Filtry
wszystkich: 3182
wybranych: 2926
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: elliptic potential
-
Antitumor Activity of Triazine Mimic Antibiotics for DNA-binding Implications (Impressive Activity in Vitro Against a Variety of Tumor Types in the NCI-60 Screen): NSC 710607 To Fight HCT-116 Human Colon Carcinoma Cell Lines in Vivo Using the Hollow Fiber Assay and Xenograft Mouse Models
PublikacjaPurpose Successful clinical applications of DNA-directed selective cytotoxic agents disrupt the vital replication/transcription processes and ultimately lead to cancer cell death. This study aimed to examine the growth screen of two lead triazine compounds in a number of cell lines and xenografts and to develop anticancer agents with noncovalent binding affinity bringing fewer side effects. Methods The NCI initial hollow...
-
Investigation of rotational state-changing collisions of C2N− ions with helium
PublikacjaThe cross sections for rotational inelastic collisions between atoms and a molecular anion can be very large, if the anion has a dipole moment. This makes molecular anions very efficient in cooling atomic gases. We address rotational inelastic collisions of Helium atoms with the molecular anion C2N–. Here we present preliminary calculations of the potential energy surface.
-
Management of MV/LV Transformer Replacement Based on AMI Platform
PublikacjaThe paper presents the extended possibilities of managing the selection and replacement of MV/LV transformers using the measurement data from the Advanced Metering Infrastructure (AMI) system. The analysis was conducted on samples of over 1900 transformers that operate in two different types of MV grids: rural and urban. The analysis has shown that there is a great potential in the field of optimizing the rated power of the transformers.
-
A New Quaternion Encryption Scheme for Image Transmission
PublikacjaQuaternions are hypercomplex number of rank 4. They are often applied to mechanics in three-dimensional space and considered as one of the best ways to represent rotations. In this paper a new encryption scheme, based on the rotation of data vector in three-dimensional space around another quaternion (key) is proposed. A computer-based simulation was created to analyze the potential of the proposed encryption technique.
-
Balance recognition on the basis of EEG measurement.
PublikacjaAlthough electroencephalography (EEG) is not typically used for verifying the sense of balance, it can be used for analysing cortical signals responsible for this phenomenon. Simple balance tasks can be proposed as a good indicator of whether the sense of balance is acting more or less actively. This article presents preliminary results for the potential of using EEG to balance sensing....
-
On Explaining Intuitiveness of Software Engineering Techniques with User eXperience Concepts
PublikacjaW referacie zawarto próbę wyjaśnienia intuicyjności technik inżynierii oprogramowania za pomocą pojęć zaczerpniętych z obszaru doświadczenia użytkownika. Analizy dotyczą zarówno intuicyjności przy pierwszym zetknięciu się użytkownika z daną techniką, jak i dynamiki transformacji epizodycznych doświadczeń na doświadczenie skumulowane i powiązane z nim postrzeganie intuicyjności. Przedyskutowano potencjalne zastosowania modelu i...
-
Homoclinics for singular strong force Lagrangian systems
PublikacjaWe study the existence of homoclinic solutions for a class of generalized Lagrangian systems in the plane, with a C1-smooth potential with a single well of infinite depth at a point ξ and a unique strict global maximum 0 at the origin.Under a strong force condition around the singular point ξ, via minimization of an action integral, we will prove the existence of at least two geometrically distinct homoclinic solutions.
-
Krylov Space Iterative Solvers on Graphics Processing Units
PublikacjaCUDA architecture was introduced by Nvidia three years ago and since then there have been many promising publications demonstrating a huge potential of Graphics Processing Units (GPUs) in scientific computations. In this paper, we investigate the performance of iterative methods such as cg, minres, gmres, bicg that may be used to solve large sparse real and complex systems of equations arising in computational electromagnetics.
-
Workbook for cooperative development of personnell and organisation for innovation in SME in the Baltic Sea Region
PublikacjaThis study highlights the potential for cooperative development of personnel and organisational innovations in SMEs and gives an example implemented by the University of Lund together with the Municipality of Astorp and local companies. This innovation field is of particular importance for all companies in the region, since it does apply to any professional sector, be it a service oriented company or a manufacturing business. This...
-
Elastic distortional buckling of thin-walled bars of closed quadratic cross-section
PublikacjaIn this study a thin-walled bar with closed quadratic cross-section is considered. The elastic stability of axially compressed bar related to the cross-section distortion is investigated. The governing differential equation is derived with aid of the principle of stationary total potential energy. The critical load for the simply supported bar is found in analytical form and it is compared with the FEM solution. Sufficient accuracy...
-
RECENT ADVANCES IN GRAPHENE APPLICATION FOR ELECTRONIC SENSING
PublikacjaThe great interest in graphene is caused by its potential for constructing various sensors exhibiting excellent parameters. The high carrier mobility and the unique band structure of graphene makes it promising especially in the field-effect transistors (GFET) applications. In this article, recent advances of the selected graphene-based sensor applications were presented and the possible directions for further investigations were...
-
Green function diagonal for a class of heat equations
PublikacjaA construction of the heat kernel diagonal is considered as element of generalized zeta function theory, which gradient at the origin defines determinant of a differential operator in a technique for regularizing quadratic path integral. Some classes of explicit expressions of the Green function in the case of finite-gap potential coefficient of the heat equation are constructed. An algorithm and program for Mathematica are presented...
-
Elastic distortional buckling of thin-walled bars of closed quadratic cross-section
PublikacjaIn this study a tin-walled bar with closed quadratic cross-section is considered. The elastic stability of axially compressed bar related to the cross-section distortion is investigated. The governing differential equatio is derived with aid of the principle of stationary potential energy. The critical load for simply supported bar is found in an analytical form and it is copared with the FEM solution. Sufficient accuracy of the...
-
Urine headspace analysis in medical diagnostics
PublikacjaThe analysis of the volatile organic compounds in the bodily fluids such as urine may provide useful information on the patients’ general health. The potential application of urine headspace analysis could facilitate the diagnostics of various diseases such as metabolic disorders, urinary tract diseases and gastrointestinal conditions. Described in this paper are the currently available techniques of urine sample analysis as well...
-
Prospects of ionic liquids application in electronic and bioelectronic nose instruments
PublikacjaThis paper addresses the problem of application of ionic liquids to chemical sensors and biosensors being an integral part of the electronic and bioelectronic-type instruments. The design and principle of operation of the electronic and bioelectronic noses are compared. Both the benefits and shortcomings of the application of ionic liquids in these type of instruments are described. The prospects of the development and application...
-
Inhibition of Polymer Photodegradation by Incorporation of Coffee Silverskin
PublikacjaOver the last years, the trend associated with the incorporation of materials from renewable resources into polymer technology is getting significantly more vital. Researchers are trying to transfer the properties of natural raw materials into the polymer world. Therefore, different natural materials are more often investigated as potential additives for polymers. Such an effect is noted for the coffee industry by-products, such...
-
The Method of Selecting the Interval of Functional Tests Taking into Account Economic Aspects and Legal Requirements
PublikacjaThe article discusses the problem of choosing the optimal frequency of functional tests, taking into account the reliability and law requirements, but also the impact of business aspects in the company. The subject of functional test interval is well described for purposes of the process industry. Unfortunately, this is not the case for the machinery safety functions with low demand mode. This is followed by a presentation of the...
-
Novel Structures and Applications of Graphene-Based Semiconductor Photocatalysts: Faceted Particles, Photonic Crystals, Antimicrobial and Magnetic Properties
PublikacjaGraphene, graphene oxide, reduced graphene oxide and their composites with various compounds/materials have high potential for substantial impact as cheap photocatalysts, which is essential to meet the demands of global activity, offering the advantage of utilizing “green” solar energy. Accordingly, graphene-based materials might help to reduce reliance on fossil fuel supplies and facile remediation routes to achieve clean environment...
-
Theoretical studies of fragmentation processes of neutral and ionized furan molecule
PublikacjaThis PhD thesis focuses on the fragmentation mechanism of the furan molecule in the gas phase. The approach taken in this work comprised of three theoretical methodologies considering the dynamical, energetical and entropic aspects of the studied process. First, molecular dynamics simulations were performed. Next, the potential energy surfaces were explored at the DFT/B3LYP level of theory. Finally, a new statistical Microcanonical...
-
Fragmentomic analysis of biopeptides in silico released from milk proteins
PublikacjaThe fragmentomic-assisted method was employed to predict the biological potential of peptides derived from milk proteins hydrolyzed by papain and bromelain. Firstly, protein sequences were acquired from the BIOPEP-UWM database and then hydrolyzed by the above enzymes using a BIOPEP-UWM tool called “Enzyme(s) action”. The released peptides were defined as parent peptides and further analyzed for the presence of shorter peptidic...
-
In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2
PublikacjaThe recent global pandemic caused by COVID-19 has triggered an intense effort worldwide towards the development of an effective cure for this disease. In our effort we have explored the 2-alkynyl substituted 3-chloropyrazine framework as a potential template for the design of molecules for this purpose. Our strategy was supported by the in silico studies of representative compounds to assess their binding affinities via docking...
-
Improving the regulation of the derivatives market as an objective prerequisite for sustainable development of the global financial system
PublikacjaThe development of financial markets is characterized by the emergence of new financial instruments, in particular derivatives, the risk level analysis of which is complicated. Counterparties are not always fully aware of and do not adequately assess the potential risks of derivatives, which may lead to large financial losses and sometimes bankruptcies. The purpose of the study is to generalize approaches to regulating derivative...
-
Nanocrystalline diamond sheets as protective coatings for fiber-optic measurement head
PublikacjaFiber-optic sensors find numerous applications in science and industry, but their full potential is limited because of the risk of damaging the measurement head, in particular, due to the vulnerability of unprotected tips of the fiber to mechanical damage and aggressive chemical agents. In this paper, we report the first use of a new nanocrystalline diamond structure in a fiber-optic measurement head as a protective coating of...
-
Customer Engagement Consequences for Firms
PublikacjaPurpose: Customer engagement (CE) is a customers’ voluntary resource contribution to firms’ functions, and it goes beyond transactions during customers’ behavioral manifestations toward the brand or firm’s offerings or activities. The effective CE management requires to understand the potential CE effects, and leverage the potential benefit and threat of CE, however negative consequences or risks of CE have remained unexplored...
-
Speciation of heavy metal compounds in samples of biota from marine ecosystems
PublikacjaIt has become increasingly evident that the toxicity, mobility, bioavailability and bioaccumulation of metals are dependent on the particular physico-chemical form in which the element occurs in the environment. Special attention is paid to metals, which are essential for the proper functioning of organisms if present in appropriate amounts but are toxic if in excess (i.e. Se, Cr, Zn), and also to non-essential elements (i.e. Hg,...
-
Sense of safety and opinions about COVID-19 vaccinations in Polish school teachers: The role of conspiracy theories belief and fear of COVID-19
PublikacjaThe co-occurrence of COVID-19 conspiracy theories (CCT) and fear of the coronavirus (FCV) can be linked to how safe people feel and how much they endorse vaccinations. School teachers were one of the vaccination priority groups in Poland. We conducted three cross-sectional studies (N1 = 1006; N2 = 1689; N3 = 627) to find out the potential interactive effects of CCT belief and FCV in predicting sense of safety (SoS; Studies 1-3),...
-
Finding the Right Solvent: A Novel Screening Protocol for Identifying Environmentally Friendly and Cost-Effective Options for Benzenesulfonamide
PublikacjaThis study investigated the solubility of benzenesulfonamide (BSA) as a model compound using experimental and computational methods. New experimental solubility data were collected in the solvents DMSO, DMF, 4FM, and their binary mixtures with water. The predictive model was constructed based on the best-performing regression models trained on available experimental data, and their hyperparameters were optimized using a newly...
-
The influence of roasting and additional processing on the content of bioactive components in special purpose coffees
PublikacjaCoffee being the beverage consumed worldwide is also a very competitive commodity. Consequently, producers seek ways of attracting consumers by proposing e.g. novel ingredient combinations usually without evaluating their health quality. In this study, variations in health-promoting determinants for five special purpose coffee brews were characterized. The major bioactive components - chlorogenic acids (CAs) - detected by HPLC-DAD-MS...
-
Serum bisphenol A concentrations correlate with serum testosterone levels in women with polycystic ovary syndrome
PublikacjaThe aim of this study was to determine serum bisphenol A (BPA) concentrations using high performance liquid chromatography with tandem mass spectrometry (HPLC–MS/MS) in women with polycystic ovary syndrome (PCOS) (n=106, age range 18–40 yrs) and to evaluate its potential impact on their hormonal and metabolic profile. The control group consisted of age- and BMI-matched 80 eumenorrheic women with no clinical or biochemical hyperandrogenism....
-
Photoinduced electron transfer in 5-bromouracil labeled DNA. A contrathermodynamic mechanism revisited by electron transfer theories
PublikacjaThe understanding of the 5-bromouracil (BrU) based photosensitization mechanism of DNA damage is of large interest due to the potential applications in photodynamic therapy. Photoinduced electron transfer (ET) in BrU labeled duplexes comprising the 50 -GBrU or 50 -ABrU sequence showed that a much lower reactivity was found for the 50 -GBrU pattern. Since the ionization potential of G is lower than that of A, this sequence selectivity...
-
Endocrine Disrupting Compounds – Problems and Challenges
PublikacjaIn this chapter, information about some of the estrogenic compounds and their environmental fate and biological influence can be found. Special attention is paid to the review of the analytical approaches used at the stages of detection and determination of Endocrine Disrupting Compounds (EDCs) in the environmental samples. Also, a brief characterization of both cellular and non-cellular bioassays is presented. The discovery of...
-
Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated /N-Tiophosphorylated Tacrine
PublikacjaNovel phosphorus and thiophosphorus tacrine derivatives were designed, synthesized and their biological activity and molecular modeling was investigated as a new potential anti-Alzheimer's disease (AD) agents. All new synthesized compound exhibited lower toxicity against neuroblastoma cell line (SH-SY5Y) in comparison with tacrine. Two analogues in the series, 7 and 9, demonstrated lack of cytotoxicity against hepatocellular cells...
-
Solventless sample preparation techniques based on solid- and vapour-phase extraction
PublikacjaThe main objective of this review is to critically evaluate recent developments in solventless sample preparation techniques. The potential of a variety of sample preparation techniques based on solid- and vapour-phase extraction techniques is evaluated. Direct thermal extraction and derivatization processes to facilitate the extraction of analytes in different areas are included. The applicability, disadvantages and advantages...
-
Application of electrochemical sensors and sensor matrixes for measurement of odorous chemical compounds
PublikacjaIn this paper describes the principle of operation of the electrochemical sensors and the sensor matrixes comprised of electrochemical sensors intended for measurement of odorous compounds. Critical comparison of these sensors’ advantages and disadvantages has been made. The fields of economy contributing to release of odours and the potential sources of their emission have been identified. Commercially available electrochemical...
-
Homoclinic orbits for a class of singular second order Hamiltonian systems in ℝ3
PublikacjaWe consider a conservative second order Hamiltonian system \ddot{q}+ ∇V(q)=0 in R3 with a potential V having a global maximum at the origin and a line l ∩ {0} = ∅ as a set of singular points. Under a certain compactness condition on V at infinity and a strong force condition at singular points we study, by the use of variational methods and geometrical arguments, the existence of homoclinic solutions of the system.
-
Distortional buckling of thin-walled columns of closed quadratic cross-section
PublikacjaThe elastic stability of axially compressed column related to the cross-section distortion is investigated. Two kinds of closed quadratic cross-sections are taken into consideration with internal walls and without it. The governing differential equation is derived with aid of the principle of stationary total potential energy. The critical loads for the simply supported columns are found in an analytical form and compared with...
-
Commercially produced and modified starches
PublikacjaThis book presents some fascinating phenomena associated with the remarkable features of high performance polymers and also provides an update on applications of modern polymers. It offers new research on structure–property relationships, synthesis and purification, and potential applications of high performance polymers. The collection of topics in this book reflects the diversity of recent advances in modern polymers with a broad...
-
How to stop salami science: promotion of healthy trends in publishing behavior
PublikacjaThe career of scientists often depends on the number of their published works. This fact leads to the overproduction of low quality papers burying the important articles and making the knowledge less accessible. One of the methods to counteract these negative aspects might lie in the promotion of healthy trends in publishing behavior. In the present work, the theoretical analysis of a new bibliometric measure is presented, and...
-
Chemiresistive gas sensors based on carbon nanotubes - fabrication and application
PublikacjaMany types of sensors have been invented to identify and quantify chemical contamination in the gas phase. Sensors based on carbon nanotubes are particularly attractive because of their wide range of applicaions and potential use in electronic nose that can be controlled using algorithms of Artificial Intelligence. Sensor functions, fabrication and selected applications are reviewed and discussed with focus on chemiresistors. Drawbacks...
-
Dissecting gamma frequency activities during human memory processing
PublikacjaGamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not...
-
The effect of impacted third molars on second molar external root resorption, a cross-sectional cone beam computed tomography study
PublikacjaBackground: Third molars have the highest prevalence of impaction in teeth and can cause pathological damage on the adjacent second molars. This study aims to evaluate the effects of factors related to impacted third molars on external root resorption (ERR) in adjacent second molars using cone-beam computed tomography (CBCT). Material and Methods: In CBCTs, the effect of impacted third molars on the root surface of adjacent second...
-
Voltage Conditions in Low Voltage Grid with Connected Mictogeneration
PublikacjaThe introduction of distributed generation into a low voltage grid may cause voltage problems in it. The paper discusses the effect of microgeneration on voltage levels in a low voltage grid. A real low voltage grid of considerable length was selected for the analysis. The grid primarily supplies residential buildings in a rural area. Results of tests that consider potential measures which could be applied in this grid to improve...
-
Impact of polder flood plain of the Cisowska Struga on the transformation of flood waves between Gdynia and Rumia
PublikacjaThe paper presents the results of hydraulic calculations (numerical simulations), which were made to investigate the role of floodplain (polder) adjacent to the left bank of Cisowska Struga in Gdynia downstream Hutnicza St. in the process of retention and transformation of flood waves occurring in this river due to torrential rainfall. The paper also addressed the issue of the impact of potential changes in the development of the...
-
Juices from untypical edible fruits as acidity regulators for food industry. Verification of health promoting properties. Comparison with typical acidity regulators
PublikacjaThe purpose of this work was to verify possibility of using juices from selected fruits characterized by the high antioxidant potential as natural acidity regulators with improved nutritional properties. The tested fruits included: mirabelle plum, sea buckthorn, lemon and blueberry honeysuckle.The potentiometric titration was used to compare the effiacy of the juices as acidity regulators with citric acid, a widely used acidity...
-
Two families of infinitely many homoclinics for singular strong force Hamiltonian systems
PublikacjaWe are concerned with a planar autonomous Hamiltonian system with a potential possessing a single well of infinite depth at a point X and a unique strict global maximum 0 at a point A. Under a strong force condition around the singularity X, via minimization of an action integral and using a shadowing chain lemma together with simple geometrical arguments, we prove the existence of infinitely many geometrically distinct homoclinic...
-
Three-dimensional conceptual model for service-oriented simulation
Publikacjan this letter, we propose a novel three-dimensional conceptual model for an emerging service-oriented simulation paradigm. The model can be used as a guideline or an analytic means to find the potential and possible future directions of the current simulation frameworks. In particular, the model inspects the crossover between the disciplines of modeling and simulation, service-orientation, and software/systems engineering. Finally,...
-
Performance and emission characteristics of diesel engines running on gaseous fuels in dual-fuel mode
PublikacjaConventional fossil fuels are being substituted with alternative green fuels because of their greenhouse gas emissions and pollution problems, which pose a severe threat to the environment. Several studies have reported the usage of biodiesel and gaseous fuels in both single and dual-fuel modes. Gaseous fuels such as producer gas, biogas, syngas, and hydrogen produced from renewable biomass could potentially be used along with...
-
Polyurethane based hybrid ciprofloxacin-releasing wound dressings designed for skin engineering purpose
PublikacjaPurpose Even in the 21st century, chronic wounds still pose a major challenge due to potentially inappropriate treatment options, so the latest wound dressings are hybrid systems that enable clinical management, such as a hybrid of hydrogels, antibiotics and polymers. These wound dressings are mainly used for chronic and complex wounds, which can easily be infected by bacteria. Materials and methods Six Composite Porous Matrices...
-
Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
PublikacjaAn important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...
-
Environmental characteristics of a tundra river system in Svalbard. Part 2: Chemical stress factors
PublikacjaBacterial communities in the Arctic environment are subject to multiple stress factors, including contaminants, although typically their concentrations are small. The Arctic contamination research has focused on persistent organic pollutants (POPs) because they are bioaccumulative, resistant to degradation and toxic for all organisms. Pollutants have entered the Arctic predominantly by atmospheric and oceanic long-range transport,...