Wyszukiwarka
Wyniki wyszukiwania dla: MULTIVARIATE RATIONAL INTERPOLATION
-
Synthetic strategies in construction of organic low molecular-weight carrier-drug conjugates
PublikacjaInefficient transportation of polar metabolic inhibitors through cell membranes of eukaryotic and prokaryotic cells precludes their direct use as drug candidates in chemotherapy. One of the possible solutions to this problem is application of the ‘Trojan horse’ strategy, i.e. conjugation of an active substance with a molecular carrier of organic or inorganic nature, facilitating membrane penetration. In this work, the synthetic...
-
Market Regeneration in Line with Sustainable Urban Development
PublikacjaThis article presents the study of the optimal design solutions for regeneration of marketplaces. It examines the design variants for the revitalisation of the marketplace, in particular, investment in their modernisation in order to find the most optimal model for transforming these public spaces to have a significant impact on the city’s development. The research is a comparative analysis of the implementation of regeneration...
-
Modification of quaternary structure of Candida albicans GlcN-6-P synthase and its desensitization to inhibition by UDP-GlcNAc by site-directed mutagenesis
PublikacjaSite-directed mutagenesis of the CaGFA1 gene encoding glucosamine-6-phosphate synthase from Candida albicans was performed. Desensitization of the enzyme to inhibition by UDPGlcNAc was achieved upon T487I and H492F substitutions at the UDP-GlcNAc binding site, exchange of D524, S525 and S527 for Ala at the dimer:dimer interface and construction of the tail-lock array (L434R and L460A) at the C-tail region. The first two sets if...
-
Identification of continuous systems - Practical issues of insensitivity to perturbations
PublikacjaIn this paper the issue of continuous systems estimation, insensitive to certain perturbations, is discussed. Such an approach has rational advantages, especially when robust schemes are used to assist a target system responsible for industrial diagnostics. This requires that estimated model parameters are generated on-line, and their values are reliable and to a great extent accurate. Practical hints are suggested to challenge...
-
Identification of Continuous Systems - Practical Issues of Insensitivity to Perturbations
PublikacjaIn this paper the issue of continuous systems estimation, insensitive to certain perturbations, is discussed. Such an approach has rational advantages, especially when robust schemes are used to assist a target system responsible for industrial diagnostics. This requires that estimated model parameters are generated on-line, and their values are reliable and to a great extent accurate. Practical hints are suggested to challenge...
-
A Simplistic Downlink Channel Estimation Method for NB-IoT
PublikacjaThis paper presents a downlink channel estimation method intended for a Narrowband Internet of Things (NB-IoT) access link. Due to its low computational complexity, this method is well suited for energy-efficient IoT devices, still providing acceptable reception quality in terms of signal-to-noise (SNR) performance. This paper describes the physical layer of NB-IoT within the scope of channel estimation, and also reviews existing...
-
Multiobjective Aerodynamic Optimization by Variable-Fidelity Models and Response Surface Surrogates
PublikacjaA computationally efficient procedure for multiobjective design optimization with variable-fidelity models and response surface surrogates is presented. The proposed approach uses the multiobjective evolutionary algorithm that works with a fast surrogate model, obtained with kriging interpolation of the low-fidelity model data enhanced by space-mapping correction exploiting a few high-fidelity training points. The initial Pareto...
-
Direct modulation for conventional matrix converters using analytical signals and barycentric coordinates
PublikacjaThis paper proposes the generalized direct modulation for Conventional Matrix Converters (CMC) using the concept of analytical signals and barycentric coordinates. The paper proposes a novel approach to the Pulse Width Modulation (PWM) duty cycle computing, which allows faster prototyping of direct control algorithms. The explanation of the new idea using analytical considerations demonstrating the principles of direct voltage...
-
Reduced-cost surrogate modeling of input characteristics and design optimization of dual-band antennas using response features
PublikacjaIn this article, a procedure for low-cost surrogate modeling of input characteristics of dual-band antennas has been discussed. The number of training data required for construction of an accurate model has been reduced by representing the antenna reflection response to the level of suitably defined feature points. The points are allocated to capture the critical features of the reflection characteristic, such as the frequencies...
-
Multi-Fidelity Local Surrogate Model for Computationally Efficient Microwave Component Design Optimization
PublikacjaIn order to minimize the number of evaluations of high-fidelity (“fine”) model in the optimization process, to increase the optimization speed, and to improve optimal solution accuracy, a robust and computational-efficient multi-fidelity local surrogate-model optimization method is proposed. Based on the principle of response surface approximation, the proposed method exploits the multi-fidelity coarse models and polynomial interpolation...
-
Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublikacjaThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
-
Nuclear Magnetic Resonance Metabolomics Reveals Qualitative and Quantitative Differences in the Composition of Human Breast Milk and Milk Formulas
PublikacjaCommercial formula milk (FM) constitutes the best alternative to fulfill the nutritional requirements of infants when breastfeeding is precluded. Here, we present the comparative study of polar metabolite composition of human breast milk (HBM) and seven different brands of FM by nuclear magnetic resonance spectroscopy. The results of the multivariate data analysis exposed qualitative and quantitative differences between HBM and...
-
On-line assessment of oil quality during deep frying using an electronic nose and proton transfer reaction mass spectrometry
PublikacjaWe describe a novel method for the quality assessment of oil utilized for deep frying. The method is based on the analysis of frying fumes using a custom electronic nose. The quality score could be obtained after less than 3 min of analysis and without interrupting the frying process or sampling the oil directly. The obtained results were correlated with the peroxide value using a multivariate linear regression model. The most...
-
Direct brain stimulation modulates encoding states and memory performance in humans
PublikacjaPeople often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate neural encoding states and subsequent memory outcomes. Using recordings from neurosurgical epilepsy patients with intracranially implanted electrodes, we trained multivariate classifiers to discriminate spectral activity during learning that predicted remembering from forgetting,...
-
Treatment of landfill leachate in a constructed free water surface wetland system over a decade – Identification of disturbance in process behaviour and removal of eutrophying substances and organic material
PublikacjaAn 8 ha free water surface wetland system in Örebro, Sweden, which has sediment traps followed by 10 ponds for treatment of landfill leachate in the methanogenic stage, was studied from 2003 to 2012. The wetland was irregularly loaded and the leachate characteristics showed high temporal and spatial variability, so Multivariate Statistical Process Control was chosen as the diagnostic tool for detecting anomalies prior to assessing...
-
Analysis of Induced Voltages and Power Losses in High Voltage Power Cables for Selected Methods of Cables Sheaths Bonding
PublikacjaPower is increasingly supplied to city centres with 110 kV cable lines. This is a convenient way to supply power, and practically the only one possible in areas of dense urban development. A high-voltage cable contains a coaxial metallic sheath, in which in normal operation and in fault conditions (during short-circuits) significant line-to-earth voltages can be induced, which threatens electric shock and/or damage to the cable’s...
-
Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study
PublikacjaBackground: Pre-operative discrimination of malignant from benign adnexal masses is crucial for planning additional imaging, preparation, surgery and postoperative care. This study aimed to define key ultrasound and clinical variables and develop a predictive model for calculating preoperative ovarian tumor malignancy risk in a gynecologic oncology referral center. We compared our model to a subjective ultrasound assessment (SUA)...
-
Production of six-degrees-of-freedom (6DoF) navigable audio using 30 Ambisonic microphones
PublikacjaThis paper describes a method for planning, recording, and post-production of six-degrees-of-freedom audio recorded with multiple 3rd order Ambisonic microphone arrays. The description is based on the example of recordings conducted in August 2020 with the Poznan Philharmonic Orchestra using 30 units of Zylia ZM-1S. A convenient way to prepare and organize such a big project is proposed – this involves details of stage planning,...
-
Kriging metamodels and design re‐utilization for fast parameter tuning of antenna structures
PublikacjaThe paper addresses the problem of computationally efficient electromagnetic (EM)‐driven design closure of antenna structures. The foundations of the presented approach are fast kriging interpolation metamodels, utilized for two purposes: (a) producing a good starting point for further parameter tuning, and (b) yielding a reasonable Jacobian matrix estimate to jump‐start the optimization procedure. The models are rendered using...
-
Continuous blood pressure monitoring by photoplethysmography - signal preprocessing requirements based on blood flow modelling
PublikacjaObjective. The aim of the study is to investigate the effect of the signal sampling frequency and low-pass filtering on the accuracy of the localisation of the fiducial points of the photoplethysmographic signal (PPG), and thus on the estimation of the blood pressure (i.e. the accuracy of the estimation). Approach. Statistical analysis was performed on 3,799 data samples taken from a publicly available database. Four PPGfiducial...
-
Methodology of generation of CFD meshes and 4D shape reconstruction of coronary arteries from patient-specific dynamic CT
PublikacjaDue to the difficulties in retrieving both the time‑dependent shapes of the vessels and the generation of numerical meshes for such cases, most of the simulations of blood flow in the cardiac arteries use static geometry. The article describes a methodology for generating a sequence of time‑dependent 3D shapes based on images of different resolutions and qualities acquired from ECG‑gated coronary artery CT angiography. The precision...
-
Speech Analytics Based on Machine Learning
PublikacjaIn this chapter, the process of speech data preparation for machine learning is discussed in detail. Examples of speech analytics methods applied to phonemes and allophones are shown. Further, an approach to automatic phoneme recognition involving optimized parametrization and a classifier belonging to machine learning algorithms is discussed. Feature vectors are built on the basis of descriptors coming from the music information...
-
Machine Learning and Electronic Noses for Medical Diagnostics
PublikacjaThe need for noninvasive, easy-to-use, and inexpensive methods for point-of-care diagnostics of a variety of ailments motivates researchers to develop methods for analyzing complex biological samples, in particular human breath, that could aid in screening and early diagnosis. There are hopes that electronic noses, that is, devices based on arrays of semiselective or nonselective chemical sensors, can fill this niche. Electronic...
-
Efficiency of linear and non-linear classifiers for gas identification from electrocatalytic gas sensor
PublikacjaElectrocatalytic gas sensors belong to the family of electrochemical solid state sensors. Their responses are acquired in the form of I-V plots as a result of application of cyclic voltammetry technique. In order to obtain information about the type of measured gas the multivariate data analysis and pattern classification techniques can be employed. However, there is a lack of information in literature about application of such...
-
Organizational ethics and position relationship moderators among knowledge workers: a regional study of Poland
PublikacjaThis research explores organizational ethics among knowledge workers using ICT4Ds in regional enterprises in Poland before, during, and after the COVID-19 pandemic. The study addresses the importance of understanding how ethics in organizations, particularly ethical optimism, corporate social responsibility, and top management action, have evolved across these periods. This topic is crucial as organizational ethics influence employee...
-
Combined analysis of whole human blood parameters by Raman spectroscopy and spectral-domain low-coherence interferometry
PublikacjaIn this article the simultaneous investigation of blood parameters by complementary optical methods, Raman spectroscopy and spectral-domain low-coherence interferometry, is presented. Thus, the mutual relationship between chemical and physical properties may be investigated, because low-coherence interferometry measures optical properties of the investigated object, while Raman spectroscopy gives information about its molecular...
-
The influences of the information and communication technology on the structural changes of Japanese energy sectors from 1985 through 2005: a statistical analysis
PublikacjaThe purpose of this study is to analyse the influences of information and communication technology (ICT) on the structural changes of Japanese energy sectors from 1985-2005. In this study, ICT is represented by two explanatory variables, namely: 1) computers, main parts and accessories; 2) telecommunications equipment. We employ a statistical tool in investigating the influences quantitatively, namely constrained multivariate regression...
-
Fading Modeling in Maritime Container Terminal Environments
PublikacjaIn this paper, an analytical model for slow and fast fading effects in maritime container terminals is derived, from fitting distributions to the results of measurements performed in an actual operational environment. The proposed model is composed of a set of equations, enabling to evaluate fading statistical distribution parameters for different system and environments conditions, as a function of frequency, base station antenna...
-
The effect of anthropogenic activity on BTEX, NO2, SO2, and CO concentrations in urban air of the spa city of Sopot and medium-industrialized city of Tczew located in North Poland
PublikacjaThe major goal of the present study is to compare the air quality of two urban locations situated in Northern Poland – the spa City of Sopot and the medium-industrialized city of Tczew using chemometric methods. As a criterion for the assessment of atmospheric air quality, measurements of benzene, toluene, ethylbenzene and total xylenes were used (collected from atmospheric air using diffusion-type passive samplers) as well as...
-
The Influence of Low-Temperature Disintegration on the Co-Fermentation Process of Distillation Residue and Waste-Activated Sludge
Publikacja: Innovative low-temperature disintegration (process temperature 55 ◦C and oxygen concentration 0.2 mg/dm3 ) can be an economically rational technology to intensifying energy production from renewable sources. The proposed process can achieve a degree of disintegration—under optimal conditions—of about 50%, which is excellent when compared with other methods of feed pre-treatment. The low-temperature disintegration of distillation...
-
The Matter of Decision-Making Control Over Operation Processes of Marine Power Plant Systems with the Use of their Models in the form of Semi-Markov Decision-Making Processes
PublikacjaThe article presents the possibility to control the real operation process of an arbitrary device installed in the marine power plant based on the four-state semi-Markov process, being the model of the process, which describes the transition process of operational states of the device and the transition process of its technical states. All these states are precisely defined for the ship main engine (SG). A hypothesis is proposed...
-
On jump conditions at non-material singular curves in the resultant shell thermomechanics
PublikacjaThe global, refined, resultant, two-dimensional (2D) balance laws of mass, linear and angular momenta, and energy as well as the entropy inequality were formulated by Pietraszkiewicz (2011) as exact implications of corresponding laws of 3D rational thermomechanics. In case of a shell with the regular base surface and all resultant surface fields differentiable everywhere on it and at any time instant, the local laws of the resultant...
-
Experimental and Machine-Learning-Assisted Design of Pharmaceutically Acceptable Deep Eutectic Solvents for the Solubility Improvement of Non-Selective COX Inhibitors Ibuprofen and Ketoprofen
PublikacjaDeep eutectic solvents (DESs) are commonly used in pharmaceutical applications as excellent solubilizers of active substances. This study investigated the tuning of ibuprofen and ketoprofen solubility utilizing DESs containing choline chloride or betaine as hydrogen bond acceptors and various polyols (ethylene glycol, diethylene glycol, triethylene glycol, glycerol, 1,2-propanediol, 1,3-butanediol) as hydrogen bond donors. Experimental...
-
Experimental and Machine-Learning-Assisted Design of Pharmaceutically Acceptable Deep Eutectic Solvents for the Solubility Improvement of Non-Selective COX Inhibitors Ibuprofen and Ketoprofen
PublikacjaDeep eutectic solvents (DESs) are commonly used in pharmaceutical applications as excellent solubilizers of active substances. This study investigated the tuning of ibuprofen and ketoprofen solubility utilizing DESs containing choline chloride or betaine as hydrogen bond acceptors and various polyols (ethylene glycol, diethylene glycol, triethylene glycol, glycerol, 1,2-propanediol, 1,3-butanediol) as hydrogen bond donors. Experimental...
-
USEFULNESS OF SEMI-MARKOV PROCESSES AS MODELS OF THE OPERATION PROCESSES FOR MARINE MAIN ENGINES AND OTHER MACHINES OF SHIP POWER PLANTS
PublikacjaThe paper describes the properties of semi-Markov processes and the opportunities and benefits from their use as models of the operation processes for marine combustion engines and other machines of ship power plants. The emphasis is put on the importance of the theory of semi-Markov processes for development of the theory of marine combustion engines and other machines of ship power plants, as well as for development of the operational...
-
Synthetic strategies in construction of organic macromolecular carrier–drug conjugates
PublikacjaMany metabolic inhibitors, considered potential antimicrobial or anticancer drug candidates, exhibit verylimited ability to cross the biological membranes of target cells. The restricted cellular penetration ofthose molecules is often due to their highhydrophilicity. One of the possible solutions to this problem is aconjugation of an inhibitor with a molecular organic nanocarrier. The conjugate thus formed should beable to penetrate...
-
Reduction of measurement data before Digital Terrain Model generation vs. DTM generalisation
PublikacjaModern data acquisition technologies provide large datasets that are not always necessary in its entirety to properly accomplish the goal of the study. In addition, such datasets are often cumbersome for rational processing, and their processing is time and labour consuming. Therefore, methods that enable to reduce the size of the measurement dataset, such as the generalization of the Digital Terrain Model (DTM) or the reduction...
-
Application of linear buckling sensitivity analysis to economic design of cylindrical steel silos composed of corrugated sheets and columns
PublikacjaThe paper deals with global stability of steel cylindrical silos composed of corrugated walls and vertical columns with loads imposed by a bulk solid following Eurocode 1. The optimum silo design with respect to the steel weight was based on a sensitivity analysis method. The changes of silo column profiles at each design step were performed by means of influence lines for the buckling load factor due to the unit column bending...
-
Jaromir Durkiewicz mgr
OsobyJaromir Durkiewicz jest asystentem w Katedrze Zastosowań Informatyki w Zarządzaniu Wydziału Zarządzania i Ekonomii Politechniki Gdańskiej. Magister informatyki i ekonometrii (Wydział Zarządzania Uniwersytetu Gdańskiego) oraz politologii (Wydział Nauk Społecznych Uniwersytetu Gdańskiego). Przez kilka lat zawodowo związany z branżą IT. Od 2017 r. doktorant na WZiE, gdzie we współpracy z prof. Tomaszem Janowskim prowadzi badania w...
-
KernelHive: a new workflow-based framework for multilevel high performance computing using clusters and workstations with CPUs and GPUs
PublikacjaThe paper presents a new open-source framework called KernelHive for multilevel parallelization of computations among various clusters, cluster nodes, and finally, among both CPUs and GPUs for a particular application. An application is modeled as an acyclic directed graph with a possibility to run nodes in parallel and automatic expansion of nodes (called node unrolling) depending on the number of computation units available....
-
Multi-fidelity EM simulations and constrained surrogate modelling for low-cost multi-objective design optimisation of antennas
PublikacjaIn this study, a technique for low-cost multi-objective design optimisation of antenna structures has been proposed. The proposed approach is an enhancement of a recently reported surrogate-assisted technique exploiting variable-fidelity electromagnetic (EM) simulations and auxiliary kriging interpolation surrogate, the latter utilised to produce the initial approximation of the Pareto set. A bottleneck of the procedure for higher-dimensional...
-
Marek Zienkiewicz dr inż.
OsobyDoktor inżynier Marek Hubert dwojga imion Zienkiewicz jest absolwentem Wydziału Geodezji, Inżynierii Przestrzennej i Budownictwa Uniwersytetu Warmińsko-Mazurskiego w Olsztynie. Zainteresowania naukowe w okresie studiów inżynierskich, magisterskich i doktoranckich rozwijał pod opieką przedstawicieli olsztyńskiej szkoły geodezyjnego rachunku wyrównawczego. W roku 2011 uzyskał tytuł zawodowy magistra inżyniera w zakresie geodezji...
-
Chemometric Assessment and Best-Fit Function Modelling of the Toxic Potential of Selected Food Packaging Extracts
PublikacjaFood packaging materials constitute an ever more threatening environmental pollutant. This study examined options to specifically assess the ecotoxicity of packaged wastes, such as cans, subjected to various experimental treatments (in terms of extraction media, time of exposure, and temperature) that imitate several basic conditions of the process of food production. The extracts were studied for their ecotoxicity with bioluminescent...
-
Two-particle entropy and structural ordering in liquid water
PublikacjaEntropies of simple point charge (SPC) water were calculated over the temperature range 278-363 K using the two-particle correlation function approximation. Then, the total two-particle contribution to the entropy of the system was divided into three parts, which we call translational, configurational, and orientational. The configurational term describes the contribution to entropy, which originates from spatial distribution of...
-
Heat transfer characteristics of hybrid microjet – Microchannel cooling module
PublikacjaThe paper presents experimental investigation of heat transfer intensification in a microjet–microchannel cooling module. Applied technology takes benefits from two very attractive heat removal techniques. When jets are impinging on the surface, they have a very high kinetic energy at the stagnation point, also in microchannels boundary layer is very thin allowing to obtain very high heat fluxes. Main objective of this paper was...
-
Comparison of heat transfer characteristics in surface cooling with boiling microjets of water, ethanol and HFE7100
PublikacjaThe basis of microjet technology is to produce jets which impinge the surface at the stagnation point with a very high kinetic energy. Main objective of this paper was to investigate the physical phenomena occurring on solid surfaces upon impingement of the single microjet in case of three fluids, namely water, ethanol and HFE7100. Intense heat transfer in the impact zone of microjet has been examined and described with precise...
-
Is the Concept of Zero Waste Possible to Implement in Construction?
PublikacjaThe scientifically treated problem of reusing building materials appeared in the literature more than 50 years ago. This paper includes an analysis of the characteristics of recycled building materials, which is a prerequisite for rational recycling. The analysis and simulation of building stocks at different scales has led to the conclusion that the most important link in the transformation of the construction industry towards...
-
Modeling a Traffic Remapping Attack Game in a Multi-hop Ad Hoc Network
PublikacjaIn multi-hop ad hoc networks, selfish nodes may unduly acquire high quality of service (QoS) by assigning higher priority to source packets and lower priority to transit packets. Such traffic remapping attacks (TRAs) are cheap to launch, impossible to prevent, hard to detect, and harmful to non-selfish nodes. While studied mostly in single-hop wireless network settings, TRAs have resisted analysis in multi-hop settings. In this paper...
-
Działania intuicyjne w praktyce przedsiębiorczej
PublikacjaIntuicję definiuje się jako szybkie, nieświadome i holistyczne przeczucie, które jest dynamicznym procesem poznawczym opartym na doświadczeniu i wiedzy przedsiębiorcy. Intuicja pozwala rozpoznawać okazje biznesowe i uzupełnia racjonalne podejmowanie decyzji biznesowych. Korzystanie z intuicji jest wskazane szczególnie ze względu na permanentnie zmieniające się otoczenie prowadzenia firmy oraz duży poziom niepewności, towarzyszący...
-
Investigation of ecological parameters of a gas turbine combustion chamber with steam injection for the floating production, storage, and offloading vessel
PublikacjaThe article is dedicated to the investigation of the possibility of using the contact type gas turbine cycle with steam injection into the combustion chamber for the floating production, storage, and offloading vessel in order to increase the specific power and efficiency and reduce emissions of toxic components. A new approach is proposed, associated with the use of the two-stage injection of superheated steam into a gas turbine...