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Antitumor Activity of Triazine Mimic Antibiotics for DNA-binding Implications (Impressive Activity in Vitro Against a Variety of Tumor Types in the NCI-60 Screen): NSC 710607 To Fight HCT-116 Human Colon Carcinoma Cell Lines in Vivo Using the Hollow Fiber Assay and Xenograft Mouse Models
PublicationPurpose Successful clinical applications of DNA-directed selective cytotoxic agents disrupt the vital replication/transcription processes and ultimately lead to cancer cell death. This study aimed to examine the growth screen of two lead triazine compounds in a number of cell lines and xenografts and to develop anticancer agents with noncovalent binding affinity bringing fewer side effects. Methods The NCI initial hollow...
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Analytical progress on symmetric geometric discord: Measurement-based upper bounds
PublicationQuantum correlations may be measured by means of the distance of the state to the subclass ofstates having well defined classical properties. In particular, a geometric measure of asymmetricdiscord [Daki´c et al., Phys. Rev. Lett. 105, 190502 (2010)] was recently defined as the Hilbert-Schmidt distance of a given two-qubit state to the closest classical-quantum (CQ) correlated state.We analyze a geometric measure of symmetric...
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The impact of mass-media campaigns on physical activity: a review of reviews through a policy lens
PublicationBackground This review of reviews aimed to: (1) summarize the evidence from published reviews on the effectiveness of mass-media campaigns to promote physical activity (PA) or PA-related determinants (intermediate psychological and proximal outcomes) and (2) to identify policy-relevant recommendations related to successful PA campaigns. Methods An extensive literature search was performed on 1 March 2021. Reviews that evaluated...
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Volatile Compound Emissions from Stereolithography Three-Dimensional Printed Cured Resin Models for Biomedical Applications
PublicationStereolithography three-dimensional printing is used increasingly in biomedical applications to create components for use in healthcare and therapy. The exposure of patients to volatile organic compounds (VOCs) emitted from cured resins represents an element of concern in such applications. Here, we investigate the biocompatibility in relation to inhalation exposure of volatile emissions of three different cured commercial resins...
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Transcriptomic landscape of blood platelets in healthy donors
PublicationBACKGROUND Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce and merit complex investigation. METHODS We sought to explore the dynamics of platelet transcriptome. Datasets from 204 healthy donors were used for the analysis of splice variants,...
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Evolving neural network as a decision support system — Controller for a game of “2048” case study
PublicationThe paper proposes an approach to designing the neuro-genetic self-learning decision support system. The system is based on neural networks being adaptively learned by evolutionary mechanism, forming an evolved neural network. Presented learning algorithm enables for a selection of the neural network structure by establishing or removing of connections between the neurons, and then for a finding the beast suited values of the network...
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Algorytmy hybrydowe optymalizacji w zastosowaniu do problemu sterowania systemami dystrybucji wody
PublicationW pracy analizowany jest problem optymalizującego zintegrowanego sterowania ilością i jakością w systemach dystrybucji wody. Proponowane decyzje i sterowania powinny zapewniać optymalizację przyjętego wskaźnika jakości, przy spełnieniu ograniczeń właściwych tej klasie systemów. Ostatecznie do rozwiązania złożonych zadań optymalizacji dynamicznej zaproponowane zostało podejście hybrydowe, wspomagające predykcyjne algorytmy sterowania...
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Organizmy modyfikowane genetycznie. Jak bardzo są one szkodliwe?
PublicationA review, with 47 refs., of the methods for genetic changes in plants and animals and their uses for prodn. of food and tech. products and for environmental protection. Some debates on hazards connected with uses of genetically modified organismus were also reported. Uprawa i wykorzystanie organizmów genetycznie modyfikowanych (GMO), szczególnie organizmów transgenicznych wywołują poważne, skrajnie kontrowersyjne emocje. przeciwnicy...
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Transition curve with smoothed curvature at its ends for railway roads
PublicationIn the paper, in view of a railway ballasted track, a new concept of transition curve of linear form of curvature along its length and smoothed extreme regions is presented. For this purpose use has been made of an original, universal method for identifying transition curves by means of differential equations. Some general curvature equations for three regions investigated have been determined to be followed by appropriate parametric...
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Low-Cost Flight Simulator with Possibility of Modeling of Flight Controls Failures
PublicationThe goal of this paper is to present a development of a low cost flight simulator, that allows to simulate flight controls failures. Cessna 172 has been chosen as an example of a general aviation aircraft and the flight model has been implemented in Simulink. The model allows for easy integration of an experimental autopilot, using various strategies. Aerodynamic coefficients have been calculated using software called DATCOM. Such...
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Structural Health Monitoring System for Suspension Footbridge
PublicationThe article presents the structural health monitoring (SHM) system installed in a footbridge in Radom. The main reason for the need for fitting of such a system was failed acceptance tests of the bridge. While under a dynamic load consisting of a group of 12 pedestrians jumping on the bridge, the bridge developed vibration during which acceleration of the deck of up to 4.5 m/s2 was recorded. Such behavior of the footbridge causes...
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The concept of research on ecological, energy and reliability effects of modified marine fuel oils application to supply compression-ignition engines in real conditions
PublicationWithin the article, basic assumptions of the research project financed by Regional Fund for Environmental Protection and Water in Gdansk were described. The project concerns the experimental investigations carried out on laboratory compression-ignition engine in conditions of its supply with a non-standard marine fuel oil. Configuration and measuring capability of laboratory test bed presently being constructed were introduced....
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Computational collective intelligence for enterprise information systems
PublicationCollective intelligence is most often understood as a kind of intelligence which arises on the basis of a group (collective) of autonomous unites (people, systems) which is taskoriented. There are two important aspects of an intelligent collective: The cooperation aspect and the competition aspect (Levy 1997). The first of them means the possibility for integrating the decisions made by the collective members for creating the decision of...
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Can Grand Design Doctrines Go Well with Locally Reinvented Urbanisms? Notes from Polish Cities in Transition
PublicationThe text explores how New Urbanism ideas, a comprehensive global design doctrine, transgress into the context of Polish planning practice. New Urbanism is considered through the perspective of the decentralization of a discussion on a planning policy and a modernization of a State, resulting form its post-Socialist urban change. In the text, New Urbanism is understood as a neotraditionalist movement i.e. drawing from the pre-modernist...
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Urban Railway within the Linear Urban Structure: the Case Study of Perm, Russia
PublicationThe paper analyses the ten years’ experience of Perm to develop its system of the urban train trying to reveal the reasons for its modest performance and decline in the passenger traffic. The authors show how the Urban Train fits within the city urban structure and eval uate the potential of the Urban Train to become a feasible solution to the problem of connecting the periphery with the city centre. Furthermore,...
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Effective Short -term Forecasting of Wind Farms Power
PublicationForecasting a specific wind farm's generation capacity within a 24 hour perpective requires both a reliable forecast of wind, as well as supporting tools. This tool is a dedicated model of wind farm power. This model should include not only general rules of wind to mechanical energy conversion, but also the farm's specific features. This paper present analytical, statistical, and neuron models of wind farm power. The study is based...
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DETERMINATION OF THE CITY CENTRE. STUDY FOR THE TROJMIASTO AGGLOMERATION
PublicationDetermination of the centre of the city or agglomeration or generally the geographic area is a task which is often undertaken as part of the promotional actions realized by local authorities or directly by inhabitants. Nowadays, especially due to the development and availability of positioning technology and satellite imaging, this job is undertaken within the framework of general didactic tasks and group projects during the study...
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Enhanced method of DS-CDMA low level singnals detection
PublicationThe following article comprises three main parts. The first one generally describes two methods of low level signals detection which are in the interest of this study. The signal spectrum averaging technique is shown as well as the method exploiting averaged spectrum of the signal raised to the power of 2n (nN). Additionally, this section briefly presents proposed enhancements and modifications of these two solutions, which allow...
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Power converter interface for urban DC traction substations - solutions and functionality.
PublicationThis paper focuses on extending an urban DC traction substation functionality by means of an additional power converter interface (PCI). In particular, by enabling bidirectional energy exchange between LV DC traction grid, AC grid and V2G chargers. Among other things, the presented material compares general attributes of the most promising DC/DC converters that can be used in a PCI, meet the requirements of galvanic isolation and...
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The demand for skills and labour cost in partner countries. Evidence from the enlarged EU
PublicationWe analyse the consequences of trade integration in Europe (1995-2005) detecting how the labour costs in partner countries affect the domestic demand for high- and low-skilled labour in 'Old' (EU-15) and five 'New' EU member states. In general, independently of the skill level of workers, the results suggest complementarity between domestic and foreign labour. However, when we take into account the typology of sectors, the demand...
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Strong Monogamies of No-Signaling Violations for Bipartite Correlation Bell Inequalities
PublicationThe phenomenon of monogamy of Bell inequality violations is interesting both from the fundamental perspective as well as in cryptographic applications such as the extraction of randomness and secret bits. In this article, we derive new and stronger monogamy relations for violations of Bell inequalities in general no-signaling theories. These relations are applicable to the class of binary output correlation inequalities known as...
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Straightened characteristics of McKendrick-von Foerster equation
PublicationWe study the McKendrick-von Foerster equation with renewal (that is the age-structured model, with total population dependent coefficient and nonlinearity). By using a change of variables, the model is then transformed to a standard age-structured model in which the total population dependent coefficient of the transport term reduces to a constant 1. We use this transformation to get existence, uniqueness of solutions of the problem...
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The importance and availability of marine certified reference materials
PublicationTraceability and reliable results are the two pillars of analytical methods; certified reference materials (CRMs) meet this requirement. ISO 17034:2016 credentials provide brief information on general requirements for the competence of Reference Material Producers (RMPs). The different types of CRMs have been produced in recent years for chemical analysis in food, water, soil, and sediment matrices in recent years. This review...
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NETWORKS, STAKEHOLDERS AND ENTREPRENEURIAL ECOSYSYSTEMS IN CURRENT POLISH ECONOMYGUT
PublicationThis book is dedicated to widely understood entrepreneurship and financial system in different polish ecosystems. In particular, there is described influence of supporting entrepreneurship to investment development in Walbrzych agglomerations communes with the results of questionnaires for varied groups of inhabitants, entrepreneurs and territorial self-governments. There is also presented analysis of relations within academic...
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Influence of drying mode and feed per tooth rate on the fine dust creation in pine and beech sawing on a mini sash gang saw
PublicationThe experimental results of the study focused on the effect of drying processes of modified air drying and warm air steam mixture drying of pine and beech wood on the size of sawdust particles created in cutting using PRW-15M sash gang saw, are presented in the paper. Particle size analysis of dry sawdust was performed using two methods—sieving method and laser diffraction analysis. The results showed that the drying process did...
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ROLA I ZNACZENIE SYSTEMÓW PRZELEWÓW NATYCHMIASTOWYCH A OBRÓT BEZGOTÓWKOWY W POLSCE
PublicationCelem pracy jest opis systemów szybkich przelewów w Polsce z uwagi na rosnące znaczenie obrotu bezgotówkowego. Artykuł wskazuje na genezę powstania systemów oraz ich rosnące znaczenie na rynku usług płatniczych. Celem szczegółowym jest zobrazowanie wzrostu liczby i wartości transakcji zrealizowanych przez systemy płatności natychmiastowych w Polsce oraz odniesienie wolumenu do statystyk systemu Elixir. Autor obrazuje korzyści płynące...
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De la façon dont les réseaux sociaux se croisent dans la vie des migrants
PublicationÉste es un texto muy complicado de titular. A pesar de lo sugerente de la idea de escribir acerca de dos conceptos intensamente relacionados, como son el de migración y el de redes. Esta misma intensidad en su interrelación implica una multiplicidad de sentidos que complican el trabajo explicativo del científico social, por su cuantioso número de opciones, y el trabajo comprensivo del lector, por la posible confusión que esta situación...
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Lessons learned in a decade: Medical‐toxicological view of tattooing
PublicationTattooing has been part of the human culture for thousands of years, yet only in the past decades has it entered the mainstream of the society. With the rise in popularity, tattoos also gained attention among researchers, with the aim to better understand the health risks posed by their application. 'A medical-toxicological view of tattooing'-a work published in The Lancet almost a decade ago, resulted from the international collaboration...
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Typing of Scopulariopsis and Microascus fungi by Random Amplified Polymorphic DNA (RAPD)
PublicationOBJECTIVES Scopulariopsis species and their teleomorphs of the genus Microascus are commonly isolated from soil, decaying plant material and indoor environments. Moreover, certain Scopulariopsis and Microascus species are recognised as opportunistic human pathogens. Although most species can be identified by detailed morphological study, phenotypic characters appear to overlap in several cases and morphology seems to be insufficient...
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The overview of reactors used for the production of precipitated calcium carbonate via carbonation route
PublicationCarbonation is one of the methods for the production of precipitated calcium carbonate (PCC) on the industrial scale. A gaseous CO2 is used as a reagent in this process. The hydrodynamic conditions gener-ated in the reactor affect the course of the process and the characteristics of the precipitated calcium carbonate particles. This paper discusses the construction of standard reactors and new proposed con-struction used for the...
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Polysaccharide-based Nanocomposites for Biomedical Applications: A Critical Review
PublicationPolysaccharides (PSA) are taking specific position among biomaterials for advanced applications in medicine. Nevertheless, poor mechanical properties is known as the main drawback of PSA, which highlights need for PSA modification. Nanocomposites PSA (NPSA) are a class of biomaterials widely used as biomedical platforms, but despite their importance and worldwide use have not been reviewed. Herein we critically reviewed application...
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Micellar Route of the Synthesis of Alkyl Xylosides: An Unexpected Effect of Amphiphilic Imidazolium Ionic Liquids
PublicationThis manuscript presents results from the investigation on the synthesis of alkyl xylosides by the novel, very efficient and promising protocol of the Fischer synthesis from unprotected xylose and aliphatic alcohol. The use of 1-alkyl-3-methylimidazolium hydrogen sulfate ionic liquids as the catalysts with dual functionality (surfactant + acid catalyst) and micellar reaction system are the main novelty of described method. It has...
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DETERMINANTS OF INLAND NAVIGATION ON THE VISTULA FROM WARSAW TO GDAŃSK
PublicationWaterborne transport is the cheapest, the safest and the least harmful to the natural environment. Restoring regular waterway cargo transport will require revitalisation of the existing trans-shipment and logistics infrastructure for commercial inland ports and building new. Transport policy makers must remember that waterborne transport is the most ecological type of transport. It produces only 10% of the gases emitted to the...
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Combinatorial scheme of finding minimal number of periodic points for smooth self-maps of simply connected manifolds
PublicationLet M be a closed smooth connected and simply connected manifold of dimension m at least 3, and let r be a fixed natural number. The topological invariant D^m_r [f], defined by the authors in [Forum Math. 21 (2009), 491-509], is equal to the minimal number of r-periodic points in the smooth homotopy class of f, a given self-map of M. In this paper, we present a general combinatorial scheme of computing D^m_r [f] for arbitrary dimension...
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Providing Differentiated Levels of Service Availability in VANET Communications
PublicationInter-vehicle communications seems to be a promising remedy not only for a number of road-safety issues, but also to improve the efficiency of road traffic, as well as to support the on-board infotainment applications. However, it often encounters disruptions due to high mobility of vehicles causing frequent failures of communication links. In this paper, we utilize the idea of multipath vehicle-to-vehicle routing to provide protection...
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Application of BAN Network to Increase Security in Transport Systems
PublicationIn the article general characteristics of the BAN network with M2M communications are presented. These are networks that enable the implementation of wireless transmission of signals using special sensors located on the body or implanted subcutaneously. These sensors allow monitoring of different type life parameters of a human. In the next part of work there is proposed the implementation of BAN networks to transport systems as...
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Excited state properties of a series of molecular photocatalysts investigated by time dependent density functional theory.
PublicationTime dependent density functional theory calculations are applied on a series of molecular photocatalysts of the type [(tbbpy)2M1(tpphz)M2X2]2+ (M1 = Ru, Os; M2 = Pd, Pt; X = Cl, I) in order to provide information concerning the photochemistry occurring upon excitation of the compounds in the visible region. To this aim, the energies, oscillator strengths and orbital characters of the singlet and triplet excited states are investigated....
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EXHAUST GAS TEMPERATURE MEASUREMENTS IN DIAGNOSTICS OF TURBOCHARGED MARINE INTERNAL COMBUSTION ENGINES PART II DYNAMIC MEASUREMENTS
PublicationThe second part of the article describes the technology of marine engine diagnostics making use of dynamic measurements of the exhaust gas temperature. Little-known achievements of Prof. S. Rutkowski of the Naval College in Gdynia (now: Polish Naval Academy) in this area are presented. A novel approach is proposed which consists in the use of the measured exhaust gas temperature dynamics for qualitative and quantitative assessment...
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On the interspike-intervals of periodically-driven integrate-and-fire models
PublicationWe analyze properties of the firing map, which iterations give information about consecutive spikes, for periodically driven linear integrate-and-fire models. By considering locally integrable (thus in general not continuous) input functions, we generalize some results of other authors. In particular, we prove theorems concerning continuous dependence of the firing map on the input in suitable function spaces. Using mathematical...
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THE INFLUENCE OF GESTALT THEORY ON ERNST CASSIRER’S PHENOMENOLOGY OF SYMBOLIC FORMS
PublicationIn the opinion of many scholars the notion of symbolic pregnancy is one of the key concepts in Ernst Cassirer’s philosophy of symbolic forms. Without a proper under-standing of its conceptual frame Cassirer’s philosophy lacks a consistent foundation. The notion symbolic pregnancy offers the mechanism of distinction of symbolic forms. The newest investigations (also in unpublished or less known, neglected writings of the philosopher)...
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Influence of pitting corrosion on fatigue and corrosion fatigue of ship and offshore structures. Part II: Load - pit crack interaction
PublicationIn the paper has been discussed influence of stresses on general corrosion rate and corrosion pit nucleation and growth rate, whose presence has been questioned by some authors but accepted by most of them. Influence of pit walls roughness on fatigue life of a plate suffering pit corrosion and presence of so called "non damaging" pits which never lead to initiation of fatigue crack, has been presented. Possibility of prediction...
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Optimization of Hydrogen - Evolving Photochemical Molecular Devices
PublicationA molecular photocatalyst consisting of a RuII photocenter, a tetrapyridophenazine bridging ligand, and a PtX2 (X=Cl or I) moiety as the catalytic center functions as a stable system for light-driven hydrogen production. The catalytic activity of this photochemical molecular device (PMD) is significantly enhanced by exchanging the terminal chlorides at the Pt center for iodide ligands. Ultrafast transient absorption spectroscopy...
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Towards the boundary between easy and hard control problems in multicast Clos networks
PublicationIn this article we study 3-stage Clos networks with multicast calls in general and 2-cast calls, in particular. We investigate various sizes of input and output switches and discuss some routing problems involved in blocking states. To express our results in a formal way we introduce a model of hypergraph edge-coloring. A new class of bipartite hypergraphs corresponding to Clos networks is studied. We identify some polynomially...
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Vibration monitoring of structures in the light of the Polish and international requirements
PublicationThe paper concerns the wide range of strategies used to protect structures against man-made dynamic excitation. The most popular approaches applied worldwide are compared, and the main differences and similarities are summarized. The literature studies are supported by the results of the measurements performed on different types of real structures, which are sensitive and insensitive to the dynamic load. To make the conclusions...
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Superstitions and customs in construction - a contribution to the discussion on the disappearance of this tradition
PublicationConstruction is one of the most important, but also the most extensive areas of the economy. That is why we encounter superstitions and customs related to this discipline of the economy quite often:we blew and repeat them, not even knowing what their origin is and what according to old beliefs resulted in their lack of application. This situation applies in practice to all buildings, including residential buildings implemented...
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Kernel PCA in Application to Leakage Detection in Drinking Water Distribution System
PublicationMonitoring plays an important role in advanced control of complex dynamic systems. Precise information about system's behaviour, including faults detection, enables efficient control. Proposed method- Kernel Principal Component Analysis (KPCA), a representative of machine learning, skilfully takes full advantage of the well known PCA method and extends its application to nonlinear case. The paper explains the general idea of KPCA...
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Simple and low-cost wireless voting system
PublicationThis paper presents the concept of a simple and low-cost wireless voting system working on the 868 MHz frequency band. Described system is dedicated to general shareholders assemblies but it can be easily adapted for other applications. The main advantage is its simplicity and mobility as it consists solely of three components - voting modules, base station and a PC application from which the whole system is managed. This architecture...
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A new cold-active β-galactosidase from Arthrobacter sp. S3* - gene cloning, overexpression, purification and properties
PublicationA psychrotrophic bacterium producing a cold-active β-galactosidase was isolated from Spitsbergen soil and classified as Arthrobacter sp. S3*. The gene encoding β-galactosidase was isolated from the genomic DNA library, sequenced, cloned, expressed in Escherichia coli, purified by ion exchange chromatography and characterized. The Arthrobaster sp. S3* β-galactosidase is a homotrimeric enzyme composed of 74,4 kDa subunits. It is...
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Self-adwokatura jako forma wolontariatu osób z niepełnosprawnością
PublicationSelf-advocacy is both a competence necessary for independent adult life and a form of activity of people with disability in terms of exercising their rights to self-determine. It is also a form of social inclusion and participation, often having a character of volunteer engagement of people with disability in work for their minority group. Although the access of people with disability to the sphere of supporting other people...
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Defense mechanisms and borderline personality organization among COVID-19 believers and non-believers during complete lock-down
PublicationThe aim of the current study was to investigate whether a specific social perception of the pandemic—believing or not in COVID-19—predicts borderline personality organizations and whether this relationship is mediated by more primitive maladaptive mechanisms—splitting, denial, and dissociation. The online study included 720 organization aged 25–45. Participants were diverse in terms of place of residence, being in a relationship,...