Search results for: bpcs
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Genetic diversity of Legionella pcs and pmtA genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines
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Exposure to Bisphenol A Analogs and the Thyroid Function and Volume in Women of Reproductive Age—Cross-Sectional Study
PublicationBisphenols (BPs) are commonly known plastifiers that are widely used in industry. The knowledge about the impact of BPs on thyroid function is scarce. Proper thyroid functioning is especially important for women of reproductive age, as hypothyroidism affects fertility, pregnancy outcomes and the offspring. There are no studies analyzing the influence of BPs on thyroid function and volume in non-pregnant young women. The aim of...
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Single-pill combinations (SPCs) and treatment of arterial hypertension in Poland. Expert consensus statement of the Polish Society of Hypertension and Polish Cardiac Society Working Group on Cardiovascular Pharmacotherapy
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Bisphenol A analogues and metabolic syndrome in women with polycystic ovary syndrome
PublicationBisphenols (BPs) have become a chemical group of special interest due to their ability to interfere with the endocrine system and their ubiquitous presence in the environment. As some of them possess mild estrogenic and anti-androgenic effects, they might be associated with the diagnosis of polycystic ovary syndrome (PCOS). Acting on multiple tissues, BPs exposure may lead to metabolic derangements characteristic for metabolic...
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Analiza niezawodności człowieka z uwzględnieniem aspektów zarządzania alarmami
PublicationW artykule przedstawiono zagadnienie analizy warstwowego systemu zabezpieczeń z uwzględnieniem błędu człowieka-operatora. W analizie bezpieczeństwa funkcjonalnego systemów sterowania i zabezpieczeń istotną kwestią jest dokonanie redukcji ryzyka poprzez warstwy zabezpieczeniowo ochronne. W referacie przeanalizowano system składający się z trzech warstw: podstawowego systemu sterowania BPCS, systemu alarmowego AS oraz systemu automatyki...
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Current issues of functional safety and cybersecurity analysis of the industrial and critical infrastructures
PublicationThis article addresses some functional safety assessment procedures with cybersecurity aspects in critical industrial installations with regard to the functional safety requirements specified in standards IEC 61508 and IEC 61511. The functional safety management includes hazard identification, risk analysis and assessment, specification of overall safety requirements and definition of safety functions. Based on the risk assessment...
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Procedure based proactive functional safety management for the risk mitigation of hazardous events in the oil port installations including insurance aspects
PublicationThis article addresses selected technical and organization aspects of risk mitigation in the oil port installations with regard to functional safety requirements specified in standards IEC 61508 and IEC 61511. The procedure for functional safety management includes the hazard identification, risk analysis and assessment, specification of overall safety requirements and definition of safety functions. Based on risk assessment results...
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Low-Cost Automated Design of Compact Branch-Line Couplers
PublicationBranch-line couplers (BLCs) are important components of wireless communication systems. Conventional BLCs are often characterized by large footprints which make miniaturization an important prerequisite for their application in modern devices. State-of-the-art approaches to design of compact BLCs are largely based on the use of high-permittivity substrates and multi-layer topologies. Alternative methods involve replacement of transmission-line...
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Safety integrity level verification for safety-related functions with security aspects
PublicationThe article is devoted some important issues of the functional safety analysis, in particular the safetyintegrity level (SIL) verification of safety functions to be implemented within the distributed controland protection systems with regard to cyber security aspects. The procedure for functional safety man-agement includes hazard identification, risk analysis and assessment, specification of overall safetyrequirements and definition...
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Electrostatic interactions in finite systems treated with periodic boundary conditions: Application to linear-scaling density functional theory
PublicationWe present a comparison of methods for treating the electrostatic interactions of finite, isolated systems within periodic boundary conditions (PBCs), within density functional theory (DFT), with particular emphasis on linear-scaling (LS) DFT. Often, PBCs are not physically realistic but are an unavoidable consequence of the choice of basis set and the efficacy of using Fourier transforms to compute the Hartree potential. In such...
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Optimization of a Fabric Phase Sorptive Extraction protocol for the isolation of six bisphenols from juice pouches to be analysed by high performance liquid chromatography coupled with diode array detector
PublicationFabric Phase Sorptive Extraction (FPSE) combined with high pressure liquid chromatography using to diode array detection (HPLC-DAD) was applied for the simultaneous determination of bisphenols (BPA, BPB, BPC, BPE, BPF, BPS) in juice pouches. The FPSE procedure was optimized with regards to the critical parameters that affect the performance of the method including the selection of the FPSE membrane type and size, adsorption time,...
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ANFIS-Based NPC Population Control in Video Games
PublicationModern computer games aim at providing rich, vivid worlds. The aim is to encourage the player to explore and interact with the in-game world. To describe the complex relations between in-game NPCs and their surrounding fuzzy logic is used. The paper presents ANFIS based population control in the video game. We present an approach allowing stabilizing the number of NPCs in-game by providing a certain amount of food to the environment....
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Human reliability analysis in the context of accident scenarios
PublicationArtykuł przedstawia problematykę analizy niezawodności człowieka (HRA) w kontekście zidentyfikowanych scenariuszy awaryjnych. Podkreślono potrzebę kontekstowej analizy postępowania człowieka-operatora ze szczególnym uwzględnieniem błędów i uszkodzeń zależnych w rozważanych scenariuszach awaryjnych. Analizę bezpieczeństwa funkcjonalnego z uwzględnieniem oceny niezawodności człowieka zilustrowano na przykładzie warstw zabezpieczeń...
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Solar light driven degradation of textile dye contaminants for wastewater treatment – studies of novel polycationic selenide photocatalyst and process optimization by response surface methodology desirability factor
PublicationThe unplanned anthropogenic activities and raced industrial revolution detrimentally causes serious threat to terrestrial and aquatic life. A high discharge of wastewater from industries using dyes affects living organisms and the environment. This paper presents studies on polycationic selenides (PCS) synthesized by hydrothermal methods for photocatalytic degradation of dyes. The synthesized PCS were confirmed by various characterization...
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METODA ANALIZY NIEZAWODNOŚCI CZŁOWIEKA SPAR-H W APLIKACJI ProSIL-EAL
PublicationW referacie przedstawiono zagadnienie wyznaczania prawdopodobieństwa błędu człowieka HEP za pomocą metody SPAR-H w oprogramowaniu ProSIL-EAL. Oprogramowanie wspomaga proces zarządzania bezpieczeństwem funkcjonalnym w cyklu życia systemów technicznych. Prawdopodobieństwo błędu człowieka jest zagadnieniem związanym z etapem weryfikacji określonych poziomów nienaruszalności bezpieczeństwa SIL dla funkcji bezpieczeństwa. ProSIL-EAL...
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Compact, Order Extensible and Wide-Stopband Bandpass Filter Based on SIW Cavity with Rectangular Ring Slot
PublicationThis article introduces novel architectures of bandpass filters (BPFs) using a substrate integrated waveguide (SIW) cavity with a rectangular ring slot (RRS) for compact size, extensible order, and broad stopband responses. Two bandpass filters, which demonstrate a second-and a fourth-order Chebyshev response, respectively, are realized by employing identical cavities with RRS, without increasing the physical size of the circuit....
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The effective elastic properties of human trabecular bone may be approximated using micro-finite element analyses of embedded volume elements.
PublicationBoundary conditions (BCs) and sample size affect the measured elastic properties of cancellous bone. Samples too small to be representative appear stiffer under kinematic uniform BCs (KUBCs) than under periodicity-compatible mixed uniform BCs (PMUBCs). To avoid those effects, we propose to determine the effective properties of trabecular bone using an embedded configuration. Cubic samples of various sizes (2.63, 5.29, 7.96, 10.58...
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Functional safety and human factors
PublicationRozdział przedstawia istotny problem uwzględnienia czynników ludzkich (H&OF) w analizie bezpieczeństwa funkcjonalnego, które wpływają istotnie na bezpieczeństwo przemysłowych obiektów podwyższonego ryzyka, nie ujęty jednak w normach bezpieczeństwa funkcjonalnego. Przedstawia się metody analizy niezawodności człowieka (HRA) w kontekście tych czynników, które wpływają na błędy człowieka. Czynniki ludzkie i organizacyjne powinny być...
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Designing issues of the alarm system in context of functional safety and human factors
PublicationThis article addresses selected aspects of the alarm system and human factors that should be evaluated during the design and operation of an industrial hazardous installation. In such installations the layer of protection analysis (LOPA) methodology is often applied for simplified risk analysis based on defined accident scenarios. To reduce and control the risks the safety instrumented functions (SIFs) are identified and their...
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Discussing daylight simulations in a proposal for online daylighting education.
PublicationThere is increasing interest concerning daylighting in the building sector. However, such knowledge is difficult to penetrate the curricula of architects and designers as existing educational programmes often do not provide sufficient training on BPS. This also leads to superficial use of daylight simulations. This paper presents a proposal for a needs-based education package on daylighting design, that mixes modular eLearning...
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Rapid design of miniaturised branch-line couplers through concurrent cell optimisation and surrogate-assisted fine-tuning
PublicationIn this study, the authors introduce a methodology for low-cost simulation-driven design optimisation of highly miniaturised branch-line couplers (BLCs). The first stage of their design approach exploits fast concurrent optimisation of geometrically dependent, but electromagnetically isolated cells that constitute a BLC. The cross-coupling effects between the cells are taken into account in the second stage, where a surrogate-assisted...
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Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE·2HCl in three component mixtures
PublicationEcosystems are facing increased pressure due to the emission of many classes of emerging contaminants. However, very little is known about the interactions of these pollutants, such as bisphenols (BPs), plasticizers or pharmaceuticals. By employing bioluminescent bacteria (Microtox assay), we were able to define interactions between selected emerging pollutants (namely BPA, BPS, BPF, BADGE, BADGE·2HCl, DEP, DBP) in ternary mixtures, at...
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Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
PublicationContaminants of emerging concern (CEC) localize in the biome in variable combinations of complex mixtures that are often environmentally persistent, bioaccumulate and biomagnify, prompting a need for extensive monitoring. Many cosmetics include UV filters that are listed as CECs, such as benzophenone derivatives (oxybenzone, OXYB), cinnamates (2-ethylhexyl 4-methoxycinnamate, EMC) and camphor derivatives (4-methylbenzylidene-camphor,...
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Safety Integrity Verification Issues of the Control Systems for Industrial Process Plants
PublicationThe aim of this article is to identify and discuss some issues that can be encountered in designing the industrial automation and control systems (IACS) for implementing safety functions. In a functional safety standard IEC 61511 for the process industry such systems are named the basic process control systems (BPCS) and the safety instrumented systems (SIS). In a generic functional safety standard IEC 61508 they are depicted as...
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OBTAINING OF COUMARONE-INDENE RESINS BASED ON LIGHT FRACTION OF COAL TAR 3. COUMARONE-INDENE RESINS WITH METHACRYLIC FRAGMENTS
PublicationThe method for obtaining coumarone-indene resins with methacrylic fragments (CIRM) was developed with the addition of methyl ethacrylate, using a light fraction of coal tar and its fraction boiling within 423–463 К. CIRM was obtained via radical cooligomerization using 2,2'-azobis (2-methyl-propionitrile) as the initiator. The effect of the initiator amount, temperature and reaction time on the yield, softening temperature and...
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Predicting Value of Binding Constants of Organic Ligands to Beta-Cyclodextrin: Application of MARSplines and Descriptors Encoded in SMILES String
PublicationThe quantitative structure–activity relationship (QSPR) model was formulated to quantify values of the binding constant (lnK) of a series of ligands to beta–cyclodextrin (β-CD). For this purpose, the multivariate adaptive regression splines (MARSplines) methodology was adopted with molecular descriptors derived from the simplified molecular input line entry specification (SMILES) strings. This approach allows discovery of regression...
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Warstwowy system zabezpieczeń w przemysłowych instalacjach podwyższonego ryzyka
PublicationRozdział poświęcono aktualnym zagadnieniom analizy i projektowania warstw zabezpieczeń w kontekście oceny ryzyka i zarządzania bezpieczeństwem funkcjonalnym w cyklu życia z wyróżnieniem trzech warstw: (1) podstawowego systemu sterowania BPCS (basic process control system), (2) człowieka-operatora korzystającego opcjonalnie z systemu alarmowego AS (alarm system) oraz (3) przyrządowego systemu bezpieczeństwa SIS (safety instrumented...
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Insights into modification of lignocellulosic fillers with isophorone diisocyanate: structure, thermal stability and volatile organic compounds emission assessment
PublicationThis study presents an analysis of the structure and properties of different types of lignocellulosic fillers modified by isophorone diisocyanate (IPDI) to provide insights into the possibility of their application to the manufacturing of wood polymer composites (WPCs). Moreover, it deals with the environmental aspects of modified fillers, by assessment of volatile organic compounds (VOCs) emitted during modification, as well as...
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WERYFIKACJA POZIOMÓW NIENARUSZALNOŚCI BEZPIECZEŃSTWA Z UWZGLĘDNIENIEM ASPEKTÓW OCHRONY INFORMACJI
PublicationPoszczególnym poziomom SIL projektowanego systemu elektrycznego/elektronicznego/programowalnego elektr onicznego E/E/PE (BPCS lub SIS) odpowiadają ilościowe kryteria probabilistyczne. Dowód spełnienia przez system zabezpieczeń wymagań SIL nazywa się weryfikacją. Model probabilistyczny dowolnego systemu zabezpieczeń SIS można przedstawić za pomocą schematów blokowych niezawodności RBD, grafów Markowa, równań uproszczonych oraz drzew niezdatności...
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Komputerowe wspomaganie procesu zarządzania bezpieczeństwem funkcjonalnym
PublicationW niniejszym rozdziale przedstawiono oprogramowanie ProSIL wspomagające zarządzanie bezpieczeństwem funkcjonalnym. Program ProSIL składa się z dwóch modułów wspomagających: określenie wymaganego poziomu SIL (moduł ProSILen) oraz weryfikację SIL (moduł ProSILer). W aplikacji ProSIL zaimplementowano opracowaną w trakcie badań metodykę analizy bezpieczeństwa funkcjonalnego w projektowaniu i użytkowaniu systemów SIS zgodnie z wymaganiami...
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Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds
PublicationBackground Epidermal progenitor cells (EPCs) have been under extensive investigation due to their increasing potential of application in medicine and biotechnology. Cultured human EPCs are used in the treatment of chronic wounds and have recently became a target for gene therapy and toxicological studies. One of the challenges in EPCs culture is to provide a high number of undifferentiated, progenitor cells displaying high viability...
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Bisphenols (A, S, and F) affect the basic hormonal activity determined for pharmaceuticals – Study of Saccharomyces cerevisiae
PublicationPharmaceuticals and analogs of bisphenol A (BPA) are increasingly threatening environmental pollutants. In this study, mixtures of selected pharmaceuticals (diclofenac sodium salt, chloramphenicol, oxytetracycline hydrochloride, fluoxetine hydrochloride, estrone, ketoprofen, progesterone, gemfibrozil and androstenedione) were prepared with BPA and its two analogs (namely, bisphenols F and S) at such ratios to reflect environmentally...
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Electronic structure calculations in electrolyte solutions: Methods for neutralization of extended charged interfaces
PublicationDensity functional theory (DFT) is often used for simulating extended materials such as infinite crystals or surfaces, under periodic boundary conditions (PBCs). In such calculations, when the simulation cell has non-zero charge, electrical neutrality has to be imposed, and this is often done via a uniform background charge of opposite sign (“jellium”). This artificial neutralization does not occur in reality, where a different...
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WPŁYW POZIOMU OCHRONY INFORMACJI NA WYMAGANIA NIENARUSZALNOŚCI BEZPIECZEŃSTWA
PublicationW referacie przedstawiono zagadnienia związane z etapem analizy i oceny ryzyka obiektu technicznego podwyższonego ryzyka. Opisano metody określania wymagań na nienaruszalność bezpieczeństwa SIL zidentyfikowanych funkcji bezpieczeństwa. Funkcje takie realizowane są przez systemy E/E/PE (BPCS i/lub SIS) i są częścią systemu bezpieczeństwa składającego się z wielu warstw zabezpieczeniowo-ochronnych. Zarówno w metodach jakościowych,...
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Optimized photodegradation of palm oil agroindustry waste effluent using multivalent manganese–modified black titanium dioxide
PublicationThis article presents a methodological approach to use manganese (Mn3+Mn7+)-modified black titanium dioxide (Mn/BTiO2) as a photocatalyst to optimize and improve visible-light-driven photodegradation of treated agro-industrial effluent (TPOME). A modified wet chemical process was used to prepare BTiO2. The BTiO2 was then wet impregnated with Mn and calcined at 300 °C for 1 h to produce Mn/BTiO2. The activity of Mn/BTiO2 was investigated...
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A novel approach in wood waste utilization for manufacturing of catalyst-free polyurethane-wood composites (PU-WC)
PublicationIn recent decades, due to the increase in environmental awareness and noticeable environmental degradation, the area of wood waste management has attracted increasing attention. The purpose of this study is to develop a new type of highly filled polyurethane wood-composite (PU-WC) by the utilization of large amount of wood wastes without addition of a catalyst. Although wood-plastic composites (WPCs) are widely known, there is...
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New Type of Small Broad-Band Internal Antenna for Third Generation Mobile Phone Handsets.
PublicationW pracy przedstawiono nową szerokopasmową antenę łatową przeznaczoną dla telefonów komórkowych trzeciej generacji. Proponowana struktura zawiera obwód (rezonator) w kształcie litery U i zaliczana jest do klasy PIFA (planar inverted-F antenna). W trakcie procesu projektowania przeprowadzono szereg symulacji elektromagnetycznych (metoda momentów), których wyniki zweryfikowano w oparciu o pomiary charakterystyk wykonanego prototypu....
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Miniaturized Dual-Band SIW-Based Bandpass Filters Using Open-Loop Ring Resonators
PublicationThis article presents two novel architectures of dual-band substrate integrated waveguide (SIW) bandpass filters (BPFs). Initially, two identical open-loop ring resonators (OLRRs) are coupled face-to-face on the top of the SIW cavity to realize a dual-band single-pole BPF. To obtain two-pole dual-band characteristics, two OLRRs resonant units are assembled horizontally within the top metal layer of the SIW, which is a technique...
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Inline Microwave Filters With N+1 Transmission Zeros Generated by Frequency-Variant Couplings: Coupling-Matrix-Based Synthesis and Design
PublicationA general coupling-matrix-based synthesis methodology for inline Nth-order microwave bandpass filters (BPFs) with frequency-variant reactive-type couplings that generate N+1 transmission zeros (TZs) is presented in this brief. The proposed approach exploits the formulation of the synthesis problem as three inverse nonlinear eigenvalue problems (INEVPs) so that the coupling matrix is built from their sets of eigenvalues. For this...
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Superconductivity in the niobium-rich compound Nb5Se4
PublicationThe niobium rich selenide compound Nb5Se4 was synthesized at ambient pressure by high-temperature solid–state reaction in a sealed Ta tube. Resistivity and heat capacity measurements reveal that this compound is superconducting, with a Tc = 1.85K. The electronic contribution to the specific heat γ and the Debye temperature are found to be 18.1 mJmol−1K−2 and 298 K respectively. The calculated electron-phonon coupling constant λep...
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Development of thin film SPME sorbents based on deep eutectic solvents and their application for isolation and preconcentration of endocrine-disrupting compounds leaching from diapers to urine
PublicationIn this study, the thin film solid phase microextraction (TF-SPME) based on a novel sorbent composed of deep eutectic solvent (DES) is proposed. Among several synthesized sorbents the most efficient was DES containing trihexyl(tetradecyl)phosphonium chloride and docosanol mixed with polydimethylsiloxane (PDMS) in a molar ratio 1:3:0.25 to achieve a more stable structure. The proposed sorbent was applied on a fiberglass mesh and...
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The electronic characterization of the cubic Laves-phase superconductor CaRh2
PublicationWe present the synthesis and experimental characterization of the electronic properties of the cubic Laves phase superconductor CaRh2. Its crystal structure was confirmed by powder X-ray diffraction and its ambient temperature lattice parameter (a = 7.5326(6) Å) is in good agreement with the literature. Magnetization, resistivity and heat-capacity measurements indicate that CaRh2 is a moderate-coupling type-II superconductor (λe-p = 0.89)...
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Towards β-selectivity in functional estrogen receptor antagonists
PublicationBased on the benzo[b]naphtho[1,2-d]furan and benzo[b]naphtho[1,2-d]thiophene frameworks, a series of ligands with different basic side chains (BSCs) has been synthesized and pharmacologically evaluated. Also, their binding modes have been modelled using docking techniques. It was found that the introduction of a BSC in these systems brings about a decrease of affinity for both estrogen receptors α and β in an in vitro competitive...
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Parallel computations in the volunteer based Comcute system
PublicationThe paper presents Comcute which is a novel multi-level implemen- tation of the volunteer based computing paradigm. Comcute was designed to let users donate the computing power of their PCs in a simplified manner, requiring only pointing their web browser at a specific web address and clicking a mouse. The server side appoints several servers to be in charge of execution of particular tasks. Thanks to that the system can survive...
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The σ-phase superconductors Nb20.4Rh5.7Ge3.9 and Nb20.4Rh5.7Si3.9
PublicationWe show that the previously unreported ternary σ phases Nb20.4Rh5.7Ge3.9 and Nb20.4Rh5.7Si3.9 are both superconductors with Tc values of approximately 1.9 K. The superconducting transitions were characterized through temperature-dependent magnetic susceptibility, electrical resistance, and specific heat measurements. The Sommerfeld constants, γ, for Nb20.4Rh5.7Ge3.9 and Nb20.4Rh5.7Si3.9 are 89(1) mJ mol-f.u.−1K−2 and 86(1) mJ mol-f.u.−1K−2...
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BREAST, Mammary gland - Female, 46 - Tissue image [5230730013278771]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 46 - Tissue image [523073001327921]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 46 - Tissue image [5230730013274751]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 46 - Tissue image [5230730013272421]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.
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BREAST, Mammary gland - Female, 46 - Tissue image [5230730013273651]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.