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Search results for: RINGI
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Development of Sulfamoylated 4‑(1-Phenyl‑1H‑1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer
PublicationWe present here the advances achieved in the development of new sulfamoylated 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives as potent steroid sulfatase (STS) inhibitors for the treatment of breast cancer. Prompted by promising biological results and in silico analysis, the initial series of similar compounds were extended, appending a variety of m-substituents at the outer phenyl ring. The inhibition profiles of the newly...
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Operational problems of large power diesel engines combusting biofuels, considered togetherwith assessment of their operation
PublicationWithin this article the issue of large power self ignition engines fed with biofuels has been undertaken. The analysis focused mainly on operation problems. There has been noticed some advantages and difficulties associated with the biofuel application to self ignition engines. The research problem has been characterised and the research purposes have been proposed enabling the most profitable formation of energetic features of...
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Rekrutacja na studia – zachęcanie i stawianie wymagań
PublicationRekrutacja i utrzymanie na uczelni studentów, zwłaszcza tych dobrych, stanowi dziś dla wielu szkół wyższych wyzwanie nie mniejsze niż zagadnienia związane ze wzrostem poziomu naukowego nauczycieli akademickich czy kreowaniem pozytywnego wizerunku uczelni. Problemy z naborem urastają do rangi zagadnienia o znaczeniu strategicznym dla rozwoju szkół. Uczelnie chcą zwiększyć swoją efektywność i konkurencyjność na rynku edukacyjnym,...
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Non-destructive Testing of Wooden Elements
PublicationExamining the condition of wooden elements is crucial from the perspective of proper structure performance. If the deterioration in the internal wood condition, which displays no symptoms visible from the outside, is detected, the further spread of the deterioration can be prevented. Test results often point to the necessity of conducting repairs and, renovations, replacing the structure of wooden beams, or even substituting a...
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Safety integrity level verification for safety-related functions with security aspects
PublicationThe article is devoted some important issues of the functional safety analysis, in particular the safetyintegrity level (SIL) verification of safety functions to be implemented within the distributed controland protection systems with regard to cyber security aspects. The procedure for functional safety man-agement includes hazard identification, risk analysis and assessment, specification of overall safetyrequirements and definition...
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Kluczowe kompetencje jako narzędzie do tworzenia nowych modeli biznesu w przedsiębiorstwach
PublicationKoncepcja kluczowych kompetencji wywodzi się z nurtu zasobowego, który zakłada, iż o efektywności i konkurencyjności każdego podmiotu decydują odpowiednio dobrane zasoby i umiejętności ich optymalnego wykorzystania. Model biznesu to narzędzie do realizacji strategii organizacji, które wspomaga rozwój oraz zarządzanie strategiczne w przedsiębiorstwie. Dysertacja wypełnia lukę, jaką było wskazanie na zależność pomiędzy kluczowymi...
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Structure and properties of the exopolysaccharides produced by Pseudomonas mutabilis T6 and P. mutabilis ATCC 31014
PublicationThis paper presents a study on the purification, primary structure, and rheological properties of exopolysaccharides isolated from cultures of Pseudomonas mutabilis T6 and P. mutabilis ATCC 31014. Both polymers are exopolysaccharides of D-mannose. The mannan isolated from P. mutabilis T6 contains on average about 5% of residual b-D-glucose, in contrast to the mannan from P. mutabilis ATCC 31014, which contained only trace amounts...
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Quinoline-based thiazolyl-hydrazones target cancer cells through autophagy inhibition
PublicationHeterocyclic pharmacophores such as thiazole and quinoline rings have a significant role in medicinal chemistry. They are considered privileged structures since they constitute several Food and Drug Administration (FDA)-approved drugs for cancer treatment. Herein, we report the synthesis, in silico evaluation of the ADMET profiles, and in vitro investigation of the anticancer activity of a series of novel thiazolyl-hydrazones based...
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Copper(I) halide cluster-based coordination polymers modulated by chiral ditopic dithiodianthranilide ligands: synthesis, crystal structure and photoluminescence
PublicationReaction of copper(I) halides with chiral dithiodianthranilidesmdtaandbdtaafforded polymeric complexeswhere polynuclear CuX clusters were linked together by ditopic bridging ligands into 1D chains or 2D layerstructures. In the case of racemic ligands double stranded chain polymers were formed where the Cu4X4(X = I or Br) cores are connected by enantiomeric pairs of the ditopic ligands. In contrast, a homochiralmdtaligand created...
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Thermal and technological aspects of double face grinding of Al2O3 ceramic materials
PublicationDouble face grinding with planetary kinematics is a process to manufacture workpieces with plan parallel functional surfaces, such as bearing rings or sealing shims. In order to increase the economic efficiency of this process, it has to be advanced permanently. The temperature in the contact zone of most grinding processes has a huge influence on the process efficiency and the workpiece qualities. In contrast to most grinding...
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Deformation and Surface Color Changes of Beech and Oak Wood Lamellas Resulting from the Drying Process
PublicationThe drying process was examined relative to parameters’ influence on the deformation and surface layer color changes of beech wood (Fagus sylvatica L.) and oak wood (Quercus robur L.). The goal was to analyze the impact of drying process conditions, wood and growth rings types, and load on the deformation and surface color changes of drying thin wooden elements. A further aim was to reduce the time of the lamella drying and minimize...
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Polycyclic aromatic hydrocarbons as test probes to investigate the retention behavior of 1,3-alternate calix[4]arene silica-bonded stationary phases
PublicationA series of polycyclic aromatic hydrocarbons (PAHs) of different size and shape has been used to characterize the chromatographic behavior of five calix[4]arene stationary phases in 1,3-alternate conformation synthesized in our laboratory. The selection of linear, fourring nonlinear, and five-ring PAHs gave data on selectivity changes across range of the calix[4]arene columns. Retention of the 12 aromatic solutes has been evaluated...
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Biosynthetic and synthetic access to amino sugars.
PublicationAmino sugars are important constituents of a number of biomacromolecules and products of mi crobial secondary metabolism, including antibiotics. For most of them, the amino group is located at the positions C1, C2 or C3 of the hexose or pentose ring. In biological systems, amino sugars are formed due to the catalytic activity of specific aminotransferases or amidotransferases by introducing an amino functionality derived from L-glutamate...
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Applicability of phenolic acids as effective enhancers of cocrystals solubility of methylxanthines
PublicationApplicability of phenolic acids as potential cocrystal formers for methylxanthine derivatives was analyzed both in terms of cocrystallization probabilities and solubility advantage. The cocrystal formation abilities were evaluated using mixing enthalpy estimated within the conductor like screening model for real solvents (COSMO-RS) framework. The solubility improvement of potential cocrystals was estimated by formulation of the...
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Control of the wind turbine generator
PublicationWind power system consists of two main parts: wind turbine and electrical generator. Wind turbine converts the energy of the flowing air into mechanical energy, next generator converts this energy into electrical energy that is sent to the power system. These two processes should be realized with maximum efficiency and the following requirements for the control system can be formulated: opti-mal wind power conversion, compensation...
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Solid Phase Synthesis and Biological Activity of Tuftsin Conjugates
PublicationNew tuftsin/retro-tuftsin conjugates were designed and synthesized using a classical fluorenylmethoxycarbonyl (Fmoc) solid phase procedure. All the peptide conjugates were divided into three series: 1,4-dihydroxyanthraquinone (type A), 1-nitroacridine (type B), and 4-carboxyacridone (type C) derivatives. In type A conjugates, the N-terminal group of the peptide chain is directly connected to the anthraquinone ring at C1 (Scheme...
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On Reduced-Cost Design-Oriented Constrained Surrogate Modeling of Antenna Structures
PublicationDesign of contemporary antenna structures heavily relies on full-wave electromagnetic (EM) simulation models. Such models are essential to ensure reliability of evaluating antenna characteristics, yet, they are computationally expensive and therefore unsuitable for handling tasks that require multiple analyses, e.g., parametric optimization. The cost issue can be alleviated by using fast surrogate models. Conventional data-driven...
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3D Vision System for a Robotic Arm Based on Equal Baseline Camera Array
PublicationThis paper presents a lightweight 3D vision system called Equal Baseline Camera Array (EBCA). EBCA can work in different light conditions and it can be applied for measuring large range of distances. The system is a useful alternative to other known distance measuring devices such as structured-light 3D scanners, time-of-flight cameras, Light Detection and Ranging (LIDAR) devices and structure from motion techniques. EBCA can be...
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Improving Accuracy of Respiratory Rate Estimation by Restoring High Resolution Features With Transformers and Recursive Convolutional Models
PublicationNon-contact evaluation of vital signs has been becoming increasingly important, especially in light of the COVID- 19 pandemic, which is causing the whole world to examine people’s interactions in public places at a scale never seen before. However, evaluating one’s vital signs can be a relatively complex procedure, which requires both time and physical contact between examiner and examinee. These re- quirements limit the number...
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Photochemical Rearrangement of a 19-Membered Azoxybenzocrown: Products and their Properties
PublicationThe preparation and characterization of products of the chemical and photochemical rearrangements of a 19-membered o,o'-azoxybenzocrown were presented. In photochemical rearrangement, besides expected product i.e. 19-membered o-hydroxy-o,o'-azobenzocrown (19-o-OH), obtained under defined conditions with 75% yield, also other macrocyclic products were isolated and identified, namely: 19-membered p-hydroxy-o,o'-azobenzocrown (19-p-OH),...
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DIAMENTY JAKO PRZYKŁAD INWESTYCJI ALTERNATYWNEJ
PublicationW artykule scharakteryzowano determinanty decydujące o powodzeniu inwestycji w diamenty. Cel artykułu to zbadanie, jak masa, czystość, szlif, kolor, jednostka certyfikująca i kształt wpływają na cenę diamentu. Aby określić wpływ tych cech na cenę diamentu, zbudowano pięć modeli ekonometrycznych. Dla realizacji postawionego celu badawczego wykorzystano charakterystyki dla ponad 265 tysięcy diamentów. W wyniku przeprowadzonej analizy...
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The Impact of Drying Conditions on the Surface Color Changes of Pine Wood
PublicationThe article presents the impact of drying process and selected parameters on the color changes on the surface of pine wood (Pinus sylvestris L.). Three predetermined process conditions (modes), mild, normal, and intensive, were investigated. The experiments were conducted using a semi-industrial scale dryer designed at the Gdańsk University of Technology with a loading capacity of 0.55 m3. The drying process was applied to pine...
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Experimental and theoretical investigation of conformational states and noncovalent interactions in crystalline sulfonamides with a methoxyphenyl moiety
PublicationFour sulfonamide derivatives with a methoxyphenyl moiety, namely N-{4-[(2-methoxyphenyl)sulfamoyl] phenyl}acetamide (1a), N-{4-[(3-methoxyphenyl)sulfamoyl]phenyl}acetamide (1b), 4-amino-N-(2- methoxyphenyl)benzenesulfonamide (2a) and 4-amino-N-(3-methoxyphenyl)benzenesulfonamide (2b), have been synthesized and characterized physiochemically by CHNS, MS, FT-IR, 1H NMR, 13C NMR, PXRD and TG methods. Crystal structures were determined...
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Thermal Transitions and Structural Characteristics of Poly(3,4-ethylenedioxythiophene/cucurbit[7]uril) Polypseudorotaxane and Polyrotaxane Thin Films
PublicationHerein, we report the thermal transitions and structural properties of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril) pseudopolyrotaxane (PEDOT∙CB7-PS) and polyrotaxane (PEDOT∙CB7-PR) thin films compared with those of pristine PEDOT. The structural characteristics were investigated by using variable-temperature spectroscopic ellipsometry (VTSE), differential scanning calorimetry (DSC), X-ray diffraction (XRD) and atomic force...
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Sensitive simultaneous determination of 19 fluorobenzoic acids in saline waters by solid-phase extraction and liquid chromatography–tandem mass spectrometry
PublicationA solid-phase extraction (SPE) procedure using C18 stationary phase was optimized for the preconcentration of 19 fluorinated derivatives of benzoic acid (FBA): mono-, di-, tri-, and tetrafluorosubstituted in the ring, trifluoromethylbenzoic acid and 3,5-bistrifluoromethyl benzoic acid from undiluted salt-rich (>20%) reservoir waters. Quantitative (>90%) retention/elution of 16 out of 19 analyte compounds was achieved allowing a...
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Common methods for the chiral determination of amphetamine and related compounds II: Capillary electrophoresis and nuclear magnetic resonance
PublicationAmphetamine group and related ring-substituted substances are generally synthetic compounds, belonging to one of the most heavily abused drug groups in recent years. Some compounds in this class also originate from plants. Analysis of the enantiomers of AM-type compounds and metabolites is extremely important for a number of scientific disciplines. From studies of biological activity or mechanisms through determination of precursor...
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Novel Complementary Resonator for Dielectric Characterization of Substrates Based on Permittivity and Thickness
PublicationThis paper presents a novel complementary resonator featuring high sensitivity, low fabrication cost, and improved performance. The proposed structure consists of a complementary concentric square and circular ring resonator (CCSCRR) with multiple splits to enhance the inductance of the resonator. The proposed CCSCRR is coupled to a microstrip transmission line with an impedance of fifty ohms to create a high-sensitivity sensor....
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The influence of the type of halogen substituent and its position on the molecular conformation, intermolecular interactions and crystal packing for a series of 1-benzoyl-3-(halogenophenyl)thioureas
PublicationBy the reaction of benzoyl chloride, potassium isothiocyanate and the appropriate halogenoaniline, i.e. 2/3/4-(bromo/iodo)aniline, we have obtained five new 1-benzoyl-3-(halogenophenyl)thioureas, namely, 1-benzoyl-3-(2-bromophenyl)- thiourea and 1-benzoyl-3-(3-bromophenyl)thiourea, C14H11BrN2OS, and 1-benzoyl-3-(2-iodophenyl)thiourea, 1-benzoyl-3-(3-iodophenyl)thiourea and 1-benzoyl-3-(4-iodophenyl)thiourea, C14H11IN2OS. Structural...
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Multifunctional Bandpass Filter/Displacement Sensor Component
PublicationThis paper presents the design and realization of a multifunctional bandpassfilter/displacement-sensor using an edge-coupled microstrip bandpass filter loaded by a pair of split ring resonators (SRRs). It is shown that while the structure acts as a bandpass filter at its operating frequency, the phase of the reflection coefficient from a movable loading resonator at the resonance frequency of the resonator can be used for displacement...
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Novel complexes possessing Hg–(Cl, Br, I)⋯O=C halogen bonding and unusual Hg₂S₂(Br/I)₄ kernel. The usefulness of τ₄′ structural parameter
PublicationOne mononuclear and two binuclear Hg(II) complexes have been synthesized and characterized by X-ray diffraction, ATR IR and Hirshfeld surface analysis. Single-crystal X-ray diffraction showed that binuclear compounds are centrosymmetric and isostructural. All complexes form bifurcated intermolecular N–H···O hydrogen bonds that contribute to a formation of the centrosymmetric dimers. In binuclear complexes, sulfur atoms of thiourea...
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Modifications at the C(5) position of pyrimidine nucleosides
PublicationThis review summarizes the state of knowledge on the chemical methods of C(5)-modifications of uridine and cytidine derivatives and may serve as a useful tool for synthetic chemists to choose an appropriate reaction protocol. The synthesis of 5-substituted uracil derivatives is gaining an increasing interest because of their possible applications in medicine and pharmacy. Modifications at the C(5) position of pyrimidine nucleosides...
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The oil film parameters of the wankel engine apex seal in aspects of durability of mating elements
PublicationThe Wankel engine is one of only few alternatives to the reciprocating engines. The advantages such as good value of maximum engine power to its mass ratio are still present and can have great sense in selected fields of application, for example General Aviation. Nevertheless the disadvantages of the Wankel engine design have never lost its importance and still pose an obstacle to wider use of the Wankel engine. One of the main...
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Metodyka badań rozwojowych nowego typu silników i pomp satelitowych
PublicationResearch and development of new type satellite motors and satellite pumps SM with small geometrical displacement, from 5 to 73 cm3/rev, has been conducted in cooperation with Stosowanie Maszyn company from Katowice (manufacturer of motors and pump SM). The improvement of construction of those machines, especially construction of axial compensation and construction of fluid distribution channels have been the main problem of research...
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Influence and development of new kinematic systems in flat surface lapping
PublicationThe face grinding and lapping technology is widely used in the field of the precise and ultraprecise manufacturing. It has become an indispensable technology in the manufacture of many parts. An absence of material restrictions allows machining both metal and non-metallic materials, including technical ceramics [1]. Nowadays there are mainly two kinematic systems in lapping machines [2]. The machining plane-parallel surfaces is...
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ELEMENTY ZARZĄDZANIA OPERACYJNEGO RUCHEM DROGOWYM W MIASTACH
PublicationZwiększenie rangi zarządzania operacyjnego wynika z nacisków na szeroko rozumianą jakość, ciągłe doskonalenie oraz postrzegania organizacji jako takiej, która może odnieść sukces tylko wtedy, gdy wytwarza produkty, których oczekują klienci. Również w przypadku zarządzania ruchem drogowym w miastach zagadnienie zarządzania operacyjnego nabiera coraz większego znaczenia, gdyż każdy zarządzający ruchem powinien dostarczać produkt...
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The Mechanism of a Retro-Diels–Alder Fragmentation of Luteolin: Theoretical Studies Supported by Electrospray Ionization Tandem Mass Spectrometry Results
PublicationThe mechanisms of retro-Diels–Alder fragmentation of luteolin are studied theoretically using the Density Functional Theory method (B3LYP hybrid functional) together with the 6-311++G(d,p) basis set and supported by electrospray ionization tandem mass spectrometry (ESI-MS) results. The reaction paths leading to the formation of 1,3A and 1,3B fragment ions observed as the main spectral features in the ESI-MS spectrum are described...
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The influence oil additives on spread cracks in silicon nitride
PublicationThe paper presents an experimental study of the influence of oil additives (Cl, S, P, cerium dioxide (CeO2)) on spread cracks in silicon nitride. The additives Cl, S, P are bound in molecules in liquid form soluble in the base oil. The CeO2 is purely in powder form in suspension. The use of CeO2 powder was made based on the good results of polishing of silicon nitride. A ceramic angular contact ball bearing was modelled using a...
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How acidic amino acid residues facilitate DNA target site selection
PublicationDespite the negative charge of the DNA backbone, acidic residues (Asp/Glu) commonly participate in the base readout, with a strong preference for cytosine. In fact, in the solved DNA/protein structures, cytosine is recognized almost exclusively by Asp/Glu through a direct hydrogen bond, while at the same time, adenine, regardless of its amino group, shows no propensity for Asp/Glu. Here, we analyzed the contribution of Asp/Glu...
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Preparation of Well-Compatibilized PP/PC Blends and Foams Thereof
PublicationThe performance of polypropylene-poly(ethylene brassylate) block and graft copolymers and a polypropylene-polycaprolactone graft copolymer as compatibilizers for polypropylene-rich polypropylene/bisphenol A polycarbonate (PP/PC, 80/20 wt/wt) blends was elucidated. The copolymers were synthesized either by metal-catalyzed ring-opening polymerization or transesterification of a presynthesized polyester, initiated by hydroxyl-functionalized...
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Shape Memory Alloy-Based Fluidically Reconfigurable Metasurfaced Beam Steering Antenna
PublicationA low-cost actuator-based fluidically programmable metasurface (FPMS) antenna is proposed to solve the slow tuning speed problem of the manually fluidic based reconfigurable antennas. The FPMS-based antenna is probe-fed and comprises a 4 × 4 square ring metasurface as a superstrate. Moreover, two shape memory alloy (SMA)-based electrically-controlled actuators are employed in the design for controlling the position of the 3D-printed...
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Cross sections for electron collision with pyridine [C5H5N] molecule
PublicationThe absolute grand -total cross section (TCS) for electron scattering from pyridine, C5H5N, molecules has been measured at impact energies from 0.6 to 300 eV in the linear electron-transmission experiment. The obtained TCS energy dependence appears to be typical for targets of high electric-dipole moment; the cross section generally decreases with rising energy, except for the 3–20 eV range, where a broad enhancement peaked near...
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Analysing the impact of traffic incidents on express road traffic flow using FREEVAL
PublicationTraffic incidents occurring on motorways or express roads cause disruptions and deteriorate traffic conditions. The impact will differ depending on the type of incident, its duration and space blocked on the roadway and can be measured with e.g. average speed reduction, extension of travel time, time lost or overall costs of traffic disruptions. The aim of the paper is to analyse this impact, based on data from the Tri-City Ring...
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A Microwave Sensor with Operating Band Selection to Detect Rotation and Proximity in the Rapid Prototyping Industry
PublicationThis paper presents a novel sensor for detecting and measuring angular rotation and proximity, intended for rapid prototyping machines. The sensor is based on a complementary split-ring resonator (CSRR) driven by a conductor-backed coplanar waveguide. The sensor has a planar topology, which makes it simple and cost-effective to produce and accurate in measuring both physical quantities. The sensor has two components, a rotor, and...
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Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent
PublicationCarbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental methods were used, e.g., potentiometric, spectroscopic (ATR, UV, XRD powder,1H and13C NMR), electrochemical (cyclic voltammetry), and...
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Novel Biomass-Based Polymers: Synthesis, Characterization, and Application
PublicationA wide range of polymers were prepared from biomass-derivatives, using different polymerization mechanisms. Well-defined, fully hydroxy-functional polyesters based on aliphatic diols were synthesized, using either conventional metal-based catalysts or the organic superbase 1,5,7-triazabicyclododecene (TBD). Unsaturated polyesters were also made, offering additional functionality to these biobased resins. Metal-catalyzed or enzymatic...
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Design and synthesis of TiO2/Ti3C2 composites for highly efficient photocatalytic removal of acetaminophen: The relationships between synthesis parameters, physicochemical properties, and photocatalytic activity
PublicationIn this study, we report the potential of TiO2/Ti3C2 composite fabricated by oxidation of MXene for degradation of persistent organic pollutants. The effect of the synthesis conditions (time, temperature, and reaction environment) on the morphology, physicochemical properties, and photocatalytic activity was investigated. It was found that acetaminophen degradation was positively correlated with TiO2 content in the composite structure. Furthermore,...
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Performance-driven yield optimization of high-frequency structures by kriging surrogates
PublicationUncertainty quantification is an important aspect of engineering design, as manufacturing toler-ances may affect the characteristics of the structure. Therefore, quantification of these effects is in-dispensable for adequate assessment of the design quality. Toward this end, statistical analysis is performed, for reliability reasons, using full-wave electromagnetic (EM) simulations. Still, the computational expenditures associated...
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Toward Polyethylene–Polyester Block and Graft Copolymers with Tunable Polarity
PublicationThe synthesis and characterization of polyethylene–polyester block and graft copolymers and their potential as compatibilizers in polyethylene-based polymer blends are being described. The various routes to functionalized polyethylenes and the corresponding block/graft copolymers have been compared and evaluated for their scalability to industrial scale production. Hydroxyl chain-end and randomly OH-functionalized HDPE as well...
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Electroactive polymer/graphene oxide nanostructured composites; evidence for direct chemical interactions between PEDOT and GOx
PublicationThis work concerns electrochemical synthesis of nanocomposites consisting of conducting polymer and reduced graphene oxide (rGOx) as electrode materials for supercapacitors. The electrosynthesis was performed in an aqueous solution of the 3,4-ethylenedioxytiophene (EDOT) monomer and graphene oxide (GOx) without supporting electrolyte. The amount of GOx was optimized to obtain the best electrochemical performance of the nanocomposite...
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Spin-Resolved Band Structure of Hoffman Clathrate [Fe(pz)2Pt(CN)4] as an Essential Tool to Predict Optical Spectra of Metal–Organic Frameworks
PublicationParamount spin-crossover properties of the 3D-Hoffman metalorganic framework (MOF) [Fe(pz)2Pt(CN)4] are generally described on the basis of the ligand field theory, which provides adequate insight into theoretical and simulation analysis of spintronic complexes. However, the ligand field approximation does not take into account the 3D periodicity of the actual complex lattice and surface effects and therefore cannot predict a full-scale...