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Wyniki wyszukiwania dla: FRUIT WINES
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Voltammetric and biological studies of folate-targeted non-lamellar lipid mesophases
PublikacjaFolate-targeted lipid nanostructures are promising strategies for the development of biocompatible drug delivery systems. The objective of this study was to evaluate the efficacy of drug delivery to cancer cells by folate-targeted lipid mesophases, cubosomes (CUB) and hexosomes (HEX), loaded with doxorubicin (DOX). Three cancer-derived cell lines (KB, HeLa, T98G) exhibiting different expressional levels of folate receptor protein...
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Experiment-Based Study of Heat Dissipation from the Power Cable in a Casing Pipe
PublikacjaThe paper deals with the important challenges in terms of electricity transmission by means of underground cable lines. The power cable’s performance is characterized by an ampacity that represents its maximum electric current-carrying capacity. The ampacity of power cables depends on their ability to diffuse the heat generated by the current flow into the environment. In the performed research, the analysis of the efficiency of...
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Diamond Nanofilm Normalizes Proliferation and Metabolism in Liver Cancer Cells
PublikacjaPurpose: Surgical resection of hepatocellular carcinoma can be associated with recurrence resulting from the degeneration of residual volume of the liver. The objective was to assess the possibility of using a biocompatible nanofilm, made of a colloid of diamond nanoparticles (nfND), to fill the side after tumour resection and optimize its contact with proliferating liver cells, minimizing their cancerous transformation. Methods:...
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Przegląd badań na temat Wikipedii oraz z wykorzystaniem Wikipedii jako instrument badawczego
PublikacjaW badaniach dotychczas prowadzonych w Polsce Wikipedia była zarówno przedmiotem badań, jak i instrumentem badawczym. Badania na jej temat oraz na temat skutków społecznych jej używania prowadzili przedstawiciele nauk humanistycznych, społecznych, ekonomicznych i prawnych. Dla wielu badaczy (zwłaszcza z dziedziny informatyki) Wikipedia była instrumentem pomocnym w prowadzeniu różnorodnych analiz i dociekań naukowych. Niniejszy artykuł...
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Analysis of Positioning Error and Its Impact on High Frequency Performance Parameters of Differential Signal Coupler of Differential Signal Coupler
PublikacjaThis paper presents the analysis of the effect of differential signal coupler positioning accuracy on its high frequency performance parameters for contact-less high speed chip-to-chip data transmission on PCB application. Our considerations are continuation of the previous works on differential signal coupler concept, design methodology and analysis for high speed data transmission monitoring presented in [1, 2]. The theoretical...
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Development of potent and effective SARS-CoV-2 main protease inhibitors based on maleimide analogs for the potential treatment of COVID-19
PublikacjaIn the present work, we report a new series of potent SARS-CoV-2 Main Protease (Mpro) inhibitors based on maleimide derivatives. The inhibitory activities were tested in an enzymatic assay using recombinant Mpro (3CL Protease from coronavirus SARS-CoV-2). Within the set of new Mpro inhibitors, 6e demonstrated the highest activity in the enzymatic assay with an IC50 value of 8.52 ± 0.44 mM. The IC50 value for Nirmatrelvir (PF-07321332,...
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The Belt and Road Initiative and export variety: 1996–2019
PublikacjaThis study examines the association between the Belt and Road Initiative (BRI) and export variety (EV). We propose three hypotheses on how BRI may foster export markets (destinations) or export product lines. The estimates are based on a dataset constructed specifically for this analysis, covering 183 countries and linked with trade data from 1996 to 2019. We apply the instrumental variable (IV) approach in regressions for covering the...
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Corrigendum to “Fatigue life improvement using low transformation temperature weld material with measurement of residual stress” [Int. J. Fatigue 164 (2022) 107137]
PublikacjaWelding processes often produce high levels of tensile residual stress. Low transformation temperature (LTT) welding wires utilise phase transformation strains to overcome the thermal contraction of a cooling weld. In this paper, the residual stress within each weld was quantified using the milling/strain gauge method, being the strain change measured as the weldment was milled away. The fatigue tests were conducted under uniaxial...
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Rapid Design Tuning of Miniaturized Rat-Race Couplers Using Regression-Based Equivalent Network Surrogates
PublikacjaA simple technique for fast design tuning of compact rat-race couplers is presented. Our approach involves equivalent circuit representation, corrected by nonlinear functions of frequency with coefficients extracted through nonlinear regression. At the same time, the tuning process connects two levels of coupler representation: EM simulation of the entire circuit and re-optimization of the coupler building blocks (slow-wave cells...
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Extended phase diagram of RNiC2 family: Linear scaling of the Peierls temperature
PublikacjaPhysical properties for the late-lanthanide-based RNiC2 (R = Dy, Ho, Er, and Tm) ternary compounds are reported. All the compounds show antiferromagnetic ground state with the Néel temperature ranging from 3.4 K for HoNiC2 to 8.5 K for ErNiC2. The results of the transport and galvanomagnetic properties confirm a charge density wave state at and above room temperature with transition temperatures TCDW = 284, 335, 366, and 394 K for...
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Complex Predictive Solution for Computerized Processes in Tire Industry
PublikacjaFollowing increasing market needs of productivity, cost reduction and safety requirements, computerized industry are faced to finding optimum between economic aspects of business and safety-related risk management. Modern factories equipped with computerized processes and extended diagnostic tools to support operator do not often use of all information’s which comes from the equipment. Some of the relations between the events are...
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Safety Assessment of Tram Stops
PublikacjaThe safety of public transport stops is the subject of numerous studies in large agglomerations around the world. This is due to the fact that it is a passenger exchange zone where collisions and accidents involving people getting on or off public transport vehicles most often occur. For this reason, the purpose of the article is to present the results of the safety assessment of the stop zones for two selected tram lines in Wroclaw....
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Fatigue life improvement using low transformation temperature weld material with measurement of residual stress
PublikacjaWelding processes often produce high levels of tensile residual stress. Low transformation temperature (LTT) welding wires utilise phase transformation strains to overcome the thermal contraction of a cooling weld. In this paper, the residual stress within each weld was quantified using the milling/strain gauge method, being the strain change measured as the weldment was milled away. The fatigue tests were conducted under uniaxial...
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The impact of material degradation on the resistance and reliability of truss structures
PublikacjaThe paper analyses limit load-carrying capacity and buckling load of truss towers used to support high voltage power lines. The analysed typical structure was subjected to characteristic loads and their combinations. The results were applied to assess structural resistance with regard to steel corrosion in the long-term operation. The extent of structural deterioration was assessed due to Young's modulus decrement in the course...
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On Design Optimization of Miniaturized Microscrip Dual-Band Rat-Race Coupler with Enhanced Bandwidth
PublikacjaIn the paper, a novel topology of a miniaturized wideband dual-band rat-race coupler has been presented. Small size of the circuit has been obtained by meandering transmission lines of the conventional circuit. At the same time, the number of independent geometry parameters has been increased in order to secure sufficient circuit flexibility in the context of its design optimization for dual-band operation. Optimum dimensions of...
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Accuracy assessment of mobile satellite measurements in relation to the geometrical layout of rail tracks
PublikacjaThe paper presents the campaigns of mobile satellite measurements, carried out in 2009–2015 on the railway and tram lines. The accuracy of the measurement method has been analysed on the basis of the results obtained in both horizontal and vertical planes. The track axis deviation from the defined geometric shape has been analysed in the areas clearly defined in terms of geometry, i.e. on the straight sections and sections with...
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The influence of food phytochemicals on cyclic phosphodiesterase 4 (PDE4) activity
PublikacjaCyclic phosphodiesterase 4 (PDE4) belongs to family of cyclic phosphodiesterases, which are expressed predominantly in inflammatory cells, airway smooth muscles, cardiovascular tissues and brain. Inhibitors of this family of enzymes found medicinal applications as antidepressants, antiinflamatory drugs (mainly in airway diseases) or antiasthmatics (Ibudilast). PDE4 inhibitors are also being tested for preventing the development...
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Photocatalytic ozonation using doped TiO2 catalysts for the removal of parabens in water
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Bioavailability of Tannins and Other Oligomeric Polyphenols: a Still to Be Studied Phenomenon
PublikacjaPurpose of Review Polyphenols are a group of plant secondary metabolites characterized with the presence ofmultiples of phenol structural units. Tannins are plant originated phenolic substances, which play an important role in plant defense system as well as have found applications in medicine, industry, and other fields of human activity. Despite these, the mechanisms of bioavailability of these substances are poorly studied and...
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Plasma cell myeloma - Female, 68 - Tissue image [11290630017286521]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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The effects of RNA editing in cancer tissue at different stages in carcinogenesis
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Stereo vision with Equal Baseline Multiple Camera Set (EBMCS) for obtaining depth maps of plants
PublikacjaThis paper presents a method of improving the estimation of distances between an autonomous harvesting robot and plants with ripe fruits by using the vision system based on five cameras. The system is called Equal Baseline Multiple Camera Set (EBMCS). EBMCS has some features of a camera matrix and a camera array. EBMCS is regarded as a set of stereo cameras for estimating distances by obtaining disparity maps and depth maps. This...
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Human serum interactions with phenolic and aroma substances of Kaffir(Citrus hystrix) and Key lime (Citrus aurantifolia) juices
PublikacjaTo understand the therapeutic application of polyphenols extracted from Kaffir (PolKaf) and Key (PolKey) limesdifferent analytical methods were applied. Based on quantitative analysis by two dimensional gas chromato-graphy (GC×GC) and time of flight mass spectrometry (TOFMS) it can be observed that the biggest differencesin the contents of selected terpenes of Kaffir and Key limes occur in chemical compounds such as limonene, citraland...
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Authenticity Assessment of the "Onisiówka" Nalewka Liqueurs Using Two-Dimensional Gas Chromatography and Sensory Evaluation
PublikacjaThe “Onisiówka” nalewka liqueur is a regional Polish alcoholic beverage, which is inscribed on the list of regional and traditional products of the Ministry of Agriculture and Rural Development in Poland. It is produced from multiflower honey, black elderberry flower syrup, and spirit. Due to fact that the “Onisiówka” nalewka liqueur has never been investigated, these studies are the foundation for further work on this regional...
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Modelowanie współpracy odbieraka prądu z siecią trakcyjną
PublikacjaW artykule przedstawiono aspekty oceny współpracy odbieraka prądu z górną siecią trakcyjną na podstawie porównania modeli matematycznych. Zaprezentowano modele odbieraków prądu i sieci jezdnej wskazując na ich użyteczność do oceny siły stykowej i uniesienia przewodów jezdnych. Wykonano szereg symulacji stanów dynamicznych interakcji górnej sieci trakcyjnej i odbieraka prądu dla różnych parametrów. W szczególności zwrócono uwagę...
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Measurements of the mechanical system properties of "SpeedLine magnetic" ultra-fast robot prototype for IML labeling
Dane BadawczeThe mechanical system tests of the high-speed IML labeling robot "SpeedLine Magnetic" were carried out in order to analyze the effects of the drive system's operating parameters on vibration and noise.
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Historic railway stations, documentation and revitalization of the railway infrastructure facilities - protection of cultural and social heritage
PublikacjaThe article presents problems of documentation and adaptation of buildings which constitute the cultural heritage of the railway infrastructure facilities in Pomerania in Poland. Shows the potential and possibilityto be adopted for various purposes. This problem affects many sites and buildings, railway stations, railway warehouses, residential buildings, technical buildings, water towers, trackman shelters, bridges, viaducts,...
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Ocena kształtu geometrycznego torów tramwajowych na podstawie pomiarów satelitarnych
PublikacjaW pracy przedstawiono ocenę możliwości wykorzystania dwusystemowych fazowych odbiorników GNSS (GPS/Glonass) dla realizacji pomiaru inwentaryzacyjnego linii tramwajowych. Opisano przebieg pomiarów przeprowadzonych na terenie Gdańska i uzyskane wyniki. Wykazano, że dla obszarów miejskich zastosowanie rozwiązań GNSS w oparciu o lokalną stację referencyjną może być alternatywnym podejściem względem pomiarów opartych o sieć ASG-EUPOS...
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Synthesis and biological evaluation of novel analogues of batracylin with synthetic amino acids and adenosine: an unexpected effect on centromere segregation in tumor cells through a dual inhibition of topoisomerase IIa and Aurora B
PublikacjaIn the search for new anticancer agents we designed and synthesized batracylin derivatives with linking synthetic amino acid side chains of different lengths and adenosine. Unexpectedly, we have found that in water and the culture media adenosine–amino acid–BAT conjugates form supramolecular structures and this prevents these compounds from entering cells. Consequently, these compounds exerted no biological activity when tested...
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Generalized Chebyshev Bandpass Filters With Frequency-Dependent Couplings Based on Stubs
PublikacjaThis paper presents an accurate synthesis method for inline and cross-coupled generalized Chebyshev bandpass filters with frequency-dependent couplings implemented via open and short stubs. The technique involves the synthesis of a lumped-element prototy pe in the form of a coupling matrix with a frequency-dependent term and the conversion of this prototype to a distributed-element mode l composed of sections of TEM lines. This...
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Diagnostic testing of marine propulsion systems with internal combustion engines by means of vibration measurement and results analysis
PublikacjaIn this paper selected issues concerning vibration diagnosis of the mechanical system within marine propulsion units have been presented, carried out on the basis of experimental examinations of a real object in which an exceedance of the allowable vibration’s level had been observed. Used diagnosing system has been characterised. A procedure of longitudinal and transverse vibrations shaft lines of the mechanical system within...
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Longitudinally magnetized left-handed cylindrical ferrite coupled line junction for nonreciprocal devices
PublikacjaThis paper presents investigations of longitudinally magnetized left-handed cylindrical ferrite coupled line junction for nonreciprocal devices. The proposed junction is formed as a quasi periodic arrangement of N unit cells. Each unit cell is realized as a cascade of short cylindrical ferrite coupled lines with reactance circuit composed of series capacitors and parallel inductors. The left-handed cylindrical junction with π/4...
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Organisatorische Probleme des Niederschlagwasser – Management in Polen
PublikacjaIn Polen dominiert in der Kanalisation das Trennsystem. Nur im Zentrum größerer Städte herrscht hauptsächlich das Mischsystem vor. Bezüglich Niederschlagswasser gibt es in Polen keine Festlegungen. Es gibt keine Definition der Verantwortlichkeiten für die Niederschlagswasserentsorgung sowie deren Finanzierung. Trotz Änderungen im Gesetz über die öffentliche Wasserver-und Abwasserentsorgung wurde dieses Problem bislang nicht...
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Generic emergence of classical features in quantum Darwinism
PublikacjaQuantum Darwinism posits that only specific information about a quantum system that is redundantly proliferated to many parts of its environment becomes accessible and objective, leading to the emergence of classical reality. However, it is not clear under what conditions this mechanism holds true. Here we prove that the emergence of classical features along the lines of quantum Darwinism is a general feature of any quantum dynamics:...
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Estimation of the Maximum Permissible PV Power to be Connected to the MV Grid
PublikacjaIn recent decades, a significant increase in the share of renewable energy sources in power grids at various voltage levels has been observed. A number of articles have been published highlighting emerging problems in low-voltage grids with a large share of prosumers and in medium- and high-voltage grids to which photovoltaic (PV) plants are connected. The article analyzes the medium-voltage grid in terms of the possibility of...
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Protein overproduction alters exosome secretion in Chinese hamster ovary cells
PublikacjaDespite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chi-nese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular vesicles (EVs) by protein overexpressing CHO cells was demonstrated with protein content assay, nanoparticle tracking analysis, and...
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Study of ultraviolet-visible fluorescence emission following resonant Auger decay of the 2p-1nl core-excited states of argon atoms
PublikacjaWe have studied the excitation and relaxation of Ar+ ions populated in resonant Auger decay from the Ar 2p−1nl core-excited states by using ultraviolet-visible fluorescence spectroscopy and photon-photon delayed coincidence technique. Fluorescence emission yields were measured in the photon energy range of 240-–255 eV for the 3s23p4(1D)5s(2D) → 3s23p4(1D)4p(2F) (393 nm) and 3s23p4(1D)4d(2F) → 3s23p4(1D)4p(2F) (335 nm) transitions...
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Visualization of a lifeboat motion during lowering along ship’s side
PublikacjaThis paper presents description of a computer program for motion visualization of a lifeboat lowered along ship’s side. The program is a post-processor which reads results of numerical calculations of simulated objects’ motions. The data is used to create scene composed of 3D surfaces to visualize mutual spatial positions of a lifeboat, ship’s side and water waving surface. Since the numerical data contain description of a simulation...
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Model Predictive Super-Twisting Sliding Mode Control for An Autonomous Surface Vehicle
PublikacjaThis paper presents a new robust Model Predictive Control (MPC) algorithm for trajectory tracking of an Autonomous Surface Vehicle (ASV) in presence of the time-varying external disturbances including winds, waves and ocean currents as well as dynamical uncertainties. For fulfilling the robustness property, a sliding mode control-based procedure for designing of MPC and a super-twisting term are adopted. The MPC algorithm has been...
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Overheating of underground power cable line due to its partial exposition to solar radiation
PublikacjaCurrent-carrying capacity of underground power cable lines depends, among others, on thermal resistivity of the soil and cables layout: trefoil formation, flat formation with or without spacing. If conditions for heat transfer in the ground are favorable, the current-carrying capacity is relatively high. Therefore, it generates risk of the power cables overheating, if part of the cable line is located vertically in the air, to...
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Chiral Pyrazolo[4,3-e][1,2,4]triazine Sulfonamides—Their Biological Activity, Lipophilicity, Protein Affinity, and Metabolic Transformations
PublikacjaReferring to our previous laboratory results related to the tyrosinase and urease inhibition by pyrazolo[4,3-e][1,2,4]triazine sulfonamides, we examined here in silico the mechanism of action at the molecular level of the investigated pyrazolotriazine sulfonamides by the molecular docking method. The studied compounds being evaluated for their cytotoxic effect against cancer cell lines (MCF-7, K-562) and for recombinant Abl and...
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Interpolation methods in GPR tomographic imaging of linear and volume anomalies for cultural heritage diagnostics
PublikacjaThis paper presents results of a ground penetrating radar (GPR) survey conducted in St. Joseph’s Church in Gdańsk, Poland. The aim of the study was to produce tomographic imaging of a renovated floor as well as the objects buried under the floor to detect linear and volume inclusions. The assumed track spacing was meaningfully greater than the single signal spacing in each track, which induced the need for interpolation methods...
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Monoclonal gammopathy of undetermined significance, NOS - Male, 69 - Tissue image [11290630017293191]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017291461]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Plasma cell myeloma - Male, 73 - Tissue image [11290630017283871]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Plasma cell myeloma - Male, 73 - Tissue image [11290630017282651]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Monoclonal gammopathy of undetermined significance, NOS - Male, 69 - Tissue image [11290630017291931]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Waldenstrom macroglobulinemia - Female, 50 - Tissue image [11290630017282841]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Monoclonal gammopathy of undetermined significance, NOS - Male, 69 - Tissue image [11290630017291571]
Dane BadawczeThis is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Metoda określania maksymalnej prędkości jazdy na łukach, dostosowana do specyfiki tras tramwajowych
PublikacjaW artykule określono potrzebę obliczenia prędkości z jaką maksymalnie można poruszać się pojazdem tramwajowym na wybranych odcinkach trasy. Określono jakie wartości są niezbędne do wykonania obliczeń trakcyjnych. Dostosowano metodę do dostępnych danych, pochodzących z Mobilnych Pomiarów Satelitarnych. Porównano wyniki z algorytmami przeznaczonymi dla zastosowań kolejowych. Przeprowadzone analizy wykazały, że przy zastosowaniu proponowanego...