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Search results for: IMPURITIES IN PHARMACEUTICAL PRODUCTS
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Formation of OH Radicals as Evidence of Intramolecular Hydrogen Migration in Cation-Induced Dissociation of Furan Molecules
PublicationWe present the experimental results on a hydrogen atom migration preceding fragmentation of the furan molecules induced by the H3+ and C+ impact. The excited OH(A2Σ+) radical has been detected among the furan decomposition products using collision-induced emission spectroscopy. However, the OH moiety is absent in the furan ring skeleton, so detecting the OH(A2Σ+→X2Π) luminescence indicates the intramolecular H atom relocation prior...
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Integrated Experimental and Theoretical Approach for Efficient Design and Synthesis of Gold-Based Double Halide Perovskites
PublicationApplied cutting-edge electronic structure and phonon simulations provide a reliable knowledge about the stability of perovskite structures and their electronic properties, which are crucial for design of effective nanomaterials. Gold is one of the exceptional elements, which can exist both as a monovalent and a trivalent ion in the B site of a double perovskite such as A2BI BIIIX6. However, until now, electronic properties of Cs2AuI AuIIIX6...
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Charakterystyka odcieków powstających w aspekcie wyboru metody ich oczyszcania
PublicationArtykuł obejmuje analizę odcieków generowanych w zakładach utylizacji odpadów w aspekcie ich ilości i jakości oraz możliwości oczyszczania/zagospodarowania, ze szczególnym zwróceniem uwagi na metody biologiczne, najbardziej przyjaznej środowisku. Ponad trzyletnie badania prowadzono na dwóch obiektach zlokalizowanych w woj. pomorskim, gdzie pobierano próbki ścieków technologicznych, powstających podczas sortownia oraz kompostownia odpadów...
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Reminiscencje z 18. Międzynarodowego Seminarium Obróbki Drewna w Vancouver. Cz. IV: Kanadyjska gospodarność surowcem.
PublicationPrzedstwaiono ogólną charakterystykę dwu zakładów usytuowanych w Pentincton (Kolumbia Brytyjska, Kanada): Canwood Furniture Inc. oraz Structurlam Products Ltd.. Pierwszy z nich jest producentem mebli litych głównie z drewna sosnowego, są to meble typu R.T.A. (ready to assamble), tj. meble do samodzielnego montażu. Drugi z kolei zakład produkuje elementy konstrukcyjne z drewna klejonego warstwowego. Artykuł kończy serię artykułów...
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Emulsifi ers from renewable materials: an eco-friendly synthesis and properties
PublicationThe focus of this study was the preparation of novel bio based polyglycerol emulsifiers characterized by a one pot synthesis, thus by modified properties with respect to interfacial activity and effectiveness as emulsion stabilizers. The final products of the esterification process, carried out in the presence of carboxylates were used directly as emulsifiers (without purification or fractionation). Polyglycerol emulsifiers obtained...
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The Pomerania Design Faktory as an Example of 50+ Entrepreneurship Promotion
PublicationThe article presents one of the programmes carried out by The Gdańsk Entrepreneurs' Foundation and The Gdansk Labor Office in 2013/14, dedicated to seniors. It is a great example of an innovative project aimed at the activation of individuals aged 50+ by using their own talents and interests in business. It also shows the results of intergenerational cooperation because the trainers — especially the designers — were much younger...
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Geometric Algebra Model of Distributed Representations
PublicationFormalism based on GA is an alternative to distributed representation models developed so far-Smolensky's tensor product, Holographic Reduced Representations (HRR) and Binary Spatter Code (BSC). Convolutions are replaced by geometric products, interpretable in terms of geometry which seems to be the most natural language for visualization of higher concepts. This paper recalls the main ideas behind the GA model and investigates...
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Pilot- scale plant for material recycling of whole waste tires
PublicationContinously growing demad for all kinds of vehicles and general tendency to regular exchange of tires are causing growth of scrap tires which need management. A risings of large quantities of used rubber products, especially used tires has been increasing every year in Poland, in 2006 it was 160 thousand. The waste management and recycling of used tires become a major environmental problem. It is worth noticing that tires which...
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Studies on Treatment of Bitumen Effluents by Means of Advanced Oxidation Processes (AOPs) in Basic pH Conditions
PublicationThe paper presents the results of studies on chemical treatment of effluents from production of bitumen of petroleum origin. Due to the presence of sulfide ions, the pH of these effluents is strongly alkaline. Several Advanced Oxidation Processes (AOPs) were studied, including the use of hydroxyl and sulfate radicals oxidants, the hydrodynamic cavitation as well as sonocavitation. The best processes allow to obtain 45% reduction...
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Studies on treatment of bitumen effluents by means of Advanced Oxidation Processes (AOPs) in basic pH conditions
PublicationThe paper presents the results of studies on chemical treatment of effluents from production of bitumen of petroleum origin. Due to the presence of sulfide ions, the pH of these effluents is strongly alkaline. Several Advanced Oxidation Processes (AOPs) were studied, including the use of hydroxyl and sulfate radicals oxidants, the hydrodynamic cavitation as well as sonocavitation. The best processes allow to obtain 45% reduction...
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Smart Innovation Engineering System - A Tool for Facilitating Product Innovation Process
PublicationFor the survival and prosperity of the manufacturing unit, entrepreneurs need to find out new ideas that can be implemented in the products leading to innovation. The current study employs a systematic approach for product innovation. In this approach past experiences based on innovation decisions are stored and recalled during the innovation problem solving process. Implementing this system in the process of product innovation...
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The innovative exploitation of Brassica vegetables in the production of quality food for health. From lab bench to field and fork.
PublicationThe specific chemical composition of vegetables belonging to Brassicaceace , as regard both nutrients and non-nutrients, renders them particularly suitable for the health food production chain. The ability of these plants to accumulate heavy metals may be utilised for phytoremediation of arable soils, but also as a vehicle to fortify foods in micronutriens such as selenium. The bioactive organosulfur compounds, especially glucosinolates...
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Reactive Processing and Functionalization of Ground Tire Rubber
PublicationThe dynamic development of the automotive industry resulted in a sig- nificant increase in rubber wastes, especially end-of-life tires, which are a serious threat to the natural environment and human health. This situation has enforced the industry and academic research groups to search new and cost-effective methods for recycling waste tires. In this field of research, reactive processing and functionaliza- tion seem to be a...
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Sulfurization of phosphanylphosphinidene ligand: Access to phosphinothioyltrithiophosphonato platinum(II) complexes
PublicationThe reactivity of phosphanylphosphinidene Pt(0) complexes [DppePt(η2-P–PtBu2)] (1) and [(pTol3P)2Pt(η2-P–PtBu2)] (2) toward sulfur was studied. Reactions of 1 and 2 with an excess of sulfur led to the formation of the first transition metal complexes 3 and 4 with phosphinothioyltrithiophosphonato ligands with the formula [tBu2P(=S)–P(=S)S2]2-. In contrast to previous reports on the phosphanylphosphinidene moiety sulfurization,...
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Solvent Screening for Solubility Enhancement of Theophylline in Neat, Binary and Ternary NADES Solvents: New Measurements and Ensemble Machine Learning
PublicationTheophylline, a typical representative of active pharmaceutical ingredients, was selected to study the characteristics of experimental and theoretical solubility measured at 25 °C in a broad range of solvents, including neat, binary mixtures and ternary natural deep eutectics (NADES) prepared with choline chloride, polyols and water. There was a strong synergistic effect of organic solvents mixed with water, and among the experimentally...
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CONDITIONING FACTORS OF INDUSTRY-UNIVERSITY COOPERATION FROM THE PERSPECTIVE OF ENTERPRISES
PublicationThe cooperation between enterprises and universities varies in terms of character and intensity. Bearing in mind the potential represented by both parties, its low intensity is still noticed, and consequently, the lack or incomplete use of opportunities resulting from this cooperation. Current factors of industry-university cooperation were identified from the perspective of companies from biotechnology and pharmaceutical...
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Quantification of Compatibility Between Polymeric Excipients and Atenolol Using Principal Component Analysis and Hierarchical Cluster Analysis
PublicationAn important challenge to overcome in the solid dosage forms technology is the selection of the most biopharmaceutically efficient polymeric excipients. The excipients can be selected, among others, by compatibility studies since incompatibilities between ingredients of the drug formulations adversely affect their bioavailability, stability, efficacy, and safety. Therefore, new, fast, and reliable methods for detecting incompatibility...
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Enhanced photocatalytic activity of accordion-like layered Ti3C2 (MXene) coupled with Fe-modified decahedral anatase particles exposing {1 0 1} and {0 0 1} facets
PublicationNew composites consisting of decahedral anatase particles exposing {001} and {101} facets coupled with accordion-like layered Ti3C2 with boosted photocatalytic activity towards phenol and carbamazepine degradation were investigated. The photocatalysts were characterized with X-ray diffraction (XRD), diffuse reflectance spectroscopy (DR/UV–Vis), Brunauer-Emmett-Teller (BET) specific surface area, Raman spectroscopy, scanning electron...
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Pharmaceuticals and another groups of emerging contaminants: Occurrence and sources in Admiralty Bay (King George Island, Maritime Antarctica)
PublicationEveryday live activities may introduce a wide range of chemicals into wastewater systems. In this study presence of selected types of pharmaceuticals from cardiovascular system group, nervous and muscolo-skeleton system group, antimicrobial agents, genitourinary and sex hormones were tested in the wastewater from H. Arctowski Antarctic station. Moreover, the receiver of discharged wastewater (Admiralty Bay) were also studied. Considering...
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Problemy z powłokami antykorozyjnymi na elementach wyposażenia obiektów mostowych
PublicationOpisano problem wadliwości zabezpieczenia antykorozyjnego w zakresie malarskich powłok ochronno-dekoracyjnych wykonywanych na stalowych elementach barier zabezpieczonych uprzednio poprzez ocynkowanie metodą zanurzeniową na gorąco. Wykorzystując przykłady pochodzące z różnych obiektów przedstawiono powtarzający się problem delaminacji powłok malarskich, niezależny od rodzaju zastosowanych wyrobów lakierniczych oraz znacznego rozwoju...
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Problemy z powłokami antykorozyjnymi na elementach wyposażenia obiektów mostowych
PublicationPrzedstawiono problem wadliwości zabezpieczenia antykorozyjnego w zakresie malarskich powłok ochronno - dekoracyjnych wykonywanych na stalowych elementach barier zabezpieczonych uprzednio poprzez ocynkowanie metodą zanurzeniową. Wykorzystując przykłady pochodzące z różnych obiektów przedstawiono powtarzający się problem delaminacji powłok malarskich, niezależny od rodzaju zastosowanych wyrobów lakierniczych oraz znacznego rozwoju...
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Customer Assessment of Brand Valuation and Social Media
PublicationThe research problem engaged in this article is to determine whether contemporary consumers are able to assess brand equity in the overabundance of brands and products with similar features and qualities. The author argues that in the existing circumstances when differences between brands become insignificant the consumer is not capable of assessing their equity adequately. In order to verify the thesis the author has accepted...
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Microwave radiation in the synthesis of urethane prepolymers
PublicationThis paper describes the use of microwave radiation in the synthesis of urethane prepolymers in bulk (without solvent). The prepolymers were synthesized using 1,6-hexamethylene diisocyanate (HDI) and poly (ε-caprolactone) diol (PCL) at a molar ratio of 4:1. The reaction was carried out without a catalyst in the reactor with a conventional heating system (oil bath) or in the microwave reactor (MW Reactor NOVA 09) at temperatures...
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Hydroxyl and sulfate radical-based degradation of ciprofloxacin using UV-C and/or Fe2+-catalyzed peroxymonosulfate: Effects of process parameters and toxicity evaluation
PublicationCiprofloxacin (CIP) is a valuable antibiotic and discharged in huge quantities in aquatic environment. Different •OH and SO4•−-based advanced oxidation technologies (AOTs), e.g., Fe2+/PMS, UV-C/PMS, and UV-C/Fe2+/PMS are developed for treatment of CIP. The removal of CIP by Fe2+/PMS, UV-C/PMS and UV-C/Fe2+/PMS was 63, 77, and 87 %, respectively, under identical conditions which showed better performance of UV-C/Fe2+/PMS. The UV-C/Fe2+/PMS...
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Biorefinery Approach for H2 and Acids Production Based on Uncontrolled pH Fermentation of an Industrial Effluent
PublicationIn this work, the feasibility of uncontrolled pH acidogenic fermentation of industrial organic effluent from corn-bioethanol production was studied and modelled by using a Monod-based mathematical model. In order to do that, several tests were carried out at different initial pH values, ranging from 4 to 6. The experimental data showed a pH reduction during the fermentation process due to the generation of short-chain acids. When...
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Nanofiltration-Assisted Concentration Processes of Phenolic Fractions and Carotenoids from Natural Food Matrices
PublicationIn new food formulations, carotenoids and phenolic compounds are likely to be the most sought after food ingredients according to their bioactivity, nutraceutical, nutritional value, and compatibility properties once incorporated into food formulations. Such solutes are naturally present in many plant-based sources, and some portions are directly consumed when enriching food products and formulations; however, some portions, which...
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Applicability of edible Candelilla wax composite blended with Bryophyllumpinnatum extract to prolong shelf life of fruits/vegetables
PublicationCandelilla wax (CW) is a natural lipid source that can be used to make biodegradable and edible coatings and films for fruits. However, CW alone does not provide sufficient antimicrobial and antioxidant properties to prevent microbial spoilage and oxidative deterioration of fresh products. This study aims at evaluating the applicability of CW blended with Bryophyllum pinnatum extract (BPE), a plant with medicinal and phytochemical...
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Application of gas chromatographic data and 2D molecular descriptors for accurate global mobility potential prediction
PublicationMobility is a key feature affecting the environmental fate, which is of particular importance in the case of persistent organic pollutants (POPs) and emerging pollutants (EPs). In this study, the global mobility classification artificial neural networks-based models employing GC retention times (RT) and 2D molecular descriptors were constructed and validated. The high usability of RT was confirmed based on the feature selection...
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Phospholipids as potential prevention factor in carcinogenesis
PublicationPhospholipids are a group of complex lipids, which can be used in cancer chemoprevention. Glicerophospholipids are composed of fatty acids esterified to a glycerol backbone, a phosphate group and a hydrophilic residue such as: cho- line, ethanoloamine, serine or inositol. In the sn-2 position of glicerophospholipid usually there are unsaturated fatty acids, i.e. linolenic acid, while in the sn-1 position more typi- cal are saturated...
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Doing Well by Doing Good- CSR in a Global Context
PublicationNowadays, there is a general understanding that stakeholders are crucial for the successful enterprise. There is also a need to think about Corporate Social Responsibility (CSR) in a global context. Never before corporations enjoyed so much power and authority. Corporations need to evolve, re-think their strategies and change their processes accordingly. However, as of now, there is no agreed way of measuring overall sustainability...
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ISLAMIC TAKAFUL: CZY SKUTECZNIE ZASTĄPIŁ UBEZPIECZENIA KOMERCYJNE? : ISLAMIC TAKAFUL: HAS IT SUCCESSFULLY SUBSTITUTED CONVENTIONAL INSURANCE?
PublicationIslamic finance is a fast developing sector mainly present in the Middle East, South-East Asia, Central Asia and to a smaller extent in Africa and Central Europe. Together with the rebirth of Islam in the second half of the 20th century, Islamic finance tends to cover the economic needs of all Muslims (including insurances). The Islamic finance system is based on several principles including three main prohibitions: Gharar (deceptive uncertainty),...
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Waste tire rubber devulcanization technologies: State-of-the-art, limitations and future perspectives
PublicationWaste tires management is a serious and global environmental problem. Therefore, searching for low-cost and industrial-scale applicable tire recycling methods is gaining more and more attention. Waste tire rubber is valuable source of secondary raw materials for the circular economy and current trends indicate that application of waste rubbers during manufacturing value-added products should increase in near future. Sustainable...
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Provenance studies on Late Neolithic amber ornaments from North-East Poland
PublicationThe area of North-East Poland was in prehistory, and still is today, an area with easy access to amber as a raw material, as is evidenced in part by numerous Late Neolithic (3rd millennium) amber workshops located in the Gulf of Gdańsk and Żuławy Wiślane (Vistula Fens). Given this fact, it is surprising that only a few finished amber products have been recovered from this area. Among them are unique ornaments from the Late Neolithic...
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Properties comparison of rubber and three layer PTFE-NBR-bronze water lubricated bearings with lubricating grooves along full bush circumference based on experimental tests
PublicationWater lubricated bearings have been in industrial use for well over a century. During the last decade their traditional range has been expanded with new, modern products. Despite that fact, certain solutions continue to employ the standard rubber bearing with lubricating grooves located along entire bush circumference. The work presents experimental research conducted on comparable sliding bearings with lubrication grooves along...
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Use of Sensory Analysis Methods to Evaluate the Odor of Food and Outside Air
PublicationSensory analysis is applied in many areas of daily life. It is used to carry out the sensory evaluation of foodstuffs or other products and to evaluate the properties of odors present in the environment. The authors attempt to summarize the knowledge on the classification and application of sensory analysis methods to evaluate the odor nuisance of air, which allows the identification of sensory impressions and determination of...
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One Europe, one product, two prices - the price disparity in the EU
PublicationThe price dispersion in the European Union in the last fifteen years (1990-2005) is analysed. The analysis of price convergence is examined on aggregate and disaggregate levels. The macro approach is based on Comparative Price Level index calculated as the ratio between PPPs and exchange rate. The disaggregate analysis utilizesactual prices of 148 individual products sold in the 15 capital cities of the EU. The calculations comprise...
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The content of high-intensity sweeteners in different categories of foods available on the Polish market
PublicationThe objective of this study was to measure the concentrations of nine high-intensity sweeteners (acesulfame-K, aspartame, alitame, cyclamate, dulcin, neohesperidin DC, neotame, saccharin and sucralose) in different categories of food available on the Polish market. Over 170 samples of different brands of beverages, yoghurts, fruit preparations, vegetable preserves and fish products were analysed using an analytical procedure based...
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Determination of the substances potentially allergenic in water
PublicationPersonal care chemicals are continuously released into environment through domestic and industrial wastewater, causing adverse effects on human health. Their presence can be detected in different environmental compartments. A group of chemicals included in most personal care products are the allergen fragrances. In the present work, simple and rapid methodology based on ultrasound-assisted emulsification-microextraction (USAEME)...
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Modal analysis of cylindrical steel tanks
PublicationCylindrical steel tanks are very popular structures used for storage of products of chemical and petroleum industries. Their safety and reliability is crucial because any failure could have serious consequences. The aim of present paper is to show the results of the first phase of investigation of seismic behaviour such structures. Modal analysis using Finite Element Method (FEM) for three models of real tanks used in Poland has...
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Optimization model of agile team’s cohesion
PublicationTeam’s cohesion is one of the most important factors of IT project execution effectiveness. Optimization of team’s cohesion gives the possibility of reducing the risk of project failure. It also allows to increase the teamwork efficiency and thus optimize time of tasks execution, increase the guarantee of maintaining the scope of the project and the chance of achieving a given level of products quality. This article presents determination...
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Services Marketing Influence On Marketing Theory Evolution,
PublicationThe discovery of differences between tangible goods and services in the 1970s was one of the most landmark moments in the history of marketing with an emphasis being shifted to the need for using different/diversified marketing activities while dealing with various industries and types of products. The objective of this article is to briefly characterise the evolution of the marketing thought and to present the crucial influence...
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On thio‐substituted N‐heterocyclic arsines
PublicationMetathesis of N-heterocyclic chloroarsines with sulfur-based nucleophiles furnished thio-substituted 1,3,2-diazarsolidines and 1,3,2-diazarsolenes. Crystallographic and NMR spectroscopic studies revealed that a thiocyanato-diazarsolene exhibits a salt-like structure composed of weakly interacting thiocyanate and arsenium ions, while the remaining products formed neutral molecules. The structural data indicate that the heterocyclic...
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Efficient synthesis and antifungal investigation of nucleosides’ quaternary ammonium salt derivatives
PublicationQuaternary ammonium salts are a group of compounds with diverse biological properties, the most important of which are their antiviral, antibacterial, and antifungal activities. The quaternization reactions of 5'-O-tosyl derivatives of uridine and thymidine with triethylamine, trimethylamine, 4-(N ,N -dimethylamino)pyridine, 2-methylpyridine, and pyridine are described in this article. Two of the synthesized compounds are exceptional...
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Optical Spectroscopic Studies of Tetrahydrofuran Fragmentation Induced by Collisions with Dihydrogen Cations
PublicationCollisions of dihydrogen cations with tetrahydrofuran molecules have been studied. Luminescence spectra and the emission functions of the excited products at projectile energies ranging from 8 to 1000 eV have been measured using collision-induced emission spectroscopy. The recorded spectra are dominated by the atomic lines of the hydrogen Balmer series, whose intensities decrease more quickly than derived by the quantum-theoretical...
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Synteza, struktura chemiczna i właściwości bezizocyjanianowych poliuretanów otrzymywanych z wykorzystaniem CO2 oraz surowców pochodzenia naturalnego.
PublicationZ uwagi na wciąż rosnącą świadomość proekologiczną, politykę zrównoważonego rozwoju, a także nurt zielonej chemii wiodącym trendem w przemyśle tworzyw sztucznych jest poszukiwanie alternatywnych metod otrzymywania materiałów polimerowych. Komercyjnie poliuretany otrzymywane są w wyniku reakcji poliaddycji di- lub poliizocyjanianów z poliolami i małocząsteczkowymi przedłużaczami łańcucha. Z uwagi na niekorzystne właściwości diizocyjanianów,...
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4D Reconstruction and Visualisation of Krakow Fortress
PublicationThe specific aim of the European project named "Cultural Heritage Through Time" (CHT2) and reported in this paper is to fully integrate the fourth dimension (4D) into Cultural Heritage studies for analysing structures and landscapes over time. Krakow-the Fortress City (Poland) is the one of four case studies of the CHT2, which are used for the time varying reconstruction, analysis, visualization, and preservation. The goal of...
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Stimulated by cyclodextrins high yield synthesis of azocrown analogues comprising pyrrole or imidazole residues
PublicationThe influence of cyclodextrins (CDs) on the formation of azocrown ethers comprising pyrrole, imidazole and substituted imidazole has been studied. Pyrrole, imidazole, 2-methyl-, 4-methyl- and 4-phenylimidazole were coupled with bisdiazonium salts derived from bis-1,5-(2-aminophenoxy)-3-oxapentane or bis-1,8-(2-aminophenoxy)-3,6-dioxaoctane to form macrocyclic compounds with two azo units. The syntheses were performed under standard...
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Importance of artificial intelligence to support the process of anaerobicdigestion of kitchen waste with bioplastics / Znaczenie sztucznej inteligencji we wspomaganiu procesu beztlenowej fermentacji odpadów kuchennych zawierających bioplastiki
PublicationArtificial intelligence (AI) and machine learning were used to obtain more effective methods for conducting the digestion process and achieving final products. Data acquisition was carried out by an automatic monitoring and anal. research. The knowledge describing the anaerobic digestion process was summarized in the form of rules: IF (premise) THEN (conclusion). The compiled set of rules created a knowledge base of the expert...
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Geotechnical Aspects of Dike Construction Using Soil-Ash Composites
PublicationAn analysis of using of anthropogenic materials, mainly ashes from Coal Combustion Products (CCP), for dike construction is shown. Perspectives of anthropogenic materials application in geotechnical engineering and their advantages in sense of the carbon dioxide reduction are discussed. According to regulations of Kioto Protocol 2005 and EU agreement “Energy Roadmap 2050” recycled materials have higher usage priority than natural...
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Influence of the addition of citric acid on the physico-chemical properties of poly(sorbitol sebacate-co- butylene sebacate)
PublicationThe article presents the results of the physicochemical properties of poly(sorbitol sebacate- co-butylene sebacate) (PSBS) obtained with 0.25; 0.5; 0.75; 1 mol of citric acid (KC). It was shown that PSBS obtained with 0.25 and 0.5 mol KC is characterized by the most optimal mechanical and thermal properties. As a result of the study, it was found that the use of sorbitol and citric acid allows obtaining ester materials with...