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Effects of scatter plot initial solutions on regular grid facility layout algorithms in typical production models
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Impact of Feature Selection Methods on the Predictive Performance of Software Defect Prediction Models: An Extensive Empirical Study
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Three-Dimensional Models of Liver Vessels for Navigation during Laparotomic Attenuation of Intrahepatic Portosystemic Shunt in Dogs
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Selected mice models based on APP, MAPT and presenilin gene mutations in research on the pathogenesis of Alzheimer’s disease
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3D Morphable Models Application for Expanding Face Database Limited to Single Frontal Face Per Person
Publikacja1. Zaprezentowany materiał dotyczył badań nad rozszerzeniem dysponowanej bazy wzorców wizerunków twarzy, o dodatkowe wzorce z wariacją w ustawieniu. Dodatkowe wzorce były usyskiwane poprzez przejście z wizerunku twarzy 2D na model 3D, zasymulowanie zadanego ustawienia i powrót do dziedziny 2D (poprzez rzutowanie 3D->2D). W fazie konstrukcji modelu 3D, z wizerunku 2D była ściągana zarówno tekstura twarzy jak i siatka punktów charakterystycznych....
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Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Machine-Learning-Based Global Optimization of Microwave Passives with Variable-Fidelity EM Models and Response Features
PublikacjaMaximizing microwave passive component performance demands precise parameter tuning, particularly as modern circuits grow increasingly intricate. Yet, achieving this often requires a comprehensive approach due to their complex geometries and miniaturized structures. However, the computational burden of optimizing these components via full-wave electromagnetic (EM) simulations is substantial. EM analysis remains crucial for circuit...
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Low-Cost Quasi-Global Optimization of Expensive Electromagnetic Simulation Models by Inverse Surrogates and Response Features
PublikacjaConceptual design of contemporary high-frequency structures is typically followed by a careful tuning of their parameters, predominantly the geometry ones. The process aims at improving the relevant performance figures, and may be quite expensive. The reason is that conventional design methods, e.g., based on analytical or equivalent network models, often only yield rough initial designs. This is especially the case for miniaturized...
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Volatile Compound Emissions from Stereolithography Three-Dimensional Printed Cured Resin Models for Biomedical Applications
PublikacjaStereolithography three-dimensional printing is used increasingly in biomedical applications to create components for use in healthcare and therapy. The exposure of patients to volatile organic compounds (VOCs) emitted from cured resins represents an element of concern in such applications. Here, we investigate the biocompatibility in relation to inhalation exposure of volatile emissions of three different cured commercial resins...
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A new anisotropic bending model for nonlinear shells: Comparison with existing models and isogeometric finite element implementation
PublikacjaA new nonlinear hyperelastic bending model for shells formulated directly in surface form is presented, and compared to four existing prominent bending models. Through an essential set of elementary nonlinear bending test cases, the membrane and bending stresses of each model are examined analytically. Only the proposed bending model passes all the test cases, while the other bending models either fail or only pass the test cases for...
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublikacjaMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Cobalt(II) tri-tert-butoxysilanethiolates: in search of models for catalytic metal site of liver alcohol dehydrogenase
PublikacjaPrzeprowadzono syntezę trzech kompleksów: [Co{SSi(OBut)3}2(NH3)(L-pic)],[Co{SSi(OBut)3}2(NH3)2]xMeCN i [Co{SSi(OBut)3}3(H2O)][NHEt3]. Kompleksy są monomeryczne, dla nich wyznaczono strukturę krystalograficzną. Kompleks [Co{SSi(OBut)3(NH3)(L-pic)] o rdzeniu CoN2OS2 posiada dwa różne ligandy azotowe, zaś [Co{SSi(OBut)3(L-pic)] stanowi substrat do syntezy związku modelującego centrum katalityczne LADH.
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Constructing genuinely entangled multipartite states with applications to local hidden variables and local hidden states models
PublikacjaBuilding upon the results of R. Augusiak et al. [Phys. Rev. Lett. 115, 030404 (2015)] we develop a general approach to the generation of genuinely entangled multipartite states of any number of parties from genuinely entangled states of a fixed number of parties, in particular, the bipartite entangled ones. In our approach, certain isometries whose output subspaces are either symmetric or genuinely entangled in some multipartite...
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Surface sliding in human abdominal wall numerical models: Comparison of single-surface and multi-surface composites
PublikacjaDetermining mechanical properties of abdominal soft tissues requires a coupled experimental-numerical study, but first an appropriate numerical model needs to be built. Precise modeling of human abdominal wall mechanics is difficult because of its complicated multi-layer composition and large variation between specimens. There are several approaches concerning simplification of numerical models, but it is unclear how far one could...
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Results of the application of tropospheric corrections from different troposphere models for precise GPS rapid static positioning
PublikacjaIn many surveying applications, determination of accurate heights is of significant interest. The delay caused by the neutral atmosphere is one of the main factors limiting the accuracy of GPS positioning and affecting mainly the height coordinate component rather than horizontal ones. Estimation of the zenith total delay is a commonly used technique for accounting for the tropospheric delay in static positioning. However, in the...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Improving Accuracy of Respiratory Rate Estimation by Restoring High Resolution Features With Transformers and Recursive Convolutional Models
PublikacjaNon-contact evaluation of vital signs has been becoming increasingly important, especially in light of the COVID- 19 pandemic, which is causing the whole world to examine people’s interactions in public places at a scale never seen before. However, evaluating one’s vital signs can be a relatively complex procedure, which requires both time and physical contact between examiner and examinee. These re- quirements limit the number...
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Discrete-time predictive control design based on overparameterized delay-plant models and identified cancellation order.
PublikacjaPraca dotyczy uogólnionego sterowania predykcyjnego (GPC) obiektami opisanymi dyskretnoczasowymi modelami CARIMA z uproszczeniami (nieminimalnych, przeparametryzowanych) oraz o niezerowym opóźnieniu transportowym. Optymalne sterowanie predykcyjne wyznacza się na podstawie minimalnowariancyjnego oszacowania przyszłej odpowiedzi sterowanego obiektu. Poprzez analizę warunków rozwiązywalności zadania syntezy sterownika GPC, sformułowano...
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Application of enhanced elasto-plastic damage models to concrete under quasi-static and dynamic cyclic loading
PublikacjaArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych zginaniu w czasie cyklicznego obciążenia. Do symulacji zastosowano 3 połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano bezpośrednio z doświadczeniami.
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Comparison of continuous and discontinuous constitutive models to simulate concrete behaviour under mixed mode failure conditions
PublikacjaW artykule porównano modele MES ciągłe i nieciągłe do symulacji zachowania betonu w warunkach mieszanego zniszczenia. W ramach modeli ciągłych zastosowano modele sprężysto-plastyczne oraz modele z redukcją sztywności sprężystej i nielokalnym osłabieniem. W ramach modeli nieciągłych zastosowano XFEM. Przedmiotem obliczeń były strefy lokalizacji i rysy w warunkach mieszanego zniszczenia wg testu doświadczalnego Nooru-Mohameda.
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FE-analysis of the beaviour of concrete elements with coupled elasto-plastic-damage models with non-local softening
PublikacjaArtykuł omawia wyniki symulacji zachowania sie elementów betonowych poddanych cyklicznemu obciążeniu. Do symulacji zastosowano połączone modele sprężysto-plastyczne z degradacją sztywności i z nielokalnym osłabieniem. Wyniki symulacji porównano z doswiadczeniami.
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FE-modelling of concrete behaviour under mixed mode conditions with non-local and cohesive constitutive models.
PublikacjaW artykule przedstawiono wyniki symulacji rys zaokrąglonych w elementach betonowych w warunkach mieszanego sposobu obciążenia. Symulacje wykonano przy zastosowaniu modelu rys kohezyjnych i modeli mechaniki ośrodka ciągłego z nielokalnym osłabieniem.. Wyniki symulacji porównano z doświadczeniami.
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Limits of enhanced of macro- and meso-scale continuum models for studying size effect in concrete under tension
PublikacjaThe paper investigates a mechanical quasi-static size effect in concrete during splitting tension at the macro- and meso-level. In experiments, five different diameters of cylindrical concrete specimens were tested. Twodimensional plane strain finite element (FE) simulations were carried out to reproduce the experimental size effect. The size effect in experiments by Carmona et al. was also simulated. Two enhanced continuum concrete...
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Recent advances in high-frequency modeling by means of domain confinement and nested kriging
PublikacjaDevelopment of modern high-frequency components and circuits is heavily based on full-wave electromagnetic (EM) simulation tools. Some phenomena, although important from the point of view of the system performance, e.g., EM cross-coupling effects, feed radiation in antenna arrays, substrate anisotropy, cannot be adequately accounted for using simpler means such as equivalent network representations. Consequently, the involvement...
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A Concept of Freight Traffic Flow Regulations in the City of Gdansk
PublikacjaThis paper presents a review of state-of-art efforts in urban freight transport modelling in the context of their requirements and applicability as a basis for evaluation of city's freight transport policy. Freight transport mirrors all aspects of the city's economic activity and for that reason its proper planning is of extreme importance. However, urban freight system may be considered as the most varied and fragmented element...
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Exploring the Solubility Limits of Edaravone in Neat Solvents and Binary Mixtures: Experimental and Machine Learning Study
PublikacjaThis study explores the edaravone solubility space encompassing both neat and binary dissolution media. Efforts were made to reveal the inherent concentration limits of common pure and mixed solvents. For this purpose, the published solubility data of the title drug were scrupulously inspected and cured, which made the dataset consistent and coherent. However, the lack of some important types of solvents in the collection called...
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Graph Neural Networks and Structural Information on Ionic Liquids: A Cheminformatics Study on Molecular Physicochemical Property Prediction
PublikacjaIonic liquids (ILs) provide a promising solution in many industrial applications, such as solvents, absorbents, electrolytes, catalysts, lubricants, and many others. However, due to the enormous variety of their structures, uncovering or designing those with optimal attributes requires expensive and exhaustive simulations and experiments. For these reasons, searching for an efficient theoretical tool for finding the relationship...
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A Proposed Soft Computing Model for Ultimate Strength Estimation of FRP-Confined Concrete Cylinders
PublikacjaIn this paper, the feed-forward backpropagation neural network (FFBPNN) is used to propose a new formulation for predicting the compressive strength of fiber-reinforced polymer (FRP)-confined concrete cylinders. A set of experimental data has been considered in the analysis. The data include information about the dimensions of the concrete cylinders (diameter, length) and the total thickness of FRP layers, unconfined ultimate concrete...
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Financial markets diffusion patterns. The case of Mexican investment funds
PublikacjaExchange traded funds (ETFs) are one of the most influential financial innovations, reshaping the investment funds market in many countries, including Mexico. Due to their similar investment objectives, ETFs are considered substitutes for mutual funds. The aim of the article is to provide an in-depth insight into the issues associated with the development of financial markets in Mexico...
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Modeling protein structures with the coarse-grained UNRES force field in the CASP14 experiment
PublikacjaThe UNited RESidue (UNRES) force field was tested in the 14th Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP14), in which larger oligomeric and multimeric targets were present compared to previous editions. Three prediction modes were tested (i) ab initio (the UNRES group), (ii) contact-assisted (the UNRES- contact group), and (iii) template-assisted (the UNRES-template...
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Self-advocates with intellectual disability about their work as social educators – a qualitative Polish study
PublikacjaThe paper presents the opinions of self-advocates with mild intellectual disability about their work as social educators – public self-advocates raising disability awareness. Six semi-structured individual interviews were conducted. Data was analyzed within the framework of Interpretative Phenomenological Analysis. The themes which emerged from the interviews comprise: the motives of educators to work as self-advocates, opportunities...
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Using Redis supported by NVRAM in HPC applications
PublikacjaNowadays, the efficiency of storage systems is a bottleneck in many modern HPC clusters. High performance in the traditional approach – processing using files – is often difficult to obtain because of a model’s complexity and its read/write patterns. An alternative approach is to apply a key-value database, which usually has low latency and scales well. On the other hand, many key-value stores suffer from a limitation of memory...
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What matters most to patients? On the Core Determinants of Patient Experience from Free Text Feedback
PublikacjaFree-text feedback from patients is increasingly used for improving the quality of healthcare services and systems. A major reason for the growing interest in harnessing free-text feedback is the belief that it provides richer information about what patients want and care about. The use of computational approaches such as structural topic modelling for analysing large unstructured textual data such as free-text feedback from patients...
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Simulations of the Derecho Event in Poland of 11th August 2017 Using WRF Model
PublikacjaThis series contains datasets related to the forecasting of a severe weather event, a derecho, in Poland on 11 August 2017. The simulations were conducted using the Weather Research and Forecasting (WRF) model version 4.2.1 with different initial and boundary conditions of the pressure and model levels derived from 5 global models: Global Forecast System (GFS), Global Data Assimilation System (GDAS), European Centre for Medium-Range...
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Development of the System Assurance Reference Model for Generating Modular Assurance Cases
PublikacjaAssurance cases are structured arguments used to demonstrate specific system properties such as safety or security. They are used in many industrial sectors including automotive, aviation and medical devices. Larger assurance cases are usually divided into modules to manage the complexity and distribute the work. Each of the modules is developed to address specific goals allocated to the specific objects i.e. components of the...
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Clinical anatomy of the spatial structure of the right ventricular outflow trac
PublikacjaBackground. The right ventricular outflow tract (RVOT) is located above the supraventricular crest and reaches the level of the pulmonary valve. Detailed knowledge of the RVOT spatial structure and its morphology is extremely important for cardiac invasive therapeutic procedures. Objectives. To examine the spatial structure of the RVOT using virtual models of the right ventricle (RV) interior obtained post mortem. Material and...
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An improvement of body surface area formulas using the 3D scanning technique
PublikacjaObjectives: Body surface area (BSA) is one of the major parameters used in several medical fields. However, there are concerns raised about its usefulness, mostly due to the ambiguity of its estimation. Material and Methods: Authors have conducted a voluntary study to investigate BSA distribution and estimation in a group of 179 adult people of various sex, age, and physique. Here, there is provided an extended analysis of the...
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Monitoring the gas turbine start-up phase on the platform using a hierarchical model based on Multi-Layer Perceptron networks
PublikacjaVery often, the operation of diagnostic systems is related to the evaluation of process functionality, where the diagnostics is carried out using reference models prepared on the basis of the process description in the nominal state. The main goal of the work is to develop a hierarchical gas turbine reference model for the estimation of start-up parameters based on multi-layer perceptron neural networks. A functional decomposition...
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EFFICIENCY OF HEALTHCARE SYSTEMS IN EUROPEAN COUNTRIES - THE DEA NETWORK APPROACH
PublikacjaHealthcare systems in Europe are constantly undergoing reforms which adapt them to social, economic and political requirements. The aim of this article is to examine the efficiency of healthcare systems in 30 European countries in 2014. The Network Data Envelopment Analysis (NDEA) model was used. The efficiency of the countries’ overall health systems and their two main components were examined: the public health system and the...
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Expedited constrained multi-objective aerodynamic shape optimization by means of physics-based surrogates
PublikacjaIn the paper, computationally efficient constrained multi-objective design optimization of transonic airfoil profiles is considered. Our methodology focuses on fixed-lift design aimed at finding the best possible trade-offs between the two objectives: minimization of the drag coefficient and maximization of the pitching moment. The algorithm presented here exploits the surrogate-based optimization principle, variable-fidelity computational...
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SAWING PROCESS AS A NEW ALTERNATIVE WAY OF DETERMINING SOME WOOD PROPERTIES
PublikacjaCutting forces (power) could be considered from a point of view of modern fracture mechanics. The developed cutting model, derived from fracture mechanics, includes work of separation (fracture toughness) in addition to plasticity and friction, and also dullness of the cutting edge described by the cutting edge radius. Moreover, forecasting of the shear plane angle for the cutting models, broaden possibilities of energetic effects...
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Maximizing SDN resilience to node‐targeted attacks through joint optimization of the primary and backup controllers placements
PublikacjaIn Software Defined Networks (SDN) packet data switches are configured by a limited number of SDN controllers, which respond to queries for packet forwarding decisions from the switches. To enable optimal control of switches in real time the placement of controllers at network nodes must guarantee that the controller-to-controller and switch-to-controller communications delays are bounded. Apart from the primary controllers that...
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Wind Conditions at Pedestrian Level in Different Types of Residential Urban Development for a High Degree of Land Use Efficiency
PublikacjaThe paper concerns wind conditions around urban building development at the pedestrian level. The article aims to identify aerodynamic phenomena around three types of multi-family housing developmentswith different forms and the same urban parameters of building development intensity (high intensity was taken into account). The aim of the research was mainly to achieve qualitative results that would lead to understanding fundamental...
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MARSTRUCT benchmark study on nonlinear FE simulation of an experiment of an indenter impact with a ship side-shell structure
PublikacjaThis paper presents a benchmark study on collision simulations that was initiated by the MARSTRUCT Virtual Institute. The objective was to compare assumptions, finite element models, modelling techniques and experiences between established researchers within the field. Fifteen research groups world-wide participated in the study. An experiment involving a rigid indenter penetrating a ship-like side structure was used as the case...
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Performance‐driven modeling of compact couplers in restricted domains
PublikacjaFast surrogate models can play an important role in reducing the cost of EM-driven design closure of miniaturized microwave components. Unfortunately, construction of such models is challenging due to curse of dimensionality and wide range of geometry parameters that need to be included in order to make it practically useful. In this letter, a novel approach to design-oriented modeling of compact couplers is presented. Our method...
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Studying road restraint systems to develop new guidelines
PublikacjaThe paper will present a proposed approach to such work along with preliminary results of numerical studies for selected problems using road safety devices such as safety barriers on horizontal curves, the effect of kerbs on bridges or the location of obstacles within the barrier’s working width. The paper will discuss assumptions to a methodology of numerical models, calculations and automated processing of data to help with assessing...
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Heat transfer intensification by jet impingement – numerical analysis using RANS approach
PublikacjaJet impingement is a method of the heat transfer enhancement applied in the engineering systems. The idea is to generate fast-flow fluid jet which impinge on the heated (or cooled) surface, causing significantly higher heat transfer rate. Although some flat surface jet impingement cases are described in the literature, the validated data is still limited. The reason is coming from the fact, that these flows are hydrodynamically...
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Detection of People Swimming in Water Reservoirs with the Use of Multimodal Imaging and Machine Learning
PublikacjaEvery year in many countries, there are fatal unintentional drownings in different water reservoirs like swimming pools, lakes, seas, or oceans. The existing threats of this type require creating a method that could automatically supervise such places to increase the safety of bathers. This work aimed to create methods and prototype solutions for detecting people bathing in water reservoirs using a multimodal imaging system and...
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Improving the Quality of Magnetic Signature Reproduction by Increasing Flexibility of Multi-Dipole Model Structure and Enriching Measurement Information
PublikacjaThe paper presents the construction of a multi-dipole model that allows reproducing magneticsignatures of ferromagnetic objects. The virtual object used in the paper is an ellipsoid, which is the sourceof synthetic data. To make the situation more realistic, noise is added to the synthetic data. Two significantimprovements compared to previous work are presented. Three-axial magnetometers are introduced insteadof uniaxial magnetometers....