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The Role of Electrostatics in Enzymes: Do Biomolecular Force Fields Reflect Protein Electric Fields?
PublikacjaPreorganization of large, directionally oriented, electric fields inside protein active sites has been proposed as a crucial contributor to catalytic mechanism in many enzymes, and it may be efficiently investigated at the atomistic level with molecular dynamics simulations. Here, we evaluate the ability of the AMOEBA polarizable force field, as well as the additive Amber ff14SB and Charmm C36m models, to describe the electric...
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Achieving energy neutrality in wastewater treatment plants through energy savings and enhancing renewable energy production
PublikacjaWastewater treatment plants (WWTPs) consume high amounts of energy which is mostly purchased from the grid. During the past years, many ongoing measures have taken place to analyze the possible solutions for both reducing the energy consumption and increasing the renewable energy production in the plants. This review contains all possible aspects which may assist to move towards energy neutrality in WWTPs. The sources of energy...
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A compartment model of alveolar–capillary oxygen diffusion with ventilation–perfusion gradient and dynamics of air transport through the respiratory tract
PublikacjaThis paper presents a model of alveolar–capillary oxygen diffusion with dynamics of air transport through the respiratory tract. For this purpose electrical model representing the respiratory tract mechanics and differentia equations representing oxygen membrane diffusion are combined. Relevant thermodynamic relations describing the mass of oxygen transported into the human body are proposed as the connection between these models,...
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Drgania tarcz łożyskowych silników asynchronicznych wymuszane siłami elektromagnetycznymi
PublikacjaW silnikach dużej mocy przyczyny drgań i hałasu tarcz łożyskowych pochodzą głównie od pracy łożysk. W widmach drgań tarcz silników asynchronicznych małej mocy występują dominanty o częstotliwościach niezwiązanych w żaden sposób z pracą łożysk tocznych. Celem niniejszej rozprawy jest określenie mechanizmów wiążących drgania tarcz łożyskowych z wymuszeniami elektromagnetycznymi stojana. Przyjętymi metodami realizacji celu rozprawy...
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Klimatyzacja i wentylacja szpitalnych zespołów operacyjnych
PublikacjaUtrzymywanie czystości i higieny w obiektach ochrony zdrowia jest nieodłącznym elementem troski o zdrowie pacjentów i personelu medycznego. W szpitalu codziennie nawet kilkudziesięciu pacjentów może być poddawanych zabiegom operacyjnym, czasem skomplikowanym, trwającym długo i wymagającym dużego wysiłku od personelu medycznego i lekarzy operatorów. Podczas zabiegów inwazyjnych – szczególnie trudnych i długotrwałych – poziom emisji...
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Measuring research on radio wave propagation
PublikacjaTelecommunication connections are increasingly based on the wireless links, both fixed and mobile, carried out under different radio systems. This kind of solution has many advantages. However, the propagation medium is a factor that causes many difficulties in designing wireless networks, because of large diversity of propagation environments. Transmission loss in each environment is determined by many variables phenomena and...
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Induction of Secreted Human Immunodeficiency Virus Type 1 (HIV-1) Resistance Factors in CD4-Positive T Lymphocytes by Attenuated HIV-1 Infection
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MODEL OF MULTILEVEL STOCHASTIC ANALYSIS OF ROAD SAFETY ON REGIONAL LEVEL
PublikacjaIn this paper multilevel approach to the issue of road safety level on the road network of European regions, classified as NUTS 2 in statistical databases of the European Union, has been presented. Following the pattern of many publications on road safety it has been assumed that the risk calculated as the number of death casualties in road accidents per 100,000 inhabitants of a given region has Poisson distribution. Therefore,...
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The role of investments in economic development
PublikacjaIn the modern world, one may observe diversification of economies of given countries. Many of them, considered to be less developed,are aspiring to diminish the gap between them and well developed countries, one of such countries is Poland, which is trying hard to boots its competitive position in the worldwide market and achieve the constant and well-balanced development. It can be attained by building knowledge economy. Therefore,...
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Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli
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ppGpp-Dependent Negative Control of DNA Replication of Shiga Toxin-Converting Bacteriophages in Escherichia coli
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Biological activities of leaf extracts from selected Kalanchoe species and their relationship with bufadienolides content
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New Chalcone Derivatives Containing 2,4-Dichlorobenzenesulfonamide Moiety with Anticancer and Antioxidant Properties
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A MEASUREMENT SYSTEM FOR MONITORING CARDIOVASCULAR EVENTS IN SYNCOPE PATIENTS
PublikacjaSyncope phenomena is an abrupt and transient loss of consciousness leading to interruption of awareness of one’s surroundings and falls with risk of injury. Syncope is often followed by complete and usually rapid spontaneous recovery. It is said that half of all individuals experience syncopal event at least once during their life. The condition can occur at any age and happens in people with and without other medical problems....
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Masowe wymieranie pszczół – problem nie tylko pszczelarzy
PublikacjaPestycydy to bardzo liczna grupa różnorodnych związków chemicznych stosowanych w rolnictwie. Ze względu na swoją trwałość gromadzą się w różnych elementach środowiska i mogą występować w obszarze, na którym nigdy nie zostały użyte. Zachodzi także proces ich bioakumulacji w tkankach oraz narządach zwierząt i roślin. Stosowane w rolnictwie środki ochrony roślin (szczególnie w okresie wzmożonych zabiegów agrotechnicznych wiosną...
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CO2 EMISSION TO THE ATMOSPHERE FROM CARBONATE WATERS: THE STUDY CASE OF THE LUBLIN UPLAND AND ROZTOCZE REGIONS
PublikacjaThe concentration of carbon dioxide dissolved in water (CO2(aq)) was measured in consecutive phases of the hydrological cycle. Its potentially possible degassing from groundwaters to the atmosphere was also assessed. The research was conducted in the area of occurrence of carbonate rocks of the Lublin Upland and Roztocze (SE Poland). The results of the measurements of CO2(aq) concentration varied as follows (min-max/mean): precipitation...
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Use of LIDAR Data in the 3D/4D Analyses of the Krakow Fortress Objects
PublikacjaThe article presents partial results of studies within the framework of the international project "Cultural Heritage Through Time" (CHT2). The subject of the study were forts of the Krakow Fortress, which had been built by the Austrians between 1849-1914 in order to provide defence against the Russians. Research works were aimed at identifying architectural changes occurring in different time periods in relation to selected...
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Wielokryterialne Wspomaganie decyzji środowiskowych przy wydobywaniu węglowodorów z formacji łupkowych
PublikacjaPoszukiwanie i eksploatacja gazu z formacji łupkowych wymaga zidentyfikowania i uwzględnienia wielu czynników i uwarunkowań geologiczno-górniczych, ekonomiczno-finansowych, prawnych oraz szeroko rozumianych aspektów przestrzenno-środowiskowych. Poruszane zagadnienia prowadzą do zidentyfikowania problemów decyzyjnych, które mogą pojawiać się przy eksploatacji gazu z łupków, a które wiążą się z intensywnym korzystaniem z zasobów...
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Detection of debonding in adhesive joints using Lamb wave propagation
PublikacjaAdhesively bonded joints are widely used in many branches of industry. Mechanical degradation of this type of connections does not have significant symptoms that can be noticed during visual assessment, so non-destructive testing becomes a very important issue. The paper deals with experimental investigations of adhesively bonded steel plates with different defects. Five samples (an intact one and four with damages in the form...
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Progress in used tyres management in the european union: a review
PublikacjaThe dynamic increase in the manufacture of rubber products, particularly those used in the automobile industry, is responsible for a vast amount of wastes, mostly in the form of used tyres, of which more than 17 million tonnes are produced globally each year. The widely differing chemical compositions and the cross-linked structures of rubber in tyres are the prime reason why they are highly resistant to biodegradation, photochemical...
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Mikrostruktura kompozytów poliuretanowo-gumowych, otrzymywanych in situ z elastomerów uretanowych i recyklatów gumowych
PublikacjaW pracy przedstawiono wyniki badań dotyczące mikrostruktury nowej grupy kompozytów poliuretanowo-gumowych (KPG). Materiały kompozytowe otrzymano in situ z lanych elastomerów ure-tanowych (LEU) i różnej ilości recyklatu gumowego (RG), uzyskiwanego w wyniku kriogenicznego rozdrabniania poużytkowych opon samochodowych. Mikrostrukturę przełomów KPG zbadano przy wykorzystaniu mikroskopii optycznej (OM) oraz transmisyjnej mikroskopii...
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Kompozytowe Materiały poliuretanowo-Gumowe otrzymywane in situ z recyklatów gumowych oraz poliestrouretanów sieciowanych styrenem
PublikacjaW pracy zaprezentowano wyniki badań dotyczące nowej grupy kompozytowych materiałów poliuretanowo-gumowych, otrzymywanych przy udziale różnej ilości recyklatu gumowego, w których jako osnowę wykorzystano lane nienasycone poliestrouretany, poddawane rodnikowej kopolimeryzacji sieciującej styrenem.
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Kompozytowe materiały poliuretanowo-gumowe otrzymywane z lanych elastomerów uretanowych i recyklatów gumowych
PublikacjaW pracy prezentujemy wyniki badań dotyczących nowej grupy kompozytowych materiałów poliuretanowo-gumowych (KPG), otrzymywanych przy udziale różnej ilości recyklatu gumowego (RG), w których jako osnowę wykorzystano opracowane w Katedrze Technologii Polimerów Politechniki Gdańskiej lane nienasycone poliestrouretany (PEUR), poddawane rodnikowej kopolimeryzacji sieciującej ze styrenem. Zastosowanie PEUR umożliwiło uzyskanie nowej grupy...
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublikacjaDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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Testing sensitivity of A-type residual current devices to earth fault currents with harmonics
PublikacjaIn many applications, modern current-using equipment utilizes power electronic converters to control the consumed power and to adjust the motor speed. Such equipment is used both in industrial and domestic installations. A characteristic feature of the converters is producing distorted earth fault currents, which contain a wide spectrum of harmonics, including high-order harmonics. Nowadays, protection against electric shock in...
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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
PublikacjaPsoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association...
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The description of non-linear interactions of wave and non-wave modes in a non-adiabatic plasma flow
PublikacjaThe method of derivation of non-linear equations for interacting modes is explained and applied to a plasma's flow affected by a magnetic field. It is based on the linear projecting of the total perturbation field into specific variations of variables in individual modes of a flow. The method may be applied in many examples of fluid flows with different mechanisms of non-adiabaticity. It is of special importance in complex flows...
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Performance measurements and optimization of visualization of routes traveled in the distributed dispatcher and teleinformation system for visualization of multimedia data for the Border Guard
PublikacjaMonitoring of country maritime border is an important task of the Border Guard. This activity can be enhanced with the use of the technology enabling gathering information from distributed sources, processing of that information and its visualization. The system presented in the paper is an advancement of the previously developed distributed map data exchange system. The added functionality allows to supplement the map data with...
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Zarządzanie zapasami dla praktyków Jak mądrze redukować zapasy w systemie KANBAN I MRP
PublikacjaDążenie do redukcji zapasów jest naturalnym trendem wszystkich przedsiębiorstw dbających o dostęp do tzw. wolnej gotówki. 11 lat prowadzonych przeze mnie obserwacji w toku realizowanych kilkuset projektów wskazuje, że tylko ok 0,5% przedsiębiorstw (w danym momencie) nie zajmuje się pracą nad obniżeniem zapasów. Jak ta redukcja zapasów zazwyczaj się odbywa? Szef stawia cel swojemu zespołowi: „dziś rotacja naszego zapasu wynosi...
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Accuracy of Differential Phase Delay Estimation for GPS Spoofing Detection
PublikacjaGPS spoofing is an attack based on transmission of false signals to target receivers, in order to force the computation of incorrect time, position or velocity information. It is a threat which is recently considered with continuously growing awareness. There is a need for effective way of GPS spoofing detection. Many groups of methods are proposed in the literature. Spatial processing methods are considered to be robust in a wide...
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PCR-ELISA: inexpensive alternative to quantitative PCR
PublikacjaPCR-ELISA (polymerase chain reaction-enzyme linked immunosorbent assay), a combination of PCR and ELISA methods, has been used since late 1980s. The technique is based on specially labelled DNA fragments which are captured by specific DNA sequences and detected by antibodies. The whole procedure of PCR-ELISA is divided into three steps: DNA extraction, PCR reaction and detection by ELISA. The method has been found as very specific...
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Assessment of Alterations in Settlement Patterns of Agricultural Landscape in the Example of Kashubia in Poland
PublikacjaTraditional agricultural landscapes are heavily exposed to change due to their relatively low agricultural productivity. However, they represent cultural values of great importance in maintaining the resilience of the environment and society. Although their cultural potential is important for sustainable development, it is still insufficiently recognized. The article fills this gap by examining old farmstead buildings as a distinguishing...
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Superresolution algorithm to video surveillance system
PublikacjaAn application of a multiframe SR (superresolution) algorithm applied to video monitoring is described. The video signal generated by various types of video cameras with different parameters and signal distortions which may be very problematic for superresolution algorithms. The paper focuses on disadvantages in video signal which occur in video surveillance systems. Especially motion estimation and its influence on superresolution...
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Expert systems in assessing the construction process safety taking account of the risk of disturbances
PublikacjaThe objective of the paper is to present the issue of safety manage-ment during the construction process. Threats in the form of disturb-ances may occur in the preparatory phase, during the execution of the construction project and also during its operational use. The arti-cle presents the concept of applying the methodology based, among others, on Learning Bayesian Networks, Artificial Neural Networks and Support Vector Machine,...
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Influence of water salinity on corrosion risk - the case of the southern Baltic Sea coast.
PublikacjaWater corrosivity in Gdansk Bay, Poland, the southern part of the Baltic Sea, was investigated. The analysed region is heavily industrialized, and the coastline is very diverse. Twenty-seven test points along the coastline were selected. Water parameters such as salinity, total dissolved solids content, resistivity, conductivity, oxygenation, pH and corrosion rate were determined. The results of the investigation are presented....
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Diagnosis of damages in family buildings using neural networks
PublikacjaThe article concerns a problem of damages in family buildings, which result from traffic-induced vibrations. These vibrations arise from various causes and their size is influenced by many factors. The most important is the type of a road, type and weight of vehicles that run on the road, type and condition of the road surface, the distance from the house to the source of vibrations and many others which should be taken into account....
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Statistics with R A Handbook for Statistical Analysis with R and R-Studio
PublikacjaIf you are to perform any kind of data (statistical) analysis and use tools in the data science ecosystem, you may have seen a variety of tutorials, handbooks online (I’m not mentioning traditional bibles of statistics). Unfortunately most of them is written intentionally for specific purposes and/or target group of people and does not include many aspects, data types, difficult aspects, usually hiding them trying to solve theoretical...
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Plastic Debris in the Stomach of the Invasive Signal Crayfish Pacifastacus leniusculus from a Baltic Coastal River
PublikacjaPollution by plastic debris, widely recognized as a growing global problem [1-3] is caused by the production of synthetic polymers. Over recent years, the production of plastics has increased, while in Europe, fossil-based plastics production has decreased, and recycled plastics production has increased [4]. There are different types of plastics. Some types of plastic ingredients, applied in a wide variety of cosmetics and personal...
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Zmiany stężeń siarczanów w wodach podziemnych piętra czwartorzędowego Gdańska na Tarasie Nadmorskim = The sulphates concentration in the quaternary aquifer of the marine terrace in Gdańsk
PublikacjaDługoletnia eksploatacja wód podziemnych czwartorzędowego piętra wodonośnego na Tarasie Nadmorskim doprowadziła do zmian składu chemicznego pobieranej wody. Zmiany te można ocenić m.in. na podstawie zawartości jonu siarczanowego, uważanego za jeden ze wskaźników antropopresji. W tym celu określono naturalne i aktualne tło hydrogeochemiczne oraz porównano ich zakresy. Stwierdzono wzrost stężeń jonu siarczanowego, różny jednak na...
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Non-Isocyanate-Based Waterborne Polyurethanes
PublikacjaNon-isocyanate polyurethanes (NIPUs) are a greener alternative for the conventional polyurethanes synthesized using toxic and moisture-sensitive di- or polyisocyanates. The most often described method of NIPU synthesis involves the reaction of five-membered cyclic carbonates with amines, and resulting polymers containing primary and secondary hydroxyl groups (so they are also known as polyhydroxyurethanes), which can be further...
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Field Evaluation of High Modulus Asphalt Concrete Resistance to Low-Temperature Cracking
PublikacjaHigh-modulus asphalt concrete has numerous advantages in comparison to conventional asphalt concrete, including increased resistance to permanent deformations and increased pavement fatigue life. However, previous studies have shown that the construction of road pavements with High Modulus Asphalt Concrete (HMAC) may significantly increase the risk of low-temperature cracking. Those observations were the motivation for the research...
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Wino – uzupełnienie czy dominujący składnik portfela inwestycyjnego o minimalnym ryzyku
PublikacjaCel – Określenie struktury portfela inwestycyjnego o minimalnym ryzyku, składającego się z inwestycji na rynku win oraz z inwestycji w akcje spółek notowanych na wybranych giełdach Europy Środkowo-Wschodniej. Metodologia badania – Konstrukcja portfeli inwestycyjnych zgodnie z teorią zaproponowaną przez H.M. Markowitza, poparta badaniami literaturowymi odnoszącymi się do zagadnienia ekonomii wi-na. Wynik – Inwestycja w wino może...
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Mangiferin Affects Melanin Synthesis by an Influence on Tyrosinase: Inhibition, Mechanism of Action and Molecular Docking Studies
PublikacjaMangiferin is a strong antioxidant that presents a wide range of biological activities. The aim of this study was to evaluate, for the first time, the influence of mangiferin on tyrosinase, an enzyme responsible for melanin synthesis and the unwanted browning process of food. The research included both the kinetics and molecular interactions between tyrosinase and mangiferin. The research proved that mangiferin inhibits tyrosinase...
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Dynamic host configuration protocol for IPv6 improvements for mobile nodes
PublikacjaIn wireless networks mobile clients change their physical location, which results in changing point of attachment to the network. Such handovers introduce unwanted periods, when node does not have communication capabilities. Depending on many conditions, such events may require reconfiguration of layer 2 (e.g. IEEE 802.16) or both 2 and 3 layers (IPv6). This paper investigates delays introduced in the latter type of handover. IPv6...
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Polymer electrolytes with ionic liquids
PublikacjaSolid polymer electrolytes are solutions of salts in the macromolecular polymeric compound. Excellent process ability, flexibility, non-flammability and non-reactivity make them ideal materials for electrochemical devices. The problem in their use is limited conductivity. It increases with increasing salt concentration in the polymer, but at the same time the condition is to increase the glass transition temperature of the polymer...
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A headspace solid-phase microextraction method development and itsapplication in the determination of volatiles in honeys by gas chromatography
PublikacjaThe first part of the paper presents the detailed optimisation of all steps of the determination procedureof volatiles from Polish honeys by headspace solid-phase microextraction (HS-SPME) as the sample preparationmethod and gas chromatography/mass spectrometry (GC-MS) as the method of final determination.The methodology of semi-quantative analysis allowed the isolation and identification of volatile fractioncompounds from popular...
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Low-frequency tripping characteristics of residual current devices
PublikacjaFast development of various types of converters makes their utilization in industry and in domestic installations very common. Due to converters, an earth fault current waveform in modern circuits can be distorted or its frequency can be different than 50/60 Hz. Frequency of earth fault (residual) current influences tripping of residual current devices which are widely used in low voltage systems. This paper presents the behaviour...
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Reconstruction Methods for 3D Underwater Objects Using Point Cloud Data
PublikacjaExisting methods for visualizing underwater objects in three dimensions are usually based on displaying the imaged objects either as unorganised point sets or in the form of edges connecting the points in a trivial way. To allow the researcher to recognise more details and characteristic features of an investigated object, the visualization quality may be improved by transforming the unordered point clouds into higher order structures....
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Determination of 3,4-methylenedioxy-α-pyrrolidinobutiophenone (MDPB) in blood. A case report
PublikacjaSynthetic drugs, known as ‘‘legal highs’’, are still very popular on black market. The determination of their composition are required in courts of law and also to understand what potential users may be subjected to. The interest of new cathinones, e.g. MDPBP, is in view of psychoactive effects that they cause and that, in many cases, they are not controlled by law. The case outlined here concerns 19 years-old man, who was found...
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The influence of historical conditions on time and cost of construction project
PublikacjaConducting construction works in a building or in an area entered in the historic register is associated with the contracting authority's risk of incurring higher than planned costs of works, as well as delays in their implementation. In many cases, these deviations are completely independent of contracting authority and contractor. The aim of this article is to indicate the reasons for cost and time changes in the construction...