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Search results for: NATURAL PIGMENTS
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DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
PublicationThe human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylated region (DMR) encompassing HLA-DRB1 exon 2 is particularly affected and displays methylation-sensitive regulatory properties in vitro. Causal inference and Mendelian randomization...
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N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
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Assessment of Emotional Expressions after Full-Face Transplantation
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Operation of a free-electron laser from the extreme ultraviolet to the water window
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Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity
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Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants
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Quantum mechanical which-way experiment with an internal degree of freedom
PublicationFor a particle travelling through an interferometer, the trade-off between the available which-way information and the interference visibility provides a lucid manifestation of the quantum mechanical wave-particle duality. Here we analyse this relation for a particle possessing an internal degree of freedom such as spin. We quantify the trade-off with a general inequality that paints an unexpectedly intricate picture of wave-particle...
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Representing and describing nanomaterials in predictive nanoinformatics
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An ancestral molecular response to nanomaterial particulates
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Superconductivity in CuxTiSe2
PublicationOdkryty został nowy związek nadprzewodzący o wzorze chemicznym CuxTiSe2. Jest to pierwszy znany przypadek związku z występującym CDW (fale gęstości ładunku), gdzie w wyniku domieszkowania chemicznego wzbudzany jest stan nadprzewodnictwa. Dyskutowany jest diagram fazowy dla całego zakresu domieszkowania miedzi: 0 < x < 0.10.
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Realistic noise-tolerant randomness amplification using finite number of devices
PublicationRandomness is a fundamental concept, with implications from security of modern data systems, to fundamental laws of nature and even the philosophy of science. Randomness is called certified if it describes events that cannot be pre-determined by an external adversary. It is known that weak certified randomness can be amplified to nearly ideal randomness using quantum-mechanical systems. However, so far, it was unclear whether randomness amplification...
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Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9
PublicationAt the core of the CRISPR–Cas9 genome-editing technology, the endonuclease Cas9 introduces site-specific breaks in DNA. However, precise mechanistic information to ameliorate Cas9 function is still missing. Here, multimicrosecond molecular dynamics, free energy and multiscale simulations are combined with solution NMR and DNA cleavage experiments to resolve the catalytic mechanism of target DNA cleavage. We show that the conformation...
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Steering is an essential feature of non-locality in quantum theory
PublicationA physical theory is called non-local when observers can produce instantaneous effects over distant systems. Non-local theories rely on two fundamental effects: local uncertainty relations and steering of physical states at a distance. In quantum mechanics, the former one dominates the other in a well-known class of non-local games known as XOR games. In particular, optimal quantum strategies for XOR games are completely determined...
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A large family of filled skutterudites stabilized by electron count
PublicationThe Zintl concept is important in solid-state chemistry to explain how some compounds that combine electropositive and main group elements can be stable at formulas that at their simplest level do not make any sense. The electronegative elements in such compounds form a polyatomic electron-accepting molecule inside the solid, a ‘polyanion’, that fills its available energy states with electrons from the electropositive elements...
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Generic emergence of classical features in quantum Darwinism
PublicationQuantum Darwinism posits that only specific information about a quantum system that is redundantly proliferated to many parts of its environment becomes accessible and objective, leading to the emergence of classical reality. However, it is not clear under what conditions this mechanism holds true. Here we prove that the emergence of classical features along the lines of quantum Darwinism is a general feature of any quantum dynamics:...
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Widespread theta synchrony and high-frequency desynchronization underlies enhanced cognition
PublicationThe idea that synchronous neural activity underlies cognition has driven an extensive body of research in human and animal neuroscience. Yet, insufficient data on intracranial electrical connectivity has precluded a direct test of this hypothesis in a whole-brain setting. Through the lens of memory encoding and retrieval processes, we construct whole-brain connectivity maps of fast gamma (30-100 Hz) and slow theta (3-8 Hz) spectral...
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INFOGEST static in vitro simulation of gastrointestinal food digestion
PublicationDeveloping a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract. These simulations have used a wide range of different conditions that often have very little physiological relevance, and this impedes the meaningful comparison of results. The standardized protocol presented here is based on an international consensus...
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The Hopf theorem for gradient local vector fields on manifolds
PublicationWe prove the Hopf theorem for gradient local vector fields on manifolds, i.e., we show that there is a natural bijection between the set of gradient otopy classes of gradient local vector fields and the integers if the manifold is connected Riemannian without boundary.
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Environmental Degradation of Ramie Fibre Reinforced Biocomposites
PublicationThe degradation process of two kinds of biocomposites, Ramie fibre/Ecoflex R/E and ramie fibre/cellulose nanofibre reinforced corn starch resin R/CS, were studied. It was demonstrated that R/CS degraded faster in natural environments.
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Minimal parameter implicit solvent model for ab initioelectronic-structure calculations
PublicationAbstract - We present an implicit solvent model for ab initio electronic-structure calculations which is fully self-consistent and is based on direct solution of the nonhomogeneous Poisson equation. The solute cavity is naturally defined in terms of an isosurface of the electronic density according to the formula of Fattebert and Gygi (J. Comput. Chem., 23 (2002) 662). While this model depends on only two parameters, we demonstrate...
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Numerical analysis of a temporary steel grandstand
PublicationThe purpose of this paper is to present the results of the numerical analysis focused on the response of the temporary steel scaffolding grandstand subjected to human-induced vibrations due to jumping. Shell as well as beam elements have been used in the numerical model. Its first stage has involved conducting modal analysis in order to determine the modes of free vibrations and the corresponding natural frequencies for the empty...
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Modeling of Ice Phenomena in the Mouth of the Vistula River
PublicationThe mouth of the Vistula River, which is a river outlet located in tideless area, is analyzed. The Vistula River mouth is a man-made, artificial channel which was built in the 19th century in order to prevent the formation of ice jams in the natural river delta. Since the artificial river outlet was constructed, no severe ice-related flood risk situations have ever occurred. However, periodic ice-related phenomena still have an impact...
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Experimental dynamic study on a timber-frame house using shaking table
PublicationThe aim of this paper is to show the results of the shaking table experimental study concerning the behaviour of the model of the timber-frame house under earthquake excitation and impact loading. In order to determine the basic dynamic properties of the undamaged structure, the free vibration and the sweep-sine tests were first conducted. Then, the model was excited using the time history record of the El Centro earthquake of...
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Impact of Volcanic Eruptions on the Occurrence of PAHs Compounds in the Aquatic Ecosystem of the Southern Part of West Spitsbergen (Hornsund Fjord, Svalbard)
PublicationThe paper presents changes in concentration levels of dioxin-like compounds that can be observed over the course of four study seasons in water samples collected from the Arctic watershed of Svalbard. The conducted analysis involved anthropogenic and natural factors that may affect the concentration of PAHs in the study samples of water. An attempt is made to indicate the emission source of the compounds being deposited and to...
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THE IMPACT OF GROUND TIRE RUBBER TREATMENT ON THE THERMAL CONDUCTIVITY OF FLEXIBLE POLYURETHANE/GROUND TIRE RUBBER COMPOSITES
PublicationWaste car tires are burdensome waste, and their utilization is crucial for the natural environment. In many countries, the primary method of their recycling is energy recovery, performed by simple combustion. However, material recycling is much more effective and significantly more beneficial for the natural environment. It results in the generation of ground tire rubber, which can be used to produce polymerrubber composites. It...
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Chemical structure, thermal and mechanical characterization of bio-based polyurethane composites filled with microcrystalline cellulose
PublicationOver the past several decades, the interest in replacing the synthetic components used in the production of polymers and composites with their natural counteparts has been growing. Biocomposites belong to the group of materials produced with the use of renewable raw materials. There has been a recent surge of interest in the industrial applications of composites containing natural fibres reinforced with biopolymers. Biopolymers...
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Semantic OLAP with FluentEditor and Ontorion Semantic Excel Toolchain
PublicationSemantic technologies appear as a step on the way to creating systems capable of representing the physical world as real time computational processes. In this context, the paper presents a toolchain for an ontology based knowledge management system. It consists of the ontology editor, FluentEditor and the distributed knowledge representation system, Ontorion. FluentEditor is a comprehensive tool for editing and manipulating complex...
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Modyfikacja kompozytów elastomerowych NR za pomocą ligniny i glicerolizatu
PublicationPrzedmiotem opisanych w niniejszym artykule badań są wulkanizaty kauczuku naturalnego. Celem pracy było zbadanie wpływu ligniny oraz glicerolizatu na wybrane właściwości kompozytów zawierających kauczuk naturalny. Strukturę chemiczną przygotowanych materiałów potwierdzono, wykorzystując analizę spektroskopową w podczerwieni (FTIR). Zbadano również właściwości mechaniczne przy statycznym rozciąganiu, twardość, ścieralność oraz odbojność...
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A new library for construction of automata
PublicationWe present a new library of functions that construct minimal, acyclic, deterministic, finite-state automata in the same format as the author's fsa package, and also accepted by the author's fadd library of functions that use finite-state automata as dictionaries in natural language processing.
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Mushroom Toxins
PublicationToxins and Other Harmful Compounds in Foods provides information on the contents, distribution, chemical properties, and biological activity of toxins and other harmful compounds in foods that are natural components of the raw materials, accumulated due to microbial actions and environmental pollution, or are generated due to processing.
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University Students’ Research on Artificial Intelligence and Knowledge Management. A Review and Report of Multi-case Studies
PublicationLeading technologies are very attractive for students preparing their theses as the completion of their studies. Such an orientation of students connected with professional experiences seems to be a crucial motivator in the research in the management and business areas where these technologies condition the development of professional activities. The goal of the paper is the analysis of students’ thesis topics defended in the last...
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Diagnosis of Damage in a Steel Tank with Self-Supported Roof through Numerical Analysis
PublicationThe safety of civil engineering structures is one of the most important issues of building industry. That is why the assessment of the damage-involved structural response has recently become of major concern to engineers. Among a number of different approaches to diagnosis of damage, the method of measuring the changes in natural frequencies is considered to be one of the most effective indicators of global damage. From the practical...
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The Concept of Construction of Hybrid Constructed Wetland for Wastewater Treatment in Roztocze National Park
PublicationRoztocze National Park (RNP) is one of 23 national parks in Poland. It was created in 1974 both to protect the natural and cultural heritage as well as to share the park area for science, education and tourism. In caring for the environment, the park removed asbestos coverage, performs thermo-modernization using renewable energy sources by the installation of solar panels and photovoltaic cells on the roofs of buildings, and pellet...
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Analysing the impact of traffic incidents on express road traffic flow using FREEVAL
PublicationTraffic incidents occurring on motorways or express roads cause disruptions and deteriorate traffic conditions. The impact will differ depending on the type of incident, its duration and space blocked on the roadway and can be measured with e.g. average speed reduction, extension of travel time, time lost or overall costs of traffic disruptions. The aim of the paper is to analyse this impact, based on data from the Tri-City Ring...
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Green and sustainable hydrogels based on quaternized chitosan to enhance wound healing
PublicationHydrogel-based biomaterials applied as wound dressings provide the wound with a moist environment, which facilitates tissue regeneration through granulation and re-epithelialization. The inherent flexibility and adjustable architecture of hydrogels enables incorporation of cells, antimicrobial drugs, growth factors, and bioactive compounds, which leads to expediting wound contraction and enhancing the regeneration process. The...
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Evaluation of a company’s image on social media using the Net Sentiment Rate
PublicationVast amounts of new types of data are constantly being created as a result of dynamic digitization in all areas of our lives. One of the most important and valuable categories for business is data from social networks such as Facebook. Feedback resulting from the sharing of thoughts and emotions, expressed in comments on various products and services, is becoming the key factor on which modern business is based. This feedback is...
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Getting to know the potential of social media in forest education
PublicationThe development of social network sites not only facilitates the acquisition and deepening of knowledge but also provides the possibility of easily contacting foresters, specialists in natural sciences and nature enthusiasts. In addition, for some years...
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Rhodotorulic Acid and its Derivatives: Synthesis, Properties, and Applications
PublicationSiderophores are low molecular weight compounds produced by microorganisms to scavenge iron in iron-deficient environments. Rhodotorulic acid, a natural hydroxamate siderophore, plays a vital role in iron acquisition for fungi and bacteria. As the simplest natural hydroxamate siderophore, it exhibits a high affinity for ferric ions, enabling it to form stable complexes that facilitate iron uptake and transport within microorganisms....
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A proposition for integrating elements of game universe by means of behavioral trees
PublicationModern computer games often involve autonomous beings collaborating and competing with each other to reach their objectives in the game universe. It seems only natural to use agent-oriented approach in such cases. This article identifies the rules of building a game universe as an environment for executing agents. The paper also covers a method for decomposing compound behaviors into behavioral trees. Dividing complex behaviors...
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Integration of brood units in game universe
PublicationAn access to a great number of various services allows for decomposition of complex problems Developing a game universe usually involves creation of various units which can be encountered by a player. Those can be lonely or organized in broods animals and monsters wandering around the game world. In order to provide natural gaming experience those units should behave variously depending on the world situation. Those behaviours...
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The role of analytical chemistry in the study of the Anthropocene
PublicationThe term “Anthropocene” refers to not yet formalized epoch of geologic time during which geologic processes have been dominated by the human impact. This impact takes on many forms. Biological, physical and chemical changes to the Earth System caused by anthropogenic activity are recorded in natural archives either as new fossil assemblages (neobiota), anthropogenic deposits or a wide variety of pollutants emitted to the environment....
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Bee Products and Essential Oils as Alternative Agents for Treatment of Infections Caused by S. aureus
PublicationBacteria of the genus Staphylococcus are important human and veterinary pathogens. A crucial characteristic for this group of bacteria is that they can easily acquire mechanisms of antibiotic resistance for a plethora of antibiotics currently in use for human and animal therapies. Therefore, there is a great need to find novel, non-antibiotic chemotherapeutics with marked antistaphylococcal activity. Promising but still underestimated...
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Electrochemical investigations of conductive coatings applied as anodes in cathodic protection of reinforced concrete.
PublicationW pracy przedstawiono rezultaty badań elektrochemicznych polimerów przewodzących z pigmentem grafitowym. Wyznaczono parametry elektrochemiczne badanych powłok w trakcie długotrwałej polaryzacji zbrojonego betonu. W oparciu o pomiary impedancyjne wyznaczono parametry elektrochemiczne powłok przewodzących. Wykazano, że badane powłoki mogą być stosowane w ochronie katodowej żelbetu. Badania wykazały, że optymalne stężenie grafitu...
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Book Review: Vishwas Satgar (ed.), The Solidarity Economy Alternative: Emerging Theory and PracticeSatgarVishwas (ed.), The Solidarity Economy Alternative: Emerging Theory and Practice, University of KwaZulu-Natal Press: Durban, 2014; 332 pp.: ISBN 9781869142575, US$34.44
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Freelance technical writing application for a job which I did not get.
PublicationIn this essay I am going to explore the different ways in which developments in engineering technology and materials science have improved the quality of learning and at the same time somewhat diminished students innate intellectual ability which came as the result of what we know as A.I. According to wikipedia.org the word "education" comes from the conjunction of a Latin words "I lead" or "duco" meaning "I...
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Ochronić ląd.
PublicationArtykuł poświęcony jest metodom ochrony brzegów morskich. W pierwszej jego części omówiono przyczyny powodujące, że prawie 80% polskiego brzegu cofa się, przy czym tempo cofania się stopniowo rośnie. Opisano zalety i wady stosowanych w świecie metod ochrony brzegów wraz z uwzględnieniem współczesnych zaleceń projektowania ochrony brzegu, tj. możliwie jak najmniejszej ingerencji w środowisko naturalne. Na koniec w pracy pokazano,...
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Zmiany konstrukcyjne i technologiczne w budowie instalacji chłodniczych w kontekście zastępowania „F-gazów” oraz ich mieszanin nowymi substancjami o niskim potencjale tworzenia efektu cieplarnianego i substancjami naturalnymi
PublicationZe względu na zmieniające się prawodawstwo UE dotyczące możliwości wykorzystywania czynników należących do grupy tzw. „F-gazów”, pojawiają się liczne nowe problemy i zmiany w konstrukcji oraz eksploatacji urządzeń, wykorzystywanych w szeroko pojętej technice chłodniczej i klimatyzacyjnej. Zmiany te wynikają przede wszystkim z konieczności użytkowania substancji odznaczających się niskim wpływem na środowisko naturalne (ODP=0 i...
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Estimation of groundwater recharge in a shallow sandy aquifer using unsaturated zone modeling and water table fluctuation method
PublicationQuantification of groundwater recharge is one of the most important issues in hydrogeology, especially in view of the ongoing changes in climate and land use. In this study, we use numerical models of 1D vertical flow in the vadose zone and the water table fluctuation (WTF) analysis to investigate local-scale recharge of a shallow sandy aquifer in the Brda outwash plain in northern Poland. We show that these two methods can be...
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A New Approach to Assess Quality of Motion in Functional Task of Upper Limb in Duchenne Muscular Dystrophy
Publication(1) Background: This study presents a new method for the motion quantitative analysis of Duchenne muscular dystrophy patients (DMD) performing functional tasks in clinical conditions. (2) Methods: An experimental study was designed to define how different levels of external mass (light and heavy) influence the performance of the upper limbs of a tested DMD and reference subject (RS) during horizontal movements (level of the waist)...
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Architecture in the field of art on the example of author’s realizations
PublicationThe aim of the article was to show the place of architecture in the space of art on the example of original projects. In the author's opinion, architecture, using an artistic object as a means of expression, influences the process of living by showing the recipient, who is an inhabitant, important values from the point of view of creating a house that ensures a good quality of life and strengthening the understanding of both various...