Filters
total: 3574
filtered: 818
-
Catalog
Chosen catalog filters
Search results for: FILAGGRIN, EXTRACELLULAR VESICLES, CD1A
-
Virulence of Clinical Candida Isolates
PublicationThe factors enablingCandidaspp. infections are secretion of hydrolytic enzymes, adher-ence to surfaces, biofilm formation or morphological transition, and fitness attributes. The aim of thisstudy was to investigate the correlation between known extracellular virulence factors and survivalofGalleria mellonellalarvae infected with clinicalCandida. The 25 isolates were tested and the activityof proteinases among 24/24, phospholipases...
-
Implementacja odbiornika RAKE w technologii SDR (Software Defined Radio)
PublicationRóżnorodność standardów systemów radiokomunikacyjnych, w tym telefonii komórkowej i bezprzewodowej, przy dużej ruchliwości ich abonentów, powoduje, że niezbędne jest skonstruowanie wielosystemowego terminala ruchomego, mającego techniczne możliwości współpracy z systemami radiokomunikacyjnymi działającymi w różnych standardach. W ten sposób zrodziła się idea radia definiowanego programowego SDR (Software Define Radio), bazująca...
-
Symbolic multibody models for digital-twin applications
PublicationSymbolic generation of multibody systems equations of motion appeared in the 1980s. In addition to their computational advantage over their numerical counterparts, symbolic models can be very easily and straightforwardly interfaced with a wide range of software environments and hardware devices. These two features place this approach in a pole position to participate and intervene in the design of digital twins for systems such...
-
Temperature influence on tire/road noise evaluated by the drum method
PublicationAmbient air and road surface temperatures substantially affect the road vehicle noise emission. The temperature influence on tire/road noise depends mainly on tire-road combination. It is different for dense and porous pavements, for bituminous and cement ones. It differs also depending on tires. The correction procedures for temperature effect are still under consideration and preparation. Laboratory experiment was prepared to...
-
Wpływ przechyłki na zjawisko postępowania zużycia bocznego szyn kolejowych w łukach poziomych
PublicationDegradacja elementów nawierzchni kolejowej jest zagadnieniem bardzo złożonym, w które uwikłane jest wiele czynników związanych między innymi z układem geometrycznym toru kolejowego, właściwościami trybologicznymi poszczególnych elementów nawierzchni, jak również z parametrami podłoża gruntowego, a także z właściwościami samych pojazdów szynowych. W artykule omówiono jeden z powyższych problemów, tj. wpływ ukształtowania toru kolejowego...
-
Wpływ równości nawierzchni i dynamicznego oddziaływania pojazdów ciężkich na trwałość zmęczeniową nawierzchni podatnych
PublicationPodczas ruchu pojazdu obserwuje się odchylenia nacisków osi pojazdów od nacisku statycznego, co jest spowodowane nierównościami nawierzchni. Dynamiczne obciążenia pojazdów w większym stopniu wytężają konstrukcję nawierzchni drogowej. Rozkład obciążeń dynamicznych ma kształt rozkładu normalnego i jest opisywany poprzez obciążenie statyczne oraz wskaźniki dynamiczne DI lub DLC. Wraz z pogorszeniem równości i zwiększeniem prędkości...
-
Analysis of energy efficiency of suburban railway transport network
PublicationRising numbers of agglomeration residents cause increased need for people movement on daily basis. Because of congestion of local roads, air pollution and limited parking space, providing mass transit based on electric traction is reasonable. While the electric rail vehicles are considered highly efficient in themselves, they need to be analyzed as a part of a transport network, because energy consumption depends on operating conditions...
-
A picocellular UMTS/TDD overlay on GSM system for indoor environment
PublicationW pracy przedstawiono nakładkę CDMA na system GSM. Nakładka użytkuje system UMTS w trybie TDD i jest przeznaczona do funkcjonowania wewnątrz budynków w obszarze makrokomórki systemu GSM. Wyniki badań przedstawione w pracy ukazują znaczny wzrost efektywności wykorzystania tego samego pasma przez oba systemy i uzyskanie znacznej pojemności dla nakładki bez degradacji pracy systemu GSM
-
Butyrylcholinesterase signal sequence self-aggregates and enhances amyloid fibril formation in vitro
PublicationAlzheimer’s disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also accumulates in the brain Aβ plaques in AD. We have previously found that the BChE substitution in 5′UTR caused an in-frame N-terminal extension of 41 amino acids of the BChE signal peptide. The resultant variant...
-
The psychrotrophic yeast Sporobolomyces roseus LOCK 1119 as a source of a highly active aspartic protease for the in vitro production of antioxidant peptides
PublicationA psychrotrophic yeast strain producing a cold-adapted protease at low temperature was classified as Sporobolomyces roseus. In standard YPG medium, S. roseus LOCK 1119 synthesized an extracellular protease with an activity of approximately 560 U/L. Optimization of medium composition and process temperature considerably enhanced enzyme biosynthesis; an approximate 70% increase in activity (2060 U/L). The native enzyme was purified...
-
Chracteristics of anaerobic ammonium oxidation initated by anaerobic granular sludge
PublicationTwo different mixed sludge, anaerobic granular sludge(R1) and anaerobic granular sludge with mature anaerobic ammonium oxidation (ANAMMOX) sludge (R2 )were used as the inocula in two up-flow reactors to enrich anaerobic ammonia-oxidizing bacteria (AnAOB),respectively.The total nitrogen removal rate of R1 reached 74% in 99 days, while R2 remained above 70% in only 48 days.The content of extracellular polymeric substance (EPS) in...
-
Explicit solvent repulsive scaling replica exchange molecular dynamics ( RS‐REMD ) in molecular modeling of protein‐glycosaminoglycan complexes
PublicationGlycosaminoglcyans (GAGs), linear anionic periodic polysaccharides, are crucial for many biologically relevant functions in the extracellular matrix. By interacting with proteins GAGs mediate processes such as cancer development, cell proliferation and the onset of neurodegenerative diseases. Despite this eminent importance of GAGs, they still represent a limited focus for the computational community in comparison to other classes...
-
Polydopamine Biomaterials for Skin Regeneration
PublicationDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
-
Research on operational characteristics of tyres with run flat insert
PublicationThe paper describes results of research on heavy vehicle tyre with Run Flat VFI insert. The experiment has included the determination of heat generation, rolling resistanceand radial stifnessof two different tyre designes (textile and steel carcass). The results have been used for the purpose of ewalution of tyre operating characteristics. The study included research on non-inflated tyre properties. The purpose of the paper is...
-
Poroelastic Road Surface – a Promising Road Traffic Noise Abatement Solution
PublicationRoad surfaces have a direct impact on the generation of noise by rolling tyres, the main and dominant source of noise of moving vehicles, as well as may affect propagation of noise emitted by all noise sources of a vehicle. Thus there is no doubt that pavement should be considered as one of the major potential road traffic noise abatement measure. Low noise pavements of existing types may in new conditions provide up to 8 dB of...
-
Recent advances in traffic optimisation: systematic literature review of modern models, methods and algorithms
PublicationOver the past few decades, the increasing number of vehicles and imperfect road traffic management have been sources of congestion in cities and reasons for deteriorating health of its inhabitants. With the help of computer simulations, transport engineers optimise and improve the capacity of city streets. However, with an enormous number of possible simulation types, it is difficult to grasp valuable, innovative solutions which...
-
Układy napędowe pojazdów elektrycznych
PublicationW artykule omówiono nowe technologie stosowane w układach napędowych pojazdów elektrycznych. Praca zawiera zależności teorii ruchu pojazdu, nowe rozwiązania w konstrukcji silników trakcyjnych. Przedstawiono również zagadnienia układów zasilania bateryjnego i magazynów energii z superkondensatorami. Pokazano metody sterowania zapewniające optymalizacje rozdziału energii pomiędzy akumulatorami a magazynem energii. Zaprezentowano...
-
Path Loss Modelling for Location Service Applications
PublicationThe aim of this paper is the path loss modeling for the radiolocation services in radiocommunication networks, particularly in cellular networks. The main results of the measurements obtained in the physical layer of the UMTS are introduced. A new method for the utilization of the multipath propagation phenomenon to improve the estimation of the distance between the mobile station (MS) and the base station (BS) is outlined. This...
-
Implementacja pomiaru prędkości w naziemnym systemie radiolokalizacyjnym
PublicationReferat przedstawia zagadnienie określania prędkości poruszania odbiornika lokalizacyjnego w naziemnym systemie radiolokalizacyjnym pracującym w oparciu o technikę bezpośredniego rozpraszania widma DS-CDMA. W referacie zawarto opis obróbki sygnałów w celu określenia różnic częstotliwości dopplerowskich sygnałów lokalizacyjnych odbieranych w stacji ruchomej i sposób ich przeliczania na składowe wektora prędkości oraz wyniki pomiarów...
-
Oddziaływania taboru na mosty kolejowe przy zmiennych parametrach ruchu
PublicationW pracy poruszono zagadnienia związane z identyfikacją oraz modelowaniem układu dynamicznego most-pojazd ruchomy. Za element szczególnie istotny uznano czynnik obciążający. Opracowano i wdrożono metodykę identyfikacji cech dynamicznych rzeczywistego pojazdu szynowego. Eksperyment badawczy przeprowadzono dla jednostki trakcyjnej EN57, jednak nie ma żadnych ograniczeń w stosowaniu metody dla innego, konwencjonalnego taboru szynowego....
-
Analysis of soundscape recordings in close proximity to the road in changeable wather conditions
PublicationThe acoustic vehicle sensing is the least invasive type of traffic detection. Also, acoustic-based vehicle detection technology is insensitive to precipitation and can operate in low light level. Therefore, this kind of method may be used for automatic detection of the vehicle passage events. It can also be employed for measurements of a vehicle speed and the vehicle assignment to the particular category. In this paper the results...
-
Radio Link Measurement Methodology for Location Service Applications
PublicationThe aim of this paper is the methodology of measurements executed in a radio link for the realization of radiolocation services in radiocommunication networks, particularly in cellular networks. The main results of the measurements obtained in the physical layer of the universal mobile telecommunications system (UMTS) are introduced. A new method for the utilization of the multipath propagation phenomenon to improve the estimation...
-
Photoinactivation of Staphylococcus aureus using protoporphyrin IX: the role of haem-regulated transporter HrtA
PublicationLight- and photosensitiser-based antimicrobial photodynamic therapy is a very promising approach to the control of microbial infections. How the phenotypic features of a microorganism affect its response to photosensitiser-based photokilling represents an area of substantial research interest. To understand the mechanisms governing the phenomenon of a strain-dependent response to photodynamic inactivation (PDI), we analysed the...
-
Mine counter vehicles for Baltic navy. W: [CD-ROM] Conference proceedings. UDT EUROPE 2002. Undersea Defence Technology Conference and Exhibition. La Spezia, Italy, 18-20 June 2002. Classified Conference, La Spezia, Italy, 21 June 2002 [B.m.w.]**2002 [6 s. 3 rys.]. Pojazdy przeciwminowe dla marynarki dzialającej na Bałtyku.
PublicationW opracowaniu omówiono przeciwminowe systemy opracowane przez PolitechnikęGdańską dla potrzeb Marynarki Wojennej RP. Przedstawiono podstawowe wymaga-nia rozwiązań konstrukcyjnych i zasady użycia.
-
Influence of Escherichia coli on Expression of Selected Human Drug Addiction Genes
PublicationThe impact of enteric microflora on the expression of genes associated with cocaine and amphetamine addiction was described. Human genome-wide experiments on RNA transcripts expressed in response to three selected Escherichia coli strains allowed for significant alteration (p > 0.05) of the linear regression model between HT-29 RNA transcripts associated with the KEGG pathway:hsa05030:Cocaine addiction after 3 h stimulation with...
-
Segmentation of Passenger Electric Cars Market in Poland
Publication -
an intelligent image processing sensor - the algorithm and the hardware implementation
PublicationW artykule przedstawiono algorytm przeznaczony do rozpoznawania obiektów ruchomych w obrazie do celu analizy ruchu pojazdów. Algorytm został zrealizowany w układzie FPGA.Ang.: This paper describes the idea and theimplementation of the robust algorithm dedicated toextraction of moving vehicles from real-time cameraimages for the evaluation of traffic parameters, suchas the number of vehicles, their direction of movementand their...
-
Vibration of the bridge under moving singular loads - theoretical formulation and numerical solution
PublicationThe paper presents the results of the numerical analysis of a simple vehicle passing over a simply supported bridge span. The bridge is modelled by a Euler-Bernoulli beam. The vehicle is modelled as a linear, visco-elastic oscillator, moving at a constant speed. The system is described by a set of differential equations of motion and solved numerically using the Runge-Kutta algorithm. The results are compared with the solution...
-
Metody wykorzystania energii z rekuperacji w transporcie szynowym
PublicationW artykule przedstawiony został przegląd metod wykorzystania energii pochodzącej z hamowania odzyskowego. Wśród znanych i stosowanych w praktyce metod wymieniono wykorzystanie odzyskanej energii na nietrakcyjne potrzeby własne pojazdu, magazynowanie odzyskanej energii w zasobnikach (pokładowych lub stacjonarnych) i wykorzystywanie jej w razie potrzeby, transformację i zwrot odzyskanej energii do krajowej sieci zasilania, a także...
-
Application of autoencoder to traffic noise analysis
PublicationThe aim of an autoencoder neural network is to transform the input data into a lower-dimensional code and then to reconstruct the output from this code representation. Applications of autoencoders to classifying sound events in the road traffic have not been found in the literature. The presented research aims to determine whether such an unsupervised learning method may be used for deploying classification algorithms applied to...
-
Anaerobic consortia mediate Mn(IV)-dependent anaerobic oxidation of methane
PublicationManganese-dependent anaerobic oxidation of methane (Mn-AOM) is a major methane sink and vital to mitigating global warming. However, it is difficult for microorganisms to mediate electron transfer between the hardly dissolved CH4 and insoluble Mn(IV) minerals, leading to poor understanding of species mediating Mn-AOM. This study successfully enriched an anaerobic consortium mediating AOM driven by Mn-dependent respiratory growth,...
-
Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
PublicationThe antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...
-
Comparison of Tire Rolling Resistance Measuring Methods for Different Surfaces
PublicationThe rolling resistance of car tires is one of the most important parameters characterizing tires today. This resistance has a very significant contribution to the energy consumption of wheeled vehicles. The climate crisis has forced tire and car manufacturers to place great emphasis on the environmental impact of their products. Paradoxically, the development of electric vehicles has led to an even greater importance of rolling...
-
The Idea of Using Bayesian Networks in Forecasting Impact of Traffic-Induced Vibrations Transmitted through the Ground on Residential Buildings
PublicationTraffic–induced vibrations may constitute a considerable load to buildings. In this paper, vibrations transmitted through the ground caused by wheeled vehicles are considered. This phenomenon may cause cracking of plaster, cracks in load-bearing elements or even, in extreme cases, collapse of the whole structure. Measurements of vibrations of real structures are costly and laborious. Therefore, the aim of the present paper is to...
-
Development of Intelligent Road Signs with V2X Interface for Adaptive Traffic Controlling
PublicationThe objective of this paper is to present a practical project of intelligent road signs, under which a series of new products for the regulation of traffic is being created. The engineering part of the project, described in this paper, was preceded by a series of experimental studies, the results of which were described in another paper accepted for publication at the MTS-ITS conference 2019, entitled "Comparative study on the effectiveness...
-
Synthetic strategies in construction of organic low molecular-weight carrier-drug conjugates
PublicationInefficient transportation of polar metabolic inhibitors through cell membranes of eukaryotic and prokaryotic cells precludes their direct use as drug candidates in chemotherapy. One of the possible solutions to this problem is application of the ‘Trojan horse’ strategy, i.e. conjugation of an active substance with a molecular carrier of organic or inorganic nature, facilitating membrane penetration. In this work, the synthetic...
-
Propagation Loss and Interference Analysis for 5G Systems in the Context of C-ITS System Implementation
PublicationThe article presents the concept of implementing subsequent phases of services for the C-ITS system (the Cooperative Intelligent Transport Systems), based on the European Parliament resolution of March 2018. Next, the 5G systems, in the context of their possible cooperation with C-ITS systems, were discussed. Numerical propagation analysis was performed for V2V and V2I type communication based on two different propagation models....
-
Koncepcja, modelowanie i symulacja układu napędowego prototypu samochodu elektrycznego "ELV001"
PublicationAbstract: In this paper a conception, modelling and simulation tool for drive system of the prototype electric vehicle ''ELV001'' have been presented. The design and building of this vehicle have been carried out in frame of the project: ''Building a market of electric vehicle and charging infrastructure - fundamentals of energy safety''. The simulation tools are of great assistance to engineers and researchers to reduce product-development...
-
Application of road map of operating condition for estimation of fuel and electric energy consumption from city transport
PublicationThe paper presents procedure of data collecting and generation of road map of operating condition in the selected urban area. This map allows forecasting the selected vehicle operating parameters for the assumed road. The main parameters calculated using the road maps of operating conditions are: total energy spent to drive the selected vehicle, consumed fuel, travel time, average speed of travel, CO2 emissions. Presented example...
-
Mathematical modelling of the overhead contact line for the purpose of diagnostics of pantographs
PublicationThe overhead contact line (OCL) is the most effective way for supplying railway electric vehicles. The increase of the speed of the vehicles increases power consumption and requires ensuring proper cooperation of pantographs with OCL. The paper describes the novel mathematical model of the OCL system and the simulation results. The primary objective is a more accurate analysis to increase the reliability of the evaluation of monitoring...
-
Analiza czynników wpływających na prędkość pojazdów transportu zbiorowego na przykładzie Gdańska
PublicationW referacie przedstawiono istotę problemu szacowania prędkości pojazdów transportu zbiorowego w szczególności w zakresie modelowania ruchu. Przedstawiono i omówiono wyniki przeprowadzonych w maju ubiegłego roku pomiarów czasu przejazdu pojazdów transportu zbiorowego na obszarze Gdańska w ramach budowy systemu sterowania ruchem TRISTAR. Otrzymane wyniki zestawiono w celu zaprezentowania statystyki oraz zidentyfikowania czynników...
-
Biological processes modelling for MBR systems: A review of the state-of-the-art focusing on SMP and EPS
PublicationA mathematical correlation between biomass kinetic and membrane fouling can improve the understanding and spread of Membrane Bioreactor (MBR) technology, especially in solving the membrane fouling issues. On this behalf, this paper, produced by the International Water Association (IWA) Task Group on Membrane modelling and control, reviews the current state-of-the-art regarding the modelling of kinetic processes of biomass, focusing on...
-
Advances in mass spectrometry for iron speciation in plants
PublicationIron is an important nutrient essential for plants and critical for human health. The state-of-the art of methods for iron speciation in cereal grains and plant fluids is critically reviewed. Particular attention is given to the latest developments in the coupling of HPLC with the parallel ICP MS and electrospray ionization (ESI) MS/MS detection, usually QTOF MS or Q-Orbitrap MS, for the identification and quantification of iron...
-
Application of principal component and hierarchical cluster analysis in classifying defects of trolleybuses
PublicationThe failure rate of vehicles is a relevant task, which is strictly connected with the reliability of transportation systems. Methods of data analysis allow us to find similarity and differences between failure rates of several parts of trolleybuses. This paper deals with the statistic of failure of trolleybuses from the municipal transport company of Gdynia (Poland).
-
The innovative approach for using pavement as a fire prevention measure in tunnels
PublicationThe paper consists of two main parts: first presents study regarding the typically used pavement structures in tunnels and the second part: the first fire trials of the poroelastic SEPOR (Safe, Eco-friendly POroelastic Road Surface) mixture which was designed to be used among other uses in tunnels. In the first part of the paper different pavement materials, such as cement concrete, asphalt concrete, stone mastic asphalt and porous...
-
The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
PublicationMatrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...
-
Selected Aspects of Biofuels Market and the Electromobility Development in Poland: Current Trends and Forecasting Changes
PublicationThis work presents basic information associated with markets of selected alternative fuels used in transport, such as methyl esters, conventional bioethanol and lignocellulosic bioethanol, and the market of electrical vehicles. Legal conditions, which stimulate development and regulate the mode of functioning of the liquid biofuel market until 2020 are discussed, based on provisions of EU directives. Data on biofuel production...
-
Synthetic strategies in construction of organic macromolecular carrier–drug conjugates
PublicationMany metabolic inhibitors, considered potential antimicrobial or anticancer drug candidates, exhibit verylimited ability to cross the biological membranes of target cells. The restricted cellular penetration ofthose molecules is often due to their highhydrophilicity. One of the possible solutions to this problem is aconjugation of an inhibitor with a molecular organic nanocarrier. The conjugate thus formed should beable to penetrate...
-
Analysis of Crash Computation on a Basis of the Pronciple of Linear Momentum and Kinetic Energy
PublicationThe article shows the calculation of a vehicle crash with a fixed pile, modelled by the finite element method. There were compared during the crash simulations changes in kinetic energy, as well as – changes in linear momentum and its derivative, with respect to time. Calculations were made in the HyperWorks CAE software environment. The obtained results show influence of various body parts and devices of the deceleration on...
-
Multi-criterion, evolutionary and quantum decision making in complex systems
PublicationMulti-criterion, evolutionary and quantum decision making supported by the Adaptive Quantum-based Multi-criterion Evolutionary Algorithm (AQMEA) has been considered for distributed complex systems. AQMEA had been developed to the task assignment problem, and then it has been applied to underwater vehicle planning as another benchmark three-criterion optimization problem. For evaluation of a vehicle trajectory three criteria have...