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Search results for: ASH HUMAN URINE
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Human subarachnoid space width oscillations in the resting state
PublicationAbnormal cerebrospinal fluid (CSF) pulsatility has been implicated in patients suffering from various diseases, including multiple sclerosis and hypertension. CSF pulsatility results in subarachnoid space (SAS) width changes, which can be measured with near-infrared transillumination backscattering sounding (NIR-T/BSS). The aim of this study was to combine NIR-T/BSS and wavelet analysis methods to characterise the dynamics of the...
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Analysis of the influence of polystyrene microplastics and their derivatives on the DNA of human colon epithelial cells HT29 with the comet assay
PublicationWe have been using plastic for almost a century and nowadays a lot of them circulates as pollutants in the environment and still defragmenting to micro and nanoscale. The exposition through the food chain and its precise impact on human health is still not clear. In our study, we tested real food packaging after contact with food products and real thermoinsulation and environmental samples of polystyrene in different model liquids,...
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Combined Single Neuron Unit Activity and Local Field Potential Oscillations in a Human Visual Recognition Memory Task
PublicationGOAL: Activities of neuronal networks range from action potential firing of individual neurons, coordinated oscillations of local neuronal assemblies, and distributed neural populations. Here, we describe recordings using hybrid electrodes, containing both micro- and clinical macroelectrodes, to simultaneously sample both large-scale network oscillations and single neuron spiking activity in the medial temporal lobe structures...
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The influence of Nigella sativa essential oil on proliferation, activation, and apoptosis of human T lymphocytes in vitro
PublicationIn previous work, we tested the immunomodulatory effect of Nigella sativa (NS) fatty oil. Our results demonstrated that unrefined, obtained by cold pressing black cumin seed oil inhibited lymphocytes’ proliferation and induced their apoptosis in a dose-dependent manner. In this study, we examined the immunomodulatory properties of essential oil (EO) obtained from the NS seeds by hydrodistillation and its two main constituents:...
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Preferred Benchmarking Criteria for Systematic Taxonomy of Embedded Platforms (STEP) in Human System Interaction Systems
PublicationThe rate of progress in the field of Artificial Intelligence (AI) and Machine Learning (ML) has significantly increased over the past ten years and continues to accelerate. Since then, AI has made the leap from research case studies to real production ready applications. The significance of this growth cannot be undermined as it catalyzed the very nature of computing. Conventional platforms struggle to achieve greater performance...
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The effect of thermal modification of ash wood on granularity and homogeneity of sawdust in the sawing process on a sash gang saw PRW 15-M in view of its technological usefulness
PublicationPrzedstawiono wyniki analiz granulometrycznych trocin, drewna jesionowego niemodyfikowanego (Fraxinus exelsior L.) i modyfikowanego termicznie, otrzymanych w procesie przecinania drewna na pilarce ramowej wielopiłowej PRW15-M. Przecinanie drewna prowadzono dla dwu prędkości posuwu 0,36 m·min-1 oraz 1,67 m·min-1. Ziarnistośćpowstających trocin dla drewna jesionowego modyfikowanego termicznie zawierała się w przedziale od 33,5 μm...
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A Novel IoT-Perceptive Human Activity Recognition (HAR) Approach Using Multi-Head Convolutional Attention
PublicationTogether with fast advancement of the Internet of Things (IoT), smart healthcare applications and systems are equipped with increasingly more wearable sensors and mobile devices. These sensors are used not only to collect data, but also, and more importantly, to assist in daily activity tracking and analyzing of their users. Various human activity recognition (HAR) approaches are used to enhance such tracking. Most of the existing...
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Combined analysis of whole human blood parameters by Raman spectroscopy and spectral-domain low-coherence interferometry
PublicationIn this article the simultaneous investigation of blood parameters by complementary optical methods, Raman spectroscopy and spectral-domain low-coherence interferometry, is presented. Thus, the mutual relationship between chemical and physical properties may be investigated, because low-coherence interferometry measures optical properties of the investigated object, while Raman spectroscopy gives information about its molecular...
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Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
PublicationObjective: Our goal was to analyze the electrophysiological response to direct electrical stimulation (DES) systematically applied at a wide range of parameters and anatomical sites, with particular focus on neural activities associated with memory and cognition. Methods: We used a large set of intracranial EEG (iEEG) recordings with DES from 45 subjects with electrodes...
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Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin
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Simultaneous determination of Na+, K+, Ca2+, Mg2+ and Cl- in unstimulated and stimulated human saliva using all solid state multisensor platform
PublicationHuman saliva is one of the body fluids which collection method is relatively simple and non-invasive. The article is dedicated to assess concentration (activity) of Na+, K+, Ca2+, Mg2+ and Cl- in fresh, unstimulated or stimulated human saliva samples using single solid contact ion-selective electrodes with conventional reference electrode and self-made multisensor platform (MP) equipped with ion-selective membranes for Na+, K+,...
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Human Resources Management, MiBM, IDE, II st., sem zima 2022/2023 - Nowy
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Phospholipid-functionalized gold electrode for cellular membrane interface studies - interactions between DMPC bilayer and human cystatin C
PublicationThis work describes the electrochemical studies on the interactions between V57G mutant of human cystatin C (hCC V57G) and membrane bilayer immobilized on the surface of a gold electrode. The electrode was modified with 6-mercaptohexan-1-ol (MCH) and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). DMPC was used as a membrane mimetic for monitoring electrochemical changes resulting from the interactions between the functionalized...
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Validation of Hydraulic Mechanism during Blowout Trauma of Human Orbit Depending on the Method of Load Application
PublicationThe more we know about mechanisms of the human orbital blowout type of trauma, the better we will be able to prevent them in the future. As long as the buckling mechanism’s veracity is not in doubt, the hydraulic mechanism is not based on equally strong premises. To investigate the correctness of the hydraulic mechanism’s theory, two different methods of implementation of the hydraulic load to the finite element method (FEM) model...
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Involvement of human glutathione S-transferase M1-1 in the glutathione conjugation of the antitumor unsymmetrical bisacridine derivative C-2028.
Open Research DataUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. The aim of this study was to investigate the possible role of human glutathione S-transferase M1-1 (hGSTM1-1) in the glutathione (GSH) conjugation of a representative UA, C‑2028.
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Abuse or contamination? Ratio determination of clenbuterol enantiomers to distinguish between doping use and meat contamination
PublicationClenbuterol has been detected in urine of several athletes during routine doping control in the past years. Athletes claimed that the clenbuterol was ingested by eating contaminated meat. Providing analytical prove for this claim is difficult. clenbuterol consists of two enantiomers, R(-) and S(+)-clenbuterol. Currently available human and veterinary preparations were found to consist of a racemic mixture of both enantiomers. When...
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TRNA-Leu (UUR) gene haplotypes observed in canine mammary gland tumours and its deleterious effect assessment according to the comparative analysis with TRNL1 human gene
Open Research DataThe aetiology and pathogenesis of many canine tumours are likely to be similar to cancers found in humans. This study aimed to present a plausible link between changes in tRNA-Leu (UUR) gene and the carcinogenesis process in dogs with mammary gland tumours. The whole mitochondrial DNA (mtDNA) isolated from blood and tumour tissues of 13 dogs with malig-nant...
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Multifactor consciousness level assessment of participants with acquired brain injuries employing human–computer interfaces
PublicationBackground A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the...
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Surface sliding in human abdominal wall numerical models: Comparison of single-surface and multi-surface composites
PublicationDetermining mechanical properties of abdominal soft tissues requires a coupled experimental-numerical study, but first an appropriate numerical model needs to be built. Precise modeling of human abdominal wall mechanics is difficult because of its complicated multi-layer composition and large variation between specimens. There are several approaches concerning simplification of numerical models, but it is unclear how far one could...
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Nuclear Magnetic Resonance Metabolomics Reveals Qualitative and Quantitative Differences in the Composition of Human Breast Milk and Milk Formulas
PublicationCommercial formula milk (FM) constitutes the best alternative to fulfill the nutritional requirements of infants when breastfeeding is precluded. Here, we present the comparative study of polar metabolite composition of human breast milk (HBM) and seven different brands of FM by nuclear magnetic resonance spectroscopy. The results of the multivariate data analysis exposed qualitative and quantitative differences between HBM and...
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Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems
PublicationSince human-associated bacteria have been recognized as vectors in two - way gene transmission between the pathogenic and environmental populations, health hazard connected with wastewater discharge requires reevaluation. In this paper the particular attention was given to antimicrobial-resistance of Escherichia coli and enterococci isolated from wastewater and wastewater impacted environments. The obtained results showed that...
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Isolation of Bacteriocin-producing Staphylococcus spp. Strains from Human Skin Wounds, Soft Tissue Infections and Bovine Mastitis
PublicationA collection of 206 Staphylococcus spp. isolates was investigated for their ability to produce compounds exhibiting antistaphylococcal activity. This group included Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus xylosus strains recovered from bovine mastitis (n = 158) and human skin wounds and soft tissues infections (n = 48). Production of substances with antimicrobial activity was observed in six strains. Five...
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The effect of freeze-drying and storage on lysozyme activity, lactoferrin content, superoxide dismutase activity, total antioxidant capacity and fatty acid profile of freeze-dried human milk
PublicationPooled human milk samples were freeze-dried and stored for 6 weeks at a temperature of 5 C and 25 C. Freeze-drying decreased the water content of milk by 86.5%, and the obtained lyophilizate was readily soluble in water. The freeze-drying process did not affect superoxide dismutase (SOD) activity, fatty acid (FA) profile or lactoferrin (LF) content, but it decreased total antioxidant capacity (TAC) of human milk by 22.1% and induced...
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The effect of high pressure and sub-zero temperature on total antioxidant capacity and the content of vitamin C, fatty acids and secondary products of lipid oxidation in human milk
PublicationThe objective of this study was to compare of the effects of high pressure of 193 MPa at - 20°C and Low Temperature Long Time pasteurization (LTLT or holder pasteurization, 62,5°C; 30 min) on the content and composition of fatty acids (FAs), concentrations of secondary products of lipid oxidation (TBARS), the total antioxidant capacity (TAC), total vitamin C and ascorbic acid (AsA) content in human milk. It was shown that no significant...
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublicationOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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Antimicrobial Activity of Chimera Peptides Composed of Human Neutrophil Peptide 1 (HNP-1) Truncated Analogues and Bovine Lactoferrampin
PublicationThree chimera peptides composed of bovine lactoferrampin and the analogue of truncated human neutrophil peptide 1 were synthesized by the solid-phase method. In two compounds peptide chains were connected via isopeptide bond, whereas in the third one disulfide bridge served as a linker. All three chimeras displayed significantly higher antimicrobial activity than the constituent peptides as well as their equimolar mixtures. The...
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Using creative approaches for discovering biomorphic forms for appropriate human habitation in natural environments. Case study of Kashubian Lake District
PublicationThe research process consisted of studies of natural and cultural conditions of the Kashubian Lake District This is an area of exceptional natural conditions. For centuries, it has seen human habitation with respect to landscape values. Given its extensive forest cover and the lack of heterogeneity of natural conditions, the area has become an interesting inspiration for the author’s original project. The project is aimed at searching...
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Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds
PublicationBackground Epidermal progenitor cells (EPCs) have been under extensive investigation due to their increasing potential of application in medicine and biotechnology. Cultured human EPCs are used in the treatment of chronic wounds and have recently became a target for gene therapy and toxicological studies. One of the challenges in EPCs culture is to provide a high number of undifferentiated, progenitor cells displaying high viability...
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N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
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Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
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Innovative Techniques of Processing Human Milk to Preserve Key Components
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Cylindrospermopsin: Water-linked potential threat to human health in Europe
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Metal accumulation in the human uterus varies by pathology and smoking status
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A Novel Framework for Decision Support System in Human Resource Management
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Global DNA demethylation as an epigenetic marker of human brain metastases
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Proteomic Analysis of Proton Beam Irradiated Human Melanoma Cells
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The First Report on Hybrid NOTES Adjustable Gastric Banding in Human
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The influence of durable contact on human tissue on austenitic biomaterials behaviour
PublicationBadania opierają się na studium pojedynczego przypadku dwoch wkrętów ze stali austenitycznej, które były implantowane do organizmu człowieka jako element łączący złamaną kość piszczelową. Oba wkręty zostały zostały wkręcone w jednakowych warunkach, na okres 1 roku, po którym miały zostać wyjęte. Na skutek komplikacji życiowej nosiciela, wkręty te zostały usunięte dopiero podczas zabiegu po okresie 8 lat.
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Lip movement and gesture recognition for a multimodal human-computer interface
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Formaldehyde in Human Saliva as an Indication of Environmental Tobacco Smoke Exposure
PublicationSkład środowiskowego dymu tytoniowego zależy przede wszystkim od stosowanej odmiany tytoniu oraz różnorodnych dodatków wprowadzanych do tytoniu na etapie produkcji papierosów. Podczas palenia tytoniu węglowodany ulegają złożonym przemianom, w wyniku których powstają toksyczne składniki środowiskowego dymu tytoniowego, w szczególności aldehydy (formaldehyd). Celem badań było uzyskanie informacji o poziomie zawartości formaldehydu...
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The influence of air humidity on human heat stress in a hot environment
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Bonding of doxorubicin to nanosilica and human serum albumin in various media
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Cinnamon as a Useful Preventive Substance for the Care of Human and Plant Health
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Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
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The influence of substrate peptide length on human β‐tryptase specificity
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Human Obesity Is Characterized by a Selective Potentiation of Central Chemoreflex Sensitivity
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Mechanical Modelling of Human Fascia in the Problem of Ventral Hernia Repair
PublicationPraca dotyczy badań doświadczalnych tkanki ludzkiej oraz symulacji numerycznej zachowania tej tkanki. Na podstawie eksperymentu dokonuje się identyfikacji modelu materiałowego tkanki a następnie w celu wweryfikacji przeprowadza się symulacje numeryczną zachowania modelowanej struktury. Celem badań jest uzyskanie informacji przydatnych podczas leczenia przepuklin brzusznych u ludzi.
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Sex-dependent membranopathy in stored human red blood cells
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Social differentiation of the perception and human tissues donation for research purposes
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Human adenylate kinases – classification, structure, physiological and pathological importance
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