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Search results for: human-computer%20interaction
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Oxidative modification induced by photodynamic therapy with Photofrin®II and 2-methoxyestradiol in human ovarian clear carcinoma (OvBH-1) and human breast adenocarcinoma (MCF-7) cells
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Flow cytometric sorting and analysis of human epidermal stem cell candidates
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Seidel–Herzel model of human baroreflex in cardiorespiratory system with stochastic delays
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Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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Molecular action of isoflavone genistein in the human epithelial cell line HaCaT
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Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin
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Temozolomide and sorafenib as programmed cell death inducers of human glioma cells
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Protective effect of desloratadine against oxidative stress in human erythrocytes in vitro
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High Concentrations of Excised Oxidative DNA Lesions in Human Cerebrospinal Fluid
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Can the SARS-CoV-2 virus damage human hearing and balance?
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Identification of two novel mutations in human acute myeloid leukemia cases
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Impact of Infant and Maternal Factors on Energy and Macronutrient Composition of Human Milk
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The role of the enzymatic antioxidant system in cylindrospermopsin-induced toxicity in human lymphocytes
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Toxicity of cylindrospermopsin in human lymphocytes: Proliferation, viability and cell cycle studies
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Modeling human thinking about similarities by neuromatrices in the perspective of fuzzy logic
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Investigating Preattentive Features for Modelling Human Behaviour During Visual Search
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Preventing Work-Related Musculoskeletal Disorders in Manufacturing by Digital Human Modeling
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Procedure of determination of volatile trihalomethanes in human urine with pervaporation and gas chromatography
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Metal status in human endometrium: Relation to cigarette smoking and histological lesions
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Non-Newtonian lubrication of human hip joint for unsteady impulsive motion
PublicationTematem niniejszej pracy są parametry smarowania lepkosprężystą cieczą synowialną stawu biodrowego człowieka w czasie kilku, kilkunastu a nawet kilkudziesięciu mikrosekund po doznanym urazie. W niniejszej pracy rozpatruje się urazy wywołujące zmniejszenie lub zwiększenie wysokości i zmiany kształtu szczeliny stawu, które to zmiany po pewnym określonym czasie po doznanym urazie mogą zanikać. W konsekwencji takich urazów i to w...
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Procedure of determination of volatile trihalomethanes in human urine with perwaporation and gas chromatography
PublicationPraca przedstawia wyznaczanie podstawowych parametrów walidacyjnych nowej procedury oznaczania lotnych związków chlorowcoorganicznych z grupy trihalometanów w próbkach moczu ludzkiego, opartej na zastosowaniu:- techniki perwaporacji na etapie izolacji i wzbogacania analitów;- bezpośredniego dozowania próbek ekstraktów (permeatu) do kolumny chromatograficznej;- chromatograficznego rozdzielanie mieszaniny na poszczególne składniki;-wykorzystaniu...
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Human proteinase 3 resistance to inhibition extends to alpha‐2 macroglobulin
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Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity
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Substrate specificity and inhibitory study of human airway trypsin-like protease
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Molecular features of thymidine analogues governing the activity of human thymidine kinase
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Lead in human teeth dentine as a bio-indicator of environmental exposure to lead
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Numerical contribution to the viscoelastic magnetic lubrication of human joint in periodic motion.
PublicationPraca przedstawia rozwiązania problemu smarowania stawów człowieka w układzie współrzędnych ortogonalnych krzywoliniowych dla ruchu nieustalonego okresowego w polu magnetycznym. Uwzględnia się lepkosprężyste właściwości cieczy synowialnej w trakcie smarowania
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Studies of the effects of antifungal cationic derivatives of amphotericin B on human erythrocytes.
PublicationBadano nową grupę kationowych pochodnych amfoterycyny B pod kątem zależności pomiędzy ich zdolnością do asocjacji i selektywną toksycznością. We wszystkich przypadkach stosowano amfoterycynę B jako związek odniesienia. Jako miarę efektu toksycznego in vitro badanych związków stosowano wypływ wewnątrzkomórkowego potasu oraz hemolizę. Miarą aktywności przeciwgrzybowej był MIC i utrata potasu wewnatrzkomórkowego. Do oceny stopnia...
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Methodology for incorporating the human and organizational factors inqualitative and quantative risk assessments
PublicationZaproponowano metodykę systematycznego uwzględniania czynników ludzkich i organizacyjnych w jakościowych i ilościowych modelach ryzyka stosując hierarchiczne diagramy wpływu (HID). Współczynniki wagowe i skalowe czynników wpływu w HID określone są odpowiednio na podstawie wiedzy ogólnej i audytu danego systemu. Metodykę zaimplementowano w programie komputerowym zaprojektowanym do obliczeń złożonych HID
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Risk analysis and functional safety assessment with regard to human andorganisational factors
PublicationReferat poświęcono wybranym zagadnieniom analizy ryzyka i zarządzania bezpieczeństwem funkcjonalnym systemów związanych z bezpieczeństwem. Systemy takie, zawierające coraz częściej jednostki programowalne, są potencjalnie narażone na błędy człowieka, które mają swoje źródło w uchybieniach organizacyjnych. W procesie analizy ryzyka takich systemów proponuje się stosować metody jakościowe i ilościowe. Potencjalne błędy człowieka...
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An electrochemical interface for direct analysis of amlodipine in tablets and human blood samples
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Increased expression of PELP1 in human sperm is correlated with decreased semen quality
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Expression of ghrelin and ghrelin functional receptor GHSR1a in human pituitary adenomas
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Interaction of selected divalent metal ions with human ataxin-3 Q36
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The Influence of The Light-Activated Titania P25 on Human Breast Cancer Cells
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IMPLANT USED IN HERNIA REPAIR UNDER PHYSIOLOGICAL MOVEMENTS OF HUMAN ABDOMEN
PublicationThe study deals with the mechanical behaviour of implant used in repair of abdominal hernia. The influence of orientation of the orthotropic implants in different areas of abdominal wall is studied.
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A novel chemiluminescent immunoassay for detection of Toxoplasma gondii IgG in human sera
PublicationThis study describes Toxoplasma gondii IgG chemiluminescent immunoassay (CLIA) based on the use of a novel immunochemical reagents in the form of the conjugates of original acridinium ester (AE) labels attached to antibodies and SAG2-GRA1-ROP1L chimeric antigen and shows that this test is useful for diagnostic purposes.
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Numerical Model of the Aortic Valve Implanted Within Real Human Aorta
PublicationCardiovascular system diseases are the main cause of deaths in developed and developing countries. The main reasons are myocardial infarction, heart failure, stroke and valvular diseases. These are caused mainly by arteriosclerosis. The valvular diseases involve a significant burden for the health care system and their frequency is rising with the patient age. This work describes the tools and numerical models appropriate for modeling...
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Measurements of surface roughness of heads of human hip joints in lubrication aspects
PublicationW niniejszej pracy przedstawiono wyniki pomiarów chropowatości chrząstki stawowej na powierzchniach głów kostnych stawu biodrowego człowieka. Pomiarów dokonano przy pomocy czujników mechanicznych i laserowych. Praca zawiera wyniki analizy statystycznej.
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Investigations to realize thermal, humid and human comfort in modern living houses.
PublicationPrzedstawiono badania nad komfortem cieplnym, wilgotnościowym i psychicznym w domkach mieszkalnych. Wykonano pomiary oraz przeprowadzono ankiety. Zastosowano różne sposoby wentylacji.
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Computer Aided Manufacturing Systems (M:320417W0) Mechatronika sem. 1, 2022/2023 lato
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A novel chemiluminescent immunoassay based on original acridinium ester labels as better solution for diagnosis of human toxoplasmosis than conventional ELISA test
PublicationToxoplasma gondii infection is one of the most common human zoonosis. Laboratory diagnosis of this disease is mainly based on the results of serological methods detecting specific antibodies in the patient’s sera. In this study we aimed to evaluate the performance of a chemiluminescence immunoassay (CLIA) based on the use of a novel immunochemical reagent in the form of the conjugate of original acridinium label (AL) attached to...
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Brain-computer interaction based on EEG signal and gaze-tracking information = Analiza interackji mózg-komputer wykorzystująca sygnał EEg i informacje z systemu śledzenia punktu fiksacji wzroku
PublicationThe article presents an attempt to integrate EEG signal analysis with information about human visual activities, i.e. gaze fixation point. The results from gaze-tracking-based measurement were combined with the standard EEG analysis. A search for correlation between the brain activity and the region of the screen observed by the user was performed. The preliminary stage of the study consists in electrooculography (EOG) signal processing....
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Three-dimensional modeling and automatic analysis of the human nasal cavity and paranasal sinuses using the computational fluid dynamics method
PublicationPurpose The goal of this study was to develop a complete workflow allowing for conducting computational fluid dynam- ics (CFD) simulation of airflow through the upper airways based on computed tomography (CT) and cone-beam computed tomography (CBCT) studies of individual adult patients. Methods This study is based on CT images of 16 patients. Image processing and model generation of the human nasal cavity and paranasal sinuses...
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Occurrence and levels of polybrominated diphenyl ethers (PBDEs) in house dust and hair samples from Northern Poland; an assessment of human exposure
PublicationPolybrominated diphenyl ethers (PBDEs) are among most ubiquitous compounds to be found in indoor environment and ingestion of household dust is considered an important route of exposure to PBDEs, especially in toddlers and young children. The present work reported concentration levels of PBDE congeners (PBDE-28, -47, -99, -100, -153, -154, -183 and -209) in hair and dust samples from selected households from Northern Poland. The...
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A new human IgG avidity test, using mixtures of recombinant antigens (rROP1, rSAG2, rGRA6), for the diagnosis of difficult-to-identify phases of toxoplasmosis
PublicationThe preliminary diagnostic utility of two mixtures of Toxoplasma gondii recombinant antigens (rROP1+rSAG2 and rROP1+rGRA6) in IgG ELISA and IgG avidity test has been evaluated. A total of 173 serum samples from patients with toxoplasmosis and seronegative people were examined. The sensitivity of IgG ELISA for rROP1+rSAG2 and rROP1+rGRA6 was 91.1% and 76.7%, respectively, while the reactivity for sera from patients where acute toxoplasmosis...
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Humanistic Scientific Fascicles Human Rights
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No Evidence for Sex-specificity in Vitamin C, E and Fatty Acid Content of Human Milk from Healthy Polish Mothers
PublicationHuman milk (HM) is a complex fluid that meets the nutritional needs of infants. Its composition idrfs associated with environmental, maternal, and foetal variables. It provides nutrients and bioactive substances, including cytokines, immunoglobulins, and constituents with antioxidative properties. Boys are reportedly more susceptible to oxidative stress. This study aimed to determine the relationship between infant sex and the...
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Imidazoacridinone antitumor agent C-1311 as a selective mechanism- based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes.
Publication5-Diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311), a promising antitumor agent that is also active against autoimmune diseases, was determined to be a selective inhibitor of the cytochrome P450 (CYP) 1A2 and 3A4 isoenzymes. Therefore, C-1311 might modulate the effectiveness of other drugs used in multidrug therapy. The present work aimed to identify the mechanism of the observed C-1311-mediated inactivation of CYP1A2...
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Rapid Characterization of the Human Breast Milk Lipidome Using a Solid-Phase Microextraction and Liquid Chromatography-Mass Spectrometry-Based Approach.
PublicationHuman breast milk (HBM) is a biofluid consisting of various biomolecules such as proteins, lipids, carbohydrates, minerals and bioactive substances. Due to its unique and complex composition, HBM provides not only nutritional components required for the growth of the infant, but also additional protection against infections. Global insight into the composition of HBM is crucial to understanding the health benefits infants receive...
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Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling
PublicationTree saps are nourishing biological media commonly used for beverage and syrup production. Although the nutritional aspect of tree saps is widely acknowledged, the exact relationship between the sap composition, origin, and effect on the metabolic rate of human cells is still elusive. Thus, we collected saps from seven different tree species and conducted composition-activity analysis. Saps from trees of Betulaceae, but not from...
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Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
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Rough Set Based Modeling and Visualization of the Acoustic Field Around the Human Head
PublicationThe presented research aims at modeling acoustical wave propagation phenomena by applying rough set theory in a novel manner. In a typical listening environment sound intensity is determined by numerous factors: a distance from a sound source, signal levels and frequencies, obstacles’ locations and sizes. Contrarily, a free-field is characterized by direct, unimpeded propagation of the acoustical waves. The proposed approach is...
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Erratum to: Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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A Comparison of ABTS and DPPH methods for assessing the total antioxidant capacity of human milk
PublicationCałkowitą zdolność przeciwutleniająca (TAC) mleka ludzkiego odzwierciedla zawartość i aktywność w mleku składników, które zapobiegają degradacji tłuszczów i białek na drodze utlenienia. Celem badania było porównuje testu ABTS i DPPH w odniesieniu do odzysku, precyzji i czułości (granica wykrywalności i oznaczalności) obu metod służących do oznaczania wartości TAC mleka ludzkiego. Wartości TAC zostały określone dla dwudziestu pięciu...
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Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes
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Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone
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Investigating Human Visual Behavior by Hidden Markov Models in the Design of Marketing Information
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The effect of electromagnetic field on reactive oxygen species production in human neutrophilsin vitro
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Human Granulosa Cells—Stemness Properties, Molecular Cross-Talk and Follicular Angiogenesis
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The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C
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Theoretical Study on Interactions of Bicyclic Vasopressin Analogues with Human Neurohypophyseal Hormone Receptors
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Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1
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A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome
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Inhibition of Human and Yeast 20S Proteasome by Analogues of Trypsin Inhibitor SFTI-1
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A new proteinase 3 substrate with improved selectivity over human neutrophil elastase
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Studies of human and veterinary drugs' fate in environmental solid samples- analytical problems.
PublicationW różnych ośrodkach naukowych na całym świecie trwają prace nad poznaniem losu środowiskowego zanieczyszczeń z grupy farmaceutyków. Obecność pozostałości farmaceutycznych w poszczególnych elementach środowiska stanowi nowe wyzwanie zarówno z punktu widzenia technologii oczyszczania wód i ścieków jak i analityków, których zadaniem jest opracowanie nowych metodyk analitycznych. W publikacji przedstawiono problemy z jakimi stykają...
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The formal safety assessment and influence of human factor in application to chosen ship's type
PublicationTragedia jednego ze statków typu ro-ro pokazała podatność tego typu statków na utratę stateczności, przewrócenie się, a w ostateczności zatonięcie. Wszystkie ro-rowce charakteryzują się małym zanurzeniem, a wynurzona część kadłuba podatna jest na działanie wiatru. Jeżeli dodatkowo w takich warunkach dochodzi element nieprawidłowego rozmieszczenia pojazdów i ich słabego zamocowania to groźba przesunięcia ładunku staje się realna....
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The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
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A Redundant Role of Human Thyroid Peroxidase Propeptide for Cellular, Enzymatic, and Immunological Activity
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The propeptide of human thyroid peroxidase is not required for its cellular, enzymatic or immunological activity
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THE IMPACT OF EMOTIONS ON CHANGES IN THE CORRELATION COEFFICIENT BETWEEN DIGITAL IMAGES OF THE HUMAN FACE
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Voriconazole-Based Salts Are Active against Multidrug-Resistant Human Pathogenic Yeasts
PublicationVoriconazole (VOR) hydrochloride is unequivocally converted into VOR lactates and valinates upon reaction with silver salts of organic acids. This study found that the anticandidal in vitro activity of these compounds was comparable or slightly better than that of VOR. The Candida albicans clinical isolate overexpressing CaCDR1/CaCDR2 genes, highly resistant to VOR, was apparently more susceptible to VOR salts. On the other hand,...
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Apoptosis of human leukemia cells induced by imidazoacridinone derivative C-1311 (Symadex)
PublicationPraca dotyczy różnej wrażliwości komórek białaczek ludzkich do ulegania apoptozie pod wpływem pochodnej imidazoakrydonu C-1311, co jest zgodne z aktywnością cytotoksyczną tego związku (EC90) wobec badanych komórek.
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Comparisson between impulsive and periodic non-newtonian lubrication of human hip joint
PublicationOpis smarowania powierzchni sferycznych stawu biodrowego człowieka przedstawiono w aspektach hydromechaniki, przy pomocy równań zachowania pędu i ciągłości strugi dla osiowo niesymetrycznego przepływu cieczy lepkosprężystej z wykorzystaniem związków konstytutywnych Rivlina Ericksena we współrzędnych sferycznych.
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublicationImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Combined anticancer therapy with imidazoacridinone analogue C‐1305 and paclitaxel in human lung and colon cancer xenografts—Modulation of tumour angiogenesis
PublicationThe acridanone derivative 5-dimethylaminopropylamino- 8- hydroxytriazoloacridinone (C-1305) has been described as a potent inhibitor of cancer cell growth. Its mechanism of action in in vitro conditions was attributed, among others, to its ability to bind and stabilize the microtubule network and subsequently exhibit its tumour- suppressive effects in synergy with paclitaxel (PTX). Therefore, the objective of the present study...
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Sound Field Intensity Measurements and Visualization around the Human Head Model . Rozkłąd natężenia pola akustycznego w komorze bezechowej obecności sztucznej głowy i w przypadku braku jej obecności
PublicationThe main goal of this research study was to measure and visualize sound field intensity distribution in and without presence of the human head model. Measurements were performed in the anechoic chamber with the 5 cm grid. Experimental setup consisted of a multitone generator, two loudspeakers, human head model, intensimetric probe, the Cartesian robot applied for precise positioning of the acoustic sensor, and an analyzer. Based...
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Trees as a Shading System for Streets on the East–West Axis: Computer Simulations for the Selected Geometrical Proportions of Building Developments in Humid Continental Climate
PublicationThe study is aimed at investigating the possibilities for solar protection provided to the street canyon located on the E–W axis and with the following profiles: shallow (height/width (H/W) = 0.2, 0.6, and 1) and deep (H/W = 2) by two rows of trees located at a distance of 3 m away from southern and northern façades. The research was based on numerical simulation analyses conducted in the Rhinoceros® program, with the application...
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When Biobanks Meet Religion: Association Between Religiosity and Attitudes of Polish Medical Students Toward Biobanking of Human Biological Material for Research Purposes
PublicationWhile biobanking is expanding globally, the empirical evidence concerning the impact of religion on future healthcare professionals’ awareness and willingness to donate biospecimens for biobank research is lacking. To understand how medicalstudents’ religious beliefs can fuel their questions regarding how biospecimens would be stored, cared for, and used, we conducted a survey among 1500 medical students at Poznań University...
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublicationPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Fluorescence studies by quenching and protein unfolding on the interaction of bioactive compounds in water extracts of kiwi fruit cultivars with human serum albumin
PublicationThe main aim of this investigation was to characterize new kiwi fruit cultivars after cold storage treatment and to determine the similarities and differences between them, using spectroscopic methods. The chemometric comparison of kiwi fruit cultivars based on physicochemical indices during cold storage was carried out. All kiwi fruit cultivars showed a high level of correlation between the contents of phenolic compounds (polyphenols,...
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Human poverty - measuring relative deprivation from basic achievements: a comparative study for 144 countries over the period 1990-2010
PublicationPoverty – differently defined and measured – still remains one the crucial parts of the world development debate. It`s broadly perceived as multidimensional phenomenon which deprives people from basic capabilities and freedoms, limits their opportunity to educate and fully participate in the labor market contributing to overall country`s socioeconomic performance. Referring to seminal works of Sen and many others(see e.g. Morris...
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Modification of gradient HPLC method for determination of small molecules' affinity to human serum albumin under column safety conditions: Robustness and chemometrics study
PublicationIn the early stages of drug discovery, beyond the biological activity screening, determining the physicochemical properties that affect the distribution of molecules in the human body is an essential step. Plasma protein binding (PPB) is one of the most important investigated endpoints. Nevertheless, the methodology for measuring %PPB is significantly less popular and standardized than other physicochemical properties, like lipophilicity....
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Determination of cytotoxic activity of new bisacridines IKE18, IKE19, IKE21 and IE10 against human kidney HEK-293 (ATCC® CRL-1573™) and liver cells HEPG2 (ATCC® HB-8065™)
Open Research DataThe datasets contain the results of determining in vitro cytotoxic activity of compounds using human cell lines assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, a method that evaluates cell viability by measuring cellular oxidoreductase activity. Initially, cells were seeded in 96-well culture plates and allowed...
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Asia Pacific Journal of Human Resources
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BMC International Health and Human Rights
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Human Gene Therapy Clinical Development
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Environmental Hazards-Human and Policy Dimensions
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IEEE Transactions on Human-Machine Systems
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Journal of Human Behavior in the Social Environment
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Journal of Gynecology Obstetrics and Human Reproduction
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South African Journal on Human Rights
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Journal of Chinese Human Resources Management
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Human-centric Computing and Information Sciences
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International Journal of Technology and Human Interaction
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Human Resource Management International Digest
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HOMO-JOURNAL OF COMPARATIVE HUMAN BIOLOGY
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Sur - International Journal of Human Rights
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Journal of Human Rights and Social Work
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