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Synthesis, Molecular Structure, Metabolic Stability and QSAR Studies of a Novel Series of Anticancer N-Acylbenzenesulfonamides
PublicationA series of novel N-acyl-4-chloro-5-methyl-2-(R1-methylthio)benzenesulfonamides 18–47 have been synthesized by the reaction of N-[4-chloro-5-methyl-2-(R1-methylthio) benzenesulfonyl]cyanamide potassium salts with appropriate carboxylic acids. Some of them showed anticancer activity toward the human cancer cell lines MCF-7, HCT-116 and HeLa, with the growth percentages (GPs) in the range from 7% to 46%. Quantitative structure-activity relationship...
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STILL ‘FEW, SLOW AND LOW’? ON THE FEMALE DIMENSION OF TECHNOLOGY, LABOUR MARKETS AND ECONOMIC ACTIVITY: EVIDENCE FOR THE PERIOD OF 1990-2017
PublicationThe known in empirical economics question ‘Why so Few? Why so Slow? Why so Low?’ refers here to the persistently small number of women involved in innovative activities, the slowness of change in the inequalities between women and men in these fields, and women’s continuing lower rank in business and academic positions. In developing countries, women`s labour and entrepreneurial activity remains an ‘untapped resource’ for economic...
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Generation and Propagation of Nonlinear Waves in a Towing Tank
PublicationThe paper presents the results of the research focused on linear and nonlinear wave generation and propagation in a deepwater towing tank equipped with a single flap-type wavemaker of variable draft. The problem of wave generation and propagation has been theoretically formulated and solved by applying an analytical method; linear and nonlinear solutions were obtained. The linear solution has been verified experimentally. The...
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The Impact of Homogeneity of High Modulus Asphalt Concrete Layer on Low-Temperature Cracking
PublicationDuring winter season of 2012 numerous transverse cracks developed in high-modulus asphalt concrete (HMAC) base of newly constructed motorway. Pavement cracked both in transverse joint locations and in the area between them. Research which was conducted during investigation of the causes and mechanisms of cracking consisted of: field examination, laboratory testing of specimens cored out of the existing pavement, computational analyses...
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Badanie i porównanie zdolności wybranych leków i związków przeciwnowotworowych do międzyłańcuchowego sieciowania DNA mitochondrialnego i jądrowego w komórkach nowotworowych
PublicationCelem pracy było zbadanie zdolności przeciwnowotworowych związków do indukowania międzyłańcuchowych wiązań sieciujących DNA mitochondrialne w ludzkich komórkach nowotworowych oraz porównanie ze zdolnością do sieciowania DNA jądrowego. Pochodna 4-metylo-1-nitroakrydyny C-1748, Ledakrin i mitomycyna C wykazują zdolność do sieciowania mtDNA i jDNA w komórkach raka okrężnicy HCT-8 w sposób zależny od dawki; C-1748 w komórkach raka...
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Internet photogrammetry as a tool for e-learning
PublicationAlong with Internet development, there were interactive applications which allow for remote sensing and photogrammetric analysis. An example of an application that can provide Earth images and make it possible to measure distances in these images is Google Earth. The authors, who have experience from 2001-2015 argue that it is possible and it is important to create more advanced photogrammetric network applications. In this there...
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Problematyka konstrukcyjna zabytkowego obiektu przywracanego do użytkowania na przykładzie kamienicy przy ul. Staromiejskiej w Olsztynie = Structural aspects in restoring historical buildings for re-use: the case of a tenement building on Staromiejska Street in Olsztyn
PublicationThe paper discusses the issue of introducing structural changes into a historical building referring to the example of conservation work carried out in the tenement house at 6 Staromiejska in Olsztyn. Building work involved a general renovation. The paper reviews actions carried out in the restoration work, including strengthening and deepening of the foundations, introducing a post and beam system, and putting...
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Investigation of Air Quality beside a Municipal Landfill: The Fate of Malodour Compounds as a Model VOC
PublicationThis paper presents the results of an investigation on ambient air odour quality in the vicinity of a municipal landfill. The investigations were carried out during the spring–winter and the spring seasons using two types of the electronic nose instrument. The field olfactometers were employed to determine the mean odour concentration, which was from 2.1 to 32.2 ou/m3 depending on the measurement site and season of the year. In...
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Badania eksperymentalne i numeryczne zachowania się zbiorników stalowych poddanych wstrząsom górniczym i sejsmicznym
PublicationW niniejszej dysertacji opisano wyniki kompleksowych badań zachowania się zbiorników stalowych poddanych wstrząsom górniczym i umiarkowanym trzęsieniom ziemi. Badania prowadzono dla dwóch zbiorników rzeczywistych zlokalizowanych na terenie Polski. W pierwszym etapie badań przeprowadzono badania eksperymentalne na specjalnym stanowisku laboratoryjnym dla modeli doświadczalnych zbiorników. Badania prowadzono dla różnego poziomu wypełnienia...
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Identification of Optocoupler Devices with RTS Noise
PublicationThe results of noise measurements in low frequency range for CNY 17 type optocouplers are presented. The research were carried out on devices with different values of Current Transfer Ratio (CTR). The methods for identification of Random Telegraph Signal (RTS) in noise signal of optocouplers were proposed. It was found that the Noise Scattering Pattern method (NSP method) enables to identify RTS noise as non-Gaussian component...
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Investigation of Transmit and Receive Characteristics of Laboratory Model for the Parametric Echosounder
PublicationInvestigation and operation of devices based on nonlinear interaction of high-intensity waves have been carried out for several decades. However, it is still a new tool to study the properties of the water environment and especially the upper layers of the seabed. This paper describes the results of tests of the new device that is intended to be applied for sounding underwater areas. The device has been designed and built in collaboration with...
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Lung perfusion parameters in the diagnosis of diabetic pulmonary microangiopathy
PublicationThis paper presents the role of perfusion computed tomography (pCT) in the diagnosis of diabetic pulmonary microangiopathy. Our previous works have shown that perfusion parameters are useful in the diagnosis of diabetic pulmonary microangiopathy. In this article we focus on conditions that are necessary for such the diagnosis and introduce method of classification no microangiopathy vs. microangiopathy based on logistic regression....
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Standards for Quality Assurance in the European Higher Education Area versus Common Assessment Framework in education. Conflict or harmony?
PublicationThe aim of the research was to analyze the assumptions of Standards and Guidelines for Quality Assurance in the European Higher Education Area (ENQA) and the criteria of Common Assessment Framework (CAF) for the educational sector and based on that to find out the main differences and similarities (conflicts and harmony) between them. The results of the research showed that the current trends of the quality movement evolution in...
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Uncertainty analysis of measuring system for instantaneous power research
PublicationThe paper presents a metrological analysis of the measurement system used for diagnosis of induction motor bearings, based on the analysis of the instantaneous power. This system was implemented as a set of devices with dedicated software installed on a PC. A number of measurements for uncertainty estimation was carried out. The results of the measurements are presented in the paper. The results of the aforementioned analysis helped...
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Ring thruster - a preliminary optimisation study of ferrofluid seal and propeller
PublicationThe article reports the course of preliminary examination of a ferrofluid seal applied in liquid environment.A newly built research rig is described, and results of pressure tests performed for different shaft rotationsare discussed. Other studies carried out in the past only referred to the gas environment, while the presentexamination aims at finding an answer to the question whether magnetic liquids can be successfully used...
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Requirements for Residual Current Devices Intended for Electric Vehicle Charging Systems
PublicationThe properties of residual current devices have been presented from the point of view of their ability to detect a specific shape of the residual current waveform. Moreover, the standard requirements relating to residual current protection used in electric vehicle charging installations have been pointed out. The operating characteristics of the IC-CPD and RDC-DD protections, which are intended for charging electric vehicles in...
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Stability of truss with side - supports. The case of linear and rotational elastic supports
PublicationThe research is devoted to study lateral buckling of truss with linear and rotational elastic side-supports. Geometrically nonlinear analysis of example truss with linear and rotational elastic sidesupports is carried out. The limit normal force in compressed chord of the truss due to stiffness of side supports is calculated. The elastic support reaction in relation to force in compressed chordand coefficient of buckling length...
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Rearrangeable clos networks C(n,r_1,n^2-1,n,r_2) with certain restrictions for connections
PublicationW pracy została zaproponowana nowa metoda sprawdzania przestrajalności pól Closa dla połączeń jeden do wiele. W rozważaniach zakładamy grupowanie połączeń.In the article we will propose new method of checking rearrangeability of multicast Clos networks. In the literature there is no precise method for checking rearrangeability. We focused on three-stage Clos networks without any constraints about fan-out capability. We show the...
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Research on the phenomena of warming up and free cooling down the car engine
PublicationThe average cold start temperature in Europe is 9 degrees C. However, not the average is the most important for the composition of exhaust gases and associated air pollution. The most onerous for the environment are the winter starts when automotive emissions of harmful gases add up in cities with those of home heating systems. The paper presents preliminary studies of warming up and cooling down processes in various environmental conditions....
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Monitoring Salt Water Intrusion During Construction of a Road Tunnel under the Martwa Wisła River in Gdańsk
PublicationThe paper presents results of groundwater monitoring carried out during the construction of a road tunnel under the Martwa Wisła river in Gdańsk, Poland. Martwa Wisła is one of the branches of Wisła (Vistula) river, heavily influenced by storm surges and saline water inflow from the Bay of Gdańsk. Increased values of chloride concentration were observed on both sides of the river, in particular on the western side, which was caused...
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Detection of impulsive disturbances in archive audio signals
PublicationIn this paper the problem of detection of impulsive disturbances in archive audio signals is considered. It is shown that semi-causal/noncausal solutions based on joint evaluation of signal prediction errors and leave-one-out signal interpolation errors, allow one to noticeably improve detection results compared to the prediction-only based solutions. The proposed approaches are evaluated on a set of clean audio signals contaminated...
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Implementation of Business Processes in Smart Cities Technology
PublicationThe goal of the paper is to present the results of studies concerning the development of a method of implementation of business processes in Smart Cities systems. The method has been developed during studies carried out within the building of a Smart Cities system for Gdańsk, and is based on basic development project management mechanisms (drawing from best practices, and in particular from the RUP methodology) and business-oriented...
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Test loading of the longest span arch bridge in Poland
PublicationBridge structures undergo thorough examination during test loading before they come into use. The aim of the examination is to check the correctness of the working structure and construction design assumptions. Test loading on the bridge is preceded by examination specification. This paper describes computational model and test loading results carried out during examibation of the bridge over the Vistula within the bypass of Puławy...
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Strahlungslose Übertragung von Elektronenanregungsenergie bei zweidimensionalen lumineszierenden Systemen
PublicationAn expression for the photoluminescence (PhL) quantum yield of donors in two-dimensional systems as depending on the concentration ratio nD'/nA' of donors and acceptors has been obtained. In the particular case nD' ⪡ nA' the expression reduces to the form given by other authors. The obtained formula can also be applied to the description of the concentrational quenching of PhL when dimers act as acceptors. The theory has been...
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"Ash" [æ] sound then and now: an overview of the current state of knowledge
PublicationThe objective of this article is to review the existing studies on the British Received Pronunciation “ash” [æ] sound, as well as its variations outside the United Kingdom. It starts with a short analysis of sociolinguistic aspects of the Received Pronunciation accent, then it points out the most conspicuous differences between the Received Pronunciation and General American vowel systems. Then, it presents the early beginnings...
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Monoterpenes emissions from different samples of wood-based materials – laminated chipboards and medium-density fiberboards (MDF)
PublicationThe paper presents the results of studies on emission rates of monoterpenes, carried out with the use of a new type of device - Markes’ Micro-Chamber/Thermal Extractor™ (μ-CTE250). Subject of studies were different types of wood-based materials such as: laminated chipboards and medium-density fiberboards (MDF). Based on the results obtained one can conclude that the laminated chipboards may affect the indoor air quality in much...
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Co w architekturze piszczy? Dźwiękowy wymiar przestrzeni / What’s the buzz in architecture? – The sonic aspect of space
PublicationThe article presents a debate on the dividing line between architecture and the sound sciences. It sketches out the theoretical and practical aspects of space development in the context of its sonic reception. The analysis is based on examples of projects combining architecture and art in public space and their consequences for the reception of this space. The projects relate to the use of art in urban space with special emphasis...
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Sound Art and Architecture: New Horizons for Architecture and Urbanism
PublicationThe article discusses the crossroad between art and architecture. It sketches out the theoretical and practical aspects of involving art into architecture and multisensory dimensions of space. The analysis is based on examples of innovative experimental activities for architecture: educational projects such as workshops, seminars and courses, combining art and architecture, with special emphasis on sound art, and the consequences...
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Square root RC Nyquist filter of fractional delay
PublicationIn this paper we propose a discrete-time FIR (finite impulse response) filter which couples the role of square root Nyquist filter with fractional delay filter. This filter enables to substitute for a cascade of square root RC (SRRC) Nyquist filter and fractional delay filter in one device/algorithm. The aim is to compensate for transmission delay in communication system. Statistically defined performances, e.g. BER (bit error...
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Knowledge representation of motor activity of patients with Parkinson’s disease
PublicationAn approach to the knowledge representation extraction from biomedical signals analysis concerning motor activity of Parkinson disease patients is proposed in this paper. This is done utilizing accelerometers attached to their body as well as exploiting video image of their hand movements. Experiments are carried out employing artificial neural networks and support vector machine to the recognition of characteristic motor activity...
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Diagnostics of historic columns using wave propagation
PublicationThis paper presents a numerical analysis of elastic wave propagation in columns of historical buildings for diagnostics purposes. Numerical calculations were performed using the finite element method in the Abaqus software package. The analysis was carried out for three types of brick columns: a full column, a column filled with debris, and a column empty inside. The excitation was in the form of a wave packet and signals of propagating...
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The role of the human factor in the companies' innovativeness
PublicationInnovation is one of the factors enabling the development of both individual companies and entire economies. While previously the possibilities offered by technology were focused on, including information and communication technology (ICT), recently the potential of human resources has been gaining more and more attention. This capital — often underestimated — can in the right conditions and with a conducive organizational culture...
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Influence of operation of national experimental nuclear reactor on the natural environment
PublicationThis paper presents the impact of experimental nuclear reactor operations on the national environment, based on assessment reports of the radiological protection of active nuclear technology sources. Using the analysis of measurements carried out in the last 15 years, the trends are presented in selected elements of the environment on the Świerk Nuclear Centre site and its surroundings. In addition, the impact of research results...
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Wykorzystanie miar dywergencji Csiszara do oecny podobieństwa struktury ludności krajów regionu Morza Bałtyckiego
PublicationStudies of socio-economic phenomena often touch on the issues concerning similarity between demographic structures. The measures usually used in the evaluation of structure similarity or in the investigation of the extent of structural changes are functions of distance metrics of their partial indicators. The study points out the possibility of using Csiszar divergence measures (f-divergences) in the quantification of the extent...
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Anion recognition by n,n'-diarylalkanediamides
PublicationThe preparation of N,N'-diarylalkanediamides from respective aliphatic dicarboxylic acidesand 4-nitroaniline via microwave-promoted reactions is presented. The most positive effect of microwave irradiation was observed for N,N'-bis(4-nitrophenyl)butanediamide. Anion binding studies on the obtained diamides were carried out in DMSO and acetonitrile using UV-vis and 1H NMR spectroscopy. A mechanism for selective fluoride recognition...
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Experimental investigations on condensation in flow of HFE-7100 in small diameter channels
PublicationIn the paper the authors present investigations of flow condensation with the use of the HFE-7100 as a working fluid. The original and new approach to removing the heat from the channel was applied. The research was carried out using a wide-range real time observations, e.g. using infrared camera and stroboscope microphotography. This paper presents the details of experiment as well as the influence of heat and flow parameters...
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Software modules and application layer's security structure of RSMAD
PublicationThe paper discusses the software modules of Radio System for Monitoring and Acquisition of Data from Traffic Enforcement Cameras (in short RSMAD). The structure of the application layer of the system has also been analysed in details, including: purpose, structure and principles of operation of software modules constituting this system. In addition, the paper presents and discusses the structure of security of application layer...
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The Analysis of Patients' Airflow with Respect to Early Detection of Sleep Apnea
PublicationThe paper discusses the analysis of the respiratory events of sleep apnea patients. The analysis was carried out on the basis of the patient's airflow. As a result of the conducted analysis we proposed an algorithm which establishes an individual respiratory pattern for each subject. The algorithm could be implemented in the measurement - control system which manages the prosthetic device applying positive airway pressure. Its...
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Dynamic fracture of brittle shells in a space-time adaptive isogeometric phase field framework
PublicationPhase field models for fracture prediction gained popularity as the formulation does not require the specification of ad-hoc criteria and no discontinuities are inserted in the body. This work focuses on dynamic crack evolution of brittle shell structures considering large deformations. The energy contributions from in-plane and out-of-plane deformations are separately split into tensile and compressive components and the resulting...
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Study of prototype multi-pole non-salient field winding for high speed brushless synchronous generator
PublicationIn this paper a non-salient field winding for a brushless synchronous generator working with high speed in an autonomous energy generation system (e.g. airplane power grid) has been presented. A conception of a six-pole cylindrical-rotor with distributed field winding has been proposed. Comparison study of salient and prototype non-salient field winding has been carried out. Chosen simulation and measurement results of the generator...
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EXPERIMENTS AND SIMULATIONS FOR LAPAROSCOPICVENTRAL HERNIA REPAIR IMPROVEMENT
PublicationThe authors conducted a wide experimental and numerical study in order to determine effective approaches in the laparoscopic VH repair. At first the study covered identification of mechanical properties of the abdominal fascia, implants, tacks and transabdominalsutures. Basis on these data, the one and two-dimensional mathematical models were formulated and a number of numerical static and dynamic analyses were carried out. Then...
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Estimation of transmission quality in cellular systems based on indicators measured by the radio module
PublicationThe article presents a measurement stand for testing transmission quality in cellular systems such as LTE, NB-IoT, UMTS and GSM. The results of BLER and throughput measurements for various propagation conditions as well as results of quality indicators appropriate for mentioned technologies measured by commercial radio module are presented. Those measurements were utilized to analyze the possibility of estimating the transmission...
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Design Elements of Affect Aware Video Games
PublicationIn this paper issues of design and development process of affect-aware video games are presented. Several important design aspects of such games are pointed out. A concept of a middleware framework is proposed that separates the development of affect-aware video games from emotion recognition algorithms and support from input sensors. Finally, two prototype affect-aware video games are presented that conform to the presented architecture...
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Digital technologies and women's empowerment – casting the bridges
PublicationThis work briefly discusses the nexuses between digital technology development and adoption across societies, and its potential impact on overall welfare through women’s economic empowerment. In the first section it sets out the context and background. Next, Section 2 demonstrates the state of access to and the use of digital technologies across the world. Section 3 intends to trace the causal links and channels of digital technologies'...
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Enriched buckling for beam-lattice metamaterials
PublicationWe discuss two examples of beam-lattice metamaterials which show attractive mechanical properties concerning their enriched buckling. The first one considers pantographic beams and the nonlinear solution is traced out numerically on the base of a Hencky’s model and an algorithm based on Riks’ arc-length scheme. The second one concerns a beam-lattice with sliders and the nonlinear solution is discussed in analytic way and, finally,...
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Feature type and size selection for adaboost face detection algorithm
PublicationThe article presents different sets of Haar-like features defined for adaptive boosting (AdaBoost) algorithm for face detection. Apart from a simple set of pixel intensity differences between horizontally or vertically neighboring rectangles, the features based on rotated rectangles are considered. Additional parameter that limits the area on which the features are calculated is also introduced. The experiments carried out on...
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Influence and selection of basic concepts on ontology design
PublicationOntologies as entities representing individual point of view on surrounding world introduce heterogeneity to knowledge representation. Common set of core concepts can introduce similarity big enough for further interoperability between ontologies. In this paper an experiment is presented proving that despite differences in detail ontologies stay similar in regard of core concepts. During the experiments NOIA methodology enhanced...
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Reliability assessment of truss towers using Monte Carlo Method, PEM and RSM
PublicationThe paper discusses the reliability assessment of simple random truss structures using three different probabilistic methodologies: the Monte Carlo method, the Point Estimate Method and the Response Surface Method. A benchmark truss structure example is analyzed. A set of numerical calculations of critical load is performed and the results are taken as the basis of advanced probabilistic calculations. Using the samples, numerical...
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Statistical significance of displacements in heterogeneous control networks
PublicationThis paper proposes a modification of the classical process for evaluating the statistical significance of displacements in the case of heterogeneous (e.g. linear-angular) control networks established to deformation measurements and analysis. The basis for the proposed solution is the idea of local variance factors. The theoretical discussion was complemented with an example of its application on a simulated horizontal control...
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Innovative Cold-formed GEB Section under Bending
PublicationThis paper is concerned with the numerical bending capacity study of the innovative cold-formed GEB sections. Both linear buckling analysis and non-linear static analysis incorporating geometric and material nonlinearity were carried out employing a shell structural model. The magnitudes of buckling load and limit load with respect to GEB section depth and thickness were obtained. The opened cold-formed section was tested assuming...