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Application of the near-infrared spectroscopy in the pharmaceutical technology
PublicationNear-infrared (NIR) spectroscopy is currently the fastest-growing and the most versatile analytical method not only in the pharmaceutical sciences but also in the industry. This review focuses on recent NIR applications in the pharmaceutical technology. This article covers monitoring, by NIR, of many manufacturing processes, such as granulation, mixing or drying, in order to determine the end-point of these processes. In this...
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Detection of some volatile degradation products released during photoexposition of ranitidine in a solid state
PublicationRanitidine (RAN) is on top of the list of prescribed drugs, due to its popularity as a selective H2-receptor antagonist, which efficiently decreases the amount of acid produced in the stomach. RAN is not stable both in a solid state and in a solution, which creates manufacturing problems, requires appropriate storage conditions, and results in a short drug shelf-life. The aim of this work was to study the emission of volatile...
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Determination of API content in a pilot-scale blending by near-infrared spectroscopy as a first step method to process line implementation
PublicationNear infrared (NIR) spectroscopy was used for estimation of powder blend homogeneity and manufacturing control of a medicinal product powder mixture containing active pharmaceutical ingredient (API). Aiming at initiating a Process Analytical Technology (PAT) activity, the first step was a stationary mode atline evaluation. In this, the content of pharmaceutical active compound in the powder mixtures intended to the direct tabletting...
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Two-step Conversion of Crude Glycerol Generated by Biodiesel Production into Biopolyols: Synthesis, Structural and Physical Chemical Characterization
PublicationIn this work biopolyols were synthesized via two-step process from crude glycerol and castor oil. For better evaluation of analyzed process, the impact of its time and temperature on the structure and properties of biopolyols was determined. Obtained results fully justified conducting of synthesis in two steps. Prepared materials were characterized by hydroxyl value and water content comparable to polyols industrially applied in...
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Towards Experience-Based Smart Product Design for Industry 4.0
PublicationThis paper presents the concept of smart virtual product development (SVPD) system capable of supporting industrial product development process. It enhances the decision making process during different stages and activities involved in product development i.e. product design, manufacturing, and its inspection planning. The enhancement is achieved by using the explicit knowledge of formal past decision events, which are captured,...
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EXPERIMENTAL EVALUATION OF DLC/STEEL SLIDING CONTACTS’ OPERATIONAL ENVELOPE
PublicationIn an industrial project concerning sliding bearings, a sliding pair was selected of high alloy steel vs. industrial grade DLC coated high alloy steel as a basis for an innovative design of high performance sliding bearings lubricated with a synthetic oil for use in geared transmission units. The development process required credible data on the ultimate resistance of the sliding pair to very high contact stress. An experimental...
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Evaluation of adhesive forces and the specific surface energy of zirconia stabilized by yttria with alumina additions ceramic by AFM method
PublicationThe adhesive forces and the specific surface energy of ceramic material surfaces are very important for further tribological and biomedical applications of ceramics. Partially stabilized zirconia (zirconium oxide) is popular for manufacturing various medical products. ZrO2 stabilized by Y2O3 with additions of 5 wt% alumina was produced by slip casting method with a subsequent sintering. Structure and chemical composition of ceramic...
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RAMAN DIAGNOSTICS OF CVD DIAMOND GROWTH
PublicationDevelopment of Raman spectroscopic system for diagnostics of growth of diamond and BDD (Boron- Doped-Diamond) thin films during μPA CVD (Microwave Plasma Assisted Chemical Vapour Deposition) process is described. Raman studies of such films were carried out as in-situ monitoring of film deposition as ex-situ measurements conducted for a sample outside the reaction vessel after manufacturing process. Modular system for the in-situ...
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Defence in depth conception in nuclear power plants and requirements for instrumentation and control systems
PublicationThe aim of this article is to identify and discuss some issues of the safety systems’ design for nuclear power plants equipped with the light water reactors using a defence in depth (D-in-D) conception. Because the functional safety solutions play nowadays an important role for the risk control, the basic requirements for the instrumentation and control systems are specified with regard to relevant international standards. For...
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Biomimetic torene shells
PublicationThe genome inside the eukaryotic cells is guarded by a unique shell structure, called the nuclear envelope (NE), made of lipid membranes. This structure has an ultra torus topology with thousands of torus-shaped holes that imparts the structure a high flexural stiffness. Inspired from this biological design, here we present a novel ‘‘torene’’ architecture to design lightweight shell structures with ultra-stiffness for engineering...
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Development of novel smartphone-based methods of wine quality assessment
PublicationThe doctoral dissertation concerns the development of novel smartphone-based analytical methods of wine quality evaluation, which would be in line with the stipulations of green and equitable analytical chemistry. This solution is based on the analysis of biogenic amines and selected bioactive compounds. The dissertation is based on four articles containing the results of research which led to the development of smartphone-based...
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Influence of Water-Induced Degradation of Polytetrafluoroethylene (PTFE)-Coated Woven Fabrics Mechanical Properties
PublicationThe impact of water-induced degradation on the mechanical properties of the chosen two PTFE-coated, glass threads woven fabrics is investigated in this paper. The paper begins with a survey of literature concerning the investigation and determination of coated woven fabric properties. The authors carried out the uniaxial tensile tests with an application of flat and curved grips to establish the proper values of the ultimate tensile...
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Integrated Functional Safety and Cybersecurity Evaluation in a Framework for Business Continuity Management
PublicationThis article outlines an integrated functional safety and cybersecurity evaluation approach within a framework for business continuity management (BCM) in energy companies, including those using Industry 4.0 business and technical solutions. In such companies, information and communication technology (ICT), and industrial automation and control system (IACS) play important roles. Using advanced technologies in modern manufacturing...
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Three-Dimensional Printing of Bone Models
PublicationThe trabecular bone occurs, for example, in the femoral heads. Understanding the phenomenon of bone tissue degeneration can be the basis for the possibility of looking for alternative methods of surgical treatment of bone loss. The paper presents the results of the trabecular bone model, which was produced in additive manufacturing method with fused filament fabrication technology. The verification of the mechanical behavior of...
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Comparative Study of the Reinforcement Type Effect on the Thermomechanical Properties and Burning of Epoxy-Based Composites
PublicationAramid (AF), glass (GF), carbon (CF), basalt (BF), and flax (FF) fibers in the form of fabrics were used to produce the composites by hand-lay up method. The use of fabrics of similar grammage for composites’ manufacturing allowed for a comprehensive comparison of the properties of the final products. The most important task was to prepare a complex setup of mechanical and thermomechanical properties, supplemented by fire behavior...
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A CONCEPT DESIGN OF DIESEL – HYDRAULIC PROPULSION SYSTEM FOR PASSENGER SHIP INTENDED FOR INLAND SHALLOW WATER NAVIGATION
PublicationThis paper presents an analysis of environmental and technical conditions necessary for working out a possibly most favourable propulsion system for a two – segment passenger ship intended for navigation between Berlin and Kaliningrad. There are presented various types of propulsion systems for small ships as well as analyzed their possible applications and consequences. In this work there were taken into account system’s reliability,...
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BeesyBees: A mobile agent-based middleware for a reliable and secure execution of service-based workflow applications in BeesyCluster
PublicationIntegrating distributed services into workflows comes with its own set of challenges, including security, coordination, fault tolerance and optimisation of execution time. This paper presents an architecture and implementation - nicknamed BeesyBees - that allows distributed execution of workflow applications in BeesyCluster using agents. BeesyCluster is a middleware that allows users to access distributed resources as well as publish...
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Oxygen vacancy-enriched V2O5·nH2O nanofibers ink for universal substrates-tolerant and multi means-integratable NH3 sensing
PublicationUniversal substrates-tolerant and multi means-integratable ammonia (NH3) sensing is highly desired in future Internet of Things in environmental monitoring, food security and early diagnosis of human diseases, however, is still less than satisfactory. Here, an oxygen vacancy-governed NH3 sensing has been developed with V2O5·nH2O nanofibers (NFs) ink, via combined thermal decomposition of ammonium metavanadate and dilution. As-obtained...
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Synthetic lipopeptides as potential topical therapeutics in wound and skin care: in vitro studies of permeation and skin cells behaviour
PublicationSeveral Gly-His-Lys analogues were obtained to investigate their antimicrobial properties. Three lipophilic analogues with the structure numbering 1b, 2b, 4b, exhibit significant effect against bacteria and were selected for in vitro evaluation of skin cells behaviour. In the present studies, an in vitro model of wound repair, proliferative cell staining, and tracking of living cells were used. Cell proliferation and cell migration,...
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Nietechnologiczne nie znaczy gorsze. Rzecz o innowacjach
PublicationInnowacje nietechnologiczne nie zajmują istotnego miejsca w dyskursie naukowym jak i praktycznym. Zauważona luka badawcza oraz brak praktycznych rozwiązań wspierających innowacje nietechnologicznie, były motywem podjęcia tego tematu przez międzynarodowy zespół, składający się z badaczy z czterech krajów (Danii, Finlandii, Litwy i Polski) oraz szeregu instytucji wspierających biznes, w tych krajach, pełniących funkcje pośredników...
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Ciliated protozoa in the impact zone of the Uzhgorod treatment plant
PublicationThis paper presents the results of studies on the Uzh River (Ukraine, Zakarpattia Oblast) near the effluent point of a sewage treatment plant in Uzhgorod. The samples were taken at various sites of the treatment plant along the stages of purification process, as well as in the river, at a number of different points above and below the wastewater discharge. At each of these objects, the temperature...
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In Silico Safety Assessment of Bacillus Isolated from Polish Bee Pollen and Bee Bread as Novel Probiotic Candidates
PublicationBacillus species isolated from Polish bee pollen (BP) and bee bread (BB) were characterized for in silico probiotic and safety attributes. A probiogenomics approach was used, and in-depth genomic analysis was performed using a wide array of bioinformatics tools to investigate the presence of virulence and antibiotic resistance properties, mobile genetic elements, and secondary metabolites. Functional annotation and Carbohydrate-Active...
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Editorial for the special issue on advances in forward and inverse surrogate modeling for high-frequency design
PublicationThe design of modern‐day high‐frequency devices and circuits, including microwave/RF, antenna and photonic components, historically has relied on full‐wave electromagnetic (EM) simulation tools. Initially used for design verification, EM simulations are nowadays used in the design process itself, for example, for finding optimum values of geometry and/or material parameters of the structures of interest. In a growing number of...
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Skilled-Unskilled Wage Gap Versus Evolving Trade And Labour Market Structures in the EU
PublicationThis paper proposes an alternative approach to the empirical study of wage gap between workers with different educational levels in the enlarged EU. The analysis is based on sectoral database, linking labor market statistics and trade data at the level of 12 manufacturing sectors in a group of 20 European countries: selected New Member States (NMS-5) and former EU-15 economies, in the period 1995-2005. The results of the empirical...
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The EU enlargement and domestic employment
PublicationThe study focuses on the interactions between EU member states' labor markets (manufacturing and tradable business services) over the period 1995-2005. We use recently released detailed sector level employment statistics, considering the effects of trade integration on the creation of links between labor force in ''Old'' and ''New'' partners in the enlarged EU. Empirical estimations show that the domestic demand for labor in the...
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An analysis of the characteristics of Indonesian industrial sectors: 2005-2010
PublicationThe purpose of the current study is to analyze the characteristics of Indonesian industrial sectors from 2005 through 2010. The study employs the analysis instruments from the Input-Output (IO) analysis, namely the indices of the power of dispersion, and the sensitivity of dispersion. For 2005 and 2010, the study focuses on nine and seventeen industries, respectively. The results show that industry 3, manufacturing, placed the...
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The ranks of Indonesian and Japanese industrial sectors: A further study
PublicationThe purpose of the current study is to extend the previous study which analyzes the industrial sectors ranks of specific countries. More specifically, the study aims to conduct a further analysis regarding the ranks by using the new data as well as new analysis periods. The study focuses on the cases of Indonesia and Japan. In this study, the analysis period of the Indonesian case is 2010 while for the case of Japan is 2011. Using...
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Enhancing Product Innovation Through Smart Innovation Engineering System
PublicationThis paper illustrates the idea of Smart Innovation Engineering (SIE) System that helps in carrying the process of product innovation. The SIE system collects the experiential knowledge from the formal decisional events. This experiential knowledge is collected from the set of similar products having some common functions and features. Due to the fact that SIE system collects, captures and reuses the experiential knowledge of all...
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The ranks of Indonesian and Japanese industrial sectors: A further study
PublicationThe purpose of the current study is to extend the previous study which analyzes the industrial sectors ranks of specific countries. More specifically, the study aims to conduct a further analysis regarding the ranks by using the new data as well as new analysis periods. The study focuses on the cases of Indonesia and Japan. In this study, the analysis period of the Indonesian case is 2010 while for the case of Japan is 2011. Using...
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COMPARATIVE ANALYSES OF INTERNATIONALIZATION OF KAZAKHSTAN ENTERPRISES
PublicationThis paper presents the instruments of internationalization of enterprises operating within the Eurasian Economic Union. Research contains answers of 108 enterprises exporters located in the Republic of Kazakhstan. The purpose of the paper is to show the main forms of the internationalization of enterprises in Kazakhstan. The paper also presents the following instruments of enterprises’ internationalization including: indirect...
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An analysis of the characteristics of Indonesian industrial sectors: 2005-2010
PublicationThe purpose of the current study is to analyze the characteristics of Indonesian industrial sectors from 2005 through 2010. The study employs the analysis instruments from the Input-Output (IO) analysis, namely the indices of the power of dispersion, and the sensitivity of dispersion. For 2005 and 2010, the study focuses on nine and seventeen industries, respectively. The results show that industry 3, manufacturing, placed the...
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Virtual Engineering Objects (VEO): Designing, Developing and Testing Models
PublicationIn this article, the development and implementation of the concept of Virtual Engineering Object (VEO) is described. A VEO is a computerized real world representation of an engineering object. VEO will act as a living representation of the object capable of adding, storing, improving and sharing knowledge through experience, in a way similar to an expert of that object. In this paper, it is shown through test models how the concept...
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PROJECT OF AN TDC SIGNAL DISTRIBUTOR PROTOTYPE WITH GAL-VANIC SEPARATION DESTINED FOR STUDIES OF THE BEGINNING OF SELFIGNITION USING LANGMUIR PROBE
PublicationThe knowledge of pistons' TDC is crucial while performing any kind of measurement beneficial to diagnostic inference of a diesel engine. The research of engines under exploitation often cause impartial difficulties with, eg. capability of probe installation. Therefore, it becomes crucial to minimalize those. The paper presents a description of a TDC impulse distributor - divider that provides signal delivery to more than one measurement...
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Comparative tests of the wall thickness effect of a glass-reinforced thermosetting plastic coating with a non-circular cross section in a soil-coating object for economic aspect
PublicationCulvert structures made of plastics are employed extensively in the construction of new facilities as well as the renovation of existing ones. Due to the high costs of materials required for the manufacturing of these goods, the objective of this research is focused to lessen the thickness of the walls, which may, on the other hand, result in a reduction in the stiffness of the system. In the course of the testing, the structure...
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Protein overproduction alters exosome secretion in Chinese hamster ovary cells
PublicationDespite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chi-nese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular vesicles (EVs) by protein overexpressing CHO cells was demonstrated with protein content assay, nanoparticle tracking analysis, and...
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Quantifying wage effects of offshoring: import- versus export-based measures of production fragmentation
PublicationIn this paper we examine the implications of international fragmentation of production on wages in the light of recent methodological developments in offshoring measurement. In particular, we compare the results stemming from two ways of quantifying offshoring – the traditional one based on import statistics and the one obtained from the decomposition of gross exports and input-output information. In the empirical part of our study,...
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Fast Design Optimization of Waveguide Filters Applying Shape Deformation Techniques
PublicationThis paper presents an efficient design of microwave filters by means of geometry optimization using shape deformation techniques. This design procedure allows for modelling complex 3D geometries which can be fabricated by additive manufacturing (AM). Shape deforming operations are based on radial basis function (RBF) interpolation and are integrated into an electromagnetic field simulator based on the 3D finiteelement method (FEM)....
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Recent advances in aqueous virus removal technologies
PublicationThe COVID-19 outbreak has triggered a massive research, but still urgent detection and treatment of this virus seems a public concern. The spread of viruses in aqueous environments underlined efficient virus treatment processes as a hot challenge. This review critically and comprehensively enables identifying and classifying advanced biochemical, membrane-based and disinfection processes for effective treatment of virus-contaminated...
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Polyurethanes
PublicationHandbook of Thermoset Plastics, Fourth Edition provides complete coverage of the chemical processes, manufacturing techniques and design properties of each polymer, along with its applications. This new edition has been expanded to include the latest developments in the field, with new chapters on radiation curing, biological adhesives, vitrimers, and 3D printing. This detailed handbook considers the practical implications of using...
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REVIEW OF CURRENT RESEARCH ON CHITOSAN AS A RAW MATERIAL IN THREE-DIMENSIONAL PRINTING TECHNOLOGY IN BIOMEDICAL APPLICATIONS
PublicationThree-dimensional (3D) biomaterial manufacturing strategies show an extraordinary driving force for the development of innovative solutions in the biomedical sector, including drug delivery systems, disease modelling and tissue and organ engineering. Due to its remarkable and promising biological and structural properties, chitosan has been widely studied for decades in several potential applications in the biomedical field. However,...
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Is Germany a Hub of ‘Factory Europe’ for CEE Countries?
PublicationThe goal of the paper is to decompose gross exports and imports to/from Germany for seven selected economies in Central and Eastern Europe (CEE): the Czech Republic, Estonia, Hungary, Lithuania, Latvia, Poland and Slovakia for 2000 and 2014, in order to identify the role of Germany in absorbing, reflecting and redirecting CEE trade. The authors use a gross trade decomposition proposed by Bonin and Mancini (2017), which is the extended...
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The Smith-Watson-Topper parameter and fracture surface topography relationship for additively manufactured 18Ni300 steel subjected to uniaxial variable-amplitude loading
PublicationIn this paper, the association between Smith-Watson-Topper (SWT) parameter and fracture surface topography is studied in additively manufactured maraging steel exposed to variable-amplitude fatigue loading. The post-failure fracture surfaces were examined using a non-contact 3D surface topography measuring system and the entire fracture surface method. The focal point is on the correspondence between fatigue characteristics, articulate...
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Algorytm kontroli jakości z elementami sterowania rozmytego dla elastycznie zautomatyzowanego wytwarzania.
PublicationPublikacja dotyczy struktury procesu produkcyjnego w środowisku komputerowo zintegrowanego wytwarzania (computer integrated manufacturing - CIM). Ukazuje ona aspekty kontroli jakości wykonania części na różnych etapach procesu wytwórczego, podkreślając jego istotność. W celu dokonania szczegółowej analizy problemu zebrano dane o jakości wykonania części na poszczególnych poziomach wytwarzania. Analizy dowiodły, że jakość wykonania...
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Various approaches to a human preference analysis in a digital signage display design
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The Effect of Cryogenic Treatment on Microstructure and Mechanical Response of AISI D3 Tool Steel Punches
PublicationRecently, deep cryogenic treatment is performed to improve the mechanical responses (wear, hardness, fatigue, and thermal conductivity) of various steel components. Researchers have tried to evaluate the eco-friendly and nontoxic process to optimize the parameters. Cold-shearing punches used to manufacture various holes that undergo severe impact loading and wear in the metal forming process. This study concerns the effect of soaking...
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Effect of the absence of clear contractual conditions for the pur-chase of combined heat and power systems through public tenders
PublicationW artykule przedstawiono dyskusję konsekwencji stosowania różnych podejść do obliczeń kontraktowych parametrów technicznych zespołów kogeneracyjnych. Obliczenia te wykonywane są na potrzeby oferty przygotowywanej w związku z ogłoszeniem przetargu publicznego na zakup siłowni kogeneracyjnej. Brak precyzyjnych zasad określających warunk, i jakie należy przyjąć do wyznaczania parametrów kontraktowych zespołów kogeneracyjnych umożliwia...
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Research on Tool Temperature Dependence on Lapping Grains Size
PublicationCommonly used as a finishing operation, lapping has been used for achieving ultra-high finishes and close tolerances between mating pieces. Its carried out by applying loose abrasive grains between work and lap surfaces, and causing a relative motion between them resulting in a finish of multi-directional lay. The grains activity (sliding and rolling) in the working gap causes not only the material removal but also the temperature...
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Rubber wastes recycling for developing advanced polymer composites: A warm handshake with sustainability
PublicationRecycling and management of rubber wastes experiences an early-stage maturity in the quest for sustainable and circular materials. Up to now, solutions proposed for sustainable development of rubber wastes are limited, so that properties and performance features of recycled products are inadequate for practical applications. Herein, an experimental protocol is introduced for manufacturing semi-sustainable polymer composites based...
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Golden artefacts, resin figurines, body adhesives and tomb sediments from the pre-Columbian burial site El Caño (Gran Coclé, Panamá): tracing organic contents using molecular archaeometry
PublicationThis research aimed to determine the origin of organic residues from funerary contexts in the El Ca~no settlement (Gran Cocl�e area, Panam�a, Central America) by means of multiple molecular probing techniques (GC-MS of organic solvent extracts and pyrolysis-GC-MS, THM-GC-MS and FTIR of solid samples). The samples include particles of precious resin figurines, fillings of golden objects, tomb sediments, plant exudates from extant...
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The dose-dependet influence of zinc and cadmium contamination of soil on their uptake and glucosinolate content in white cabbage (Brassica oleracea var. capitata f. alba)
PublicationThe relationship between the ability to accumulate heavy metals (represented by Cd and Zn) and to synthesize bioactive compounds (represented by glucosinolates[GLS]) was investigated in two cabbage cultivars. Plants were grown in the greenhouse of a phytotron under controlled conditions in soils spiked with two different Zn or Cd concentrations. The measurements of Cd and Zn contents in soil and cabbage (leaf) samples were performed...