Filters
total: 9058
-
Catalog
displaying 1000 best results Help
Search results for: BREAST%20CANCER
-
Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
PublicationFungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has increased the demand for antifungals with a different mechanism of action. The present study aimed to identify antifungal compounds targeting yeast...
-
Safety enhancement using 3D multibeam sonar imaging in shallow waters areas
PublicationSonary wielowiazkowe wykorzystanee byc moga do poprawy bezpieczenstwa zeglugi na obszarach wod plytkich. Dzieki istotnej poprawie rozdzielczosci horyzontalnej i wertykalnej pomiarow zastosowane byc moga do obrazowania wod plytkich szczegolnie niebezpiecznych pod wzgledem nawigacyjnym.
-
„Wschód” Andrzeja Stasiuka [East by Andrzej Stasiuk]
Publication -
Stage I non-small-cell lung cancer: long-term results of lobectomy versus sublobar resection from the Polish National Lung Cancer Registry†
Publication -
New Unsymmetrical Bisacridine Derivatives Noncovalently Attached to Quaternary Quantum Dots Improve Cancer Therapy by Enhancing Cytotoxicity toward Cancer Cells and Protecting Normal Cells
PublicationThe use of nanoparticles for the controlled drug delivery to cells has emerged as a good alternative to traditional systemic delivery. Quantum dots (QDs) offer potentially invaluable societal benefits such as drug targeting and in vivo biomedical imaging. In contrast, QDs may also pose risks to human health and the environment under certain conditions. Here, we demonstrated that unique combination of nanocrystals core components...
-
Sensitive determination of isoprostanes in exhaled breath condensate samples with use of liquid chromatography–tandem mass spectrometry
Publication -
Application of data segmentation and segregation in alarm dedicated glass breaks detection method,based on Wavelet Transformatio
PublicationAutor opracowuje nowoczesną, dedykowaną dla systemów alarmowych, metodę bezkontaktowej detekcji zbicia szyby, bazującą na analizie sygnałów akustycznych i transformacji falkowej. Struktura badanego sygnału oraz pierwotne metody mające zastosowanie w fazie badawczej projektu przedstawione zostały we wcześniejszych publikacjach autora [1] i [2]. Ze względu na ich dużą złożoność obliczeniowe i przetwarzanie off-line nie mogły być...
-
Sensitive determination of isoprostanes in exhaled breath condensate samples with use of liquid chromatography-tandem mass spectrometry
PublicationOxidative stress is the hallmark of various inflammatory lung diseases. Increased concentrations of reactive oxygen species in the lungs are reflected by elevated concentrations of oxidative stress markers in the breath, airways, lung tissue and blood. The aim of this work was to develop a method for the fast measurement of F2 isoprostanes in exhaled breath condensate (EBC) samples using equipment which is nowadays available and...
-
Quantification of Radiation-Induced Single-Strand Breaks in Plasmid DNA using a TUNEL/ELISA-Based Assay
PublicationWprowadzono nową metodę służącą do oznaczania in vitro pojedynczych pęknięć nici DNA powstałych pod wpływem naświetlań. Porównano wyniki otrzymane z nowej metody z modelem teoretycznym. Porównano wyniki z szeroko używaną metodą elektroforezy żelowej. Pokazano, że poziom pojedynczych pęknięć powstających w niciach DNA pod wpływem promieniowania VUV jest wyższy niż zakładany na podstawie wyników otrzymywanych metodami standardowymi.
-
Application of Rock Solid Attributes for robust identyfication of glass breaks acoustic signals via wavelet transformation
PublicationWspółczesne metody detekcji zbicia szyby stosowane w systemach alarmowych, wykorzystują analizę sygnałów akustycznych (ze względu na osiągi i koszty). Często używane metody analizy bazują na detekcji kilku charakterystycznych częstotliwości, jednak nie są to metody odporne na sygnały fałszywe. Jak wskazują niektóre pozycje literatury, zastosowanie metod JTFA może być bardziej użyteczne do analizy tego rodzaju sygnałów. Aby opracować...
-
Application of Raman Spectroscopy to Evaluate the Structure Changes of Lubricating Grease Modified with Montmorillonite after Tribological Tests
Publication -
Portable exhaled breath analyzer employing fluctuation-enhanced gas sensing method in resistive gas sensors
PublicationThis paper presents a portable exhaled breath analyser, developed to detect selected diseases. The set-up employs resistive gas sensors: commercial MEMS sensors and prototype gas sensors made of WO3 gas sensing layers doped with various metal ingredients. The set-up can modulate the gas sensors by applying UV light to induce physical changes of the gas sensing layers. The sensors are placed in a tiny gas chamber of a volume...
-
International Review of Aerospace Engineering (IREASE)
Journals -
Historic Brass Society Journal
Journals -
Agricultural Research in the Arid Areas
Journals -
JOURNAL OF GREAT LAKES RESEARCH
Journals -
The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublicationThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...
-
Growth inhibition of cultured cancer cells by Ribes nigrum leaf extract
PublicationThe present article includes data on the possible selective cytotoxic effect of extract of Ribes nigrum L. growing at high Armenian landscape. For this purpose, different non-cancer (microglial BV-2 wild type (Wt), acyl-CoA oxidase 1 (ACOX1) deficient (Acox1-/-) and cancer (human colon adenocarcinoma HT29 and human breast cancer MCF7) cell lines were applied. R. nigrum leaf ethanol extract showed a growth inhibition effect towards...
-
Predictions of cervical cancer identification by photonic method combined with machine learning
PublicationCervical cancer is one of the most commonly appearing cancers, which early diagnosis is of greatest importance. Unfortunately, many diagnoses are based on subjective opinions of doctors—to date, there is no general measurement method with a calibrated standard. The problem can be solved with the measurement system being a fusion of an optoelectronic sensor and machine learning algorithm to provide reliable assistance for doctors...
-
RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
PublicationThe receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....
-
Insights into oral microbiome and colorectal cancer – on the way of searching new perspectives
PublicationMicrobiome is a keystone polymicrobial community that coexist with human body in a beneficial relationship. These microorganisms enable the human body to maintain homeostasis and take part in mechanisms of defense against infection and in the absorption of nutrients. Even though microbiome is involved in physiologic processes that are beneficial to host health, it may also cause serious detrimental issues. Additionally, it has been...
-
Metachronous adenocarcinoma in a gastric tube after radical surgery for oesophageal cancer
Publication -
The rs1447295 and DG8S737 markers on chromosome 8q24 and cancer risk in the Polish population
Publication -
A common nonsense mutation of the BLM gene and prostate cancer risk and survival
Publication -
Quality of life in long-term survivors of early stage endometrial cancer
Publication -
Clinical Implications of mTOR Expression in Papillary Thyroid Cancer—A Systematic Review
Publication -
H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
-
Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublicationW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
-
Radiation-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
Publication -
cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer
Publication -
Mixture model of NMR - its application to diagnosis and treatment of brain cancer
Publication -
Severe oxidatively damaged DNA after cisplatin treatment of cancer patients
Publication -
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
Publication -
K-ras gene mutation as an early prognostic marker of colon cancer
Publication -
Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines
Publication -
The significance of lumican expression in ovarian cancer drug-resistant cell lines
Publication -
Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
Publication -
Prognostic factors in postoperative radiotherapy for prostate cancer – tertiary center experience
Publication -
Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
Publication -
Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery
Publication -
Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression
Publication -
New data on antihypertensive drugs and risk of cancer: should we worry?
Publication -
Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
Publication -
Assestment of the anti-cancer activity of the copper complexes with imidazole and pivalato ligands
PublicationDespite the development of science and technology progress so far there have not been found effective drugs for cancer. Many coordination compounds were investigated due to their antitumor potential. The most known cis-diamminedichloroplatinum(II) is used as anti-cancer therapeutic agent. The copper complexes are the coordination compounds possessing anti-tumour properties. Their capability to kill cancer cells is mainly linked...
-
CANCER BIOLOGY & THERAPY
Journals -
Optimization of parallel implementation of UNRES package for coarse‐grained simulations to treat large proteins
PublicationWe report major algorithmic improvements of the UNRES package for physics-based coarse-grained simulations of proteins. These include (i) introduction of interaction lists to optimize computations, (ii) transforming the inertia matrix to a pentadiagonal form to reduce computing and memory requirements, (iii) removing explicit angles and dihedral angles from energy expressions and recoding the most time-consuming energy/force terms...
-
IMPLEMENTING THE QUALITY ASSURANCE SYSTEM AND ASSURING HEALTH SAFETY IN THE LIGHT OF INCREASING BREAD QUALITY
PublicationThe article presents rules, requirements, and norms for quality management and health safety assurance systems among small and medium bakeries. This group of businesses does not have the obligation of implementing or certifying specific systems. They are, however, implemented in order to increase the quality of the bread or reach a better market position. Also, the results of a 2022 study of 53 bakeries’ implementation of individual...
-
Assessment of the Influence of Road Infrastructure Parameters on the Behaviour of Drivers and Pedestrians in Pedestrian Crossing Areas
PublicationPedestrians are participants and, most likely, fatalities in every third road traffic accident in Poland. Over 30% of all fatalities on Polish roads are pedestrians. Accidents with pedestrians are very often the result of various factors related to the infrastructure and behaviour of pedestrians and drivers. The objective of the work was to assess driver and pedestrian behaviour in pedestrian crossing areas. The research also served...
-
Evaluation of corrosion inhibition of brass-118 in artificial seawater by benzotriazole using Dynamic EIS
Publication -
GIS estimated potential of rooftop PVs in urban areas - case study Wrocław (Poland)
Publication