the shortage of design-ready theoretical models, optimization is mainly based on electromagnetic (EM) analysis, which tends to be costly. Numerous techniques have evolved to abate this cost, including surrogate-assisted frameworks for global optimization, or sparse sensitivity updates for speeding up local...
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On EM-driven size reduction of antenna structures with explicit constraint handling
PublicationSimulation-driven miniaturization of antenna components is a challenging task mainly due to the presence of expensive constraints, evaluation of which involves full-wave electromagnetic (EM) analysis. The recommended approach is implicit constraint handling using penalty functions, which, however, requires a meticulous selection of penalty coefficients, instrumental in ensuring optimization process reliability. This paper proposes...
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Towards Computer-Aided Graphene Covered TiO2-Cu/(CuxOy) Composite Design for the Purpose of Photoinduced Hydrogen Evolution
PublicationIn search a hydrogen source, we synthesized TiO2-Cu-graphene composite photocatalyst for hydrogen evolution. The catalyst is a new and unique material as it consists of copper-decorated TiO2 particles covered tightly in graphene and obtained in a fluidized bed reactor. Both, reduction of copper from Cu(CH3COO) at the surface of TiO2 particles and covering of TiO2-Cu in graphene thin layer by Chemical Vapour Deposition (CVD) were...
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Buck-Boost Inverters with Symmetrical Passive Four-terminal Networks
PublicationAlternating Voltage Inverters (Converters) supplied by low-voltage sources DC (ex. fuel cell, photovoltaic cell) are most frequently realized on the basis of the three fundamental topologies: a) PWM voltage inverter with boost-converter" system, b) PWM voltage inverter with transformed converter DC/DC in the ,,boost-converter" system, c) PWM current converter. However none of these solutions is claimed to be the best and dominant...
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Increasing K-Means Clustering Algorithm Effectivity for Using in Source Code Plagiarism Detection
PublicationThe problem of plagiarism is becoming increasingly more significant with the growth of Internet technologies and the availability of information resources. Many tools have been successfully developed to detect plagiarisms in textual documents, but the situation is more complicated in the field of plagiarism of source codes, where the problem is equally serious. At present, there are no complex tools available to detect plagiarism...
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Bionic relations as features of the author’s original concept of biomorphic plastic forms that belong to a place
PublicationThe article concerns the search for an architectural formula for living organically in the area of Pojezierze Kaszubskie [the Kashubian Lake Dis- trict]. The original project consisted in creating a series of biomorphic plastic forms that belong to the place. In this way, a set of alternative solutions was created in the form of small clay sculptures that account for bionic relationships between the newly created cultural elements...
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Phage Therapy—Challenges, Opportunities and Future Prospects
PublicationThe increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly. Phages that selectively infect and kill bacteria are often the only life-saving therapeutic option. Full legalization of this treatment method could help solve the problem of multidrug-resistant infectious diseases on a global scale. The aim of...
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Overview of new product development strategies and models
PublicationMotivation: The motivation for the overview presented in this article is to provide a starting point for considering whether existing new product development methodology and its level of detail allows product teams to develop high-quality and business-effective product concepts. Aim: The aim of this article is recognise the current state of research into new product development methodology and to present the strategies and models...
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Floodsar: Automatic mapping of river flooding extent from multitemporal SAR imagery
PublicationFloodsar is an open-source tool for automatic mapping of the flood extent from a time series of synthetic aperture radar (SAR) imagery. Floodsar is unsupervised, however, it requires defining the parameters search space, geographical area of interest, and some river gauge observations (e.g. water levels or discharges) time series that overlap temporarily with the SAR imagery. Applications of Floodsar are mainly in real-time monitoring...
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Effective Drug Concentration and Selectivity Depends on Fraction of Primitive Cells
PublicationPoor efficiency of chemotherapeutics in the eradication of Cancer Stem Cells (CSCs) has been driving the search for more active and specific compounds. In this work, we show how cell density-dependent stage culture profiles can be used in drug development workflows to achieve more robust drug activity (IC50 and EC50) results. Using flow cytometry and light microscopy, we characterized the cytological stage profiles of the HL-60-,...
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Kriging metamodels and design re‐utilization for fast parameter tuning of antenna structures
PublicationThe paper addresses the problem of computationally efficient electromagnetic (EM)‐driven design closure of antenna structures. The foundations of the presented approach are fast kriging interpolation metamodels, utilized for two purposes: (a) producing a good starting point for further parameter tuning, and (b) yielding a reasonable Jacobian matrix estimate to jump‐start the optimization procedure. The models are rendered using...
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Time reversal invariant single-gap superconductivity with upper critical field larger than the Pauli limit in NbIr2B2
PublicationRecently, compounds with noncentrosymmetric crystal structure have attracted much attention for providing a rich playground in search for unconventional superconductivity. NbIr2B2 is a new member to this class of materials harboring superconductivity below Tc = 7.3(2) K and a very high upper critical field that exceeds Pauli limit. Here we report on muon spin rotation (μSR) experiments probing the temperature and field dependence...
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Follow the Light. Where to search for useful research information
PublicationArchitectural Lighting Design (ALD) has never been a standalone professional discipline. Rather, it has existed as the combination of art and the science of light. Today, third generation lighting professionals are already creatively intertwining these fields, and the acceleration in scientific, technological and societal studies has only increased the need for reliable multidisciplinary information. Therefore, a thorough re-examination...
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Path-based methods on categorical structures for conceptual representation of wikipedia articles
PublicationMachine learning algorithms applied to text categorization mostly employ the Bag of Words (BoW) representation to describe the content of the documents. This method has been successfully used in many applications, but it is known to have several limitations. One way of improving text representation is usage of Wikipedia as the lexical knowledge base – an approach that has already shown promising results in many research studies....
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Experimental Investigations of Fracture Process Using DIC in Plain and Reinforced Concrete Beams under Bending
PublicationThe fracture behaviour of concrete and reinforced concrete beams under quasi-static three-point bending was comprehensively investigated with experiments at laboratory scale. The eight various concrete mixes were tested. The influence of the shape, volume and size of aggregate particles and reinforcement on concrete fracture under bending was studied. Displacements on the surface of concrete beams were measured by means of the...
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Technical Engine for Democratization of Modeling, Simulations, and Predictions
PublicationComputational science and engineering play a critical role in advancing both research and daily-life challenges across almost every discipline. As a society, we apply search engines, social media, and se- lected aspects of engineering to improve personal and professional growth. Recently, leveraging such aspects as behavioral model analysis, simulation, big data extraction, and human computation is gain- ing momentum. The nexus...
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Transformation of the countryside into an open-air museum as a way to rescure its spatial layout and to improve the quality of live = Przekształcenie wsi w muzeum na wolnym powietrzu jako sposób ratowania jej układu przestrzennego i poprawy jakości życia mieszkańców
PublicationSince the first open-air museums until today, the exposition subject-matter has been specialized (ethnographic, archeological, industrial and technical skansens). But idea of the existence of such objects remains unchanged. Still, the goal is to show the collection of wooden buildings in the environment as close to their origin as possible or in the home environment. These distinguish the skansens and make them different then municipal...
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Selected symmetrically substituted carbazoles: Investigation of anticancer activity and mechanisms of action at the cellular and molecular levels
PublicationDNA topoisomerases play a critical role as essential enzymes in controlling alterations in the topology of DNA. They achieve this by orchestrating the coordinated process of breaking and rejoining DNA strands, which is crucial for maintaining the proper structure of DNA during regular cellular development. The search for and development of new potential anticancer drugs is a challenging yet immensely important area of research...
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Expedited simulation-driven design optimization of UWB antennas by means of response features
PublicationIn this work, a method for fast design optimization of broadband antennas is considered. The approach is based on a feature-based optimization (FBO) concept where reflection characteristics of the structure at hand are formulated in terms of suitably defined feature points. Redefinition of the design problem allows for reducing the design optimization cost, because the dependence of feature point coordinates on antenna dimensions...
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Using Minimum Actuators to Control Shape and Stress of a Double Layer Spherical Model Under Gravity and Lateral Loadings
PublicationSpherical domes are picturesque structures built in developed countries to attract tourists. Due to horizontal and vertical overloading, the structures’ attractive shapes may be disturbed, and some members' stress may exceed the elastic level. In this paper, the shape and stress of a deformed double-layer spherical numerical model due to simultaneous lateral and vertical loadings are controlled, meanwhile, the number of actuators...
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Mean Crossover in evolutionary path planning method for maritime collision avoidance
PublicationAbstract: This paper presents the use of mean crossover genetic operator for path planning using evolutionary algorithm for collision avoidance on sea. Mean crossover ensures widening of the possible solutions' set that can be achieved in comparison to exchange crossover variant. The research shown, that the mean crossover allows to achieve results independent from the initial generation and quicker transition of thealgorithm from...
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Using Long-Short term Memory networks with Genetic Algorithm to predict engine condition
PublicationPredictive maintenance (PdM) is a type of approach for maintenance processes, allowing maintenance actions to be managed depending on the machine's current condition. Maintenance is therefore carried out before failures occur. The approach doesn’t only help avoid abrupt failures but also helps lower maintenance cost and provides possibilities to manufacturers to manage maintenance budgets in a more efficient way. A new deep neural...
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Complex Corrosion Monitoring System for Crude Distillation Unit in Form of Neutral Network
PublicationComplex and successful corrosion monitoring of refinery processes can significantly reduce material losses and failure risk. The developed corrosion monitoring system is based on online ultrasonic sensors, ER (electrical resistance) probes, gravimetric method and multipoint analytical analysis of chemical composition of the fluids. Additional online LPR (linear polarization resistance) sensors controlling corrosiveness of sour...
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ARRIERE-GARDE IN ARCHITECTURE, AS A RESPONSE TO POST-POSTMODERN REALITY
PublicationThe article presents a general discussion on the direction of contemporary architecture. We can freely speak that postmodernity, understood in its philosophical core as a search for meaning in architecture, as a strategy of building our environment is over. What comes next? Some say, from lack of better naming, that we live in post-postmodern times. Term post-postmodernity is a call for new strategy of shaping our societies and...
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Usage of parametric echosounder with emphasis on buried object searching.
PublicationThe purpose of this article is to present the results of investigation to search for buried objects. The paper will contain echograms and other means of visualization from buried pipe placed between area of W?adys?awowo and gas platform and interesting in terms of the number of small and medium-sized unidentified objects found in the muddy bottom at different depths localized in the Gulf of Puck - results will be presented also...
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The influence of feed rate and shear forces on the devulcanization process of ground tire rubber (GTR) conducted in a co-rotating twin screw extruder
PublicationThe search for new ways to recycling of rubber waste has been the aim of many studies conducted by research centers and companiesworldwide. The results of our investigations on the process of continuous thermomechanical devulcanization of ground tire rubber using a twin screw extruder are presented.We used a co-rotating twin screw extruder with a special configuration of plasticizing unit, enabling generation of considerable shear...
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Investigation of the antimicrobial potential and microbiota of bee pollen and bee bread derived from Polish apiaries
PublicationThe phenomenon of resistance of microorganisms to antibiotics is becoming one of the greatest challenges of modern medicine. At the same time, the number of new antibiotics introduced into clinical practice is decreasing. This creates the need to search for new, effective, non-antibiotic methods of combating and preventing infectious diseases. Over the last two decades, there has been renewed interest in the antimicrobial potential...
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Strategy towards the use of ultrafiltration and reverse osmosis for industrial water recovery and reuse as part of the Green Deal Implementation
PublicationIn line with the European Parliament’s Resolution of February 10th, 2021 on the new action plan for a closed economy, most of the activities undertaken in the wastewater treatment process should focus on the search for new technologies that use wastewater as a source of water and nutrients. The paper reviews the concept of water reuse in industrial installations, with special emphasis on the use of membrane technologies for this...
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A Tabu Search Algorithm for Optimization of Survivable Overlay Computing Systems
PublicationParadygmat obliczeń rozproszonych ostatnio zyskuje coraz większą uwagę, ponieważ zarówno instytucje przemysłowe, jak i uczelnie wymagają coraz większej mocy obliczeniowej do przetwarzania i analizy danych. Z uwagi na dużą podatność systemów obliczeń na awarie różnych typów (podobnie do systemów sieciowych), gwarancje przeżywalności niniejszych systemów są nieodzowne w celu zapewnienia nieprzerwanego działania usług. Z tego powodu,...
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Evolutionary Sets of Safe Ship Trajectories Within Traffic Separation Schemes
PublicationThe paper presents the continuation of the author's research on Evolutionary Sets of Safe Ship Trajectories (ESoSST) methodology. In an earlier paper (Szlapczynski, 2011) the author described the foundations of this methodology, which used Evolutionary Algorithms (EA) to search for an optimal set of safe trajectories for all the ships involved in an encounter. The methodology was originally designed for open waters or restricted...
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Brain-computer interaction based on EEG signal and gaze-tracking information = Analiza interackji mózg-komputer wykorzystująca sygnał EEg i informacje z systemu śledzenia punktu fiksacji wzroku
PublicationThe article presents an attempt to integrate EEG signal analysis with information about human visual activities, i.e. gaze fixation point. The results from gaze-tracking-based measurement were combined with the standard EEG analysis. A search for correlation between the brain activity and the region of the screen observed by the user was performed. The preliminary stage of the study consists in electrooculography (EOG) signal processing....
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Computationally-efficient design optimisation of antennas by accelerated gradient search with sensitivity and design change monitoring
PublicationElectromagnetic (EM) simulation tools are of primary importance in the design of contemporary antennas. The necessity of accurate performance evaluation of complex structures is a reason why the final tuning of antenna dimensions, aimed at improvement of electrical and field characteristics, needs to be based on EM analysis. Design automation is highly desirable and can be achieved by coupling EM solvers with numerical optimisation...
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Selection of circuit geometry for miniaturized microwave components based on concurrent optimization of performance and layout area
PublicationThe paper presents a framework for automated EM-driven circuit geometry selection of miniaturized microwave components. Selection of a particular layout is based directly on miniaturization rates achieved for a set of candidate circuit geometries. Size reduction of the considered structures is obtained by replacing their main building blocks (i.e., conventional transmission lines) with slow-wave composite cells and meander lines....
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Cross sections for electron collision with pyridine [C5H5N] molecule
PublicationThe absolute grand -total cross section (TCS) for electron scattering from pyridine, C5H5N, molecules has been measured at impact energies from 0.6 to 300 eV in the linear electron-transmission experiment. The obtained TCS energy dependence appears to be typical for targets of high electric-dipole moment; the cross section generally decreases with rising energy, except for the 3–20 eV range, where a broad enhancement peaked near...
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Management of low-temperature heat source by ORC aided by additional heat source
PublicationThe presented work is aimed at utilisation of waste heat in the manner to produce electricity in ORC installation. Therefore the precondition of the study was to use the waste heat available in the form of a stream of hot water at 90°C. Such low enthalpy heat source is rather insufficient to produce a good quality vapour to feed the ORC turbine. That was the incentive to search for the ways of increasing the temperature of the...
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A System for Heart Sounds Classification
PublicationThe future of quick and efficient disease diagnosis lays in the development of reliable non-invasive methods. As for the cardiac diseases – one of the major causes of death around the globe – a concept of an electronic stethoscope equipped with an automatic heart tone identification system appears to be the best solution. Thanks to the advancement in technology, the quality of phonocardiography signals is no longer an issue. However,...
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Paenibacillus alvei MP1 as a Producer of the Proteinaceous Compound with Activity against Important Human Pathogens, Including Staphylococcus aureus and Listeria monocytogenes
PublicationAn emerging need for new classes of antibiotics is, on the one hand, evident as antimicrobial resistance continues to rise. On the other hand, the awareness of the pros and cons of chemically synthesized compounds’ extensive use leads to a search for new metabolites in already known reservoirs. Previous research showed that Paenibacillus strain (P. alvei MP1) recovered from a buckwheat honey sample presented a wide spectrum of...