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Wyniki wyszukiwania dla: chaperone-usher pathwa
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Combination of hydrodynamic cavitation and SR-AOPs for simultaneous degradation of BTEX in water
PublikacjaHydrodynamic cavitation (HC) is an emerging technology gaining interest in water treatment for use in elimination of a wide range of organic pollutants. The energy released during cavitation phenomenon has number of applications and, particularly, it can be utilized for activation of persulfate (PS) and peroxymonosulfate (PMS). In the present study, hybrid techniques: HC combined with persulfates – HC-PS and HC-PMS were tested...
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Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
PublikacjaUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. A significant route of phase II drug metabolism is conjugation with glutathione (GSH), which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes. The aim of this work was to investigate the GSH-mediated metabolic pathway of a representative UA, C 2028. GSH supplemented incubations of C-2028 with rat, but not with human, liver...
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Bio‑derived polyurethanes obtained by non‑isocyanate route using polyol‑based bis(cyclic carbonate)s—studies on thermal decomposition behavior
PublikacjaNon-isocyanate polyurethanes (NIPUs) constitute one of the most prospective groups of eco-friendly materials based on their phosgene-free synthesis pathway. Moreover, one of the steps of their obtaining includes the use of carbon dioxide (CO 2 ), which allows for the promotion of the development of carbon dioxide capture and storage technologies. In this work, non- isocyanate polyurethanes were obtained via three-step synthesis...
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RecA Proteins from Deinococcus geothermalis and Deinococcus murrayi - Cloning, Purification and Biochemical Characterisation
PublikacjaEscherichia coli RecA plays a crucial role in recombinational processes, the induction of SOS response and mutagenic lesion bypasses. It has also been demonstrated that RecA protein is indispensable when it comes to the reassembly of shattered chromosomes in gamma-irradiated Deinococcus radiodurans, one of the most radiation-resistant organisms known. Moreover, some functional differences between E. coli and D. radiodurans RecA...
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Utilization of fuzzy rules in computer character animation
PublikacjaThe chapter presents a method for automatic enhancement of computer character animation utilizing fuzzy inference. First the user designs a prototype version of animation, with keyframes only for important poses, roughly describing the action. Then animation is enriched with new motion phases calculated by the fuzzy inference system using descriptors given by the user. Various degrees of motion fluency and naturalness are possible...
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DEPTH IMAGES FILTERING IN DISTRIBUTED STREAMING
PublikacjaIn this paper we discuss the comparison of point cloud filters focusing on their applicability for streaming optimization. For the filtering stage within a stream pipeline processing we evaluate three filters: Voxel Grid, Pass Through and Statistical Outlier Removal. For the filters we perform series of the tests aiming at evaluation of changes of point cloud size and transmitting frequency (various fps ratio). We propose a distributed...
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Things You Might Not Know about the k-Nearest Neighbors Algorithm
PublikacjaRecommender Systems aim at suggesting potentially interesting items to a user. The most common kind of Recommender Systems is Collaborative Filtering which follows an intuition that users who liked the same things in the past, are more likely to be interested in the same things in the future. One of Collaborative Filtering methods is the k Nearest Neighbors algorithm which finds k users who are the most similar to an active user...
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The influence of fuel type on heat balance of medium-speed engine
PublikacjaW artykule zaprezentowano analizę wpływu rodzaju zastosowanego paliwa na bilans cieplny silników średnioobrotowych stosowanych w energetyce stacjonarnej. Przedmiotem analizy są silniki ZS i ZI zasilane gazem ziemnym oraz silniki ZS zasilane olejem napędowym. Dodatkowo analizę uzupełniono o wyniki obliczeń wykonanych dla silników dwupaliwowych, tzn. silników, w których zapłon mieszanki paliwowo gazowej realizowany jest przez pilotażowy...
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Usability Techniques Possible to Use in Diagnostic Tools Interface Improvement
PublikacjaThe development of diagnostic tools has caused a rapid increase in the amount of information generated and presented, necessitating the use of computer displays as an interface to data presentation and the use of modern diagnostic tools. The paper presents methods for testing usability that can be used in designing and improving the quality of interfaces of modern diagnostic tools that use communication through graphical user interfaces.
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Z punktu widzenia uzytkownika.
PublikacjaW artykule przedstawiono wspólczesne podejscia stosowane w zakresie zapewnienia jakosci uzytkowej oprogramowania i uslug interaktywnych. Omowiono projektowanie zorientowane na uzytkownika (UCD - User Centred Design) jako widodacy kierunek w zapewnieniu satysfakcji uzytkownika koncowego oraz dokonano przegladu technik projektowo-ewaluacyjnych stosowanych w tym zakresie.
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Experimental study of the fuel jet combustion in high temperature and low oxygen content exhaust gases
PublikacjaPrzeprowadzono badania eksperymentalne spalania pojedynczego strumienia paliwa gazowego. Paliwo podawano współosiowo do generowanych przez konwencjonalny palnik gazowy spalin o wysokiej temperaturze i niskiej zawartości tlenu. Badano wpływ zawartości tlenu w utleniaczu na widzialność płomienia i skład produktów spalania.
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pH -Tunable equilibria in azocrown ethers with histidine moieties, Bioelectrochemistry
PublikacjaThe crown ethers with electro- and photoactive azo moieties containing substituents with mobile protons such as in the –COOH groups of histidine, show unique effect of pH switched on/off presence of the azo form. The differences observed for the electrochemical behavior of azocrown ethers with N-acetylhistidine and imidazole moieties reveal the interference of a chemical reduction pathway in strongly acidified solutions. This...
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A new division of bacterial UvrA homologues
PublikacjaThe UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted...
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Video Analytics-Based Algorithm for Monitoring Egress from Buildings
PublikacjaA concept and practical implementation of the algorithm for detecting of potentially dangerous situations of crowding in passages is presented. An example of such situation is a crush which may be caused by obstructed pedestrian pathway. Surveillance video camera signal analysis performed on line is employed in order to detect hold-ups near bottlenecks like doorways or staircases. The details of implemented algorithm which uses...
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Radio Channel Measurements in 868 MHz Off-Body Communications in a Ferry Environment
PublikacjaIn this paper, a characterization of the 868 MHz off-body radio channel in BANs is presented. Measurements were carried out in a ferry environment using a specific set-up. A method for path loss using radio distance measurements (RDMs) was developed. It allows to automate the measurements process and make it independent from the variable speed of a moving person. Based on the observed path loss as a function of distance, the obtained...
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A model of fuel combustion process in the marine reciprocating engine work space taking into account load and wear of crankshaft-piston assembly and the theory of semi-Markov processes
PublikacjaThe ar ticle analyses the operation of reciprocal internal combu stion engines, with mar ine engines u sed a s an example. The analysis takes into account types of energy conversion in the work spaces (cylinders) of these engines, loads of their crankshaft-piston assemblies, and types of fuel combustion which can take place in these spaces during engine operation. It is highlighted that the analysed time-dependent loads of marine...
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Wpływ udziału użytkownika na jakość użytkową w projektach informatycznych.
PublikacjaArtykuł przedstawia wyniki badań przeprowadzonych wśród 30 uczestników projektów informatycznych, reprezentujących różnorodne przedsiębiorstwa. Uzyskane dane zostały poddane analizie ilościowej z wykorzystaniem metody chi^2, której zadaniem było ocena stopnia korelacji występującego pomiędzy udziałem użytkowników końcowych, a jakością użytkową produktu. Wyniki badań skupiają się wokół poszukiwań rozwiązania problemu określanego...
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Circulating miRNA profiles and the risk of hemorrhagic transformation after thrombolytic treatment of acute ischemic stroke: a pilot study
PublikacjaBackground: Hemorrhagic transformation (HT) in acute ischemic stroke is likely to occur in patients treated with intravenous thrombolysis (IVT) and may lead to neurological deterioration and symptomatic intracranial hemorrhage (sICH). Despite the complex inclusion and exclusion criteria for IVT and some useful tools to stratify HT risk, sICH still occurs in approximately 6% of patients because some of the risk factors for this...
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Experience Visualizaton
PublikacjaSet of Experience Knowledge Structure (SOEKS) has proved its capability of storing substantial part of experience at a particular decision point. The management of SOEKS record is also proposed in many papers for example referring to concepts of Decisional DNA knowledge representation, that is a collection of a number of SOEKS. The aim of this paper is to focus on visualization and practical aspects of presenting gathered knowledge...
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Digital Audio Broadcasting or Webcasting: A Network Quality Perspective
PublikacjaIn recent years, many alternative technologies of delivering audio content have emerged, with different advantages and disadvantages. In this paper pros and cons of digital audio broadcasting and webcasting transmission techniques in a network quality perspective are described. A case study of user expectations with respect to currently available services is analyzed, and the perceived quality of real digital broadcasted and webcasted...
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Diagnostyka cieplno-przepływowa turbin parowych
PublikacjaDiagnostyka cieplno-przepływowa należy do diagnostyki technicznej zajmuje się ona badaniem oraz oceną przemian energetycznych. Głównym zadaniem diagnostyki cieplno-przepływowej jest utrzymanie obiektu w stanie jak ja wyższej sprawności. W referacie tym omawianym obiektem jest turbina parowa występująca w elektrowniach.
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Validating data acquired with experimental multimodal biometric system installed in bank branches
PublikacjaAn experimental system was engineered and implemented in 100 copies inside a real banking environment comprising: dynamic handwritten signature verification, face recognition, bank client voice recognition and hand vein distribution verification. The main purpose of the presented research was to analyze questionnaire responses reflecting user opinions on: comfort, ergonomics, intuitiveness and other aspects of the biometric enrollment...
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BACTERIAL INACTIVATION VIA LASER-DRIVEN GOLD NANOPARTICLE HEATING: SIMULATION AND ANALYSIS
PublikacjaThis study utilizes CFD technique to simulate the inactivation of E. coli bacteria within a microfluidic chamber, employing gold nanoparticles irradiated by a laser beam. Employing a single-phase model, the presence of bacteria is considered by treating thermal properties in the governing equations as effective, combining those of water and bacteria using established correlations from scientific literature. The conversion of light...
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A framework of open government data (OGD) e-service quality dimensions with future research agenda
PublikacjaPurpose This research paper aims to present a framework of open government data (OGD) relating to e-service quality dimensions. In addition, it provides a research agenda for the e-service delivery of OGD. Design/methodology/approach A literature review pertaining to e-service quality with special reference to e-government was delivered to deduce the key dimensions of e-service quality for OGD. Findings Five e-service quality dimensions...
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Smart Services for Improving eCommerce
PublikacjaThe level of customer support provided by the existing eCom-merce solutions assumes that the person using the functionality of theshop has sufficient knowledge to decide on the purchase transaction. Alow conversion rate indicates that customers are more likely to seekknowledge about the particular product than finalize the transaction.This is facilitated by the continuous development of customers’ digi-tal...
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POPRAWY ELASTYCZNOŚCI PRACY BLOKÓW PAROWYCH I GAZOWO-PAROWYCH PRZEZ ZASTOSOWANIE MAGAZYNU PARY
PublikacjaCelem niniejszej pracy jest krótki przegląd sposobów magazynowania energii i odniesienie się do sposobu, który byłby najdogodniejszy dla bloków zawodowych parowych i gazowo-parowych. W niniejszej pracy zaproponowano innowacyjny magazyn pary, który jest integralną częścią obiegu parowego, bądź gazowo-parowego i dzięki temu szybko odpowiada na zmiany zapotrzebowania na energię elektryczną, a zatem może usprawniać świadczenia usługi...
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Eye-tracking everywhere - software supporting disabled people in interaction with computers
PublikacjaIn this paper we present comprehensive system for communication with computer by gaze. One of the main assumptions behind this work was to provide solution that can be used with standard RGB webcam. The proposed comprehensive system included the eye tracking module and user interface for convenient gaze interaction with computer. As a result a fully functional application was developed. The average accuracy of the eye tracking...
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Synthesis and antimicrobial activity of 6-sulfo-6-deoxy-D-glucosamine and its derivatives
Publikacja6-Sulfo-6-deoxy-D-glucosamine (GlcN6S), 6-sulfo-6-deoxy-D-glucosaminitol (ADGS) and their N-acetyl and methyl ester derivatives have been synthesized and tested as inhibitors of enzymes catalyzing reactions of the UDP-GlcNAc pathway in bacteria and yeasts. GlcN6S and ADGS at micromolar concentrations inhibited glucosamine-6-phosphate (GlcN6P) synthase of microbial origin. The former was also inhibitory towards fungal GlcN6P N-acetyl...
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Micellar Route of the Synthesis of Alkyl Xylosides: An Unexpected Effect of Amphiphilic Imidazolium Ionic Liquids
PublikacjaThis manuscript presents results from the investigation on the synthesis of alkyl xylosides by the novel, very efficient and promising protocol of the Fischer synthesis from unprotected xylose and aliphatic alcohol. The use of 1-alkyl-3-methylimidazolium hydrogen sulfate ionic liquids as the catalysts with dual functionality (surfactant + acid catalyst) and micellar reaction system are the main novelty of described method. It has...
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Antifungal Activity of Homoaconitate and Homoisocitrate Analogs
PublikacjaThirteen structural analogs of two initial intermediates of the L-alpha-aminoadipate pathway of L-lysine biosynthesis in fungi have been designed and synthesized, including fluoro- and epoxy-derivatives of homoaconitate and homoisocitrate. Some of the obtainedcompounds exhibited at milimolar range moderate enzyme inhibitory properties against homoaconitase and/or homoisocitrate dehydrogenase of Candida albicans. The structural...
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Wybrane aktualne zagadnienia automatyki turbin.
PublikacjaDokonano przeglądu problematyki automatyki turbin, nawiązując do sytuacji w polskim przemyśle i elektroenergetyce. Na tym tle przedstawiono niektóre wyniki badań dotyczących sterowania tzw. układów kombinowanych turbina gazowa turbina parowa oraz tłokowy silnik spalinowy turbina gazowa, których zastosowanie rozwinęło się w ostatnich latach.
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Single chamber solid oxide fuel cell - current stage of development and prospects
PublikacjaOgniwa paliwowe należą do jednego z najbardziej wydatnych żródeł energii. W konwencjonalnych ogniwach paliwo i powietrze są dostarczane do ogniwa oddzielnie. Jednokomorowych ogniwo dziala zasilane mieszanina paliwa i powietrza. W pracy przedstawiono obecny stan i perspektywy dlaszego rozwoju jednokomorowych tlenkowych ogniw paliwowych.
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Separacja i zagopodarowanie CO2 z gazów spalinowych
PublikacjaGłównymi źródłami emisji antropogenicznego dwutlenku węgla w skali światowej są: produkcja energii elektrycznej, transport, przemysł. Jednym z zaproponowanych sposobów zmniejszenia emisji CO2 do atmosfery jest sekwestracja dwutlenku węgla. Separacja CO2 z gazów spalinowych ma sens przede wszystkim w elektrociepłowniach spalających paliwa kopalne.
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Luminescent properties of Ln3+ doped tellurite glasses containing AlF3
PublikacjaThe low-phonon energy tellurite glasses TeO2-BaO-Bi2O3 and TeO2-BaO-Bi2O3-AlF3 triply doped with Eu3+, Tb3+, Tm3+ ions in two different molar ratios were synthesized using melt-quenching technique. Their structure and luminescence properties were widely investigated by X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR) and Photoluminescence Spectroscopy (PL). The luminescence...
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Thermal Image Processing for Respiratory Estimation from Cubical Data with Expandable Depth
PublikacjaAs healthcare costs continue to rise, finding affordable and non-invasive ways to monitor vital signs is increasingly important. One of the key metrics for assessing overall health and identifying potential issues early on is respiratory rate (RR). Most of the existing methods require multiple steps that consist of image and signal processing. This might be difficult to deploy on edge devices that often do not have specialized...
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Glucosamine-6-phosphate synthase with an oligoHis insert
PublikacjaGlucosamine-6-phosphate (GlcN-6-P) synthase known also as L-Glutamine: D-fructose-6-phosphate aminotransferase (EC 2.6.1.16), catalyzes the first committed step in the amino sugar biosynthetic pathway in prokaryotic and eukaryotic organisms. The final product of this pathway is an activated precursor of numerous macromolecules containing amino sugars, including chitin and mannproteins in fungi, peptydoglican and lipopolysaccharides...
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Desensitization of glucosamine-6-phosphate synthase to inhibition by UDP-GlcNAc
PublikacjaGlucosamine-6-phosphate (GlcN-6-P) synthase, known also as L-Glutamine: D-fructose-6-phosphate amidotransferase, catalyzes the first committed step in the pathway leading to the ultimate formation of UDP-GlcNAc. The final product of this pathway is an activated precursor of numerous macromolecules containing amino sugars, including chitin and mannproteins in fungi, peptidoglycan and lipopolysaccharides in bacteria, and glycoproteins...
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Characterization of two aminotransferases from Candida albicans
PublikacjaAminoadipate aminotransferase (AmAA) is an enzyme of α-aminoadipate pathway (AAP) for l-lysine biosynthesis. AmAA may also participated in biosynthesis or degradation of aromatic amino acids and in d-tryptophan based pigment production. The AAP is unique for fungal microorganisms. Enzymes involved in this pathway have specific structures and properties. These features can be used as potential molecular markers. Enzymes catalyzing...
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An Empirical Propagation Model for Corridors in Office Buildings
PublikacjaThis paper presents an empirical propagation path loss model for corridors in office buildings. The proposed model estimates changeable character of radio signal attenuation, based on a special approach as a combination of the simple free-space model with the author’s model. The measurement stand and measurement scenario are described. The propagation path loss research have been made in corridor for different frequencies in range...
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Quality Aspects in Digital Broadcasting and Webcasting Systems: Bitrate versus Loudness
PublikacjaIn this paper the quality aspects of bitrate and loudness in digital broadcasting and webcasting systems are examined. The authors discuss a survey concerning user preferences related with processing and managing audio content. The coding efficiency of a popular audio format is analyzed in the context of storing media. An objective study on a representative group of signal samples, as well as a subjective study of the perceived...
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Uwarunkowania ekonomiczne wykorzystania silników gazowych do produkcji energii elektrycznej i ciepła
PublikacjaPrzedstawiono podstawowe przesłanki techniczne i ekonomiczne do zastosowania silników produkujących energię elektryczną i ciepło z wykorzystaniem jako paliwa sieciowego gazu ziemnego. Omówiono uwarunkowania funkcjonowania źródeł małej mocy na lokalnych rynkach energii. Przedstawiono problemy współpracy silników gazowych z systemami energetycznymi oraz uwarunkowania ekonomiczne rozwoju tych źródeł.
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Monosubstituted hydrazone β-cyclodextrin derivatives for pH-sensitive complex formation with aromatic drugs
PublikacjaA new and convenient synthetic pathway was developed to produce monosubstituted cyclodextrins with high yields. Each of the β-cyclodextrin derivatives described in this work has an aromatic substituent connected with cyclodextrin core by a pH-sensitive hydrazone linker and a carbon chain. Carbon chains differ in lengths having one or three carbon atoms. The correlation between water solubility and linker length was determined using...
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Phenotypic consequences of LYS4 gene disruption in Candida albicans
PublikacjaA BLAST search of the Candida Genome Database with the Saccharomyces cerevisiae LYS4 sequence known to encode homoaconitase (HA) revealed ORFs 19.3846 and 19.11327. Both alleles of the LYS4 gene were sequentially disrupted in Candida albicans BWP17 cells using PCR-based methodology. The null lys4Δ mutant exhibited lysine auxotrophy in minimal medium but was able to grow in the presence of L-Lys and α-aminoadipate, an intermediate...
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Characterization of metabolites in different kiwifruit varieties by NMR and fluorescence spectroscopy
PublikacjaIt is known from our previous studies that kiwifruits, which are used in common human diet, have preventive properties of coronary artery disease. This study describes a combination of 1H NMR spectroscopy, multivariate data analyses and fluorescence measurements in differentiating of some kiwifruit varieties, their quenching and antioxidant properties. A total of 41 metabolites were identified by comparing with literature data...
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Long Distance Vital Signs Monitoring with Person Identification for Smart Home Solutions
PublikacjaAbstract— Imaging photoplethysmography has already been proved to be successful in short distance (below 1m). However, most of the real-life use cases of measuring vital signs require the system to work at longer distances, to be both more reliable and convenient for the user. The possible scenarios that system designers must have in mind include monitoring of the vital signs of residents in nursing homes, disabled people, who...
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Flexible Knowledge–Vision–Integration Platform for Personal Protective Equipment Detection and Classification Using Hierarchical Convolutional Neural Networks and Active Leaning
PublikacjaThis work is part of an effort to develop of a Knowledge-Vision Integration Platform for Hazard Control (KVIP-HC) in industrial workplaces, adaptable to a wide range of industrial environments. The paper focuses on hazards resulted from the non-use of personal protective equipment (PPE). The objective is to test the capability of the platform to adapt to different industrial environments by simulating the process of randomly selecting...
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Oznaczanie zawartości rtęci w paliwach
PublikacjaRtęć jest jednym z najbardziej toksycznych oraz aktywnych chemicznie i biologicznie metali, który przejawia zmienność postaci występowania. Najistotniejszymi źródłami emisji rtęci są procesy spalania paliw kopalnych, zarówno stałych jak i płynnych. Paliwa mogą zawierać różne chemiczne formy rtęci, które charakteryzują się odmiennymi właściwościami, zarówno fizycznymi jak i chemicznymi. Z powodu wysokich poziomów zawartości rtęci...
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Metodyka tworzenia materiałów multimedialnych dla e-edukacji− propozycje autorskie
PublikacjaW artykule przedstawiono metodykę tworzenia i wykorzystania akademickich podreczników multimedialnych przeznaczonych do udostępniania w sieci. Opisana metodyka określana jest mianem UCD (User Centered Design). Sczegółowo omówiono trzy etapy procesu, a mianowicie: analizę, projektowanie i testowanie. Przedstawione przykłady szczegółowych rozwiazań funkcjonalnych i graficznych pochodzą z autorskich pdręczników stworzonych w technologii...
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Knowledge Management Challenges in Collaborative Design of a Virtual Call Centre
PublikacjaThis paper presents the analysis of knowledge management issues for an user interface consulting project relevant during the development of a Virtual Call Centre. Experiences gathered by the team of designers and team of usability consultants have been described and evaluated from the knowledge management viewpoint. A concept of a knowledge-based system, potentially supporting usability consulting in subsequent IT projects has...
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Accelerometer-based Human Activity Recognition and the Impact of the Sample Size
PublikacjaThe presented study focused on the recognition of eight user activities (e.g. walking, lying, climbing stairs) basing on the measurements from an accelerometer embedded in a mobile device. It is assumed that the device is carried in a specific location of the user’s clothing. Three types of classifiers were tested on different sizes of the samples. The influence of the time window (the duration of a single trial) on selected activities...