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The activity of fused-iron catalyst doped with lithium oxide for ammonia synthesis
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Effect of Cobalt on the Activity of CuO/CeO2 Catalyst for the Selective Oxidation of CO
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Noble metal-modified titania with visible-light activity for the decomposition of microorganisms
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Artificial Neural Networks for Prediction of Antibacterial Activity in Series of Imidazole Derivatives
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Evaluation of the Anti-Shigellosis Activity of Dietary Isothiocyanates in Galleria mellonella Larvae
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Counter-ion effect on antistaphylococcal activity and cytotoxicity of selected antimicrobial peptides
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Anticandidal Activity of Omiganan and Its Retro Analog Alone and in Combination with Fluconazole
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Assessment of Life Quality, Stress and Physical Activity Among Patients with Psoriasis
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The Novel Quantitative Assay for Measuring the Antibiofilm Activity of Volatile Compounds (AntiBioVol)
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Synthesis and Biological Activity of Strongly Fluorescent Tricyclic Analogues of Acyclovir and Ganciclovir
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Fluorescent Tricyclic Analogues of Acyclovir and Ganciclovir. A Structure−Antiviral Activity Study
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The Nutritional Value and Biological Activity of Concentrated Protein Fraction of Potato Juice
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Effect of psoriasis activity and topical treatment on serum lipocalin-2 levels
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Effect of Thermal Processing on Antioxidant Activity and Cytotoxicity of Waste Potato Juice
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Antimicrobial activity of 5-arylidene aromatic derivatives of hydantoin. Part 2
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Preliminary studies of the chemical composition and cytotoxic activity of Hottonia palustris herb
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Acetylcholinesterase inhibitors: structure-activity relationship and kinetic studies on selected flavonoids
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Towards discovering human urban activity—tactics of human spatial behavior
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Evaluation of Receptor Affinity, Analgesic Activity and Cytotoxicity of a Hybrid Peptide, AWL3020
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Screening of antimicrobial activity of aqueous extracts of selected Potentilla L. species
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Synthesisand cytotoxic activity of conjugates of muramyl and normuramyl dipeptides with batracylin derivatives
PublikacjaOpisano syntezę analogów MDP oraz nor-MDP modyfikowanych w części peptydowej batracyliną i pochodnymi batracyliny. Opracowano udoskonaloną metodę syntezy batracyliny. Zaproponowana metoda pozwala na otrzymanie BAT w skali multi-gramowej. Zsyntetyzowane analogi nie wykazały aktywności cytotoksycznej w badaniach prowadzonych w NCI (Bethesda, USA). W testach in vitro przeprowadzonych w Akademii Medycznej w Gdańsku dwa analogi redukowały...
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Synthesis and antitumor activity of conjugates of muramyldipeptide or normuramyldipeptide with hydroxyacridine/acridone derivatives
PublikacjaOpisano syntezę analogów MDP oraz nor-MDP modyfikowanych w części peptydowej pochodnymi hydroksyakrydyny/akrydonu i dwóch analogów modyfikowanych pochodnymi 1-nitro-9-hydroksyetylo(propylo)aminoakrydyny. Tylko związki zawierające pochodne 1-nitro-9-hydroksyetylo(propylo)aminoakrydyny wykazały wysoką aktywność cytotoksyczną badaną na 60 liniach ludzkich komórek nowotworowych, na nowotwór prostaty i AIDS-related lymphoma (ARL). Związek...
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Combretastatin A-4 (CA-4) and its analogues. Synthesis and biological activity
PublikacjaSpośród wielu związków przeciwnowotworowych otrzymanych w ostatnich dwóch dekadach, na szczególną uwagę zasługują te, które powodują reorganizację mikrotubul. Jedną z takich substancji jest opisana w artykule kombretastatyna A-4 (CA-4), związek który indukuje apoptozęproliferujących komórek śródbłonka naczyń guza nowotworowego. Hamuje on polimeryzację tubuliny, prowadząc do rozpadu mikrotubul. CA-4 wyizolowana została z kory wierzby...
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The effect of cabbage juices on the activity and expression of GST isozymes in HepG2 cells
PublikacjaWcześniejsze badania pokazały zdolność soków z kapusty białej do indukowania aktywności enzymów detoksykacyjnych. Prezentowane wyniki potwierdziły zdolność fitokompleksu kapusty do stymulacji aktywności enzymów z grupy GST w komórkach HepG2 - modelu ludzkiej wątroby - w szczególności izoenzymów GST-alfa i GST-mi.
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The Chemistry of Mycophenolic Acid-Synthesis and Modifictions Towards Desired Biological Activity
PublikacjaDokonano przeglądu literatury chemicznej na temat metod syntezy kwasu mykofenolowego oraz jego pochodnych, a także zależności pomiędzy ich strukturą i aktywnością biologiczną.
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Desmuramylopeptydy - struktura i aktywność biologiczna = Desmuramylpeptide - structure and biological activity
PublikacjaWśród fragmentów bakteryjnych ścian komórkowych, ktore wzbudzają duże zainteresowanie, są tak zwane desmuramylopeptydy. Są to cząsteczki nie zawierające reszty kwasu muraminowego. W niniejszym artykule opisano desmuramylopeptydy, które z uwagi na swoje właściwości farmakologiczne, takie jak stymulowanie niespecyficznej odporności przeciwbakteryjnej, aktywność przeciwwirusową i przeciwnowotworową oraz synergistyczne oddziaływanie...
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Antifungal activity of thionated analogues of nva-fmdp and lys-nva-fmdp
Publikacjaotrzymano dwa peptydy w których wiązanie amidowe łączące aminokwasy zamieniono na tioamidowe w wyniku kilkunastoetapowej syntezy chemicznej. do reakcji tionowania zastosowano odczynnik lawessona. otrzymane związki poddano badaniom aktywności z wykorzystaniem pięciu szczepów candida , w tym szczepów opornych na flukonazol. stwierdzono, ze obecniość wiązania tioamidowego znacznie obniża aktywność przeciwgrzybową testowanych związków...
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Characterization and photocatalytic activity of rare earth metal-doped titanium dioxide
PublikacjaW publikacji została przedstawiona metoda otrzymywania fotokatalizatorów na bazie TiO2 modyfikowanego erbem i iterbem. Otrzymane nanocząstki zostały scharakteryzowane za pomocą powierzchni właściwej BET, objętości porów. Zostały przedstawione widma absorpcyjne UV-Vis oraz właściwości fluorescencyjne otrzymanych nanoproszków. Dokonano również przedstawienia wyników pomiaru aktywności fotokatalitycznej pod wpływem promieniowania...
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Electrochemical Activity of Electrode Material Consisting of Porous Copper and Silica Aerogel
PublikacjaElectrochemically obtained copper was combined with silica aerogel (SiO2ag). Obtained composite (SiO2@Cu/CuxOy) was tested as an electrode in contact with LiPF6 in EC/DMC electrolyte. The electrochemical measurements showed the presence of complex redox couple activities of SiO2@Cu/CuxOy. This experiment was employed to help in understanding the carbon role used as an electric contact for silica in Li-Ion batteries and clarify...
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Titania Nanofiber Scaffolds with Enhanced Biointegration Activity—Preliminary In Vitro Studies
PublikacjaThe increasing need for novel bone replacement materials has been driving numerous studies on modifying their surface to stimulate osteogenic cells expansion and to accelerate bone tissue regeneration. The goal of the presented study was to optimize the production of titania-based bioactive materials with high porosity and defined nanostructure, which supports the cell viability and growth. We have chosen to our experiments TiO2...
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Synthesis and antiproliferative activity of new mycophenolic acid conjugates with adenosine derivatives
PublikacjaNew conjugates of mycophenolic acid (MPA) and adenosine derivatives were synthesized and assessed as potential immunosuppressants on Jurkat cell line and peripheral blood mononuclear cells (PBMC) from healthy donors. As compared to MPA, all compounds were found to be more active against Jurkat cell line. The antiproliferative activities were compared with MPA and adenosine, in both 2′,3′-O-isopropylidene protected and free hydroxyl...
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Daytime Acute Non-Visual Alerting Response in Brain Activity Occurs as a Result of Short- and Long-Wavelengths of Light
PublikacjaVery recent preliminary findings concerning the alerting capacities of light stimulus with long-wavelengths suggest the existence of neural pathways other than melatonin suppression that trigger the nonvisual response. Though the nonvisual effects of light during the daytime have not been investigated thoroughly, they are definitely worth investigating. The purpose of the present study is to enrich existing evidence by describing...
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Processing of point cloud data retrieved from terrestrial laser scanning for structural modeling by Finite Element Method
PublikacjaFinite Element Method is one most popular contemporary method of strength analysis. The method is an advanced method for solving differential equations, based on discretization, which means that area is divided into finite elements. Each finite element has a solution of the equation approximated by specific functions and performing the actual calculations only for nodes of this division. Finite Element Method is widely used in...
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An ANN-Based Method for On-Load Tap Changer Control in LV Networks with a Large Share of Photovoltaics—Comparative Analysis
PublikacjaThe paper proposes a new local method of controlling the on-load tap changer (OLTC) of a transformer to mitigate negative voltage phenomena in low-voltage (LV) networks with a high penetration of photovoltaic (PV) installations. The essence of the method is the use of the load compensation (LC) function with settings determined via artificial neural network (ANN) algorithms. The proposed method was compared with other selected...
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Regression points in non-intrusive polynomial chaos expansion method and D-optimal design
PublikacjaThe paper addresses selected issues of uncertainty quantification in the modelling of a system containing surgical mesh used in ventral hernia repair. Uncertainties in the models occur e.g. due to variability of abdominal wall properties among others. In order to include them, a non-intrusive regression-based polynomial chaos expansion method is employed. Its accuracy depends on the choice of regression points. In the study a relation...
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Mutual Interaction between Temperature and DO Set Point on AOB and NOB Activity during Shortcut Nitrification in a Sequencing Batch Reactor in Terms of Energy Consumption Optimization
PublikacjaRecently, many wastewater treatment plants (WWTPs) have had to deal with serious problems related to the restrictive requirements regarding the euent quality, as well as significant energy consumption associated with it. In this situation, mainstream deammonification and/or shortened nitrification-denitrification via nitrite (so-called “nitrite shunt”) is a new promising strategy. This study shows the mechanisms and operating conditions...
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Coastline change-detection method using remote sensing satellite observation data
PublikacjaCoastal zones are not only the fundaments for local economics based on trade, shipping and transport services, but also a source of food, energy and resources. Apart from offering diverse opportunities for recreation and tourism, coastal zones provide protection against storms and other meteorological disturbances. Environmental information is also essential because of the direct influence on a country’s maritime zones, which are...
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Influence of Selected Saccharides on the Precipitation of Calcium-Vaterite Mixtures by the CO2 Bubbling Method
PublikacjaCalcium carbonate is a compound existing in living organisms and produced for many biomedical applications. In this work, calcium carbonate was synthesized by a CO2 bubbling method using ammonia as a CO2 absorption promotor. Glucose, fructose, sucrose, and trehalose were added into the reaction mixture to modify characteristics of precipitated calcium carbonate particles. To determine the polymorphic form of produced calcium carbonate...
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Standard deviation as the optimization criterion in the OptD method and its influence on the generated DTM
PublikacjaReduction of the measurement dataset is one of the current issues related to constantly developing technologies that provide large datasets, eg. laser scanning. It could seems that presence and evolution of processors computer, increase of hard drive capacity etc. is the solution for development of such large datasets. And in fact it is, however, the “lighter” datasets are easier to work with. Additionally, reduced datasets can...
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Synthesis of N-doped TiO2 nanoparticles with enhanced photocatalytic activity for 2,4-dichlorophenol degradation and H2 production
PublikacjaNitrogen-doped titanium dioxide (N-TiO2) nanoparticles were prepared using a modified sol-gel method. The as-prepared nanoparticles were characterized by state-of-the-art techniques for their optical, structural and morphological properties. The crystallite size, surface area and bandgap energy of reference TiO2 and N-TiO2 nanoparticles were found to be 16.1 and 10.9 nm, 83.6 and 131.8 m2 g−1 and 3.23 and 2.89 eV, respectively....
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New method to monitor changes in the subarachnoid width and pial artery pulsation for physiological and clinical research
PublikacjaThere are several medical conditions associated with brain oedema such as traumatic brain injury, intoxication or tumors. Brain edema and related brain parenchyma expansion may lead to compression and subsequent injury of several brain structures. So far, the only method enabling detection and monitoring of the progress a cerebral oedema in a patient, has been monitoring of intracranial pressure (ICP) with a pressure probe inserted...
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Parallel Implementation of the Discrete Green's Function Formulation of the FDTD Method on a Multicore Central Processing Unit
PublikacjaParallel implementation of the discrete Green's function formulation of the finite-difference time-domain (DGF-FDTD) method was developed on a multicore central processing unit. DGF-FDTD avoids computations of the electromagnetic field in free-space cells and does not require domain termination by absorbing boundary conditions. Computed DGF-FDTD solutions are compatible with the FDTD grid enabling the perfect hybridization of FDTD...
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Adaptive Method for Modeling of Temporal Dependencies between Fields of Vision in Multi-Camera Surveillance Systems
PublikacjaA method of modeling the time of object transition between given pairs of cameras based on the Gaussian Mixture Model (GMM) is proposed in this article. Temporal dependencies modeling is a part of object re-identification based on the multi-camera experimental framework. The previously utilized Expectation-Maximization (EM) approach, requiring setting the number of mixtures arbitrarily as an input parameter, was extended with the...
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Estimating the uncertainty of discharge coefficient predicted for oblique side weir using Monte Carlo method
PublikacjaSide weir is a hydraulic structure, which is used in irrigation systems to divert some water from main to side channel. It is installed at the entrance of the side channel to control and measure passing water into the side channel. Many studies provided side weir water surface profile and coefficient of discharge to measure water discharge diverted into the side channel. These studies dealt with different side weir shapes (rectangular,...
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CAUSALITY IN MODELS OF THERMAL PROCESSES IN SHIP ENGINE ROOMS WITH THE USE OF BOND GRAPH (BG) METHOD
PublikacjaWith a single approach to modeling elements of different physical nature, the method of Bond Graph (BG) is particularly well suited for modeling energy systems consisting of mechanical, thermal, electrical and hydraulic elements that operate in the power system engine room. The paper refers to the earlier presented new concept of thermal process modeling using the BG method. The authors own suggestions for determining causality...
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Study of Aliphatic Polyurethanes by the Low-Field 1H NMR Relaxometry Method with the Inversion of the Integral Transformation
PublikacjaIn this paper, the distributions of the 1H nuclear magnetic resonance (NMR) spin–lattice and spin–spin relaxation times are used to characterize the mobility of different sections of macromolecules of aliphatic polyurethanes and the cross-linking density of polymer chains. The NMR relaxometry method with inversion of integral transformation is applied to study the effect of poly (ethylene glycol) and glycerol phosphate calcium...
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Diagnostic tolerances' evaluation method of the start-up exhaust temperature of a naval gas turbine
PublikacjaThe conducted investigations aimed to elaborate the method of marking diagnostic tolerances of the exhaust temperature of a gas turbine observed during engine's start-up process. The diagnostic tolerances were determined by means of statistical inference by creating the hypothesis about a normal distribution of the start-up exhaust temperature's dispersion in the initial operation moment, which was subsequently verified applying...
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Dynamically positioned ship steering making use of backstepping method and artificial neural networks
PublikacjaThe article discusses the issue of designing a dynamic ship positioning system making use of the adaptive vectorial backstepping method and RBF type arti cial neural networks. In the article, the backstepping controller is used to determine control laws and neural network weight adaptation laws. e arti cial neural network is applied at each time instant to approximate nonlinear functions containing parametric uncertainties....
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Measurements of Activity Coefficients at Infinite Dilution for Organic Solutes in the Ionic Liquids N-Ethyl- and N-Octyl-N-methylmorpholinium Bis(trifluoromethanesulfonyl)imide. A Useful Tool for Solvent Selection
PublikacjaIn recent years, many papers describing ionic liquids (IL) as promising solvents in separation techniques have been published. The conscious choice of appropriate ionic liquid as absorption media in effective extraction of selected types of analytes requires deeper understanding of the analyte−IL interactions. Therefore, intensive research is conducted to determine the values of activity coefficient at infinite dilution, which...
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Enhanced photocatalytic activity of accordion-like layered Ti3C2 (MXene) coupled with Fe-modified decahedral anatase particles exposing {1 0 1} and {0 0 1} facets
PublikacjaNew composites consisting of decahedral anatase particles exposing {001} and {101} facets coupled with accordion-like layered Ti3C2 with boosted photocatalytic activity towards phenol and carbamazepine degradation were investigated. The photocatalysts were characterized with X-ray diffraction (XRD), diffuse reflectance spectroscopy (DR/UV–Vis), Brunauer-Emmett-Teller (BET) specific surface area, Raman spectroscopy, scanning electron...