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Opioid Growth Factor and its Derivatives as Potential Non-toxic Multifunctional Anticancer and Analgesic Compounds
PublicationIn this paper, we review the structure-activity relationship of OGF and its analogues. We highlight also OGF derivatives with analgesic, immunomodulatory activity and the ability to penetrate the blood-brain barrier and may be used as safe agents enhancing chemotherapy efficacy and improving quality of life in cancer patients. The reviewed papers indicate that Met-enkephalin and its analogues are interesting candidates for the...
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Porównanie cystouretrografii mikcyjnej i sonocystografii mikcyjnej z użyciem ultrasonograficznego środka kontrastującego drugiej generacji w badaniu prospektywnym
PublicationThe invasiveness and exposure to radiation in voiding cystourethrography led to the introduction of alternative methods of diagnosis of vesicoureteral reflux, including contrast enhanced voiding urosonography. While there is a limited number of studies comparing these methods using new generation ultrasound contrast agents, none of them compared both methods simultaneously. This study is aimed at assessing agreement between contrast...
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Nanomaterials for photothermal and photodynamic cancer therapy
PublicationIn recent years, the role of optically sensitive nanomaterials has become powerful moieties in therapeutic techniques and has become particularly emphasized. Currently, by the extraordinary development of nanomaterials in different fields of medicine, they have found new applications. Phototherapy modalities, such as photothermal therapy (PTT) by toxic heat generation and photodynamic therapy (PDT) by reactive oxygen species, are...
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Comparison between measured and calculated underwater pressure of merchant ship
PublicationFrom 2012 The Polish Naval Academy take part in an international research project SIRAMIS, carried out in the framework of the European Defence Agency. The objective of this project is to improve the understanding of ship signature interaction with multi influence sensors in relevant and realistic scenario's. This paper describes selected results of the comparison results of sea trials and model calculations of the hydrodynamic...
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Within- and between-person factor structure of the Oldenburg Burnout Inventory: Analysis of a diary study using multilevel confirmatory factor analysis
PublicationThe study examined the factor structure of burnout, as measured with the Oldenburg Burnout Inventory. The participants were 235 employees of a public administration agency who assessed their burnout online for 10 consecutive working days. Two models were tested with multilevel confirmatory factor analysis, assuming the same one or two-factor structure at the within- and between-person levels. Both models showed a reasonable fit...
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Projekt urządzenia do odtwarzania warunków panujących w rakiecie kosmicznej
PublicationElementy wynoszone w przestrzeń kosmiczną rakietami są poddawane wymagającym warunkom takim jak przyspieszenia, drgania, przepływ ciepła, próżnia. Zanim ładunek, np. satelita zostanie zakwalifikowany do lotu, musi przejść szereg testów, które zweryfikują jego zdolność do przetrwania procesu wyniesienia. Wadą typowych testów jest oddzielne symulowanie reżimów: dynamicznego, termicznego i próżniowego, przez co warunki panujące podczas...
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Aspekty metodologiczne interdyscyplinarnej inżynierii oprogramowania
PublicationInterdyscyplinarna inżynieria oprogramowania jest nowym nurtem w inżynierii oprogramowania, który ma prowadzić do rozwiązania istniejących problemów poprzez badanie natury zjawisk i technik projektowych w kontekście interdyscyplinarnym. W referacie zidentyfikowano podstawowe zagadnienia metodologiczne, które należy wziąć pod uwagę w celu efektywnego prowadzenia badań oraz przeprowadzono ich dyskusję. Następnie podjęto próbę wyodrębnienia...
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The possibility of use keratin products in various branches of industry
PublicationBird's feather, the main by-product of the poultry industry, are not enough utilized and negatively influencing the environment. They contain large amount of keratin, the protein with high cystine content. The aim of our work was to obtain hydrolysates and isolates of keratin, which can be used in various areas of food, cosmetics, pharmaceutical industry and as animal feed. Keratin can be hydrolyzed and extracted from feather after...
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Chemometrics and Statistics | Multicriteria Decision Making
PublicationThis contribution describes the application of Multicriteria Decision Making tools in analytical chemistry. The general scheme of MCDM is presented to show its general steps. The most frequently applied in analytical sciences MCDM techniques – AHP, ELECTRE, PROMETHEE and TOPSIS – are briefly described and their advantages and disadvantages are discussed. The applications in analytical chemistry are selection of an appropriate...
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Harmony Search for Data Mining with Big Data
PublicationIn this paper, some harmony search algorithms have been proposed for data mining with big data. Three areas of big data processing have been studied to apply new metaheuristics. The first problem is related to MapReduce architecture that can be supported by a team of harmony search agents in grid infrastructure. The second dilemma involves development of harmony search in preprocessing of data series before data mining. Moreover,...
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Phylogenetic relationship and antimicrobial resistance in Escherichia coli isolated from the Reda River and the Oliwski Stream, Northern Poland = Lekooporność i przynależność filogenetyczna szczepów Escherichia Coli izolowanych z rzeki Redy i Potoku Oliwskiego
PublicationThe high abundance of fecal bacteria in surface water is usually related to poor agricultural practice, pollution caused by domesticated and wild animals as well as with septic tank failures. Identification of fecal contamination sources seems to be crucial in order to effectively estimate the inherent risk. In this study, the phylogenetic relationship of 30 isolates of E. coli, originated from surface water, was estimated by employing...
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The long-term properties of mineral-cement-emulsion mixtures
PublicationThis publication presents evaluation of long-term behavior of mineral-cement-emulsion (MCE) mixtures. MCE mixtures are among the major products of cold recycling of old asphalt pavements. They are composed by binding of the old materials reclaimed from the pavement and new mineral aggregate using two different binding agents – cement and bituminous emulsion. While bituminous emulsion dissolutes and binds materials quite fast, it...
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Determination of antifreeze substances in the airport runoff waters by solid-phase microextraction and gas chromatography–mass spectrometry method
PublicationA new method has been developed for the determination of antifreeze agents such as ethylene glycol (EG), propylene glycol (PG), and diethylene glycol (DEG) in the samples of airport runoff water. The method is based on headspace solid–phase microextraction (HS–SPME) of target analytes, which is coupled with gas chromatography–mass spectrometry (GC–MS). Until now, there was a lack of appropriate methodology for collecting reliable...
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Comparative Study of the Mechanical Behaviour of Bitumen- and Cement-Dominated Mixtures with Reclaimed Asphalt
PublicationThe bitumen emulsion-based recycling is a commonly used maintenance treatment in the rehabilitation of low-and medium-volume roads in Europe. Nevertheless, the wide range of climatic conditions across the continent resulted in the variety of mixture concepts and the requirements being adopted for various local conditions. In this regard, the most commonly used parameter to distinguish between the main mixture concepts is bitumen...
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On-line Search in Two-Dimensional Environment
PublicationWe consider the following on-line pursuit-evasion problem. A team of mobile agents called searchers starts at an arbitrary node of an unknown network. Their goal is to execute a search strategy that guarantees capturing a fast and invisible intruder regardless of its movements using as few searchers as possible. We require that the strategy is connected and monotone, that is, at each point of the execution the part of the graph...
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Experimental and Theoretical Insights into the Intermolecular Interactions in Saturated Systems of Dapsone in Conventional and Deep Eutectic Solvents
PublicationSolubility is not only a crucial physicochemical property for laboratory practice but also provides valuable insight into the mechanism of saturated system organization, as a measure of the interplay between various intermolecular interactions. The importance of these data cannot be overstated, particularly when dealing with active pharmaceutical ingredients (APIs), such as dapsone. It is a commonly used anti-inflammatory and...
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Intercultural interactions at multinational corporations' workplace: Grounded theory.
Publicationenvironments is a new challenge for employees and managers. The aim of the paper is to analyze the social interactions in multicultural environments of multinational corporations (MNCs) as well as to propose a model of intercultural social interactions in MNCs’ specifi c context. Design/methodology/approach: The grounded theory approach was applied to create a model of intercultural interactions in MNCs. The data was obtained during...
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Connected searching of weighted trees
PublicationW artykule rozważamy problem spójnego przeszukiwania drzew obciążonych. Autorzy w [L. Barriere i inni, Capture of an intruder by mobile agents, SPAA'02 (2002) 200-209] twierdzą, że istnieje wielomianowy algorytm dla problemu obliczania optymalnej strategii przeszukiwania obciążonego drzewa. W niniejszej pracy pokazano, że problem ten jest obliczeniowo trudny nawet dla wierzchołkowo-obciążonych drzew (wagi krawędzi równe 1) oraz...
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Uczenie na błędach w nauczaniu programowania w systemie e-learningu
PublicationJedną z kluczowych umiejętności, które muszą posiąść adepci programowania, stanowi umiejętność poprawiania kodu programu zawierającego błędy. Jest to działanie bardzo złożone, wymagające znajomości składni języka, rozumienia semantyki kodu, znajomości zasad testowania oraz rozumienia działania algorytmu. W artykule autor proponuje własną metodę kształtowania umiejętności poprawiania kodu programu wykorzystującą narzędzia do nauczania...
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Selected organophosphorus compounds with biological activity. Applications in medicine
PublicationThe purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...
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Pollutants in Airport Runoff Waters
PublicationRunoff waters from airport areas constitute a serious environmentalproblem. It is essential to monitor levels of pollutants emitted intothe environment and measure their toxicity on a continuous basis.The authors' aim was to critically review data on pollution fromaviation fuel combustion, aviation fuel spillage, the washing andcleaning of aircraft and airport service equipment, and the useof de-/anti-icing agents published in...
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Degradation kinetics and mechanism of pentoxifylline by ultraviolet activated peroxydisulfate
PublicationDegradation of pentoxifylline (PTX) by sodium peroxydisulfate (SPDS) assisted by UV irradiation has been investigated in deionized water. The treatment was more favorable over direct photolysis or peroxydisulfate oxidation alone. The effects of various parameters, including different dosage of oxidant agent, PTX concentration, initial solution pH levels, and the presence of inorganic ions like chloride, nitrate and carbonate have...
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Peptide conjugates of lactoferricin analogues and antimicrobials—Design, chemical synthesis, evaluation of antimicrobial activity and mammalian cytotoxicity
PublicationEight new peptide conjugates composed of modified bovine lactoferricin truncated analogues (LFcinB) and oneof the three antimicrobials — ciprofloxacin (CIP), levofloxacin (LVX), and fluconazole (FLC) — were synthesized. Four different linkers were applied to connect a peptide and an antimicrobial agent. The FLC-containing peptidic conjugates were synthesized using the “click chemistry” method. This novel approach is reported here...
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Ocena technologii informatycznych z wykorzystaniem prototypu funkcjonalnego systemu agentowego
PublicationW artykule zaprezentowano stan prac nad systemem agentowym służącym ocenie technologii informatycznych. Na obecnym etapie jest to prototyp funkcjonalny obejmujący agenty, bazę wiedzy oraz ontologię, zaś domeną objętą oceną - technologie zarządzania przedsięwzięciami, ze szczególnym uwzględnieniem tych nakierowanych na projekty IT. W tekście, poza wskazaniem oczekiwanych funkcjonalności, główny nacisk położono na weryfikację poprawności...
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Antioxidants: a premature scientific hypothesis that reshuffled the traditional food pyramid
PublicationAntioxidants present in substantial amounts in foods, plant-based products in particular, have been suggested as chemopreventive agents that can curb the development of undesirable health effects caused by oxidative stress simply by enriching diet in such compounds. This idea has been enthusiastically accepted by consumers, as well as food and pharmaceutical industry, and created great demand for products containing antioxidant...
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Knowledge risks inherent in business sustainability
PublicationSince the connection between business sustainability and knowledge risks has not been established in the literature so far, this paper provides a conceptual framework to demonstrate the possible impact of various knowledge risks on business sustainability and offers potential ways to manage and overcome these risks. The aim of this conceptual paper is to address two main questions: What are the potential effects of knowledge risks...
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Pharmaceuticals and another groups of emerging contaminants: Occurrence and sources in Admiralty Bay (King George Island, Maritime Antarctica)
PublicationEveryday live activities may introduce a wide range of chemicals into wastewater systems. In this study presence of selected types of pharmaceuticals from cardiovascular system group, nervous and muscolo-skeleton system group, antimicrobial agents, genitourinary and sex hormones were tested in the wastewater from H. Arctowski Antarctic station. Moreover, the receiver of discharged wastewater (Admiralty Bay) were also studied. Considering...
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Emotions Embodied in the SVC of an Autonomous Driver System
PublicationA concept of embodied intelligence (EI) is considered. None of such implementations can be fully identified with artificial intelligence. Projects that dare to approach AI and EI should be based on both the AI concepts (symbolic and sub-symbolic), in solving real problems of perception and decision-making. Therefore, the EI, in this paper, is understood as a methodology that uses all available resources and algorithms from the...
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Hybrid approach to ontology specification and development
PublicationIn this chapter a first draft of a hybrid ontology development approach is presented. The context of this method encompasses the multi-agent system equipped with knowledge bases and inferring engine. The process of ontology engineering appears as a complex issue, as it addresses different point-views of both, a client and a modeler with a requirements/system analyst. Regarding this, an approach based on the knowledge preprocessing...
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Evaluating Security and Resilience of Critical Networked Infrastructures after Stuxnet
PublicationThe chapter presents the current configuration of the simulation environment for the evaluations of the security and resilience of critical networked infrastructures, which enables simulations of Stuxnet-like attacks. The configuration includes new features added to the MAlSim - Mobile Agent Malware Simulator after the advent of Stuxnet in reference to the experiments aiming at the security evaluation of a power plant which we...
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Comparison of antimicrobial activity of selected, commercially available wound dressing materials
PublicationOBJECTIVE: The aim of our study was to examine the antimicrobial potential of eight selected, commercially available wound dressings containing different antimicrobial agents: silver, chlorhexidine acetate, povidone-iodine, and manuka honey. METHOD: The materials were tested against four reference strains of bacteria: Staphylococcus aureus (PCM 2051), Staphylococcus epidermidis (PCM 2118), Pseudomonas aeruginosa (ATCC 27853),...
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Collective citizens' behavior modelling with support of the Internet of Things and Big Data
PublicationIn this paper, collective human behaviors are modelled by a development of Big Data mining related to the Internet of Things. Some studies under MapReduce architectures have been carried out to improve an efficiency of Big Data mining. Intelligent agents in data mining have been analyzed for smart city systems, as well as data mining has been described by genetic programming. Furthermore, artificial neural networks have been discussed...
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A document-centric processing paradigm for collaborative computing
PublicationKlasyczne modele przetwarzania rozproszonego zakładają, że dokumenty są biernymi obiektami, które rozsyła się w formie komunikatów lub pobiera z serwerów do przetwarzania jako pliki.W artykule przedstawiono koncepcję dokumentu jako aktywnego obiektu, zdolnego do samodzielnej migracji miedzy węzłami sieci i interakcji z użytkownikami w ich lokalnym środowisku. Takie podejście jest szczególnie przydatne do realizacji procesów biznesowych...
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"Z budowy osiedla robotniczego Spółki PAGED" czyli w trosce o wydajność pracownika portowego w międzywojennej Gdyni
PublicationGdynia w pierwszych latach swojego istnienia zmagała się z poważnym niedoborem mieszkań dla mas robotniczych pracujących przy budowie portu i miasta. Artykuł przedstawia tematykę wzorcowego osiedla robotniczego w Gdyni zrealizowanego w lata 1935-1936 przez spółkę Polska Agencja Eksportu Drewna PAGED. Zaprezentowany materiał porusza kwestie związane z planem, budową i architekturą kolonii robotniczej PAGRD-u, warunkami mieszkaniowymi...
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Protokół głosowania większościowego w narzędziu wsparcia decyzji handlowych
PublicationIstnieje szerokie spektrum narzędzi i metod wspierających decyzje handlowe, lecz brakuj jasnych reguł ich stosowania. Zaproponowano samoorganizujacy się system agentowy do wspierania decyzji handlowych. System bazując na glosowaniu z dynamicznymi wagami, wskazuje efektywne indykatory na podstawie ich poprzednich osiągnięć. Przedstawiono analizę formalną i wyniki weryfikacji, potwierdzającej cechy rozwiązania.
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Properties of New Composite Materials Based on Hydroxyapatite Ceramic and Cross-Linked Gelatin for Biomedical Applications
PublicationThe main aim of the research was to develop a new biocompatible and injectable composite with the potential for application as a bone-to-implant bonding material or as a bone substitute. A composite based on hydroxyapatite, gelatin, and two various types of commercially available transglutaminase (TgBDF/TgSNF), as a cross-linking agent, was proposed. To evaluate the impacts of composite content and processing parameters on various...
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Epoxy Composites Filled with Natural Calcium Carbonate. 1. Epoxy Composites Obtained in the Presence of Monoperoxy Derivative of Epidian-6 Epoxy Resin
PublicationPhysico-mechanical properties of the products based on filled epoxy-oligomeric mixtures composed of Epidian-5 epoxy resin, oligoesteracrylate TGM-3 and monoperoxide derivative of Epidian-6 epoxy resin (PO) have been investigated. CaCO3 was used as a filler and polyethylene polyamine was a curing agent. The effect of PO and CaCO3 on the gel-fraction content and physico-mechanical properties was examined. Using a scanning electron...
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Methodological challenges in social entrepreneurship – on the nexus of economics and management area
PublicationIn this paper we make an attempt distinguishing challenges in SE research agenda in Polish and beyond. We identify what can impede the development of this area in Polish discourse These challenges vary in scope. They involve the dilemma between either economics or management as disciplinary settings. Also the understanding of social economy as such determines the chaos. Additionally, divergences in paradigms where researchers situate...
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Framing the Temporal Dimensions of a Brand
PublicationDrawing on existing research dealing with time in brand and brand management, this paper aims at providing a comprehensive and coherent framework of some time-related concepts, with a special emphasis on what happens when a brand reaches the senescence stage. In addition, it strives to consider what happens when a brand becomes long-lived enough, looking at the brand’s customer base. While undoubtedly time affects customers’ age...
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Biobójcze wykończenie tkanin
PublicationThe problem of nosocomial infections is nothing new. In places, where people, whose immune system is weakened, are gathered and subjected to various kinds of treatments, the risk of infection increases considerably. The use of textiles with biocidal finishing, which contains nanoAg and nanoCu, may give an additional protection against nosocominal infections. This article presents the latest information regarding various methods...
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From Individual to Collective: Intelligence Amplification with Bio-Inspired Decisional DNA and its Extensions
PublicationIn nature, deoxyribonucleic acid (DNA) contains the genetic instructions used in the development and functioning of all known living organisms. The idea behind our vision is to develop an artificial system, an architecture that would support discovering, adding, storing, improving and sharing information and knowledge among agents and organizations through experience. We propose a novel Knowledge Representation (KR) approach in...
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Preliminary study of linear viscoelasticity limits of cold recycled mixtures determined in Simple Performance Tester (SPT)
PublicationThe publication presents methodology developed for determination of linear viscoelasticity limits for cold recycled mixtures with cement and bituminous emulsion using Simple Performance Tester (SPT). Methodology was verified on reference materials (PCV and steel dummy specimens, cement concrete and asphalt concrete) to comply with elasticity and viscoelasticity theory. The developed methodology enabled determination of linear viscoelasticity...
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On the Importance of Resilience Engineering for Networked Systems in a Changing World
PublicationResilience is featured increasingly often in the media, usually applied to society when faced, for example, with disasters such as flooding and the enormous challenges that the Covid-19 pandemic posed. There are now many resilience-related discussion groups worldwide, and some standards initiatives devoted in particular to city resilience. However, there is relatively little explicit interest in resilience engineering for communication...
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Application of Majority Voting Protocols to Supporting Trading Decisions
PublicationA broad spectrum of analysis and prediction indicators and methods exists to support trading decisions, but no hard knowledge exist to tell in advance which of them will fit best in a given timeframe. To support trading decisions, a multi-agent self-organizing system has been proposed. The system is based on history based dynamic weight voting and selects the right indicators based on their past performance. The formal analysis...
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APPLICATION OF MAJORITY VOTING PROTOCOLS TO SUPPORTING TRADING DECISIONS
PublicationA broad spectrum of analysis and prediction indicators and methods exists to support trading decisions, but no hard knowledge exist to tell in advance which of them will fit best in a given timeframe. To support trading decisions, a multi-agent self-organizing system has been proposed. The system is based on history based dynamic weight voting and selects the right indicators based on their past performance. The formal analysis...
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Factors causing degradation of sulfadimetoxine
PublicationSulfadimetoxine is a representative of sulfonamide drugs which presence inhibits growth of activated sludge bacteria, rhat is necessary for the effective mineralization of organic and inorganic contaminants. Therefore factors which con prevent this situation are searched. Aim of this study is selection of conditions causing efficien degradation of the drug- sulfadimetoxine. The impact of such aspects as : the type of oxidizing...
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Microwave-assisted silication of potato starch
PublicationSilication of potato starch was performed by microwave irradiation and convectional heating of starch with sodium metasilicate. The study has shown that microwaves offered more selective silication thanconvectional heating. Depending on the dose of metasilicate products of either monoesterification or crosslinking esterification were formed. Increase in the amount of the silicating agent favoured crosslinking of starch. In the...
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Zrównoważony rozwój lokalny. Podstawy teoretyczne i działania praktyczne
PublicationRozwój zrównoważony to jedna z koncepcji rozwoju lokalnego. Celem monografii jest prezentacja podstaw tego rozwoju na poziomie lokalnym oraz ukazanie jego przejawów i działań praktycznych w sferach gospodarczej, społecznej i ekologicznej, ze szczególnym uwzględnieniem dwóch wewnętrznych czynników rozwojowych – turystyki i oświaty. W pierwszym rozdziale przedstawiono teoretyczne podstawy rozwoju lokalnego. Omówiono najpowszechniej...
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Relevance of the EU Structural Funds’ Allocation to the Needs of Combating Air Pollution in Poland. Analysis of the Operational Programmes of Regions Threatened With Critical Air Pollution from Distributed Energy Sources
PublicationRecent years, the European Environmental Agency, has been reporting air quality parameters in Poland, as the poorest among all the EU countries. Despite of adoption of the EU legislation on energy efficiency and energy performance of buildings, existing legal solutions occur insufficient in reducing air pollution in Polish regions. Lack of an effective schemes supporting complex thermal renovation of buildings, exchange of inefficient...
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Władza misjonarzy. Zmierzch i świt świeckiej religii w Dolinie Krzemowej
Publication"Władza misjonarzy" to książka o misjonarskim zapale zmieniania świata i o kryzysie świeckiej religii towarzyszącej liderom nowych technologii, o ich świętokradztwach i sprofesjonalizowanej pokucie mającej przywrócić harmonię technologicznego raju na ziemi z Alphabetem, Metą, Apple i TikTokiem w roli głównej. Także o skruszonych inżynierach, żałujących każdej chwili, którą poświęcili na wymyślanie uzależniających algorytmicznych rozwiązań...