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Receptor for advanced glycation end‐products: Biological significance and imaging applications
PublikacjaThe receptor for advanced glycation end-products (RAGE or AGER) is a transmembrane, immunoglobulin-like receptor that, due to its multiple isoform structures, binds to a diverse range of endo- and exogenous ligands. RAGE activation caused by the ligand binding initiates a cascade of complex pathways associated with producing free radicals, such as reactive nitric oxide and oxygen species, cell proliferation, and immunoinflammatory...
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Behavior of residual current devices at frequencies up to 50 kHz
PublikacjaThe use of residual current devices (RCDs) is obligatory in many types of low-voltage circuits. They are devices that ensure protection against electric shock in the case of indirect contact and may ensure additional protection in the case of direct contact. For the latter purpose of protection, only RCDs of a rated residual operating current not exceeding 30 mA are suitable. Unfortunately, modem current-using equipment supplied...
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‘Acridines’ as New Horizons in Antifungal Treatment
PublikacjaFrequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide. The repertoire of antifungal chemotherapeutic agents is very limited. Although new antifungal drugs such as lanosterol 14α-demethylase and β-glucan synthase inhibitors have been introduced into clinical...
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Comparison of High Performance Liquid Chromatography Methods with Different Detectors for Determination of Steroid Hormones in Aqueous Matrices
PublikacjaThis paper presents the development and comparison of procedures for the qualitative and quantitative determination of five estrogenic compounds (17-a-ethynylestradiol, estrone, estradiol, estriol, and progesterone) in drinking water and wastewater samples. Five extraction columns and two disks were tested for their efficiency. The C18 columns were superior on the basis of cost for solid phase extraction of drinking water or sewage....
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First report of seroprevalence of Toxoplasma gondii infection in sheep in Pomerania, northern Poland
PublikacjaIntroduction and objective. Toxoplasmosis is parasitic disease which has economic relevance for both veterinary and human medicine. In sheep, toxoplasmosis is a major cause of abortion and can thus cause reproductive problems. The current study aimed to determine the occurrence of anti-Toxoplasma gondii IgG antibodies in sheep from 13 districts of northern Poland and thereby obtain actual data about T. gondii seroprevalence in...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublikacjaBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Fracture Areas Quantitative Investigating of Bending-Torsion Fatigued Low-Alloy High-Strength Steel
PublikacjaIn this study, the impact of pseudo-random non-proportional bending-torsion fatigue loadings proportion on the fatigue life and the fracture surface topography was analyzed. Investigation was carried out for 24 specimens made of S355J2 steel with 11 different ratios of maximum stresses λ. For these cases, after the fatigue tests, the surface topography measurements were carried out using an optical profilometer, using the focus...
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Thermomagnetic behavior of a semiconductor material heated by pulsed excitation based on the fourth-order MGT photothermal model
PublikacjaThis article proposes a photothermal model to reveal the thermo-magneto-mechanical properties of semiconductor materials, including coupled diffusion equations for thermal conductivity, elasticity, and excess carrier density. The proposed model is developed to account for the optical heating that occurs through the semiconductor medium. The Moore–Gibson–Thompson (MGT) equation of the fourth-order serves as the theoretical framework...
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On reliability assessment of ship machinery system in different autonomy degree; A Bayesian-based approach
PublikacjaAnalyzing the reliability of autonomous ships has recently attracted attention mainly due to epistemic uncertainty (lack of knowledge) integrated with automatic operations in the maritime sector. The advent of new random failures with unrecognized failure patterns in autonomous ship operations requires a comprehensive reliability assessment specifically aiming at estimating the time in which the ship can be trusted to be left unattended....
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Predictions of cervical cancer identification by photonic method combined with machine learning
PublikacjaCervical cancer is one of the most commonly appearing cancers, which early diagnosis is of greatest importance. Unfortunately, many diagnoses are based on subjective opinions of doctors—to date, there is no general measurement method with a calibrated standard. The problem can be solved with the measurement system being a fusion of an optoelectronic sensor and machine learning algorithm to provide reliable assistance for doctors...
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Copolymerization of Styrene and Pentadecylphenylmethacrylate (PDPMA): Synthesis, Characterization, Thermomechanical and Adhesion Properties
PublikacjaThe copolymerization of styrene (St) with a bioderived monomer, pentadecylphenylmethacrylate (PDPMA), via atom transfer radical polymerization (ATRP) was studied in this work.The copolymerization reactivity ratio was calculated using the composition data obtained from1HNMR spectroscopy, applying Kelen-Tudos and Finemann-Ross methods. The reactivity ratio of styrene (r1=0.93) and PDPMA (r2=0.05) suggested random copolymerization...
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Noise sources in Raman spectroscopy of biological objects
PublikacjaWe present an overview of noise sources deteriorating the quality of the recorded biological Raman spectra and the ability to determine the specimen composition. The acquired Raman spectra exhibit intense additive noise components or drifts because of low intensity of the scattered light. Therefore we have to apply expensive or bulky measurement setups to limit their inherent noise or to apply additional signal processing to reduce...
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Shear fracture of longitudinally reinforced concrete beams under bending using Digital Image Correlation and FE simulations with concrete micro-structure based on X-ray micro-computed tomography images
PublikacjaThe paper presents experimental and numerical investigations of the shear fracture in rectangular concrete beams longitudinally reinforced with steel or basalt bar under quasi-static three point bending. Shear fracture process zone formation and development on the surface of beams was investigated by Digital Image Correlation (DIC) whereas thorough analyses of 3D material micro-structure, air voids, width and curvature of shear...
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Integrated model for the fast assessment of flood volume: Modelling – management, uncertainty and sensitivity analysis
PublikacjaThe specific flood volume is an important criterion for assessing the performance of sewage networks. It has been shown that its value is greatly influenced by the layout of the sewers in the catchment area, which is usually expressed by a fractal dimension. Currently, only mechanistic models (such as SWMM) enable the determination of the impact of the layout of the sewers on flooding volume, but they require additional and robust...
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Evolving neural network as a decision support system — Controller for a game of “2048” case study
PublikacjaThe paper proposes an approach to designing the neuro-genetic self-learning decision support system. The system is based on neural networks being adaptively learned by evolutionary mechanism, forming an evolved neural network. Presented learning algorithm enables for a selection of the neural network structure by establishing or removing of connections between the neurons, and then for a finding the beast suited values of the network...
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Electrical properties of Na2O-CaO-P2O5 glasses doped with SiO2 and Si3N4
PublikacjaSodium-calcium-phosphate glasses doped with SiO2 or Si3N4 having similar sodium ion concentrations were prepared by melt quenching. The conductivity was measured by impedance spectroscopy under nitrogen atmosphere in a wide frequency range (10 mHz–1 MHz) and wide temperature range (153–473 K). At 36.6 °C, DC conductivities of all glasses vary between 1.1 ∗ 10−12 and 8.9 ∗ 10−12 S cm−1 and have similar activation energies (between...
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Soft Sensor Application in Identification of the Activated Sludge Bulking Considering the Technological and Economical Aspects of Smart Systems Functioning
PublikacjaThe paper presented the methodology for the construction of a soft sensor used for activated sludge bulking identification. Devising such solutions fits within the current trends and development of a smart system and infrastructure within smart cities. In order to optimize the selection of the data-mining method depending on the data collected within a wastewater treatment plant (WWTP), a number of methods were considered, including:...
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Thermal, electrical, and magnetic properties of Fe2O3–PbO–SiO2 glass prepared by traditional melt-quenching and twin roller fast-cooling methods
PublikacjaIn this study, Fe–Pb–Si oxide glasses containing between 12.5 and 17.5 mol% Fe2O3 were prepared using two different methods comprising traditional melt-quenching and twin roller fast-cooling techniques. The topography and structure of the materials obtained were characterized by X-ray powder diffraction and scanning electron microscopy. All of the materials were found to be amorphous. The topography of most of the glasses comprised...
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Automatic labeling of traffic sound recordings using autoencoder-derived features
PublikacjaAn approach to detection of events occurring in road traffic using autoencoders is presented. Extensions of existing algorithms of acoustic road events detection employing Mel Frequency Cepstral Coefficients combined with classifiers based on k nearest neighbors, Support Vector Machines, and random forests are used. In our research, the acoustic signal gathered from the microphone placed near the road is split into frames and converted...
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Discrete element method simulations of fracture in concrete under uniaxial compression based on its real internal structure
PublikacjaThe paper describes experimental and numerical results of concrete fracture under quasi-static uniaxial compression. Experimental uniaxial compression tests were performed on concrete cubic specimens. Fracture in concrete was detected at the aggregate level by means of three non-destructive methods: three-dimensional X-ray microcomputed tomography, two-dimensional scanning electron microscope and manual two-dimensional digital...
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Redevelopment of Russian closed towns: The Example of Zato "Zvezdniy"
PublikacjaThe current economic crisis is having a strong impact on socio-economic processes in the development of Russian cities. The impact of the crisis is particularly strong on city territory where the activity of core industrial enterprises, military units or similar institutions has been stopped. In such cases, the situation is directly related to the functioning of military units or one industrial enterprise responsible for the formation...
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Reaction of aniline with ammonium persulphate and concentrated hydrochloric acid: Experimental and DFT studies
PublikacjaIn this paper, the reaction of aniline with ammonium persulphate and concentrated HCl was studied. As a result of our experimental studies, 2,4,6-trichlorophenylamine was identified as the main product. This shows that a high concentration of HCl does not favour oxidative polymerisation of phenylamine, even though the ammonium persulphate/HCl system is widely used in polyaniline synthesis. On the basis of the experimental data...
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Multimodal Genetic Algorithm with Phase Analysis to Solve Complex Equations of Electromagnetic Analysis
PublikacjaIn this contribution, a new genetic-algorithm-based method of finding roots and poles of a complex function of a complex variable is presented. The algorithm employs the phase analysis of the function to explore the complex plane with the use of the genetic algorithm. Hence, the candidate regions of root and pole occurrences are selected and verified with the use of discrete Cauchy's argument principle. The algorithm is evaluated...
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Inhibition of the granular anammox process by the high concentration of free ammonia.
PublikacjaHigh concentrations of ammonia and nitrite, typical for reject water treatment in the anammox process with the use of high temperatures and pH, may cause free ammonia (FA) inhibition. In this study, the inhibitory effect of FA on anammox process rate was investigated in a bench-scale sequencing batch reactor (SBR) with granular anammox biomass. Results of the study present that the anammox process could be successfully operated...
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Birds' feathers – Suitable samples for determination of environmental pollutants
PublikacjaThe intensive development of industry and human population results in large amounts of different xenobiotic emitted into individual ecosystem components. As a consequence, monitoring of the level of pollution of particular elements of the environment by exotoxins has become a common interest. The determination of environmental changes by different types of biological indicators is called bioindication, which is used as one of the...
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Klasyfikator SVM w zastosowaniu do synchronizacji sygnału OFDM zniekształconego przez kanał wielodrogowy
PublikacjaW pracy przedstawiono analizę przydatności klasyfikatora SVM bazującego na uczeniu maszynowym do estymacji przesunięcia czasowego odebranego symbolu OFDM. Przedstawione wyniki wykazują, że ten klasyfikator potrafi zapewnić synchronizację dla różnych kanałów wielodrogowych o wysokim poziomie szumu. Eksperymenty przeprowadzone w Matlabie z użyciem modeli modulatora i demodulatora wykazały, że w większości przypadków klasyfikator...
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Radio programowalne - przyszły standard inteligentnego systemu radiokomunikacyjnego
PublikacjaW pracy przedstawiono całkowicie nowatorską koncepcję programowalnego systemu radiokomunikacyjnego zwłaszcza w odniesieniu do inteligentnego terminala użytkownika w tym systemie. Na wstępie omówiono platformę sprzętową takiego rozwiązania. Następnie przedstawiono rozwiązanie systemowe platformy informatycznej, poczynając od jej charakterystyki funkcjonalnej, poprzez opis środowiska programowego koniecznego do realizacji niezbędnych...
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Effect of Ethanol Extracts of Propolis (EEPs) against Staphylococcal Biofilm—Microscopic Studies
PublikacjaStaphylococci growing in the form of biofilm exhibit high resistance to a plethora of antibiotics. The aim of the study was to assess the influence of ethanolic extract of propolis (EEPs) on S. epidermidis ATCC 35984 biofilm using fluorescent microscopy. Propidium iodide (PI) and SYTO 9 were used for differentiation of live and dead cells, and calcofluor white was used to stain the extracellular matrix, the self-produced extracellular...
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A New Metric for Long-Range Transport Potential of Chemicals
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The Many Faces of Enterococcus spp.—Commensal, Probiotic and Opportunistic Pathogen
PublikacjaEnterococcus spp. are Gram-positive, facultative, anaerobic cocci, which are found in the intestinal flora and, less frequently, in the vagina or mouth. Enterococcus faecalis and Enterococcus faecium are the most common species found in humans. As commensals, enterococci colonize the digestive system and participate in the modulation of the immune system in humans and animals. For many years reference enterococcal strains have...
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Analysis of Video Transmission Capabilities in a Simulated OFDM-Based Supplementary BPL-PLC System
PublikacjaThe design and maintenance of a reliable communication system, especially in harsh working conditions for the oil and mining industry, brings many challenges. With the use of a video transmission system, one can monitor the crew and their working environment. Broadband over power line–power line communication (BPL-PLC) seems an ideal medium for such a service, since it enables the use of the existing wired infrastructure for supplementary...
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Bearing estimation using double frequency reassignment for a linear passive array
PublikacjaThe paper demonstrates the use of frequency reassignment for bearing estimation. For this task, signals derived from a linear equispaced passive array are used. The presented method makes use of Fourier transformation based spatial spectrum estimation. It is further developed through the application of two-dimensional reassignment, which leads to obtaining highly concentrated energy distributions in the joint frequency-angle domain...
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DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
PublikacjaThe human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylated region (DMR) encompassing HLA-DRB1 exon 2 is particularly affected and displays methylation-sensitive regulatory properties in vitro. Causal inference and Mendelian randomization...
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Hybridized PWM Strategy for Three- and Multiphase Three-Level NPC Inverters
PublikacjaA simple hybridized pulsewidth modulation (PWM) algorithm for three- and multiphase three-level neutral point clamped (NPC) inverters is proposed. The proposed solution is based on classical space vector PWM (SVPWM) algorithms for two-level inverters but can also be based on sinusoidal PWM with min–max injection. An additional level of output voltage is obtained by modifying the resulting switching patterns taking into account...
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Gdańsk Urban Initiative Laboratory
PublikacjaGdansk is Poland's principal seaport, situated on the southern edge of the Gdansk Bay on the Baltic Sea. The city is the capital and largest city of the Pomeranian Voivodeship. Gdansk, in a conurbation with the city of Gdynia and the resort town of Sopot, and suburban communities, jointly forms Poland's fourth largest metropolitan area, with a population approaching 1.4 million. The pathways towards the Micro ULL FWE Nexus Square...
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Pharmacomicrobiomics of cell-cycle specific anti-cancer drugs – is it a new perspective for personalized treatment of cancer patients?
PublikacjaIntestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotrans-formation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobiotics. However, there is another side to the coin. Pharmacotherapeutic agents can significantly modify the microbiota, which consequently affects their efficacy. In this review, we comprehensively...
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Safety Assessment of the Regional Warmia and Mazury Road Network Using Time-Series Analysis
PublikacjaWarmia and Mazury still belongs to the areas with the smallest transport accessibility in Europe. Unsatisfactory state of road infrastructure is a major barrier to the development of the regional economy, impacting negatively on the life conditions of the population. Also in terms of road safety Warmia and Mazury is one of the most endangered regions in Poland. The Police statistics show that beside a high pedestrian risk observed...
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In vitro biodegradation of bacterial nanocellulose under conditions simulating human plasma in the presence of selected pathogenic microorganisms
PublikacjaThe Biodegradability of bacterial nanocellulose (BNC) was assessed based on a change in its properties under conditions simulating human plasma in the presence or absence of the pathogens Staphylococcus aureus, Candida albicans and Aspergillus fumigatus. It was shown that the dry mass of BNC did not change during 6 months of incubation, except for samples stored in the presence of moulds, where the dry mass reduced by 40 %. The...
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Ageing of Society — Local Disparities. Classification of the Pomorskie Voivodship Communes According to the Pace and Progress of Local Communities’ Ageing
PublikacjaThe article deals with the issues of local disparities in the field of advancement and pace of demographic ageing. The subjects of the research were communes of the Pomorskie Voivodship. The purpose of the article — i.e., diagnosing and assessing the progress and pace of ageing of local communities in all 123 communes of the Pomorskie Voivodship, was achieved using a combination of traditional measures of ageing: age factor,...
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Application of Extreme Doses of Aluminium for Growth Control of Filmentous Bacteria Microthrix Parvicella in an Activated Sludge System - Laboratory Investigations
PublikacjaLaboratory investigations of aluminium (PAX-16) application for control of population of filamentous bacteria Microthrix Parvicella in a three-phase bioreactor in lab-scale were performed. Dosing of small aluminium doses (approximately 0.5 mgAl/gMLSS·d) in the period preceding seasonal growth of M.Parvicella failed to prevent mass growth of this microorganism leading to activated sludge bulking phenomenon (SVI-250 ml/gMLSS)...
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Defense mechanisms and borderline personality organization among COVID-19 believers and non-believers during complete lock-down
PublikacjaThe aim of the current study was to investigate whether a specific social perception of the pandemic—believing or not in COVID-19—predicts borderline personality organizations and whether this relationship is mediated by more primitive maladaptive mechanisms—splitting, denial, and dissociation. The online study included 720 organization aged 25–45. Participants were diverse in terms of place of residence, being in a relationship,...
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Environmental aspects of shale gas recovery in Baltic Basin
PublikacjaFactors limiting shale gas exploration and exploitation in Pomorskie Voivodeship are presented. In particular, ground and surface water availability and land/community impact is discussed. Production from unconventional reservoirs requires proper well completion through hydraulic fracturing, hence voluminous streams of water are needed – in total 8000 to 20000 m3 per 1000 m of borehole length. 17 major groundwater basins were characterized....
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Excited state properties of a series of molecular photocatalysts investigated by time dependent density functional theory.
PublikacjaTime dependent density functional theory calculations are applied on a series of molecular photocatalysts of the type [(tbbpy)2M1(tpphz)M2X2]2+ (M1 = Ru, Os; M2 = Pd, Pt; X = Cl, I) in order to provide information concerning the photochemistry occurring upon excitation of the compounds in the visible region. To this aim, the energies, oscillator strengths and orbital characters of the singlet and triplet excited states are investigated....
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Reinforcement Learning Algorithm and FDTD-based Simulation Applied to Schroeder Diffuser Design Optimization
PublikacjaThe aim of this paper is to propose a novel approach to the algorithmic design of Schroeder acoustic diffusers employing a deep learning optimization algorithm and a fitness function based on a computer simulation of the propagation of acoustic waves. The deep learning method employed for the research is a deep policy gradient algorithm. It is used as a tool for carrying out a sequential optimization process the goal of which is...
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Diagnostic Model of Crankshaft Seals
PublikacjaT he paper presents a research stand being a diagnostic model of radial lip seals used, among others, on crankshafts of piston combustion engines in order to identify the correctness of their operation. The possibility of determining the technical condition of lip seals on the basis of the proposed coefficient of correctness of operation has been described. T he basic features of seals influencing their correctness of...
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Incorporating installation effects into the probability analysis of controlled modulus columns
PublikacjaThis technical report presents the probabilistic analysis which integrates the Monte Carlo simulation (MCS) with random field theory to model the load–displacement behavior of Controlled Modulus Columns (CMCs) in overconsolidated Poznań clay. Presented study focuses on the practical aspects of statistical analysis of geotechnical data, numerical model development, and results evaluation. Variability and spatial distribution of...
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Controlling crystallites orientation and facet exposure for enhanced electrochemical properties of polycrystalline MoO3 films
PublikacjaThis study focuses on the development and optimization of MoO3 films on commercially available FTO substrates using the pulsed laser deposition (PLD) technique. By carefully selecting deposition conditions and implementing post-treatment procedures, precise control over crystallite orientation relative to the substrate is achieved. Deposition at 450 °C in O2 atmosphere results in random crystallite arrangement, while introducing...
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Problems of varistor quality assessment during exploitation
PublikacjaVaristors are commonly used elements which protect power supply networks against high-voltage surges or lightning. Therefore, quality and endurance of these elements is important to avoid losses when an expensive laboratory equipment would not be protected from random overvoltages. Additionally, excessive leakage currents generate serious costs due to high energy consumption. The paper presents shortly properties of varistors that...
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Water-mediated influence of a crowded environment on internal vibrations of a protein molecule
PublikacjaThe influence of crowding on the protein inner dynamics is examined by putting a single protein molecule close to one or two neighboring protein molecules. The presence of additional molecules influences the amplitudes of protein fluctuations. Also, a weak dynamical coupling of collective velocities of surface atoms of proteins separated by a layer of water is detected. The possible mechanisms of these phenomena are described....
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Computing algebraic transfer entropy and coupling directions via transcripts
PublikacjaMost random processes studied in nonlinear time series analysis take values on sets endowed with a group structure, e.g., the real and rational numbers, and the integers. This fact allows to associate with each pair of group elements a third element, called their transcript, which is defined as the product of the second element in the pair times the first one. The transfer entropy of two such processes is called algebraic transfer...