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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
PublicationPsoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association...
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A methodology for ultimate strength assessment of ship hull girder accounting for enhanced corrosion degradation modelling
PublicationThe presented work shows a methodology for the ultimate strength assessment of a ship hull, considering enhanced corrosion modelling. The approach is based on the classical Smith method. However, the recent findings regarding the impact of corrosion degradation on ultimate strength are incorporated. To this end, the stress–strain relationships for particular elements composing ship hull cross-section are modified using a specially...
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Determining and verifying the safety integrity level of the safety instrumented systems with the uncertainty and security aspects
PublicationSafety and security aspects consist of two different group of functional requirements for the control and protection systems. In the paper it is proposed that the security analysis results can be used as a factor increasing or decreasing the risk level. It concerns a process of determining required safety integrity level of given safety functions. The authors propose a new approach for functional safety risk analysis. In this case...
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Safety integrity level verification for safety-related functions with security aspects
PublicationThe article is devoted some important issues of the functional safety analysis, in particular the safetyintegrity level (SIL) verification of safety functions to be implemented within the distributed controland protection systems with regard to cyber security aspects. The procedure for functional safety man-agement includes hazard identification, risk analysis and assessment, specification of overall safetyrequirements and definition...
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VALUATION OF EMBEDDED OPTIONS IN NON-MARKETABLE CALLABLE BONDS: A NEW NUMERICAL APPROACH
PublicationThe issue of how to price options embedded in callable bonds has attracted a lot of interest over the years. The usual bond valuation methods rely on yield curves, risk premium, and other parameters to estimate interest rates used in discounted cash flow calculations. The option to retire the bond is, however, neglected in the standard pricing models, causing a systematic overvaluation of callable bonds. In the event of a decline...
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Framework for RIDM within functional safety management process
PublicationThe functional safety management in life cycle is a complex process starting with identifying hazards and defining safety-related functions (SRFs) with risk assessment oriented at determining the safety integrity level. Another element of such life cycle is a verification of required SIL for designed safety-related system which implements safety function. Due to complexity of the problem, to overcome difficulties in safety-related...
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Modeling of event trees for the rapid scenario development
PublicationThe paper concerns the safety of ships in abnormal/damage conditions. Some conclusions following from the research associated with development of a method for safety assessment of ships in abnormal/damage conditions is presented in the paper. The method called SSAMADC (Ship Safety Assessment Method in Abnormal/Damage Conditions) is a risk-based method and is connected with application of the quantitative risk assessment QRA approach....
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Warunki hydrogeochemiczne i podatność na zanieczyszczenie wód podziemnych w zlewni górnej Raduni
PublicationThe paper presents results of long-term studies in the Kashubian Lake district that have been completed with data gathered over the last five years. The purpose of this research was to assess a temporal variability of groundwater chemical composition and to analyze risk of pollutant migration to subsurface water. Investigation indicates local, however, significant anthropogenic influence on a shallow aquifers.The assessment of...
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Microorganisms in the air within the Gdańsk-Szadółki landfill and adjacent area in 2015
Open Research DataThis data set contains the results of microbiological examination of air samples collected at Gdańsk Szadółki Landfill (Poland) in 2015. The range of examination included qualitative and quantitative assesment of selected species of bacteria and mold fungi, with particular focus on pathogenic and potentially pathogenic fungi and bacteria. The collected...
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Microorganisms in the air within the Gdańsk-Szadółki landfill and adjacent area in 2018
Open Research DataThis data set contains the results of microbiological examination of air samples collected at Gdańsk Szadółki Landfill (Poland) in 2018. The range of examination included qualitative and quantitative assesment of selected species of bacteria and mold fungi, with particular focus on pathogenic and potentially pathogenic fungi and bacteria. The collected...
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Microorganisms in the air within the Gdańsk-Szadółki landfill and adjacent area in 2017
Open Research DataThis data set contains the results of microbiological examination of air samples collected at Gdańsk Szadółki Landfill (Poland) in 2017. The range of examination included qualitative and quantitative assesment of selected species of bacteria and mold fungi, with particular focus on pathogenic and potentially pathogenic fungi and bacteria. The collected...
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Microorganisms in the air within the Gdańsk-Szadółki landfill and adjacent area in 2019
Open Research DataThis data set contains the results of microbiological examination of air samples collected at Gdańsk Szadółki Landfill (Poland) in 2019. The range of examination included qualitative and quantitative assesment of selected species of bacteria and mold fungi, with particular focus on pathogenic and potentially pathogenic fungi and bacteria. The collected...
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Assessing Metal Distribution in Diverse Incineration Ashes: Implications for Sustainable Waste Management in Case of Different Incineration Facilities
PublicationIncineration contributes about 10% of metals emission in Europe and leaching of metals from reuse or landfilling of incineration products remains a global concern. Thus, evaluating metal distribution in incineration residues is critical. The present study highlights the distribution of selected metals, Zn, Mn, Ni, Co, Fe, Cr, Al, Cu, and Pb, in incineration ashes in relation to incinerator capacities/sizes. Al was most distributed...
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Assessing climate change threats and urbanization impacts on surface runoff in Gdańsk (Poland): insights from remote sensing, machine learning and hydrological modeling
PublicationThis study investigates the impacts of Land Use/Land Cover (LULC) changes and climate change on surface runoff in Gdańsk, Poland, which is crucial for local LULC planning and urban flood risk management. The analysis employs two primary methodologies: remote sensing and hydrological modeling. Remote sensing was conducted using Google Earth Engine and Land Change Modeler in IDRISI Terrset software to analyze historical (1985–2022)...
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Surface sediments pollution due to shipwreck s/s “Stuttgart”: a multidisciplinary approach
PublicationShipwrecks may pose a serious source of pollution for marine ecosystems. For this reason, it is of great importance to perform a marine ecosystem risk assessment due to plausible wreck presence. One of elements of such an assessment is determining the state of the environment in the vicinity of the wreck. In the work presented, the results of studies on surface sediments samples collected around the s/s Stuttgart ship sunk during...
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Złote monety bulionowe – testowanie pasywnego charakteru inwestycji
PublicationCel – Wyznaczenie składu optymalnego portfela inwestycyjnego o minimalnym ryzyku, zawierającego inwestycję w polskie monety bulionowe (Orzeł Bielik) oraz inwestycję na polskiej giełdzie papierów wartościowych. Testowanie pasywnego charakteru inwestycji w monety. Metodologia badania – Konstrukcja portfeli inwestycyjnych o minimalnym ryzyku według teorii H.M. Markowitza. Autorska metoda badania pasywnego charakteru inwestycji...
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Joanna Rymaszewska prof. dr hab. n. med.
PeopleCV Joanna Rymaszewska Wroclaw University of Science and Technology, Wroclaw, Poland +48 601 98 26 24, joanna.rymaszewska@pwr.edu.pl orcid.org/0000-0001-8985-3592 2023 → Professor of Wroclaw University of Science and Technology (WUST), Poland 2011 → 2023 Professor of Wroclaw Medical University (WMU), PL 2016 → 2022 Head of the Department of Psychiatry, Wroclaw Medical University 2016 → 2022 Head of the Clinic of Psychiatry,...
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Practical Evaluation of Internet Systems' Security Mechanisms
PublicationA proposed Internet systems security layer with context-oriented security mechanisms reduces the risk associated with possible vulnerabilities. A metric of the system trust level is proposed, and then evaluated according to a university Internet system.
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New approach to urban housing - Report of ISOCARP Young Planning Professionals Workshop, Gdynia School of Urbanizm, Aesop Urban Summer School
PublicationThe workshop was organized along with the INTERNATIONAL CONFERENCE LIVING IN THE CITY – PROBLEMS AND CHALLENGES OF SHAPING HOUSING POLICY which is hosted by the City of Gdynia Poland. It was conducted in frame of Young Planning Professionals Program and 7th AESOP uropean Urban Summer School but also as the new type of the activity for the Young Planners “Gdynia School of...
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Zarządzanie bezpieczeństwem w złożonych obiektach i instalacjach krytycznych
PublicationW rozdziale scharakteryzowano wybrane metody wspomagające zarządzanie bezpieczeństwem w systemach technicznych, w tym metodę RCM (reliability-centered maintenance) polegającą na proaktywnej obsłudze, której celem jest nie dopuszczać lub przynajmniej ograniczać skutki potencjalnych uszkodzeń oraz metodę RBM (risk-based maintanance) i procedurę RIMAP (risk-based inspection and maintanance procedures) stosowaną w zarządzaniu bezpieczeństwem...
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Protection of Pedestrians as the Key Action for Implementing - Poland’s Vision Zero
PublicationWHO reports show that pedestrians account for 10 to 70% of total road crash fatalities. In Poland, pedestrians also represent a significant road safety problem. For many years, pedestrian collisions have accounted for approx. 30% of total road crashes with more than 30% of pedestrians killed. Therefore, pedestrian safety has been one of Poland’s main objectives in its road safety programs implemented over the past 20 years. The...
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Analysis of different tillage implements with respect to reduced fuel consumption, tractor operating speed and its wheel slippage
PublicationNowadays the prices of agricultural farm produced products are increasing with ant-speed and the prices of input for raising crops are increasing with rocket-speed. Therefore, there is a dire need to conduct some important studies to innovate the techniques which can lower the costs of crop production. In this context, this study was conducted to evaluate the consumption of fuel at different tillage implements, tractor operating...
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Precise Identification of Different Cervical Intraepithelial Neoplasia (CIN) Stages, Using Biomedical Engineering Combined with Data Mining and Machine Learning
PublicationCervical cancer (CC) is one of the most common female cancers worldwide. It remains a significant global health challenge, particularly affecting women in diverse regions. The pivotal role of human papillomavirus (HPV) infection in cervical carcinogenesis underscores the critical importance of diagnostic strategies targeting both HPV infection and cervical...
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Ergonomic Aspects of Transport of Patient through the Operating Theatre
PublicationOne of the most crucial decisions to be made while designing and re-modernizing an operating theatre is selecting a method of transporting the patient through the hospital’s spatial arrangement. This decision, while irrelevant at first thought, implies numerous project and functional consequences. Designing an operating theatre within a hospital is related to numerous specialist requirements with an aim of minimizing the risk of...
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Urinary Tract Infections Caused by K. pneumoniae in Kidney Transplant Recipients – Epidemiology, Virulence and Antibiotic Resistance
PublicationUrinary tract infections are the most common complication in kidney transplant recipients, possibly resulting in the deterioration of a long-term kidney allograft function and an increased risk of recipient’s death. K. pneumoniae has emerged as one of the most prevalent etiologic agents in the context of recurrent urinary tract infections, especially with multidrug resistant strains. This paper discusses the epidemiology and risk...
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Safety assurance strategies for autonomous vehicles
PublicationAssuring safety of autonomous vehicles requires that the vehicle control system can perceive the situation in the environment and react to actions of other entities. One approach to vehicle safety assurance is based on the assumption that hazardous sequences of events should be identified during hazard analysis and then some means of hazard avoidance and mitigation, like barriers, should be designed and implemented. Another approach...
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The share of investments in gold and oil using the example of selected European stock exchanges– A comparative analysis
PublicationIn this article, optimal investment portfolios with minimal risk and maximum efficiency were calculated. The portfolios were designated for ten selected European stock exchanges, based on the listings of the twenty largest companies in each of those markets. All calculations were made based on company shares only, company shares and investments in gold, shares of companies and investments in crude oil as well as shares of companies...
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Antipsychotic drug prescription sequence analysis in relation to death occurrence and cardiometabolic drug usage: A retrospective longitudinal study
PublicationThe potential role of antipsychotics in increasing cardiovascular risk of mortality is still debated. The aim of this study was to assess the death risk associated with sequences of first-generation antipsychotic (FGA) and second-generation antipsychotic (SGA) prescriptions, including clozapine and lithium, and drugs for cardiometabolic diseases. We conducted a retrospective longitudinal analysis involving 84,881 patients who received...
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Karol Dziedziul dr hab.
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Reliability data safety instrumented systems SIS from the functional safety analysis example critical instalation
Open Research DataThe dataset represents the results of an example of functional safety analysis systems is presented below. It is based on a control system, which consists of some basic components like sensors, programmable logic controllers and valves. It is a part of petrochemical critical installations. The communication between sensor logic controllers and actuators...
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Znaczenie płci w procesie zakupu marek własnych sieci handlowych – analiza wielogrupowa
PublicationThe purpose of the article is to analyze the differences in the behavior of men and women in the process of purchasing store brands (SBs). Using an established conceptual model, we intended to identify differences, depending on gender of buyers, in the size of the effects of store image and brand price-image on perceived risk and subsequently on store brand purchase intention. A total of 652 respondents participated in the study....
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Road safety information system in Poland - supporting tools and their development
PublicationAs a signatory to the UN Declaration on road safety and member of the EU, Poland has an obligation to comply with relevant EU policies and in particular to halve the overall number of road deaths by 2020. To monitor the progress in reaching the targets, the road safety situation must be evaluated and its processes understood. For this purpose regional and national road safety observatories were launched in Poland, which triggered...
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Knowledge-based functional safety and security management in hazardous industrial plants with emphasis on human factors
PublicationExisting and emerging new hazards have significant potential to impact destructively operation of technical systems, hazardous plants, and systems / networks of critical infrastructure. The programmable control and protection systems play nowadays an important role in reducing and controlling risk in the process of hazardous plant operation. It is outlined how to deal with security related hazards concerning such systems to be...
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Methodological issues of functional safety and reliability assessment of critical systems in industrial hazardous plants
PublicationThe aim of this article is to identify and discuss some methodological issues that are of interest among functional safety specialists and experts after publication of the second edition of international standards IEC 61508 and IEC 61511, including the design and implementing the safety-related functions of higher safety integrity levels and protection layers. The basic role of safety-related systems is to reduce effectively and...
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Defence in depth conception in nuclear power plants and requirements for instrumentation and control systems
PublicationThe aim of this article is to identify and discuss some issues of the safety systems’ design for nuclear power plants equipped with the light water reactors using a defence in depth (D-in-D) conception. Because the functional safety solutions play nowadays an important role for the risk control, the basic requirements for the instrumentation and control systems are specified with regard to relevant international standards. For...
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Ergonomics in Polish outpatient clinics
PublicationOutpatient clinics are structures In which ergonomics play a key role. This fact is associated with an often occurring risk of developing hospital-acquired infection. The risk increases with mistakes made in wrong planning the functional and spatial lay-out is subordinated to high utilitarian requirements, including hygienic and sanitary, and technological requirements. A properly planned structure allows to reduce dangers more...
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A Framework of A Ship Domain-Based Near-Miss Detection Method Using Mamdani Neuro-Fuzzy Classification
PublicationSafety analysis of navigation over a given area may cover application of various risk measures for ship collisions. One of them is percentage of the so called near- miss situations (potential collision situations). In this article a method of automatic detection of such situations based on the data from Automatic Identification System (AIS), is proposed. The method utilizes input parameters such as: collision risk measure based...
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Methodology for assessing the lighting of pedestrian crossings based on light intensity parameters
PublicationOne of the possible preventive measures that could improve safety at crossings is to assess the state of illumination of the lighting installation located in the transition area for pedestrians. The City of Warsaw has undertaken to comprehensively assess the pedestrian crossings to determine the level of road safety and the condition of lighting. The lighting conditions related to pedestrian crossings without traffic lights in...
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Multivariate Statistical Approach for Nephrines in Womenwith Obesity
PublicationCatecholamines are physiological regulators of carbohydrate and lipid metabolism during stress, but their chronic influence on metabolic changes in obese patients is still not clarified. The present study aimed to establish the associations between the catecholamine metabolites and metabolic syndrome (MS) components in obese women as well as to reveal the possible hidden subgroups of patients through hierarchical cluster analysis...
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Biological and mechanical properties of bone cement with nanoarticles - in vitro and in vivo research
PublicationDespite antibiotic preventive treatment both before and after implant implementation, the risks of infection are real. These infections develop at the implant surface a few months after inserting them into the body. To prevent the development of bacteria and reduce the risk of infection, implants coated with nanoparticles are used. The Mechanical Department of the Technical University of Gdansk carries out research into using bone...
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Public art in the era of urban transformations. A case study of Eduardo Paolozzi’s artistic output in Edinburgh and in London
PublicationUrban space dedicated to cultural life, entertainment or business is currently exposed to dynamic urbanistic transformations. Monumental works of art within the boundaries of cities, for years embedded in the urban landscape and awareness of viewers, are moved to other places or even destroyed. Decisions about a change of their location and context, which are fundamental aspects for the impression made by a given work of art, cause...
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Overheating of underground power cable line due to its partial exposition to solar radiation
PublicationCurrent-carrying capacity of underground power cable lines depends, among others, on thermal resistivity of the soil and cables layout: trefoil formation, flat formation with or without spacing. If conditions for heat transfer in the ground are favorable, the current-carrying capacity is relatively high. Therefore, it generates risk of the power cables overheating, if part of the cable line is located vertically in the air, to...
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Markowitz’s portfolio theory – optimal length of estimation window for gold and the biggests companies on the Warsaw Stock Exchange
PublicationThe following article is dedicated to the construction of an investment portfolio consisting of 3 investments from the Polish capital market found in the WIG20 index and from investment in gold. The purpose of the study was to determine the optimal length of the estimation window for building a portfolio with minimal risk and maximum efficiency. The length of the estimation window was also assessed in terms of the rate of return...
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Środowisko wspomagające zarządzanie ryzykiem w przedsięwzięciach informatycznych.
PublicationArtykuł prezentuje środowisko komputerowe wspierające proces zarządzania ryzykiem w przedsięwzięciach informatycznych. We wstępie wprowadzono charakterystykę procesu zarządzania ryzykiem oraz przedstawiono podział tego procesu na poszczególne fazy. Następnie omówiono potrzeby informatycznego wsparcia zarządzania ryzykiem i zaproponowano prototypowe narzędzie system Risk Guide. Opisano zakres oferowanego wsparcia i wbudowaną...
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Concept of Multifactor Method and Non-Functional Requirements Solution to Increase Resilience through Functional Safety with Cybersecurity Analysis
PublicationIn the process of designing safety systems, an integrated approach in safety and cybersecurity analysis is necessary. The paper describes a new technique of increasing resilience through integrated analysis of functional safety and cybersecurity. It is a modeling methodology based on the combination of the multifactor method utilizing modified risk graphs, used previously for Safety Integrity Level (SIL) assessment, and the Non-Functional...
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Technique for reducing erosion in large-scale circulating fluidized bed units
PublicationThis paper presents a methodology, implemented for a real industrial-scale circulating fluidized bed boiler, to mitigate the risk of heating surfaces exposed to an intensive particle erosion process. For this purpose, a machine learning algorithm was developed to support the boiler reliability management process. Having a tool that can help mitigate the risk of uncontrolled power unit failure without expensive and technically complex...
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The use of GIS tools for road infrastructure safety management
PublicationThere are many factors that influence accidents and their severity. They can be grouped within the system of man, vehicle and environment. The article focuses on how GIS tools can be used to manage road infrastructure safety. To ensure a better understanding and identification of road factors, GIS tools help with the acquisition of road parameter data. Their other role is helping with a clear and effective presentation of risk...
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Is sequential batch reactor an efficient technology to protect recipient against non-steroidal anti-inflammatory drugs and paracetamol in treated wastewater?
PublicationThe tested facility was a wastewater treatment plant (WWTP) in Swarzewo, where the wastewater treatment takes place in aeration chambers with activated sludge using sequential batch reactors (SBRs). The concentration of the following pharmaceuticals: ibuprofen, paracetamol, flurbiprofen, naproxen, diclofenac, and its metabolites 5OH-diclofenac and 4OH-diclofenac was tested in influents and effluents. Simultaneously, the conventional...
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Unconventional and user-friendly sampling techniques of semi-volatile organic compounds present in an indoor environment: An approach to human exposure assessment
PublicationThe commonly applied solutions used to assess the potential risk of human exposure to semi-volatile organic compounds (SVOCs) are based on the investigation of biological samples collected in an invasive or non-invasive manner. For SVOCs, which are typically introduced to humans through the respiratory system, dermal adsorption, or digestive system, sampling solutions generally used in the indoor environments are classified as...
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Instalacje fotowoltaiczne w budownictwie wielorodzinnym
PublicationArtykuł opisuje wpływ instalacji fotowoltaicznych na bezpieczeństwo eksploatacji budynków wielorodzinnych. W oparciu o projekty rzeczywistych obiektów przeprowadzono analizę zwiększenia ryzyka strat odgromowych, zmiany obciążenia konstrukcji dachu i wzrostu zagrożenia pożarowego na skutek montażu systemu fotowoltaicznego. Przeprowadzone obliczenia wskazują na konieczność kompleksowego podejścia do projektowania instalacji fotowoltaicznych....