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Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublicationEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
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Wysokopoziomowy model projektowania wskaźników KPI systemów inteligentnych miast
PublicationCelem pracy jest prezentacja etapów budowy wysokopoziomowych modeli projektowania wskaźników KPI (WPMPW) systemów inteligentnych miast. Dotychczasowy rozwój, badanie procesów miast i przyporządkowanie im miar może być kontrolowane za pomocą wskaźników KPI. Autorzy pracy w trakcie procesów projektowania zwrócili uwagę na ograniczoną użyteczność tak projektowanych wskaźników dla przedstawicieli miast. Stąd też zaproponowali koncepcję...
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A stochastic approach for the solution of single and multi – objective optimisation problems of biological processes in sequencing batch reactor
PublicationThis paper investigates the impact of implementing single and multi-optimisation solutions on the biological treatment process in a sequencing batch reactor (SBR). The research is based on a case study of the water resource recovery facility (WRRF) in Swarzewo, Northern Poland. The paper introduces the adaptive extremum seeking control (ESC) method for dissolved oxygen (DO) concentration control and places it in a layered control structure....
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Separation of C6 hydrocarbons on sodium dithionite reduced graphene oxide aerogels
PublicationThe ability of reduced graphene oxide aerogels (rGOAs) for challenging gas-phase separation was investigated with hexane isomers and benzene (C6 hydrocarbons) using inverse gas chromatography (IGC). For the first, rGOAs were synthesized with sodium dithionite (DTN) as a reductant. Experiments revealed that the most optimal DTN to graphene oxide mass ratio was 2:1, resulting in the highest specific surface area of 432.3 m2 g−1 and...
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Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent
PublicationCarbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental methods were used, e.g., potentiometric, spectroscopic (ATR, UV, XRD powder,1H and13C NMR), electrochemical (cyclic voltammetry), and...
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Współczesne metody zapewniania jakości oprogramowania. Od klasyki do zwinności
PublicationKsiążka opisuje problematykę jakości w kontekście metod wytwarzania oprogramowania. Składa się z 22 rozdziałów podzielonych na 6 części: Znaczenie jakości oprogramowania, Podstawowe pojęcia i problemy jakości, Jakość w ujęciu klasycznym, Pomiary jakości, Dokumentacja i normy jakości procesu, Jakość w podejściu zwinnym. Zebrany materiał pokazuje ewolucję podejścia do jakości w klasycznych metodykach wytwarzania (od modelu kaskadowego...
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Supervisory control of integrated wastewater treatment systems.
PublicationSterowanie zintegrowanym systemem oczyszczania ścieków (sieć kanalizacyjna- oczyszczalnia ścieków), w pełnym zakresie jego obciążeń wymaga zastosowania zaawansowanych algorytmów sterowania optymalizującego. System sterowania jest hierarchicznie zdekomponowany, tworząc wielopoziomową-wielowarstwową. Główną technologią sterowania sterowanie predykcyjne (MPC). Nie jest możliwe wystarczająco efektywne sterowanie takim systemem we wszystkich...
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Softly switched model predictive control for control of integratedwastewater treatment system at medium time scale.
PublicationW przypadku gdy system jest sterowany za pomocą jednej, uniwersalnej strategii sterowania w pełnym zakresie jego obciążeń, powstają poważne trudności w znalezieniu optymalnego sterowania. W celu jak najlepszego dopasowania strategii sterowania do panujący warunków, zdefiniowano trzy stany operacyjne: normalny, zakłóceniowy oraz awaryjny. Dla tych stanów zaprojektowano odpowiednie strategie sterowania. W związku z tym pojawia się...
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Set-Bounded joined parameter and state estimation for model predictive control of integrated wastewater treatment plant systems at medium time scale.
PublicationW artykule opisano moduł łącznej estymacji w postaci zbiorów ograniczonych (ang. set-bounded) parametrów i stanu systemu dla potrzeb sterowania predykcyjnego zintegrowanym systemem ściekowym w średniej skali czasu. Jest to jeden ze składowych elementów Inteligentnej Hierarchicznej Struktury Sterowania opracowanej w celu pokonania następujących problemów, które występują w kontrolowanym systemie: różne skale czasowe procesów, silnie...
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Investigation of the Antifungal Activity and Mode of Action of Thymus vulgaris, Citrus limonum, Pelargonium graveolens, Cinnamomum cassia, Ocimum basilicum, and Eugenia caryophyllus Essential Oils
PublicationThe antimicrobial activity of plant oils and extracts has been recognized for many years. In this study the activity of Thymus vulgaris, Citrus limonum, Pelargonium graveolens, Cinnamomum cassia, Ocimumbasilicum, and Eugenia caryophyllus essential oils (EOs) distributed by Pollena Aroma (Nowy Dwór Mazowiecki, Poland) was investigated against a group of 183 clinical isolates of C. albicans and 76 isolates of C. glabrata. All of...
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The Influence of External Load on the Performance of Microbial Fuel Cells
PublicationIn this work, the effect of the external load on the current and power generation, as well as on the pollutant removal by microbial fuel cells (MFCs), has been studied by step-wise modifying the external load. The load changes included a direct scan, in which the external resistance was increased from 120 Ω to 3300 Ω, and a subsequent reverse scan, in which the external resistance was decreased back to 120 Ω. The reduction in the...
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The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
PublicationMatrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...
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The Interaction of Heptakis (2,6-di-O-Methyl)-β-Cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity
PublicationOne tetracyclic antidepressant, mianserin hydrochloride (MIA), has quite significant side effects on a patients’ health. Cyclodextrins, which are most commonly used to reduce the undesirable features of contained drugs within their hydrophobic interior, also have the potential to alter the toxic behavior of the drug. The present paper contains investigations and the characteristics of interaction mechanisms for MIA and the heptakis...
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Novel 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives as potent anticancer agents – Synthesis, molecular structure, QSAR studies and metabolic stability
PublicationA series of new 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives have been synthesized and evaluated in vitro by MTT assays for their antiproliferative activity against cell lines of colon cancer HCT-116, cervical cancer HeLa and breast cancer MCF-7. The obtained results indicated that these compounds display prominent cytotoxic effect. The best anticancer properties have been observed for derivatives...
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Robustly feasible integral LQ-MPC controller for output tracking in constrained linear systems
PublicationW pracy rozważany jest regulator predykcyjny typu dual-mode MPC z liniowo kwadratowym wskaźnikiem jakości w aplikacji do krzepkiego śledzenia wyjść liniowego obiektu dyskretnego w obecności addytywnych zakłóceń. W celu zapewnienia dopuszczalności sterowań regulatora wykorzystano teorię zbiorów niezmienniczych. W celu polepszenia śledzenia wyjść i odrzucenia zakłóceń w regulatorze wykorzystano działanie całkujące (integral control)....
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Comparison of the content of phenolic compounds and antioxidant activity of white, red and black currants (Ribes sp.) extracts
PublicationThe aim of this study was to compare the content of antioxidant compounds and the antioxidant activity of extracts from white, red and black currants (Ribes sp.). The chemical properties verified included determinations of anthocyanins and other phenols by HPLC-DAD-MS, total antioxidant activity by standard spectrophotometric tests (ABTS, DPPH and FCR), and profiles of antioxidants by TLC with visualization reagents (ABTS, DPPH,...
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The impact of initial and boundary conditions on severe weather event simulations using a high-resolution WRF model. Case study of the derecho event in Poland on 11 August 2017
PublicationPrecise simulations of severe weather events are a challenge in the era of changing climate. By performing simulations correctly and accurately, these phenomena can be studied and better understood. In this paper, we have verified how different initial and boundary conditions affect the quality of simulations performed using the Weather Research and Forecasting Model (WRF). For our analysis, we chose...
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Wykorzystanie algorytmu ewolucyjnego i logiki rozmytej do kierowania statkiem
PublicationRozwój technik komputerowych w ostatnich latach, wpłynął na zmiany w sposobie prowadzenia nawigacji na współczesnym statku floty handlowej. Dysponując doświadczeniami związanymi z zatonięciem promu ''Estonia'', pod pokładem którego życie utraciły 852 osoby (95 ciał odnaleziono, 757 uznano za zaginione) oraz innych jednostek morskich, opracowano Konwencję STCW-95 nakładającą na oficerów nawigacyjnych i personel pokładowy, obowiązek...
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Model predictive controller for integrated wastewater treatment systems.
PublicationSterowanie optymalizujace systemem oczyszczania ścieków (WWTS) pozwala na zmniejszenie kosztów operacyjnych przy jednoczesnym spełnieniu narzuconych ograniczeń na wypływające ścieki, jednak wymaga zaawansowanych technologii sterowania. Sterowanie predykcyjne z modelem (MPC) jest bardzo użyteczną technologią sterowania takimi systemami. MPC doskonale radzi sobie z obecnością ogrniczeń na wielkości wyjściowe, wielowymiarowością problemu...
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A Robust Random Forest Model for Classifying the Severity of Partial Discharges in Dielectrics
PublicationPartial Discharges (PDs) are a common source of degradation in electrical assets. It is essential that the extent of the deterioration level of insulating medium is correctly identified, to optimize maintenance schedules and prevent abrupt power outages. Temporal PD signals received from damaged insulation, collected through the IEC-60270 method is the gold standard for PD detection. Temporal signals may be transformed to the frequency...
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Mixed integer nonlinear optimization of biological processes in wastewater sequencing batch reactor
PublicationWastewater treatment plays a key role for humanity. The waste entering lakes, rivers, and seas deteriorates daily quality of life. Therefore, it is very important to improve the efficiency of wastewater treatment. From a control point of view, a biological wastewater treatment plant is a complex, non-linear, multidimensional, hybrid control system. The paper presents the design of the optimizing hierarchical control system applied...
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Antifungal Activity and Synergism with Azoles of Polish Propolis
PublicationThe aim of our work was to check if one of the products of natural origin, namely honey 19 bee propolis may be an alternative or supplement to currently used antifungal agents. The activity 20 of 50 ethanolic extracts of propolis (EEPs), harvested in Polish apiaries, was tested on a group of 69 21 clinical isolates of C. albicans. Most of the EEPs showed satisfactory activity, with minimum 22 fungicidal concentrations (MFC) mainly...
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Ontology of the Design Pattern Language for Smart Cities Systems
PublicationThe paper presents the definition of the design pattern language of Smart Cities in the form of an ontology. Since the implementation of a Smart City system is difficult, expensive and closely linked with the problems concerning a given city, the knowledge acquired during a single implementation is extremely valuable. The language we defined supports the management of such knowledge as it allows for the expression of a solution...
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Electrifying the bus network with trolleybus: Analyzing the in motion charging technology
PublicationCurrently, electric buses are becoming more and more popular, and their number in operation is increasing. The range of electric buses is also increasing and solutions that seem to be working almost without fixed infrastructure are being promised. However, this requires the use of high-capacity batteries, which increases the weight and price of the vehicle and causes high costs of battery replacement during operation. Moreover,...
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Possibilities for Developing Electromobility by Using Autonomously Powered Trolleybuses Based on the Example of Gdynia
PublicationTrolleybus transport refers to contemporary challenges related to a reduction in emissions of greenhouse gases and CO2 into the atmosphere formulated by international institutions, such as the United Nations, the Organisation for Security and Co-operation in Europe, or the European Union. Departure from fossil fuels in urban transport is one of the key challenges for the coming years. Trolleybuses are an important tool in this...
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IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection
PublicationCellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction factors (RFs) able to exert a protective effect against invading pathogens, we asked whether a similar defense mechanism would also be in place to preserve the metabolic compartment from HCMV...
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BODIPY‐Perylene Charge Transfer Compounds; Sensitizers for Triplet‐Triplet Annihilation Up‐conversion
PublicationBODIPY heterochromophores, asymmetrically substituted with perylene and/or iodine at the 2 and 6 positions were prepared and investigated as sensitizers for triplet-triplet annihilation up conversion (TTA-UC). Single-crystal X-ray crystallographic analyses show that the torsion angle between BODIPY and perylene units lie between 73.54 and 74.51, though they are not orthogonal. Both compounds show intense, charge transfer absorption...
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The Influence of COD Fraction Forms and Molecules Size on Hydrolysis Process Developed by Comparative OUR Studies in Activated Sludge Modelling
PublicationThe activated sludge models (ASMs) commonly used by the International Water Association (IWA) task group are based on chemical oxygen demand (COD) fractionations. However, the proper evaluation of COD fractions, which is crucial for modelling and especially oxygen uptake rate (OUR) predictions, is still under debate. The biodegradation of particulate COD is initiated by the hydrolysis process, which is an integral part of an ASM....
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Coffee Silverskin as a Multifunctional Waste Filler for High-Density Polyethylene Green Composites
PublicationThis work aims to describe the coffee silverskin effect as a lignocellulosic waste filler for high-density polyethylene (HDPE) composites development. The main task was to determine various modification effects resulting from the complex chemical composition of coffee silverskin containing compounds with potential antioxidative properties, including caffeine, polyphenols, tannins, or melanoidins. The processing, thermal, physicochemical,...
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Laser Welding of UNS S33207 Hyper-Duplex Stainless Steel to 6061 Aluminum Alloy Using High Entropy Alloy as a Filler Material
PublicationThe high entropy alloy (HEA) filler used during the fabrication method determines the reliability of HEAs for steel-aluminum dissimilar alloy configuration. HEAs have a direct impact on the formation of intermetallic compounds (IMC) formed by the interaction of iron (Fe) and aluminum (Al), and influence the size of the joint’s interaction zone. A novel welding process for Fe-Al alloy joints was developed to prevent the development...
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Advanced Control With PLC—Code Generator for aMPC Controller Implementation and Cooperation With External Computational Server for Dealing With Multidimensionality, Constraints and LMI Based Robustness
PublicationThe manufacturers of Programmable Logic Controllers (PLC) usually equip their products with extremely simple control algorithms, such as PID and on-off regulators. However, modern PLCs have much more efficient processors and extensive memory, which enables implementing more sophisticated controllers. The paper discusses issues related to the implementation of matrix operations, time limitations for code execution within one PLC...
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Activity of Patents in Fuel Cells and Hydrogen Production in the Context of Passenger Car Fleet in the V4 Countries
PublicationThe hydrogen market in the world today is capable ovule and em-pirical evidence on activity of patents in fuel cells and hydrogen production islimited so far. Patent applications in zero-emission mobility in the aspect of fuelcells include: DAFC/DMFC&DMFC, PEMFC, SOFC, AFC, PAFC. As for thepatents relating to the hydrogen production, they concern low carbon, electrol-ysis and inorganic. The purpose of the study was to investigate...
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A socially responsible university - an attempt to approach the system
PublicationIt is the author's thesis that social responsibility of university is an integrated system of both knowledge management (KM), quality management (QM) and organizational development (OD) processes. The author determined that the university "bond" is an institutional culture (IC). An integrated system is the way to create university an open system co-operated and co-opetited with stakeholders. The stakes are high in game - both students...
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COMPOSITION OF BIOACTIVE SECONDARY METABOLITES AND MUTAGENICITY OF SAMBUCUS NIGRA L. FRUIT AT DIFFERENT STAGES OF RIPENESS
PublicationThe relationship between the content of bioactive compounds and mutagenic activity of elderberry fruit at different stages of ripeness was investigated. Signifi cant differences in the antioxidant profi les (TLC, HPLC with post-column derivatization) and antioxidant activity (ABTS, DPPH, and FC tests) were observed for studied elderberry extracts. The more ripen the fruit at the time of harvest were, the higher the content of...
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Integrated controller for ultra high frequency technique laboratory
PublicationDepartment of Microwave and Antenna Engineering decided to modernize the laboratory of Ultra High Frequency Techniques. The main change was to replace measurement of the field distribution inside rectangular waveguides by analysing the fields around striplines. This involved the need to overcome several technical and conceptual problems. Precise positioning of the probe and reading the field distribution near the stripline is important...
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Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection
PublicationA simple and accurate ion chromatography (IC) method with pulsed amperometric detection (PAD) was proposed for the determination of cyanide ion in urine, sweat, and saliva samples. The sample pretreatment relies on alkaline digestion and application of Dionex OnGuard II H cartridge. Under the optimized conditions, the method showed good linearity in the range of 1–100 μg/L for urine, 5–100 μg/L for saliva, and 3–100 μg/L for sweat...
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Development of fragility curves in adjacent steel moment-resisting frames considering pounding effects through improved wavelet-based refined damage-sensitive feature
PublicationFragility curves present useful information related to earthquake-induced probability assessment of steel moment-resisting frames (MRFs) and determine the probability of the damage exceedance at different floor levels of MRFs. The review of the literature shows that most of the previous studies dealing with the fragility curves were based on conventional measures, such as spectral acceleration at the first mode period, peak...
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Monitorowanie i modelowanie zjawisk z wieloma skalami czasu do potrzeb sterowania w zastosowaniu do oczyszczalni ścieków
PublicationOstatnie dwanacie miesięcy przeznaczyłem na kończenie rozprawy doktorskiej oraz pisanie dwóch artykułów na ALSIS' 06 (1st IFAC Workshop on Applications of Large Scale Industrial Systems), który odbędzie się w dniach 30 - 31 sierpnia w Helsinkach i Sztokholmie. Oba artykuły [1,2] zostały przyjęte i będę je prezentował podczas warsztatów ALSIS'06. Artykuł [1] zawiera częciowe wyniki pracy dotyczšce budowy modelu oczyszczalni cieków...
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MATHEMATICAL MODELING OF FLOOD MANAGEMENT SYSTEM IN THE CITY OF GDAŃSK, ORUŃSKI STREAM CASE STUDY
PublicationAim of the study This study analyses the efficiency of flood protection in a small urban catchment, based on a system of small reservoirs. Material and methods To assess the flood routing and surge reduction, a mathematical model of the river catchment was implemented. This was a lumped hydrological model, based on the SCS-CN method. Channel routing was performed, using kinematic wave equation. The sub-catchments have been determined...
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Visually validated semi-automatic high-frequency oscillation detection aides the delineation of epileptogenic regions during intra-operative electrocorticography
PublicationOBJECTIVE: To test the utility of a novel semi-automated method for detecting, validating, and quantifying high-frequency oscillations (HFOs): ripples (80-200 Hz) and fast ripples (200-600 Hz) in intra-operative electrocorticography (ECoG) recordings. METHODS: Sixteen adult patients with temporal lobe epilepsy (TLE) had intra-operative ECoG recordings at the time of resection. The computer-annotated ECoG recordings were visually...
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Potential for ITS/ICT Solutions in Urban Freight Management
PublicationThe article presents a study on applying ITS solutions in planning and management of urban freight transport in Gdynia. The traffic management system Tristar which is under implementation and its related systems show a potential to assist in development of freight transport measures. Recommendations for urban freight policy development supplementing Gdynia's Sustainable Urban Mobility Plan were used as a basis for identification...
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Realizacja programowa algorytmów filtracji, estymacji i sterowania w PLC/PAC
PublicationSterowniki programowalne PLC (ang. Programmable Logic Controller) są główną przemysłową platformą implementacji algorytmów sterowania bezpośredniego. Standardowo producenci PLC dostarczają programistom jedynie podstawowe, najprostsze metody sterowania. Wraz z rozwojem sterowników PLC oraz ich następców PAC (ang. Programmable Automation Controller) pojawiły się zwiększone możliwości obliczeniowe i pamięciowe tych urządzeń oraz...
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Post-Effort Changes in Autophagy- and Inflammation-Related Gene Expression in White Blood Cells of Healthy Young Men
PublicationAcute, strenuous physical exertion requiring high levels of energy production induces the production of reactive oxygen species and metabolic disturbances that can damage the mitochondria. Thus, selective autophagic elimination of defective mitochondria may improve resistance to oxidative stress and potentially to inflammation. The main goal of this study was to evaluate the impacts of intense effort on changes in the expression...
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Widening of the electroactivity potential range by composite formation – capacitive properties of TiO2/BiVO4/PEDOT:PSS electrodes in contact with an aqueous electrolyte
PublicationComposites based on the titania nanotubes were tested in aqueous electrolyte as a potential electrode material for energy storage devices. The nanotubular morphology of TiO2 was obtained by Ti anodization. TiO2 nanotubes were covered by a thin layer of bismuth vanadate using pulsed laser deposition. The formation of the TiO2/BiVO4 junction leads to enhancement of pseudocapacitance in the cathodic potential range. The third component,...
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Validation of atmospheric aerosols sampling in equivalent fractions
PublicationPhysical properties and chemical composition of atmospheric aerosols are of extreme importance, in many fields of interest, namely the Environment even with legal implications. Atmospheric sampling poses inherent problems with consequent demands on sampling optimisation, with sampling strategies requiring validation. In this work a study was conducted aiming at validating the collection of atmospheric aerosols in equivalent fractions....
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Validation of atmospheric aerosols parallel sampling in a multifold device
PublicationIn this work, particulate matter was collected using an active sampling system consisting of a PM10 (<10 μm) inlet coupled to a multifold device containing six channels, connected to a vacuum pump. Each channel was equipped with a filter holder fitted with adequately chosen filters. The system was fixed on a metallic structure, which was placed on the roof of the laboratory building, at the Faculty of Sciences, in Lisbon. Sampling...
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A solid phase extraction–ion chromatography with conductivity detection procedure for determining cationic surfactants in surface water samples
PublicationA new analytical procedure for the simultaneous determination of individual cationic surfactants (alkyl benzyl dimethyl ammonium chlorides) in surface water samples has been developed. We describe this methodology for the first time: it involves the application of solid phase extraction (SPE – for sample preparation) coupled with ion chromatography–conductivity detection (IC-CD – for the final determination). Mean recoveries of...
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Ontologia języka wzorców projektowych dla systemów Smart Cities
PublicationW artykule przedstawiono definicję języka wzorów projektowych Smart Cities w postaci ontologii. Jako, że wdrażanie rozwiązania Smart City jest trudne, drogie i ściśle związane z problematyką dotycząca danego miasta, wiedza nabywana podczas pojedynczego wdrożenia jest wiedzą niezwykle cenną. Zdefiniowany przez nas język wspiera zarządzanie ww. wiedzą jako, że pozwala on na ekspresję rozwiązania, które bazując na najlepszych praktykach...
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Kwaternionowy system kryptograficzny dla zabezpieczania danych multimedialnych
PublicationProblemem badawczym, którego dotyczy rozprawa jest kryptograficzne zabezpieczanie danych multimedialnych, głównie obrazów i sygnałów video, przed działaniami niepowołanych osób i organizacji, chcących uzyskać do nich dostęp i mieć możliwość ich nielegalnego wykorzystania oraz modyfikacji. W rozprawie wykazano, że wykorzystanie właściwości rachunku kwaternionowego umożliwia zbudowanie kwaternionowego systemu kryptograficznego dla...
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Circulating miRNA profiles and the risk of hemorrhagic transformation after thrombolytic treatment of acute ischemic stroke: a pilot study
PublicationBackground: Hemorrhagic transformation (HT) in acute ischemic stroke is likely to occur in patients treated with intravenous thrombolysis (IVT) and may lead to neurological deterioration and symptomatic intracranial hemorrhage (sICH). Despite the complex inclusion and exclusion criteria for IVT and some useful tools to stratify HT risk, sICH still occurs in approximately 6% of patients because some of the risk factors for this...