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The Knowledge Transfer From Headquarter to Local Subsidiaries Through Expatriates - Local Employees’ Perspective
PublicationBackground. Knowledge transfer between the HQ and subsidiary has recently been targets of increasing research interest. However, the role of expatriate managers and local staff perspective on this process has not been examined enough. Research aims. This paper has two main objectives: first to develop a conceptual framework (model) of knowledge transfer between the headquarters and local subsidiary, and second to empirically evaluate...
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Cross sections for electron collision with pyridine [C5H5N] molecule
PublicationThe absolute grand -total cross section (TCS) for electron scattering from pyridine, C5H5N, molecules has been measured at impact energies from 0.6 to 300 eV in the linear electron-transmission experiment. The obtained TCS energy dependence appears to be typical for targets of high electric-dipole moment; the cross section generally decreases with rising energy, except for the 3–20 eV range, where a broad enhancement peaked near...
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Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent
PublicationCarbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental methods were used, e.g., potentiometric, spectroscopic (ATR, UV, XRD powder,1H and13C NMR), electrochemical (cyclic voltammetry), and...
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Rewitalizacja jako zintegrowany proces budowania potencjałów wewnątrz miejskich obszarów rozwojowych na przykładzie hamburskiej strategii Skoku przez Łabę
PublicationPolityka Hamburga w ramach strategii Skok przez Łabę jest przykładem aktualnego kierunku odnowy miasta wychodzącej poza klasyczną rewitalizację. Poprawa jakości, udoskonalenie struktur miejskich, wymaga w obszarach problemowych niekonwencjonalnego podejścia zarówno w fazie wyznaczania docelowych standardów, jak i na etapie wdrażania rozwiązań. Dzielnice w widłach rzeki Łaby, lewobrzeżne strefy poportowe Hamburga, objęte zostały...
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Funkcjonowanie zespołów napędu hydraulicznego maszyn w niskich temperaturach otoczenia
PublicationW pracy przedstawiono cztery warianty klasyfikacji rozruchów oziębionego napędu hydraulicznego. Pierwsza sytuacja dotyczy zagadnienia, w którym wszystkie zespoły układu napędowego wraz z olejem mają taką samą niską temperaturę podczas rozruchu. Pozostałe warianty odnoszą się do rozruchu w warunkach szoku termicznego wywołanych zasilaniem ciepłym czynnikiem roboczym oziębionych zespołów hydraulicznych. Rozruch zespołów...
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FLUID BED COATING OF MINITABLETS AND PELLETS WITH OPTIMIZATION OF THE PROCESS BASED ON TAGUCHI METHOD
PublicationSmall particles like pellets are coated in fluid bed systems. This method can be also feasible for minitablets but the selection of optimal process parameters is complicated. The aim of the research was to optimize the coating process for minitablets and to compare the conditions required for pellets. Minimum fluidization velocities (umf) for 2.0 and 2.5 mm minitablets and 0.7-0.8 mm or 1.0-1.25 mm pellets were determined experimentally....
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Structure of the US investment company industry over the period 2000 to 2017: substitution analysis
PublicationOver the last years the investment company industry has undergone deep transformation in the majority of the most advanced economies, including the United States. Traditional investment companies, such as mutual funds, have lost their market share to innovative exchange-traded funds (ETFs). The main distinctive features of ETFs are listing and trading in their units on the stock exchanges as well as lower costs for investors. The...
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Impact of Innovative Financial Products on Financial Systems: Exchange Traded Products and the Polish Financial System
PublicationExchange Traded Products (ETPs) are one of the most recent and most rapidly developing financial products. As their assets grow they have an increasing impact on financial systems in many countries, including USA, UK or Japan. Development of ETPs is linked with many opportunities and threats for the local financial systems. Their correct assessment is becoming more difficult due to the growing complexity of the available products,...
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Assessment of the factors influencing on the formation of energy-oriented modes of electric power consumption by water-drainage installations of the mines
PublicationPurpose. Performing the analysis to determine energy-efficient modes and assess the characteristics of the main indicators of electric power consumption by mine water-drainage installations based on the developed research mathematical model. Methods. To achieve the purpose set, a methodology is used to develop the multiple multifactor correlation-regression modeling with respect to the modes of electric power consumption by electrical...
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Wino – uzupełnienie czy dominujący składnik portfela inwestycyjnego o minimalnym ryzyku
PublicationCel – Określenie struktury portfela inwestycyjnego o minimalnym ryzyku, składającego się z inwestycji na rynku win oraz z inwestycji w akcje spółek notowanych na wybranych giełdach Europy Środkowo-Wschodniej. Metodologia badania – Konstrukcja portfeli inwestycyjnych zgodnie z teorią zaproponowaną przez H.M. Markowitza, poparta badaniami literaturowymi odnoszącymi się do zagadnienia ekonomii wi-na. Wynik – Inwestycja w wino może...
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Energy Loss Coefficients ki in a Displacement Pump and Hydraulic Motor used in Hydrostatic Drives
PublicationThe article aims at defining and analysing the energy loss coefficients in design solutions of rotating displacement machines, with a piston machine as an example. The energy losses observed in these machines include mechanical loss, volumetric loss, and pressure loss. The scale and relations between these losses in different machines depend on machine design and manufacturing quality, and on operating parameters. The operating...
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Hybrid Processing by Turning and Burnishing of Machine Components
PublicationThe paper presents a method of hybrid manufacturing process of long 5 shafts and deep holes by simultaneous turning and burnishing method. The tech- 6 nological results of the research focus on the influence of the basic technological 7 parameters of this process on the surface roughness of piston rods of hydraulic 8 cylinders. Research results are presented in the graphs as well as mathematical 9 formula. Set of samples were made...
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Chemical Vapor Transport Route toward Black Phosphorus Nanobelts and Nanoribbons
PublicationChemical vapor transport (CVT) method is widely used for bulk black phosphorus (BP) fabrication. In this work, we demonstrate that CVT provides a route for the fabrication of BP nanoribbons and nanobelts. This method consists of a two-step procedure, including initial BP column growth using the CVT technique, followed by ultrasonic treatment and centrifugation. The obtained nanostructures preserve BP column dimensions, forming...
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Hedging Strategies of Derivatives Instruments for Commodity Trading Entities
PublicationHedging as an outcome of risk management arises to account several questions. Mentioned aspect of size of the hedging is one of them. Latter questioning refers to whether producer of manufacturer are willing to secure entire exposure, when the hedging should start, now or later in the future, what is the vision on market like direction of market, time of interest, magnitude of exposure, what would be the preferred instruments of...
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Chemical Vapor Transport Route toward Black Phosphorus Nanobelts and Nanoribbons
PublicationChemical vapor transport (CVT) method is widely used for bulk black phosphorus (BP) fabrication. In this work, we demonstrate that CVT provides a route for the fabrication of BP nanoribbons and nanobelts. This method consists of a two-step procedure, including initial BP column growth using the CVT technique, followed by ultrasonic treatment and centrifugation. The obtained nanostructures preserve BP column dimensions, forming...
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Stanowisko laboratoryjne do diagnostyki układów elektronicznych za pomocą mieszanej sygnałowo magistrali testującej.
PublicationPrzedstawiono stanowisko laboratoryjne do testowania układów elektronicznych z wykorzystaniem magistrali testującej mieszanej sygnałowo, zgodnej ze standardem IEEE 1149.4. Stanowisko laboratoryjne zrealizowano w oparciu o wyposażone w magistralę IEEE 1149.4 układy scalone STA400, opracowane przez firmę National Semiconductor i Logic Vision. Sterowanie magistralą odbywa się poprzez kontroler wykonany z wykorzystaniem portu równoległego...
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Stanowisko laboratoryjne do testowania analogowych układów elektronicznych z wykorzystaniem magistrali IEEE 1149.4.
PublicationPrzedstawiono stanowisko laboratoryjne do testowania analogowych układów elektronicznych z wykorzystaniem magistrali testującej mieszanej sygnałowo zgodnej ze standardem IEEE 1149.4. Stanowisko laboratoryjne zorganizowano w oparciu o pierwsze komercyjne układy wyposażone w magistralę IEEE 1149.4 - układy scalone STA400, opracowane przez firmę National Semiconductor i Logic Vision. Sterowanie magistralą odbywa się poprzez kontroler...
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Online stores' credibility: the moderating role of customers' gender and self-efficacy
PublicationThe evaluation of online stores’ credibility by customers in regard of gender and self-efficacy is presented. Two groups of attributes, usability and informational content, were characteristics of credibility. The survey involved students as representatives of the largest group of the Internet users. As shown by the results obtained, the informational content of online stores (such as recommendations) and its professionalism was...
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Pomoszcz Ministerstwa Inostrannych del Polszy Armenji, Azerbejdzżany i Gruzji = Polish Development Assistance for Armenia, Azerbaijan and Georgia
PublicationGeorgia has been one of the priority areas of development assistance of Polish Ministry of Foreign Affairs from 2004, because it plays a important role in Polish forsign policy in the framework of the Eastern Partnership. The largest amounts of development aid supporting the transformation were allocated for this country. Since founding the Eastern Partnership initiative in 2009 also Azerbaijan and Armenia have been included to...
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Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics – synthesis and properties
PublicationGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is known as a promising target for antimicrobial agents and antidiabetics. Several compounds of natural or synthetic origin have been identified as inhibitors of this enzyme. This set comprises highly selective L-glutamine, amino sugar phosphate or transition state intermediate cis-enolamine analogues. Relatively low antimicrobial activity of these inhibitors, poorly penetrating...
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Modelling of acoustic backscattering by southern Baltic herring
PublicationAssessment of Baltic herring abundance can be carried out using acoustic techniques. Analysis of the relationship between the Baltic herring individual target strength, TS, and the total fish length, L, important for the acoustic assessment, showed the relationship to be dependent on the location of the study area. This finding motivated a detailed analysis of the relationship for the herring occurring in the southern Baltic...
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Towards Synthetic and Balanced Digital Government Benchmarking
PublicationReliable benchmarking is essential for effective management of the government digitalization efforts. Existing benchmarking instruments generally fail to support this target. One problem is the diversity of instruments, resulting in a split image of digital progress and adding ambiguity to policy decisions. Another problem is disconnect in assessing progress between digital and traditional “analog” governance, lending support to...
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Recent progress in the development of steroid sulfatase inhibitors – examples of the novel and most promising compounds from the last decade
PublicationThe purpose of this review article is to provide an overview of recent achievements in the synthesis of novel steroid sulfatase (STS) inhibitors. STS is a crucial enzyme in the biosynthesis of active hormones (including estrogens and androgens) and, therefore, represents an extremely attractive molecular target for the development of hormone-dependent cancer therapies. The inhibition of STS may effectively reduce the availability...
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Dynamic tests of composite footbridge segment – experimental and numerical studies
PublicationExperimental dynamic tests and numerical simulations of a 3 meters long segment of a footbridge made of polymer composites are presented in the paper. The span-length is reduced, however dimensions of cross-section are the same as the target footbridge. The segment structure is made of sandwich panels, which consist of fibre reinforced polymer (GFRP) laminates (skins) and a PET foam (core). The first part of the paper contains...
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Survey of Methodologies, Approaches, and Challenges in Parallel Programming Using High-Performance Computing Systems
PublicationThis paper provides a review of contemporary methodologies and APIs for parallel programming, with representative technologies selected in terms of target system type (shared memory, distributed, and hybrid), communication patterns (one-sided and two-sided), and programming abstraction level. We analyze representatives in terms of many aspects including programming model, languages, supported platforms, license, optimization goals,...
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Is sequential batch reactor an efficient technology to protect recipient against non-steroidal anti-inflammatory drugs and paracetamol in treated wastewater?
PublicationThe tested facility was a wastewater treatment plant (WWTP) in Swarzewo, where the wastewater treatment takes place in aeration chambers with activated sludge using sequential batch reactors (SBRs). The concentration of the following pharmaceuticals: ibuprofen, paracetamol, flurbiprofen, naproxen, diclofenac, and its metabolites 5OH-diclofenac and 4OH-diclofenac was tested in influents and effluents. Simultaneously, the conventional...
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Evaluating Asymmetric N-Grams as Spell-Checking Mechanism
PublicationTypical approaches to string comparing marks two strings as either different or equal without taking into account any similarity measures. Being able to judge similarity is however required for spelling error corrections, as we want to find the best match for a given word. In this paper we present a bi2quadro-grams method for spelling errors correction. The method proposed uses different n-grams dimension for the source (checked)...
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The Role of a Software Product Manager in Various Business Environments
PublicationThe aim of the paper is to identify the role of the software product manager depending on the size of the company and the characteristics of the product they are working on. This has been achieved in cooperation with 15 experts from the IT industry. The companies were divided into 4 levels of size: micro-enterprises, small businesses, medium businesses and large enterprises. The characteristics of the products were divided into...
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Isolation of the GFA1 gene encoding glucosamine-6-phosphate synthase of Sporothrix schenckii and its expression in Saccharomyces cerevisiae
PublicationGlucosamine-6-phosphate synthase (GlcN-6-P synthase) is an essential enzyme involved in cell wall biogenesis that has been proposed as a strategic target for antifungal chemotherapy. Here we describe the cloning and functional characterization of Sporothrix schenckii GFA1 gene which was isolated from a genomic library of the fungus. The gene encodes a predicted protein of 708 amino acids that is homologous to GlcN-6-P synthases...
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A new assay based on terminal restriction fragment length polymorphism of homocitrate synthase gene fragments for Candida species identification
PublicationCandida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species specific differentiation of the Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new application of terminal restriction fragment length polymorphism (t-RFLP) method in molecular identification...
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Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors
PublicationSteroid sulfatase (STS) is responsible for the hydrolysis of biologically inactive sulfated steroids into their active un-sulfated forms and promotes the growth of various hormone-dependent cancers (e.g., breast cancer). Therefore, the STS enzyme is a promising therapeutic target for the treatment of steroid-sensitive cancers. Herein, we report the synthesis and biological evaluation of sulfamate analogs as potential STS inhibitors...
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The Ellenbogen's "Matter as Software" Concept for Quantum Computer Implementation: III. Selection of X@C60 Molecular Building Blocks (MBBs) for Tip-Based Nanofabrication (TBN) of Trapped Neutral Atom Quantum Computing Devices
PublicationThe selection of guest atoms X of X@C60 MBBs for TBN of trapped neutral atom quantum computing devices is reported. Assuming the all-optical quantum computing as a final target stage, the two criteria are most important: the charge q accumulated on the C60 host must be as low as possible, and the atom X must have one or more available excited states within the band falling into the low energy window of neutral C60 molecule electronic...
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Features extraction from the electrocatalytic gas sensor responses
PublicationOne of the types of gas sensors used for detection and identification of toxic-air pollutant is an electrocatalytic gas sensor. The electrocatalytic sensors are working in cyclic voltammetry mode, enable detection of various gases. Their response are in the form of I-V curves which contain information about the type and the concentration of measured volatile compound. However,...
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Construction of glucosamine-6-phosphate synthase with an internal hexahistydyl fragment
PublicationL-Glutamine: D-fructose-6-phosphate aminotransferase (EC 2.6.1.16), known also as glucosamine-6-phosphate (GlcN-6-P) syntase, catalyzes the first committed step in the amino sugar biosynthetic pathway in prokaryotic and eukaryotic organisms. The enzyme carries out a complex reaction involving ammonia transfer and sugar phosphate isomerization. GlcN-6-P syntase is an important point of metabolic control of amino sugar biosynthesis...
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Methodology of the Morphometry Study on Baltic Herring
PublicationAcoustic techniques are used in the estimation of the abundance of Baltic herring. Investigations of the relationship between the Baltic herring individual target strength TS and the total fish length L, significant in the acoustic assessment, demonstrated its de-pendence on the study area location. It motivated the detailed analysis of the relationship between herring from the southern Baltic ICES Subdivisions 24, 25, and 26,...
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Wear estimation of current collector contact strips by analysis of a 3D scanning results
PublicationThe technical condition of current collector contact strips is very important when operational reliability of railway transportation is considered. The authors proposed a novel measurement system based on a 3D camera to register the shape and dimensions of the current collector contact strips surface. The system was installed above the railway track for tests in target ambient. During the trial operation a few dozen of contact...
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Environmental Fate of Two Psychiatric Drugs, Diazepam and Sertraline: Phototransformation and Investigation of their Photoproducts in Natural Waters
PublicationExperimental studies were conducted to investigate the photodegradation of diazepam and sertraline, two of the most frequently used psychiatric drugs, induced by xenon lamp irradiation, which overlap the sunlight spectra, and natural sunlight. Degradation kinetics was established indicating the occurrence of autocatalytic reactions. The application of liquid chromatography coupled to quadrupole time-of-flight mass spectrometry...
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Effect of strain level on the stiffness of cold recycled bituminous mixtures
PublicationCold recycling is a sustainable technology for the rehabilitation of bitumi-nous pavements. This study investigates the stiffness response of cement-bitumen treated materials (CBTM)manufactured with 80% reclaimed asphalt and treated with 2.0% Portland cement and 4.0% bitumen emulsion. Indirect tensile stiffness modulus tests were carried out to assess the strain dependence of stiffness at target horizontal deformation levels between...
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Efficient parallel algorithms in global optimization of potential energy functions for peptides, proteins, and crystals
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Improvement of machinability of Ti and its alloys using cooling-lubrication techniques: a review and future prospect
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Evaluating Industry 4.0 Implementation Challenges Using Interpretive Structural Modeling and Fuzzy Analytic Hierarchy Process
PublicationThe fourth industrial revolution known as Industry 4.0 is reshaping and evolving the way industries produce products and individuals live and work therefore, gaining massive attraction from academia, business and politics. The manufacturing industries are optimistic regarding the opportunities Industry 4.0 may offer such as, improved efficiency, productivity and customization. The present research contributes to the Industry 4.0...
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Sex contribution to average age at onset of Huntington's disease depends on the number of (CAG)n repeats
PublicationHuntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the extension of the CAG repeats in exon 1 of the HTT gene and is transmitted in a dominant manner. The present study aimed to assess whether patients’ sex, in the context of mutated and normal allele length, contributes to age on onset (AO) of HD. The study population comprised a large cohort of 3723 HD patients from the European Huntington’s Disease...
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Theoretical and Architectural Framework for Contextual Knowledge Bases
PublicationThe paper presents the approach aimed at building modularized knowledge bases in a systematic, context-aware way. The paper focuses on logical modeling of such knowledge bases, including an underlying SIM metamodel. The architecture of a comprehensive set of tools for knowledge-base systems engineering is presented. The tools enable an engineer to design, create and edit a knowledge base schema according to a novel context approach...
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c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells
PublicationUnsymmetrical bisacridines (UAs) are highly active antitumor compounds. They contain in their structure the drugs previously synthesized in our Department: C-1311 and C-1748. UAs exhibit different properties than their monomer components. They do not intercalate to dsDNA but stabilize the G-quadruplex structures, particularly those of the MYC and KRAS genes. Since MYC and KRAS are often mutated and constitutively expressed in cancer...
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Acid–Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis
PublicationUnsymmetrical bisacridines (UAs) represent a novel class of anticancer agents previously synthesized by our group. Our recent studies have demonstrated their high antitumor potential against multiple cancer cell lines and human tumor xenografts in nude mice. At the cellular level, these compounds affected 3D cancer spheroid growth and their cellular uptake was selectively modulated by quantum dots. UAs were shown to undergo metabolic...
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Implementing Sustainable Development Goals with Digital Government – Aspiration-capacity gap
PublicationSustainable Development Goals (SDGs) represent a commitment by all United Nations Member States to pursue development efforts, including ending poverty and hunger, promoting well-being and education, reducing inequalities, fostering peace, and protecting the planet. Member States and their governments are supposed to take ownership of the SDGs, strengthen the implementation means, and improve public governance as both the means...
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Efficient Simulation-Based Global Antenna Optimization Using Characteristic Point Method and Nature-Inspired Metaheuristics
PublicationAntenna structures are designed nowadays to fulfil rigorous demands, including multi-band operation, where the center frequencies need to be precisely allocated at the assumed targets while improving other features, such as impedance matching. Achieving this requires simultaneous optimization of antenna geometry parameters. When considering multimodal problems or if a reasonable initial design is not at hand, one needs to rely...
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Diffraction of a Gaussian beam in a three-dimensional smoothly inhomogeneous medium: an eikonal-based complex geometrical-optics approach
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Application of two-dimensional intensity maps in high-accuracy polarimetry
PublicationWe propose the analysis of 2D intensity contour maps which is based on the optical transmission function for the polarizer-specimen-analyzer system. A small modification of the high-accuracy universal polarimeter (HAUP) technique was used to measure the intensity maps (HAUP maps) and determine the phase retardation, linear dichroism (LD) parameters, and multiple light reflection contribution in uniaxial crystals. We have performed...
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Dual-wavelength polarimeter application in investigations of the optical activity of a langasite crystal
PublicationA method of high accuracy polarimetry, which includes optical activity measurements systematic errors, was realized with dual-wavelength polarimeter for two wavelengths of 635 and 650 nm. Simultaneous measurements with neighboring wavelengths significantly improved the data processing, by increasing the amount of data to eliminate the systematic errors. For langasite crystal La3Ga5SiO14 we measured temperature dependence of the...