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Design of rail-track geometric systems by satellite measurement
PublicationW pracy przedstawiono rezultaty zastosowania ciągłych pomiarów satelitarnych toru kolejowego, z antenami zainstalowanymi na poruszającym się pojeździe szynowym. Wykazano, że zastosowana pilotażowo technika pomiarowa umożliwia bardzo precyzyjne określenie podstawowych danych do projektowania modernizacji linii kolejowej (kierunków głównych trasy i jej kąta zwrotu), a także - ze stosunkowo niewielkim błędem - współrzędnych istniejącej...
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Extended micropolar approach within the framework of 3M theories and variations thereof
PublicationAs part of his groundbreaking work on generalized continuum mechanics, Eringen proposed what he called 3M theories, namely the concept of micromorphic, microstretch, and micropolar materials modeling. The micromorphic approach provides the most general framework for a continuum with translational and (internal) rotational degrees of freedom (DOF), whilst the rotational DOFs of micromorphic and micropolar continua are subjected...
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Extremal thermal loading of a bifurcation pipe
PublicationThe subject of considerations is a spherical bifurcation pipe of a live steam made of steel P91, which is an element of a block of coal-fired power plant working with a 18K370 turbine. As experience shows, it is a very sensitive element of the boiler pipelines. An extreme work scenario for such a block has been adopted, in which the turbine is shutting down to a warm state three times in 24 hours. This is an action dictated by...
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Banking concentration in the Baltic and Western Balkan states — selected issues
PublicationResearch background: In a rapidly changing economic environment companies deepen their cooperation, which entails in all sectors of the economy. The progressive increase in market concentration, especially in the banking sector, is caused by various reasons. Purpose of the article: The purpose of this article is to compare the tendencies within market structures in few countries which origin from similar political systems and...
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RAPORT-EKSPERTYZA Z POMIARÓW DRGAŃ LINII WAŁÓW NA JEDNOSTCE ORP „PIORUN”
PublicationEkspertyza diagnostyczna dotycząca stanu technicznego lini transmisji mocy (linii wałów) opracowana na podstawie przeprowadzonych pomiarów drgań. Pomiary prędkości i przyspieszeń drgań generowanych przez węzły konstrukcyjne linii wałów okrętowego układu napędowego wykonano po naprawie głównej napędu okrętu w stoczni „NAUTA”, w celu określenia jego stanu dynamicznego. Rejestrację drgań przeprowadzono w: • płaszczyźnie pionowej (V)...
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Ergonomic Aspects of Transport of Patient through the Operating Theatre
PublicationOne of the most crucial decisions to be made while designing and re-modernizing an operating theatre is selecting a method of transporting the patient through the hospital’s spatial arrangement. This decision, while irrelevant at first thought, implies numerous project and functional consequences. Designing an operating theatre within a hospital is related to numerous specialist requirements with an aim of minimizing the risk of...
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Programowo-sprzętowa platforma symulacyjna - Hardware In the Loop - zaawansowanego układu sterowania poziomem wody w pionowej wytwornicy pary elektrowni jądrowej
PublicationW artykule przedstawiono koncepcję programowo-sprzętowej platformy symulacyjnej wykorzystującej technikę symulacji w pętli sprzętowej HIL (ang. Hardware In The Loop simulation), wykorzystanej dla potrzeb projektowania i weryfikacji w czasie rzeczywistym (ang. Real Time) zaawansowanych algorytmów sterowania poziomem wody w pionowej wytwornicy pary elektrowni jądrowej. Jej głównymi elementami sa: środowisko czasu rzeczywistego Matlab/Simulink...
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Comparative assessment of two extraction procedures for determination of bioactive compounds in some berries used for daily food consumption
PublicationTwo extractions with methanol and water were used to determine the antioxidant and binding properties of some berries as a supplement to food. Fluorometry, FTIR spectra and radical scavenging assays were used for characterisation of bioactive compounds (polyphenols, flavonoids, flavanols and tannins) and the levels of their antioxidant activities (AAs). The contents of bioactive compounds and AAs in water and methanol polyphenol...
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PRINCIPLES OF ARTIFICIAL INTELLIGENCE APPLICATION IN CONTROL OF THE ENTERPRISE
PublicationThe implementation of the tasks of evaluating historical financial information, the control or audit of business activities are based primarily on professional judgments about the object of study of a professional accountant or auditor. Their findings are drawn on the basis of the study of documents, the use of audit evidence, risk assessment, etc. There is always a probability (and rather high) that professional judgment will...
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The Interaction of Heptakis (2,6-di-O-Methyl)-β-Cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity
PublicationOne tetracyclic antidepressant, mianserin hydrochloride (MIA), has quite significant side effects on a patients’ health. Cyclodextrins, which are most commonly used to reduce the undesirable features of contained drugs within their hydrophobic interior, also have the potential to alter the toxic behavior of the drug. The present paper contains investigations and the characteristics of interaction mechanisms for MIA and the heptakis...
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Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration
Publicationhis paper addresses the potential application of flexible thermoplastic polyurethane (TPU) and poly(lactic acid) (PLA) compositions as a material for the production of antibacterial wound dressings using the Fused Filament Fabrication (FFF) 3D printing method. On the market, there are medical-grade polyurethane filaments available, but few of them have properties required for the fabrication of wound dressings, such as flexibility...
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The Impact of Different Drying Methods on the Metabolomic and Lipidomic Profiles of Arthrospira platensis
PublicationDrying is an inseparable part of industrial microalgae production. In this work, the impacts of eight different drying methods on the metabolome and lipidome of Arthrospira platensis were investigated. The studied drying methods were freeze drying (FD), sun drying (SD), air drying at 40 and 75 °C (AD′ and AD″), infrared drying at 40 and 75 °C (IRD′ and IRD″), and vacuum drying at 40 and 75 °C (VD′ and VD″). Results gathered by...
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Closing the loop: Upcycling secondary waste materials into nanoarchitectured carbon composites for the electrochemical degradation of pharmaceuticals
PublicationIn this study, we demonstrated the application of electrochemical oxidation as a safer and cleaner technology for minimizing the impact of pharmaceuticals in wastewaters, simultaneously mediated by upcycled secondary waste materials (SWMs)-derived electrodes, to further reduce their environmental impact. The modularity, scalability, ease of operation and reliability make electrochemical oxidation an ideal process for the destruction...
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Assessment of the application of CEM III with exposed aggregate as an alternative to CEM I for road pavements
PublicationThe article presents a results of study on the impact of replacing CEM I SR3/NA by CEMIII/A LH/HSR/NAon the mechanical properties and durability of pavement concrete with exposed aggregate. Was used granite aggregate and washed sand. Water/cement () ratio in the tested concretes constituted 0.35 and 0.4 and part of the cement was replaced with a 5% addition of natural pozzolana – zeolite. Compressive strength tests were performed...
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The protocol for using elastic wall model in modeling blood flow within human artery
PublicationMedical diagnostic tools will play a major role in the future for an effective patient treatment and reduction their mortality, related to the cardiovascular system diseases (CVDs). There is an urgent need for developing diagnostic procedure to be robust, reliable, accurate and efficient, in the framework of a paradigm shift. Application of numerical techniques is seen as a perspective tool for such purpose. Nevertheless, existing...
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Enhancing Economic Development Through ICT-Based Governance: Evidence for Developing Countries
Publicationhis shows novel empirical evidence on how e-government solutions enhance the emergence of inclusive societies, increase institutional quality, and through that channels dynamize economic development in developing countries. With this aim we examine digital development inequalities adopting 2 core ICT indicators: mobile cellular telephony and Internet users; and gross per capita income and Human Development Index to show the level...
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Machine learning-based prediction of residual drift and seismic risk assessment of steel moment-resisting frames considering soil-structure interaction
PublicationNowadays, due to improvements in seismic codes and computational devices, retrofitting buildings is an important topic, in which, permanent deformation of buildings, known as Residual Interstory Drift Ratio (RIDR), plays a crucial role. To provide an accurate yet reliable prediction model, 32 improved Machine Learning (ML) algorithms were considered using the Python software to investigate the best method for estimating Maximum...
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Experimental and theoretical studies on the Sulfamethazine-Urea and Sulfamethizole-Urea solid-liquid equilibria
PublicationThe miscibility of active pharmaceutical ingredients with excipients is an important aspect in pharmaceutical technology protocols. In this study, the differential scanning calorimetry (DSC) was used for Sulfamethazine-Urea (SI–U) and Sulfamethizole-Urea (SO–U) solid-liquid phase diagrams determination. Both sulfonamides form simple binary eutectics with Urea. The lack of new co-crystal phase formation was confirmed by inspection...
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Właściwości elektryczne szkło-ceramiki zawierającej ferroelektryczną fazę BiV
PublicationKompozyty szklano - ceramiczne zawierające nanokryształy posiadają właściwości fizyczne, które nie są możliwe do uzyskania w innych materiałach. Dzięki możliwości wytworzenia szkło - ceramik posiadających kryształy o różnej wielkości (nano, mikro...) i różnorodnego typu, można w istotny sposób kontrolować właściwości elektryczne takich materiałów. Stała dielektryczna faz ferroelektrycznych jest bardzo wrażliwa na zmiany rozmiarów...
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Chemical Control of SrLi(Al1–xGax)3N4:Eu2+ Red Phosphors at Extreme Conditions for Application in Light-Emitting Diodes
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Structural Evolution and Effect of the Neighboring Cation on the Photoluminescence of Sr(LiAl 3 ) 1− x (SiMg 3 ) x N 4 :Eu 2+ Phosphors
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Calculations of labyrinth seals with and without diagnostic extraction in fluid-flow machines
PublicationLabyrinth seals are essential components of steam turbine unit constructions. Two types of labyrinth seals can be named, the first of which is the seal without diagnostic steam extraction, and the second – with extraction. The distribution of flow parameters along the packing is affected remarkably by the average seal clearance. The presence of diagnostic extraction leads to the equation system which is determinable and can be...
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Rekuperace elektrické energie v MHD
PublicationAsynchronní pohony, motory BLDC, trakční invertory, IGBT tranzistory, rekuperace energie – to jsou hesla, se kterými se můžeme často potkat, když si pročteme propagační materiály výrobců moderních tramvají a trolejbusů. Často se nám tyto prvky jeví jako indikátory hypermoderních technologií, ale ve skutečnosti se stává, že pod některými názvy se skrývá řešení známé inženýrům už dlouhá desetiletí. Tak je tomu také s rekuperací elektrické...
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Optimization of a novel procedure for determination of VOCs in water and human urine samples based on SBSE coupled with TD-GC-HRMS.
PublicationPodczas ozanczania lotnych związków chlorowcoorganicznych (t.j. bromodichlorometanu, dibromochlorometanu, bromoformu I tetrachloroetylenu) z próbek wody I moczu ludzkiego wykorzystano technikę ekstrakcji za pomocą ruchomego elementu sorpcyjnego typu Twister połączonego z desorpcją termiczną analitów do kolumny chromatografu gazowego wyposażonego w wysokosprawny spektrometr mas. Przeprowadzono optymalizację czasu (30 min) i prędkości...
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A new optimal algorithm for a time-dependent scheduling problem
PublicationIn this article a single machine time-dependent scheduling problem with total completion time criterion is considered. There are n given jobs j_1, ..., j_n and the processing time pi of the i-th job is given by p_i = 1 + b_is_i, where si is the starting time of the i-th job, i = 1, ..., n. If all jobs have different and non-zero deterioration rates and bi > bj => bi >= (b_min+1)/(b_min) b_j + 1/b_min, where b_min = min{b_i}, then...
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Stanowisko badawcze oraz wyniki badań silnika satelitowego zasilanego emulsją wodno-olejową
PublicationWiększość hydraulicznych układów napędowych obecnie jest zasilanych olejami. Ale olej jako medium robocze nie może być stosowany wszędzie tam, gdzie istnieje ryzyko pożaru. Dlatego też są stosowane trudnopalne i niepalne ciecze hydrauliczne jako emulsje, mikroemulsje i roztwory. W referacie opisano stanowisko badawcze zaprojektowane i zbudowane w Katedrze Hydrauliki i Pneumatyki Politechniki Gdańskiej, przedstawiono wyniki badań...
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Nanocrystalline Polymer Impregnated [Fe(pz)Pt(CN)4] Thin Films Prepared by Matrix-Assisted Pulsed Laser Evaporation
PublicationIn this work, the fabrication of [Fe(pz)Pt(CN)4] (pz = pyrazine) thin films by means of matrix-assisted pulsed laser evaporation (MAPLE) was investigated. As starting material, a cryogenically cooled suspension of anocrystalline [Fe(pz)Pt- (CN)4] (0.35wt.-%) in a mixture of 1,1-dichloroethane and polyethylene glycol (PEG) was used. Films of a thickness up to 150–200 nm were deposited on Si substrates by laser ablation at λ = 1064...
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(4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
PublicationSome inverse agonists of cannabinoid receptor type 1 (CB1) have been demonstrated to be anorectic antiobesity drug candidates. However, the first generation of CB1 inverse agonists, represented by rimonabant (SR141716A), otenabant, and taranabant, are centrally active, with a high level of psychiatric side effects. Hence, the discovery of CB1 inverse agonists with a chemical scaffold distinct from these holds promise for developing...
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Stalowe dwupłaszczowe zbiorniki na paliwa - interakcja konstrukcji stalowej z podłożem gruntowym
PublicationStalowe walcowe zbiorniki o osi pionowej są często wykorzystywane do magazynowania cieczy w rafineriach i przemyśle. Wielokrotnie rafinerie i bazy paliw zlokalizowane są w pobliżu portów w dolinach rzek, gdzie w podłożu często zalegają grunty słabonośne. Prezentowane badania wykonano w odpowiedzi na rzeczywisty problem z osiadaniami zbiorników, który wystąpił w jednej z polskich rafinerii. Przeanalizowano wpływ osiadań na pracę...
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Ocena odcinków prostych trasy kolejowej na podstawie pomiarów satelitarnych
PublicationW pracy przedstawiono kolejny moduł opracowywanego w Politechnice Gdańskiej programu komputerowego SATTRACK do wizualizacji, oceny i projektowania trasy kolejowej, dostosowanego do techniki ciągłych pomiarów satelitarnych. Jest to moduł TRACK_STRAIGHT, służący do oceny odcinków prostych. Pokazano opis jego funkcjonowania oraz przykłady zastosowania odpowiednich funkcji. Zapisane w pliku tekstowym współrzędne prostej wykorzystuje...
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Wybrane aspekty modelowania matematycznego kolejowego odbieraka prądu
PublicationNieprawidłowa współpraca odbieraka z siecią jezdną, w niekorzystnych warunkach lokalnych, prowadzi do uszkodzeń sieci lub odbieraka. Może być to spowodowane niewłaściwym wykonaniem lub utrzymaniem tych istotnych elementów układu zasilania. Tego typu sytuacje awaryjne powodują duże opóźnienia w ruchu pociągów i generują olbrzymie koszty. Wskazuje to na duże znaczenie odpowiednich rozwiązań konstrukcyjnych sieci i odbieraków oraz...
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DETERMINATION OF SEAKEEPING PERFORMANCE FOR A CASE STUDY VESSEL BY THE STRIP THEORY METHOD
PublicationThe increase of seakeeping performance is of particular importance for car and passenger ferries, service ships in the gas and oil extraction industry and offshore wind power farm industry, as well as for special purpose ships (including military applications). In the water areas of the Baltic Sea, North Sea, and Mediterranean Sea, which are characterised by a short and steep wave, the hull shape has a substantial impact on the...
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Context-aware User Modelling and Generation of Recommendations in Recommender Systems
PublicationRecommender systems are software tools and techniques which aim at suggesting new items that may be of interest to a user. This dissertation is focused on four problems in recommender systems domain. The first one is context-awareness, i.e. how to obtain relevant contextual information, how to model user preferences in a context and use them to make predictions. The second one is multi-domain recommendation, which aim at suggesting...
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Projektowanie i eksploatacja dróg szynowych z wykorzystaniem mobilnych pomiarów satelitarnych
PublicationNiniejsza monografia zawiera szczegółowy opis aktywnych sieci geodezyjnych GNSS oraz modelowania dokładności określania pozycji w pomiarach satelitarnych. Omówiono również opracowaną technikę mobilnych pomiarów satelitarnych toru kolejowego oraz aplikacje związane z jej zastosowaniem w projektowaniu i eksploatacji dróg szynowych. Autorzy zawarli w pracy wyniki swoich badań, wykonywanych na przestrzeni lat 2009–2015. Badania przeprowadzono...
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Curved Surface Minijet Impingement Phenomena Analysed with ζ-f Turbulence Model
PublicationThe jet impingement phenomenon plays an important role among the heat transfer intensification methods. Very often its application and analyses refer to simple flat surfaces, while there is a lack of information in the literature for cases addressing curved surfaces. In the present work, the single jet impingement on the non-flat (concave and convex) surface is studied for a wide range of geometries, which originate from the mini-jet...
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The Spatial Structure of Suburban Zones in Selected Entrepreneurship Nets of the Tricity Metropolitan Area
PublicationThe chapter describes spatial structures and forms of Polish suburban zones shown on the example of two selected towns in the Trojmiasto Metropolitan Area (TMA). The description of the spatial characteristics in the urban sprawl, with focus on the entrepreneurships nests is illustrated by the choice of typological features, such as: form, land use, density. Suburbanisation is described to be global, however one can observe individual...
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Medical-Grade PCL Based Polyurethane System for FDM 3D Printing—Characterization and Fabrication
PublicationThe widespread use of three-dimensional (3D) printing technologies in medicine has contributed to the increased demand for 3D printing materials. In addition, new printing materials that are appearing in the industry do not provide a detailed material characterization. In this paper, we present the synthesis and characterization of polycaprolactone (PCL) based medical-grade thermoplastic polyurethanes, which are suitable for forming...
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Machine learning-based prediction of seismic limit-state capacity of steel moment-resisting frames considering soil-structure interaction
PublicationRegarding the unpredictable and complex nature of seismic excitations, there is a need for vulnerability assessment of newly constructed or existing structures. Predicting the seismic limit-state capacity of steel Moment-Resisting Frames (MRFs) can help designers to have a preliminary estimation and improve their views about the seismic performance of the designed structure. This study improved data-driven decision techniques in...
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Experimentelle und numerische Untersuchungen zum Tragverhalten von Stahlbetondecken mit kugelförmigen Hohlkörpern
PublicationBetonowe stropy płaskie sprawdzają się jako system stropowy zarówno w budownictwie ogólnym, jak i przemysłowym. Duży ciężar własny tych stropów może jednak ograniczać ich obszar zastosowań. Ta wada może zostać istotnie ograniczona poprzez zastosowanie pustek powietrznych w strefie osi obojętnej płyty. Redukując w ten sposób zużycie betonu i stali zbrojeniowej tworzy się dodatkowo bardziej ekologiczny system budowy.Pustki powietrzne...
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Kalibracja i walidacja metody Mathara za pomocą Metody Elementów Skończonych
PublicationMetoda pomiaru naprężeń powierzchniowych przy pomocy rozet tensometrycznych i kontrolowanych odwiertów (metoda otworkowa) jest stosowana powszechnie w odniesieniu do stali izotropowych oraz silnie anizotropowych laminatów, natomiast nie została rozpoznana jej stosowalność do umiarkowanie anizotropowych stopów metali. W artykule opisane jest odniesienie wyników pomiarów wykonanych na płytach ze stali duplex do modelu numerycznego...
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Łuk Białostocki
PublicationArtykuł prezentuje oddany do użytkowania w czerwcu 2011 wiadukt drogowy ,,Łuk Białostocki”. Konstrukcja ta z uwagi na lokalizację dźwigara łukowego względem osi pomostu – po przekątnej, jest w Polsce w swojej skali obiektem prototypowym. Ustrój nośny obiektu stanowi stalowy bezprzegubowy dźwigar łukowy, usytuowany w rzucie z góry po krótszej przekątnej konstrukcji, z podwieszonym za pomocą cięgien pomostem zespolonym. Rozpiętość...
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A fast and convenient method for analysis of collagen hydrolysis products Szybka i dogodna metoda analizy produktów hydrolizy kolagenu
PublicationPolypeptides produced by hydrolysis of collagen from minced animal hide and skin scraps were studied by mass spectrometry (MS) in conjunction with electrophoresis to det. their mol. mass. The degree of peptides ionisation was ca 50+. This allowed for observation of the large polypeptide chains with mass analyzers with a relatively low m/z range. The electrospray and atm. pressure photoionization techniques were used. The polypeptide...
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Identification and characterization of the Indian Yellow dyestuff and its degradation products in historical oil paint tube by liquid chromatography mass spectrometry
PublicationAn analytical protocol for identification of dyes using reversed phase liquid chromatography-mass spectrometry with atmospheric pressure electrospray ionization (LC-ESI/MS) is presented. The developed method has been successfully applied in identification of euxanthic acid and euxanthone, the main components of the Indian Yellow dye in a historical oil paint tube produced by Richard Ain`es, a recognizable French company supplying...
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LC-MS/MS dtermination of isoprostanes in plasma samples collected from mice exposed to doxorubicin or tert-butyl hydroperoxide
PublicationIsoprostanes are stable products of arachidonic acid peroxidation and are regarded as the most reliable markers of oxidative stress in vivo. Here we describe the LC-MS/MS procedure enabling simultaneous determination of four regioisomers (8-iso prostaglandin F2α, 8-iso-15(R)-prostaglandin F2α, 11β-prostaglandin F2α, 15(R)-prostaglandin F2α) in plasma samples collected from mice. The four plasma isoprostanes are determined by LC–ESI-MS/MS...
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Analiza topologii uzwojenia stojana w części czołowej maszyny indukcyjnej przy wykorzystaniu algorytmu genetycznego.
PublicationW pracy przedstawiono zagadnienia analizy topologii uzwojenia stojana silnika asynchronicznego posiadającego uzwojenie wykonane z cewek giętkich. Znajomość geometrii takich uzwojeń jest niezbędna w celu wykonania dokładniejszych obliczeń cieplnych, elektromagnetycznych i mechanicznych wykonanych za pomocą programów polowych. W celu odwzorowania rzeczywistej topologii uzwojenia autorzy zaproponowali wykorzystanie algorytmu genetycznego...
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Expression of a GDSL esterase from Pseudomonas sp. S9 in Pichiapastoris
PublicationCold active lipolytic enzymes are promising to replace the conventional enzymes processes of biotechnological industries. One of the most important feature of the cold-active lipases and esterases is that they offer economic benefits through energy saving. In general, they exhibit high activity at low temperatures and low thermostability at moderate temperatures. Lipolytic enzyme EstS9 was isolated from Pseudomonas sp. S9. A multiple...
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Multi-Technique Investigation of Grave Robes from 17th and 18th Century Crypts Using Combined Spectroscopic, Spectrometric Techniques, and New-Generation Sequencing
PublicationThe textile fragments of the funeral clothes found in the 17th and 18th century crypts were subjected to spectroscopic, spectrometric, and microbial investigation. The next-generation sequencing enabled DNA identification of microorganisms at the genus and in five cases to the species level. The soft hydrofluoric acid extraction method was optimized to isolate different classes of dyes from samples that had direct contact with...
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Study of the Performance of DSSS UAC System Depending on the System Bandwidth and the Spreading Sequence
PublicationA signal transmitted in an Underwater Acoustic Communication (UAC) system operating in a shallow-water channel suffers from strong time dispersion due to multipath propagation. This causes the Inter-Symbol Interference (ISI) observed in the received signal, which significantly limits the communication system’s reliability and transmission rate. In such propagation conditions, the Direct-Sequence Spread Spectrum (DSSS) method is...
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Red Kale (Brassica oleracea L. ssp. acephala L. var. sabellica) Induces Apoptosis in Human Colorectal Cancer Cells In Vitro
PublicationThis article presents the results of studies investigating the effect of red kale (Brassica oleracea L. ssp. acephala L. var. sabellica) extract on cancer cells (HT-29). The cytotoxicity of the red kale extract was assessed using MTT and LDH assays, while qRT-PCR was employed to analyze the expression of genes associated with the p53 signaling pathway to elucidate the effect of the extract on cancer cells. Furthermore, HPLC-ESI-QTOF-MS/MS...
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Ultrasound-Assisted Solvent Extraction of a Porous Membrane Packed Sample for the Determination of Tobacco-Specific Nitrosamines in the Replacement Liquids for E-Cigarettes
PublicationThe content of tobacco-specific nitrosamines (TSNAs) possessing carcinogenic properties has been an important area of research since replacement liquids were introduced for e-cigarettes. A method for determining N′-nitrosonornicotine (NNN), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), N′-nitrosoanatabine (NAT), and N′-nitrosoanabasine (NAB) in replacement liquids for electronic cigarettes was developed using liquid chromatography–tandem...