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Search results for: LYSINE AUXOTROPHY
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Novel molecules containing structural features of NSAIDs and 1,2,3-triazole ring: Design, synthesis and evaluation as potential cytotoxic agents
PublicationFor the first time the template containing structural features of more than one NSAIDs and the 1,2,3-triazole ring was explored for the identification of potential cytotoxic agents. These new and complex molecules were predicted to be effective inhibitors of PDE4B by molecular modelling studies in silico. The multi-step synthesis of these compounds were carried out starting from the well-known drug nimesulide and involved the use...
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Surrogate-assisted EM-driven miniaturization of wideband microwave couplers by means of co-simulation low-fidelity models
PublicationThis article proposes a methodology for rapid design optimization of miniaturized wideband couplers. More specifically, a class of circuits is considered, in which conventional transmission lines are replaced by their abbreviated counterparts referred to as slow-wave compact cells. Our focus is on explicit reduction of the structure size as well as on reducing the CPU cost of the design process. For the sake of computational feasibility,...
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In Vitro Studies on Nanoporous, Nanotubular and Nanosponge-Like Titania Coatings, with the Use of Adipose-Derived Stem Cells
PublicationIn vitro biological research on a group of amorphous titania coatings of different nanoarchitectures (nanoporous, nanotubular, and nanosponge-like) produced on the surface of Ti6Al4V alloy samples have been carried out, aimed at assessing their ability to interact with adipose-derived mesenchymal stem cells (ADSCs) and affect their activity. The attention has been drawn to the influence of surface coating architecture and its physicochemical...
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Mechanical and Microstructural Characterization of TIG Welded Dissimilar Joints between 304L Austenitic Stainless Steel and Incoloy 800HT Nickel Alloy
PublicationIn this article, the mechanical properties and microstructure of 304L austenitic stainless steel/Incoloy 800HT nickel alloy dissimilar welded joints are investigated. The joints were made of 21.3 mm × 7.47 mm tubes using the TIG process with the use of S Ni 6082 nickel filler metal. No welding imperfections were found and high strength properties of joints were obtained, meeting the assumed acceptance criteria of the product’s...
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Structure, Physicochemical and Biological Properties of an Aqua (2,2′,2′′-Nitrilotriacetato)-oxidovanadium(IV) Salt with 4-Methylpyridinium Cation
PublicationThe crystal structure of a nitrilotriacetate (nta) oxidovanadi-um(IV) salt with 4-methylpyridinium cation, [4-Me(Py)H]+, of [4-Me(Py)H][VO(nta)(H2O)] stoichiometry was determined. The com-plex comprises a discrete mononuclear [VO(nta)(H2O)]–coordinationentity that can be rarely found among other known compounds con-taining nitrilotriacetate oxidovanadium(IV) moieties. The complex wascharacterized by spectroscopic (IR and EPR) methods,...
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Investigation on polypropylene friction stir joint: effects of tool tilt angle on heat flux, material flow and defect formation
PublicationTool tilt angle (TTA) is a critical factor that can control material flow in polymeric materials' friction stir joining (FSJ). This study selected a TTA range between 0° to 4° for FSJ of polypropylene (PP) polymer sheet. A modified computational fluid dynamic (CFD) technique was implemented to gain a deep understanding of the effects of TTA during FSJ of PP. The PP joint's internal flow, defect formation, heat generation, and tensile...
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Modelowanie matematyczne górnej sieci trakcyjnej dla potrzeb diagnostyki odbieraków prądu
PublicationGórna sieć trakcyjna jest obecnie najbardziej skutecznym sposobem zasilania kolejowych pojazdów elektrycznych. Wzrost prędkości pojazdów zwiększa pobór mocy i wymaga zapewnienia właściwej współpracy odbieraków prądu pojazdów z siecią jezdną. Metody modelowania i projektowania wspomaganego komputerowo dla górnej sieci trakcyjnej są obecnie na całym świecie szeroko rozwijane. W artykule przedstawiono nowy model matematyczny elementów...
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Przedmiot wyrównawczy (Analityk danych, semestr zimowy 2022/2023)
e-Learning Coursesćwiczenia mgr inż. Michał Krzemiński Specjalność: Analityk danych, II stopnia, Matematyka, WFTiMS, stacjonarne, 2022/2023 - zimowy (obecnie sem. 1)
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Konsultacje 2022/23 ZIMA - KKI - Kowalski Dariusz
e-Learning CoursesKurs przeznaczony do prowadzenia wszelkiego rodzaju konsultacji / konsultacji dyplomowych / spotkań / zebrań projektowych itp. odbywających się za pomocą komunikacji elektronicznej z wykorzystaniem możliwości dostępnych w ramach PG. Kurs dostępny w godzinach konsultacji planowych dla bieżącej komunikacji ze studentami oraz dla umówionych spotkań z dyplomantami w semestrze zimowym 2022/2023. dr inż. Kowalski Dariusz Katedra...
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Seminarium dyplomowe 2023_sem 8
e-Learning CoursesSeminarium dyplomowe dotyczy zagadnień niezbędnych do opracowania projektu dyplomowego. Tematyka zajęć: Zasady sporządzania opisu technicznego (zakres w projekcie budowlanym a książeczka dyplomowa); Zagospodarowanie terenu (wytyczne wg normy, zakres, grubości linii itp. + przykładowe rysunki); Rzuty – zasady zapisu projektu budowlanego (wymiarowanie, grubości linii, stolarka, szrafy – wg normy, opisy itp. + przykładowe rysunki); Przekroje...
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Budowanie zaufania w relacjach interentowych
PublicationArtykuł prezentuje znaczenie zaufania w relacjach interpersonalnych oraz wpływ globalizacji na proces budowania i percepcji zaufania pomiędzy uczestnikami relacji społecznych. Przedstawiono badania własne, w których autorka zweryfikowała postawy badanych wobec zaufania w relacjach internetowych i poziom wiarygodności partnera w komunikacji odbywającej się z wykorzystaniem różnych internetowych funkcjonalności (forum internetowe,...
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Techniki śródoperacyjnego monitorowania EKG
PublicationZ badania EKG lekarze uzyskują szereg cennych informacji niezbędnych do prawidłowego podejmowanie ważnych decyzji terapeutycznych. EKG stało się pierwszym parametrem monitorowanym standardowo i w sposób ciągły podczas znieczulenia. Współczesna technika umożliwia nie tylko ciągłe monitorowanie zapisu EKG, a także transmisję danych on-line do dowolnego miejsca w szpitalu, i ich cyfrową rejestrację. Najistotniejszym kryterium przydatności...
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Economic benefits of dynamic charging of electric buses
PublicationDiesel engines buses are still the most used type of buses. Electric buses provide promising green alternatives and a lot of advantages, but their main disadvantages are limited travel range and long charging time. This article is a presentation of innovative solution for charging of electric busses - Dynamic Charging (IMC). The modern IMC system in Solingen was presented. At the end of the article, a proposal was made to introduce...
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An Approach to Mean Path Loss Model Estimation for Off-Body Channels
PublicationThis paper presents an approach to estimation of the mean path loss model parameters in off-body Body Area Networks channels. In this approach, the path loss exponent is constrained to a value obtained for the line-of-sight (LoS) propagation in the co-polarised channel, considering a generalised static scenario. The comparison of the goodness of fit between the proposed approach and other approaches, for a set of measurements obtained...
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A Noether theorem for stochastic operators on Schatten classes
PublicationWe prove that a stochastic (Markov) operator S acting on a Schatten class C_1 satisfies the Noether condition S'(A) = A and S'(A^2) = A^2, where A is a Hermitian bounded linear operator on a complex Hilbert space H, if and only if, S(E(G)XE(G)) = E(G)S(X)E(G) holds true for every Borel subset G of the real line R, where E(G) denotes the orthogonal projection coming from the spectral resolution of A. Similar results are obtained...
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Regulation of Cellular Redox Homeostasis by (–)-Epicatechin and Cocoa Extracts—A Pilot Study
PublicationCocoa polyphenols play an important role in protection against diseases in which oxidative stress is implicated as a causal or contributing factor. The main aim of this study was to elucidate the influence of different cocoa extracts and main cocoa bioactive compound (–)-epicatechin on cell growth and support of antioxidant cellular barrier in colon adenocarcinoma cell line model (HT29). Results show that the tested cocoa bioactivity...
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REGULATION OF CELLULAR REDOX HOMEOSTASIS BY (-)-EPICATECHIN AND COCOA EXTRACTS – PILOT STUDY
PublicationCocoa polyphenols play an important role in protection against diseases in which oxidative stress is implicated as a causal or contributing factor. The main aim of this study was to elucidate the influence of different cocoa extracts and main cocoa bioactive compound (–)-epicatechin on cell growth and support of antioxidant cellular barrier in colon adenocarcinoma cell line model (HT29). Results show that the tested cocoa bioactivity...
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Błędy cyfrowej rejestracji prędkości obrotowej z wykorzystaniem przetwornika obrotowo-impulsowego
PublicationPrzedstawiono zasadę działania przetwornika obrotowo-impulsowego w zastosowaniu do pomiaru prędkości obrotowej. Omówiono metody rejestracji on-line sygnału impulsowego z przetwornika obrotowo-impulsowego. W metodach tych prędkość obrotowa wyznaczana jest na podstawie ostatniego przedziału miedzyimpulsowego lub na podstawie dwóch ostatnich przedziałów miedzyimpulsowych z ekstrapolacji. Dla sinusoidalnej zmiany prędkości udowodniono,...
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Dynamic Positioning System with Vectorial Backstepping Controller
PublicationThe problem of synthesis a dynamic positioning system for low frequency model of surface vessel was considered in this paper. The recursive vectorial backstepping control design was used to keep a fixed position and heading in presence of wave disturbances. The passive observer was introduced to smooth the measurements and to estimate the velocities needed for the control algorithm. Some parameters of observer were optimized off-line...
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Synthesis and biological activity of mycophenolic acid-amino acid derivatives
PublicationIn search of new immunosuppressants, mycophenolic acid (MPA) was coupled with amino acid methyl esters followed by hydrolysis to analogs bearing free carboxylic groups. The obtained compunds were tested in vitro as growth inhibitors of lymphoid cell line (Jurkat) and human peripheral blood mononuclear cells (PBMC) from healthy donors. According to obtained results recovering of free carboxylic group increased their activity. Additionally,...
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Test Execution Logging and Visualization Techniques
PublicationTraditionally, log traces of test cases ex ecution are stored in textual format and their analysis is done in a post- execution phase. Our approach bases on the concept of gr aphical presentation of te st execution which enables better analysis of log traces and also gives the opportunity to consider them on-line. In particular, we discuss the graphical symbols we chose, we pres ent the logging interface we defined a nd describe...
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Elliptical slot UWB monopole antenna
PublicationThe UWB monopole antenna with elliptical radiating slot end and microstrip feeding line terminated with radial stub have been designed, fabricated and measured. The antenna show return loss less than -12 dB in the whole UWB bandwidth. Linearity of the reflection coefficient phase product have also been achieved. Radiation patterns of the antenna measured at three selected frequency points indicated regular, approximately omni directional...
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Reference FEM model for SHM system of cable-stayed bridge in Rzeszów
PublicationThe paper presents the references model for structural health monitoring system (SHM) of cable-stayed bridge recently constructed in Rzeszów over Wisłok River. The SHM system is design to provide on-line information on the structure state and facilitate its maintenance procedures. The main feature of the SHM system is permanent observation of the dynamic behavior of the bridge with focus on cable vibrations. The paper discusses...
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On the instantaneous frequency smoothing for signals with quasi-linear frequency changes
PublicationThe problem of estimation of the slowly-varying instantaneous frequency of a nonstationary complex sinusoidal signal buried in noise is considered. This problem is usually solved using frequency tracking algorithms. It is shown that the accuracy of frequency estimates can be considerably increased if the results yielded by the frequency tracker are further processed using the appropriately designed filters. The resulting frequency...
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A Point Set Connection Problem for Autonomous Mobile Robots in a Grid
PublicationConsider an orthogonal grid of streets and avenues in a Manhattan-like city populated by stationary sensor modules at some intersections and mobile robots that can serve as relays of information that the modules exchange, where both module-module and module-robot communication is limited to a straight line of sight within the grid. The robots are oblivious and move asynchronously. We present a distributed algorithm that, given...
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Cyfrowa wewnątrzsamolotowa magistrala komunikacyjna ARINC 429
PublicationW artykule przedstawiono standard cyfrowej magistrali komunikacyjnej ARINC 429 przeznaczonej do współpracy urządzeń na pokładzie samolotów. Skupiono się na warstwie fizycznej i protokolarnej tego standardu.
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Striking elements - A lifebelt or a fad? Searching for an effective way of adapting abandoned churches.
PublicationAre avant-garde elements added to historical objects as a temporary fashion to fulfill the aspirations of designers or an attempt to draw attention to themselves? It may be the exact opposite, and this type of controversial project is the best lifebelt for such monuments. This article explores issues related to external avant-garde elements added to adapted churches and their influence on the efficiency of such adaptation projects....
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GDAŃSK UNIVERSITY OF TECHNOLOGY - A CONTINUATOR OF THE LVIV SCHOOL OF ARCHITECTS' EDUCATION ON THE EXAMPLE OF DESCRIPTIVE GEOMETRY TEACHING
PublicationThe new theory at the time was descriptive geometry, quickly reached the Polish lands. Her first lecture was held at the Warsaw School of Artillery and Engineering in 1809-1812, by a French teacher Jan Joachim Livet (1809-12). The new discipline was quickly adopted in all major centers of Polish science at that time, which include university cities - Warsaw, Krakow, Vilnius and the Krzemienieckie High School, which represent high...
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The Use of Wavelet Analysis to Denoising of Electrocardiography Signal
PublicationThe electrocardiography examination, due to its accessibility and simplicity, has an important role in diagnostics of the heart ailments. It enables quick detection of various heart defects, undetectable by other kinds of diagnostic tools, so it is very popular. Nevertheless, the measured signal is exposed to a different disturbances. Among them, the electromagnetic interferences, drift of reference electrode and high frequency...
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Toxoplasma godnii recombinant chimeric antigens - IgM and IgG ELISAs - mouse serum samples
Open Research DataThis study presents an evaluation of tetravalent recombinant chimeric proteins containing fragments of the Toxoplasma gondii antigens, SAG2, SAG1, GRA1, GRA2, MIC1, MAG1, ROP1 and AMA1, as potential replacements of a the soluble, whole-cell tachyzoite lysate (TLA) used in serological assays. Recombinant chimeric proteins (SAG1-MIC1-MAG1-GRA2, SAG2-GRA1-ROP1-GRA2,...
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Toxoplasma gondii recombinant chimeric antigens - IgG and IgM ELISAs - human serum samples
Open Research DataThis study presents an evaluation of tetravalent recombinant chimeric proteins containing fragments of the Toxoplasma gondii antigens, SAG1, SAG2, GRA1, GRA2, MIC1, MAG1, ROP1 and AMA1, as potential replacements of a the soluble, whole-cell tachyzoite lysate (TLA) used in serological assays. Recombinant chimeric proteins (SAG1-MIC1-MAG1-GRA2, SAG2-GRA1-ROP1-GRA2,...
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Measurements and Measurement Systems [2022/23]
e-Learning CoursesOpis kursu: (np. numer semestru, dla którego przeznaczony jest kurs, cel lub tematyka przedmiotu) IV semestr kierunku Energy Technologies. Celem kursu jest zapoznanie teoretyczne i praktyczne studentów z podstawowymi i zaawansowanymi metodami pomiarowymi różnych wielkości pomiarowych oraz budową i zasadą działania systemów pomiarowych. The aim of the course is to introduce theoretical and practical students with basic...
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OCENA UZIEMIEŃ SŁUPÓW LINII ELEKTROENERGETYCZNYCH ZWŁASZCZA POSADOWIONYCH NA GRUNTACH O WYSOKIEJ REZYSTYWNOŚCI
PublicationW artykule została omówiona problematyka pomiaru i oceny właściwości uziemień słupów linii elektroenergetycznych z wykorzystaniem przebiegów wolno-i szybkozmiennych. Uzyskanie odpowiednio niskiej wartości rezystancji uziemienia słupa posadowionego na gruncie o rezystywności powyżej 1000Ωm może być trudne. Praca zawiera analizę zmian właściwości statycznych i udarowych uziemień w funkcji rezystywności...
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Low energy inelastic electron scattering from carbon monoxide: II. Excitation of the b3Σ+, j3Σ+, B1Σ+, C1Σ+ and E1Π Rydberg electronic states
PublicationIn this second part of a two part paper (first part: Zawadzki et al (2020 J. Phys. B: At. Mol. Opt. Phys. 53 165201)) we present differential scattering cross sections for excitation of several Rydberg electronic states of carbon monoxide by electron impact. The first part concerned the low-lying valence states of CO. In the present study cross sections are obtained experimentally using low-energy electron energy-loss spectroscopy...
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INFLUENCE OF TEMPERATURE ON THE ACTIVITY OF ANAMMOX GRANULAR BIOMASS - SHORT AND LONG-TERM ASPECT
PublicationThe aim of this study was to determine a short-term and long-term effect of temperature on the anammox process rate and determination of temperature coefficients in the Arrhenius and Ratkowski equations. The short-term effects of temperature on the anammox biomass were investigated in batch tests at ten different temperatures in the range of 10-55 ̊C. The maximum rate 1.3 gN (gVSS·d)-1 observed at 40 ̊C. The minimum rate, close...
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Myelodysplastic syndrome, NOS - Male, 65 - Tissue image [11290630017295671]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Myelodysplastic syndrome, NOS - Male, 65 - Tissue image [11290630017298631]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Myelodysplastic syndrome, NOS - Male, 65 - Tissue image [11290630017293721]
Open Research DataThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Lean Management Zima 2022 NST
e-Learning CoursesKurs Lean Management dla studentów studiów niestacjonarnych to 8h materiał teoretyczny on-line z mini zadaniami, którego istotnym rozwinięciem jest 16h ćwiczeń realizowanych w trybie stacjonarnym, czyli podczas naszych wspólnych zajęć. Celem materiału teoretycznego jest przybliżenie Wam tzw. WHY?, czyli przyczyn, dla których wiedza, którą będziemy Wam przekazywać i umiejętności, które zdobywać będziecie podczas ćwiczeń stanowią...
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NCN: Szkolenie dla wnioskodawców
EventsProgram szkolenia 18 listopada 2022: • Konkursy NCN / Konkursy międzynarodowe • Harmonogram konkursów • Przygotowanie wniosku • Procedura oceny wniosku • Rozliczanie projektów
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Experience marketing in the service of the “secular religion” of big tech
PublicationThe article proposes an interpretation of the meaning of experience marketing as a tool in the process of sacralisation of products, and in a broader context – the so-called secular religion accompanying some contemporary big tech organizations. The article is of theoretical nature and the authors have intended to explain how big tech corporations, in line with the concept of experience marketing (digital platforms, in particular),...
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Design optimization of novel compact circular polarization antenna
PublicationThe paper describes a structure and a design optimization procedure of a miniaturized circular polarization antenna with elliptical ground plane slots and feed line with stepped-impedance stubs. Constrained optimization of all antenna parameters is executed in order to explicitly reduce the antenna size while maintaining required impedance axial ratio bandwidth of 5 GHz to 7 GHz at the same time. The size of the optimized antenna...
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Ancillary services to grids provided with distributed generation
PublicationThe paper introduces system for utilization of the customer-side generated energy. Additionally system can secure some ancillary services to grids. Those services include: current active filtering, load voltage stabilization and in case of grid voltage faults - uninterruptible load supplying (possible with energy storage device). Presented experimental results confirm flexibility of this arrangement in processes of power delivery...
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Trade differentiation and the characteristics of new imported and exported products - international panel data analysis
PublicationDrawing on o large panel of international economies we have shown how the set of imported and exported products evolves in economic growth process. Strong activity at the extensive margin, manifested through the rise in the number of active export and import lines, is typical for early stages of development. Trade diversification tendency, typical for a predominant mass of observations in our panel, is associated with changes in...
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Low-energy positron scattering from gas-phase uracil
PublicationQuantum scattering calculations are presented for the interaction of low energy positrons with the uracil molecule, an important component of biological systems. The rotational elastic and inelastic cross sections and vibrational inelastic cross sections are reported and compared with existing experiments, indicating a general trend of the cross sections different from the experimental findings and in line with what should be expected...
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DNA Methylation Changes Induced by Redox-Active Compounds—Choosing the Right PCR-Based Method
PublicationThe impact of catechins on the expression profile of redox-related genes in HT29 cell line has been studied recently by our group using Oxidative Stress RT2 Profiler PCR Array. Within the examined panel of 84 genes, the down-regulation of SRXN1 gene was unique among other up-regulated genes. We hypothesized that the observed down-regulation resulted from DNA methylation and have exploited this observation to choose the proper strategy...
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Protection of bridges against stray current corrosion
PublicationA case study of Siennicki Bridge stray current corrosion hazard is presented. A corrosion risk was caused by incorrectly designed tram line traction which goes over the bridge. No dielectric insulation between running rails and bridge steel construction was used. A variety of protection methods against stray currents are described. Characteristics of the endangered bridge were described. Impressed current cathodic protection system...
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A Trisection Filter Design With Negative Slope of Frequency-Dependent Crosscoupling Implemented in Substrate Integrated Waveguide (SIW)
PublicationThis letter reports on a novel realization of a microwave bandpass filter in a triplet configuration with a frequency-dependent crosscoupling implemented in substrate integrated waveguide (SIW). The design involves implementing dispersive coupling with a negative slope, a feature that allows the capabilities of the classic triplet topology to be extended. In this particular case, the implementation of two transmission zeros on...
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Noise emitted by SKM Trains in Gdansk
PublicationHigh intensity traffic of SKM trains in Gdansk carries a significant level of noise emission. SKM line runs through the central part of the city and therefore in the vicinity of residential areas and recreational facilities. This research was planned and performed to find out what was the real noise emission of SKM trains and to determine whether the measurement noise values are within allowed limits. Individual acoustic events...
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Elimination of impulsive disturbances from stereo audio recordings
PublicationThis paper presents a new approach to elimination of impulsive disturbances from stereo audio recordings. The proposed solution is based on vector autoregressive modeling of audio signals. On-line tracking of signal model parameters is performed using the stability-preserving Whittle-Wiggins-Robinson algorithm with exponential data weighting. Detection of noise pulses and model-based interpolation of the irrevocably distorted samples...