Search results for: BIOLOGICAL ACTIVITY
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Protection and viability of fruit seeds oils by nanostructured lipid carrier (NLC) nanosuspensions
PublicationIn this paper, we focused on the development of nanostructured lipid carriers (NLCs) for dermal application. The NLC matrix was designed as a protective reservoir of biological active compounds that naturally occur in domestic fruit seed oils. Over the years, emulsions, as a popular physicochemical form of personal care products, were refined in order to obtain the best possible penetration into the skin of any bioactive compound...
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Particle size analysis of suspensions in removing of organic matter and phosphorus from waste water and surface water
PublicationIn this paper the particle size of suspended solids in the removing of organic matter and phosphorus compounds from lake- and waste- water treated in the Ecological Treatment Systems (ETS) was analyzed.The invesigated materials were taken from two ETS located in Pomerania Region/Poland. Object in Swarzewo is 3rd stage of biological treatment of municipal waste water, while object in Kartuzy has task to remove a phosphorus from...
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COVID‐19: A systematic review and update on prevention, diagnosis, and treatment
PublicationSince the rapid onset of the COVID-19 or SARS-CoV-2 pandemic in the world in 2019, extensive studies have been conducted to unveil the behavior and emission pattern of the virus in order to determine the best ways to diagnosis of virus and thereof formulate effective drugs or vaccines to combat the disease. The emergence of novel diagnostic and therapeutic techniques considering the multiplicity of reports from one side and contradictions...
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Structure of Microemulsion Formulated with Monoacylglycerols in the Presence of Polyols and Ethanol
PublicationThe influence of polyols as cosurfactants (propylene glycol PG; glycerol G) and short chain alcohol as a cosolvent (ethanol EtOH) on the formation and solubilization capacity of the systems: hexadecane/monoacylglycerols (MAG)/polyol/water:EtOH, at 60C, was investigated. Electrical conductivity measurement, and the DSC method were applied to determine the structure and type of microemulsions formed. The dimension of the droplets...
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Dissolved and colloidal organic nitrogen removal from WWTP effluents and reject waters using physical-chemical processes
PublicationFour physical-chemical processes were compared in terms of the efficiencies of dissolved and colloidal organic nitrogen (DON and CON) removal from the secondary effluents (SE) and reject water from full-scale biological nutrient removal activated sludge systems. Adsorption on activated carbon was most efficient and allowed to remove from the SE up to 80% and 100% of DON and CON, respectively. High efficiencies of DON removal from...
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Distillery Wastes as External Carbon Sources for Denitrification in Municipal Wastewater Treatment Plants
PublicationIn order to improve efficiency of N removal within the existing capacities, the denitrification process can be enhanced by adding external carbon sources. The studies on utilization of various by-products or waste materials as alternative carbon sources for denitrification have been carried out for over 20 years (Sage et al. 2006). Among several commercially available organic compounds (such as methanol, ethanol, acetic acid, glucose),...
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Soft Tissue Retraction Maneuver in Cone Beam Computed Tomography Prior to Crown-Lengthening Procedure—A Technical Note
PublicationBackground: An accurate determination of the biological width and the relationship of the cemento-enamel junction with the border of the alveolar bone is crucial during a clinical crown-lengthening (CCL) procedure. The aim of this study was to present a technical note about the retraction techniques in cone beam computed tomography (CBCT) prior to CCL, highlighting the significant enhancement in procedural accuracy and predictability...
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The Effect of Hyperbaric Storage on the Nutritional Value and Retention of Certain Bioactive Proteins in Human Milk
PublicationHuman milk (HM) contains the essential macronutrients and bioactive compounds necessary for the normal growth and development of newborns. The milk collected by human milk banks is stored frozen and pasteurized, reducing its nutritional and biological value. The purpose of this study was to determine the effect of hyperbaric storage at subzero temperatures (HS-ST) on the macronutrients and bioactive proteins in HM. As control samples,...
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In vitro enzyme kinetics and NMR-based product elucidation for glutathione S-conjugation of the anticancer unsymmetrical bisacridine C-2028 in liver microsomes and cytosol: major role of glutathione S-transferase M1-1 isoenzyme
PublicationThis work is the next step in studying the interplay between C-2028 (anticancer-active unsymmetrical bisacridine developed in our group) and the glutathione S-transferase/glutathione (GST/GSH) system. Here, we analyzed the concentration- and pH-dependent GSH conjugation of C-2028 in rat liver microsomes and cytosol. We also applied three recombinant human GST isoenzymes, which altered expression was found in various tumors. The...
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Poly-L-Lysine-functionalized fluorescent diamond particles: pH triggered fluorescence enhancement via surface charge modulation
PublicationRecently, the interest in applying fluorescent diamond particles (FDPs) containing nitrogen-vacancy (NV) centers for enhancing the mechanical and chemical properties of some materials, biological imaging, and sensing has been expanding rapidly. The unique properties of NV centers such as intensive, time-stable fluorescence, and an electron spin, which exhibits long coherence time and may be manipulated using external stimuli, such...
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Whether Carbon Nanotubes Are Capable, Promising, and Safe for Their Application in Nervous System Regeneration. Some Critical Remarks and Research Strategies
PublicationCarbon nanotubes are applied in or considered for different fields of medicine. Among them is the regeneration or rebuilding of nervous system components, which still lack substantial progress; this field is supported by carbon nanotubes to a great extent as the principal material. The limited research on this issue has involved PU/silk/MWCNTs, PCL/silk/MWCNTs, PCL/PGS/CNTs, chitin/CNTs, PGF/CNTs, CNTs/PGFs/PLDLA,MWCNTs chitosan,MWCNTs/PPy,...
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Convolutional Neural Networks for C. Elegans Muscle Age Classification Using Only Self-Learned Features
PublicationNematodes Caenorhabditis elegans (C. elegans) have been used as model organisms in a wide variety of biological studies, especially those intended to obtain a better understanding of aging and age-associated diseases. This paper focuses on automating the analysis of C. elegans imagery to classify the muscle age of nematodes based on the known and well established IICBU dataset. Unlike many modern classification methods, the proposed...
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Integrated plant-wide modelling for evaluation of the energy balance and greenhouse gas footprint in large wastewater treatment plants
PublicationModern wastewater treatment plants (WWTPs) should maintain a balance between three combined sustainability criteria, including effluent quality, energy performance and greenhouse gas (GHG) emissions. All of these criteria were considered in the integrated plant-wide model developed in this study. The proposed model incorporates new features, including: (i) the addition of associated facilities to the overall energy balance and...
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Incorporation of the complete ammonia oxidation (comammox) process for modeling nitrification in suspended growth wastewater treatment systems
PublicationThe newly discovered process complete ammonia oxidation (comammox) has changed the traditional under-standing of nitrification. In this study, three possible concepts of comammox were developed and incorporated as part of an extended two-step nitrification model. For model calibration and validation, two series of long-term biomass washout experiments were carried out at 12 ◦C and 20 ◦C in a laboratory sequencing batch reactor....
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The Use of Organic Coagulants in the Primary Precipitation Process at Wastewater Treatment Plants
PublicationMeasurements for determining the effect of chemically enhanced primary treatment (CEPT) on the efficiency of pollutant removal from wastewater were carried out using conventional inorganic coagulants PIX113 with polymer A110 (Kemipol, Police, Poland) and unconventional cationic organic coagulants Cofloc (Attana, Coalville, UK) C29510 (Kemipol, Police, Poland) and Sedifloc 575 (3F Chimica, Sandrigo, Italy). The average removal efficiency...
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The mechanisms of degradation of titanium dental implants
PublicationTitanium dental implants show very good properties, unfortunately there are still issues regarding material wear due to corrosion, implant loosening, as well as biological factors—allergic reactions and inflammation leading to rejection of the implanted material. In order to avoid performing reimplantation operations, changes in the chemical composition and/or modifications of the surface layer of the materials are used. This research...
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Hybrid systems using hydrodynamic cavitation/ultrasound/Fenton processes for effective treatment of wastewater
PublicationThe present situation of rapid growth in industrialization generates complex recalcitrant pollutants that are challenging to degrade by conventional wastewater treatment processes. The new generation pollutants such as non-metals in cosmetics or household cleaning chemicals and radioactive compounds which are recalcitrant are the emerging threat to the ecosystem. The headstrong micro and macro pollutants present in wastewater are...
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Tailoring Diffusional Fields in Zwitterion/Dopamine Copolymer Electropolymerized at Carbon Nanowalls for Sensitive Recognition of Neurotransmitters
PublicationThe importance of neurotransmitter sensing in the diagnosis and treatment of many psychological illnesses and neurodegenerative diseases is non-negotiable. For electrochemical sensors to become widespread and accurate, a long journey must be undertaken for each device, from understanding the materials at the molecular level to real applications in biological fluids. We report a modification of diamondized boron-doped carbon nanowalls...
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Impedimetric sensing of α-amino acids driven by micro-patterned 1,8-Diazafluoren-9-one into titania- boron- doped maze-like nanocarbons
PublicationThe development of impedimetric, non-faradaic label-free sensors for the detection of α-amino acids constitutes a trailblazing technology for the fast and inexpensive quantification of such biomarkers. Since α-amino acids, such as glycine and sarcosine, are basic constituents in biological processes, a variation in their concentration may be an indicator of cardiovascular diseases and metabolic disorders or neurological conditions....
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Modeling nutrient removal and energy consumption in an advanced activated sludge system under uncertainty
PublicationActivated sludge models are widely used to simulate, optimize and control performance of wastewater treatment plants (WWTP). For simulation of nutrient removal and energy consumption, kinetic parameters would need to be estimated, which requires an extensive measurement campaign. In this study, a novel methodology is proposed for modeling the performance and energy consumption of a biological nutrient removal activated sludge system...
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Possibilities of Leachate Co-Treatment Originating from Biogas Production in the Deammonification Process
PublicationIn the methane fermentation process, sewage sludge is the single substrate or serves as a co-substrate with the addition of various waste products. After the treatment stable digestate is obtained, which consists of two phases solid and liquid. Liquid phase, called as a leachate, due to the high content of nutrients must be treated before they are discharged into the final receiver. Physical and chemical methods of leachate treatment...
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Advanced Supervisory Control System Implemented at Full-Scale WWTP—A Case Study of Optimization and Energy Balance Improvement
PublicationIn modern and cost-eective Wastewater Treatment Plants (WWTPs), processes such as aeration, chemical feeds and sludge pumping are usually controlled by an operating system integrated with online sensors. The proper verification of these data-driven measurements and the control of different unit operations at the same time has a strong influence on better understanding and accurately optimizing the biochemical processes at WWTP—especially...
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Strategies for mitigating nitrous oxide production and decreasing the carbon footprint of a full-scale combined nitrogen and phosphorus removal activated sludge system
PublicationNitrous oxide (N2O) emitted from biological nutrient removal activated sludge systems contributes significantly to the total carbon footprint of modern wastewater treatment plants. In the present study, N2O production and emissions were experimentally determined in a large-scale plant (220,000 PE) employing combined nitrogen (N) and phosphorus (P) removal. As a modelling tool, the Activated Sludge Model 2d (ASM2d) was extended...
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pH-dependent composite coatings for controlled drug delivery system - Review
PublicationNowadays in case of long-term implants, the most common postoperative complications are bacterial infections, which in consequence may provoke loos- ening of the implants in the primary phase of stabilization. Bacterial infections are currently the most frequent cause of revision surgery of the implants such as hip joint endoprosthesis, knee joint endoprosthesis and dental implants. In order to provide the local and long-term antibacterial...
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Prophylaxis of Non-communicable Diseases: Why Fruits and Vegetables may be Better Chemopreventive Agents than Dietary Supplements Based on Isolated Phytochemicals?
PublicationThe World Health Organization (WHO) report from 2014 documented that non-communicable socalled civilization diseases such as cardiovascular disease, chronic respiratory diseases, cancer or type 2 diabetes are responsible for over 50% of all premature deaths in the world. Research carried out over the past 20 years has provided data suggesting that diet is an essential factor influencing the risk of development of these diseases....
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Using On-line Measurement by Electronic Nose and Computer Simulations for Real-time Control at WWTP
PublicationContinuous investigation of wastewater quality can be carried out by a device called an e-nose. One important feature of the proposed real-time control system for WWTP is that using on-line measurements by e-nose together (Figure 1) with technological sets picked on this basis by means of computer models, it is possible to change treatment process parameters, depending on the current quality of wastewater. It can be used for the...
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Influence of dissolved organic nitrogen on surface waters
PublicationThe aim of this study was to determine the susceptibility of dissolved organic nitrogen (DON) contained in biologically treated wastewater disposed from municipal wastewater treatment plants (WWTPs) to biodegradability and bioavailability in a water environment. Additionally an evaluation was performed of the participation of this organic nitrogen fraction, including bioavailable DON (bDON), in the nitrogen balance for the Baltic...
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An overview of the strategies for the deammonification process start-up and recovery after accidental operational failures
PublicationThe deammonification process has been universally acknowledged as an energy-efficient technology for sewage disposal. In contrast with traditional biological nitrogen removal technology, the deammonification process is able to remove ammonia from wastewater with the simplest nitrogen removal process because of its advantages of lower operating expenses, no organic carbon consumption, lower biomass production, lower carbon dioxide...
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Reliability of nitrogen removal processes in multistage treatment wetlands receiving high-strength wastewater
Publicationreatment wetlands have been proved to be more effective than conventional treatment processes in case of high-strength wastewater containing high concentrations of ammonium nitrogen and recalcitrant organic matter. In this study nitrogen removal processes and reliability of nitrogen removal at two identical pilot-scale multistage treatment wetlands (MTWs) receiving real, non-synthetic wastewater were discussed. The wastewater discharged...
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Reliability and efficiency of pollution removal during long-term operation of a one-stage constructed wetland system with horizontal flow
PublicationThe paper presents the results of a study of the reliability and efficiency of pollutant removal during long term operation of a one-stage constructed wetland system with horizontal flow. The flow rate of the wastewater treatment plant was 1.2 m3·d-1 during the research period. Physical and chemical analyses of raw wastewater and treated effluent were carried out in the years 1997–2010 (14 years). During this study period, 56 series...
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Analytical applications of smartphones for agricultural soil analysis
PublicationSoil is one of the most important farming resources. Appropriate managing of its quality promotes productive and sustainable agriculture. The valuable farm practice in soil quality managing is based on regular soil analysis with the aim to determine the exact amount of nutrients or other chemical, physical and biological soil properties. Soil analysis usually requires samples collection at desired sampling depth following by samples...
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Mercury in suspended matter of the Gulf of Gdańsk: Origin, distribution and transport at the land–sea interface
PublicationThe coastal regions of inland seas are particularly vulnerable to Hg pollution. An important carrier of toxic Hg in the marine environment is suspended matter originating from multiple sources. The present study was conducted in the Gulf...
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Hydration of aprotic donor solvents studied by means of FTIR spectroscopy
PublicationThe paper attempts to explain the mutual influence of nonpolar and electron-donor groups on solute hydration,the problem of big importance for biological aqueous systems. Aprotic organic solvents have been used asmodel solutes, differing in electron-donating power. Hydration of acetonitrile, acetone, 2-butanone, andtriethylamine has been studied by HDO and (partially) H2O spectra. The quantitative version of...
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Phototransformation of Amlodipine: Degradation Kinetics and Identification of Its Photoproducts
PublicationNowadays, monitoring focuses on the primary compounds and does not include degradation products formed during various biological and chemical processes. Transformation products may have the same effects to human health and the environment or sometimes they can be more toxic than the parent compound. Unfortunately, knowledge about the formation of degradation products is still limited, however, can be very important for the environmental...
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Removal of indicator bacteria from treated wastewater using physical and chemical methods. Pilot plant study.
PublicationEven after highly efficient biological processes the effluents from wastewater treatment plants may contain significant number of fecal bacteria, from 104 to 106 CFU/100 mL. Since no standards are set on the bacteriological quality of treated wastewater in Poland the elimination of bacterial contaminants is not a priority in wastewater treatment policy. Thus microbiological hazards become particularly significant in the situation...
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Emerging strategies for enhancing detection of explosives by artificial olfaction
PublicationExplosives detection systems need to be able to reliably detect a wide range of explosive materials and their vapours. The continued development and improvement of artificial olfaction techniques, including electronic nose (EN), remains important to overcome existing challenges and meet requirements posed by new improvements in the field of explosives. There is an increasingly popular trend aimed at improvement of fundamental metrological...
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Hydrophobic (deep) eutectic solvents (HDESs) as extractants for removal of pollutants from water and wastewater – A review
PublicationDeep eutectic solvents (DESs) are a new generation of solvents that attracted increasing attention in diverse applications. In last years, growing number of studies on hydrophobic (deep) eutectic solvents (HDESs) as an alternative extractants for various chemicals from aqueous environments have been reported. This article provides an overview on the usage of HDESs in liquid–liquid extraction (LLE) of different pollutants from water...
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Enhancing rheological muscle models with stochastic processes
PublicationPurpose: Biological musculoskeletal systems operate under variable conditions. Muscle stiffness, activation signals, and loads change during each movement. The presence of noise and different harmonic components in force production significantly influences the behaviour of the muscular system. Therefore, it is essential to consider these factors in numerical simulations. Methods: This study aims to develop a rheological mathematical...
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Processing of Biomass Prior to Hydrogen Fermentation and Post-Fermentative Broth Management
PublicationUsing bioconversion and simultaneous value-added product generation requires purifica- tion of the gaseous and the liquid streams before, during, and after the bioconversion process. The effect of diversified process parameters on the efficiency of biohydrogen generation via biological pro- cesses is a broad object of research. Biomass-based raw materials are often applied in investigations regarding biohydrogen generation using...
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Structural investigations of niobium-doped bioactive calcium-phosphate glass-ceramics by means of spectroscopic studies
PublicationSynthetic calcium-phosphate based glasses and glass-ceramics play a crucial role in the development of tissue engineering. These materials have a high biocompatibility with biological analogues, excellent ability to undergo varying degrees of resorbability and due to their non-toxicity and relatively high bioactivity they are commonly used as bone and dental implants. A substantial research effort is devoted to improve synthetic...
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Molecular Dynamics to Predict Cryo-EM: Capturing Transitions and Short-Lived Conformational States of Biomolecules
PublicationSingle-particle cryogenic electron microscopy (cryo-EM) has revolutionized the field of the structural biology, providing an access to the atomic resolution structures of large biomolecular complexes in their near-native environment. Today’s cryo-EM maps can frequently reach the atomic-level resolution, while often containing a range of resolutions, with conformationally variable regions obtained at 6 Å or worse. Low resolution...
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Photoresponsive Amide-Based Derivatives of Azobenzene-4,4′-Dicarboxylic Acid—Experimental and Theoretical Studies
PublicationAzobenzene derivatives are one of the most important molecular switches for biological and material science applications. Although these systems represent a well-known group of compounds, there remains a need to identify the factors influencing their photochemical properties in order to design azobenzene-based technologies in a rational way. In this contribution, we describe the synthesis and characterization of two novel amides...
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Electrically Conductive Carbon‐based (Bio)‐nanomaterials for Cardiac Tissue Engineering
PublicationA proper self-regenerating capability is lacking in human cardiac tissue which along with the alarming rate of deaths associated with cardiovascular disorders makes tissue engineering critical. Novel approaches are now being investigated in order to speedily overcome the challenges in this path. Tissue engineering has been revolutionized by the advent of nanomaterials, and later by the application of carbon-based nanomaterials...
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Denitrifcation rate in the mainstream deammonification
PublicationThe conventional processes of biological nitrogen removal based on nitrification and denitrification does not fit properly into the concept of the circular economy. As the alternative one should consider the deammonification process, which is a combination of partial nitrification (nitritation) and Anammox processes. It consists of removing ammonium nitrogen from wastewater under anaerobic conditions by a group of autotrophic microorganisms....
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Blood concentrations of a new psychoactive substance 4-chloromethcathinone (4-CMC) determined in 15 forensic cases
PublicationPurpose: The 4-chloromethcathinone (4-CMC) is a synthetic derivative of cathinone and belongs to new psychoactive substances. Neither data on the effects of 4-CMC on the human body, nor on nontoxic, toxic and lethal concentrations in biological materials have been published in the literature. This paper describes the results of an analysis of the blood concentrations of 4-CMC determined in 15 forensic cases related to nonfatal...
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Polyurethane porous scaffolds (PPS) for soft tissue regenerative medicine applications
PublicationTissue engineering requires suitable polymeric scaffolds, which act as a physical support for regenerated tissue. A promising candidate might be polyurethane (PUR) scaffold, due to the ease of the PUR properties design, which can be adjusted directly to the intended purpose. In this study, we report a successful fabrication of porous polyurethane scaffolds (PPS) using solvent casting/particulate leaching technique combined with...
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Study on a polish peat bog “Rucianka” as a source of yeast strains capable of effective phenol biodegradation
PublicationPhenol is one of the most widely distributed environmental pollutants which can be found in wastewaters and industrial effluents. Due to its toxicity and resistance to self-degradation, it could become even lethal for humans and animals. The treatment of this toxic compound is focused on psychical–chemical methods, although biological treatment of phenol is preferable for economic aspects related to relatively...
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Modeling organic nitrogen conversions in activated sludge bioreactors
PublicationFor biological nutrient removal (BNR) systems designed to maximize nitrogen removal, the effluent total nitrogen (TN) concentration may range from 2.0 to 4.0 g N/m3 with about 25-50% in the form of organic nitrogen (ON). In this study, current approaches to modeling organic N conversions (separate processes vs. constant contents of organic fractions) were compared. A new conceptual model of ON conversions was developed and combined...
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Habitat-related patterns of soft-bottom macrofaunal assemblages in a brackish, low-diversity system (southern Baltic Sea)
PublicationCoastal areas provide a high variety of sedimentary habitats that influence the structure of resident fauna even on small geographical scales. Therefore, examinations of spatial variations in benthic assemblages require background knowledge of the environmental and biotic heterogeneity of habitats in order to understand ecological processes in such areas. The effect of habitat-related abiotic and biological variables on macrofaunal...
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Cluster donation: How medical students bound certain types of tissues and biomedical research and how it affects their willingness to donate.
PublicationAlthough biomedical research requires cooperation with a large number of donors, its success also depends on the input of healthcare professionals who play a crucial role in promoting biomedical research and influencing an individual’s decision to donate one’s biospecimens that are left over after a medical procedure. This work was aimed at investigating the correlation between medical and healthcare students’ willingness to...