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Search results for: entrepreneurial self- efficacy
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Safety and efficacy of lenabasum in a phase 2 randomized, placebo-controlled trial in adults with cystic fibrosis
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Efficacy of daratumumab monotherapy in real-world heavily pretreated patients with relapsed or refractory multiple myeloma
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Improved-Efficacy EM-Based Antenna Miniaturization by Multi-Fidelity Simulations and Objective Function Adaptation
PublicationThe growing demands for integration of surface mount design (SMD) antennas into miniatur-ized electronic devices have been continuously imposing limitations on the structure dimen-sions. Examples include embedded antennas in applications such as on-board devices, picosatel-lites, 5G communications, or implantable and wearable devices. The demands for size reduction while ensuring a satisfactory level of the electrical and field...
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Testing Question Order Effects of Self-perception of Risk Propensity on Simple Lottery Choices as Measures of the Actual Risk Propensity
PublicationUncertainty together with the necessity of making choices inevitably results in risky decisions. For many years now, scientists have been studying notions connected with risk such as risk management, risk perception or risk propensity. While many sophisticated methods regarding measurement of risk propensity have been developed so far, it seems that little attention has been paid to checking whether they are not inherently flawed....
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Development and evaluation of RADA-PDGF2 self-assembling peptide hydrogel for enhanced skin wound healing
PublicationBackground: Wound healing complications affect numerous patients each year, creating significant economic and medical challenges. Currently, available methods are not fully effective in the treatment of chronic or complicated wounds; thus, new methods are constantly sought. Our previous studies showed that a peptide designated as PDGF2 derived from PDGF-BB could be a promising drug candidate for wound treatment and that RADA16-I...
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Self-Organization of Graft Copolymers and Retortable iPP-Based Nanoporous Films Thereof
PublicationPolyolefins might become inexpensive alternatives to the existing membranes based on polyethersulfone. Here we disclose the production of retortable, well-defined PP-based nanoporous membranes derived from amphiphilic graft copolymer precursors. The graft copolymers, containing a polypropylene backbone and polyester grafts, were obtained by grafting lactones, specifically δ-valerolactone and ε-caprolactone, from well-defined randomly...
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Optimization of Self-Organized TiO2 Nanotube Geometry on Ti and Ti Alloys Using Fuzzy Logic Reasoning
PublicationThe geometry of self-organized TiO2 nanotubes, obtained by electrochemicalanodization, has been determined by using fuzzy reasoning approach. The efficiency of TiO2nanotubular layer in biomedical applications depends on geometry and available surface area ofnanotubes, which can be determined by their diameter and length. The structure of nanotubesdepends on processing parameters of electrochemical anodization, like applied potential,anodization...
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An algorithmic approach to estimating the minimal number of periodic points for smooth self-maps of simply-connected manifolds
PublicationFor a given self-map f of M, a closed smooth connected and simply-connected manifold of dimension m 4, we provide an algorithm for estimating the values of the topological invariant D^m_r [f], which equals the minimal number of r-periodic points in the smooth homotopy class of f. Our results are based on the combinatorial scheme for computing D^m_r [f] introduced by G. Graff and J. Jezierski [J. Fixed Point Theory Appl. 13 (2013),...
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Propulsion and Maneuvering Systems’ Characteristics of the U.S. Flagged Great Lakes Self-Unloading Bulk Carriers
PublicationPaper contains an overview of the propulsion and maneuvering systems’ characteristics of United States flagged Great Lakes self - unloading bulk carriers. A contrast between the importance of the transport task carried by those vessels to their low number and considerable age suggests the need to review and understand their complexity as well as complexity of their operations in order to provide suitable energy- and operational...
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Multifrequency self-optimizing narrowband interference canceller
PublicationThe problem of cancellation of a nonstationary sinusoidal interference, acting at the output of a linear stable plant, is considered. It is assumed that disturbance is a multifrequency narrowband signal, and that system output is contaminated with wideband noise. It is not assumed that the reference signal is available. Two disturbance cancelling schemes are proposed, one for disturbances with unrelated frequency components, and...
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Modelling gene expression of a self-regulating protein
PublicationWe analyze a model of gene transcription and protein synthesis. We take into account the number of sites on the protein’s promoter at which the protein’s dimers can bind blocking transcription of protein mRNA.
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Isolation and Self-Association Studies of Beta-Lactoglobulin
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Coupledfield modelling of interferometric hydrophone with self supportedmandrel.
PublicationW pracy przedstawiono nowatorską konstrukcję światłowodowego interferometrycznego przetwornika ciśnienia do zastosowań w hydrofonach. Przetwornik ten składa się z cewki światłowodowej zalanej w żywicy epoksydowej. Zaprezentowano technikę modelowania właściwości przetwornika, wykorzystującą opis przy pomocy parametrów równoważnego materiału ortotropowego i Metodę Elementów Skończonych. Przestawiono wyniki statycznego modelowania...
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Energy optimisation in resilient self-stabilizing processes
PublicationW pracy rozważa się rozproszony model obliczeń, w którym struktura systemu jest reprezentowana przez graf bezpośrednich połączeń komunikacyjnych. W tym modelu podajemy nowy samostabilizujący algorytm kolorowania grafów oparty na konstrukcji drzewa spinającego. Zgodnie z naszą wiedzą jest to pierwszy algorytm z gwarantowaną wielomianową liczbą ruchów, który dokładnie koloruje grafy dwudzielne.
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Self-stabilizing algorithm for edge-coloring of graphs
PublicationReferat ten poświęcony jest kolorowaniu grafów w modelu rozproszonym.Podano samostabilizujący się algorytm kolorowania krawędzi grafu wraz z dowodem poprawności oraz oszacowaniem jego czasu działania.
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Psychophysiological strategies for enhancing performance through imagery – skin conductance level analysis in guided vs. self-produced imagery
PublicationAthletes need to achieve their optimal level of arousal for peak performance. Visualization or mental rehearsal (i.e., Imagery) often helps to obtain an appropriate level of activation, which can be detected by monitoring Skin Conductance Level (SCL). However, different types of imagery could elicit different amount of physiological arousal. Therefore, this study aims: (1) to investigate differences in SCL associated with two instructional...
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Microfluidic SIW-Based Tunable Self-Diplexing Antenna for Sub-6 GHz Band Applications
PublicationThis work introduces a novel frequency tunable self-diplexing antenna (SDA) design based on substrate integrated waveguide (SIW) technology. A modified A-shaped slot is employed on the cavity’s top plane, which is excited by two independent 50 Ω microstrip feed lines to operate at each resonant frequency. The frequency flexibility of the proposed antenna allows for fine-tuning at each resonance frequency. The frequency flexibility...
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Shielded HMSIW-Based Self-Triplexing Antenna With High Isolation for WiFi/WLAN/ISM Band
PublicationThis article presents a novel design of a miniaturized self-triplexing antenna (STA) based on the shielded half-mode substrate integrated waveguide (S-HMSIW) for WiFi/WLAN/ISM-band applications. The S-HMSIW is constructed by assembling one row of vias and an open slot at the open-ended side of the conventional HMSIW. This configuration increases the quality factor and minimizes unwanted radiation loss, which allows for achieving...
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Highly Miniaturized Self-Diplexed U-Shaped Slot Antenna Based on Shielded QMSIW
PublicationThis article presents an efficient yet simple design approach to highly miniaturized cavity-backed self-diplexing antenna (SDA) with high-isolation. The structure employs a shielded quarter-mode substrate integrated waveguide (QMSIW). Two U-shaped slots are engraved on the top conducting plane, which realize two frequency bands and significant size reduction. The slots are excited by two independent 50Ω orthogonal feed-lines to...
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Computations of the least number of periodic points of smooth boundary-preserving self-maps of simply-connected manifolds
PublicationLet $r$ be an odd natural number, $M$ a compact simply-connected smooth manifold, $\dim M\geq 4$, such that its boundary $\partial M$ is also simply-connected. We consider $f$, a $C^1$ self-maps of $M$, preserving $\partial M$. In [G. Graff and J. Jezierski, Geom. Dedicata 187 (2017), 241-258] the smooth Nielsen type periodic number $D_r(f;M,\partial M)$ was defined and proved to be equal to the minimal number of $r$-periodic points...
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Algebraic periods and minimal number of periodic points for smooth self-maps of 1-connected 4-manifolds with definite intersection forms
PublicationLet M be a closed 1-connected smooth 4-manifolds, and let r be a non-negative integer. We study the problem of finding minimal number of r-periodic points in the smooth homotopy class of a given map f: M-->M. This task is related to determining a topological invariant D^4_r[f], defined in Graff and Jezierski (Forum Math 21(3):491–509, 2009), expressed in terms of Lefschetz numbers of iterations and local fixed point indices of...
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Combinatorial scheme of finding minimal number of periodic points for smooth self-maps of simply connected manifolds
PublicationLet M be a closed smooth connected and simply connected manifold of dimension m at least 3, and let r be a fixed natural number. The topological invariant D^m_r [f], defined by the authors in [Forum Math. 21 (2009), 491-509], is equal to the minimal number of r-periodic points in the smooth homotopy class of f, a given self-map of M. In this paper, we present a general combinatorial scheme of computing D^m_r [f] for arbitrary dimension...
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Unsupervised Learning for Biomechanical Data Using Self-organising Maps, an Approach for Temporomandibular Joint Analysis
PublicationWe proposed to apply a specific machine learning technique called Self-Organising Maps (SOM) to identify similarities in the performance of muscles around human temporomandibular joint (TMJ). The performance was assessed by measuring muscle activation with the use of surface electromyography (sEMG). SOM algorithm used in the study was able to find clusters of data in sEMG test results. The SOM analysis was based on processed sEMG...
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Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes
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Antihypertensive efficacy and safety of olmesartan and ramipril in elderly patients with mild to moderate systolic and diastolic essential hypertension
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The processing of staphylococcal biofilm images from Fluorescence and Confocal Microscopy to assess in vitro efficacy of antiseptic molecules
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Improved Efficacy Behavioral Modeling of Microwave Circuits through Dimensionality Reduction and Fast Global Sensitivity Analysis
PublicationBehavioral models have garnered significant interest in the realm of high-frequency electronics. Their primary function is to substitute costly computational tools, notably electromagnetic (EM) analysis, for repetitive evaluations of the structure under consideration. These evaluations are often necessary for tasks like parameter tuning, statistical analysis, or multi-criterial design. However, constructing reliable surrogate models...
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Exploring the Antitumor Efficacy of N-Heterocyclic Nitrilotriacetate Oxidovanadium(IV) Salts on Prostate and Breast Cancer Cells
PublicationThe crystal structures of two newly synthesized nitrilotriacetate oxidovanadium(IV) salts, namely [QH][VO(nta)(H2O)](H2O)2 (I) and [(acr)H][VO(nta)(H2O)](H2O)2 (II), were determined. Additionally, the cytotoxic effects of four N-heterocyclic nitrilotriacetate oxidovanadium(IV) salts— 1,10-phenanthrolinium, [(phen)H][VO(nta)(H2O)](H2O)0.5 (III), 2,2′-bipyridinium [(bpy)H][VO(nta)(H2O)](H2O) (IV), and two newly synthesized compounds...
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Self-Organising map neural network in the analysis of electromyography data of muscles acting at temporomandibular joint.
PublicationThe temporomandibular joint (TMJ) is the joint that via muscle action and jaw motion allows for necessary physiological performances such as mastication. Whereas mandible translates and rotates [1]. Estimation of activity of muscles acting at the TMJ provides a knowledge of activation pattern solely of a specific patient that an electromyography (EMG) examination was carried out [2]. In this work, a Self-Organising Maps (SOMs)...
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Self-assembly of vertically oriented graphene nanostructures: multivariate characterisation by Minkowski functionals and fractal geometry
PublicationThe enormous self-assembly potential that graphene and its derived layered materials offer for responding to the contemporary environmental challenges has made it one of the most investigated materials. Hence, tuning its extraordinary properties and understanding the effect at all scales is crucial to tailoring highly customised electrodes. Vertically oriented graphene nanostructures, also known as carbon nanowalls (CNWs), due...
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Novel approach to ecotoxicological risk assessment of sediments cores around the shipwreck by the use of self-organizing maps
PublicationMarine and coastal pollution plays an increasingly important role due to recent severe accidents which drew attention to the consequences of oil spills causing widespread devastation of marine ecosystems. All these problems cannot be solved without conducting environmental studies in the area of possible oil spill and performing chemometric evaluation of the data obtained looking for similar patterns among pollutants and optimize...
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Chlorinated solvents in a petrochemical wastewater treatment plant: Anassessment of their removal using self-organising maps
PublicationThe self-organising map approach was used to assess the efficiency of chlorinated solvent removal frompetrochemical wastewater in a refinery wastewater treatment plant. Chlorinated solvents and inorganicanions (11 variables) were determined in 72 wastewater samples, collected from three different purificationstreams. The classification of variables identified technical solvents, brine from oil desalting andrunoff sulphates as pollution...
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Service and Path Discovery Extensions for Self-forming IEEE 802.11s Wireless Mesh Systems
PublicationWith the rapid growth of the quantity and capabilities of end-user electronic devices, both stationary and mobile, they are employed in increasing number of applications. In this situation, wireless network technologies begin to play a crucial role as networks access technologies, as cable-based solutions tend to be of limited utility in case of easily portable or mobile devices. Resulting development of wireless technologies reached...
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Frequency-Reconfigurable Hybrid SIW-Based Self-Diplexing Antenna Using Solid and Liquid Dielectric Loading
PublicationThis paper presents a novel frequencyreconfigurable self-diplexing antenna (SDA) utilizing a hybrid substrate-integrated waveguide (SIW). The antenna comprises a radiating slot, a feeding network, and a hybrid SIW cavity featuring half-mode circular and half-mode rectangular SIW structures. The unique feature of this antenna lies in its fine-tuning capability of each resonant frequency by inserting or injecting solid and liquid...
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Comparative Study of Self-Organizing Maps vs. Subjective Evaluation of Quality of Allophone Pronunciation for Nonnative English Speakers
PublicationThe purpose of this study was to apply Self-Organizing Maps to differentiate between the correct and the incorrect allophone pronunciations and to compare the results with subjective evaluation. Recordings of a list of target words, containing selected allophones of English plosive consonants, the velar nasal and the lateral consonant, were made twice. First, the target words were read from the list by 9 non-native speakers and...
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Self-organization of imidazolium ionic liquids in aqueous solution
PublicationW pracy przeanalizowano i podsumowano wyniki badań nad samoorganizacją oraz tworzeniem micel cieczy jonowych w roztworach wodnych otrzymane przez wiele zespołów badawczych. Średnio i długołańcuchowe imidazoliowe ciecze jonowe wykazują aktywność powierzchniową zależną od długości łańcucha alkilowego w kationie, analogicznie do kationowych surfaktantów. Wskazano na liczne zagadnienia, które wymagają dalszych systematycznych badań
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A probabilistic concept of load assessment of self-ignition engines
PublicationPrzedstawiono propozycję probabilistycznej interpretacji obciążenia silników spalinowych o zapłonie samoczynnym. Zaproponowano probabilistyczny opis obciążenia tych silników z uwzględnieniem znanych parametrów (wskaźników) ich pracy. Wykazano, że obciążenie tego rodzaju silników, rozpatrywane w dowolnej chwili, może być uważane za zmienną losową. Zwrócono uwagę, że obciążenie to może być uważane za zmienną losową wielowymiarową....
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Transfrontier co-operation of self-governments in Euroregion Baltic
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A self-optimization mechanism for generalized adaptive notch smoother
PublicationTracking of nonstationary narrowband signals is often accomplished using algorithms called adaptive notch filters (ANFs). Generalized adaptive notch smoothers (GANSs) extend the concepts of adaptive notch filtering in two directions. Firstly, they are designed to estimate coefficients of nonstationary quasi-periodic systems, rather than signals. Secondly, they employ noncausal processing, which greatly improves their accuracy and...
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Asynchronous and self-organizing radiolocation system — AEGIR
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Generalized adaptive notch filter with a self-optimization capability
PublicationW pracy przedstawiono samonastrajalny wariant tzw. uogólnionego adaptacyjnego filtru wycinającego. Automatycznym strojeniem objęte są dwa współczynniki wzmocnienia adaptacji, odpowiedzialne za śledzenie amplitud i częstotliwości parametrów identyfikowanego obiektu.
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Process of self-ignition engine loads and its properties
PublicationW artykule zaproponowano probabilistyczną interpretację obciążenia silników spalinowych o zapłonie samoczynnym z uwzględnieniem znanych parametrów (wskaźników) ich pracy. Wykazano, że obciążenie tego rodzaju silników, rozpatrywane w dowolnej chwili, może być uważane za zmienną losową wielowymiarową. Zmiany obciążenia silnika w czasie jego pracy uznane zostały za proces obciążeń i przedstawione w formie wielowymiarowego procesu...
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Self diagnostics using smart glasses - preliminary study
Publicationn this preliminary study we analyzed the possibility of the reliable measurement of biomedical signals with some potential hardware extensions of smart glasses. Using specially designed experimental prototypes four category of biomedical signals were measured: electrocardiograms, electromyograms, electroencephalograms and respiration waveforms. Experi- ments with volunteers proved that using even simple construc- tion of sensors...
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Acid–Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis
PublicationUnsymmetrical bisacridines (UAs) represent a novel class of anticancer agents previously synthesized by our group. Our recent studies have demonstrated their high antitumor potential against multiple cancer cell lines and human tumor xenografts in nude mice. At the cellular level, these compounds affected 3D cancer spheroid growth and their cellular uptake was selectively modulated by quantum dots. UAs were shown to undergo metabolic...
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The role of depressive and anxiety symptoms in the evaluation of cardiac rehabilitation efficacy after coronary artery bypass grafting surgery
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Improved-Efficacy EM-Driven Optimization of Antenna Structures Using Adaptive Design Specifications and Variable-Resolution Models
PublicationOptimization-driven parameter tuning is an essential step in the design of antenna systems. Although in many cases it is still conducted through parametric studies, rigorous numerical methods become a necessity if truly optimum designs are sought for, and the problem intricacies (number of variables, multiple goals, constraints) make the interactive approaches insufficient. The two practical considerations of electromagnetic (EM)-driven...
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THE EVALUATION OF EFFICACY OF VALBAZEN (PFLIZER) IN THE TREATMENT OF GASTRO-INTESTINAL TRACT PARASITE INVASIONS IN BEEF CATTLE OF WEST POMERANIA
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A novel in vitro assay for assessing efficacy and toxicity of antifungals using human leukaemic cells infected with Candida albicans
PublicationAims: This study describes a novel in vitro assay that simultaneously determines antifungal efficiency and host cell toxicity using suspensions of human leukaemic cells (HL-60) infected with Candida albicans. Methods and Results: The effect of Candida infection on host cell viability was evaluated by the microscopy of trypan blue-stained cells and lactate dehydrogenase (LDH) activity. The in vitro ‘drug potency assay’ utilized...
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A Comprehensive Review on the Medicinal Importance; Biological and Therapeutic Efficacy of Lagenaria siceraria (Mol.) (Bottle Gourd) Standley Fruit
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Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results
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