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Wyniki wyszukiwania dla: SOLE DIAZONIOWE
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In vitro enzyme kinetics and NMR-based product elucidation for glutathione S-conjugation of the anticancer unsymmetrical bisacridine C-2028 in liver microsomes and cytosol: major role of glutathione S-transferase M1-1 isoenzyme
PublikacjaThis work is the next step in studying the interplay between C-2028 (anticancer-active unsymmetrical bisacridine developed in our group) and the glutathione S-transferase/glutathione (GST/GSH) system. Here, we analyzed the concentration- and pH-dependent GSH conjugation of C-2028 in rat liver microsomes and cytosol. We also applied three recombinant human GST isoenzymes, which altered expression was found in various tumors. The...
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Intranet and internal communication in an organization
PublikacjaOne of the conditions of an organizational effectiveness is acommunication. However, communication meets some obstacles. Newtechnological opportunities, such as Intranet support enterprise communication process and bring some benefits. This paper includes: the description of communication process and its barriers, the analyze of relationships between communication and an organizational effectiveness, advantages from implementing...
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The role and importance of the intellectual capital of the academic library – Gdańsk Tech Library Circulation Services case study / Rola kapitału intelektualnego biblioteki akademickiej na przykładzie doświadczeń Sekcji Obsługi Czytelnika Biblioteki Politechniki Gdańskiej
PublikacjaSkuteczne zarządzanie zasobami kapitału intelektualnego danej sekcji biblioteki akademickiej może być jednym z czynników wpływających na wysokie oceny usług bibliotecznych jej użytkowników. Może ono wpływać na wzrost kapitału intelektualnego biblioteki akademickiej, w strukturach której się znajduje. W sposób pośredni może oddziaływać również na poziom kapitału intelektualnego uczelni. Głównym celem autorek było przedstawienie...
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Obyś cudze dzieci uczył! Magia zawodu czy przekleństwo wszech czasów? Na wstępie od redaktorki – bardzo osobiście [Teaching as such. A glamorous profession or a curse of all time? Some introductory remarks from the editor]
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Multidisciplinary Open System Transferring Knowledge for R2B Development
PublikacjaDespite many efforts, there is still a serious problem in transferring knowledge from research to business. The problem is especially visible in Poland – the cooperation of R2B is ineffective. We are trying to solve this problem using some IT support. The manuscript presents some solutions developed at the Gdańsk University of Technology. In particular, the platform called “MOST Knowledge” is deeply described. Its layer architecture,...
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Swarm Algorithms in Modern Engineering Optimization Problems
PublikacjaComplexity of today engineering problems is constantly increasing. Scientists no longer are facing issues, for which simple, mathematical programming methods are sufficient. Issues like autonomic vehicle navigation or classification are considered to be challenging, and although there exist valid means to solve them, in some cases there still is some place for improvement. With emergence of a new type of optimization techniques...
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Die rolle von Chats/Diskussionsforen im eLearning an einem praktischen Bespiel, Die rolle von Chats/Diskussionsforen im eLearning an einem praktischen Bespiel. A practical example of the role of chatrooms/discussion forums in e-learning.
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Mathematical Modelling and Effect Size Analysis in Support of Searching for the Proteomic Signature of Radiotherapy Toxicity
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Low-Molecular-Weight Aldehyde Inhibitors of Cathepsin G
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Development and test of fex, a fingers extending exoskeleton for rehabilitation and regaining mobility
PublikacjaThis paper presents the design process of an exoskeleton for executing human fingers' extension movement for the rehabilitation procedures and as an active orthosis purposes, together with its first clinical usability tests of a robotic exoskeleton. Furthermore, the Fingers Extending eXoskeleton (FEX) is a serial, under-actuated mechanism capable of executing fingers' extension. FEX is based on the state-of-art FingerSpine serial...
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FEX a Fingers Extending eXoskeleton for Rehabilitation and Regaining Mobility
PublikacjaThis paper presents the design process of an exoskeleton for executing human fingers’ extension movement for the rehabilitation procedures and as an active orthosis purposes. The Fingers Extending eXoskeleton (FEX) is a serial, under-actuated mechanism capable of executing fingers’ extension. The proposed solution is easily adaptable to any finger length or position of the joints. FEX is based on the state-of-art FingerSpine serial...
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Enhanced photocatalytic activity of transparent carbon nanowall/TiO2 heterostructures
PublikacjaThe synthesis of novel tunable carbon-based nanostructure represented a pivotal point to enhance the efficiency of existing photocatalysts and to extend their applicability to a wider number of sustainable processes. In this letter, we describe a transparent photocatalytic heterostructure by growing boron-doped carbon nanowalls (B-CNWs) on quartz, followed by a simple TiO2 sol-gel deposition. The effect on the thickness and boron-doping...
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Enhancing Product Manufacturing through Smart Virtual Product Development (SVPD) for Industry 4.0
PublikacjaABSTRACT This paper proposes the Smart Virtual Product Development (SVPD) system, which enhances the industrial product manufacturing processes. The proposed system comprises of three main modules: design knowledge management (DKM), manufacturing capability analysis and process planning (MCAPP), and product inspection planning (PIP). Smart virtual product development system collects, stores, and uses experiential knowledge from...
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Statistics with R A Handbook for Statistical Analysis with R and R-Studio
PublikacjaIf you are to perform any kind of data (statistical) analysis and use tools in the data science ecosystem, you may have seen a variety of tutorials, handbooks online (I’m not mentioning traditional bibles of statistics). Unfortunately most of them is written intentionally for specific purposes and/or target group of people and does not include many aspects, data types, difficult aspects, usually hiding them trying to solve theoretical...
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Failure of cold-formed beam: How does residual stress affect stability?
PublikacjaIn machine industry, stresses are often calculated using simple linear FEM analysis. Occasional failures of elements designed in such a way require recomputation by means of more sophisticated methods, eg. including plasticity and non-linear effects. It usually leads to investigation of failure causes and improvement of an element in order to prevent its unwanted behavior in the future. The study presents the case where both linear...
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Uczenie maszynowe do samoorganizacji systemów rozproszonych w zastosowaniach gospodarczych
PublikacjaW pracy omówiono uczenie maszynowe do samoorganizacji systemów rozproszonych w zastosowaniach gospodarczych ze szczególnym uwzględnieniem sieci neuronowych do predykcji finansowych oraz szacowania ratingu przedsiębiorstw. Oprócz sieci neuronowych, istotną rolę w przygotowaniu i testowaniu informatycznych systemów finansowych może pełnić programowanie genetyczne. Z tego powodu omówiono uczenie maszynowe w aplikacjach konstruowanych...
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Corporate Governance and Ownership Structure in the Top 30 Listed Non Financial Companies in Poland
PublikacjaThis paper offers a first analysis of the relationships between corporate governance models and rules and ownership structure of the top 30 Polish firms listed at the WSE (not considering foreign firms and/or the Polish branches of foreign firms listed at the same stock exchange, nor the financial companies and the banks). The general picture depicted by this analysis is putting into evidence the increasing importance of institutional...
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Environmental Impacts of Renewable Energy Technologies
PublikacjaNowadays, fossil fuels are the main sources energy from which electricity is obtained. But these sources will not last forever, so in due course renewable energies will have to replace them in this role. All energy sources have some impact on our environment. Fossil fuels — coal, oil, and natural gas — do substantially more harm than renewable energy sources by most measures, including air and water pollution, damage to public...
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Ocena odporności powłok na bazie DLC na doraźne uszkodzenie w warunkach tarcia ślizgowego ze smarowaniem wodą i solą fizjologiczną = Evaluation of DLC based coatings resistance to instanteneous damage under sliding friction conditions with distilated water or saline lubrication
PublikacjaWykonano serię testów w celu wyznaczenia granicznych warunków wymuszenia, zdefiniowaego jako średnie naciski powierzchniowe oraz prędkość ślizgania, po przekroczeniu których następuje gwałtowne zniszczenie powłoki. Na podstawie wyników pomiarów opracowano aproksymowane charakterystyki granicznych wymuszeń w układzie p - v oraz pokrewnych dla badanych materiałów, smarów i zakresu parametrów wymuszenia.
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Inhibitors of angiogenesis in cancer therapy – synthesis and biological activity
PublikacjaAngiogenesis is the process of formation of new capillaries from preexisting blood vessels. Angiogenesis is involved in normal physiological processes, and plays an important role in tumor invasion and development of metastases. Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. VEGF is a mitogen for vascular endothelial cells and stimulates their proliferation. By inhibiting the biological activity of...
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Synthesis of Novel Polycationic Quaternary Di- and Trispirocyclic Benzenes
PublikacjaTreatment of hexakis(bromomethyl)benzene with a cyclic amine {morpholine, 1-methylpiperazine, 1-(2-hydroxyethyl)piperazine, isonipecotamide, 4-hydroxypiperidine, 4-[3-(4-piperidyl)propyl]-1-piperidineethanol} gave a range of di- and trispirocyclic ammonium salts in satisfactory yields (22-62%). Presumably, the electrostatic and repulsion forces play an important role in their formation. The structure in soln. and the protonation...
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Big Data Paradigm Developed in Volunteer Grid System with Genetic Programming Scheduler
PublikacjaArtificial intelligence techniques are capable to handle a large amount of information collected over the web. In this paper, big data paradigm has been studied in volunteer and grid system called Comcute that is optimized by a genetic programming scheduler. This scheduler can optimize load balancing and resource cost. Genetic programming optimizer has been applied for finding the Pareto solu-tions. Finally, some results from numerical...
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Partycypacja społeczeństwa informacyjnego w kształtowaniu przestrzeni współczesnego miasta/ Participation of the information society in the modern city creation
PublikacjaNiesłabnąca popularność narzędzi służących do kreowania map świadczy o zainteresowaniu społeczeństwa informacyjnego przestrzenią współczesnego miasta i zmianami w niej zachodzącymi. W artykule zostaną omówione nowe możliwości jakie daje ten rodzaj partycypacji. Podkreślony zostanie fakt, iż oddolne inicjatywy digitalizowania przestrzeni nie powinny być ignorowane przez profesjonalistów, gdyż tworzy się nowa przestrzeń dyskusji...
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Quantum entanglement
PublikacjaAll our former experience with application of quantum theory seems to say that what is predicted by quantum formalism must occur in the laboratory. But the essence of quantum formalism-entanglement, recognized by Einstein, Podolsky, Rosen, and Schrödinger-waited over 70 years to enter laboratories as a new resource as real as energy. This holistic property of compound quantum systems, which involves nonclassical correlations between...
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Methodological issues of functional safety and reliability assessment of critical systems in industrial hazardous plants
PublikacjaThe aim of this article is to identify and discuss some methodological issues that are of interest among functional safety specialists and experts after publication of the second edition of international standards IEC 61508 and IEC 61511, including the design and implementing the safety-related functions of higher safety integrity levels and protection layers. The basic role of safety-related systems is to reduce effectively and...
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Kształtowanie tożsamości na przykładzie małych miast województwa pomorskiego
PublikacjaSmall towns form an important element of the landscape, economy, both social and cultural life of our regions. Moreover, the way they develop determine regional indicators of the quality of life. These centers take today attempt to redefine its role and place in the spatial structures of the region, looking for new impulses and development opportunities to improve the living conditions of the local public. They have deeply divergent...
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A more colorful hat problem
PublikacjaThe topic is the hat problem in which each of n players is randomly fitted with a blue or red hat. Then everybody can try to guess simultaneously his own hat color by looking at the hat colors of the other players. The team wins if at least one player guesses his hat color correctly, and no one guesses his hat color wrong; otherwise the team loses. The aim is to maximize the probability of winning. We consider a generalized hat...
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Multimodal human-computer interfaces based on advanced video and audio analysis
PublikacjaMultimodal interfaces development history is reviewed briefly in the introduction. Some applications of multimodal interfaces to education software for disabled people are presented. One of them, the LipMouse is a novel, vision-based human-computer interface that tracks user’s lip movements and detect lips gestures. A new approach to diagnosing Parkinson’s disease is also shown. The progression of the disease can be measured employing...
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Towards systemic functional safety and security management in hazardous plants
PublikacjaThe aim of this article is to identify and discuss some issues related to functional safety and security management in hazardous industrial plants. The safety functions are to be realised using the electric / electronic / programmable electronic systems (E/E/PESs) or the safety instrumented systems (SISs) that are designed and operated respectively according to IEC 61508 and IEC 61511 requirements in life cycle. Although the role...
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Problems in designing and operating the functional safety solutions of higher integriity levels
PublikacjaThe aim of this article is to identify and discuss some problems that have been encountered in designing and operating the functional safety solutions of higher safety integrity levels (SIL 3 and SIL 4) in the light of analyses outlined in a new version of the international standard IEC 61508:2010. Examples of such solutions are the electric / electronic / programmable electronic systems (E/E/PESs) and the safety instrumented systems...
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Scenarios in the development strategies of larger cities in Poland
PublikacjaSummary: Planning prepares decisions and future actions. Therefore, future conditions should be considered in planning, in particular strategic planning, due to its long-term nature. To accomplish this, certain prognostic methods should be applied. A scenario method is seen as one of the most useful prognostic method, especially in cases when social and institutional behaviour plays a crucial role. The aim of the paper is an analysis...
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Safety Integrity Verification Issues of the Control Systems for Industrial Process Plants
PublikacjaThe aim of this article is to identify and discuss some issues that can be encountered in designing the industrial automation and control systems (IACS) for implementing safety functions. In a functional safety standard IEC 61511 for the process industry such systems are named the basic process control systems (BPCS) and the safety instrumented systems (SIS). In a generic functional safety standard IEC 61508 they are depicted as...
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A Cross-Team Collaborative Evaluation of a CRM System
PublikacjaThis paper presents an analysis of an usability evaluation a CRM (Customer Relationship Management) performed by a team composed of external usability experts jointly with a CRM staff. The evaluation process differed from a classical scheme known from former projects, including some new elements resulting from a specific context of this study. These novel elements resulted in reshaping the role of the CRM system and considering...
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Analysis of higher recombination orders in organic bulk heterojunction solar cells
PublikacjaRecently, it has been experimentally demonstrated that an order of nongeminate recombination exceeds two in some types of organic bulk heterojunction donor-acceptor structures. This result is different than for the case of bimolecular recombination described by Langevin theory. Although several theoretical explanations of this effect have been presented, the origin of higher recombination orders is still questionable. In this work,...
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EMC disturbances in connection of driving system
PublikacjaIt is known the steep voltage changes caused by IGBT frequency inverters may cause some electromagnetic problems in driving system. Special dU/dt type as well as sinusoidal filters are used in order to limit the level of the disturbances. The paper presents investigation results of EMC disturbances in inverter supplied induction motor. Experiments have proved that disturbances in current connection differ essentially. Important...
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Generalized Dold sequences on partially-ordered sets
PublikacjaDold sequences constitute an important class of integer sequences that play an important role in combinatorics, number theory, topology and dynamical systems. We generalize the notion of Dold sequence for the case of partially ordered sets and describe their properties. In particular we give two alternative descriptions of generalized Dold sequences: by some class of elementary sequences as well as by different...
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Degradation of tetracycline antibiotic utilizing light driven-activated oxone in the presence of g-C3N4/ZnFe LDH binary heterojunction nanocomposite
PublikacjaIn the present study, a binary heterojunction nanocomposite composed of graphitic carbon nitride (g-C3N4) and Zn/Fe-contained layered double hydroxide (ZnFe LDH) was employed as heterogeneous catalyst for the decomposition of tetracycline (TC) antibiotic utilizing Oxone and UV light irradiation. The sole use of g-C3N4/ZnFe LDH as adsorbent led to the negligible elimination of TC. In addition, the sole use of Oxone or UV (photolysis)...
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Poszukiwanie sankcji optymalnej w perspektywie projektu ustawy z dnia 7 lipca 2022 r. o zmianie ustawy Kodeks karny oraz niektórych innych ustaw. The search for the optimal sanction in the perspective of the draft act of 7 July 2022 amending the Penal Code and some other acts.
PublikacjaPolski ustawodawca opublikował w połowie września 2021 r. na stronie Rządowego Centrum Legislacji projekt gruntownej zmiany – między innymi – Kodeksu karnego. W dniu 7 lipca 2022 r. Sejm RP przyjął ww. projekt ustawy (druk sejmowy nr 2024). W zasadniczym stopniu nowelizacja - między innymi - zwiększa wysokość kar grożących za poszczególne przestępstwa. Ustawodawca – poprzez zabiegi legislacyjne –...
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Distance learning trends: introducing new solutions to data analysis courses
PublikacjaNowadays data analysis of any kind becomes a piece of art. The same happens with the teaching processes of statistics, econometrics and other related courses. This is not only because we are facing (and are forced to) teach online or in a hybrid mode. Students expect to see not only the theoretical part of the study and solve some practical examples together with the instructor. They are waiting to see a variety of tools, tutorials,...
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Restoration and preservation of the reinforced concrete poles of fence at the former Auschwitz concentration and extermination camp
PublikacjaThe objective of this study was to assess the present state of the reinforced concrete poles of fence at the former Auschwitz I and Auschwitz II-Birkenau concentration and extermination camp. The poles were subjected to renovation about 10 years ago. After this time some deficiencies of applied renovation method were noticed. Cracks appeared between fresh and original part of concrete cover. Analysis of the reasons of these failures...
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Restoration and preservation of the reinforced concrete poles of fence at the former Auschwitz concentration and extermination camp
PublikacjaThe objective of this study was to assess the present state of the reinforced concrete poles of fence at the former Auschwitz I and Auschwitz II-Birkenau concentration and extermination camp. The poles were subjected to renovation about 10 years ago. After this time some deficiencies of applied renovation method were noticed. Cracks appeared between fresh and original part of concrete cover. Analysis of the reasons of these failures...
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Model and laboratory simulation of a induction motor for diagnostic purposes
PublikacjaStatistics say that bearings are this part of induction motors which is most susceptible to damage. The equipment employed for bearing diagnostics usually makes use of vibrations as the criterion for technical condition of the bearings. A faulty bearing results in additional motor vibrations. They are reflected in the harmonic content of stator currents. In certain operating conditions the current signal is the sole source of information...
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The green waterfront of a city. Where are the limits of good planning? Gdansk case
PublikacjaThe aim of the article is to present the role of green public areas of waterfronts in shaping the image of cities, and the threats to such landscape which may be caused by wrong planning decisions. The case study of Gdansk sea-shore area in Poland is presented as an example to illustrate the values and potential of the waterfront landscape which can be easily destroyed by inadequate spatial development. Some theoretical studies...
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Smart Virtual Product Development (SVPD) System to Support Product Inspection Planning in Industry 4.0
PublikacjaThis paper presents the idea of supporting product inspection planning process during the early stages of product life cycle for the experts working on product development. Aim of this research is to assist a collaborative product development process by using Smart Virtual Product Development (SVPD) system, which is based on Set of Experience Knowledge Structure (SOEKS) and Decisional DNA (DDNA). The proposed system is developed...
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Magnetic field effects in dye-sensitized and organic solar cells
PublikacjaThe charge recombination and exciton dissociation are generally recognized as the basic electronic processes limiting the efficiency of photovoltaic devices. The aim of this thesis is to understand the electronic processes limiting the operation of efficient solar cells with particular emphasis on the role of electronic states endowed with magnetic dipole moment. The research work is divided into two parts. The first part deals...
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Study of the Anti-Staphylococcal Potential of Honeys Produced in Northern Poland
PublikacjaThe antimicrobial activity of 144 samples of honeys including 95 products from apiaries located in Northern Poland was evaluated. The antibacterial activity of those natural products, their thermal stability, and activity in the presence of catalase was investigated by microdilution assays in titration plates. The MTT assay was performed for the determination of anti-biofilm activity. Spectrophotometric assays were used for the...
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Experience marketing in the service of the “secular religion” of big tech
PublikacjaThe article proposes an interpretation of the meaning of experience marketing as a tool in the process of sacralisation of products, and in a broader context – the so-called secular religion accompanying some contemporary big tech organizations. The article is of theoretical nature and the authors have intended to explain how big tech corporations, in line with the concept of experience marketing (digital platforms, in particular),...
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Spurring the community involvement in planning - lessons from post-socialist cities
PublikacjaPublic participation and community involvement in planning processes is – in general – not a new topic for contemporary planners. But in many parts of the world – including the post-socialist countries like Poland or Russia – we can still face the lack of understanding of importance of proper community involvement in planning and development processes. Situation in these countries is significantly different from both highly-developed...
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Cavitation based cleaner technologies for biodiesel production and processing of hydrocarbon streams: A perspective on key fundamentals, missing process data and economic feasibility – A review
PublikacjaThe present review emphasizes the role of hydrodynamic cavitation (HC) and acoustic cavitation in clean and green technologies for selected fuels (of hydrocarbon origins such as gasoline, naphtha, diesel, heavy oil, and crude oil) processing applications including biodiesel production. Herein, the role of cavitation reactors, their geometrical parameters, physicochemical properties of liquid media, liquid oxidants, catalyst loading,...
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Selected concentration techniques for gas chromatographic analysis of environmental samples
PublikacjaThe paper describes the role and tasks of environmental analysis and monitoring. It emphasises the leading role played by gas chromatography, especially when coupled with suitable sample preparation. This is demonstrated by some literature evidence and mainly by the author's original work on the design of sample preparation apparatus and development of GC-based methods of determination of a wide variety of organic pollutants in...