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Wyniki wyszukiwania dla: INTERNAL C SOURCE
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Copper binding by the cystatin C fragment. The role of histidine residues
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C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
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Cykl P-D-C-A w ciągłym doskonaleniu przedsiębiorstw
PublikacjaW niniejszym opracowaniu autor poddał analizie doskonalenie jakości z uwazględnieiem ciągłego poszukiwania i wdrażania form, metod, technik pozwalającyh przedsiębiorstwom udoskonalić poszczególne obszary funkcjonowania. Autor omówił poszczgólne składowe koncepcji PDCA oraz odniósł się do korzyści jakie mogą uzyskać przedsiębiorstwa doskonalące jakość w sposób ciągły.
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The rolling contact fatigue of WC/C-coated spur gears
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The Scuffing Resistance of WC/C Coated Spiral Bevel Gears
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublikacjaPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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BASECOL2023 scientific content
PublikacjaContext. The global context of making numerous data produced by researchers available requires collecting and organising the data, assigning meaningful metadata, and presenting the data in a meaningful and homogeneous way. The BASECOL database, which collects inelastic rate coefficients for application to the interstellar medium and to circumstellar and cometary atmospheres, meets those requirements. Aims. We aim to present the...
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Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
PublikacjaUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. A significant route of phase II drug metabolism is conjugation with glutathione (GSH), which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes. The aim of this work was to investigate the GSH-mediated metabolic pathway of a representative UA, C 2028. GSH supplemented incubations of C-2028 with rat, but not with human, liver...
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The impact of precipitation and external carbon source addition on biological nutrient removal in activated sludge systems – experimental investigation and mathematical modeling
PublikacjaThe aim of this study was to determine the effects of chemical precipitation and addition of external carbonsources on the denitrification capability and enhanced biological phosphorus removal (EBPR) interactions atthe ‘Wschod’ WWTP (600,000 PE) in Gdansk (northern Poland). For this purpose, different kinds of batch experimentswere carried out with the settled wastewater (without pretreatment and after coagulation-flocculation)and...
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Large‐Scale Traveling Ionospheric Disturbances Over the European Sector During the Geomagnetic Storm on March 23–24, 2023: Energy Deposition in the Source Regions and the Propagation Characteristics
PublikacjaMultiple Large-Scale Traveling Ionospheric Disturbances (LSTIDs) are observed in the European sector in both day-time and night-time during the magnetic storm on March 23–24, 2023. The Total Electron Content (TEC) observation from a network of GNSS receivers shows the propagation of LSTIDs with amplitudes between around 0.5 and 1 TECU originating from auroral and polar cusp regions down to southern Europe (35°N) with velocities...
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Dobre praktyki i narzędzia open source w zwinnym wytwarzaniu oprogramowania
PublikacjaZwinne wytwarzanie oprogramowania stało się bardzo popularne. Na podstawie projektu MOST Wiedzy przedstawiono procesy i narzędzia wspierające wytwarzanie oprogramowania na Politechnice Gdańskiej. Metodologia DDD (domain-driven design) wspierana przez repozytorium GIT oraz tzw. proces “cherry picking” powoduje, że proces wytwarzania oprogramowania jest elastyczny i efektywny. Dodatkowo wprowadzenie elementów CI (continuous integration),...
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Step-Up DC/DC Converters With Cascaded Quasi-Z-Source Network
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Coastal erosion as a source of mercury into the marine environment along the Polish Baltic shore
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Coastal erosion—a “new” land-based source of labile mercury to the marine environment
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Liquefaction of alder wood as the source of renewable and sustainable polyols for preparation of polyurethane resins
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Boron doped Nanocrystalline Diamond-Carbon Nanospike Hybrid Electron Emission Source
PublikacjaElectron emission signifies an important mechanism facilitating the enlargement of devices that have modernized large parts of science and technology. Today, the search for innovative electron emission devices for imaging, sensing, electronics, and high-energy physics continues. Integrating two materials with dissimilar electronic properties into a hybrid material is an extremely sought-after synergistic approach envisioning a...
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Plug-in to Eclipse environment for VHDL source code editor with advanced formatting of text
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Trans-Z-source-like inverter with built-in DC current blocking capacitors
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Callus of American ginseng (Panax quinquefolius) as a source of ginsenosides – medicinal secondary metabolites
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Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies
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Monetary Incentives Increase Metacognitive Confidence in Source Memory Performance in Patients With Schizophrenia
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Experimental investigations of commercial gas boiler as a heat source for the domestic micro-CHP
PublikacjaW pracy przedstawiono wyniki badań przeprowadzonych na prototypowym stanowisku mikrosiłowni domowej ORC z kotłem gazowym jako źródłem ciepła. Wykazano, iż jest możliwa adaptacja komercyjnego kotła gazowego dla potrzeb kogeneracji w skali mikro.
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Step-Up DC/DC Converters With Cascaded Quasi-Z-Source Network
PublikacjaW artykule zaprezentowano nowe rozwiązania dotyczące przekształtników energoelektronicznych DC-DC podwyższających napięcie z ogniw paliwowych. Istota rozwiązania zawiera się w zastosowaniu kaskadowo połączonych wejściowych obwodów pasywnych typu Quasi-Z, umozliwiających znaczne podwyższanie napięcia z wykorzystaniem stanu parcy zwarć gałęzi tranzystorowych przekształtnika.
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Open-transistor fault diagnostics in voltage-source inverters by analyzing the load current
PublikacjaPrzedstawiono nową metodę detekcji i lokalizacji uszkodzeń polegających na braku przewodzenia tranzystorów w falownikach napięcia zasilających silniki indukcyjne. Metoda jest rozszerzeniem, opracowanej wcześniej, metody wykorzystującej znormalizowane składowe stałe prądów obciążenia. Znormalizowane wartości średnie prądów powiązano z dodatkowymi wskaźnikami diagnostycznymi, które zawierają informacje o czasie trwania nieprzewodzenia...
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Human amniotic-fluid-derived stem cells: a unique source for regenerative medicine
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Vortex cavitation as a source of high level acoustic pressure generated by ship propellers
PublikacjaPraca przedstawia wyniki badań teoretycznych i eksperymentalnych nad mechanizmami fizycznymi generowania wysokiego ciśnienia akustycznego przez kawitujące wiry wierzchołkowe powstające na śrubach okrętowych
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Implementation of didactic simulation models in Open Source and SCORM compliant LMS systems.
PublikacjaModele symulacyjne są cenną pomocą w procesie dydaktycznym. Ich zastosowanie w systemach komputerowego wspomagania nauczania znacząco podnosi ich efektywność oraz pozwala na przeprowadzanie wirtualnych ćwiczeń laboratoryjnych (na przykład podczas nauczania na odległość). Niestety stosowane obecnie systemy LMS (Lerning Management System) nie są zadowalająco przystosowane do obsługi symulacyjnej zawartości dydaktycznej. W artykule...
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Open source solution LMS for supporting e-learning/blended learning engineers
PublikacjaW artykule zaprezentowano darmowe systemy zarządzania kształceniem na odległość wspomagające e-learningowe/mieszane nauczanie inżynierów. Pierwszy system TeleCAD został opracowany w ramach projektu Leonardo da Vinci (1998-2001). System TeleCAD był propozycją w projekcie V Ramowy CURE (2003-2006). W roku 2003 dzięki projektowi Leonardo da Vinci EMDEL (2001-2005) Centrum Edukacji Niestacjonarnej Politechniki Gdańskiej wybrało system...
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The PWM current source inverter with IGBT transistors and multiscalar model control system
PublikacjaW niniejszym artykule przedstawiono struktury układów sterowania maszyny indukcyjnej zasilanej z falownika prądu. Przedstawiono metodę modulacji szerokości impulsów dla falownika prądu. Pokazano modele matematyczne maszyny indukcyjnej klatkowej zasilanej z falownika prądu. Przedstawiono trzy układy regulacji sterowania multiskalarnego z czego dwa są nowe. Rozważania teoretyczne zweryfikowano za pomocą badań symulacyjnych.
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Photovoltaic solar cells and modules as the source of electricity in the world and its future in Poland
PublikacjaJedną z metod ograniczenia emisji CO2 na świecie i w Polsce jest zastępowanie paliw kopalnych odnawialnymi źródłami energii. Systemy fotowoltaiczne, generujące energie elektryczną, są uważane za technologię wpisująca się w politykę zrównoważonego rozwoju dzięki znacznemu postępowi technologicznemu w zakresie ich wytwarzania i znacznej redukcji kosztów tych systemów.W artykule naświetlono postęp, jaki dokonał się w tej dziedzinie...
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Electrolytic deposition of reactive element thin films on Crofer 22 APU and evaluation of the resulting high-temperature corrosion protection properties at 700 °C–900 °C
PublikacjaThis article presents electrolytic deposition of thin Rare Earth (RE) coatings on Crofer 22 APU stainless steel substrates for high temperature applications, such as interconnects in solid oxide cell stacks. The deposition of coatings based on yttrium-, gadolinium-, lanthanum-, and cerium nitrates is discussed. The high temperature corrosion properties of surface-modified steels were examined using thermogravimetry and electrical...
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On the Role of Polarimetric Decomposition and Speckle Filtering Methods for C-Band SAR Wetland Classification Purposes
PublikacjaPrevious wetlands studies have thoroughly verified the usefulness of data from synthetic aperture radar (SAR) sensors in various acquisition modes. However, the effect of the processing parameters in wetland classification remains poorly explored. In this study, we investigated the influence of speckle filters and decomposition methods with different combinations of filter and decomposition windows sizes on classification accuracy....
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PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells
PublikacjaTwo cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability.Approximately 5-10% of breast and ovarian cancers result from inherited alterations or mutations in these genes.Remarkably, BRCA1/BRCA2-deficient cells are hypersensitive to selective inhibition of poly(ADPribose) polymerase 1 (PARP-1),...
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The effect of lyophilization on selected biologically active components (vitamin c, catalase, lysozyme), total antioxidant capacity and lipid oxidation in human milk
PublikacjaHuman milk is rich in polyunsaturated fatty acids, as well as lysozyme, vitamin C and other bioactive compounds. The effect of lyophilization on the content of antioxidants (vitamin C and catalase CAT), bactericidal compounds (lysozyme), total antioxidant capacity (TAC) and lipid peroxidation in human milk was investigated in this study. Samples of mature human milk were collected from five healthy women who gave birth on the scheduled...
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The fate and contamination of trace metals in soils exposed to a railroad used by Diesel Multiple Units: Assessment of the railroad contribution with multi-tool source tracking
PublikacjaSoil samples from cut slopes from lightly loaded railway lines used by Diesel Multiple Units for 5 years in Gdansk (Poland) were collected and analyzed for trace metals (TMs): Zn, Pb, Cd, Ni, Cr, Cu, and Fe. The main aim was to assess soil enrichment, contamination status, and distribution of TMs relative to the distance from the railway track. Extensive source tracking analyses were performed using cluster analysis (CA) and the...
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Estimation and modeling hydrolysis of slowly biodegradable substrate based on the batch respirometric tests in activated sludge systems
PublikacjaNowadays, appropriate determination of chemical oxygen demand (COD) fractionation together with degradation kinetics of organic compounds have a prime importance on the design and operation of activated sludge systems. Batch respirometric tests based on the oxygen uptake rates (OUR) and corresponding COD is accepted method to reflect the consumption of biodegradable substrates. The influence of the readily biodegradable (Ss) fraction...
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The Simulation of Activated Sludge System for Optimization of Predictive Aeration at Large WWTP
PublikacjaEffective use of biodegradable substrates as an internal carbon sources (ICS) for denitrification and EBPR and predicting performance of aeration systems during nitrification in activated sludge bioreactors, may be useful in realization the sustainable development by potentially saving energy consumption at WWTPs. A large number of WWTPs use activated sludge systems with an integrated removal of carbon, nitrogen and phosphorus...
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An integrated geotechnical and geophysical investigation of landslide in Chira town, Ethiopia
PublikacjaLandslides pose a significant threat to infrastructure, property, and human lives in many regions worldwide, including Chira town in Ethiopia. This study presents an integrated geotechnical and geophysical investigation aimed at identifying the contributing factors to landslides in Chira town, Ethiopia, with a focus on a recent landslide event. The methodology employed a combination of geotechnical and geophysical techniques to...
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Employee Commitment Matters for CSR Practice, Reputation and Corporate Brand Performance—European Model
PublikacjaSo far, there have been no studies that explore how employee brand commitment moderates CSR practice outcomes. Employee brand commitment is often claimed as a focal input and output of the CSR. So, it means that it shapes CSR conditions. Then, it is a moderator. This study aims to verify it. Besides, commitment exists in many forms and can be achieved in many ways. Hence the question, if employees are committed to the brand, then...
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Determination of free tyrosine in equestrian supplements by LC–MS/MS and comparison of its quantity with total free amino acids content in view of doping control
PublikacjaThe reports on the probable beneficial impact of tyrosine (TYR) supplementation on performance enhancement have contributed to the growth of interest in TYR in equestrian sports field and related industries, such as the manufacture of dietary and nutritional supplements. In this study, the first attempt to the assessment of horses exposure to TYR during nutritional supplementation was demonstrated by quantification of unbound TYR...
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Effects of FSW Tool Plunge Depth on Properties of an Al-Mg-Si Alloy T-Joint: Thermomechanical Modeling and Experimental Evaluation
PublikacjaOne of the main challenging issues in friction stir welding (FSW) of stiffened structures is maximizing skin and flange mixing. Among the various parameters in FSW that can affect the quality of mixing between skin and flange is tool plunge depth (TPD). In this research, the effects of TPD during FSW of an Al-Mg-Si alloy T-joint are investigated. The computational fluid dynamics (CFD) method can help understand TPD effects on FSW...
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Comparison of Renewable Energy Sources in ‘New’ EU Member States in the Context of National Energy Transformations
PublikacjaThe European Union strives to create sustainable, low-carbon economies; therefore, energy policies of all member states should move towards renewable energy sources (RES). That concerns also the so-called new EU member states. These countries, on the one hand, are characterized by significant historical similarities in terms of post-communist legacy and adopted development strategies linked with the EU membership, and on the other...
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Nonconventional 1,8-Diazafluoren-9-One Aggregates for Green Light Enhancement in Hybrid Biocompatible Media
PublikacjaOrganic aggregates currently play a prominent role, mainly for their unique optoelectronic properties in the aggregated state. Such properties can be related to the aggregates’ structure and the molecular packing mode. In the literature, we have well-established models of H and J aggregates defined based on the molecular exciton model. However, unconventional aggregates, the most unrecognized forms, have been generating interest...
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Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) is responsible for the hydrolysis of biologically inactive sulfated steroids into their active un-sulfated forms and promotes the growth of various hormone-dependent cancers (e.g., breast cancer). Therefore, the STS enzyme is a promising therapeutic target for the treatment of steroid-sensitive cancers. Herein, we report the synthesis and biological evaluation of sulfamate analogs as potential STS inhibitors...
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Phospholipid-functionalized gold electrode for cellular membrane interface studies - interactions between DMPC bilayer and human cystatin C
PublikacjaThis work describes the electrochemical studies on the interactions between V57G mutant of human cystatin C (hCC V57G) and membrane bilayer immobilized on the surface of a gold electrode. The electrode was modified with 6-mercaptohexan-1-ol (MCH) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). DMPC was used as a membrane mimetic for monitoring electrochemical changes resulting from the interactions between the functionalized...
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Cascade Object Detection and Remote Sensing Object Detection Method Based on Trainable Activation Function
PublikacjaObject detection is an important process in surveillance system to locate objects and it is considered as major application in computer vision. The Convolution Neural Network (CNN) based models have been developed by many researchers for object detection to achieve higher performance. However, existing models have some limitations such as overfitting problem and lower efficiency in small object detection. Object detection in remote...
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Modeling the Effect of External Carbon Source Addition under Different Electron Acceptor Conditions in Biological Nutrient Removal Activated Sludge Systems
Publikacjahe aim of this study was to expand the International Water Association Activated Sludge Model No. 2d (ASM2d) to predict the aerobic/anoxic behavior of polyphosphate accumulating organisms (PAOs) and “ordinary” heterotrophs in the presence of different external carbon sources and electron acceptors. The following new aspects were considered: (1) a new type of the readily biodegradable substrate, not available for the anaerobic activity...
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Design of a test bench for determining the general characteristics of an internal combustion engine using a hydraulic power take-off system
PublikacjaThe paper presents a design of an engine test bench, which is used to determine the general characteristics of a truck engine using a power take-off (PTO). PTO drives a hydraulic system that generates a load on the engine at various points in its operation in the power range specified by the hydraulic system. The design allows for stationary and mobile tests with the test bench mounted on the truck, without any modification of...
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The type of blood used to feed Aedes aegypti females affects their cuticular and internal free fatty acid (FFA) profiles
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MODELLING OF CONCRETE FRACTURE AT AGGREGATE LEVEL USING DEM BASED ON X-RAY mu CT IMAGES OF INTERNAL STRUCTURE
PublikacjaThe paper describes two-dimensional meso-scale numerical results of fracture in notched concrete beams under quasi-static three-point bending. Concrete was modelled as a random heterogeneous 4-phase material composed of aggregate particles, cement matrix, interfacial transitional zones (ITZs) and air voids. As a numerical approach, the discrete element method (DEM) was used. The concrete micro-structure in calculations was directly...