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Wyniki wyszukiwania dla: HUMAN AORTIC BIOPROSTHESIS
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Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract
PublikacjaThe present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...
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Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2
PublikacjaWe combine molecular dynamics, statistical mechanics, and hybrid quantum mechanics/molecular mechanics simulations to describe mechanistically the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp). Our study analyzes the binding mode of both natural triphosphate substrates as well as remdesivir triphosphate (the active form of drug), which is bound preferentially over ATP by RdRp while...
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The impact of interactions between polyphenolic antioxidants on the redox-related chemical and biological properties of their mixtures – the extension of food synergy concept.
PublikacjaThe results of studies indicate that chemopreventive efficiency of isolated phytochemicals is lower than that of polyphenol-rich foods. This discrepancy has been ascribed to the food synergy concept that assumes additive or even synergistic influence of different food ingredients on human health. The results presented in the dissertation made it possible to propose an alternative and innovative explanation of these observations. The...
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Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage
PublikacjaExposure to high levels of different environmental pollutants is known to be associated with induction of DNA damage in humans. Thus DNA repair is of great importance in preventing mutations and contributes crucially to the prevention of cancer. In our study we have focused on quantitative analysis of Gentiana asclepiadea aqueous or methanolic extracts obtained from flower and haulm, their antioxidant potency in ABTS post-column...
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The Quality of the Outflow from Conventional WWTPs and Treatment Wetlands
PublikacjaUntil recently the humic substances were considered to have no negative impact on human health. Therefore elimination of these substances from potable water was only performed due to aesthetic reasons. In the recent years, however, it was found out that humic substances may cause unacceptable smell of water or cumulate toxic substances by complexing metal ions and adsorption of persistent organic pollutants such as pesticides,...
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Koncepcja i analiza sensora/aktuatora piezoelektrycznego do pomiaru procesu starzenia się ludzkiej skóry
PublikacjaNiniejszy artykuł przedstawia nową koncepcję piezoelektrycznego sensora/aktuatora przeznaczonego do pomiaru właściwości mechanicznych tkanek miękkich a w szczególności skóry ludzkiej. Wyjaśnione jest analityczne podejście z wykorzystaniem schematu zastępczego Mason’a określającego aktuator w stanie rezonansu oraz opis metody impedancji elektromechanicznej wykorzystanej w systemie pomiarowym. Analiza z użyciem metody elementów...
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Knowledge engineer – more than only technical position. The concept of knowledge engineering education at the Faculty of Management and Economics
PublikacjaOrganizational learning means an effective knowledge management. Management is nothing more than the constant decision-making. Therefore organizational learning must be seen through the prism of decisions taken at all levels. Unfortunately decisions are never taken within comfortable conditions. Decision maker suffers from a lack of any support. There is often a problem with human resources having right skills, sometimes they do...
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The essence of marine and coastal space – an interdisciplinary perspective
PublikacjaSea space has been undergoing a profound transformation. Although it retains its inspirational function in arts, literature and philosophy, it has been gaining new anthropogenic dimensions in eco-nomics and urban planning as a source of satisfying human needs i.e. the provision of harmony, beauty, off-shore energy, and biotech substances. Therefore, in this paper marine space is analyzed from a mul-tidimensional perspective of...
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Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70
PublikacjaThe J-domain protein Zuotin is a multi-domain eukaryotic Hsp70 co-chaperone. Though it is primarily ribosome-associated, positioned at the exit of the 60S subunit tunnel where it promotes folding of nascent polypeptide chains, Zuotin also has off-ribosome functions. Domains of Zuotin needed for 60S association and interaction with Hsp70 are conserved in eukaryotes. However, whether the 4-helix bundle (4HB) domain is conserved remains...
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Filozofować z głębi człowieczeństwa. O fenomenologii Andrzeja Półtawskiego.
PublikacjaDokonując krytyki tradycji nowożytnego empiryzmu i kartezjańskiego dualizmu Półtawski tworzy realistyczną i dynamiczną interpretację bytu ludzkiego. Przeżywanie, odczuwanie zmysłowe nie jest poślednią odmianą poznania jak i operacją dostarczania jedynie elementów, budulca poznaniu, ale odrębnym sposobem bycia w świecie, jest symbiotycznym kontaktem z otoczeniem, formą życia. Zrywa on radykalnie z tradycją brentanowsko-husserlowską...
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HPLC-coupled post-column derivatization aims at characterization and monitoring of plant phytocomplexes, not at assessing their biological properties
PublikacjaTwo recent decades of research identified a number of environmental factors as well as mechanisms leading to pathogenic processes in the human organism. A common factor in pathogenesis of many diseases is oxidative stress, a condition in which the production of damaging reactive oxygen species (ROS), present in the body as an inevitable consequence of respiration and exacerbated by the inflammatory response and by exogenous factors...
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In search of a common ground for the space sciences
PublikacjaThe paper discusses the relations between various aspects of human activities performed in space, taking into consideration the past, present and future contexts. Interdisciplinarity and integrity of technological issues combined with legal and management issues were emphasized. Consequently, it was recognized that it is necessary to build a network of universities, research-and-development companies and engineering companies....
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Biometryczna kontrola dostępu
PublikacjaOpisano szczegółowo algorytm detekcji oraz identyfikacji człowieka na podstawie punktów nodalnych twarzy. Zdefiniowano pojęcia: biometria, proces pomiaru biometrycznego, metody biometrycznej identyfikacji oraz kontrola dostępu. Przedstawiono opis opracowanego systemu biometrycznej identyfikacji wykorzystującego sztuczne sieci neuronowe. Podano wyniki badań oraz przeprowadzono ich wnikliwą dyskusję.Biometrics is the study of automated...
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Company Culture, Knowledge Sharing and Organizational Performance. The Employee’s Perspective
PublikacjaKnowledge sharing, as a basic prerequisite for knowledge creation, is a dynamic social process characterized by profound human interactions. The process of knowledge sharing can be supported by organizational culture which is a set of values and norms giving identity to each enterprise. As a valuable element of intellectual capital, organizational culture contributes to achieving strategic business goals. The purpose of this article...
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Specific detection of Alternaria alternata by PCR and real-time PCR
PublikacjaFungi of Alternaria genus are cosmopolitan organisms, which spores can be found in the air, soil, water, clothing and food. They commonly occur as saprotrophs on the plant remains, contributing to the decomposition of organic matter. Additionally, they are components of the normal human and animal skin flora. Alternaria spp. are also known human allergens, causing hay fever and allergic reactions that can lead to the development...
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Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells
PublikacjaThe specific role of size scale, surface capping, and aspect ratio of zinc oxide (ZnO) particles on toxicity toward prokaryotic and eukaryotic cells was investigated. ZnO nano and microparticles of controlled size and mor- phology were synthesized by wet chemical methods. Cytotoxicity toward mammalian cells was studied using a human osteoblast cancer cell line and antibacterial activity using Gram-negative bacteria (Escherichia...
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IoT for healthcare applications
PublikacjaThis chapter summarizes IRACON contributions related to the application of IoT in healthcare. It consists of the following three sections. Section 8.1 presents the measurement campaigns and the related statistical analysis to obtain various channel models for wearable and implantable devices. In addition, the importance of physical human-body phantoms used for channel, Specific Absorption Rate (SAR), and Electromagnetic (EM) exposure...
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Assessment of the Environmental Impact of a Car Tire throughout Its Lifecycle Using the LCA Method
PublikacjaThere are numerous threats to the natural environment that pose a significant risk both to the environment and to human health, including car tires. Thus, there is a need to determine the impact of the life cycle of car tires on the environment, starting with the processes of raw materials acquisition, production, and ending with end-of-life management. Therefore, the authors of this study chose to do research on passenger car...
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THE EFFECT OF LOG SORTING STRATEGY ON THE FORECASTED LUMBER VALUE AFTER SAWING PINE WOOD
PublikacjaThe optimal transformation path for the resource is determined by the quality of a log combined with its dimension. The commercial value of derived products is also closely connected with the size and extent of containing wood deficiencies. The results of studies with three diverse strategies for log sorting are presented in the paper. Resource assessment by a worker without extensive experience in sorting logs, the certified grading...
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Cognitive motivations and foundations for building intelligent decision-making systems
PublikacjaConcepts based on psychology fit well with current research trends related to robotics and artificial intelligence. Biology-inspired cognitive architectures are extremely useful in building agents and robots, and this is one of the most important challenges of modern science. Therefore, the widely viewed and far-reaching goal of systems research and engineering is virtual agents and autonomous robots that mimic human behavior in...
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Work–life balance: Does age matter?
PublikacjaWork-life balance is a priority of EU policies but at the same time demographic change affects the labour market. Employers have to deal with the ageing of their employees and adjust human resource management to maintain their competitiveness. The purpose of the article is to answer research questions: whether the age of workers determines their assessment of the work-life balance, and whether there is a relationship between the...
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Low-cost Adsorbents Derived from Agricultural By-products/Wastes for Enhancing Contaminant Uptakes from Wastewater: A Review
PublikacjaA major threat to the comfort of human life has been imposed by increased industrialization and urbanization. The generation and disposal of huge amounts of toxic materials and pollutants have heavily contaminated our environment. Some Organics such as synthetic dyes (SD) and heavy metals (HM) are becoming increasingly prevalent as the most dangerous pollutants in soil and surface water environments. They are...
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Proposal of a System Loss Model for Body Area Network in Passenger Ferry Environment
PublikacjaIn the paper, proposal of an empirical off-body system loss model for Body Area Networks working in a passenger ferry environment at 2.45 GHz has been presented. The measurements were carried out for dynamic scenarios in the discotheque passenger ferry environment. The general model formula consists of three components: mean system loss, attenuation resulting from the variable antenna position on the human body, and attenuation...
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FEEDB: A multimodal database of facial expressions and emotions
PublikacjaIn this paper a first version of a multimodal FEEDB database of facial expressions and emotions is presented. The database contains labeled RGB-D recordings of people expressing a specific set of expressions that have been recorded using Microsoft Kinect sensor. Such a database can be used for classifier training and testing in face recognition as well as in recognition of facial expressions and human emotions. Also initial experiences...
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Dynamics of a simplified HPT model in relation to 24h TSH profiles
PublikacjaWe propose a simplified mathematical model of the hypothalamus-pituitary-thyroid (HPT) axis in an endocrine system. The considered model is a modification of the model proposed by Mukhopadhyay and Bhattacharyya in [10]. Our system of delay differential equations reconstructs the HPT axis in relation to 24h profiles of human in physiological conditions. Homeostatic control of the thyroid-pituitary axis is considered by using...
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Mashup Approaches for Improving Service Oriented Business Scenarios
PublikacjaTwo kinds of business scenarios are considered: application- and service-oriented. It is shown that the former are more flexible and easier reconfigurable for both traditional (human-oriented) and IT services. Moreover, complex IT services can be created by simple IT services using the modern mashup technology. It is the reason why such business scenarios can be modeled by BPMN in much easier ways. A simple example of a supply...
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Measuring the immeasurable: system usability, user satisfaction, and quality management.
PublikacjaZmierzyć niemierzalne: funkcjonalność systemu, satysfakcja użytkownika a zarządzanie jakością.W artykule przedyskutowano możliwości opracowania nowego podejścia badawczego łączącego badania funkcjonalności, badania konsumenckie oraz wybrane techniki zarządzania jakością. Perspektywa badań konsumenckich jest postrzegana jako szczególnie obiecująca w kontekście rozwijającego się rynku produktów interaktywnych oraz dalszego rozwoju...
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Behaviour of orthotropic surgical implant in hernia repair due to the material orientation and abdomen surface deformation
Publikacjarelation to the different range of typical deformations observed in different directions and zones of abdomen surface due to the patients’ life activities, has a significant influence on the extreme junction forces in the mesh–tissue connections and hence the repair persistence. The finite element model of the orthotropic implant was developed, and the junction forces in the connections of tissue and mesh were studied. The kinematical...
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Investigating the sustainability, utilisation, consumption and conservation of sea mammals – A systematic review
PublikacjaAlmost 80 % of the oceans, especially the Arctic and Subarctic are primarily inhabited by marine mammals. Marine species depend mostly on sea ice for food, raising their young ones and safeguarding themselves from predators. Consumption of marine mammals has always been recommended as healthy, but the truth is that it can be detrimental for human health because of sea water pollution from trash and chemicals. This systematic review...
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Detection of propofol concentrations in blood by Raman spectroscopy
PublikacjaIn this paper we present a proof-of-concept of a Raman spectroscopy-based approach for measuring the content of propofol, a common anesthesia drug, in whole human blood, and plasma, which is intended for use during clinical procedures. This method utilizes the Raman spectroscopy as a chemically–sensitive method for qualitative detection of the presence of a drug and a quantitative determination of its concentration. A number of...
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Synthesis, Molecular Structure, Metabolic Stability and QSAR Studies of a Novel Series of Anticancer N-Acylbenzenesulfonamides
PublikacjaA series of novel N-acyl-4-chloro-5-methyl-2-(R1-methylthio)benzenesulfonamides 18–47 have been synthesized by the reaction of N-[4-chloro-5-methyl-2-(R1-methylthio) benzenesulfonyl]cyanamide potassium salts with appropriate carboxylic acids. Some of them showed anticancer activity toward the human cancer cell lines MCF-7, HCT-116 and HeLa, with the growth percentages (GPs) in the range from 7% to 46%. Quantitative structure-activity relationship...
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Quiet Quitting and its Link With Knowledge Risks in Organizations – Theoretical Insights
PublikacjaPurpose: Quiet quitting has become a widely publicized concept, driven by social media in the United States and other countries in 2022. It is a term used to describe the phenomenon by which employees do the least amount of their work, just enough to meet the requirements of one’s job description (Mahand and Caldwell, 2023). The trend is spreading quickly among young workers. It can potentially harm individuals, job performance,...
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The computational methods in the development of a novel multianalyte calibration technique for potentiometric integrated sensors systems
PublikacjaIn recent years, integration and miniaturization of ion-selective electrodes (ISEs) have brought many benefits resulting in the possibility of simultaneous determination of the ions concentration in small volume samples. One of the key problems related to the preparation of potentiometric integrated sensors systems (PISSs) is a calibration procedure due to the necessity to calibrate each particular sensor separately. The main aim...
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Exhaled breath analysis by resistive gas sensors
PublikacjaBreath analysis has attracted human beings for centuries. It was one of the simplest methods to detect various diseases by using human smell sense only. Advances in technology enable to use more reliable and standardized methods, based on different gas sensing systems. Breath analysis requires the detection of volatile organic compounds (VOCs) of the concentrations below individual ppm (parts per million). Therefore, advanced detection...
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Adopting Collaborative Games into Agile Requirements Engineering
PublikacjaIn agile software development, where great emphasis is put on effective informal communication involving diverse stakeholders, success depends on human and social factors. Not surprisingly, the Agile Manifesto advocates principles and values such as “individuals and interactions over processes and tools”, “focus on the customer”, “collaborate regularly”, “communicate face-to-face within the team” and “have regular team introspection”....
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In vivo performance of intraperitoneal onlay mesh after ventral hernia repair
PublikacjaBackground: Ventral hernia repair needs to be improved since recurrence, postoperative pain and other complications are still reported in many patients. The behavior of implants in vivo is not sufficiently understood to design a surgical mesh mechanically compatible with the human abdominal wall. Methods: This analysis was based on radiological pictures of patients who underwent laparoscopic ventral hernia repair. The pictures...
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Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
PublikacjaWith the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19, discovering new antifungals is extremely important. Natural and synthetic xanthones are promising derivatives, although only few reports have demonstrated their antifungal mechanism of action in detail. Newly synthetized by us xanthone derivative 44 exhibited strong antifungal...
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Social entrepreneurship and its hybridity determining resource challenges and chances
PublikacjaIn this conceptual paper, the author aims to grasp what are the particular challenges and opportunities in social entrepreneurship, in terms of resource access and mobilization, considering the hybrid nature of social enterprise. To this end, the author points to the nature of hybridity and discusses what advantages and disadvantages are inherent in financial, human and physical resources access for social enterprises as hybrid...
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A body position influence on ECG derived respiration
PublikacjaAn influence of a human body position on ECG derived respiration (EDR) signal is presented in the paper. Examinations were performed during deep, suspended and normal breathing for eight people in four different body positions. EDR and thoracic impedance signals were compared using correlation and standard deviation coefficients. Obtained results have shown that it is possible to monitor breath activity of people being in different...
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Prebiotics and probiotics in food
PublikacjaNowadays, food is not only used to satisfy hunger and is a source of nutrients, but is also considered a factor that directly affects human health. Consumers are looking for high-quality products that contain bioactive ingredients that affect the proper functioning of the body and good mood. Functional foods, which must exhibit health benefits when consumed as part of a balanced diet, are becoming increasingly popular among health-conscious...
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The concept of anti-collision system of autonomous surface vehicle
PublikacjaThe use of unmanned vehicles in various fields of science and the economy is becoming more common. An extremely important aspect of creating this type of solution is to provide autonomous vehicle navigation, which does not require interference of the human factor or in which it is limited to a minimum. This article discusses the concept of autonomous anti-collision system of unmanned surface vehicle. It proposed a sensor system...
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Klasyfikacja wyrobów tytoniowych z wykorzystaniem elektronicznych nosów
PublikacjaZapobieganie nielegalnej dystrybucji wyrobów tytoniowych w Polsce stanowi poważny problem. Wyroby tytoniowe przemycane do Polski mogą charakteryzować się niższą jakością, wynikającą z wykorzystania surowców gorszego gatunku. Jednym z rozwiązań zmniejszających skalę tego problemu mogą być działania ograniczające przemyt przez granice państwa. Autorzy pracy uważają, że wykorzystanie elektronicznych nosów do rutynowych kontroli przewożonych...
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Identification of pollutants at the adjacent areas to the landfill site using two dimensional gas chromatography with mass spectrometry technique
PublikacjaMunicipal landfills are considered one of the main sources of air pollutants. In this article is presented the use of a modern analytical technique: a two dimensional gas chromatography to identify the substances in the atmospheric air near a waste processing plant located in Gdansk. In order to determine the types of substances occurring in different atmospheric conditions, the study was conducted from February to April 2016....
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A navigation device utilizing body communication channel for mobile wearable systems
PublikacjaA novel touch sensor utilizing a body communication technology is presented in the paper. The proposed device accepts orders (gestures) only from a person wearing it. Moreover, when comparing it to a similar, however an optical one, it appears as a less power consumable. Preliminary results of its properties examination are presented and discussed. Additionally, the developed sensor allows to measure a human body the electrical...
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Improving web user experience with caching user interface
PublikacjaOften, Web technologies are used to operate or to configure network-enabled equipment, to configure and administer modular applications, or as teaching environments. The comfort of human work requires a similar response time in these applications as in the Internet. To improve response time, various forms of caching at different levels are employed. To improve the user experience in regard to response time when performing specific...
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Small rov to detection and identification of dangerous underwater objects
PublikacjaA small unmanned underwater vehicle (UUV) to inspection of an undersea space is presented in the paper. Its behavior is controlled by a trained pilot. Correct detection and identification of targets depends on vehicle'sprecise displacement along a predefined route. Nowadays, the UUVs are equipped with an automatic control system to execute some basic maneuvers without constant human interventions. Hence, in the paper, an autopilot...
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Load function walking pedestrian on the footbridge.
PublikacjaModern foot bridges are more and more sensitive to variable load created by moving pedestrians. These are several reasons for that. Quickly growing up road infrastructure forces us to build foot bridges just to reconnect one piece of land, separated now by the new road or railway. These bridges are lightweight because the only live load acting on them comes from pedestrians.The paper focuses on the definition of human induces dynamic...
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Climate change impact on groundwater resources in sandbar aquifers in southern Baltic coast
PublikacjaShallow coastal aquifers are vulnerable hydrosystems controlled by many factors, related to climate, seawater‑freshwater interactions and human activity. Given on‑going climate change, sea level rise and increasing human impact, it is especially true for groundwater resources situated in sandbars. We developed numerical models of unsaturated zone water flow for two sandbars in northern Poland: the Vistula Spit and the Hel Spit...
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Visual content representation and retrieval for Cognitive Cyber Physical Systems
PublikacjaCognitive Cyber Physical Systems have gained significant attention from academia and industry during the past few decade. One of the main reasons behind this interest is the potential of such technologies to revolutionize human life since they intend to work robustly under complex visual scenes, which environmental conditions may vary, adapting to a comprehensive range of unforeseen changes, and exhibiting prospective behavior...
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Toxoplasma gondii Recombinant antigen AMA1: Diagnostic Utility of Protein Fragments for the Detection of IgG and IgM Antibodies
PublikacjaToxoplasma gondii is an important zoonotic protozoan that infects a wide variety of vertebrates as intermediate hosts. For this reason, the diagnosis of this disease is very important and requires continuous improvement. One possibility is to use recombinant antigens in serological tests. Apical membrane antigen 1 (AMA1), a protein located in specific secretory organelles (micronemes) of T. gondii, is very interesting in regard...