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Search results for: BIOLOGICAL SYSTEM MODELING
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Environmental risk assessment of Polish wastewater treatment plant activity
PublicationWastewater treatment plants (WWTPs) play an extremely important role in shaping modern society's environmental wellbeing and awareness, however only well operated and supervised systems can be considered as environmentally sustainable. For this reason, an attempt was undertaken to assess the environmental burden posed by WWTPs in major Polish cities by collecting water samples prior to and just after wastewater release points....
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Phage-Directed Synthesis of Photoluminescent Zinc Oxide Nanoparticles under Benign Conditions
PublicationBiological systems, especially bacteriophages and peptides, are an attractive green alternative to other known methods of nanoparticle synthesis. In this work, for the first time, bacteriophages were employed to synthesize a specific peptide, capable of producing nanoparticles (NPs). Derivatives of M13 bacteriophage exposing a ZnO-binding peptide (TMGA-LGLKWPV) on either pIII or pVIII phage coat protein were constructed and used...
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Biosynthetic and synthetic access to amino sugars.
PublicationAmino sugars are important constituents of a number of biomacromolecules and products of mi crobial secondary metabolism, including antibiotics. For most of them, the amino group is located at the positions C1, C2 or C3 of the hexose or pentose ring. In biological systems, amino sugars are formed due to the catalytic activity of specific aminotransferases or amidotransferases by introducing an amino functionality derived from L-glutamate...
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Plasma-Based Deposition and Processing Techniques for Optical Fiber Sensing
PublicationPlasma-based techniques are widely applied for well-controlled deposition, etching or surface functionalization of a number of materials. It is difficult to imagine fabrication of novel microelectronic and optoelectronic devices without using plasma-enhanced deposition of thin films, their selective etching or functionalization of their surfaces for subsequent selective binding of chemical or biological molecules. Depending on...
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Effects of Different Aeration Modes on Ammonia Removal from Sludge Digester Liquors in the Nitritation-Anammox Process
PublicationSludge digester liquors can be responsible for up to one third of the nitrogen load to the biological step of wastewater treatment plants (WWTPs). The conventional process for ammonia removal via two sequential processes, i.e. nitrification and denitrification, is increasingly being challenged by a one-step process in which ammonium is oxidized directly to nitrogen gas e.g. ammonium oxidation (anammox) process. In this novel process,...
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Endocrine Disrupting Compounds – Problems and Challenges
PublicationIn this chapter, information about some of the estrogenic compounds and their environmental fate and biological influence can be found. Special attention is paid to the review of the analytical approaches used at the stages of detection and determination of Endocrine Disrupting Compounds (EDCs) in the environmental samples. Also, a brief characterization of both cellular and non-cellular bioassays is presented. The discovery of...
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Deep Learning-Based Cellular Nuclei Segmentation Using Transformer Model
PublicationAccurate segmentation of cellular nuclei is imperative for various biological and medical applications, such as cancer diagnosis and drug discovery. Histopathology, a discipline employing microscopic examination of bodily tissues, serves as a cornerstone for cancer diagnosis. Nonetheless, the conventional histopathological diagnosis process is frequently marred by time constraints and potential inaccuracies. Consequently, there...
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Mangiferin: A comprehensive review on its extraction, purification and uses in food systems
PublicationWith the target of fabricating healthier products, food manufacturing companies look for natural-based nutraceuticals that can potentially improve the physicochemical properties of food systems while being nutritive to the consumer and providing additional health benefits (biological activities). In this regard, Mangiferin joins all these requirements as a potential nutraceutical, which is typically contained in Mangifera indica...
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Numerical and quantitative analysis of HIV/AIDS model with modified Atangana-Baleanu in Caputo sense derivative
PublicationFractional calculus plays an important role in the development of control strategies, the study of the dynamical transmission of diseases, and some other real-life problems nowadays. The time-fractional HIV/AIDS model is examined using a novel method in this paper. Based on the Atangana-concept Baleanu’s of a derivative in the Caputo sense, the current modified fractional derivative operator uses singular and non-local kernels....
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Fragmentomic analysis of biopeptides in silico released from milk proteins
PublicationThe fragmentomic-assisted method was employed to predict the biological potential of peptides derived from milk proteins hydrolyzed by papain and bromelain. Firstly, protein sequences were acquired from the BIOPEP-UWM database and then hydrolyzed by the above enzymes using a BIOPEP-UWM tool called “Enzyme(s) action”. The released peptides were defined as parent peptides and further analyzed for the presence of shorter peptidic...
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A mobile loop order–disorder transition modulates the speed of chaperonin cycling
PublicationMolecular machines order and disorder polypeptides as they form and dissolve large intermolecular interfaces, but the biological significance of coupled ordering and binding has been established in few, if any, macromolecular systems. The ordering and binding of GroES co-chaperonin mobile loops accompany an ATP-dependent conformational change in the GroEL chaperonin that promotes client protein folding. Following ATP hydrolysis,...
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Use of Escherichia coli Nissle 1917 producing recombinant colicins for treatment of IBD patients
PublicationPatients with Crohn’s Disease and ulcerative colitis infected with Adherent-Invasive Escherichia coli strains constitute the largest group among Inflammatory Bowel Disease subjects, when taking into account all known etiological agents of the disease. A possible link between these pathogenic bacteria and inflammation process has gained the confidence in recently published papers. Observed enteric neuroglial cells apoptosis and...
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Mesophilic and thermophilic dark fermentation course analysis using sensor matrices and chromatographic techniques
PublicationProduction of biofuels from biomass is expected to benefit the society and the environment. At present, bio waste residues processing includes hydrolysis, dark fermentation, photofermentation, pyrolysis, gasification, and chemical synthesis. As the composition and the chemical structure of organic substances affect the efficiency of mentioned processes, it is believed that the glucose concentration is a crucial parameter for the...
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Colored Tattoo Ink Screening Method with Optical Tissue Phantoms and Raman Spectroscopy
PublicationDue to the increasing popularity of tattoos among the general population, to ensure their safety and quality, there is a need to develop reliable and rapid methods for the analysis of the composition of tattoo inks, both in the ink itself and in already existing tattoos. This paper presents the possibility of using Raman spectroscopy to examine tattoo inks in biological materials. We have developed optical tissue phantoms mimicking...
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Tetrahydroquinolinone derivatives exert antiproliferative effect on lung cancer cells through apoptosis induction
PublicationThe anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new anticancer drugs. In this work, we designed a brief synthetic pathway and obtained a series of novel 8-phenyltetrahydroquinolinone derivatives functionalized with benzyl-type moieties at position...
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Numerical Modeling of Cone Penetration Test in Slightly Overconsolidated Clay with Arbitrary Lagrangian-Eulerian Formulation
PublicationIn this paper the results of the cone penetration test (CPT) modeling with the arbitrary Lagrangian-Eulerian (ALE) formulation provided by Abaqus software package have been presented. The study compares the cone resistance and sleeve friction obtained in numerical analysis with values measured in soundings performed in the uniform layer of clayey soil in the Koszalin area. The clay layer was found to be slightly overconsolidated...
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A Goal-Oriented Error Estimator for Reduced Basis Method Modeling of Microwave Devices
PublicationThis letter proposes a novel a-posteriori error estimator suitable for the reduced order modeling of microwave circuits. Unlike the existing error estimators based on impedance function residuals, the new one exploits the residual error associated with the computation of the scattering matrix. The estimator can be effectively used in the Reduced Basis Method (RBM) to automatically generate reduced-order models. The results of numerical...
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Low-Cost Modeling of Microwave Components by Means of Two-Stage Inverse/Forward Surrogates and Domain Confinement
PublicationFull-wave electromagnetic (EM) analysis is one of the most important tools in the design of modern microwave components and systems. EM simulation permits reliable evaluation of circuits at the presence of cross-coupling effects or substrate anisotropy, as well as for accounting for interactions with the immediate environment. However, repetitive analyses required by EM-driven procedures, such as parametric optimization or statistical...
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Cost-Efficient Surrogate Modeling of High-Frequency Structures Using Nested Kriging with Automated Adjustment of Model Domain Lateral Dimensions
PublicationSurrogate models are becoming popular tools of choice in mitigating issues related to the excessive cost of electromagnetic (EM)-driven design of high-frequency structures. Among available techniques, approximation modeling is by far the most popular due to its versatility. In particular, the surrogates are exclusively based on the sampled simulation data with no need to involve engineering insight or problem-specific knowledge....
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Numerical analysis of chip removing system operation in circular sawing machine using CFD software
PublicationPaper presents the analysis of the results of numerical simulations of the air flow process of wood chips removing system in the circular sawing machine. The attention is focused on the upper cover and bottom shelter of the chip removing system. Within the framework of the work a systematic numerical modeling of the air flow distribution in the cover and shelter during operation of the selected rotational speed of saw blade with...
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Fading Modeling in Maritime Container Terminal Environments
PublicationIn this paper, an analytical model for slow and fast fading effects in maritime container terminals is derived, from fitting distributions to the results of measurements performed in an actual operational environment. The proposed model is composed of a set of equations, enabling to evaluate fading statistical distribution parameters for different system and environments conditions, as a function of frequency, base station antenna...
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Open Data Capability Architecture - An Interpretive Structural Modeling Approach
PublicationDespite of increasing availability of open data as a vital organizational resource, large numbers of startups and organizations fail when it comes to utilizing open data effectively. This shortcoming is attributable to the poor understanding of what types of capabilities are required to successfully conduct data related activities. At the same time, research on open data capabilities and how they relate to one another remains sparse....
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Rapid EM-driven antenna dimension scaling through inverse modeling
PublicationIn this letter, a computationally feasible technique for dimension scaling of antenna structures is introduced. The proposed methodology is based on inverse surrogate modeling where the geometry parameters of the antenna structure of interest are explicitly related to the operating frequency. The surrogate model is identified based on a few antenna designs optimized for selected reference frequencies. For the sake of computational...
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Wireless intelligent audio-video surveillance prototyping system
PublicationThe presented system is based on the Virtex6 FPGA and several supporting devices like a fast DDR3 memory, small HD camera, microphone with A/D converter, WiFi radio communication module, etc. The system is controlled by the Linux operating system. The Linux drivers for devices implemented in the system have been prepared. The system has been successfully verified in a H.264 compression accelerator prototype in which the most demanding...
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Biological effect of hydrothermally synthesized silica nanoparticles within crystalline hydroxyapatite coatings for titanium implants
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Data set generation at novel test-rig for validation of numerical models for modeling granular flows
PublicationSignificant effort has been exerted on developing fast and reliable numerical models for modeling particulate flow; this is challenging owing to the complexity of such flows. To achieve this, reliable and high-quality experimental data are required for model development and validation. This study presents the design of a novel test-rig that allows the visualization and measurement of particle flow patterns during the collision...
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Substrate noise modeling in early floorplanning of MS-SOCs.
PublicationW pracy zaproponowano model częstotliwościowy bloków analogowych wrażliwych na zakłócenia oraz bloków cyfrowych generujących zakłócenia w systemach mieszanych realizowanych na wspólnym podłożu krzemowym. Zaproponowane modele zostały wykorzystane w oprogramowaniu optymalizującym rozmieszczenie bloków funkcjonalnych na struktórze krzemowej. Dzieki użyciu procedur optymalizacyjnych uzyskano znaczącą redukcje poziomu zakłóceń przy...
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Stereo image visualization for a VISROBOT system
PublicationThe article describes a novel approach to robotic vision in mobile robot systems. The system implements a Visrobot system which implements a generic idea of using mobile robots for exploring an indoor environment. The task of such a robot is to visualize a stereo image properly for an operator. The system uses different stereo baseline values. Variable baseline can result in increasing depth resolution for distant objects. We assume...
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Novel hierarchical nonlinear control algorithm to improve dissolved oxygen control in biological WWTP
PublicationWastewater treatment is a problem known to humankind for centuries. The quality of treated sewage determines the condition of reservoirs around the world. Control of such a complex and nonlinear system as a wastewater treatment plant requires thorough knowledge of the process. The paper presents a hierarchical control system of a Sequencing Batch Reactor (SBR) in Wastewater Treatment Plant (WWTP) taking into account a model based...
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The protocol for using elastic wall model in modeling blood flow within human artery
PublicationMedical diagnostic tools will play a major role in the future for an effective patient treatment and reduction their mortality, related to the cardiovascular system diseases (CVDs). There is an urgent need for developing diagnostic procedure to be robust, reliable, accurate and efficient, in the framework of a paradigm shift. Application of numerical techniques is seen as a perspective tool for such purpose. Nevertheless, existing...
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Elimination of clicks from archive speech signals using sparse autoregressive modeling
PublicationThis paper presents a new approach to elimination of impulsivedisturbances from archive speech signals. The proposedsparse autoregressive (SAR) signal representation is given ina factorized form - the model is a cascade of the so-called formantfilter and pitch filter. Such a technique has been widelyused in code-excited linear prediction (CELP) systems, as itguarantees model stability. After detection of noise pulses usinglinear...
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Measurement system based on USB Z-Wave controller
PublicationA wireless measurement system based on the Z-Wave standard is presented in this paper. The system is composed of a U SB Z-Stick Gen5 controller connected to a Personal Computer and a Fibaro controller FGRGBWM-441. Operation of the system is controlled by software written in C++ using OpenZWave library. Some metrological aspects of the system are evaluated: accuracy, linearity, resolution and frequency of voltage measurements.
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Analysis of an Energy Management System of a Small Plant Connected to the Rural Power System
PublicationThis paper presents the analysis of an energy management system (EMS) implemented to fulfill the requirements of a microgrid (MG) power supply owned by a small industrial company and connected to the rural power system. The main goal of this system is to ensure connection with the existing rural power system in terms of energy exchange, as well as to perform islanding mode operation of the microgrid based on the energy demand of...
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Modeling the Effects of Slowly Biodegradable Substrate at Large WWTP in Northern Poland
PublicationThe essential study was divided into two parts: experimental investigation and mathematical modeling using special platform to computer simulations. In the first part of research an innovative measurement procedure for an indirect determination of the effect of biodegradable particulate and colloidal Xs substrate was developed and implemented. The results of laboratory tests were used futher to verify the mechanism of the hydrolysis...
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Influence of Primary Ligands (ODA, TDA) on Physicochemical and Biological Properties of Oxidovanadium (IV) Complexes with Bipy and Phen as Auxiliary Ligands
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Overview of Fading Channel Modeling
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Modeling of the denture’s elastic base
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Shipyard Crane Modeling Methods
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Usability of UML modeling tools
PublicationNarzędzia wspomagające modelowanie w UML pełnią istotną rolę w procesie wytwarzania i utrzymania oprogramowania. Badanie użyteczności tych narzędzi ma na celu poprawę produktywności oraz satysfakcji z ich użytkowania. W referacie zaprezentowano badania użyteczności za pomocą trzech metod: eksperymentalnego testowania efektywności, zapytań o aspekty użyteczności testowanych narzędzi oraz analitycznej metody GOMS (ang. Goals, Operators,...
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Reliable Networks Design and Modeling
PublicationSłowo wstępne numeru specjalnego czasopisma Telecommunication Systems Journal
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Design and modeling of reliable networks
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Modeling Volunteer Based Systems
PublicationThere are two main approaches to processing tasks requiring high amounts of computational power. One approach is using clusters of mostly identical hardware, placed in dedicated locations [1, 2, 3]. The other approach is outsourcing computing resources from large numbers of volunteers connected to the Internet [7]. This chapter presents an application of a mathematical model of the volunteer computing presented in Volume 1 of this...
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Rapid dimension scaling of triple-band antennas by means of inverse surrogate modeling
PublicationGeometry scaling of antennas, i.e., finding optimum dimensions of the structure for given operating conditions and material parameters is an important yet challenging problem. In this paper, we discuss fast dimension scaling of triple-band antennas with respect to operating frequencies. We adopt the inverse surrogate modeling approach where the surrogate model is a function of the three operating frequencies of the antenna and...
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Dynamics of S-unimodal maps used in population modeling.
Open Research DataS-unimodal maps are maps of the interval with negative Schwarzian derivative and having only one turning point (such that the map is increasing to the left of the turning point and decreasing to the right of it). Theory of S-unimodal maps is now a well-developed branch of discrete dynamical systems, including famous Singer theorem which implies existence...
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On Accuracy Modeling of Gas Turbine Cycles by the In-house COM-GAS Code
PublicationIn this paper, a comparison of accuracy modeling of gas turbine cycles between the basic (classical) model and the in-house COM-GAS code has been presented. The basic model uses a semi-perfect gas and well known projecting assumption. On the other hand, the computational flow mechanics (CFM) basis on a real gas by using thermodynamic tables. The thermodynamic analysis of thermal cycles, simply gas cycle GT8C and gas turbine cycle...
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Cost-Efficient Two-Level Modeling of Microwave Passives Using Feature-Based Surrogates and Domain Confinement
PublicationA variety of surrogate modelling techniques has been utilized in high-frequency design over the last two decades. Yet, the curse of dimensionality still poses a serious challenge in setting up re-liable design-ready surrogates of modern microwave components. The difficulty of the model-ing task is only aggravated by nonlinearity of circuit responses. Consequently, constructing a practically usable surrogate model, valid across...
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Greenhouse control system design
PublicationCoraz większa populacja i zmniejszające się tereny uprawne wymusza efektywniejsze metody uprawy roślin. Zaradzić temu mogą układu hydroponiczne, które dzięki rozwojowi techniki są w stanie osiągać znacznie większe oraz bardziej jednorodne plony. Jest to możliwe dzięki zaawansowanym systemom opartym na dokładnych urządzeniach pomiarowych, sterowaniu w zamkniętej pętli oraz mikrokontrolerom umożliwiającym...
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Reduced-cost surrogate modeling of input characteristics and design optimization of dual-band antennas using response features
PublicationIn this article, a procedure for low-cost surrogate modeling of input characteristics of dual-band antennas has been discussed. The number of training data required for construction of an accurate model has been reduced by representing the antenna reflection response to the level of suitably defined feature points. The points are allocated to capture the critical features of the reflection characteristic, such as the frequencies...
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A heterogenous wireless system for maritime communication - the netBaltic system architecture
PublicationIn the article, the concept of a heterogeneous wireless maritime mesh network offering transmission for e.g., e-navigation services is presented. The constrains of existing and competitive solutions are discussed showing the need for a new system. The authors present detailed information about a netBaltic node's architecture and networking mechanisms offering different transmission capabilities and proposed for use on different...
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Decentralized Microgrid Energy Management System with Market-Based Energy Trade System
PublicationThis paper presents a decentralized energy management system for a power microgrid, which integrates individual users, who own renewable energy sources and energy storages. The purpose of the system is to make optimal use of available resources to cover the electricity needs of the whole microgrid. Thanks to the energy exchange system, in addition to exchanges with the distribution network, the system also allows trades within...