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Alphitobius diaperinus larvae (lesser mealworm) as human food – An approval of the European Commission – A critical review
PublikacjaDue to the increasing threat of climate change and the need for sustainable food sources, human consumption of edible insects or entomophagy has gained considerable attention globally. The larvae of Alphitobius diaperinus Panzer (Coleoptera: Tenebrionidae), also known as the lesser mealworm, have been identified as a promising candidate for mass-rearing as a food source based the on evaluation on several aspects such as the production...
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Hierarchical influence diagrams for incorporating human and organizational factors in risk assessment of hazardous industrial systems
PublikacjaArtykuł dotyczy podstawowych zagadnień związanych z czynnikami organizacyjnymi i ludzkim w analizie ryzyka złożonych systemów przemysłowych. Analizuje się podobieństwa i różnice pomiędzy hierarchicznymi diagramami wpływu i hierarchicznym procesem analizy decyzyjnej i na tej podstawie proponuje się uogólnione podejście do rozważanej analizy decyzyjnej uwzględniające dane rozmyte.
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ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators
PublikacjaFluoryzujące analogi fosfolipidów NBD-PE, NBD-PC i NBD-PS zostały wykorzystane w celu wykazania, że białko Cdr1p i jego inne homologi, Cdr2p i Cdr3p, należące do grupy białek zawierających tzw. kasetę wiążącą ATP (ABC), zachowują się jak ogólne przenośniki lipidów. Wyniki badań pokazują, że transportery typu ABC występujące w C. albicans są przenośnikami fosfolipidów i aktywność ta może być jedna z fizjologicznych funkcji białek.
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Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems
PublikacjaSince human-associated bacteria have been recognized as vectors in two - way gene transmission between the pathogenic and environmental populations, health hazard connected with wastewater discharge requires reevaluation. In this paper the particular attention was given to antimicrobial-resistance of Escherichia coli and enterococci isolated from wastewater and wastewater impacted environments. The obtained results showed that...
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Mechanical response of human thoracic spine ligaments under quasi-static loading: An experimental study
PublikacjaPurpose This study aimed to investigate the geometrical and mechanical properties of human thoracic spine ligaments subjected to uniaxial quasi-static tensile test. Methods Four human thoracic spines, obtained through a body donation program, were utilized for the study. The anterior longitudinal ligament (ALL), posterior longitudinal ligament (PLL), capsular ligament (CL), ligamenta flava (LF), and the interspinous ligament and...
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INTRODUCING GREENERY INTO A BUILDING BASED ON ITS IMPACT ON HUMAN WELLBEING - REVIEW OF THEORIES AND METHODS IN ARCHITECTURE
PublikacjaGreenery around and within buildings is an integral part of architectural space. Although science is providing more and more knowledge about the impact of greenery on human well-being, there is still a lack of guidelines on how to apply this knowledge in architectural design. The purpose of this review article is to prepare the ground for further research on how to support architectural design in integrating greenery as a co-creative...
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Podstawowe sposoby zwiększania wiarygodności wykonania przebiegów wymagających udziału człowieka w human workflow
PublikacjaOpisano pojęcie procesu biznesowego oraz przepływu pracy w kontekście automatyzacji mającej na celu optymalizację działań i podniesienie jakości usługi. Przedstawiono charakterystykę procesów pracy angażujących człowieka oraz wykorzystujących dedykowane wzorce przepływów tego typu. Zaproponowano zwiększenie stopnia automatyzacji wykonania procesu wraz z metodami zwiększania wiarygodności wykonania przebiegów pracy przez kontrolę...
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Validation of Hydraulic Mechanism during Blowout Trauma of Human Orbit Depending on the Method of Load Application
PublikacjaThe more we know about mechanisms of the human orbital blowout type of trauma, the better we will be able to prevent them in the future. As long as the buckling mechanism’s veracity is not in doubt, the hydraulic mechanism is not based on equally strong premises. To investigate the correctness of the hydraulic mechanism’s theory, two different methods of implementation of the hydraulic load to the finite element method (FEM) model...
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Nonlinear dynamic analysis of the pure “buckling” mechanism during blow-out trauma of the human orbit
PublikacjaConsidering the interplay between orbital bones and intraorbital soft tissues, commonly accepted patterns of the blow-out type of trauma within the human orbit require more thorough investigation to assess the minimal health-threatening impact value. Two different three-dimensional finite element method (FEM) models of the human orbital region were developed to simulate the pure “buckling” mechanism of orbital wall fracture in...
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Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance
PublikacjaIdentification of active electrodes that record task-relevant neurophysiological activity is needed for clinical and industrial applications as well as for investigating brain functions. We developed an unsupervised, fully automated approach to classify active electrodes showing event-related intracranial EEG (iEEG) responses from 115 patients performing a free recall verbal memory task. Our approach employed new interpretable...
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Multifactor consciousness level assessment of participants with acquired brain injuries employing human–computer interfaces
PublikacjaBackground A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the...
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Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
PublikacjaObjective: Our goal was to analyze the electrophysiological response to direct electrical stimulation (DES) systematically applied at a wide range of parameters and anatomical sites, with particular focus on neural activities associated with memory and cognition. Methods: We used a large set of intracranial EEG (iEEG) recordings with DES from 45 subjects with electrodes...
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A novel in vivo approach to assess strains of the human abdominal wall under known intraabdominal pressure
PublikacjaThe study concerns mechanical behaviour of a living human abdominal wall. A better mechanical understanding of a human abdominal wall and recognition of its material properties is required to find mechanically compatible surgical meshes to significantly improve the treatment of ventral hernias. A non-invasive methodology, based on in vivo optical measurements is proposed to determine strains of abdominal wall corresponding to...
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The dispersive micro-solid phase extraction method for MS-based lipidomics of human breast milk*
PublikacjaA simple and rapid microextraction method ensuring high lipidome coverage was developed for liquid chromatography mass spectrometry (LC-MS)-based lipidomics of human breast milk. The dispersive microsolid phase extraction (D-µ-SPE) technique, coupled with the design of experiment (DoE) method, enabled the study of the influence of several conditions (desorption solvent, stationary phase ratio, and sorption and desorption time)...
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In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope
PublikacjaBACKGROUND. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans...
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Preferred Benchmarking Criteria for Systematic Taxonomy of Embedded Platforms (STEP) in Human System Interaction Systems
PublikacjaThe rate of progress in the field of Artificial Intelligence (AI) and Machine Learning (ML) has significantly increased over the past ten years and continues to accelerate. Since then, AI has made the leap from research case studies to real production ready applications. The significance of this growth cannot be undermined as it catalyzed the very nature of computing. Conventional platforms struggle to achieve greater performance...
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Social Capital, Human Capital, Tacit Knowledge, and Innovations: A Polish-US Cross-Country Study
PublikacjaThis study measures the relationship between human and social capital (internal and external) and tacit knowledge sharing's influence on innovativeness among knowledge workers employed in Polish (n=1050) and US (n=1118) organizations. The structural equation modeling method revealed that internal social capital matters more for organizational innovativeness in the US. In Poland, both external and internal were important. Specifically,...
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The influence of Nigella sativa essential oil on proliferation, activation, and apoptosis of human T lymphocytes in vitro
PublikacjaIn previous work, we tested the immunomodulatory effect of Nigella sativa (NS) fatty oil. Our results demonstrated that unrefined, obtained by cold pressing black cumin seed oil inhibited lymphocytes’ proliferation and induced their apoptosis in a dose-dependent manner. In this study, we examined the immunomodulatory properties of essential oil (EO) obtained from the NS seeds by hydrodistillation and its two main constituents:...
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Deep neural networks for human pose estimation from a very low resolution depth image
PublikacjaThe work presented in the paper is dedicated to determining and evaluating the most efficient neural network architecture applied as a multiple regression network localizing human body joints in 3D space based on a single low resolution depth image. The main challenge was to deal with a noisy and coarse representation of the human body, as observed by a depth sensor from a large distance, and to achieve high localization precision....
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Computer-Aided Greenery Design—Prototype Green Structure Improving Human Health in Urban Ecosystem
PublikacjaIncreasing population and urbanization, with climate change consequences, such as rising temperatures, influence public health and well-being. The search to improve the quality of life in cities becomes one of the priority objectives. A solution can be found in the role of greenery in an urban environment and its impact on human health. This opens a path toward experimentation on microclimate green structures that can be inserted...
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Long‐time scale simulations of virus‐like particles from three human‐norovirus strains
PublikacjaThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
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Analysis of volatile fraction of hybrid fruit pulp using Proton Transfer Reaction - Time-Of-Flight Mass Spectrometry
PublikacjaFruits and vegetables are important ingredients in human diet. Because of this, it is very important to know their exact composition and to control their quality. Based on the aroma of food products, it is possible to pre-evaluate their quality and freshness. The aim of this work was to characterize the volatile fraction of the hybrid fruit ‘sweetie’ using the modern analytical device PTR-TOFMS. Hybrid fruit samples are human-made...
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Oxidative stress in humans: validation of biomarkers of DNA damage
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Olfactory and tissue markers of fear in mammals including humans
PublikacjaW pracy przedstawiono informacje na temat:-klasyfikacji i budowy chemicznej związków chemicznych zaliczanych do grupy feromonów,-ich rola w funkcjonowaniu organizmów żywych w tym także organizmu ludzkiego,wyników badań prowadzonych z wykorzystaniem komory ekspozycyjnej własnej konstrukcji,metodyk analitycznych wykorzystywanych do oznaczania śladowych zawartości feromonów w próbkach wydychanego powietrza.
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Evidence for consolidation of neuronal assemblies after seizures in humans
PublikacjaThe establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...
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A study to identify olfactory markers of fear in rats and humans
PublikacjaW pracy przedstawiono wyniki wstępnych badań ukierunkowanych na wykrycie podstawowych fermonów wydzielanych w sytuacji zagrożenia (fermony alarmowe) przez różne organizmy żywe.W badaniach zastosowano takie techniki jak TD-GC-MS, SPME-GC-MS stwierdzono występowanie fermonów należących do takich klas związków organicznych jak alkohole, węglowodory nasycone, aldehydy, kwasy karboksylowe i ketony.
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What defines excellent lighting design for humans and animals?
PublikacjaWhat defines excellent lighting design for humans and animals? The answer to the above question is more than complex. It is not enough nowadays to design a project to make it aesthetically pleasing. Nor is it sufficient to create nicely lit environments, or simply to achieve the light levels required by the lighting norms or standards. With the new scientific research of the last few decades that relates directly or indirectly...
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Prebiotics and probiotics in food
PublikacjaNowadays, food is not only used to satisfy hunger and is a source of nutrients, but is also considered a factor that directly affects human health. Consumers are looking for high-quality products that contain bioactive ingredients that affect the proper functioning of the body and good mood. Functional foods, which must exhibit health benefits when consumed as part of a balanced diet, are becoming increasingly popular among health-conscious...
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Characteristics of blond and red star ruby jaffa graefruits (citrus paradisi):results of the studies in vitro, in vivo and on patients suffering from atherosclerosis
PublikacjaCelem projektu, którego wyniki opisano w pracy byly badania dwóch odmian (jasna i czerwona) owoców grejfruta (in vitro i in vivo) stosowanych jako suplement diety pacjentów cierpiących na arterioskleroze. Stwierdzono, że zawartość związków bioaktywnych a w szczególności zwiazakow fenolowych i lepsze właściwosci przeciwutelniajace wykazuja owoce jasnej odmiany grajfruta. Stosowanie diety z dodatkiem owoców czerownego grejfruta w...
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Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells
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Inhibition of phthalocyanine-sensitized photohemolysis of human erythrocytes by polyphenolic antioxidants: description of quantitative structure–activity relationships
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Erratum to: Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C
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Investigation of Iron and Zinc Concentrations in Human Milk in Correlation to Maternal Factors: An Observational Pilot Study in Poland
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Relation between polyphenols, malondialdehyde, antioxidant capacity, lactate dehydrogenase and toxic elements in human colostrum milk
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<p>Nanoparticles And Human Saliva: A Step Towards Drug Delivery Systems For Dental And Craniofacial Biomaterials</p>
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
PublikacjaA wide spectrum of brain rhythms are engaged throughout the human cortex in cognitive functions. How the rhythms of various low and high frequencies are spatiotemporally coordinated across the human brain during memory processing is inconclusive. They can either be coordinated together across a wide range of the frequency spectrum or induced in specific bands. We used a large dataset of human intracranial electroencephalography...
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
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Sequential induction of mitotic catastrophe followed by apoptosis in human leukemia MOLT4 cells by imidazoacridinone C-1311
PublikacjaWykazano, że pochodna imidazoakrydonu C-1311 indukuje zahamowanie progresji komórek MOLT4 w fazie G2M cyklu życiowego. Podwyższona ekspresja fosfoepitopu MPM-2 przy jednoczesnym zaniku ufosforylowanej formy Tyr15-cdc2 wskazywała, iż komórki początkowo zablokowane w fazie G2 przechodziły do mitozy. Jednocześnie na skutek nieprawidłowego przebiegu mitozy komórki ulegały katastrofie mitotycznej. Analiza biochenicznych markerów apoptozy...
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Changes in the Thickness of Ice Cover on Water Bodies Subject to Human Pressure (Silesian Upland, Southern Poland)
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IL-33 and IL-4 impair barrier functions of human vascular endothelium via different mechanisms
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The effect of interleukin-35 on the integrity, ICAM-1 expression and apoptosis of human aortic smooth muscle cells
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Immunoscore, circulating tumor cells and human-derived organoids as potential predictive tools in personalized cancer medicine
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Evaluation of a new freezing protocol containing 20% dimethyl sulphoxide concentration to cryopreserve human ovarian tissue
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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The response of human colon cancer cells to C-1748 (4-methyl-1-nitroacridine derivative) treatment
PublikacjaPrzeprowadzone badania miały na celu określenie wpływu pochodnej 4-metylo-1-nitroakrydyny C-1748 na komórki ludzkiego raka okrężnicy HCT8 oraz HT29. Komórki obu linii, traktowane badanym związkiem, ulegały przede wszystkim apoptozie, przy czym liczba komórek apoptotycznych była znacznie większa w przypadku linii HCT8. Ponadto, proliferacja części komórek HCT8, została zahamowana w wyniku uruchomienia procesu starzenia, czego nie...
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Characterization and cytotoxic effect of aqua-(2,2′,2′′-nitrilotriacetato)-oxo-vanadium salts on human osteosarcoma cells
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Selected extracts from Potentilla alba modulate the viability of normal and cancerous cells of the human colon epithelium
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Potentilla alba Extracts Affect the Viability and Proliferation of Non-Cancerous and Cancerous Colon Human Epithelial Cells
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Anticancer potential of acetone extracts from selected Potentilla species against human colorectal cancer cells
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