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Polymeric Bearings as a new base isolation system suitable for mitigating machine-induced vibrations
PublicationThe present paper summarizes the preliminary results of the experimental shaking table investigation conducted in order to verify the effectiveness of a new base isolation system consisting of Polymeric Bearings in reducing strong horizontal machine-induced vibrations. Polymeric Bearing considered in the present study is a prototype base isolation system, which was constructed with the use of a specially prepared flexible polymer...
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Utilization of Gaseous Carbon Dioxide and Industrial Ca-rich Waste for Calcium Carbonate Precipitation: A Review
PublicationTechnologies for the management of various types of waste and the production of useful products from them are currently widely studied. Both carbon dioxide and calcium-rich waste from various production processes are problematic wastes that can be used to produce calcium carbonate. Therefore, the purpose of this paper is to provide an overview about the state of the development of processes that use these two wastes...
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Shear Cap Size Selection Method Based on Parametric Analysis of ACI-318 Code and Eurocode 2 Standard
PublicationThe scope of the paper is to propose a method for determining the size of shear caps in a slab–column-connections-reinforced concrete structure. Usually, shear heads are used to enhance slab–column connection, especially when the transverse reinforcement does not give the required punching shear load capacity. The dimensions of the shear head should provide the punching shear resistance of the connection inside and outside the...
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Testing of low temperature behaviour of asphalt mixtures in bending creep test
PublicationThe paper presents a method of bending beam test and its importance for evaluation of asphalt mixtures behaviour at low temperatures. Two types of asphalt mixtures: asphalt concrete AC with normal paving grade bitumen and stone mastic asphalt SMA with SBS-modified bitumen were tested. Long-term oven ageing (LTOA) test was also used in the laboratory according to SHRP procedure. The Burgers model was applied and rheological parameters...
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The effect of multiaxial geocomposite reinforcement on fatigue performance and crack propagation delay in double-layered asphalt beams
PublicationThe presented study investigates the effect of a recently developed multiaxial geocomposite made of polypropylene geogrid and non-woven fabric on the delay of crack propagation, based on four-point bending tests of large asphalt concrete beams – both for reinforced and non-reinforced specimens. Several approaches are described in this study, including analysis of stiffness modulus decrease and analysis of crack propagation using...
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DESIGN AND CONSTRUCTION OF TILTED WALLS IN ACCORDANCE WITH CODES' PROVISIONS ON THE EXAMPLE OF THE CONSTRUCTION OF THE MUSEUM OF THE SECOND WORLD WAR IN GDAŃSK
PublicationThe purpose of this article was to introduce the design and construction of tiled walls in accordance to codes' restrictions. The construction of the Museum of the Second World War in Gdańsk was chosen to be an example of its successful use in practice. Theoretical knowledge was based on PN-EN 1992-1-1:2008 and fib Model Code for Concrete Structures 2010. Although codes' recommendations seem curt, practice prove structural advance....
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Synthetic strategies in construction of organic macromolecular carrier–drug conjugates
PublicationMany metabolic inhibitors, considered potential antimicrobial or anticancer drug candidates, exhibit verylimited ability to cross the biological membranes of target cells. The restricted cellular penetration ofthose molecules is often due to their highhydrophilicity. One of the possible solutions to this problem is aconjugation of an inhibitor with a molecular organic nanocarrier. The conjugate thus formed should beable to penetrate...
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Comparative evaluation of different methods for determining phytochemicals and antioxidant activity in products containing betalains - Verification of beetroot samples
PublicationThis study presents methods that can be used to assess the health quality of products containing betalains. The paper compares and verifies data on the phytochemical composition of three different pigmented beetroot cultivars using spectrophotometric, HPLC-DAD, HPTLC and LC-Q-Orbitrap-HRMS techniques. Additionally, we compared the total antioxidant activity in both the cell-free and cellular systems. Betalain contribution to antioxidant...
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Polydopamine Biomaterials for Skin Regeneration
PublicationDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
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Antimicrobial molecular nanocarrier–drug conjugates
PublicationMany antimicrobial drugs are poorly active against pathogenic microbes causing intracellular infections, such as Mycobacterium tuberculosis or Plasmodium falciparum. On the other hand, several known antimicrobial agents are not effective enough because of their limited cellular penetration. A common feature of both challenges is the inability of an active agent to cross the biological membrane(s). One of the possible approaches...
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Przepustowość przepustu niezatopionego
PublicationPodczas przepływu w warunkach niezatopionego wlotu i wylotu w przewodzie przepustu woda tworzyć będzie swobodne zwierciadło. Przepływ bezciśnieniowy w przewodzie przepustu może wystąpić również w warunkach zatopionego wlotu. W pracy porównano wyniki obliczeń przepustowości całego przepustu i samego przewodu o przekroju kołowym i kwadratowym. W warunkach spokojnego ruchu wody, przy braku spiętrzenia na wylocie, o przepustowości...
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A Survey of Fast-Recovery Mechanisms in Packet-Switched Networks
PublicationIn order to meet their stringent dependability requirements, most modern packet-switched communication networks support fast-recovery mechanisms in the data plane. While reactions to failures in the data plane can be significantly faster compared to control plane mechanisms, implementing fast recovery in the data plane is challenging, and has recently received much attention in the literature. This survey presents a systematic,...
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Numerical Study on Seismic Response of a High-Rise RC Irregular Residential Building Considering Soil-Structure Interaction
PublicationThe objective of the present study is to investigate the importance of soilstructure interaction effects on the seismic response of a high-rise irregular reinforced-concrete residential building. In order to conduct this research, a detailed three-dimensional structure model was subjected to various earthquake excitations, also including a strong mining tremor. Soil-foundation flexibility was represented using the spring-based...
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Method of determining the degree of liquid aeration in a variable capacity displacement pump
PublicationThe Author concludes, that there is a possibility of determining a concrete value of the liquid aeration coefficient during the pump operation by finding such value of coefficient with which the increase of torque of mechanical losses is proportional to the indicated torque determined with a fixed value of increase of pressure in the pump working chambers. The fixed value of increase of pressure assumed in searching the liquid...
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Recommendations for Urban Freight Policy Development in Gdynia
PublicationThe purpose of this paper was to provide practical recommendations on how to develop Gdynia’s urban freight policy based on actual planning experience and characteristics of potential measures. Freight policy scheme was developed as a result of three interrelated factors: a) the general procedure of the urban freight planning, b) the city's current planning stage analysis and, c) characteristics of urban freight objectives and...
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Optimized Computational Intelligence Model for Estimating the Flexural Behavior of Composite Shear Walls
PublicationThis article presents a novel approach to estimate the flexural capacity of reinforced concrete-filled composite plate shear walls using an optimized computational intelligence model. The proposed model was developed and validated based on 47 laboratory data points and the Transit Search (TS) optimization algorithm. Using 80% of the experimental dataset, the optimized model was selected by determining the unknown coefficients of...
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Projektowanie budynków użyteczności publicznej narażonych na ataki terrorystyczne z wykorzystaniem systemu ochrony pasywnej
PublicationW artykule przedstawiono projektowanie systemów ochrony pasywnej w budynkach użyteczności publicznej, które mogą posłużyć jako przykład i stanowić podstawę do dalszych założeń przy projektowaniu budynków narażonych na obciążenie wybuchem spowodowanym przez ataki terrorystyczne. W pracy przeprowadzono symulacje numeryczne na przykładzie ściany budynku użyteczności publicznej wykonanego w technologii żelbetowej. Obliczenia wykonano...
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Models of Structures in Didactics
PublicationThe final aim of teaching students subjects, such as structural mechanics, reinforced concrete, and steel structures is to teach them how structures work in a given building as well as to provide them with skills enabling them to calculate and design structures. The behavioral model of the structure, contrary to the architectural model, which focuses mainly on the external form of the building, shows workings from both the static...
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Photogrammetric and total station's measurement of compressed column's model
PublicationModelling studies continue to play an important role. One of such study is stress determination in the reinforcement bars of reinforced columns and determine column's axis deformation. The article presents measurements results of control points located on the model of reinforced concrete column. The column was compressed in few series till it's destruction. In this studies, photogrammetric method and total station measurements...
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The Caucasian flora: a still-to-be-discovered rich source of antioxidants
PublicationCellular redox homeostasis is a state of balance between the formation of Usually Reactive Oxygen and / or Nitrogen Species (ROS/RNS), endogenous antioxidant defence systems, and exogenous dietary antioxidants. The disturbance of redox homeostasis, by the overproduction of endogenous ROS/RNS, may increase the risk of development of so-called civilisation diseases. The solution seems to be either the increased production of endogenous...
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The Influence of Substitution of a Phosphorus-Containing Polyol with the Bio-polyol on the Properties of Bio-based PUR/PIR Foams
PublicationIn this work, effects of incorporating of a phosphorus-containing polyol into rigid polyurethane/polyisocyanurate foams’ formulations developed with use of two different bio-based polyols, derived from crude glycerol or liquefied cellulose were examined. The bio-polyol derived from crude glycerol was synthesized via two-step process from crude glycerol and castor oil, whereas the bio-polyol derived from liquefied cellulose was...
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Oxylipin profiling for clinical research: Current status and future perspectives
PublicationOxylipins are potent lipid mediators with increasing interest in clinical research. They are usually measured in systemic circulation and can provide a wealth of information regarding key biological processes such as inflammation, vascular tone, or blood coagulation. Although procedures still require harmonization to generate comparable oxylipin datasets, performing comprehensive profiling of circulating oxylipins in large studies...
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Study on Speech Transmission under Varying QoS Parameters in a OFDM Communication System
PublicationAlthough there has been an outbreak of multiple multimedia platforms worldwide, speech communication is still the most essential and important type of service. With the spoken word we can exchange ideas, provide descriptive information, as well as aid to another person. As the amount of available bandwidth continues to shrink, researchers focus on novel types of transmission, based most often on multi-valued modulations, multiple...
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Study on CPU and RAM Resource Consumption of Mobile Devices using Streaming Services
PublicationStreaming multimedia services have become very popular in recent years, due to the development of wireless networks. With the growing number of mobile devices worldwide, service providers offer dedicated applications that allow to deliver on-demand audio and video content anytime and everywhere. The aim of this study was to compare different streaming services and investigate their impact on the CPU and RAM resources, with respect...
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EVALUATION OF THE USE OF M2M-TYPE NB-IoT AND LTE TECHNOLOGIES FOR MARITIME COMMUNICATION SYSTEMS
PublicationThe development of IoT (the Internet of Things) wireless transmission opens a new era in communication systems. In the next years, the development and implementation of IoT systems will be very dynamic. It can be seen that the solutions of LTE – NB-IoT (Long Term Evolution – Narrowband IoT) transmission devices are implemented in a wide range of terrestrial solutions, e.g. smart grids. This paper aims to analyse the possibility...
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Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations
PublicationIncreasing evidence indicates a role of hyperpolarization activated cation (HCN) channels in controlling the resting membrane potential, pacemaker activity, memory formation, sleep, and arousal. Their disfunction may be associated with the development of epilepsy and age-related memory decline. Neuronal hyperexcitability involved in epileptogenesis and EEG desynchronization occur in the course of dementia in human Alzheimer’s Disease...
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Circularly Polarized Metalens Antenna Design for 5G NR Sub-6 GHz Communication Systems
Publication5G NR (new radio) FR1 range refers to as Sub-6GHz band (410MHz to 7125MHz and 3.4GHz to 6GHz). In this paper, the frequency range of interest is from 3.4 to 6GHz, as many cellular companies are focusing on this Sub-6GHz band. A wideband circularly polarized (CP) antenna radiator is designed with diamond shape patches, fed by a microstrip line at the bottom through a rectangular shape wide slot on a ground plane. The proposed CP...
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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublicationColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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New First - Path Detector for LTE Positioning Reference Signals
PublicationIn today's world, where positioning applications reached a huge popularity and became virtually ubiquitous, there is a strong need for determining a device location as accurately as possible. A particularly important role in positioning play cellular networks, such as Long Term Evolution (LTE). In the LTE Observed Time Difference of Arrival (OTDOA) positioning method, precision of device location estimation depends on accuracy...
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Therapeutic intervention by the simultaneous inhibition of DNA repair and type I or type II DNA topoisomerases: one strategy, many outcomes
PublicationMany anticancer drugs reduce the integrity of DNA, forming strand breaks. This can cause mutations and cancer or cell death if the lesions are not repaired. Interestingly, DNA repair-deficient cancer cells (e.g., those with BRCA1/2 mutations) have been shown to exhibit increased sensitivity to chemotherapy. Based on this observation, a new therapeutic approach termed 'synthetic lethality' has been developed, in which radiation...
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Wpływ zbrojenia polimerowymi włóknami rozproszonymi na wybrane właściwości mieszanek mineralno-asfaltowych
PublicationW artykule przedstawiono wybrane wyniki badań mieszanek mineralno-asfaltowych zbrojonych polimerowymi włóknami rozproszonymi. Ocenie poddano mieszankę włókien zbrojących aramidowo-poliolifenowych pod kątem wpływu ich zastosowania na właściwości niskotemperaturowe i odporności na deformacje trwałe mieszanek mineralno-asfaltowych. Właściwości niskotemperaturowe oceniano na podstawie testu zginania próbek belkowych oraz na podstawie...
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Direct design of Controlled Modulus Columns (CMC) based on in-situ testing
PublicationIn this paper, the serviceability limit state and bearing capacity of tension screw displacement piles were analyzed using the results of static pile load tests, carried out on the test plot near the Elbląg city, and field, and laboratory tests. The paper presents the methodology of determining the pile load-settlement curve using different types of t-z transfer functions. The new method of constructing the pile load-settlement...
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New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives
PublicationIn the present work, we report a new class of potent steroid sulphatase (STS) inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives. Within the set of new STS inhibitors, 6-(1-(1,2,3-trifluorophenyl)-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate 3L demonstrated the highest activity in the enzymatic assay inhibiting the STS activity to 7.98% at 0.5 µM concentration. Furthermore, to verify...
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Labellum and gynostemium micromorphology in Polystachya (Orchidaceae)
PublicationPolystachya is a large, pantropical orchid genus of 200 species, most of which occur as epiphytes in sub-saharan Africa. The three-lobed labellum of most Polystachya species possesses a fleshy callus and various types of trichomes and papillae. In this paper, we present the results of micromorphological studies on the labellum of 20 species, representing eight of the 13 sections in the genus, using scanning electron microscopy...
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Gelatin and gelatin/starch-based films modified with sorbitol for wound healing
PublicationGelatin-based films modified with sorbitol were produced from gelatin solution or gelatin/starch blends using a simple and low-cost solvent casting method, and subsequently, their physicochemical, mechanical, and biocompatibility properties were characterized. This work focused on developing and optimizing a biopolymeric blend to improve the pure biopolymers’ properties for potential biomedical applications such as wound dressing....
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Marine polymers in tissue bioprinting: Current achievements and challenges
PublicationBioprinting has a critical role in tissue engineering, allowing the creation of sophisticated cellular scaffolds with high resolution, shape fidelity, and cell viability. Achieving these parameters remains a challenge, necessitating bioinks that are biocompatible, printable, and biodegradable. This review highlights the potential of marine-derived polymers and crosslinking techniques including mammalian collagen and gelatin along...
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The Impact of Hybrid Flame Retardant Compositions on the Performance of Foamed Flexible Polyurethane/Ground Tire Rubber Composites
PublicationCurrent sustainability-oriented trends affect polyurethane (PU) materials and stimulate the incorporation of recycled or waste-based materials as fillers. Ground tire rubber (GTR) poses as an auspicious candidate due to the excellent performance of car tires. Despite the benefits related to the mechanical performance, it contributes to the increasing flammability of the resulting composites. Herein, presented work assessed the...
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The impact of interactions between polyphenolic antioxidants on the redox-related chemical and biological properties of their mixtures – the extension of food synergy concept.
PublicationThe results of studies indicate that chemopreventive efficiency of isolated phytochemicals is lower than that of polyphenol-rich foods. This discrepancy has been ascribed to the food synergy concept that assumes additive or even synergistic influence of different food ingredients on human health. The results presented in the dissertation made it possible to propose an alternative and innovative explanation of these observations. The...
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A HISTORICAL BUILDING'S RESTORATION IN THE CONSTRUCTIONAL ASPECT ON THE EXAMPLE OF A BUILDING LOCATED IN POLAND
PublicationObjects of cultural heritage are an extremely important element in the proper functioning of the social life. They provide information on our ancestors' actions, as well as shape our culture and social awareness. It is important for the historical objects to provide those information accurately, that is without any unnecessary human intervention over the years of the monument's existence. However, it is not always possible due...
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Influence of the Shear Cap Size and Stiffness on the Distribution of Shear Forces in Flat Slabs
PublicationThe scope of this paper is to investigate analytically and numerically the influence of shear cap size and stiffness on the distribution of shear forces in flat slabs in a slab–column-connections-reinforced concrete structure. The effect of support (shear cap) stiffness on the calculation of the length of the shear control perimeter according to the available methods is presented. Based on the analysis, the authors indicate in...
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Wave Method for Structural Health Monitoring: Testing Using Full-Scale Shake Table Experiment Data
PublicationAn algorithm of the wave method for structural health monitoring (SHM) is tested and calibrated using shake table experiment data of a full-scale, seven-story, reinforced-concrete building slice. The method is based on monitoring changes in the velocity of waves propagating vertically through the structure, identified by least-squares (LSQ) fit of beam models. The experiment was conducted by a team from the University of California,...
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The use of fibre-reinforced polymers (FRP) in bridges as a favourable solution for the environment
PublicationThe purpose of this article is to show the modern engineering, in which sustainability and taking care of ecology play a significant role. The authors are focused on FRP composite materials and their applications in civil engineering. Case studies showing renovation and design of new bridges with the use of FRP are presented and discussed to clarify benefits, which this solution provides. Main advantages of FRP materials in comparison...
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On the Consumption of Multimedia Content Using Mobile Devices: a Year to Year User Case Study
PublicationIn the early days, consumption of multimedia content related with audio signals was only possible in a stationary manner. The music player was located at home, with a necessary physical drive. An alternative way for an individual was to attend a live performance at a concert hall or host a private concert at home. To sum up, audio-visual effects were only reserved for a narrow group of recipients. Today, thanks to portable players,...
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Antitumor 1-nitroacridine derivative C-1748 induces significant apoptosis in pancreatic cancer cells.
PublicationPancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer in the industrial countries. The poor prognosis of pancreatic cancer results from its tendency for late presentation, aggressive invasion, early metastasis, and resistance to chemotherapy. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine...
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EXPERIMENTAL STUDY OF A TEMPORARY STEEL GRANDSTAND UNDER CROWD LOAD
PublicationTemporary structures, such as grandstands, are commonly used during different types of mass events, especially sport and music concerts. In this paper, the results of the experimental study on temporary steel grandstand are presented. The aim of the investigation was to determine modal characteristics of such structures. Modes of free vibrations and corresponding natural frequencies have been obtained for empty and occupied grandstand....
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Phytochemical composition and biological activities of differently pigmented cabbage (Brassica oleracea var. capitata) and cauliflower (Brassica oleracea var. botrytis) varieties
PublicationBACKGROUND:Brassica plants contain awide spectrumofbioactive components that are responsible for their health-promoting potential such as vitamins, polyphenols and glucosinolates. This study attempted to relate the composition of bioactive phytochemicals and chosen biological activities (antioxidant, cytotoxic, anti-genotoxic, and influence on enzymatic activities) for extracts from differently pigmented cabbage (white and red)...
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Effect of selective laser treatment on initiation of fatigue crack in the main part of an undercarriage drag strut
PublicationThis paper presents the results of material characterization and a fatigue test conducted for a laser-re-melted drag strut used in an aircraft landing gear. The drag strut was re-melted with a CO2 laser beam. Eight re-melted paths were made in the form of spiral lines along the axis of the drag strut. Next, the drag strut was subjected to variable loads on a testing machine simulating loads occurring when an aircraft lands. The...
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Novel fused pyran derivatives induce apoptosis and target cell cycle progression in anticancer efficacy against multiple cell lines.
PublicationNitrogen-based heterocycles such as pyrazole, imidazole, 1,2,4-triazole, benzimidazole, and benzotriazole substituted fused pyran derivatives (6a–e, 8a–e, 10a–e, 12a–e,&14a–e) have been synthesized and tested for their in vitro anticancer efficacies against MCF7, A549, and HCT116 cancer cell lines. Among the compounds, 6e, 14b, and 8c were identified as the most potent against MCF7, A549, and HCT116, with IC50 values of 12.46 2.72...
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Small regulatory bacterial RNAs regulating the envelope stress response
PublicationMost bacteria encode a large repertoire of RNA-based regulatory mechanisms. Recent discoveries have revealed that the expression of many genes is controlled by a plethora of base-pairing noncoding small regulatory RNAs (sRNAs), regulatory RNA-binding proteins and RNA-degrading enzymes. Some of these RNA-based regulated processes respond to stress conditions and are involved in the maintenance of cellular homeostasis. They achieve...
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Influence of Selected Warm Mix Asphalt Additives on Cracking Susceptibility of Asphalt Mixtures
PublicationWarm mix asphalt (WMA) has been widely accepted as a future asphalt paving technology. Besides clear advantages, there are still some concerns regarding durability and long-term performance of pavements made with this type of asphalt mixtures. One of the most important issues is low temperature behaviour of WMA because certain additives used for temperature reduction can aect bitumen properties. This paper presents the evaluation...